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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LRP1-ETV6 (FusionGDB2 ID:49742)

Fusion Gene Summary for LRP1-ETV6

check button Fusion gene summary
Fusion gene informationFusion gene name: LRP1-ETV6
Fusion gene ID: 49742
HgeneTgene
Gene symbol

LRP1

ETV6

Gene ID

10438

2120

Gene nameC1D nuclear receptor corepressorETS variant transcription factor 6
SynonymsLRP1|Rrp47|SUN-CoR|SUNCOR|hC1DTEL|TEL/ABL|THC5
Cytomap

2p14

12p13.2

Type of geneprotein-codingprotein-coding
Descriptionnuclear nucleic acid-binding protein C1DC1D DNA-binding proteinC1D nuclear receptor co-repressornuclear DNA-binding proteinsmall unique nuclear receptor co-repressorsmall unique nuclear receptor corepressortranscription factor ETV6ETS translocation variant 6ETS variant 6ETS-related protein Tel1TEL1 oncogeneets variant gene 6 (TEL oncogene)
Modification date2020031320200313
UniProtAcc

Q07954

P41212

Ensembl transtripts involved in fusion geneENST00000243077, ENST00000338962, 
ENST00000553277, ENST00000554174, 
ENST00000553446, 		ENST00000544715, 
ENST00000396373, 
Fusion gene scores* DoF score23 X 27 X 12=745221 X 24 X 6=3024
# samples 2619
** MAII scorelog2(26/7452*10)=-4.84104414591318
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/3024*10)=-3.99238681589013
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LRP1 [Title/Abstract] AND ETV6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLRP1(57539273)-ETV6(12037379), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneETV6

GO:0000122

negative regulation of transcription by RNA polymerase II

10514502


check buttonFusion gene breakpoints across LRP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ETV6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-PC-A5DN-01ALRP1chr12

57539273

+ETV6chr12

12037379

+


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Fusion Gene ORF analysis for LRP1-ETV6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000243077ENST00000544715LRP1chr12

57539273

+ETV6chr12

12037379

+
5CDS-intronENST00000338962ENST00000544715LRP1chr12

57539273

+ETV6chr12

12037379

+
5CDS-intronENST00000553277ENST00000544715LRP1chr12

57539273

+ETV6chr12

12037379

+
5CDS-intronENST00000554174ENST00000544715LRP1chr12

57539273

+ETV6chr12

12037379

+
In-frameENST00000243077ENST00000396373LRP1chr12

57539273

+ETV6chr12

12037379

+
In-frameENST00000338962ENST00000396373LRP1chr12

57539273

+ETV6chr12

12037379

+
In-frameENST00000553277ENST00000396373LRP1chr12

57539273

+ETV6chr12

12037379

+
In-frameENST00000554174ENST00000396373LRP1chr12

57539273

+ETV6chr12

12037379

+
intron-3CDSENST00000553446ENST00000396373LRP1chr12

57539273

+ETV6chr12

12037379

+
intron-intronENST00000553446ENST00000544715LRP1chr12

57539273

+ETV6chr12

12037379

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000553277LRP1chr1257539273+ENST00000396373ETV6chr1212037379+601913134481662404
ENST00000243077LRP1chr1257539273+ENST00000396373ETV6chr1212037379+601313074421656404
ENST00000338962LRP1chr1257539273+ENST00000396373ETV6chr1212037379+579610902251439404
ENST00000554174LRP1chr1257539273+ENST00000396373ETV6chr1212037379+5603897321246404

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000553277ENST00000396373LRP1chr1257539273+ETV6chr1212037379+0.0015233450.9984767
ENST00000243077ENST00000396373LRP1chr1257539273+ETV6chr1212037379+0.0015260430.99847394
ENST00000338962ENST00000396373LRP1chr1257539273+ETV6chr1212037379+0.0012340980.99876595
ENST00000554174ENST00000396373LRP1chr1257539273+ETV6chr1212037379+0.0011934960.9988065

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Fusion Genomic Features for LRP1-ETV6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
LRP1chr1257539273+ETV6chr1212037378+1.30E-070.9999999
LRP1chr1257539273+ETV6chr1212037378+1.30E-070.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for LRP1-ETV6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:57539273/chr12:12037379)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LRP1

Q07954

ETV6

P41212

FUNCTION: Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells (PubMed:11907044, PubMed:12713657). Required for early embryonic development (By similarity). Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor (PubMed:26142438, PubMed:1702392). Acts as TAU/MAPT receptor and controls the endocytosis of TAU/MAPT as well as its subsequent spread (PubMed:32296178). May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission (PubMed:12888553). {ECO:0000250|UniProtKB:Q91ZX7, ECO:0000269|PubMed:11907044, ECO:0000269|PubMed:12713657, ECO:0000269|PubMed:12888553, ECO:0000269|PubMed:1702392, ECO:0000269|PubMed:26142438, ECO:0000269|PubMed:32296178}.; FUNCTION: (Microbial infection) Functions as a receptor for Pseudomonas aeruginosa exotoxin A. {ECO:0000269|PubMed:1618748}.FUNCTION: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation. {ECO:0000269|PubMed:25581430}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689111_1492804545.0DomainEGF-like 1
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689150_1892804545.0DomainEGF-like 2%3B calcium-binding
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+68925_662804545.0DomainLDL-receptor class A 1
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+68970_1102804545.0DomainLDL-receptor class A 2
TgeneETV6chr12:57539273chr12:12037379ENST0000039637348339_420336453.0DNA bindingETS

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891013_10532804545.0DomainLDL-receptor class A 7
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891060_10992804545.0DomainLDL-receptor class A 8
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891102_11422804545.0DomainLDL-receptor class A 9
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891143_11822804545.0DomainLDL-receptor class A 10
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891183_12222804545.0DomainEGF-like 5
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891223_12622804545.0DomainEGF-like 6
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891536_15792804545.0DomainEGF-like 7
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891846_18872804545.0DomainEGF-like 8
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892155_21952804545.0DomainEGF-like 9
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892478_25182804545.0DomainEGF-like 10
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892522_25632804545.0DomainLDL-receptor class A 11
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892564_26022804545.0DomainLDL-receptor class A 12
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892603_26412804545.0DomainLDL-receptor class A 13
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892642_26902804545.0DomainLDL-receptor class A 14
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892694_27322804545.0DomainLDL-receptor class A 15
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892732_27712804545.0DomainLDL-receptor class A 16
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892772_28142804545.0DomainLDL-receptor class A 17
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892816_28552804545.0DomainLDL-receptor class A 18
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892856_28992804545.0DomainLDL-receptor class A 19
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892902_29402804545.0DomainLDL-receptor class A 20
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892941_29812804545.0DomainEGF-like 11
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892982_30222804545.0DomainEGF-like 12%3B calcium-binding
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893290_33312804545.0DomainEGF-like 13
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893332_33712804545.0DomainLDL-receptor class A 21
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893372_34102804545.0DomainLDL-receptor class A 22
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893411_34502804545.0DomainLDL-receptor class A 23
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893451_34912804545.0DomainLDL-receptor class A 24
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893492_35332804545.0DomainLDL-receptor class A 25
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893534_35722804545.0DomainLDL-receptor class A 26
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893573_36112804545.0DomainLDL-receptor class A 27
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893611_36492804545.0DomainLDL-receptor class A 28
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893652_36922804545.0DomainLDL-receptor class A 29
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893693_37332804545.0DomainLDL-receptor class A 30
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893739_37782804545.0DomainLDL-receptor class A 31
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893781_38232804545.0DomainEGF-like 14
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893824_38612804545.0DomainEGF-like 15
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894147_41832804545.0DomainEGF-like 16
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894196_42322804545.0DomainEGF-like 17
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894232_42682804545.0DomainEGF-like 18
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894268_43042804545.0DomainEGF-like 19
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894304_43402804545.0DomainEGF-like 20
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894340_43752804545.0DomainEGF-like 21
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894373_44092804545.0DomainEGF-like 22
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689474_5202804545.0DomainEGF-like 3
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689803_8432804545.0DomainEGF-like 4
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689852_8922804545.0DomainLDL-receptor class A 3
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689893_9332804545.0DomainLDL-receptor class A 4
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689934_9732804545.0DomainLDL-receptor class A 5
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689974_10132804545.0DomainLDL-receptor class A 6
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893940_39432804545.0MotifRecognition site for proteolytical processing
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894502_45072804545.0MotifNote=NPXY motif
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891309_13552804545.0RepeatNote=LDL-receptor class B 8
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891356_13982804545.0RepeatNote=LDL-receptor class B 9
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891399_14452804545.0RepeatNote=LDL-receptor class B 10
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891446_14902804545.0RepeatNote=LDL-receptor class B 11
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891491_15312804545.0RepeatNote=LDL-receptor class B 12
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891627_16692804545.0RepeatNote=LDL-receptor class B 13
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891670_17132804545.0RepeatNote=LDL-receptor class B 14
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891714_17532804545.0RepeatNote=LDL-receptor class B 15
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891754_17982804545.0RepeatNote=LDL-receptor class B 16
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891934_19762804545.0RepeatNote=LDL-receptor class B 17
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6891977_20192804545.0RepeatNote=LDL-receptor class B 18
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892020_20632804545.0RepeatNote=LDL-receptor class B 19
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892064_21072804545.0RepeatNote=LDL-receptor class B 20
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892253_22942804545.0RepeatNote=LDL-receptor class B 21
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892295_23432804545.0RepeatNote=LDL-receptor class B 22
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892344_23882804545.0RepeatNote=LDL-receptor class B 23
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892389_24312804545.0RepeatNote=LDL-receptor class B 24
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6892432_24732804545.0RepeatNote=LDL-receptor class B 25
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689292_3342804545.0RepeatNote=LDL-receptor class B 1
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893069_31132804545.0RepeatNote=LDL-receptor class B 26
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893114_31562804545.0RepeatNote=LDL-receptor class B 27
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893157_32002804545.0RepeatNote=LDL-receptor class B 28
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893201_32432804545.0RepeatNote=LDL-receptor class B 29
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893244_32842804545.0RepeatNote=LDL-receptor class B 30
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689335_3782804545.0RepeatNote=LDL-receptor class B 2
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689379_4222804545.0RepeatNote=LDL-receptor class B 3
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893912_39542804545.0RepeatNote=LDL-receptor class B 31
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6893970_40122804545.0RepeatNote=LDL-receptor class B 32
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894013_40562804545.0RepeatNote=LDL-receptor class B 33
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894057_41012804545.0RepeatNote=LDL-receptor class B 34
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689571_6132804545.0RepeatNote=LDL-receptor class B 4
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689614_6592804545.0RepeatNote=LDL-receptor class B 5
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689660_7102804545.0RepeatNote=LDL-receptor class B 6
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+689711_7542804545.0RepeatNote=LDL-receptor class B 7
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+68920_44192804545.0Topological domainExtracellular
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894420_44442804545.0TransmembraneHelical
TgeneETV6chr12:57539273chr12:12037379ENST000003963734840_124336453.0DomainPNT


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Fusion Gene Sequence for LRP1-ETV6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>49742_49742_1_LRP1-ETV6_LRP1_chr12_57539273_ENST00000243077_ETV6_chr12_12037379_ENST00000396373_length(transcript)=6013nt_BP=1307nt
CAGCGGTGCGAGCTCCAGGCCCATGCACTGAGGAGGCGGAAACAAGGGGAGCCCCCAGAGCTCCATCAAGCCCCCTCCAAAGGCTCCCCT
ACCCGGTCCACGCCCCCCACCCCCCCTCCCCGCCTCCTCCCAATTGTGCATTTTTGCAGCCGGAGGCGGCTCCGAGATGGGGCTGTGAGC
TTCGCCCGGGGAGGGGGAAAGAGCAGCGAGGAGTGAAGCGGGGGGGTGGGGTGAAGGGTTTGGATTTCGGGGCAGGGGGCGCACCCCCGT
CAGCAGGCCCTCCCCAAGGGGCTCGGAACTCTACCTCTTCACCCACGCCCCTGGTGCGCTTTGCCGAAGGAAAGAATAAGAACAGAGAAG
GAGGAGGGGGAAAGGAGGAAAAGGGGGACCCCCCAACTGGGGGGGGTGAAGGAGAGAAGTAGCAGGACCAGAGGGGAAGGGGCTGCTGCT
TGCATCAGCCCACACCATGCTGACCCCGCCGTTGCTCCTGCTGCTGCCCCTGCTCTCAGCTCTGGTCGCGGCGGCTATCGACGCCCCTAA
GACTTGCAGCCCCAAGCAGTTTGCCTGCAGAGATCAAATAACCTGTATCTCAAAGGGCTGGCGGTGCGACGGTGAGAGGGACTGCCCAGA
CGGATCTGACGAGGCCCCTGAGATTTGTCCACAGAGTAAGGCCCAGCGATGCCAGCCAAACGAGCATAACTGCCTGGGTACTGAGCTGTG
TGTTCCCATGTCCCGCCTCTGCAATGGGGTCCAGGACTGCATGGACGGCTCAGATGAGGGGCCCCACTGCCGAGAGCTCCAAGGCAACTG
CTCTCGCCTGGGCTGCCAGCACCATTGTGTCCCCACACTCGATGGGCCCACCTGCTACTGCAACAGCAGCTTTCAGCTTCAGGCAGATGG
CAAGACCTGCAAAGATTTTGATGAGTGCTCAGTGTACGGCACCTGCAGCCAGCTATGCACCAACACAGACGGCTCCTTCATATGTGGCTG
TGTTGAAGGATACCTCCTGCAGCCGGATAACCGCTCCTGCAAGGCCAAGAACGAGCCAGTAGACCGGCCCCCTGTGCTGTTGATAGCCAA
CTCCCAGAACATCTTGGCCACGTACCTGAGTGGGGCCCAGGTGTCTACCATCACACCTACGAGCACGCGGCAGACCACAGCCATGGACTT
CAGCTATGCCAACGAGACCGTATGCTGGGTGCATGTTGGGGACAGTGCTGCTCAGACGCAGCTCAAGTGTGCCCGCATGCCTGGCCTAAA
GGGCTTCGTGGATGAGCACACCATCAACATCTCCCTCAGTCTGCACCACTGTAGACTGCTTTGGGATTACGTCTATCAGTTGCTTTCTGA
CAGCCGGTACGAAAACTTCATCCGATGGGAGGACAAAGAATCCAAAATATTCCGGATAGTGGATCCCAACGGACTGGCTCGACTGTGGGG
AAACCATAAGAACAGAACAAACATGACCTATGAGAAAATGTCCAGAGCCCTGCGCCACTACTACAAACTAAACATTATCAGGAAGGAGCC
AGGACAAAGGCTTTTGTTCAGGTTTATGAAAACCCCAGATGAAATCATGAGTGGCCGAACAGACCGTCTGGAGCACCTAGAGTCCCAGGA
GCTGGATGAACAAATATACCAAGAAGATGAATGCTGAAGGAACCAACAGTCCACCTCAGCGGGCCAGCAGCCCAGGGAACCCCTGCCCAC
CAGGATTGCTGGAAGTGTGACGGAGCAGGCGGGCTGAGGAGAGTGGAAAAGGAAGCGACCCAGAAATGGCAGGGACACTTCTCTTGCAGA
CCAAGAGGGACCCTGGAGCACCTTAGACAAACTACCCAGCACAGGCGGGGCTGGAATTCTGGCGGAGGGCATGAGCCTGGGACTCCATGT
CACGTTTCCTTCTGATTTGGAATCTCTCCATCTGTAATTCCTCACCCTCACCCTTCCACCGTTGTTAGTATCATGGTGTTTTTGTTTTTG
TTTTTGTTTTAAGAACCTGCAGTTTGACTCTTCATCGTTCATCTAGGGGAAGACATCTGATGTTGTTTTCCTATGGAAATATATATCTAT
TATATATATATTTTTTGCAAATCTCACAAAGTGCGGCAAGCCCAGCTGGTCAGGAAAGAGAATACTTGCAGAGGGGTTCAGGTTCCTCTT
TTTCCTGCCACGTGGATCAGGTCTGTTCCTGTTACTGTTGGGTCTTGGCTGAAAAAAAAAAATGCTTTTAAAAAAGATAAAATGAAAAGG
AGAGCTCTCTTTTTCTCTCTCTTGCTCTGTTCTTCCCTTGGTCCCCTCTGTCCTCCCGCCCTGCCTGCAGTTGAGATTCAGATGCCTTCT
GACAGAGTTCAGCCTCTTGGAGAGTCTTGGGGATTGTTGGCACCTAAACAGAATCAGTGACCCGGGTGCTTTGTGGCCAGCAGCACAGAA
TCAAACCCGCATCCCAGCATTGGGCCACCCATCTGAGGGAGGCCAAAATCATCACAGATGCTGCTGTGCTGCAGACAGATACATGCTAGT
CCAGAGAGCCGCCCCTGAGATGGCTGTGAGAACCATGTGTCTAAGGCGTAAGATAAGGATGGAAGGCTGTCCAAGTTATTTGGAAGGCCT
CGGCAGCTTGGGATTAGCTTGGGAGCGCAGCGCTGCAAAGTGGAAAATATGAAAAGACCACACAGGCCCAGCAGTCCAGAAACTGGGCAA
AAATATTCTGCAGTGGGGATTTATTTTTCCAAAGCAGGTAACAGAGGCTAGTGAGAAAGAAAAGCTCCTCTCTGCTCCATTCCAAAGGCC
ATCTTGTGGTCAGTTTCATGCCCTCACCTGATTTTTTTTTTTTTTTTTTTTTTTCAATTCCTAACCTTTTTTAAAGTTTCCTGGTCTCCA
CTGGACACAGAGCTTTGGAGACGGAGGATCCCAGAGGGCAGTCTCAGTTGCAATCAGTGTGTGCCCAGCCTGGGCAGACAGGAAATTCCT
CGGATACATTATTTTTTCTTTCTTTCATAGCTGTGTCTCAGAAAGGACCCATTTGTGGCTCTTTTTCACCTCAAAATAAGATCGATGGTA
TCTTGTAAAATGAGGGTAGTGCCACTTCTTAGTATTTTTGAAAGCTGTTTTAGATTTTTTTTTTTTTTCCTTTTCTAGCCATCTAAATTG
ACTCTTCCAATATAGGTCTCAGAAATCCAATATTTGGAGTACAATTTCTTTTAATCCAGATTACACCTGCCTTACAAAGCACCCCCTCCT
TGTTCCCCTCTGTTTCCTCTACTCAGTTGGGGGAGAAACTCACAGCTCCTCCGGGATACATATGTGCCCTCAGCAGCAGCTCCCAGGTGA
AGTTACCAGACCCCTGGGCTTCTCCCCAGCTTTTTCTGAGTTGAGTCAGACATGTAGAGTTTGGGTCACACAGGCAAGAGGAATTTTCCC
TCGGCCTTACTGACAAGGACACCAACCTAGGGTGCAAACAGATGGACTATGGTTCAAGGACACTGGAATTGAGGAGCTGATCAAGGCTCT
CTTCAGCCTTGCTCTGTCCCTGCCTCTTATCAGAGCACAGGTAGACACACGGGCATAGCCAGCCCACTCCTACTGTCACAGGCGCCCCAC
CATTCAACCTTCCGGGAGGTCAGGGACCTTCTATATGAGGCGAGTGGGTCTCAGTCTGCTTGAATGGTGATGAGATTCTGCTGGATCTCA
GCACGCTGCAGGTGTCTTTTGAGAGCATTCAGTAGGACATGGTGATCCCTATTTCAGCCTCTAAGATGACTGGTATTCTATCTGAAATGC
AGAGATTAAGCCAAATACCTGATGTATTGTGAAAGCCACTGATTTTAAGAATGGAGAGAAAGGGATTTTTTACTGCATCCCTCTGTATGA
ATATGAAATCAGAGACCAGGGCATGATGTTGCTAGGATTAGAGCCTCTCAGTCTGGCCTCTTCACCCAAGTGCAAGAACTCAGTCTCTTA
CTGTTCAAAGAATCTTAACAGTTGAATTATGGAGGGAAATTCCCTTTTGCCCCAAGCATTTCTATATTTAAAGCAATATCCCAGGAGAAT
ATGTTAGACTTAGGATGATACCTTCAGCCACTTGAAGAAGAAATAGAAGGCGCTCATTCCAATATAGTCTTTATTTCCCATTCAGATACA
GGTTGAGCATCCCTAATCTGAACAGTTAAAACCCCCAAATGCCCCAAAATCCAAACCTTCCTGAACGCTATGACACCATGAGTGGAAAAT
TCCACACCTAACAAACACATTTGCTTTCTTATGGTTCAATGTACACAAACTGTTTTATATAGAAAATGATTTCAAATATCATAAAATTAC
CTTCAGGCTATGTGTATAAAGTATATATGAGCCATAAATGAATTTTGTGTTTAGACTTTGTGTCCATCCCCAAGATCTCTCATTTTATAT
ATATATATATATATATATATATATATATATATATATATATATACACACACACACACATACACAAATATTCCAGGATACAAAAAAAAACAT
TTAAAAATCCGAGACCCAGAACACTTCTGGTCCCAAGCATTTCAGATAAGGGATATCAATCTGTACTACCAATAAGGATTTCGTAATTCC
CCTAACTGCAAATGTCCTCTTCATTTGTTCTTTATGAGAAAACCCGGGTAGTGCCAGCACCTGGATACAGTATTTACACCCTGCAGACCC
TAAAGATTTCAGATTCAGTTAGCAAACCTTGATGAAGCACCTGCTGGACACTGAGGGACCCAAAGCTCAATCAGCCATAATCCCTGCTTT
CAGAGTTTATATTGTACCTGCCTAATCCACCCGGCGTGACTCATTTCAACACTAAGTACTAGGGGTGTTGTCAGGAGACAAATCTGAAGT
CAGGAGAGGAAAATGCAAAGGAGCCCTGCCGTGTGATGGATGTGCATTCTCACTTGGGTCTTGAAGTTCTCATTCCTACATCTCAAGCTA
GCCAGGCAGTCTCCTCTCTATCAGAAGAAAGCACTGGTAATTGGCTAGACTGGCTATGTTGAAGGTAACATGAACTCTAAGATCTTGACC
CAGGGCGACTTGGTTTTGCTTAAGGTGGCATCACCAATGTTCCAAATCCTTTAGGGAGATGAGGGTATCCCCACAGAAAAAGAGGAATAA
TAGACCAATGGATTTTCTCCTTTCACCAGTATGTTTGGAACCCTCTGATCCAATGTCTTTTGATACTGATCTCTTGTCCAAATGAGAATG
TCGCTTTAGCTGAAATTCAAATGGCTGTGACAATTTACCGAAATGATGAAGTAACCACCATTCCCACCTTTCACTGCCTAGGCTCCAAGT
CTGAATACATTTTTGAAATAGGAACTCCCTTTTGCAAAAAAGAAACCTGGGTGTCAGGGAGGTGAAGTGACTTGCCCTAGGAGCAGACAG
CATGCCAAGAATGGAATTAGGCTCAGGATCCAGCCTGGGCTCACCCTGTGTGGCTCATTCCCACCCAGGAAACTGAAGATAAAAGATTTG
GGAAAACACACCAAGAAAAAGGGGCAGTTTTCTTTGCCCAAGCATTTGGTGCTAGTTAGAGGCTGTTCACTCTCTCCTGCTCCTCTTCGG
AGTAGAAATAAAGGCTGTGACACAAGGAAGCCAGTGGGGTGGGAGGGAGGCACCATAATCCCTCCCTAAAACCCACAGAAGACTAACCTG
ATACTCTTTTGACCCAACTGCATCAACACTAAACAGCTGCAGACCCCCTGAATCTTTCACACATGCCAAGTGAACATTCTTGATGATTTC
TCTTTGTGACCGCAACCACCTGCAAACCAGAACGACTCTAGAATTTCCTTCCCCGCCCCCCTTTTTGTTTAGTTTCTAATCTCTTGTTTA
TGAGGTGTGGGGTTTATAAGGGACTGAATCAAATGAATGTAACAAAAAAGAAAAAAAAAACAAAAAAAAATGCCTTTTCTCAGGGCCAGT

>49742_49742_1_LRP1-ETV6_LRP1_chr12_57539273_ENST00000243077_ETV6_chr12_12037379_ENST00000396373_length(amino acids)=404AA_BP=289
MLLASAHTMLTPPLLLLLPLLSALVAAAIDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGT
ELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFI
CGCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMP
GLKGFVDEHTINISLSLHHCRLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIR

--------------------------------------------------------------
>49742_49742_2_LRP1-ETV6_LRP1_chr12_57539273_ENST00000338962_ETV6_chr12_12037379_ENST00000396373_length(transcript)=5796nt_BP=1090nt
GCGGGGGGGTGGGGTGAAGGGTTTGGATTTCGGGGCAGGGGGCGCACCCCCGTCAGCAGGCCCTCCCCAAGGGGCTCGGAACTCTACCTC
TTCACCCACGCCCCTGGTGCGCTTTGCCGAAGGAAAGAATAAGAACAGAGAAGGAGGAGGGGGAAAGGAGGAAAAGGGGGACCCCCCAAC
TGGGGGGGGTGAAGGAGAGAAGTAGCAGGACCAGAGGGGAAGGGGCTGCTGCTTGCATCAGCCCACACCATGCTGACCCCGCCGTTGCTC
CTGCTGCTGCCCCTGCTCTCAGCTCTGGTCGCGGCGGCTATCGACGCCCCTAAGACTTGCAGCCCCAAGCAGTTTGCCTGCAGAGATCAA
ATAACCTGTATCTCAAAGGGCTGGCGGTGCGACGGTGAGAGGGACTGCCCAGACGGATCTGACGAGGCCCCTGAGATTTGTCCACAGAGT
AAGGCCCAGCGATGCCAGCCAAACGAGCATAACTGCCTGGGTACTGAGCTGTGTGTTCCCATGTCCCGCCTCTGCAATGGGGTCCAGGAC
TGCATGGACGGCTCAGATGAGGGGCCCCACTGCCGAGAGCTCCAAGGCAACTGCTCTCGCCTGGGCTGCCAGCACCATTGTGTCCCCACA
CTCGATGGGCCCACCTGCTACTGCAACAGCAGCTTTCAGCTTCAGGCAGATGGCAAGACCTGCAAAGATTTTGATGAGTGCTCAGTGTAC
GGCACCTGCAGCCAGCTATGCACCAACACAGACGGCTCCTTCATATGTGGCTGTGTTGAAGGATACCTCCTGCAGCCGGATAACCGCTCC
TGCAAGGCCAAGAACGAGCCAGTAGACCGGCCCCCTGTGCTGTTGATAGCCAACTCCCAGAACATCTTGGCCACGTACCTGAGTGGGGCC
CAGGTGTCTACCATCACACCTACGAGCACGCGGCAGACCACAGCCATGGACTTCAGCTATGCCAACGAGACCGTATGCTGGGTGCATGTT
GGGGACAGTGCTGCTCAGACGCAGCTCAAGTGTGCCCGCATGCCTGGCCTAAAGGGCTTCGTGGATGAGCACACCATCAACATCTCCCTC
AGTCTGCACCACTGTAGACTGCTTTGGGATTACGTCTATCAGTTGCTTTCTGACAGCCGGTACGAAAACTTCATCCGATGGGAGGACAAA
GAATCCAAAATATTCCGGATAGTGGATCCCAACGGACTGGCTCGACTGTGGGGAAACCATAAGAACAGAACAAACATGACCTATGAGAAA
ATGTCCAGAGCCCTGCGCCACTACTACAAACTAAACATTATCAGGAAGGAGCCAGGACAAAGGCTTTTGTTCAGGTTTATGAAAACCCCA
GATGAAATCATGAGTGGCCGAACAGACCGTCTGGAGCACCTAGAGTCCCAGGAGCTGGATGAACAAATATACCAAGAAGATGAATGCTGA
AGGAACCAACAGTCCACCTCAGCGGGCCAGCAGCCCAGGGAACCCCTGCCCACCAGGATTGCTGGAAGTGTGACGGAGCAGGCGGGCTGA
GGAGAGTGGAAAAGGAAGCGACCCAGAAATGGCAGGGACACTTCTCTTGCAGACCAAGAGGGACCCTGGAGCACCTTAGACAAACTACCC
AGCACAGGCGGGGCTGGAATTCTGGCGGAGGGCATGAGCCTGGGACTCCATGTCACGTTTCCTTCTGATTTGGAATCTCTCCATCTGTAA
TTCCTCACCCTCACCCTTCCACCGTTGTTAGTATCATGGTGTTTTTGTTTTTGTTTTTGTTTTAAGAACCTGCAGTTTGACTCTTCATCG
TTCATCTAGGGGAAGACATCTGATGTTGTTTTCCTATGGAAATATATATCTATTATATATATATTTTTTGCAAATCTCACAAAGTGCGGC
AAGCCCAGCTGGTCAGGAAAGAGAATACTTGCAGAGGGGTTCAGGTTCCTCTTTTTCCTGCCACGTGGATCAGGTCTGTTCCTGTTACTG
TTGGGTCTTGGCTGAAAAAAAAAAATGCTTTTAAAAAAGATAAAATGAAAAGGAGAGCTCTCTTTTTCTCTCTCTTGCTCTGTTCTTCCC
TTGGTCCCCTCTGTCCTCCCGCCCTGCCTGCAGTTGAGATTCAGATGCCTTCTGACAGAGTTCAGCCTCTTGGAGAGTCTTGGGGATTGT
TGGCACCTAAACAGAATCAGTGACCCGGGTGCTTTGTGGCCAGCAGCACAGAATCAAACCCGCATCCCAGCATTGGGCCACCCATCTGAG
GGAGGCCAAAATCATCACAGATGCTGCTGTGCTGCAGACAGATACATGCTAGTCCAGAGAGCCGCCCCTGAGATGGCTGTGAGAACCATG
TGTCTAAGGCGTAAGATAAGGATGGAAGGCTGTCCAAGTTATTTGGAAGGCCTCGGCAGCTTGGGATTAGCTTGGGAGCGCAGCGCTGCA
AAGTGGAAAATATGAAAAGACCACACAGGCCCAGCAGTCCAGAAACTGGGCAAAAATATTCTGCAGTGGGGATTTATTTTTCCAAAGCAG
GTAACAGAGGCTAGTGAGAAAGAAAAGCTCCTCTCTGCTCCATTCCAAAGGCCATCTTGTGGTCAGTTTCATGCCCTCACCTGATTTTTT
TTTTTTTTTTTTTTTTTCAATTCCTAACCTTTTTTAAAGTTTCCTGGTCTCCACTGGACACAGAGCTTTGGAGACGGAGGATCCCAGAGG
GCAGTCTCAGTTGCAATCAGTGTGTGCCCAGCCTGGGCAGACAGGAAATTCCTCGGATACATTATTTTTTCTTTCTTTCATAGCTGTGTC
TCAGAAAGGACCCATTTGTGGCTCTTTTTCACCTCAAAATAAGATCGATGGTATCTTGTAAAATGAGGGTAGTGCCACTTCTTAGTATTT
TTGAAAGCTGTTTTAGATTTTTTTTTTTTTTCCTTTTCTAGCCATCTAAATTGACTCTTCCAATATAGGTCTCAGAAATCCAATATTTGG
AGTACAATTTCTTTTAATCCAGATTACACCTGCCTTACAAAGCACCCCCTCCTTGTTCCCCTCTGTTTCCTCTACTCAGTTGGGGGAGAA
ACTCACAGCTCCTCCGGGATACATATGTGCCCTCAGCAGCAGCTCCCAGGTGAAGTTACCAGACCCCTGGGCTTCTCCCCAGCTTTTTCT
GAGTTGAGTCAGACATGTAGAGTTTGGGTCACACAGGCAAGAGGAATTTTCCCTCGGCCTTACTGACAAGGACACCAACCTAGGGTGCAA
ACAGATGGACTATGGTTCAAGGACACTGGAATTGAGGAGCTGATCAAGGCTCTCTTCAGCCTTGCTCTGTCCCTGCCTCTTATCAGAGCA
CAGGTAGACACACGGGCATAGCCAGCCCACTCCTACTGTCACAGGCGCCCCACCATTCAACCTTCCGGGAGGTCAGGGACCTTCTATATG
AGGCGAGTGGGTCTCAGTCTGCTTGAATGGTGATGAGATTCTGCTGGATCTCAGCACGCTGCAGGTGTCTTTTGAGAGCATTCAGTAGGA
CATGGTGATCCCTATTTCAGCCTCTAAGATGACTGGTATTCTATCTGAAATGCAGAGATTAAGCCAAATACCTGATGTATTGTGAAAGCC
ACTGATTTTAAGAATGGAGAGAAAGGGATTTTTTACTGCATCCCTCTGTATGAATATGAAATCAGAGACCAGGGCATGATGTTGCTAGGA
TTAGAGCCTCTCAGTCTGGCCTCTTCACCCAAGTGCAAGAACTCAGTCTCTTACTGTTCAAAGAATCTTAACAGTTGAATTATGGAGGGA
AATTCCCTTTTGCCCCAAGCATTTCTATATTTAAAGCAATATCCCAGGAGAATATGTTAGACTTAGGATGATACCTTCAGCCACTTGAAG
AAGAAATAGAAGGCGCTCATTCCAATATAGTCTTTATTTCCCATTCAGATACAGGTTGAGCATCCCTAATCTGAACAGTTAAAACCCCCA
AATGCCCCAAAATCCAAACCTTCCTGAACGCTATGACACCATGAGTGGAAAATTCCACACCTAACAAACACATTTGCTTTCTTATGGTTC
AATGTACACAAACTGTTTTATATAGAAAATGATTTCAAATATCATAAAATTACCTTCAGGCTATGTGTATAAAGTATATATGAGCCATAA
ATGAATTTTGTGTTTAGACTTTGTGTCCATCCCCAAGATCTCTCATTTTATATATATATATATATATATATATATATATATATATATATA
TATATACACACACACACACATACACAAATATTCCAGGATACAAAAAAAAACATTTAAAAATCCGAGACCCAGAACACTTCTGGTCCCAAG
CATTTCAGATAAGGGATATCAATCTGTACTACCAATAAGGATTTCGTAATTCCCCTAACTGCAAATGTCCTCTTCATTTGTTCTTTATGA
GAAAACCCGGGTAGTGCCAGCACCTGGATACAGTATTTACACCCTGCAGACCCTAAAGATTTCAGATTCAGTTAGCAAACCTTGATGAAG
CACCTGCTGGACACTGAGGGACCCAAAGCTCAATCAGCCATAATCCCTGCTTTCAGAGTTTATATTGTACCTGCCTAATCCACCCGGCGT
GACTCATTTCAACACTAAGTACTAGGGGTGTTGTCAGGAGACAAATCTGAAGTCAGGAGAGGAAAATGCAAAGGAGCCCTGCCGTGTGAT
GGATGTGCATTCTCACTTGGGTCTTGAAGTTCTCATTCCTACATCTCAAGCTAGCCAGGCAGTCTCCTCTCTATCAGAAGAAAGCACTGG
TAATTGGCTAGACTGGCTATGTTGAAGGTAACATGAACTCTAAGATCTTGACCCAGGGCGACTTGGTTTTGCTTAAGGTGGCATCACCAA
TGTTCCAAATCCTTTAGGGAGATGAGGGTATCCCCACAGAAAAAGAGGAATAATAGACCAATGGATTTTCTCCTTTCACCAGTATGTTTG
GAACCCTCTGATCCAATGTCTTTTGATACTGATCTCTTGTCCAAATGAGAATGTCGCTTTAGCTGAAATTCAAATGGCTGTGACAATTTA
CCGAAATGATGAAGTAACCACCATTCCCACCTTTCACTGCCTAGGCTCCAAGTCTGAATACATTTTTGAAATAGGAACTCCCTTTTGCAA
AAAAGAAACCTGGGTGTCAGGGAGGTGAAGTGACTTGCCCTAGGAGCAGACAGCATGCCAAGAATGGAATTAGGCTCAGGATCCAGCCTG
GGCTCACCCTGTGTGGCTCATTCCCACCCAGGAAACTGAAGATAAAAGATTTGGGAAAACACACCAAGAAAAAGGGGCAGTTTTCTTTGC
CCAAGCATTTGGTGCTAGTTAGAGGCTGTTCACTCTCTCCTGCTCCTCTTCGGAGTAGAAATAAAGGCTGTGACACAAGGAAGCCAGTGG
GGTGGGAGGGAGGCACCATAATCCCTCCCTAAAACCCACAGAAGACTAACCTGATACTCTTTTGACCCAACTGCATCAACACTAAACAGC
TGCAGACCCCCTGAATCTTTCACACATGCCAAGTGAACATTCTTGATGATTTCTCTTTGTGACCGCAACCACCTGCAAACCAGAACGACT
CTAGAATTTCCTTCCCCGCCCCCCTTTTTGTTTAGTTTCTAATCTCTTGTTTATGAGGTGTGGGGTTTATAAGGGACTGAATCAAATGAA
TGTAACAAAAAAGAAAAAAAAAACAAAAAAAAATGCCTTTTCTCAGGGCCAGTGAGTTGCAAATAATTTTTAAAGAAAAGCCTATAATTA

>49742_49742_2_LRP1-ETV6_LRP1_chr12_57539273_ENST00000338962_ETV6_chr12_12037379_ENST00000396373_length(amino acids)=404AA_BP=289
MLLASAHTMLTPPLLLLLPLLSALVAAAIDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGT
ELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFI
CGCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMP
GLKGFVDEHTINISLSLHHCRLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIR

--------------------------------------------------------------
>49742_49742_3_LRP1-ETV6_LRP1_chr12_57539273_ENST00000553277_ETV6_chr12_12037379_ENST00000396373_length(transcript)=6019nt_BP=1313nt
GGGGAACAGCGGTGCGAGCTCCAGGCCCATGCACTGAGGAGGCGGAAACAAGGGGAGCCCCCAGAGCTCCATCAAGCCCCCTCCAAAGGC
TCCCCTACCCGGTCCACGCCCCCCACCCCCCCTCCCCGCCTCCTCCCAATTGTGCATTTTTGCAGCCGGAGGCGGCTCCGAGATGGGGCT
GTGAGCTTCGCCCGGGGAGGGGGAAAGAGCAGCGAGGAGTGAAGCGGGGGGGTGGGGTGAAGGGTTTGGATTTCGGGGCAGGGGGCGCAC
CCCCGTCAGCAGGCCCTCCCCAAGGGGCTCGGAACTCTACCTCTTCACCCACGCCCCTGGTGCGCTTTGCCGAAGGAAAGAATAAGAACA
GAGAAGGAGGAGGGGGAAAGGAGGAAAAGGGGGACCCCCCAACTGGGGGGGGTGAAGGAGAGAAGTAGCAGGACCAGAGGGGAAGGGGCT
GCTGCTTGCATCAGCCCACACCATGCTGACCCCGCCGTTGCTCCTGCTGCTGCCCCTGCTCTCAGCTCTGGTCGCGGCGGCTATCGACGC
CCCTAAGACTTGCAGCCCCAAGCAGTTTGCCTGCAGAGATCAAATAACCTGTATCTCAAAGGGCTGGCGGTGCGACGGTGAGAGGGACTG
CCCAGACGGATCTGACGAGGCCCCTGAGATTTGTCCACAGAGTAAGGCCCAGCGATGCCAGCCAAACGAGCATAACTGCCTGGGTACTGA
GCTGTGTGTTCCCATGTCCCGCCTCTGCAATGGGGTCCAGGACTGCATGGACGGCTCAGATGAGGGGCCCCACTGCCGAGAGCTCCAAGG
CAACTGCTCTCGCCTGGGCTGCCAGCACCATTGTGTCCCCACACTCGATGGGCCCACCTGCTACTGCAACAGCAGCTTTCAGCTTCAGGC
AGATGGCAAGACCTGCAAAGATTTTGATGAGTGCTCAGTGTACGGCACCTGCAGCCAGCTATGCACCAACACAGACGGCTCCTTCATATG
TGGCTGTGTTGAAGGATACCTCCTGCAGCCGGATAACCGCTCCTGCAAGGCCAAGAACGAGCCAGTAGACCGGCCCCCTGTGCTGTTGAT
AGCCAACTCCCAGAACATCTTGGCCACGTACCTGAGTGGGGCCCAGGTGTCTACCATCACACCTACGAGCACGCGGCAGACCACAGCCAT
GGACTTCAGCTATGCCAACGAGACCGTATGCTGGGTGCATGTTGGGGACAGTGCTGCTCAGACGCAGCTCAAGTGTGCCCGCATGCCTGG
CCTAAAGGGCTTCGTGGATGAGCACACCATCAACATCTCCCTCAGTCTGCACCACTGTAGACTGCTTTGGGATTACGTCTATCAGTTGCT
TTCTGACAGCCGGTACGAAAACTTCATCCGATGGGAGGACAAAGAATCCAAAATATTCCGGATAGTGGATCCCAACGGACTGGCTCGACT
GTGGGGAAACCATAAGAACAGAACAAACATGACCTATGAGAAAATGTCCAGAGCCCTGCGCCACTACTACAAACTAAACATTATCAGGAA
GGAGCCAGGACAAAGGCTTTTGTTCAGGTTTATGAAAACCCCAGATGAAATCATGAGTGGCCGAACAGACCGTCTGGAGCACCTAGAGTC
CCAGGAGCTGGATGAACAAATATACCAAGAAGATGAATGCTGAAGGAACCAACAGTCCACCTCAGCGGGCCAGCAGCCCAGGGAACCCCT
GCCCACCAGGATTGCTGGAAGTGTGACGGAGCAGGCGGGCTGAGGAGAGTGGAAAAGGAAGCGACCCAGAAATGGCAGGGACACTTCTCT
TGCAGACCAAGAGGGACCCTGGAGCACCTTAGACAAACTACCCAGCACAGGCGGGGCTGGAATTCTGGCGGAGGGCATGAGCCTGGGACT
CCATGTCACGTTTCCTTCTGATTTGGAATCTCTCCATCTGTAATTCCTCACCCTCACCCTTCCACCGTTGTTAGTATCATGGTGTTTTTG
TTTTTGTTTTTGTTTTAAGAACCTGCAGTTTGACTCTTCATCGTTCATCTAGGGGAAGACATCTGATGTTGTTTTCCTATGGAAATATAT
ATCTATTATATATATATTTTTTGCAAATCTCACAAAGTGCGGCAAGCCCAGCTGGTCAGGAAAGAGAATACTTGCAGAGGGGTTCAGGTT
CCTCTTTTTCCTGCCACGTGGATCAGGTCTGTTCCTGTTACTGTTGGGTCTTGGCTGAAAAAAAAAAATGCTTTTAAAAAAGATAAAATG
AAAAGGAGAGCTCTCTTTTTCTCTCTCTTGCTCTGTTCTTCCCTTGGTCCCCTCTGTCCTCCCGCCCTGCCTGCAGTTGAGATTCAGATG
CCTTCTGACAGAGTTCAGCCTCTTGGAGAGTCTTGGGGATTGTTGGCACCTAAACAGAATCAGTGACCCGGGTGCTTTGTGGCCAGCAGC
ACAGAATCAAACCCGCATCCCAGCATTGGGCCACCCATCTGAGGGAGGCCAAAATCATCACAGATGCTGCTGTGCTGCAGACAGATACAT
GCTAGTCCAGAGAGCCGCCCCTGAGATGGCTGTGAGAACCATGTGTCTAAGGCGTAAGATAAGGATGGAAGGCTGTCCAAGTTATTTGGA
AGGCCTCGGCAGCTTGGGATTAGCTTGGGAGCGCAGCGCTGCAAAGTGGAAAATATGAAAAGACCACACAGGCCCAGCAGTCCAGAAACT
GGGCAAAAATATTCTGCAGTGGGGATTTATTTTTCCAAAGCAGGTAACAGAGGCTAGTGAGAAAGAAAAGCTCCTCTCTGCTCCATTCCA
AAGGCCATCTTGTGGTCAGTTTCATGCCCTCACCTGATTTTTTTTTTTTTTTTTTTTTTTCAATTCCTAACCTTTTTTAAAGTTTCCTGG
TCTCCACTGGACACAGAGCTTTGGAGACGGAGGATCCCAGAGGGCAGTCTCAGTTGCAATCAGTGTGTGCCCAGCCTGGGCAGACAGGAA
ATTCCTCGGATACATTATTTTTTCTTTCTTTCATAGCTGTGTCTCAGAAAGGACCCATTTGTGGCTCTTTTTCACCTCAAAATAAGATCG
ATGGTATCTTGTAAAATGAGGGTAGTGCCACTTCTTAGTATTTTTGAAAGCTGTTTTAGATTTTTTTTTTTTTTCCTTTTCTAGCCATCT
AAATTGACTCTTCCAATATAGGTCTCAGAAATCCAATATTTGGAGTACAATTTCTTTTAATCCAGATTACACCTGCCTTACAAAGCACCC
CCTCCTTGTTCCCCTCTGTTTCCTCTACTCAGTTGGGGGAGAAACTCACAGCTCCTCCGGGATACATATGTGCCCTCAGCAGCAGCTCCC
AGGTGAAGTTACCAGACCCCTGGGCTTCTCCCCAGCTTTTTCTGAGTTGAGTCAGACATGTAGAGTTTGGGTCACACAGGCAAGAGGAAT
TTTCCCTCGGCCTTACTGACAAGGACACCAACCTAGGGTGCAAACAGATGGACTATGGTTCAAGGACACTGGAATTGAGGAGCTGATCAA
GGCTCTCTTCAGCCTTGCTCTGTCCCTGCCTCTTATCAGAGCACAGGTAGACACACGGGCATAGCCAGCCCACTCCTACTGTCACAGGCG
CCCCACCATTCAACCTTCCGGGAGGTCAGGGACCTTCTATATGAGGCGAGTGGGTCTCAGTCTGCTTGAATGGTGATGAGATTCTGCTGG
ATCTCAGCACGCTGCAGGTGTCTTTTGAGAGCATTCAGTAGGACATGGTGATCCCTATTTCAGCCTCTAAGATGACTGGTATTCTATCTG
AAATGCAGAGATTAAGCCAAATACCTGATGTATTGTGAAAGCCACTGATTTTAAGAATGGAGAGAAAGGGATTTTTTACTGCATCCCTCT
GTATGAATATGAAATCAGAGACCAGGGCATGATGTTGCTAGGATTAGAGCCTCTCAGTCTGGCCTCTTCACCCAAGTGCAAGAACTCAGT
CTCTTACTGTTCAAAGAATCTTAACAGTTGAATTATGGAGGGAAATTCCCTTTTGCCCCAAGCATTTCTATATTTAAAGCAATATCCCAG
GAGAATATGTTAGACTTAGGATGATACCTTCAGCCACTTGAAGAAGAAATAGAAGGCGCTCATTCCAATATAGTCTTTATTTCCCATTCA
GATACAGGTTGAGCATCCCTAATCTGAACAGTTAAAACCCCCAAATGCCCCAAAATCCAAACCTTCCTGAACGCTATGACACCATGAGTG
GAAAATTCCACACCTAACAAACACATTTGCTTTCTTATGGTTCAATGTACACAAACTGTTTTATATAGAAAATGATTTCAAATATCATAA
AATTACCTTCAGGCTATGTGTATAAAGTATATATGAGCCATAAATGAATTTTGTGTTTAGACTTTGTGTCCATCCCCAAGATCTCTCATT
TTATATATATATATATATATATATATATATATATATATATATATATATACACACACACACACATACACAAATATTCCAGGATACAAAAAA
AAACATTTAAAAATCCGAGACCCAGAACACTTCTGGTCCCAAGCATTTCAGATAAGGGATATCAATCTGTACTACCAATAAGGATTTCGT
AATTCCCCTAACTGCAAATGTCCTCTTCATTTGTTCTTTATGAGAAAACCCGGGTAGTGCCAGCACCTGGATACAGTATTTACACCCTGC
AGACCCTAAAGATTTCAGATTCAGTTAGCAAACCTTGATGAAGCACCTGCTGGACACTGAGGGACCCAAAGCTCAATCAGCCATAATCCC
TGCTTTCAGAGTTTATATTGTACCTGCCTAATCCACCCGGCGTGACTCATTTCAACACTAAGTACTAGGGGTGTTGTCAGGAGACAAATC
TGAAGTCAGGAGAGGAAAATGCAAAGGAGCCCTGCCGTGTGATGGATGTGCATTCTCACTTGGGTCTTGAAGTTCTCATTCCTACATCTC
AAGCTAGCCAGGCAGTCTCCTCTCTATCAGAAGAAAGCACTGGTAATTGGCTAGACTGGCTATGTTGAAGGTAACATGAACTCTAAGATC
TTGACCCAGGGCGACTTGGTTTTGCTTAAGGTGGCATCACCAATGTTCCAAATCCTTTAGGGAGATGAGGGTATCCCCACAGAAAAAGAG
GAATAATAGACCAATGGATTTTCTCCTTTCACCAGTATGTTTGGAACCCTCTGATCCAATGTCTTTTGATACTGATCTCTTGTCCAAATG
AGAATGTCGCTTTAGCTGAAATTCAAATGGCTGTGACAATTTACCGAAATGATGAAGTAACCACCATTCCCACCTTTCACTGCCTAGGCT
CCAAGTCTGAATACATTTTTGAAATAGGAACTCCCTTTTGCAAAAAAGAAACCTGGGTGTCAGGGAGGTGAAGTGACTTGCCCTAGGAGC
AGACAGCATGCCAAGAATGGAATTAGGCTCAGGATCCAGCCTGGGCTCACCCTGTGTGGCTCATTCCCACCCAGGAAACTGAAGATAAAA
GATTTGGGAAAACACACCAAGAAAAAGGGGCAGTTTTCTTTGCCCAAGCATTTGGTGCTAGTTAGAGGCTGTTCACTCTCTCCTGCTCCT
CTTCGGAGTAGAAATAAAGGCTGTGACACAAGGAAGCCAGTGGGGTGGGAGGGAGGCACCATAATCCCTCCCTAAAACCCACAGAAGACT
AACCTGATACTCTTTTGACCCAACTGCATCAACACTAAACAGCTGCAGACCCCCTGAATCTTTCACACATGCCAAGTGAACATTCTTGAT
GATTTCTCTTTGTGACCGCAACCACCTGCAAACCAGAACGACTCTAGAATTTCCTTCCCCGCCCCCCTTTTTGTTTAGTTTCTAATCTCT
TGTTTATGAGGTGTGGGGTTTATAAGGGACTGAATCAAATGAATGTAACAAAAAAGAAAAAAAAAACAAAAAAAAATGCCTTTTCTCAGG

>49742_49742_3_LRP1-ETV6_LRP1_chr12_57539273_ENST00000553277_ETV6_chr12_12037379_ENST00000396373_length(amino acids)=404AA_BP=289
MLLASAHTMLTPPLLLLLPLLSALVAAAIDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGT
ELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFI
CGCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMP
GLKGFVDEHTINISLSLHHCRLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIR

--------------------------------------------------------------
>49742_49742_4_LRP1-ETV6_LRP1_chr12_57539273_ENST00000554174_ETV6_chr12_12037379_ENST00000396373_length(transcript)=5603nt_BP=897nt
GGAGAGAAGTAGCAGGACCAGAGGGGAAGGGGCTGCTGCTTGCATCAGCCCACACCATGCTGACCCCGCCGTTGCTCCTGCTGCTGCCCC
TGCTCTCAGCTCTGGTCGCGGCGGCTATCGACGCCCCTAAGACTTGCAGCCCCAAGCAGTTTGCCTGCAGAGATCAAATAACCTGTATCT
CAAAGGGCTGGCGGTGCGACGGTGAGAGGGACTGCCCAGACGGATCTGACGAGGCCCCTGAGATTTGTCCACAGAGTAAGGCCCAGCGAT
GCCAGCCAAACGAGCATAACTGCCTGGGTACTGAGCTGTGTGTTCCCATGTCCCGCCTCTGCAATGGGGTCCAGGACTGCATGGACGGCT
CAGATGAGGGGCCCCACTGCCGAGAGCTCCAAGGCAACTGCTCTCGCCTGGGCTGCCAGCACCATTGTGTCCCCACACTCGATGGGCCCA
CCTGCTACTGCAACAGCAGCTTTCAGCTTCAGGCAGATGGCAAGACCTGCAAAGATTTTGATGAGTGCTCAGTGTACGGCACCTGCAGCC
AGCTATGCACCAACACAGACGGCTCCTTCATATGTGGCTGTGTTGAAGGATACCTCCTGCAGCCGGATAACCGCTCCTGCAAGGCCAAGA
ACGAGCCAGTAGACCGGCCCCCTGTGCTGTTGATAGCCAACTCCCAGAACATCTTGGCCACGTACCTGAGTGGGGCCCAGGTGTCTACCA
TCACACCTACGAGCACGCGGCAGACCACAGCCATGGACTTCAGCTATGCCAACGAGACCGTATGCTGGGTGCATGTTGGGGACAGTGCTG
CTCAGACGCAGCTCAAGTGTGCCCGCATGCCTGGCCTAAAGGGCTTCGTGGATGAGCACACCATCAACATCTCCCTCAGTCTGCACCACT
GTAGACTGCTTTGGGATTACGTCTATCAGTTGCTTTCTGACAGCCGGTACGAAAACTTCATCCGATGGGAGGACAAAGAATCCAAAATAT
TCCGGATAGTGGATCCCAACGGACTGGCTCGACTGTGGGGAAACCATAAGAACAGAACAAACATGACCTATGAGAAAATGTCCAGAGCCC
TGCGCCACTACTACAAACTAAACATTATCAGGAAGGAGCCAGGACAAAGGCTTTTGTTCAGGTTTATGAAAACCCCAGATGAAATCATGA
GTGGCCGAACAGACCGTCTGGAGCACCTAGAGTCCCAGGAGCTGGATGAACAAATATACCAAGAAGATGAATGCTGAAGGAACCAACAGT
CCACCTCAGCGGGCCAGCAGCCCAGGGAACCCCTGCCCACCAGGATTGCTGGAAGTGTGACGGAGCAGGCGGGCTGAGGAGAGTGGAAAA
GGAAGCGACCCAGAAATGGCAGGGACACTTCTCTTGCAGACCAAGAGGGACCCTGGAGCACCTTAGACAAACTACCCAGCACAGGCGGGG
CTGGAATTCTGGCGGAGGGCATGAGCCTGGGACTCCATGTCACGTTTCCTTCTGATTTGGAATCTCTCCATCTGTAATTCCTCACCCTCA
CCCTTCCACCGTTGTTAGTATCATGGTGTTTTTGTTTTTGTTTTTGTTTTAAGAACCTGCAGTTTGACTCTTCATCGTTCATCTAGGGGA
AGACATCTGATGTTGTTTTCCTATGGAAATATATATCTATTATATATATATTTTTTGCAAATCTCACAAAGTGCGGCAAGCCCAGCTGGT
CAGGAAAGAGAATACTTGCAGAGGGGTTCAGGTTCCTCTTTTTCCTGCCACGTGGATCAGGTCTGTTCCTGTTACTGTTGGGTCTTGGCT
GAAAAAAAAAAATGCTTTTAAAAAAGATAAAATGAAAAGGAGAGCTCTCTTTTTCTCTCTCTTGCTCTGTTCTTCCCTTGGTCCCCTCTG
TCCTCCCGCCCTGCCTGCAGTTGAGATTCAGATGCCTTCTGACAGAGTTCAGCCTCTTGGAGAGTCTTGGGGATTGTTGGCACCTAAACA
GAATCAGTGACCCGGGTGCTTTGTGGCCAGCAGCACAGAATCAAACCCGCATCCCAGCATTGGGCCACCCATCTGAGGGAGGCCAAAATC
ATCACAGATGCTGCTGTGCTGCAGACAGATACATGCTAGTCCAGAGAGCCGCCCCTGAGATGGCTGTGAGAACCATGTGTCTAAGGCGTA
AGATAAGGATGGAAGGCTGTCCAAGTTATTTGGAAGGCCTCGGCAGCTTGGGATTAGCTTGGGAGCGCAGCGCTGCAAAGTGGAAAATAT
GAAAAGACCACACAGGCCCAGCAGTCCAGAAACTGGGCAAAAATATTCTGCAGTGGGGATTTATTTTTCCAAAGCAGGTAACAGAGGCTA
GTGAGAAAGAAAAGCTCCTCTCTGCTCCATTCCAAAGGCCATCTTGTGGTCAGTTTCATGCCCTCACCTGATTTTTTTTTTTTTTTTTTT
TTTTCAATTCCTAACCTTTTTTAAAGTTTCCTGGTCTCCACTGGACACAGAGCTTTGGAGACGGAGGATCCCAGAGGGCAGTCTCAGTTG
CAATCAGTGTGTGCCCAGCCTGGGCAGACAGGAAATTCCTCGGATACATTATTTTTTCTTTCTTTCATAGCTGTGTCTCAGAAAGGACCC
ATTTGTGGCTCTTTTTCACCTCAAAATAAGATCGATGGTATCTTGTAAAATGAGGGTAGTGCCACTTCTTAGTATTTTTGAAAGCTGTTT
TAGATTTTTTTTTTTTTTCCTTTTCTAGCCATCTAAATTGACTCTTCCAATATAGGTCTCAGAAATCCAATATTTGGAGTACAATTTCTT
TTAATCCAGATTACACCTGCCTTACAAAGCACCCCCTCCTTGTTCCCCTCTGTTTCCTCTACTCAGTTGGGGGAGAAACTCACAGCTCCT
CCGGGATACATATGTGCCCTCAGCAGCAGCTCCCAGGTGAAGTTACCAGACCCCTGGGCTTCTCCCCAGCTTTTTCTGAGTTGAGTCAGA
CATGTAGAGTTTGGGTCACACAGGCAAGAGGAATTTTCCCTCGGCCTTACTGACAAGGACACCAACCTAGGGTGCAAACAGATGGACTAT
GGTTCAAGGACACTGGAATTGAGGAGCTGATCAAGGCTCTCTTCAGCCTTGCTCTGTCCCTGCCTCTTATCAGAGCACAGGTAGACACAC
GGGCATAGCCAGCCCACTCCTACTGTCACAGGCGCCCCACCATTCAACCTTCCGGGAGGTCAGGGACCTTCTATATGAGGCGAGTGGGTC
TCAGTCTGCTTGAATGGTGATGAGATTCTGCTGGATCTCAGCACGCTGCAGGTGTCTTTTGAGAGCATTCAGTAGGACATGGTGATCCCT
ATTTCAGCCTCTAAGATGACTGGTATTCTATCTGAAATGCAGAGATTAAGCCAAATACCTGATGTATTGTGAAAGCCACTGATTTTAAGA
ATGGAGAGAAAGGGATTTTTTACTGCATCCCTCTGTATGAATATGAAATCAGAGACCAGGGCATGATGTTGCTAGGATTAGAGCCTCTCA
GTCTGGCCTCTTCACCCAAGTGCAAGAACTCAGTCTCTTACTGTTCAAAGAATCTTAACAGTTGAATTATGGAGGGAAATTCCCTTTTGC
CCCAAGCATTTCTATATTTAAAGCAATATCCCAGGAGAATATGTTAGACTTAGGATGATACCTTCAGCCACTTGAAGAAGAAATAGAAGG
CGCTCATTCCAATATAGTCTTTATTTCCCATTCAGATACAGGTTGAGCATCCCTAATCTGAACAGTTAAAACCCCCAAATGCCCCAAAAT
CCAAACCTTCCTGAACGCTATGACACCATGAGTGGAAAATTCCACACCTAACAAACACATTTGCTTTCTTATGGTTCAATGTACACAAAC
TGTTTTATATAGAAAATGATTTCAAATATCATAAAATTACCTTCAGGCTATGTGTATAAAGTATATATGAGCCATAAATGAATTTTGTGT
TTAGACTTTGTGTCCATCCCCAAGATCTCTCATTTTATATATATATATATATATATATATATATATATATATATATATATATACACACAC
ACACACATACACAAATATTCCAGGATACAAAAAAAAACATTTAAAAATCCGAGACCCAGAACACTTCTGGTCCCAAGCATTTCAGATAAG
GGATATCAATCTGTACTACCAATAAGGATTTCGTAATTCCCCTAACTGCAAATGTCCTCTTCATTTGTTCTTTATGAGAAAACCCGGGTA
GTGCCAGCACCTGGATACAGTATTTACACCCTGCAGACCCTAAAGATTTCAGATTCAGTTAGCAAACCTTGATGAAGCACCTGCTGGACA
CTGAGGGACCCAAAGCTCAATCAGCCATAATCCCTGCTTTCAGAGTTTATATTGTACCTGCCTAATCCACCCGGCGTGACTCATTTCAAC
ACTAAGTACTAGGGGTGTTGTCAGGAGACAAATCTGAAGTCAGGAGAGGAAAATGCAAAGGAGCCCTGCCGTGTGATGGATGTGCATTCT
CACTTGGGTCTTGAAGTTCTCATTCCTACATCTCAAGCTAGCCAGGCAGTCTCCTCTCTATCAGAAGAAAGCACTGGTAATTGGCTAGAC
TGGCTATGTTGAAGGTAACATGAACTCTAAGATCTTGACCCAGGGCGACTTGGTTTTGCTTAAGGTGGCATCACCAATGTTCCAAATCCT
TTAGGGAGATGAGGGTATCCCCACAGAAAAAGAGGAATAATAGACCAATGGATTTTCTCCTTTCACCAGTATGTTTGGAACCCTCTGATC
CAATGTCTTTTGATACTGATCTCTTGTCCAAATGAGAATGTCGCTTTAGCTGAAATTCAAATGGCTGTGACAATTTACCGAAATGATGAA
GTAACCACCATTCCCACCTTTCACTGCCTAGGCTCCAAGTCTGAATACATTTTTGAAATAGGAACTCCCTTTTGCAAAAAAGAAACCTGG
GTGTCAGGGAGGTGAAGTGACTTGCCCTAGGAGCAGACAGCATGCCAAGAATGGAATTAGGCTCAGGATCCAGCCTGGGCTCACCCTGTG
TGGCTCATTCCCACCCAGGAAACTGAAGATAAAAGATTTGGGAAAACACACCAAGAAAAAGGGGCAGTTTTCTTTGCCCAAGCATTTGGT
GCTAGTTAGAGGCTGTTCACTCTCTCCTGCTCCTCTTCGGAGTAGAAATAAAGGCTGTGACACAAGGAAGCCAGTGGGGTGGGAGGGAGG
CACCATAATCCCTCCCTAAAACCCACAGAAGACTAACCTGATACTCTTTTGACCCAACTGCATCAACACTAAACAGCTGCAGACCCCCTG
AATCTTTCACACATGCCAAGTGAACATTCTTGATGATTTCTCTTTGTGACCGCAACCACCTGCAAACCAGAACGACTCTAGAATTTCCTT
CCCCGCCCCCCTTTTTGTTTAGTTTCTAATCTCTTGTTTATGAGGTGTGGGGTTTATAAGGGACTGAATCAAATGAATGTAACAAAAAAG
AAAAAAAAAACAAAAAAAAATGCCTTTTCTCAGGGCCAGTGAGTTGCAAATAATTTTTAAAGAAAAGCCTATAATTACATCATCTCAATA

>49742_49742_4_LRP1-ETV6_LRP1_chr12_57539273_ENST00000554174_ETV6_chr12_12037379_ENST00000396373_length(amino acids)=404AA_BP=289
MLLASAHTMLTPPLLLLLPLLSALVAAAIDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGT
ELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFI
CGCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMP
GLKGFVDEHTINISLSLHHCRLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for LRP1-ETV6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneLRP1chr12:57539273chr12:12037379ENST00000243077+6894445_4544280.33333333333334545.0MAFB


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LRP1-ETV6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LRP1-ETV6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource