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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LRP1-MCRS1 (FusionGDB2 ID:49750)

Fusion Gene Summary for LRP1-MCRS1

check button Fusion gene summary
Fusion gene informationFusion gene name: LRP1-MCRS1
Fusion gene ID: 49750
HgeneTgene
Gene symbol

LRP1

MCRS1

Gene ID

10438

10445

Gene nameC1D nuclear receptor corepressormicrospherule protein 1
SynonymsLRP1|Rrp47|SUN-CoR|SUNCOR|hC1DICP22BP|INO80Q|MCRS2|MSP58|P78
Cytomap

2p14

12q13.12

Type of geneprotein-codingprotein-coding
Descriptionnuclear nucleic acid-binding protein C1DC1D DNA-binding proteinC1D nuclear receptor co-repressornuclear DNA-binding proteinsmall unique nuclear receptor co-repressorsmall unique nuclear receptor corepressormicrospherule protein 158 kDa microspherule proteinINO80 complex subunit JINO80 complex subunit Qcell cycle-regulated factor (78 kDa)cell cycle-regulated factor p78
Modification date2020031320200320
UniProtAcc

Q07954

Q96EZ8

Ensembl transtripts involved in fusion geneENST00000243077, ENST00000338962, 
ENST00000553277, ENST00000553446, 
ENST00000554174, 		ENST00000357123, 
ENST00000547182, ENST00000343810, 
ENST00000546244, ENST00000550165, 
Fusion gene scores* DoF score23 X 27 X 12=74524 X 5 X 3=60
# samples 265
** MAII scorelog2(26/7452*10)=-4.84104414591318
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LRP1 [Title/Abstract] AND MCRS1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLRP1(57604662)-MCRS1(49953604), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMCRS1

GO:0043981

histone H4-K5 acetylation

20018852

TgeneMCRS1

GO:0043982

histone H4-K8 acetylation

20018852

TgeneMCRS1

GO:0043984

histone H4-K16 acetylation

20018852

TgeneMCRS1

GO:1904751

positive regulation of protein localization to nucleolus

16571602


check buttonFusion gene breakpoints across LRP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MCRS1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-AB2G-01ALRP1chr12

57604662

-MCRS1chr12

49953604

-


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Fusion Gene ORF analysis for LRP1-MCRS1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000243077ENST00000357123LRP1chr12

57604662

-MCRS1chr12

49953604

-
5CDS-5UTRENST00000243077ENST00000547182LRP1chr12

57604662

-MCRS1chr12

49953604

-
In-frameENST00000243077ENST00000343810LRP1chr12

57604662

-MCRS1chr12

49953604

-
In-frameENST00000243077ENST00000546244LRP1chr12

57604662

-MCRS1chr12

49953604

-
In-frameENST00000243077ENST00000550165LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000338962ENST00000343810LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000338962ENST00000546244LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000338962ENST00000550165LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000553277ENST00000343810LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000553277ENST00000546244LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000553277ENST00000550165LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000553446ENST00000343810LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000553446ENST00000546244LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000553446ENST00000550165LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000554174ENST00000343810LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000554174ENST00000546244LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-3CDSENST00000554174ENST00000550165LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-5UTRENST00000338962ENST00000357123LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-5UTRENST00000338962ENST00000547182LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-5UTRENST00000553277ENST00000357123LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-5UTRENST00000553277ENST00000547182LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-5UTRENST00000553446ENST00000357123LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-5UTRENST00000553446ENST00000547182LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-5UTRENST00000554174ENST00000357123LRP1chr12

57604662

-MCRS1chr12

49953604

-
intron-5UTRENST00000554174ENST00000547182LRP1chr12

57604662

-MCRS1chr12

49953604

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000243077LRP1chr1257604662-ENST00000546244MCRS1chr1249953604-1419913382442138604472
ENST00000243077LRP1chr1257604662-ENST00000343810MCRS1chr1249953604-1418413382442138604472
ENST00000243077LRP1chr1257604662-ENST00000550165MCRS1chr1249953604-1414113382442138604472

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000243077ENST00000546244LRP1chr1257604662-MCRS1chr1249953604-0.0054772150.9945228
ENST00000243077ENST00000343810LRP1chr1257604662-MCRS1chr1249953604-0.0055013580.99449867
ENST00000243077ENST00000550165LRP1chr1257604662-MCRS1chr1249953604-0.0056344550.9943656

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Fusion Genomic Features for LRP1-MCRS1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for LRP1-MCRS1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:57604662/chr12:49953604)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LRP1

Q07954

MCRS1

Q96EZ8

FUNCTION: Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells (PubMed:11907044, PubMed:12713657). Required for early embryonic development (By similarity). Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. Acts as an LRPAP1 alpha-2-macroglobulin receptor (PubMed:26142438, PubMed:1702392). Acts as TAU/MAPT receptor and controls the endocytosis of TAU/MAPT as well as its subsequent spread (PubMed:32296178). May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission (PubMed:12888553). {ECO:0000250|UniProtKB:Q91ZX7, ECO:0000269|PubMed:11907044, ECO:0000269|PubMed:12713657, ECO:0000269|PubMed:12888553, ECO:0000269|PubMed:1702392, ECO:0000269|PubMed:26142438, ECO:0000269|PubMed:32296178}.; FUNCTION: (Microbial infection) Functions as a receptor for Pseudomonas aeruginosa exotoxin A. {ECO:0000269|PubMed:1618748}.FUNCTION: Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA (PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U) (PubMed:16571602). {ECO:0000269|PubMed:11948183, ECO:0000269|PubMed:15044100, ECO:0000269|PubMed:16571602, ECO:0000269|PubMed:20018852}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891013_105343054545.0DomainLDL-receptor class A 7
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891060_109943054545.0DomainLDL-receptor class A 8
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891102_114243054545.0DomainLDL-receptor class A 9
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389111_14943054545.0DomainEGF-like 1
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891143_118243054545.0DomainLDL-receptor class A 10
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891183_122243054545.0DomainEGF-like 5
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891223_126243054545.0DomainEGF-like 6
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389150_18943054545.0DomainEGF-like 2%3B calcium-binding
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891536_157943054545.0DomainEGF-like 7
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891846_188743054545.0DomainEGF-like 8
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892155_219543054545.0DomainEGF-like 9
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892478_251843054545.0DomainEGF-like 10
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892522_256343054545.0DomainLDL-receptor class A 11
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892564_260243054545.0DomainLDL-receptor class A 12
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-838925_6643054545.0DomainLDL-receptor class A 1
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892603_264143054545.0DomainLDL-receptor class A 13
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892642_269043054545.0DomainLDL-receptor class A 14
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892694_273243054545.0DomainLDL-receptor class A 15
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892732_277143054545.0DomainLDL-receptor class A 16
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892772_281443054545.0DomainLDL-receptor class A 17
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892816_285543054545.0DomainLDL-receptor class A 18
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892856_289943054545.0DomainLDL-receptor class A 19
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892902_294043054545.0DomainLDL-receptor class A 20
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892941_298143054545.0DomainEGF-like 11
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892982_302243054545.0DomainEGF-like 12%3B calcium-binding
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893290_333143054545.0DomainEGF-like 13
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893332_337143054545.0DomainLDL-receptor class A 21
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893372_341043054545.0DomainLDL-receptor class A 22
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893411_345043054545.0DomainLDL-receptor class A 23
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893451_349143054545.0DomainLDL-receptor class A 24
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893492_353343054545.0DomainLDL-receptor class A 25
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893534_357243054545.0DomainLDL-receptor class A 26
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893573_361143054545.0DomainLDL-receptor class A 27
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893611_364943054545.0DomainLDL-receptor class A 28
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893652_369243054545.0DomainLDL-receptor class A 29
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893693_373343054545.0DomainLDL-receptor class A 30
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893739_377843054545.0DomainLDL-receptor class A 31
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893781_382343054545.0DomainEGF-like 14
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893824_386143054545.0DomainEGF-like 15
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894147_418343054545.0DomainEGF-like 16
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894196_423243054545.0DomainEGF-like 17
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894232_426843054545.0DomainEGF-like 18
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894268_430443054545.0DomainEGF-like 19
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389474_52043054545.0DomainEGF-like 3
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-838970_11043054545.0DomainLDL-receptor class A 2
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389803_84343054545.0DomainEGF-like 4
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389852_89243054545.0DomainLDL-receptor class A 3
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389893_93343054545.0DomainLDL-receptor class A 4
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389934_97343054545.0DomainLDL-receptor class A 5
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389974_101343054545.0DomainLDL-receptor class A 6
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893940_394343054545.0MotifRecognition site for proteolytical processing
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891309_135543054545.0RepeatNote=LDL-receptor class B 8
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891356_139843054545.0RepeatNote=LDL-receptor class B 9
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891399_144543054545.0RepeatNote=LDL-receptor class B 10
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891446_149043054545.0RepeatNote=LDL-receptor class B 11
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891491_153143054545.0RepeatNote=LDL-receptor class B 12
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891627_166943054545.0RepeatNote=LDL-receptor class B 13
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891670_171343054545.0RepeatNote=LDL-receptor class B 14
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891714_175343054545.0RepeatNote=LDL-receptor class B 15
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891754_179843054545.0RepeatNote=LDL-receptor class B 16
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891934_197643054545.0RepeatNote=LDL-receptor class B 17
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83891977_201943054545.0RepeatNote=LDL-receptor class B 18
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892020_206343054545.0RepeatNote=LDL-receptor class B 19
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892064_210743054545.0RepeatNote=LDL-receptor class B 20
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892253_229443054545.0RepeatNote=LDL-receptor class B 21
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892295_234343054545.0RepeatNote=LDL-receptor class B 22
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892344_238843054545.0RepeatNote=LDL-receptor class B 23
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892389_243143054545.0RepeatNote=LDL-receptor class B 24
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83892432_247343054545.0RepeatNote=LDL-receptor class B 25
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389292_33443054545.0RepeatNote=LDL-receptor class B 1
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893069_311343054545.0RepeatNote=LDL-receptor class B 26
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893114_315643054545.0RepeatNote=LDL-receptor class B 27
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893157_320043054545.0RepeatNote=LDL-receptor class B 28
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893201_324343054545.0RepeatNote=LDL-receptor class B 29
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893244_328443054545.0RepeatNote=LDL-receptor class B 30
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389335_37843054545.0RepeatNote=LDL-receptor class B 2
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389379_42243054545.0RepeatNote=LDL-receptor class B 3
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893912_395443054545.0RepeatNote=LDL-receptor class B 31
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83893970_401243054545.0RepeatNote=LDL-receptor class B 32
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894013_405643054545.0RepeatNote=LDL-receptor class B 33
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894057_410143054545.0RepeatNote=LDL-receptor class B 34
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389571_61343054545.0RepeatNote=LDL-receptor class B 4
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389614_65943054545.0RepeatNote=LDL-receptor class B 5
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389660_71043054545.0RepeatNote=LDL-receptor class B 6
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-8389711_75443054545.0RepeatNote=LDL-receptor class B 7
TgeneMCRS1chr12:57604662chr12:49953604ENST00000343810915301_335303463.0Coiled coilOntology_term=ECO:0000255
TgeneMCRS1chr12:57604662chr12:49953604ENST000005501651016301_335303463.0Coiled coilOntology_term=ECO:0000255
TgeneMCRS1chr12:57604662chr12:49953604ENST00000343810915363_419303463.0DomainFHA
TgeneMCRS1chr12:57604662chr12:49953604ENST00000357123814363_419316476.0DomainFHA
TgeneMCRS1chr12:57604662chr12:49953604ENST000005501651016363_419303463.0DomainFHA

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894304_434043054545.0DomainEGF-like 20
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894340_437543054545.0DomainEGF-like 21
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894373_440943054545.0DomainEGF-like 22
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894502_450743054545.0MotifNote=NPXY motif
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-838920_441943054545.0Topological domainExtracellular
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894420_444443054545.0TransmembraneHelical
TgeneMCRS1chr12:57604662chr12:49953604ENST00000357123814301_335316476.0Coiled coilOntology_term=ECO:0000255
TgeneMCRS1chr12:57604662chr12:49953604ENST0000034381091511_102303463.0Compositional biasNote=Ser-rich
TgeneMCRS1chr12:57604662chr12:49953604ENST0000035712381411_102316476.0Compositional biasNote=Ser-rich
TgeneMCRS1chr12:57604662chr12:49953604ENST00000550165101611_102303463.0Compositional biasNote=Ser-rich
TgeneMCRS1chr12:57604662chr12:49953604ENST00000343810915113_123303463.0MotifNuclear localization signal
TgeneMCRS1chr12:57604662chr12:49953604ENST00000357123814113_123316476.0MotifNuclear localization signal
TgeneMCRS1chr12:57604662chr12:49953604ENST000005501651016113_123303463.0MotifNuclear localization signal


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Fusion Gene Sequence for LRP1-MCRS1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>49750_49750_1_LRP1-MCRS1_LRP1_chr12_57604662_ENST00000243077_MCRS1_chr12_49953604_ENST00000343810_length(transcript)=14184nt_BP=13382nt
CAGCGGTGCGAGCTCCAGGCCCATGCACTGAGGAGGCGGAAACAAGGGGAGCCCCCAGAGCTCCATCAAGCCCCCTCCAAAGGCTCCCCT
ACCCGGTCCACGCCCCCCACCCCCCCTCCCCGCCTCCTCCCAATTGTGCATTTTTGCAGCCGGAGGCGGCTCCGAGATGGGGCTGTGAGC
TTCGCCCGGGGAGGGGGAAAGAGCAGCGAGGAGTGAAGCGGGGGGGTGGGGTGAAGGGTTTGGATTTCGGGGCAGGGGGCGCACCCCCGT
CAGCAGGCCCTCCCCAAGGGGCTCGGAACTCTACCTCTTCACCCACGCCCCTGGTGCGCTTTGCCGAAGGAAAGAATAAGAACAGAGAAG
GAGGAGGGGGAAAGGAGGAAAAGGGGGACCCCCCAACTGGGGGGGGTGAAGGAGAGAAGTAGCAGGACCAGAGGGGAAGGGGCTGCTGCT
TGCATCAGCCCACACCATGCTGACCCCGCCGTTGCTCCTGCTGCTGCCCCTGCTCTCAGCTCTGGTCGCGGCGGCTATCGACGCCCCTAA
GACTTGCAGCCCCAAGCAGTTTGCCTGCAGAGATCAAATAACCTGTATCTCAAAGGGCTGGCGGTGCGACGGTGAGAGGGACTGCCCAGA
CGGATCTGACGAGGCCCCTGAGATTTGTCCACAGAGTAAGGCCCAGCGATGCCAGCCAAACGAGCATAACTGCCTGGGTACTGAGCTGTG
TGTTCCCATGTCCCGCCTCTGCAATGGGGTCCAGGACTGCATGGACGGCTCAGATGAGGGGCCCCACTGCCGAGAGCTCCAAGGCAACTG
CTCTCGCCTGGGCTGCCAGCACCATTGTGTCCCCACACTCGATGGGCCCACCTGCTACTGCAACAGCAGCTTTCAGCTTCAGGCAGATGG
CAAGACCTGCAAAGATTTTGATGAGTGCTCAGTGTACGGCACCTGCAGCCAGCTATGCACCAACACAGACGGCTCCTTCATATGTGGCTG
TGTTGAAGGATACCTCCTGCAGCCGGATAACCGCTCCTGCAAGGCCAAGAACGAGCCAGTAGACCGGCCCCCTGTGCTGTTGATAGCCAA
CTCCCAGAACATCTTGGCCACGTACCTGAGTGGGGCCCAGGTGTCTACCATCACACCTACGAGCACGCGGCAGACCACAGCCATGGACTT
CAGCTATGCCAACGAGACCGTATGCTGGGTGCATGTTGGGGACAGTGCTGCTCAGACGCAGCTCAAGTGTGCCCGCATGCCTGGCCTAAA
GGGCTTCGTGGATGAGCACACCATCAACATCTCCCTCAGTCTGCACCACGTGGAACAGATGGCCATCGACTGGCTGACAGGCAACTTCTA
CTTTGTGGATGACATCGATGATAGGATCTTTGTCTGCAACAGAAATGGGGACACATGTGTCACATTGCTAGACCTGGAACTCTACAACCC
CAAGGGCATTGCCCTGGACCCTGCCATGGGGAAGGTGTTTTTCACTGACTATGGGCAGATCCCAAAGGTGGAACGCTGTGACATGGATGG
GCAGAACCGCACCAAGCTCGTCGACAGCAAGATTGTGTTTCCTCATGGCATCACGCTGGACCTGGTCAGCCGCCTTGTCTACTGGGCAGA
TGCCTATCTGGACTATATTGAAGTGGTGGACTATGAGGGCAAGGGCCGCCAGACCATCATCCAGGGCATCCTGATTGAGCACCTGTACGG
CCTGACTGTGTTTGAGAATTATCTCTATGCCACCAACTCGGACAATGCCAATGCCCAGCAGAAGACGAGTGTGATCCGTGTGAACCGCTT
TAACAGCACCGAGTACCAGGTTGTCACCCGGGTGGACAAGGGTGGTGCCCTCCACATCTACCACCAGAGGCGTCAGCCCCGAGTGAGGAG
CCATGCCTGTGAAAACGACCAGTATGGGAAGCCGGGTGGCTGCTCTGACATCTGCCTGCTGGCCAACAGCCACAAGGCGCGGACCTGCCG
CTGCCGTTCCGGCTTCAGCCTGGGCAGTGACGGGAAGTCATGCAAGAAGCCGGAGCATGAGCTGTTCCTCGTGTATGGCAAGGGCCGGCC
AGGCATCATCCGGGGCATGGATATGGGGGCCAAGGTCCCGGATGAGCACATGATCCCCATTGAAAACCTCATGAACCCCCGAGCCCTGGA
CTTCCACGCTGAGACCGGCTTCATCTACTTTGCCGACACCACCAGCTACCTCATTGGCCGCCAGAAGATTGATGGCACTGAGCGGGAGAC
CATCCTGAAGGACGGCATCCACAATGTGGAGGGTGTGGCCGTGGACTGGATGGGAGACAATCTGTACTGGACGGACGATGGGCCCAAAAA
GACAATCAGCGTGGCCAGGCTGGAGAAAGCTGCTCAGACCCGCAAGACTTTAATCGAGGGCAAAATGACACACCCCAGGGCTATTGTGGT
GGATCCACTCAATGGGTGGATGTACTGGACAGACTGGGAGGAGGACCCCAAGGACAGTCGGCGTGGGCGGCTGGAGAGGGCGTGGATGGA
TGGCTCACACCGAGACATCTTTGTCACCTCCAAGACAGTGCTTTGGCCCAATGGGCTAAGCCTGGACATCCCGGCTGGGCGCCTCTACTG
GGTGGATGCCTTCTACGACCGCATCGAGACGATACTGCTCAATGGCACAGACCGGAAGATTGTGTATGAAGGTCCTGAGCTGAACCACGC
CTTTGGCCTGTGTCACCATGGCAACTACCTCTTCTGGACTGAGTATCGGAGTGGCAGTGTCTACCGCTTGGAACGGGGTGTAGGAGGCGC
ACCCCCCACTGTGACCCTTCTGCGCAGTGAGCGGCCCCCCATCTTTGAGATCCGAATGTATGATGCCCAGCAGCAGCAAGTTGGCACCAA
CAAATGCCGGGTGAACAATGGCGGCTGCAGCAGCCTGTGCTTGGCCACCCCTGGGAGCCGCCAGTGCGCCTGTGCTGAGGACCAGGTGTT
GGACGCAGACGGCGTCACTTGCTTGGCGAACCCATCCTACGTGCCTCCACCCCAGTGCCAGCCAGGCGAGTTTGCCTGTGCCAACAGCCG
CTGCATCCAGGAGCGCTGGAAGTGTGACGGAGACAACGATTGCCTGGACAACAGTGATGAGGCCCCAGCCCTCTGCCATCAGCACACCTG
CCCCTCGGACCGATTCAAGTGCGAGAACAACCGGTGCATCCCCAACCGCTGGCTCTGCGACGGGGACAATGACTGTGGGAACAGTGAAGA
TGAGTCCAATGCCACTTGTTCAGCCCGCACCTGCCCCCCCAACCAGTTCTCCTGTGCCAGTGGCCGCTGCATCCCCATCTCCTGGACGTG
TGATCTGGATGACGACTGTGGGGACCGCTCTGATGAGTCTGCTTCGTGTGCCTATCCCACCTGCTTCCCCCTGACTCAGTTTACCTGCAA
CAATGGCAGATGTATCAACATCAACTGGAGATGCGACAATGACAATGACTGTGGGGACAACAGTGACGAAGCCGGCTGCAGCCACTCCTG
TTCTAGCACCCAGTTCAAGTGCAACAGCGGGCGTTGCATCCCCGAGCACTGGACCTGCGATGGGGACAATGACTGCGGAGACTACAGTGA
TGAGACACACGCCAACTGCACCAACCAGGCCACGAGGCCCCCTGGTGGCTGCCACACTGATGAGTTCCAGTGCCGGCTGGATGGACTATG
CATCCCCCTGCGGTGGCGCTGCGATGGGGACACTGACTGCATGGACTCCAGCGATGAGAAGAGCTGTGAGGGAGTGACCCACGTCTGCGA
TCCCAGTGTCAAGTTTGGCTGCAAGGACTCAGCTCGGTGCATCAGCAAAGCGTGGGTGTGTGATGGCGACAATGACTGTGAGGATAACTC
GGACGAGGAGAACTGCGAGTCCCTGGCCTGCAGGCCACCCTCGCACCCTTGTGCCAACAACACCTCAGTCTGCCTGCCCCCTGACAAGCT
GTGTGATGGCAACGACGACTGTGGCGACGGCTCAGATGAGGGCGAGCTCTGCGACCAGTGCTCTCTGAATAACGGTGGCTGCAGCCACAA
CTGCTCAGTGGCACCTGGCGAAGGCATTGTGTGTTCCTGCCCTCTGGGCATGGAGCTGGGGCCCGACAACCACACCTGCCAGATCCAGAG
CTACTGTGCCAAGCATCTCAAATGCAGCCAAAAGTGCGACCAGAACAAGTTCAGCGTGAAGTGCTCCTGCTACGAGGGCTGGGTCCTGGA
ACCTGACGGCGAGAGCTGCCGCAGCCTGGACCCCTTCAAGCCGTTCATCATTTTCTCCAACCGCCATGAAATCCGGCGCATCGATCTTCA
CAAAGGAGACTACAGCGTCCTGGTGCCCGGCCTGCGCAACACCATCGCCCTGGACTTCCACCTCAGCCAGAGCGCCCTCTACTGGACCGA
CGTGGTGGAGGACAAGATCTACCGCGGGAAGCTGCTGGACAACGGAGCCCTGACTAGTTTCGAGGTGGTGATTCAGTATGGCCTGGCCAC
ACCCGAGGGCCTGGCTGTAGACTGGATTGCAGGCAACATCTACTGGGTGGAGAGTAACCTGGATCAGATCGAGGTGGCCAAGCTGGATGG
GACCCTCCGGACCACCCTGCTGGCCGGTGACATTGAGCACCCAAGGGCAATCGCACTGGATCCCCGGGATGGGATCCTGTTTTGGACAGA
CTGGGATGCCAGCCTGCCCCGCATTGAGGCAGCCTCCATGAGTGGGGCTGGGCGCCGCACCGTGCACCGGGAGACCGGCTCTGGGGGCTG
GCCCAACGGGCTCACCGTGGACTACCTGGAGAAGCGCATCCTTTGGATTGACGCCAGGTCAGATGCCATTTACTCAGCCCGTTACGACGG
CTCTGGCCACATGGAGGTGCTTCGGGGACACGAGTTCCTGTCGCACCCGTTTGCAGTGACGCTGTACGGGGGGGAGGTCTACTGGACTGA
CTGGCGAACAAACACACTGGCTAAGGCCAACAAGTGGACCGGCCACAATGTCACCGTGGTACAGAGGACCAACACCCAGCCCTTTGACCT
GCAGGTGTACCACCCCTCCCGCCAGCCCATGGCTCCCAATCCCTGTGAGGCCAATGGGGGCCAGGGCCCCTGCTCCCACCTGTGTCTCAT
CAACTACAACCGGACCGTGTCCTGCGCCTGCCCCCACCTCATGAAGCTCCACAAGGACAACACCACCTGCTATGAGTTTAAGAAGTTCCT
GCTGTACGCACGTCAGATGGAGATCCGAGGTGTGGACCTGGATGCTCCCTACTACAACTACATCATCTCCTTCACGGTGCCCGACATCGA
CAACGTCACAGTGCTAGACTACGATGCCCGCGAGCAGCGTGTGTACTGGTCTGACGTGCGGACACAGGCCATCAAGCGGGCCTTCATCAA
CGGCACAGGCGTGGAGACAGTCGTCTCTGCAGACTTGCCAAATGCCCACGGGCTGGCTGTGGACTGGGTCTCCCGAAACCTGTTCTGGAC
AAGCTATGACACCAATAAGAAGCAGATCAATGTGGCCCGGCTGGATGGCTCCTTCAAGAACGCAGTGGTGCAGGGCCTGGAGCAGCCCCA
TGGCCTTGTCGTCCACCCTCTGCGTGGGAAGCTCTACTGGACCGATGGTGACAACATCAGCATGGCCAACATGGATGGCAGCAATCGCAC
CCTGCTCTTCAGTGGCCAGAAGGGCCCCGTGGGCCTGGCTATTGACTTCCCTGAAAGCAAACTCTACTGGATCAGCTCCGGGAACCATAC
CATCAACCGCTGCAACCTGGATGGGAGTGGGCTGGAGGTCATCGATGCCATGCGGAGCCAGCTGGGCAAGGCCACCGCCCTGGCCATCAT
GGGGGACAAGCTGTGGTGGGCTGATCAGGTGTCGGAAAAGATGGGCACATGCAGCAAGGCTGACGGCTCGGGCTCCGTGGTCCTTCGGAA
CAGCACCACCCTGGTGATGCACATGAAGGTCTATGACGAGAGCATCCAGCTGGACCATAAGGGCACCAACCCCTGCAGTGTCAACAACGG
TGACTGCTCCCAGCTCTGCCTGCCCACGTCAGAGACGACCCGCTCCTGCATGTGCACAGCCGGCTATAGCCTCCGGAGTGGCCAGCAGGC
CTGCGAGGGCGTAGGTTCCTTTCTCCTGTACTCTGTGCATGAGGGAATCAGGGGAATTCCCCTGGATCCCAATGACAAGTCAGATGCCCT
GGTCCCAGTGTCCGGGACCTCGCTGGCTGTCGGCATCGACTTCCACGCTGAAAATGACACCATCTACTGGGTGGACATGGGCCTGAGCAC
GATCAGCCGGGCCAAGCGGGACCAGACGTGGCGTGAAGACGTGGTGACCAATGGCATTGGCCGTGTGGAGGGCATTGCAGTGGACTGGAT
CGCAGGCAACATCTACTGGACAGACCAGGGCTTTGATGTCATCGAGGTCGCCCGGCTCAATGGCTCCTTCCGCTACGTGGTGATCTCCCA
GGGTCTAGACAAGCCCCGGGCCATCACCGTCCACCCGGAGAAAGGGTACTTGTTCTGGACTGAGTGGGGTCAGTATCCGCGTATTGAGCG
GTCTCGGCTAGATGGCACGGAGCGTGTGGTGCTGGTCAACGTCAGCATCAGCTGGCCCAACGGCATCTCAGTGGACTACCAGGATGGGAA
GCTGTACTGGTGCGATGCACGGACAGACAAGATTGAACGGATCGACCTGGAGACAGGTGAGAACCGCGAGGTGGTTCTGTCCAGCAACAA
CATGGACATGTTTTCAGTGTCTGTGTTTGAGGATTTCATCTACTGGAGTGACAGGACTCATGCCAACGGCTCTATCAAGCGCGGGAGCAA
AGACAATGCCACAGACTCCGTGCCCCTGCGAACCGGCATCGGCGTCCAGCTTAAAGACATCAAAGTCTTCAACCGGGACCGGCAGAAAGG
CACCAACGTGTGCGCGGTGGCCAATGGCGGGTGCCAGCAGCTGTGCCTGTACCGGGGCCGTGGGCAGCGGGCCTGCGCCTGTGCCCACGG
GATGCTGGCTGAAGACGGAGCATCGTGCCGCGAGTATGCCGGCTACCTGCTCTACTCAGAGCGCACCATTCTCAAGAGTATCCACCTGTC
GGATGAGCGCAACCTCAATGCGCCCGTGCAGCCCTTCGAGGACCCTGAGCACATGAAGAACGTCATCGCCCTGGCCTTTGACTACCGGGC
AGGCACCTCTCCGGGCACCCCCAATCGCATCTTCTTCAGCGACATCCACTTTGGGAACATCCAACAGATCAACGACGATGGCTCCAGGAG
GATCACCATTGTGGAAAACGTGGGCTCCGTGGAAGGCCTGGCCTATCACCGTGGCTGGGACACTCTCTATTGGACAAGCTACACGACATC
CACCATCACGCGCCACACAGTGGACCAGACCCGCCCAGGGGCCTTCGAGCGTGAGACCGTCATCACTATGTCTGGAGATGACCACCCACG
GGCCTTCGTTTTGGACGAGTGCCAGAACCTCATGTTCTGGACCAACTGGAATGAGCAGCATCCCAGCATCATGCGGGCGGCGCTCTCGGG
AGCCAATGTCCTGACCCTTATCGAGAAGGACATCCGTACCCCCAATGGCCTGGCCATCGACCACCGTGCCGAGAAGCTCTACTTCTCTGA
CGCCACCCTGGACAAGATCGAGCGGTGCGAGTATGACGGCTCCCACCGCTATGTGATCCTAAAGTCAGAGCCTGTCCACCCCTTCGGGCT
GGCCGTGTATGGGGAGCACATTTTCTGGACTGACTGGGTGCGGCGGGCAGTGCAGCGGGCCAACAAGCACGTGGGCAGCAACATGAAGCT
GCTGCGCGTGGACATCCCCCAGCAGCCCATGGGCATCATCGCCGTGGCCAACGACACCAACAGCTGTGAACTCTCTCCATGCCGAATCAA
CAACGGTGGCTGCCAGGACCTGTGTCTGCTCACTCACCAGGGCCATGTCAACTGCTCATGCCGAGGGGGCCGAATCCTCCAGGATGACCT
CACCTGCCGAGCGGTGAATTCCTCTTGCCGAGCACAAGATGAGTTTGAGTGTGCCAATGGCGAGTGCATCAACTTCAGCCTGACCTGCGA
CGGCGTCCCCCACTGCAAGGACAAGTCCGATGAGAAGCCATCCTACTGCAACTCCCGCCGCTGCAAGAAGACTTTCCGGCAGTGCAGCAA
TGGGCGCTGTGTGTCCAACATGCTGTGGTGCAACGGGGCCGACGACTGTGGGGATGGCTCTGACGAGATCCCTTGCAACAAGACAGCCTG
TGGTGTGGGCGAGTTCCGCTGCCGGGACGGGACCTGCATCGGGAACTCCAGCCGCTGCAACCAGTTTGTGGATTGTGAGGACGCCTCAGA
TGAGATGAACTGCAGTGCCACCGACTGCAGCAGCTACTTCCGCCTGGGCGTGAAGGGCGTGCTCTTCCAGCCCTGCGAGCGGACCTCACT
CTGCTACGCACCCAGCTGGGTGTGTGATGGCGCCAATGACTGTGGGGACTACAGTGATGAGCGCGACTGCCCAGGTGTGAAACGCCCCAG
ATGCCCTCTGAATTACTTCGCCTGCCCTAGTGGGCGCTGCATCCCCATGAGCTGGACGTGTGACAAAGAGGATGACTGTGAACATGGCGA
GGACGAGACCCACTGCAACAAGTTCTGCTCAGAGGCCCAGTTTGAGTGCCAGAACCATCGCTGCATCTCCAAGCAGTGGCTGTGTGACGG
CAGCGATGACTGTGGGGATGGCTCAGACGAGGCTGCTCACTGTGAAGGCAAGACGTGCGGCCCCTCCTCCTTCTCCTGCCCTGGCACCCA
CGTGTGCGTCCCCGAGCGCTGGCTCTGTGACGGTGACAAAGACTGTGCTGATGGTGCAGACGAGAGCATCGCAGCTGGTTGCTTGTACAA
CAGCACTTGTGACGACCGTGAGTTCATGTGCCAGAACCGCCAGTGCATCCCCAAGCACTTCGTGTGTGACCACGACCGTGACTGTGCAGA
TGGCTCTGATGAGTCCCCCGAGTGTGAGTACCCGACCTGCGGCCCCAGTGAGTTCCGCTGTGCCAATGGGCGCTGTCTGAGCTCCCGCCA
GTGGGAGTGTGATGGCGAGAATGACTGCCACGACCAGAGTGACGAGGCTCCCAAGAACCCACACTGCACCAGCCAAGAGCACAAGTGCAA
TGCCTCGTCACAGTTCCTGTGCAGCAGTGGGCGCTGTGTGGCTGAGGCACTGCTCTGCAACGGCCAGGATGACTGTGGCGACAGCTCGGA
CGAGCGTGGCTGCCACATCAATGAGTGTCTCAGCCGCAAGCTCAGTGGCTGCAGCCAGGACTGTGAGGACCTCAAGATCGGCTTCAAGTG
CCGCTGTCGCCCTGGCTTCCGGCTGAAGGACGACGGCCGGACGTGTGCTGATGTGGACGAGTGCAGCACCACCTTCCCCTGCAGCCAGCG
CTGCATCAACACTCATGGCAGCTATAAGTGTCTGTGTGTGGAGGGCTATGCACCCCGCGGCGGCGACCCCCACAGCTGCAAGGCTGTGAC
TGACGAGGAACCGTTTCTGATCTTCGCCAACCGGTACTACCTGCGCAAGCTCAACCTGGACGGGTCCAACTACACGTTACTTAAGCAGGG
CCTGAACAACGCCGTTGCCTTGGATTTTGACTACCGAGAGCAGATGATCTACTGGACAGATGTGACCACCCAGGGCAGCATGATCCGAAG
GATGCACCTTAACGGGAGCAATGTGCAGGTCCTACACCGTACAGGCCTCAGCAACCCCGATGGGCTGGCTGTGGACTGGGTGGGTGGCAA
CCTGTACTGGTGCGACAAAGGCCGGGACACCATCGAGGTGTCCAAGCTCAATGGGGCCTATCGGACGGTGCTGGTCAGCTCTGGCCTCCG
TGAGCCCAGGGCTCTGGTGGTGGATGTGCAGAATGGGTACCTGTACTGGACAGACTGGGGTGACCATTCACTGATCGGCCGCATCGGCAT
GGATGGGTCCAGCCGCAGCGTCATCGTGGACACCAAGATCACATGGCCCAATGGCCTGACGCTGGACTATGTCACTGAGCGCATCTACTG
GGCCGACGCCCGCGAGGACTACATTGAATTTGCCAGCCTGGATGGCTCCAATCGCCACGTTGTGCTGAGCCAGGACATCCCGCACATCTT
TGCACTGACCCTGTTTGAGGACTACGTCTACTGGACCGACTGGGAAACAAAGTCCATTAACCGAGCCCACAAGACCACGGGCACCAACAA
AACGCTCCTCATCAGCACGCTGCACCGGCCCATGGACCTGCATGTCTTCCATGCCCTGCGCCAGCCAGACGTGCCCAATCACCCCTGCAA
GGTCAACAATGGTGGCTGCAGCAACCTGTGCCTGCTGTCCCCCGGGGGAGGGCACAAATGTGCCTGCCCCACCAACTTCTACCTGGGCAG
CGATGGGCGCACCTGTGTGTCCAACTGCACGGCTAGCCAGTTTGTATGCAAGAACGACAAGTGCATCCCCTTCTGGTGGAAGTGTGACAC
CGAGGACGACTGCGGGGACCACTCAGACGAGCCCCCGGACTGCCCTGAGTTCAAGTGCCGGCCCGGACAGTTCCAGTGCTCCACAGGTAT
CTGCACAAACCCTGCCTTCATCTGCGATGGCGACAATGACTGCCAGGACAACAGTGACGAGGCCAACTGTGACATCCACGTCTGCTTGCC
CAGTCAGTTCAAATGCACCAACACCAACCGCTGTATTCCCGGCATCTTCCGCTGCAATGGGCAGGACAACTGCGGAGATGGGGAGGATGA
GAGGGACTGCCCCGAGGTGACCTGCGCCCCCAACCAGTTCCAGTGCTCCATTACCAAACGGTGCATCCCCCGGGTCTGGGTCTGCGACCG
GGACAATGACTGTGTGGATGGCAGTGATGAGCCCGCCAACTGCACCCAGATGACCTGTGGTGTGGACGAGTTCCGCTGCAAGGATTCGGG
CCGCTGCATCCCAGCGCGTTGGAAGTGTGACGGAGAGGATGACTGTGGGGATGGCTCGGATGAGCCCAAGGAAGAGTGTGATGAACGCAC
CTGTGAGCCATACCAGTTCCGCTGCAAGAACAACCGCTGCGTGCCCGGCCGCTGGCAGTGCGACTACGACAACGATTGCGGTGACAACTC
CGATGAAGAGAGCTGCACCCCTCGGCCCTGCTCCGAGAGTGAGTTCTCCTGTGCCAACGGCCGCTGCATCGCGGGGCGCTGGAAATGCGA
TGGAGACCACGACTGCGCGGACGGCTCGGACGAGAAAGACTGCACCCCCCGCTGTGACATGGACCAGTTCCAGTGCAAGAGCGGCCACTG
CATCCCCCTGCGCTGGCGCTGTGACGCAGACGCCGACTGCATGGACGGCAGCGACGAGGAGGCCTGCGGCACTGGCGTGCGGACCTGCCC
CCTGGACGAGTTCCAGTGCAACAACACCTTGTGCAAGCCGCTGGCCTGGAAGTGCGATGGCGAGGATGACTGTGGGGACAACTCAGATGA
GAACCCCGAGGAGTGTGCCCGGTTCGTGTGCCCTCCCAACCGGCCCTTCCGTTGCAAGAATGACCGCGTCTGTCTGTGGATCGGGCGCCA
ATGCGATGGCACGGACAACTGTGGGGATGGGACTGATGAAGAGGACTGTGAGCCCCCCACAGCCCACACCACCCACTGCAAAGACAAGAA
GGAGTTTCTGTGCCGGAACCAGCGCTGCCTCTCCTCCTCCCTGCGCTGCAACATGTTCGATGACTGCGGGGACGGCTCTGACGAGGAGGA
CTGCAGCATCGACCCCAAGCTGACCAGCTGCGCCACCAATGCCAGCATCTGTGGGGACGAGGCACGCTGCGTGCGCACCGAGAAAGCGGC
CTACTGTGCCTGCCGCTCGGGCTTCCACACCGTGCCCGGCCAGCCCGGATGCCAAGACATCAACGAGTGCCTGCGCTTCGGCACCTGCTC
CCAGCTCTGCAACAACACCAAGGGCGGCCACCTCTGCAGCTGCGCTCGGAACTTCATGAAGACGCACAACACCTGCAAGGCCGAAGGCTC
TGAGTACCAGGTCCTGTACATCGCTGATGACAATGAGATCCGCAGCCTGTTCCCCGGCCACCCCCATTCGGCTTACGAGCAGGCATTCCA
GGGTGACGAGAGTGTCCGCATTGATGCTATGGATGTCCATGTCAAGGCTGGCCGTGTCTATTGGACCAACTGGCACACGGGCACCATCTC
CTACCGCAGCCTGCCACCTGCTGCGCCTCCTACCACTTCCAACCGCCACCGGCGACAGATTGACCGGGGTGTCACCCACCTCAACATTTC
AGGGCTGAAGATGCCCAGAGGCATCGCCATCGACTGGGTGGCCGGAAACGTGTACTGGACCGACTCGGGCCGAGATGTGATTGAGGTGGC
GCAGATGAAGGGCGAGAACCGCAAGACGCTCATCTCGGGCATGATTGACGAGCCCCACGCCATTGTGGTGGACCCACTGAGGGGGACCAT
GTACTGGTCAGACTGGGGCAACCACCCCAAGATTGAGACGGCAGCGATGGATGGGACGCTTCGGGAGACACTGGTGCAGGACAACATTCA
GTGGCCCACAGGCCTGGCCGTGGATTATCACAATGAGCGGCTGTACTGGGCAGACGCCAAGCTTTCAGTCATCGGCAGCATCCGGCTCAA
TGGCACGGACCCCATTGTGGCTGCTGACAGCAAACGAGGCCTAAGTCACCCCTTCAGCATCGACGTCTTTGAGGATTACATCTATGGTGT
CACCTACATCAATAATCGTGTCTTCAAGATCCATAAGTTTGGCCACAGCCCCTTGGTCAACCTGACAGGGGGCCTGAGCCACGCCTCTGA
CGTGGTCCTTTACCATCAGCACAAGCAGCCCGAAGTGACCAACCCATGTGACCGCAAGAAATGCGAGTGGCTCTGCCTGCTGAGCCCCAG
TGGGCCTGTCTGCACCTGTCCCAATGGGAAGCGGCTGGACAACGGCACATGCGTGCCTGTGCCCTCTCCAACGCCCCCCCCAGATGCTCC
CCGGCCTGGAACCTGTAACCTGCAGTGCTTCAACGGTGGCAGCTGTTTCCTCAATGCACGGAGGCAGCCCAAGTGCCGCTGCCAACCCCG
CTACACGGGTGACAAGTGTGAACTGGACCAGTGCTGGGAGCACTGTCGCAATGGGGGCACCTGTGCTGCCTCCCCCTCTGGCATGCCCAC
GTGCCGGTGCCCCACGGGCTTCACGGGCCCCAAATGCACCCAGCAGGTGTGTGCGGGCTACTGTGCCAACAACAGCACCTGCACTGTCAA
CCAGGGCAACCAGCCCCAGTGCCGATGCCTACCCGGCTTCCTGGGCGACCGCTGCCAGTACCAGCTGATGGTGGCTGACCGGCGCCAGAA
GCGAGAGATTCGGCAGCTGGAACAGGAACTGCATAAGTGGCAGGTGCTAGTGGACAGCATCACAGGCATGAGCTCTCCGGACTTCGACAA
CCAGACACTGGCAGTGCTGCGGGGCCGCATGGTGCGGTACCTGATGCGCTCGCGTGAGATCACCCTGGGCAGAGCAACCAAGGATAACCA
GATTGATGTGGACCTGTCTCTGGAGGGTCCGGCCTGGAAGATATCCCGGAAACAAGGTGTCATCAAGCTGAAGAACAACGGTGATTTCTT
CATTGCCAATGAGGGTCGACGGCCCATCTACATCGATGGACGGCCGGTGCTCTGTGGCTCCAAATGGCGCCTCAGCAACAACTCTGTGGT
GGAGATCGCCAGCCTGCGATTCGTCTTCCTTATCAACCAGGACCTCATTGCCCTCATCAGGGCTGAGGCTGCCAAGATCACACCACAGTG
AGGAGTGGTGGCAGGACTCGTGGGCCCTCTCCGGCCTGTTTCCCCTGCCACTCCAGCCCCCTTGAGCTGGGAACTCAGGCTCCTGGAAAA
ACCTGGGCAGTGGGAGGCTCAGCTGCGGGCCATTGATTTGAGCCTTTGAGGGAGGATAGGGCTGGCCTTTGTGAAGCCAGCAGAGGCTGA
GAACCTCAGGCTTCCCTAGATCCAGAGCCCCTCCCCATCTTCCTCTCTCTAAAAACAACCCTACCCCCCATTGCCACCTTCACTCCTGTG

>49750_49750_1_LRP1-MCRS1_LRP1_chr12_57604662_ENST00000243077_MCRS1_chr12_49953604_ENST00000343810_length(amino acids)=4472AA_BP=4314
MLLASAHTMLTPPLLLLLPLLSALVAAAIDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGT
ELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFI
CGCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMP
GLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCD
MDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDNANAQQKTSVIRV
NRFNSTEYQVVTRVDKGGALHIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKPEHELFLVYGK
GRPGIIRGMDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDG
PKKTISVARLEKAAQTRKTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGR
LYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGSVYRLERGVGGAPPTVTLLRSERPPIFEIRMYDAQQQQV
GTNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQCQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQ
HTCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQF
TCNNGRCININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLD
GLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNTSVCLPP
DKLCDGNDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGW
VLEPDGESCRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYG
LATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTVHRETGS
GGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTVVQRTNTQP
FDLQVYHPSRQPMAPNPCEANGGQGPCSHLCLINYNRTVSCACPHLMKLHKDNTTCYEFKKFLLYARQMEIRGVDLDAPYYNYIISFTVP
DIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSADLPNAHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQGLE
QPHGLVVHPLRGKLYWTDGDNISMANMDGSNRTLLFSGQKGPVGLAIDFPESKLYWISSGNHTINRCNLDGSGLEVIDAMRSQLGKATAL
AIMGDKLWWADQVSEKMGTCSKADGSGSVVLRNSTTLVMHMKVYDESIQLDHKGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSG
QQACEGVGSFLLYSVHEGIRGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWREDVVTNGIGRVEGIAV
DWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQYPRIERSRLDGTERVVLVNVSISWPNGISVDYQ
DGKLYWCDARTDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGSIKRGSKDNATDSVPLRTGIGVQLKDIKVFNRDR
QKGTNVCAVANGGCQQLCLYRGRGQRACACAHGMLAEDGASCREYAGYLLYSERTILKSIHLSDERNLNAPVQPFEDPEHMKNVIALAFD
YRAGTSPGTPNRIFFSDIHFGNIQQINDDGSRRITIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDD
HPRAFVLDECQNLMFWTNWNEQHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHP
FGLAVYGEHIFWTDWVRRAVQRANKHVGSNMKLLRVDIPQQPMGIIAVANDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQ
DDLTCRAVNSSCRAQDEFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADDCGDGSDEIPCNK
TACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVK
RPRCPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCP
GTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRCLS
SRQWECDGENDCHDQSDEAPKNPHCTSQEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSGCSQDCEDLKIG
FKCRCRPGFRLKDDGRTCADVDECSTTFPCSQRCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLL
KQGLNNAVALDFDYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSS
GLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSRSVIVDTKITWPNGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIP
HIFALTLFEDYVYWTDWETKSINRAHKTTGTNKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGGGHKCACPTNFY
LGSDGRTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHV
CLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCK
DSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRW
KCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDN
SDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSD
EEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINECLRFGTCSQLCNNTKGGHLCSCARNFMKTHNTCKA
EGSEYQVLYIADDNEIRSLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHL
NISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQD
NIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGHSPLVNLTGGLSH
ASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPSGPVCTCPNGKRLDNGTCVPVPSPTPPPDAPRPGTCNLQCFNGGSCFLNARRQPKCRC
QPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQYQLMVADR
RQKREIRQLEQELHKWQVLVDSITGMSSPDFDNQTLAVLRGRMVRYLMRSREITLGRATKDNQIDVDLSLEGPAWKISRKQGVIKLKNNG

--------------------------------------------------------------
>49750_49750_2_LRP1-MCRS1_LRP1_chr12_57604662_ENST00000243077_MCRS1_chr12_49953604_ENST00000546244_length(transcript)=14199nt_BP=13382nt
CAGCGGTGCGAGCTCCAGGCCCATGCACTGAGGAGGCGGAAACAAGGGGAGCCCCCAGAGCTCCATCAAGCCCCCTCCAAAGGCTCCCCT
ACCCGGTCCACGCCCCCCACCCCCCCTCCCCGCCTCCTCCCAATTGTGCATTTTTGCAGCCGGAGGCGGCTCCGAGATGGGGCTGTGAGC
TTCGCCCGGGGAGGGGGAAAGAGCAGCGAGGAGTGAAGCGGGGGGGTGGGGTGAAGGGTTTGGATTTCGGGGCAGGGGGCGCACCCCCGT
CAGCAGGCCCTCCCCAAGGGGCTCGGAACTCTACCTCTTCACCCACGCCCCTGGTGCGCTTTGCCGAAGGAAAGAATAAGAACAGAGAAG
GAGGAGGGGGAAAGGAGGAAAAGGGGGACCCCCCAACTGGGGGGGGTGAAGGAGAGAAGTAGCAGGACCAGAGGGGAAGGGGCTGCTGCT
TGCATCAGCCCACACCATGCTGACCCCGCCGTTGCTCCTGCTGCTGCCCCTGCTCTCAGCTCTGGTCGCGGCGGCTATCGACGCCCCTAA
GACTTGCAGCCCCAAGCAGTTTGCCTGCAGAGATCAAATAACCTGTATCTCAAAGGGCTGGCGGTGCGACGGTGAGAGGGACTGCCCAGA
CGGATCTGACGAGGCCCCTGAGATTTGTCCACAGAGTAAGGCCCAGCGATGCCAGCCAAACGAGCATAACTGCCTGGGTACTGAGCTGTG
TGTTCCCATGTCCCGCCTCTGCAATGGGGTCCAGGACTGCATGGACGGCTCAGATGAGGGGCCCCACTGCCGAGAGCTCCAAGGCAACTG
CTCTCGCCTGGGCTGCCAGCACCATTGTGTCCCCACACTCGATGGGCCCACCTGCTACTGCAACAGCAGCTTTCAGCTTCAGGCAGATGG
CAAGACCTGCAAAGATTTTGATGAGTGCTCAGTGTACGGCACCTGCAGCCAGCTATGCACCAACACAGACGGCTCCTTCATATGTGGCTG
TGTTGAAGGATACCTCCTGCAGCCGGATAACCGCTCCTGCAAGGCCAAGAACGAGCCAGTAGACCGGCCCCCTGTGCTGTTGATAGCCAA
CTCCCAGAACATCTTGGCCACGTACCTGAGTGGGGCCCAGGTGTCTACCATCACACCTACGAGCACGCGGCAGACCACAGCCATGGACTT
CAGCTATGCCAACGAGACCGTATGCTGGGTGCATGTTGGGGACAGTGCTGCTCAGACGCAGCTCAAGTGTGCCCGCATGCCTGGCCTAAA
GGGCTTCGTGGATGAGCACACCATCAACATCTCCCTCAGTCTGCACCACGTGGAACAGATGGCCATCGACTGGCTGACAGGCAACTTCTA
CTTTGTGGATGACATCGATGATAGGATCTTTGTCTGCAACAGAAATGGGGACACATGTGTCACATTGCTAGACCTGGAACTCTACAACCC
CAAGGGCATTGCCCTGGACCCTGCCATGGGGAAGGTGTTTTTCACTGACTATGGGCAGATCCCAAAGGTGGAACGCTGTGACATGGATGG
GCAGAACCGCACCAAGCTCGTCGACAGCAAGATTGTGTTTCCTCATGGCATCACGCTGGACCTGGTCAGCCGCCTTGTCTACTGGGCAGA
TGCCTATCTGGACTATATTGAAGTGGTGGACTATGAGGGCAAGGGCCGCCAGACCATCATCCAGGGCATCCTGATTGAGCACCTGTACGG
CCTGACTGTGTTTGAGAATTATCTCTATGCCACCAACTCGGACAATGCCAATGCCCAGCAGAAGACGAGTGTGATCCGTGTGAACCGCTT
TAACAGCACCGAGTACCAGGTTGTCACCCGGGTGGACAAGGGTGGTGCCCTCCACATCTACCACCAGAGGCGTCAGCCCCGAGTGAGGAG
CCATGCCTGTGAAAACGACCAGTATGGGAAGCCGGGTGGCTGCTCTGACATCTGCCTGCTGGCCAACAGCCACAAGGCGCGGACCTGCCG
CTGCCGTTCCGGCTTCAGCCTGGGCAGTGACGGGAAGTCATGCAAGAAGCCGGAGCATGAGCTGTTCCTCGTGTATGGCAAGGGCCGGCC
AGGCATCATCCGGGGCATGGATATGGGGGCCAAGGTCCCGGATGAGCACATGATCCCCATTGAAAACCTCATGAACCCCCGAGCCCTGGA
CTTCCACGCTGAGACCGGCTTCATCTACTTTGCCGACACCACCAGCTACCTCATTGGCCGCCAGAAGATTGATGGCACTGAGCGGGAGAC
CATCCTGAAGGACGGCATCCACAATGTGGAGGGTGTGGCCGTGGACTGGATGGGAGACAATCTGTACTGGACGGACGATGGGCCCAAAAA
GACAATCAGCGTGGCCAGGCTGGAGAAAGCTGCTCAGACCCGCAAGACTTTAATCGAGGGCAAAATGACACACCCCAGGGCTATTGTGGT
GGATCCACTCAATGGGTGGATGTACTGGACAGACTGGGAGGAGGACCCCAAGGACAGTCGGCGTGGGCGGCTGGAGAGGGCGTGGATGGA
TGGCTCACACCGAGACATCTTTGTCACCTCCAAGACAGTGCTTTGGCCCAATGGGCTAAGCCTGGACATCCCGGCTGGGCGCCTCTACTG
GGTGGATGCCTTCTACGACCGCATCGAGACGATACTGCTCAATGGCACAGACCGGAAGATTGTGTATGAAGGTCCTGAGCTGAACCACGC
CTTTGGCCTGTGTCACCATGGCAACTACCTCTTCTGGACTGAGTATCGGAGTGGCAGTGTCTACCGCTTGGAACGGGGTGTAGGAGGCGC
ACCCCCCACTGTGACCCTTCTGCGCAGTGAGCGGCCCCCCATCTTTGAGATCCGAATGTATGATGCCCAGCAGCAGCAAGTTGGCACCAA
CAAATGCCGGGTGAACAATGGCGGCTGCAGCAGCCTGTGCTTGGCCACCCCTGGGAGCCGCCAGTGCGCCTGTGCTGAGGACCAGGTGTT
GGACGCAGACGGCGTCACTTGCTTGGCGAACCCATCCTACGTGCCTCCACCCCAGTGCCAGCCAGGCGAGTTTGCCTGTGCCAACAGCCG
CTGCATCCAGGAGCGCTGGAAGTGTGACGGAGACAACGATTGCCTGGACAACAGTGATGAGGCCCCAGCCCTCTGCCATCAGCACACCTG
CCCCTCGGACCGATTCAAGTGCGAGAACAACCGGTGCATCCCCAACCGCTGGCTCTGCGACGGGGACAATGACTGTGGGAACAGTGAAGA
TGAGTCCAATGCCACTTGTTCAGCCCGCACCTGCCCCCCCAACCAGTTCTCCTGTGCCAGTGGCCGCTGCATCCCCATCTCCTGGACGTG
TGATCTGGATGACGACTGTGGGGACCGCTCTGATGAGTCTGCTTCGTGTGCCTATCCCACCTGCTTCCCCCTGACTCAGTTTACCTGCAA
CAATGGCAGATGTATCAACATCAACTGGAGATGCGACAATGACAATGACTGTGGGGACAACAGTGACGAAGCCGGCTGCAGCCACTCCTG
TTCTAGCACCCAGTTCAAGTGCAACAGCGGGCGTTGCATCCCCGAGCACTGGACCTGCGATGGGGACAATGACTGCGGAGACTACAGTGA
TGAGACACACGCCAACTGCACCAACCAGGCCACGAGGCCCCCTGGTGGCTGCCACACTGATGAGTTCCAGTGCCGGCTGGATGGACTATG
CATCCCCCTGCGGTGGCGCTGCGATGGGGACACTGACTGCATGGACTCCAGCGATGAGAAGAGCTGTGAGGGAGTGACCCACGTCTGCGA
TCCCAGTGTCAAGTTTGGCTGCAAGGACTCAGCTCGGTGCATCAGCAAAGCGTGGGTGTGTGATGGCGACAATGACTGTGAGGATAACTC
GGACGAGGAGAACTGCGAGTCCCTGGCCTGCAGGCCACCCTCGCACCCTTGTGCCAACAACACCTCAGTCTGCCTGCCCCCTGACAAGCT
GTGTGATGGCAACGACGACTGTGGCGACGGCTCAGATGAGGGCGAGCTCTGCGACCAGTGCTCTCTGAATAACGGTGGCTGCAGCCACAA
CTGCTCAGTGGCACCTGGCGAAGGCATTGTGTGTTCCTGCCCTCTGGGCATGGAGCTGGGGCCCGACAACCACACCTGCCAGATCCAGAG
CTACTGTGCCAAGCATCTCAAATGCAGCCAAAAGTGCGACCAGAACAAGTTCAGCGTGAAGTGCTCCTGCTACGAGGGCTGGGTCCTGGA
ACCTGACGGCGAGAGCTGCCGCAGCCTGGACCCCTTCAAGCCGTTCATCATTTTCTCCAACCGCCATGAAATCCGGCGCATCGATCTTCA
CAAAGGAGACTACAGCGTCCTGGTGCCCGGCCTGCGCAACACCATCGCCCTGGACTTCCACCTCAGCCAGAGCGCCCTCTACTGGACCGA
CGTGGTGGAGGACAAGATCTACCGCGGGAAGCTGCTGGACAACGGAGCCCTGACTAGTTTCGAGGTGGTGATTCAGTATGGCCTGGCCAC
ACCCGAGGGCCTGGCTGTAGACTGGATTGCAGGCAACATCTACTGGGTGGAGAGTAACCTGGATCAGATCGAGGTGGCCAAGCTGGATGG
GACCCTCCGGACCACCCTGCTGGCCGGTGACATTGAGCACCCAAGGGCAATCGCACTGGATCCCCGGGATGGGATCCTGTTTTGGACAGA
CTGGGATGCCAGCCTGCCCCGCATTGAGGCAGCCTCCATGAGTGGGGCTGGGCGCCGCACCGTGCACCGGGAGACCGGCTCTGGGGGCTG
GCCCAACGGGCTCACCGTGGACTACCTGGAGAAGCGCATCCTTTGGATTGACGCCAGGTCAGATGCCATTTACTCAGCCCGTTACGACGG
CTCTGGCCACATGGAGGTGCTTCGGGGACACGAGTTCCTGTCGCACCCGTTTGCAGTGACGCTGTACGGGGGGGAGGTCTACTGGACTGA
CTGGCGAACAAACACACTGGCTAAGGCCAACAAGTGGACCGGCCACAATGTCACCGTGGTACAGAGGACCAACACCCAGCCCTTTGACCT
GCAGGTGTACCACCCCTCCCGCCAGCCCATGGCTCCCAATCCCTGTGAGGCCAATGGGGGCCAGGGCCCCTGCTCCCACCTGTGTCTCAT
CAACTACAACCGGACCGTGTCCTGCGCCTGCCCCCACCTCATGAAGCTCCACAAGGACAACACCACCTGCTATGAGTTTAAGAAGTTCCT
GCTGTACGCACGTCAGATGGAGATCCGAGGTGTGGACCTGGATGCTCCCTACTACAACTACATCATCTCCTTCACGGTGCCCGACATCGA
CAACGTCACAGTGCTAGACTACGATGCCCGCGAGCAGCGTGTGTACTGGTCTGACGTGCGGACACAGGCCATCAAGCGGGCCTTCATCAA
CGGCACAGGCGTGGAGACAGTCGTCTCTGCAGACTTGCCAAATGCCCACGGGCTGGCTGTGGACTGGGTCTCCCGAAACCTGTTCTGGAC
AAGCTATGACACCAATAAGAAGCAGATCAATGTGGCCCGGCTGGATGGCTCCTTCAAGAACGCAGTGGTGCAGGGCCTGGAGCAGCCCCA
TGGCCTTGTCGTCCACCCTCTGCGTGGGAAGCTCTACTGGACCGATGGTGACAACATCAGCATGGCCAACATGGATGGCAGCAATCGCAC
CCTGCTCTTCAGTGGCCAGAAGGGCCCCGTGGGCCTGGCTATTGACTTCCCTGAAAGCAAACTCTACTGGATCAGCTCCGGGAACCATAC
CATCAACCGCTGCAACCTGGATGGGAGTGGGCTGGAGGTCATCGATGCCATGCGGAGCCAGCTGGGCAAGGCCACCGCCCTGGCCATCAT
GGGGGACAAGCTGTGGTGGGCTGATCAGGTGTCGGAAAAGATGGGCACATGCAGCAAGGCTGACGGCTCGGGCTCCGTGGTCCTTCGGAA
CAGCACCACCCTGGTGATGCACATGAAGGTCTATGACGAGAGCATCCAGCTGGACCATAAGGGCACCAACCCCTGCAGTGTCAACAACGG
TGACTGCTCCCAGCTCTGCCTGCCCACGTCAGAGACGACCCGCTCCTGCATGTGCACAGCCGGCTATAGCCTCCGGAGTGGCCAGCAGGC
CTGCGAGGGCGTAGGTTCCTTTCTCCTGTACTCTGTGCATGAGGGAATCAGGGGAATTCCCCTGGATCCCAATGACAAGTCAGATGCCCT
GGTCCCAGTGTCCGGGACCTCGCTGGCTGTCGGCATCGACTTCCACGCTGAAAATGACACCATCTACTGGGTGGACATGGGCCTGAGCAC
GATCAGCCGGGCCAAGCGGGACCAGACGTGGCGTGAAGACGTGGTGACCAATGGCATTGGCCGTGTGGAGGGCATTGCAGTGGACTGGAT
CGCAGGCAACATCTACTGGACAGACCAGGGCTTTGATGTCATCGAGGTCGCCCGGCTCAATGGCTCCTTCCGCTACGTGGTGATCTCCCA
GGGTCTAGACAAGCCCCGGGCCATCACCGTCCACCCGGAGAAAGGGTACTTGTTCTGGACTGAGTGGGGTCAGTATCCGCGTATTGAGCG
GTCTCGGCTAGATGGCACGGAGCGTGTGGTGCTGGTCAACGTCAGCATCAGCTGGCCCAACGGCATCTCAGTGGACTACCAGGATGGGAA
GCTGTACTGGTGCGATGCACGGACAGACAAGATTGAACGGATCGACCTGGAGACAGGTGAGAACCGCGAGGTGGTTCTGTCCAGCAACAA
CATGGACATGTTTTCAGTGTCTGTGTTTGAGGATTTCATCTACTGGAGTGACAGGACTCATGCCAACGGCTCTATCAAGCGCGGGAGCAA
AGACAATGCCACAGACTCCGTGCCCCTGCGAACCGGCATCGGCGTCCAGCTTAAAGACATCAAAGTCTTCAACCGGGACCGGCAGAAAGG
CACCAACGTGTGCGCGGTGGCCAATGGCGGGTGCCAGCAGCTGTGCCTGTACCGGGGCCGTGGGCAGCGGGCCTGCGCCTGTGCCCACGG
GATGCTGGCTGAAGACGGAGCATCGTGCCGCGAGTATGCCGGCTACCTGCTCTACTCAGAGCGCACCATTCTCAAGAGTATCCACCTGTC
GGATGAGCGCAACCTCAATGCGCCCGTGCAGCCCTTCGAGGACCCTGAGCACATGAAGAACGTCATCGCCCTGGCCTTTGACTACCGGGC
AGGCACCTCTCCGGGCACCCCCAATCGCATCTTCTTCAGCGACATCCACTTTGGGAACATCCAACAGATCAACGACGATGGCTCCAGGAG
GATCACCATTGTGGAAAACGTGGGCTCCGTGGAAGGCCTGGCCTATCACCGTGGCTGGGACACTCTCTATTGGACAAGCTACACGACATC
CACCATCACGCGCCACACAGTGGACCAGACCCGCCCAGGGGCCTTCGAGCGTGAGACCGTCATCACTATGTCTGGAGATGACCACCCACG
GGCCTTCGTTTTGGACGAGTGCCAGAACCTCATGTTCTGGACCAACTGGAATGAGCAGCATCCCAGCATCATGCGGGCGGCGCTCTCGGG
AGCCAATGTCCTGACCCTTATCGAGAAGGACATCCGTACCCCCAATGGCCTGGCCATCGACCACCGTGCCGAGAAGCTCTACTTCTCTGA
CGCCACCCTGGACAAGATCGAGCGGTGCGAGTATGACGGCTCCCACCGCTATGTGATCCTAAAGTCAGAGCCTGTCCACCCCTTCGGGCT
GGCCGTGTATGGGGAGCACATTTTCTGGACTGACTGGGTGCGGCGGGCAGTGCAGCGGGCCAACAAGCACGTGGGCAGCAACATGAAGCT
GCTGCGCGTGGACATCCCCCAGCAGCCCATGGGCATCATCGCCGTGGCCAACGACACCAACAGCTGTGAACTCTCTCCATGCCGAATCAA
CAACGGTGGCTGCCAGGACCTGTGTCTGCTCACTCACCAGGGCCATGTCAACTGCTCATGCCGAGGGGGCCGAATCCTCCAGGATGACCT
CACCTGCCGAGCGGTGAATTCCTCTTGCCGAGCACAAGATGAGTTTGAGTGTGCCAATGGCGAGTGCATCAACTTCAGCCTGACCTGCGA
CGGCGTCCCCCACTGCAAGGACAAGTCCGATGAGAAGCCATCCTACTGCAACTCCCGCCGCTGCAAGAAGACTTTCCGGCAGTGCAGCAA
TGGGCGCTGTGTGTCCAACATGCTGTGGTGCAACGGGGCCGACGACTGTGGGGATGGCTCTGACGAGATCCCTTGCAACAAGACAGCCTG
TGGTGTGGGCGAGTTCCGCTGCCGGGACGGGACCTGCATCGGGAACTCCAGCCGCTGCAACCAGTTTGTGGATTGTGAGGACGCCTCAGA
TGAGATGAACTGCAGTGCCACCGACTGCAGCAGCTACTTCCGCCTGGGCGTGAAGGGCGTGCTCTTCCAGCCCTGCGAGCGGACCTCACT
CTGCTACGCACCCAGCTGGGTGTGTGATGGCGCCAATGACTGTGGGGACTACAGTGATGAGCGCGACTGCCCAGGTGTGAAACGCCCCAG
ATGCCCTCTGAATTACTTCGCCTGCCCTAGTGGGCGCTGCATCCCCATGAGCTGGACGTGTGACAAAGAGGATGACTGTGAACATGGCGA
GGACGAGACCCACTGCAACAAGTTCTGCTCAGAGGCCCAGTTTGAGTGCCAGAACCATCGCTGCATCTCCAAGCAGTGGCTGTGTGACGG
CAGCGATGACTGTGGGGATGGCTCAGACGAGGCTGCTCACTGTGAAGGCAAGACGTGCGGCCCCTCCTCCTTCTCCTGCCCTGGCACCCA
CGTGTGCGTCCCCGAGCGCTGGCTCTGTGACGGTGACAAAGACTGTGCTGATGGTGCAGACGAGAGCATCGCAGCTGGTTGCTTGTACAA
CAGCACTTGTGACGACCGTGAGTTCATGTGCCAGAACCGCCAGTGCATCCCCAAGCACTTCGTGTGTGACCACGACCGTGACTGTGCAGA
TGGCTCTGATGAGTCCCCCGAGTGTGAGTACCCGACCTGCGGCCCCAGTGAGTTCCGCTGTGCCAATGGGCGCTGTCTGAGCTCCCGCCA
GTGGGAGTGTGATGGCGAGAATGACTGCCACGACCAGAGTGACGAGGCTCCCAAGAACCCACACTGCACCAGCCAAGAGCACAAGTGCAA
TGCCTCGTCACAGTTCCTGTGCAGCAGTGGGCGCTGTGTGGCTGAGGCACTGCTCTGCAACGGCCAGGATGACTGTGGCGACAGCTCGGA
CGAGCGTGGCTGCCACATCAATGAGTGTCTCAGCCGCAAGCTCAGTGGCTGCAGCCAGGACTGTGAGGACCTCAAGATCGGCTTCAAGTG
CCGCTGTCGCCCTGGCTTCCGGCTGAAGGACGACGGCCGGACGTGTGCTGATGTGGACGAGTGCAGCACCACCTTCCCCTGCAGCCAGCG
CTGCATCAACACTCATGGCAGCTATAAGTGTCTGTGTGTGGAGGGCTATGCACCCCGCGGCGGCGACCCCCACAGCTGCAAGGCTGTGAC
TGACGAGGAACCGTTTCTGATCTTCGCCAACCGGTACTACCTGCGCAAGCTCAACCTGGACGGGTCCAACTACACGTTACTTAAGCAGGG
CCTGAACAACGCCGTTGCCTTGGATTTTGACTACCGAGAGCAGATGATCTACTGGACAGATGTGACCACCCAGGGCAGCATGATCCGAAG
GATGCACCTTAACGGGAGCAATGTGCAGGTCCTACACCGTACAGGCCTCAGCAACCCCGATGGGCTGGCTGTGGACTGGGTGGGTGGCAA
CCTGTACTGGTGCGACAAAGGCCGGGACACCATCGAGGTGTCCAAGCTCAATGGGGCCTATCGGACGGTGCTGGTCAGCTCTGGCCTCCG
TGAGCCCAGGGCTCTGGTGGTGGATGTGCAGAATGGGTACCTGTACTGGACAGACTGGGGTGACCATTCACTGATCGGCCGCATCGGCAT
GGATGGGTCCAGCCGCAGCGTCATCGTGGACACCAAGATCACATGGCCCAATGGCCTGACGCTGGACTATGTCACTGAGCGCATCTACTG
GGCCGACGCCCGCGAGGACTACATTGAATTTGCCAGCCTGGATGGCTCCAATCGCCACGTTGTGCTGAGCCAGGACATCCCGCACATCTT
TGCACTGACCCTGTTTGAGGACTACGTCTACTGGACCGACTGGGAAACAAAGTCCATTAACCGAGCCCACAAGACCACGGGCACCAACAA
AACGCTCCTCATCAGCACGCTGCACCGGCCCATGGACCTGCATGTCTTCCATGCCCTGCGCCAGCCAGACGTGCCCAATCACCCCTGCAA
GGTCAACAATGGTGGCTGCAGCAACCTGTGCCTGCTGTCCCCCGGGGGAGGGCACAAATGTGCCTGCCCCACCAACTTCTACCTGGGCAG
CGATGGGCGCACCTGTGTGTCCAACTGCACGGCTAGCCAGTTTGTATGCAAGAACGACAAGTGCATCCCCTTCTGGTGGAAGTGTGACAC
CGAGGACGACTGCGGGGACCACTCAGACGAGCCCCCGGACTGCCCTGAGTTCAAGTGCCGGCCCGGACAGTTCCAGTGCTCCACAGGTAT
CTGCACAAACCCTGCCTTCATCTGCGATGGCGACAATGACTGCCAGGACAACAGTGACGAGGCCAACTGTGACATCCACGTCTGCTTGCC
CAGTCAGTTCAAATGCACCAACACCAACCGCTGTATTCCCGGCATCTTCCGCTGCAATGGGCAGGACAACTGCGGAGATGGGGAGGATGA
GAGGGACTGCCCCGAGGTGACCTGCGCCCCCAACCAGTTCCAGTGCTCCATTACCAAACGGTGCATCCCCCGGGTCTGGGTCTGCGACCG
GGACAATGACTGTGTGGATGGCAGTGATGAGCCCGCCAACTGCACCCAGATGACCTGTGGTGTGGACGAGTTCCGCTGCAAGGATTCGGG
CCGCTGCATCCCAGCGCGTTGGAAGTGTGACGGAGAGGATGACTGTGGGGATGGCTCGGATGAGCCCAAGGAAGAGTGTGATGAACGCAC
CTGTGAGCCATACCAGTTCCGCTGCAAGAACAACCGCTGCGTGCCCGGCCGCTGGCAGTGCGACTACGACAACGATTGCGGTGACAACTC
CGATGAAGAGAGCTGCACCCCTCGGCCCTGCTCCGAGAGTGAGTTCTCCTGTGCCAACGGCCGCTGCATCGCGGGGCGCTGGAAATGCGA
TGGAGACCACGACTGCGCGGACGGCTCGGACGAGAAAGACTGCACCCCCCGCTGTGACATGGACCAGTTCCAGTGCAAGAGCGGCCACTG
CATCCCCCTGCGCTGGCGCTGTGACGCAGACGCCGACTGCATGGACGGCAGCGACGAGGAGGCCTGCGGCACTGGCGTGCGGACCTGCCC
CCTGGACGAGTTCCAGTGCAACAACACCTTGTGCAAGCCGCTGGCCTGGAAGTGCGATGGCGAGGATGACTGTGGGGACAACTCAGATGA
GAACCCCGAGGAGTGTGCCCGGTTCGTGTGCCCTCCCAACCGGCCCTTCCGTTGCAAGAATGACCGCGTCTGTCTGTGGATCGGGCGCCA
ATGCGATGGCACGGACAACTGTGGGGATGGGACTGATGAAGAGGACTGTGAGCCCCCCACAGCCCACACCACCCACTGCAAAGACAAGAA
GGAGTTTCTGTGCCGGAACCAGCGCTGCCTCTCCTCCTCCCTGCGCTGCAACATGTTCGATGACTGCGGGGACGGCTCTGACGAGGAGGA
CTGCAGCATCGACCCCAAGCTGACCAGCTGCGCCACCAATGCCAGCATCTGTGGGGACGAGGCACGCTGCGTGCGCACCGAGAAAGCGGC
CTACTGTGCCTGCCGCTCGGGCTTCCACACCGTGCCCGGCCAGCCCGGATGCCAAGACATCAACGAGTGCCTGCGCTTCGGCACCTGCTC
CCAGCTCTGCAACAACACCAAGGGCGGCCACCTCTGCAGCTGCGCTCGGAACTTCATGAAGACGCACAACACCTGCAAGGCCGAAGGCTC
TGAGTACCAGGTCCTGTACATCGCTGATGACAATGAGATCCGCAGCCTGTTCCCCGGCCACCCCCATTCGGCTTACGAGCAGGCATTCCA
GGGTGACGAGAGTGTCCGCATTGATGCTATGGATGTCCATGTCAAGGCTGGCCGTGTCTATTGGACCAACTGGCACACGGGCACCATCTC
CTACCGCAGCCTGCCACCTGCTGCGCCTCCTACCACTTCCAACCGCCACCGGCGACAGATTGACCGGGGTGTCACCCACCTCAACATTTC
AGGGCTGAAGATGCCCAGAGGCATCGCCATCGACTGGGTGGCCGGAAACGTGTACTGGACCGACTCGGGCCGAGATGTGATTGAGGTGGC
GCAGATGAAGGGCGAGAACCGCAAGACGCTCATCTCGGGCATGATTGACGAGCCCCACGCCATTGTGGTGGACCCACTGAGGGGGACCAT
GTACTGGTCAGACTGGGGCAACCACCCCAAGATTGAGACGGCAGCGATGGATGGGACGCTTCGGGAGACACTGGTGCAGGACAACATTCA
GTGGCCCACAGGCCTGGCCGTGGATTATCACAATGAGCGGCTGTACTGGGCAGACGCCAAGCTTTCAGTCATCGGCAGCATCCGGCTCAA
TGGCACGGACCCCATTGTGGCTGCTGACAGCAAACGAGGCCTAAGTCACCCCTTCAGCATCGACGTCTTTGAGGATTACATCTATGGTGT
CACCTACATCAATAATCGTGTCTTCAAGATCCATAAGTTTGGCCACAGCCCCTTGGTCAACCTGACAGGGGGCCTGAGCCACGCCTCTGA
CGTGGTCCTTTACCATCAGCACAAGCAGCCCGAAGTGACCAACCCATGTGACCGCAAGAAATGCGAGTGGCTCTGCCTGCTGAGCCCCAG
TGGGCCTGTCTGCACCTGTCCCAATGGGAAGCGGCTGGACAACGGCACATGCGTGCCTGTGCCCTCTCCAACGCCCCCCCCAGATGCTCC
CCGGCCTGGAACCTGTAACCTGCAGTGCTTCAACGGTGGCAGCTGTTTCCTCAATGCACGGAGGCAGCCCAAGTGCCGCTGCCAACCCCG
CTACACGGGTGACAAGTGTGAACTGGACCAGTGCTGGGAGCACTGTCGCAATGGGGGCACCTGTGCTGCCTCCCCCTCTGGCATGCCCAC
GTGCCGGTGCCCCACGGGCTTCACGGGCCCCAAATGCACCCAGCAGGTGTGTGCGGGCTACTGTGCCAACAACAGCACCTGCACTGTCAA
CCAGGGCAACCAGCCCCAGTGCCGATGCCTACCCGGCTTCCTGGGCGACCGCTGCCAGTACCAGCTGATGGTGGCTGACCGGCGCCAGAA
GCGAGAGATTCGGCAGCTGGAACAGGAACTGCATAAGTGGCAGGTGCTAGTGGACAGCATCACAGGCATGAGCTCTCCGGACTTCGACAA
CCAGACACTGGCAGTGCTGCGGGGCCGCATGGTGCGGTACCTGATGCGCTCGCGTGAGATCACCCTGGGCAGAGCAACCAAGGATAACCA
GATTGATGTGGACCTGTCTCTGGAGGGTCCGGCCTGGAAGATATCCCGGAAACAAGGTGTCATCAAGCTGAAGAACAACGGTGATTTCTT
CATTGCCAATGAGGGTCGACGGCCCATCTACATCGATGGACGGCCGGTGCTCTGTGGCTCCAAATGGCGCCTCAGCAACAACTCTGTGGT
GGAGATCGCCAGCCTGCGATTCGTCTTCCTTATCAACCAGGACCTCATTGCCCTCATCAGGGCTGAGGCTGCCAAGATCACACCACAGTG
AGGAGTGGTGGCAGGACTCGTGGGCCCTCTCCGGCCTGTTTCCCCTGCCACTCCAGCCCCCTTGAGCTGGGAACTCAGGCTCCTGGAAAA
ACCTGGGCAGTGGGAGGCTCAGCTGCGGGCCATTGATTTGAGCCTTTGAGGGAGGATAGGGCTGGCCTTTGTGAAGCCAGCAGAGGCTGA
GAACCTCAGGCTTCCCTAGATCCAGAGCCCCTCCCCATCTTCCTCTCTCTAAAAACAACCCTACCCCCCATTGCCACCTTCACTCCTGTG

>49750_49750_2_LRP1-MCRS1_LRP1_chr12_57604662_ENST00000243077_MCRS1_chr12_49953604_ENST00000546244_length(amino acids)=4472AA_BP=4314
MLLASAHTMLTPPLLLLLPLLSALVAAAIDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGT
ELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFI
CGCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMP
GLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCD
MDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDNANAQQKTSVIRV
NRFNSTEYQVVTRVDKGGALHIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKPEHELFLVYGK
GRPGIIRGMDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDG
PKKTISVARLEKAAQTRKTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGR
LYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGSVYRLERGVGGAPPTVTLLRSERPPIFEIRMYDAQQQQV
GTNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQCQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQ
HTCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQF
TCNNGRCININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLD
GLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNTSVCLPP
DKLCDGNDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGW
VLEPDGESCRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYG
LATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTVHRETGS
GGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTVVQRTNTQP
FDLQVYHPSRQPMAPNPCEANGGQGPCSHLCLINYNRTVSCACPHLMKLHKDNTTCYEFKKFLLYARQMEIRGVDLDAPYYNYIISFTVP
DIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSADLPNAHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQGLE
QPHGLVVHPLRGKLYWTDGDNISMANMDGSNRTLLFSGQKGPVGLAIDFPESKLYWISSGNHTINRCNLDGSGLEVIDAMRSQLGKATAL
AIMGDKLWWADQVSEKMGTCSKADGSGSVVLRNSTTLVMHMKVYDESIQLDHKGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSG
QQACEGVGSFLLYSVHEGIRGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWREDVVTNGIGRVEGIAV
DWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQYPRIERSRLDGTERVVLVNVSISWPNGISVDYQ
DGKLYWCDARTDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGSIKRGSKDNATDSVPLRTGIGVQLKDIKVFNRDR
QKGTNVCAVANGGCQQLCLYRGRGQRACACAHGMLAEDGASCREYAGYLLYSERTILKSIHLSDERNLNAPVQPFEDPEHMKNVIALAFD
YRAGTSPGTPNRIFFSDIHFGNIQQINDDGSRRITIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDD
HPRAFVLDECQNLMFWTNWNEQHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHP
FGLAVYGEHIFWTDWVRRAVQRANKHVGSNMKLLRVDIPQQPMGIIAVANDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQ
DDLTCRAVNSSCRAQDEFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADDCGDGSDEIPCNK
TACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVK
RPRCPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCP
GTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRCLS
SRQWECDGENDCHDQSDEAPKNPHCTSQEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSGCSQDCEDLKIG
FKCRCRPGFRLKDDGRTCADVDECSTTFPCSQRCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLL
KQGLNNAVALDFDYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSS
GLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSRSVIVDTKITWPNGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIP
HIFALTLFEDYVYWTDWETKSINRAHKTTGTNKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGGGHKCACPTNFY
LGSDGRTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHV
CLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCK
DSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRW
KCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDN
SDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSD
EEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINECLRFGTCSQLCNNTKGGHLCSCARNFMKTHNTCKA
EGSEYQVLYIADDNEIRSLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHL
NISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQD
NIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGHSPLVNLTGGLSH
ASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPSGPVCTCPNGKRLDNGTCVPVPSPTPPPDAPRPGTCNLQCFNGGSCFLNARRQPKCRC
QPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQYQLMVADR
RQKREIRQLEQELHKWQVLVDSITGMSSPDFDNQTLAVLRGRMVRYLMRSREITLGRATKDNQIDVDLSLEGPAWKISRKQGVIKLKNNG

--------------------------------------------------------------
>49750_49750_3_LRP1-MCRS1_LRP1_chr12_57604662_ENST00000243077_MCRS1_chr12_49953604_ENST00000550165_length(transcript)=14141nt_BP=13382nt
CAGCGGTGCGAGCTCCAGGCCCATGCACTGAGGAGGCGGAAACAAGGGGAGCCCCCAGAGCTCCATCAAGCCCCCTCCAAAGGCTCCCCT
ACCCGGTCCACGCCCCCCACCCCCCCTCCCCGCCTCCTCCCAATTGTGCATTTTTGCAGCCGGAGGCGGCTCCGAGATGGGGCTGTGAGC
TTCGCCCGGGGAGGGGGAAAGAGCAGCGAGGAGTGAAGCGGGGGGGTGGGGTGAAGGGTTTGGATTTCGGGGCAGGGGGCGCACCCCCGT
CAGCAGGCCCTCCCCAAGGGGCTCGGAACTCTACCTCTTCACCCACGCCCCTGGTGCGCTTTGCCGAAGGAAAGAATAAGAACAGAGAAG
GAGGAGGGGGAAAGGAGGAAAAGGGGGACCCCCCAACTGGGGGGGGTGAAGGAGAGAAGTAGCAGGACCAGAGGGGAAGGGGCTGCTGCT
TGCATCAGCCCACACCATGCTGACCCCGCCGTTGCTCCTGCTGCTGCCCCTGCTCTCAGCTCTGGTCGCGGCGGCTATCGACGCCCCTAA
GACTTGCAGCCCCAAGCAGTTTGCCTGCAGAGATCAAATAACCTGTATCTCAAAGGGCTGGCGGTGCGACGGTGAGAGGGACTGCCCAGA
CGGATCTGACGAGGCCCCTGAGATTTGTCCACAGAGTAAGGCCCAGCGATGCCAGCCAAACGAGCATAACTGCCTGGGTACTGAGCTGTG
TGTTCCCATGTCCCGCCTCTGCAATGGGGTCCAGGACTGCATGGACGGCTCAGATGAGGGGCCCCACTGCCGAGAGCTCCAAGGCAACTG
CTCTCGCCTGGGCTGCCAGCACCATTGTGTCCCCACACTCGATGGGCCCACCTGCTACTGCAACAGCAGCTTTCAGCTTCAGGCAGATGG
CAAGACCTGCAAAGATTTTGATGAGTGCTCAGTGTACGGCACCTGCAGCCAGCTATGCACCAACACAGACGGCTCCTTCATATGTGGCTG
TGTTGAAGGATACCTCCTGCAGCCGGATAACCGCTCCTGCAAGGCCAAGAACGAGCCAGTAGACCGGCCCCCTGTGCTGTTGATAGCCAA
CTCCCAGAACATCTTGGCCACGTACCTGAGTGGGGCCCAGGTGTCTACCATCACACCTACGAGCACGCGGCAGACCACAGCCATGGACTT
CAGCTATGCCAACGAGACCGTATGCTGGGTGCATGTTGGGGACAGTGCTGCTCAGACGCAGCTCAAGTGTGCCCGCATGCCTGGCCTAAA
GGGCTTCGTGGATGAGCACACCATCAACATCTCCCTCAGTCTGCACCACGTGGAACAGATGGCCATCGACTGGCTGACAGGCAACTTCTA
CTTTGTGGATGACATCGATGATAGGATCTTTGTCTGCAACAGAAATGGGGACACATGTGTCACATTGCTAGACCTGGAACTCTACAACCC
CAAGGGCATTGCCCTGGACCCTGCCATGGGGAAGGTGTTTTTCACTGACTATGGGCAGATCCCAAAGGTGGAACGCTGTGACATGGATGG
GCAGAACCGCACCAAGCTCGTCGACAGCAAGATTGTGTTTCCTCATGGCATCACGCTGGACCTGGTCAGCCGCCTTGTCTACTGGGCAGA
TGCCTATCTGGACTATATTGAAGTGGTGGACTATGAGGGCAAGGGCCGCCAGACCATCATCCAGGGCATCCTGATTGAGCACCTGTACGG
CCTGACTGTGTTTGAGAATTATCTCTATGCCACCAACTCGGACAATGCCAATGCCCAGCAGAAGACGAGTGTGATCCGTGTGAACCGCTT
TAACAGCACCGAGTACCAGGTTGTCACCCGGGTGGACAAGGGTGGTGCCCTCCACATCTACCACCAGAGGCGTCAGCCCCGAGTGAGGAG
CCATGCCTGTGAAAACGACCAGTATGGGAAGCCGGGTGGCTGCTCTGACATCTGCCTGCTGGCCAACAGCCACAAGGCGCGGACCTGCCG
CTGCCGTTCCGGCTTCAGCCTGGGCAGTGACGGGAAGTCATGCAAGAAGCCGGAGCATGAGCTGTTCCTCGTGTATGGCAAGGGCCGGCC
AGGCATCATCCGGGGCATGGATATGGGGGCCAAGGTCCCGGATGAGCACATGATCCCCATTGAAAACCTCATGAACCCCCGAGCCCTGGA
CTTCCACGCTGAGACCGGCTTCATCTACTTTGCCGACACCACCAGCTACCTCATTGGCCGCCAGAAGATTGATGGCACTGAGCGGGAGAC
CATCCTGAAGGACGGCATCCACAATGTGGAGGGTGTGGCCGTGGACTGGATGGGAGACAATCTGTACTGGACGGACGATGGGCCCAAAAA
GACAATCAGCGTGGCCAGGCTGGAGAAAGCTGCTCAGACCCGCAAGACTTTAATCGAGGGCAAAATGACACACCCCAGGGCTATTGTGGT
GGATCCACTCAATGGGTGGATGTACTGGACAGACTGGGAGGAGGACCCCAAGGACAGTCGGCGTGGGCGGCTGGAGAGGGCGTGGATGGA
TGGCTCACACCGAGACATCTTTGTCACCTCCAAGACAGTGCTTTGGCCCAATGGGCTAAGCCTGGACATCCCGGCTGGGCGCCTCTACTG
GGTGGATGCCTTCTACGACCGCATCGAGACGATACTGCTCAATGGCACAGACCGGAAGATTGTGTATGAAGGTCCTGAGCTGAACCACGC
CTTTGGCCTGTGTCACCATGGCAACTACCTCTTCTGGACTGAGTATCGGAGTGGCAGTGTCTACCGCTTGGAACGGGGTGTAGGAGGCGC
ACCCCCCACTGTGACCCTTCTGCGCAGTGAGCGGCCCCCCATCTTTGAGATCCGAATGTATGATGCCCAGCAGCAGCAAGTTGGCACCAA
CAAATGCCGGGTGAACAATGGCGGCTGCAGCAGCCTGTGCTTGGCCACCCCTGGGAGCCGCCAGTGCGCCTGTGCTGAGGACCAGGTGTT
GGACGCAGACGGCGTCACTTGCTTGGCGAACCCATCCTACGTGCCTCCACCCCAGTGCCAGCCAGGCGAGTTTGCCTGTGCCAACAGCCG
CTGCATCCAGGAGCGCTGGAAGTGTGACGGAGACAACGATTGCCTGGACAACAGTGATGAGGCCCCAGCCCTCTGCCATCAGCACACCTG
CCCCTCGGACCGATTCAAGTGCGAGAACAACCGGTGCATCCCCAACCGCTGGCTCTGCGACGGGGACAATGACTGTGGGAACAGTGAAGA
TGAGTCCAATGCCACTTGTTCAGCCCGCACCTGCCCCCCCAACCAGTTCTCCTGTGCCAGTGGCCGCTGCATCCCCATCTCCTGGACGTG
TGATCTGGATGACGACTGTGGGGACCGCTCTGATGAGTCTGCTTCGTGTGCCTATCCCACCTGCTTCCCCCTGACTCAGTTTACCTGCAA
CAATGGCAGATGTATCAACATCAACTGGAGATGCGACAATGACAATGACTGTGGGGACAACAGTGACGAAGCCGGCTGCAGCCACTCCTG
TTCTAGCACCCAGTTCAAGTGCAACAGCGGGCGTTGCATCCCCGAGCACTGGACCTGCGATGGGGACAATGACTGCGGAGACTACAGTGA
TGAGACACACGCCAACTGCACCAACCAGGCCACGAGGCCCCCTGGTGGCTGCCACACTGATGAGTTCCAGTGCCGGCTGGATGGACTATG
CATCCCCCTGCGGTGGCGCTGCGATGGGGACACTGACTGCATGGACTCCAGCGATGAGAAGAGCTGTGAGGGAGTGACCCACGTCTGCGA
TCCCAGTGTCAAGTTTGGCTGCAAGGACTCAGCTCGGTGCATCAGCAAAGCGTGGGTGTGTGATGGCGACAATGACTGTGAGGATAACTC
GGACGAGGAGAACTGCGAGTCCCTGGCCTGCAGGCCACCCTCGCACCCTTGTGCCAACAACACCTCAGTCTGCCTGCCCCCTGACAAGCT
GTGTGATGGCAACGACGACTGTGGCGACGGCTCAGATGAGGGCGAGCTCTGCGACCAGTGCTCTCTGAATAACGGTGGCTGCAGCCACAA
CTGCTCAGTGGCACCTGGCGAAGGCATTGTGTGTTCCTGCCCTCTGGGCATGGAGCTGGGGCCCGACAACCACACCTGCCAGATCCAGAG
CTACTGTGCCAAGCATCTCAAATGCAGCCAAAAGTGCGACCAGAACAAGTTCAGCGTGAAGTGCTCCTGCTACGAGGGCTGGGTCCTGGA
ACCTGACGGCGAGAGCTGCCGCAGCCTGGACCCCTTCAAGCCGTTCATCATTTTCTCCAACCGCCATGAAATCCGGCGCATCGATCTTCA
CAAAGGAGACTACAGCGTCCTGGTGCCCGGCCTGCGCAACACCATCGCCCTGGACTTCCACCTCAGCCAGAGCGCCCTCTACTGGACCGA
CGTGGTGGAGGACAAGATCTACCGCGGGAAGCTGCTGGACAACGGAGCCCTGACTAGTTTCGAGGTGGTGATTCAGTATGGCCTGGCCAC
ACCCGAGGGCCTGGCTGTAGACTGGATTGCAGGCAACATCTACTGGGTGGAGAGTAACCTGGATCAGATCGAGGTGGCCAAGCTGGATGG
GACCCTCCGGACCACCCTGCTGGCCGGTGACATTGAGCACCCAAGGGCAATCGCACTGGATCCCCGGGATGGGATCCTGTTTTGGACAGA
CTGGGATGCCAGCCTGCCCCGCATTGAGGCAGCCTCCATGAGTGGGGCTGGGCGCCGCACCGTGCACCGGGAGACCGGCTCTGGGGGCTG
GCCCAACGGGCTCACCGTGGACTACCTGGAGAAGCGCATCCTTTGGATTGACGCCAGGTCAGATGCCATTTACTCAGCCCGTTACGACGG
CTCTGGCCACATGGAGGTGCTTCGGGGACACGAGTTCCTGTCGCACCCGTTTGCAGTGACGCTGTACGGGGGGGAGGTCTACTGGACTGA
CTGGCGAACAAACACACTGGCTAAGGCCAACAAGTGGACCGGCCACAATGTCACCGTGGTACAGAGGACCAACACCCAGCCCTTTGACCT
GCAGGTGTACCACCCCTCCCGCCAGCCCATGGCTCCCAATCCCTGTGAGGCCAATGGGGGCCAGGGCCCCTGCTCCCACCTGTGTCTCAT
CAACTACAACCGGACCGTGTCCTGCGCCTGCCCCCACCTCATGAAGCTCCACAAGGACAACACCACCTGCTATGAGTTTAAGAAGTTCCT
GCTGTACGCACGTCAGATGGAGATCCGAGGTGTGGACCTGGATGCTCCCTACTACAACTACATCATCTCCTTCACGGTGCCCGACATCGA
CAACGTCACAGTGCTAGACTACGATGCCCGCGAGCAGCGTGTGTACTGGTCTGACGTGCGGACACAGGCCATCAAGCGGGCCTTCATCAA
CGGCACAGGCGTGGAGACAGTCGTCTCTGCAGACTTGCCAAATGCCCACGGGCTGGCTGTGGACTGGGTCTCCCGAAACCTGTTCTGGAC
AAGCTATGACACCAATAAGAAGCAGATCAATGTGGCCCGGCTGGATGGCTCCTTCAAGAACGCAGTGGTGCAGGGCCTGGAGCAGCCCCA
TGGCCTTGTCGTCCACCCTCTGCGTGGGAAGCTCTACTGGACCGATGGTGACAACATCAGCATGGCCAACATGGATGGCAGCAATCGCAC
CCTGCTCTTCAGTGGCCAGAAGGGCCCCGTGGGCCTGGCTATTGACTTCCCTGAAAGCAAACTCTACTGGATCAGCTCCGGGAACCATAC
CATCAACCGCTGCAACCTGGATGGGAGTGGGCTGGAGGTCATCGATGCCATGCGGAGCCAGCTGGGCAAGGCCACCGCCCTGGCCATCAT
GGGGGACAAGCTGTGGTGGGCTGATCAGGTGTCGGAAAAGATGGGCACATGCAGCAAGGCTGACGGCTCGGGCTCCGTGGTCCTTCGGAA
CAGCACCACCCTGGTGATGCACATGAAGGTCTATGACGAGAGCATCCAGCTGGACCATAAGGGCACCAACCCCTGCAGTGTCAACAACGG
TGACTGCTCCCAGCTCTGCCTGCCCACGTCAGAGACGACCCGCTCCTGCATGTGCACAGCCGGCTATAGCCTCCGGAGTGGCCAGCAGGC
CTGCGAGGGCGTAGGTTCCTTTCTCCTGTACTCTGTGCATGAGGGAATCAGGGGAATTCCCCTGGATCCCAATGACAAGTCAGATGCCCT
GGTCCCAGTGTCCGGGACCTCGCTGGCTGTCGGCATCGACTTCCACGCTGAAAATGACACCATCTACTGGGTGGACATGGGCCTGAGCAC
GATCAGCCGGGCCAAGCGGGACCAGACGTGGCGTGAAGACGTGGTGACCAATGGCATTGGCCGTGTGGAGGGCATTGCAGTGGACTGGAT
CGCAGGCAACATCTACTGGACAGACCAGGGCTTTGATGTCATCGAGGTCGCCCGGCTCAATGGCTCCTTCCGCTACGTGGTGATCTCCCA
GGGTCTAGACAAGCCCCGGGCCATCACCGTCCACCCGGAGAAAGGGTACTTGTTCTGGACTGAGTGGGGTCAGTATCCGCGTATTGAGCG
GTCTCGGCTAGATGGCACGGAGCGTGTGGTGCTGGTCAACGTCAGCATCAGCTGGCCCAACGGCATCTCAGTGGACTACCAGGATGGGAA
GCTGTACTGGTGCGATGCACGGACAGACAAGATTGAACGGATCGACCTGGAGACAGGTGAGAACCGCGAGGTGGTTCTGTCCAGCAACAA
CATGGACATGTTTTCAGTGTCTGTGTTTGAGGATTTCATCTACTGGAGTGACAGGACTCATGCCAACGGCTCTATCAAGCGCGGGAGCAA
AGACAATGCCACAGACTCCGTGCCCCTGCGAACCGGCATCGGCGTCCAGCTTAAAGACATCAAAGTCTTCAACCGGGACCGGCAGAAAGG
CACCAACGTGTGCGCGGTGGCCAATGGCGGGTGCCAGCAGCTGTGCCTGTACCGGGGCCGTGGGCAGCGGGCCTGCGCCTGTGCCCACGG
GATGCTGGCTGAAGACGGAGCATCGTGCCGCGAGTATGCCGGCTACCTGCTCTACTCAGAGCGCACCATTCTCAAGAGTATCCACCTGTC
GGATGAGCGCAACCTCAATGCGCCCGTGCAGCCCTTCGAGGACCCTGAGCACATGAAGAACGTCATCGCCCTGGCCTTTGACTACCGGGC
AGGCACCTCTCCGGGCACCCCCAATCGCATCTTCTTCAGCGACATCCACTTTGGGAACATCCAACAGATCAACGACGATGGCTCCAGGAG
GATCACCATTGTGGAAAACGTGGGCTCCGTGGAAGGCCTGGCCTATCACCGTGGCTGGGACACTCTCTATTGGACAAGCTACACGACATC
CACCATCACGCGCCACACAGTGGACCAGACCCGCCCAGGGGCCTTCGAGCGTGAGACCGTCATCACTATGTCTGGAGATGACCACCCACG
GGCCTTCGTTTTGGACGAGTGCCAGAACCTCATGTTCTGGACCAACTGGAATGAGCAGCATCCCAGCATCATGCGGGCGGCGCTCTCGGG
AGCCAATGTCCTGACCCTTATCGAGAAGGACATCCGTACCCCCAATGGCCTGGCCATCGACCACCGTGCCGAGAAGCTCTACTTCTCTGA
CGCCACCCTGGACAAGATCGAGCGGTGCGAGTATGACGGCTCCCACCGCTATGTGATCCTAAAGTCAGAGCCTGTCCACCCCTTCGGGCT
GGCCGTGTATGGGGAGCACATTTTCTGGACTGACTGGGTGCGGCGGGCAGTGCAGCGGGCCAACAAGCACGTGGGCAGCAACATGAAGCT
GCTGCGCGTGGACATCCCCCAGCAGCCCATGGGCATCATCGCCGTGGCCAACGACACCAACAGCTGTGAACTCTCTCCATGCCGAATCAA
CAACGGTGGCTGCCAGGACCTGTGTCTGCTCACTCACCAGGGCCATGTCAACTGCTCATGCCGAGGGGGCCGAATCCTCCAGGATGACCT
CACCTGCCGAGCGGTGAATTCCTCTTGCCGAGCACAAGATGAGTTTGAGTGTGCCAATGGCGAGTGCATCAACTTCAGCCTGACCTGCGA
CGGCGTCCCCCACTGCAAGGACAAGTCCGATGAGAAGCCATCCTACTGCAACTCCCGCCGCTGCAAGAAGACTTTCCGGCAGTGCAGCAA
TGGGCGCTGTGTGTCCAACATGCTGTGGTGCAACGGGGCCGACGACTGTGGGGATGGCTCTGACGAGATCCCTTGCAACAAGACAGCCTG
TGGTGTGGGCGAGTTCCGCTGCCGGGACGGGACCTGCATCGGGAACTCCAGCCGCTGCAACCAGTTTGTGGATTGTGAGGACGCCTCAGA
TGAGATGAACTGCAGTGCCACCGACTGCAGCAGCTACTTCCGCCTGGGCGTGAAGGGCGTGCTCTTCCAGCCCTGCGAGCGGACCTCACT
CTGCTACGCACCCAGCTGGGTGTGTGATGGCGCCAATGACTGTGGGGACTACAGTGATGAGCGCGACTGCCCAGGTGTGAAACGCCCCAG
ATGCCCTCTGAATTACTTCGCCTGCCCTAGTGGGCGCTGCATCCCCATGAGCTGGACGTGTGACAAAGAGGATGACTGTGAACATGGCGA
GGACGAGACCCACTGCAACAAGTTCTGCTCAGAGGCCCAGTTTGAGTGCCAGAACCATCGCTGCATCTCCAAGCAGTGGCTGTGTGACGG
CAGCGATGACTGTGGGGATGGCTCAGACGAGGCTGCTCACTGTGAAGGCAAGACGTGCGGCCCCTCCTCCTTCTCCTGCCCTGGCACCCA
CGTGTGCGTCCCCGAGCGCTGGCTCTGTGACGGTGACAAAGACTGTGCTGATGGTGCAGACGAGAGCATCGCAGCTGGTTGCTTGTACAA
CAGCACTTGTGACGACCGTGAGTTCATGTGCCAGAACCGCCAGTGCATCCCCAAGCACTTCGTGTGTGACCACGACCGTGACTGTGCAGA
TGGCTCTGATGAGTCCCCCGAGTGTGAGTACCCGACCTGCGGCCCCAGTGAGTTCCGCTGTGCCAATGGGCGCTGTCTGAGCTCCCGCCA
GTGGGAGTGTGATGGCGAGAATGACTGCCACGACCAGAGTGACGAGGCTCCCAAGAACCCACACTGCACCAGCCAAGAGCACAAGTGCAA
TGCCTCGTCACAGTTCCTGTGCAGCAGTGGGCGCTGTGTGGCTGAGGCACTGCTCTGCAACGGCCAGGATGACTGTGGCGACAGCTCGGA
CGAGCGTGGCTGCCACATCAATGAGTGTCTCAGCCGCAAGCTCAGTGGCTGCAGCCAGGACTGTGAGGACCTCAAGATCGGCTTCAAGTG
CCGCTGTCGCCCTGGCTTCCGGCTGAAGGACGACGGCCGGACGTGTGCTGATGTGGACGAGTGCAGCACCACCTTCCCCTGCAGCCAGCG
CTGCATCAACACTCATGGCAGCTATAAGTGTCTGTGTGTGGAGGGCTATGCACCCCGCGGCGGCGACCCCCACAGCTGCAAGGCTGTGAC
TGACGAGGAACCGTTTCTGATCTTCGCCAACCGGTACTACCTGCGCAAGCTCAACCTGGACGGGTCCAACTACACGTTACTTAAGCAGGG
CCTGAACAACGCCGTTGCCTTGGATTTTGACTACCGAGAGCAGATGATCTACTGGACAGATGTGACCACCCAGGGCAGCATGATCCGAAG
GATGCACCTTAACGGGAGCAATGTGCAGGTCCTACACCGTACAGGCCTCAGCAACCCCGATGGGCTGGCTGTGGACTGGGTGGGTGGCAA
CCTGTACTGGTGCGACAAAGGCCGGGACACCATCGAGGTGTCCAAGCTCAATGGGGCCTATCGGACGGTGCTGGTCAGCTCTGGCCTCCG
TGAGCCCAGGGCTCTGGTGGTGGATGTGCAGAATGGGTACCTGTACTGGACAGACTGGGGTGACCATTCACTGATCGGCCGCATCGGCAT
GGATGGGTCCAGCCGCAGCGTCATCGTGGACACCAAGATCACATGGCCCAATGGCCTGACGCTGGACTATGTCACTGAGCGCATCTACTG
GGCCGACGCCCGCGAGGACTACATTGAATTTGCCAGCCTGGATGGCTCCAATCGCCACGTTGTGCTGAGCCAGGACATCCCGCACATCTT
TGCACTGACCCTGTTTGAGGACTACGTCTACTGGACCGACTGGGAAACAAAGTCCATTAACCGAGCCCACAAGACCACGGGCACCAACAA
AACGCTCCTCATCAGCACGCTGCACCGGCCCATGGACCTGCATGTCTTCCATGCCCTGCGCCAGCCAGACGTGCCCAATCACCCCTGCAA
GGTCAACAATGGTGGCTGCAGCAACCTGTGCCTGCTGTCCCCCGGGGGAGGGCACAAATGTGCCTGCCCCACCAACTTCTACCTGGGCAG
CGATGGGCGCACCTGTGTGTCCAACTGCACGGCTAGCCAGTTTGTATGCAAGAACGACAAGTGCATCCCCTTCTGGTGGAAGTGTGACAC
CGAGGACGACTGCGGGGACCACTCAGACGAGCCCCCGGACTGCCCTGAGTTCAAGTGCCGGCCCGGACAGTTCCAGTGCTCCACAGGTAT
CTGCACAAACCCTGCCTTCATCTGCGATGGCGACAATGACTGCCAGGACAACAGTGACGAGGCCAACTGTGACATCCACGTCTGCTTGCC
CAGTCAGTTCAAATGCACCAACACCAACCGCTGTATTCCCGGCATCTTCCGCTGCAATGGGCAGGACAACTGCGGAGATGGGGAGGATGA
GAGGGACTGCCCCGAGGTGACCTGCGCCCCCAACCAGTTCCAGTGCTCCATTACCAAACGGTGCATCCCCCGGGTCTGGGTCTGCGACCG
GGACAATGACTGTGTGGATGGCAGTGATGAGCCCGCCAACTGCACCCAGATGACCTGTGGTGTGGACGAGTTCCGCTGCAAGGATTCGGG
CCGCTGCATCCCAGCGCGTTGGAAGTGTGACGGAGAGGATGACTGTGGGGATGGCTCGGATGAGCCCAAGGAAGAGTGTGATGAACGCAC
CTGTGAGCCATACCAGTTCCGCTGCAAGAACAACCGCTGCGTGCCCGGCCGCTGGCAGTGCGACTACGACAACGATTGCGGTGACAACTC
CGATGAAGAGAGCTGCACCCCTCGGCCCTGCTCCGAGAGTGAGTTCTCCTGTGCCAACGGCCGCTGCATCGCGGGGCGCTGGAAATGCGA
TGGAGACCACGACTGCGCGGACGGCTCGGACGAGAAAGACTGCACCCCCCGCTGTGACATGGACCAGTTCCAGTGCAAGAGCGGCCACTG
CATCCCCCTGCGCTGGCGCTGTGACGCAGACGCCGACTGCATGGACGGCAGCGACGAGGAGGCCTGCGGCACTGGCGTGCGGACCTGCCC
CCTGGACGAGTTCCAGTGCAACAACACCTTGTGCAAGCCGCTGGCCTGGAAGTGCGATGGCGAGGATGACTGTGGGGACAACTCAGATGA
GAACCCCGAGGAGTGTGCCCGGTTCGTGTGCCCTCCCAACCGGCCCTTCCGTTGCAAGAATGACCGCGTCTGTCTGTGGATCGGGCGCCA
ATGCGATGGCACGGACAACTGTGGGGATGGGACTGATGAAGAGGACTGTGAGCCCCCCACAGCCCACACCACCCACTGCAAAGACAAGAA
GGAGTTTCTGTGCCGGAACCAGCGCTGCCTCTCCTCCTCCCTGCGCTGCAACATGTTCGATGACTGCGGGGACGGCTCTGACGAGGAGGA
CTGCAGCATCGACCCCAAGCTGACCAGCTGCGCCACCAATGCCAGCATCTGTGGGGACGAGGCACGCTGCGTGCGCACCGAGAAAGCGGC
CTACTGTGCCTGCCGCTCGGGCTTCCACACCGTGCCCGGCCAGCCCGGATGCCAAGACATCAACGAGTGCCTGCGCTTCGGCACCTGCTC
CCAGCTCTGCAACAACACCAAGGGCGGCCACCTCTGCAGCTGCGCTCGGAACTTCATGAAGACGCACAACACCTGCAAGGCCGAAGGCTC
TGAGTACCAGGTCCTGTACATCGCTGATGACAATGAGATCCGCAGCCTGTTCCCCGGCCACCCCCATTCGGCTTACGAGCAGGCATTCCA
GGGTGACGAGAGTGTCCGCATTGATGCTATGGATGTCCATGTCAAGGCTGGCCGTGTCTATTGGACCAACTGGCACACGGGCACCATCTC
CTACCGCAGCCTGCCACCTGCTGCGCCTCCTACCACTTCCAACCGCCACCGGCGACAGATTGACCGGGGTGTCACCCACCTCAACATTTC
AGGGCTGAAGATGCCCAGAGGCATCGCCATCGACTGGGTGGCCGGAAACGTGTACTGGACCGACTCGGGCCGAGATGTGATTGAGGTGGC
GCAGATGAAGGGCGAGAACCGCAAGACGCTCATCTCGGGCATGATTGACGAGCCCCACGCCATTGTGGTGGACCCACTGAGGGGGACCAT
GTACTGGTCAGACTGGGGCAACCACCCCAAGATTGAGACGGCAGCGATGGATGGGACGCTTCGGGAGACACTGGTGCAGGACAACATTCA
GTGGCCCACAGGCCTGGCCGTGGATTATCACAATGAGCGGCTGTACTGGGCAGACGCCAAGCTTTCAGTCATCGGCAGCATCCGGCTCAA
TGGCACGGACCCCATTGTGGCTGCTGACAGCAAACGAGGCCTAAGTCACCCCTTCAGCATCGACGTCTTTGAGGATTACATCTATGGTGT
CACCTACATCAATAATCGTGTCTTCAAGATCCATAAGTTTGGCCACAGCCCCTTGGTCAACCTGACAGGGGGCCTGAGCCACGCCTCTGA
CGTGGTCCTTTACCATCAGCACAAGCAGCCCGAAGTGACCAACCCATGTGACCGCAAGAAATGCGAGTGGCTCTGCCTGCTGAGCCCCAG
TGGGCCTGTCTGCACCTGTCCCAATGGGAAGCGGCTGGACAACGGCACATGCGTGCCTGTGCCCTCTCCAACGCCCCCCCCAGATGCTCC
CCGGCCTGGAACCTGTAACCTGCAGTGCTTCAACGGTGGCAGCTGTTTCCTCAATGCACGGAGGCAGCCCAAGTGCCGCTGCCAACCCCG
CTACACGGGTGACAAGTGTGAACTGGACCAGTGCTGGGAGCACTGTCGCAATGGGGGCACCTGTGCTGCCTCCCCCTCTGGCATGCCCAC
GTGCCGGTGCCCCACGGGCTTCACGGGCCCCAAATGCACCCAGCAGGTGTGTGCGGGCTACTGTGCCAACAACAGCACCTGCACTGTCAA
CCAGGGCAACCAGCCCCAGTGCCGATGCCTACCCGGCTTCCTGGGCGACCGCTGCCAGTACCAGCTGATGGTGGCTGACCGGCGCCAGAA
GCGAGAGATTCGGCAGCTGGAACAGGAACTGCATAAGTGGCAGGTGCTAGTGGACAGCATCACAGGCATGAGCTCTCCGGACTTCGACAA
CCAGACACTGGCAGTGCTGCGGGGCCGCATGGTGCGGTACCTGATGCGCTCGCGTGAGATCACCCTGGGCAGAGCAACCAAGGATAACCA
GATTGATGTGGACCTGTCTCTGGAGGGTCCGGCCTGGAAGATATCCCGGAAACAAGGTGTCATCAAGCTGAAGAACAACGGTGATTTCTT
CATTGCCAATGAGGGTCGACGGCCCATCTACATCGATGGACGGCCGGTGCTCTGTGGCTCCAAATGGCGCCTCAGCAACAACTCTGTGGT
GGAGATCGCCAGCCTGCGATTCGTCTTCCTTATCAACCAGGACCTCATTGCCCTCATCAGGGCTGAGGCTGCCAAGATCACACCACAGTG
AGGAGTGGTGGCAGGACTCGTGGGCCCTCTCCGGCCTGTTTCCCCTGCCACTCCAGCCCCCTTGAGCTGGGAACTCAGGCTCCTGGAAAA
ACCTGGGCAGTGGGAGGCTCAGCTGCGGGCCATTGATTTGAGCCTTTGAGGGAGGATAGGGCTGGCCTTTGTGAAGCCAGCAGAGGCTGA
GAACCTCAGGCTTCCCTAGATCCAGAGCCCCTCCCCATCTTCCTCTCTCTAAAAACAACCCTACCCCCCATTGCCACCTTCACTCCTGTG

>49750_49750_3_LRP1-MCRS1_LRP1_chr12_57604662_ENST00000243077_MCRS1_chr12_49953604_ENST00000550165_length(amino acids)=4472AA_BP=4314
MLLASAHTMLTPPLLLLLPLLSALVAAAIDAPKTCSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGT
ELCVPMSRLCNGVQDCMDGSDEGPHCRELQGNCSRLGCQHHCVPTLDGPTCYCNSSFQLQADGKTCKDFDECSVYGTCSQLCTNTDGSFI
CGCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAQVSTITPTSTRQTTAMDFSYANETVCWVHVGDSAAQTQLKCARMP
GLKGFVDEHTINISLSLHHVEQMAIDWLTGNFYFVDDIDDRIFVCNRNGDTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCD
MDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKGRQTIIQGILIEHLYGLTVFENYLYATNSDNANAQQKTSVIRV
NRFNSTEYQVVTRVDKGGALHIYHQRRQPRVRSHACENDQYGKPGGCSDICLLANSHKARTCRCRSGFSLGSDGKSCKKPEHELFLVYGK
GRPGIIRGMDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGVAVDWMGDNLYWTDDG
PKKTISVARLEKAAQTRKTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSRRGRLERAWMDGSHRDIFVTSKTVLWPNGLSLDIPAGR
LYWVDAFYDRIETILLNGTDRKIVYEGPELNHAFGLCHHGNYLFWTEYRSGSVYRLERGVGGAPPTVTLLRSERPPIFEIRMYDAQQQQV
GTNKCRVNNGGCSSLCLATPGSRQCACAEDQVLDADGVTCLANPSYVPPPQCQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQ
HTCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQF
TCNNGRCININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLD
GLCIPLRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDEENCESLACRPPSHPCANNTSVCLPP
DKLCDGNDDCGDGSDEGELCDQCSLNNGGCSHNCSVAPGEGIVCSCPLGMELGPDNHTCQIQSYCAKHLKCSQKCDQNKFSVKCSCYEGW
VLEPDGESCRSLDPFKPFIIFSNRHEIRRIDLHKGDYSVLVPGLRNTIALDFHLSQSALYWTDVVEDKIYRGKLLDNGALTSFEVVIQYG
LATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTLRTTLLAGDIEHPRAIALDPRDGILFWTDWDASLPRIEAASMSGAGRRTVHRETGS
GGWPNGLTVDYLEKRILWIDARSDAIYSARYDGSGHMEVLRGHEFLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTVVQRTNTQP
FDLQVYHPSRQPMAPNPCEANGGQGPCSHLCLINYNRTVSCACPHLMKLHKDNTTCYEFKKFLLYARQMEIRGVDLDAPYYNYIISFTVP
DIDNVTVLDYDAREQRVYWSDVRTQAIKRAFINGTGVETVVSADLPNAHGLAVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVVQGLE
QPHGLVVHPLRGKLYWTDGDNISMANMDGSNRTLLFSGQKGPVGLAIDFPESKLYWISSGNHTINRCNLDGSGLEVIDAMRSQLGKATAL
AIMGDKLWWADQVSEKMGTCSKADGSGSVVLRNSTTLVMHMKVYDESIQLDHKGTNPCSVNNGDCSQLCLPTSETTRSCMCTAGYSLRSG
QQACEGVGSFLLYSVHEGIRGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWREDVVTNGIGRVEGIAV
DWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQYPRIERSRLDGTERVVLVNVSISWPNGISVDYQ
DGKLYWCDARTDKIERIDLETGENREVVLSSNNMDMFSVSVFEDFIYWSDRTHANGSIKRGSKDNATDSVPLRTGIGVQLKDIKVFNRDR
QKGTNVCAVANGGCQQLCLYRGRGQRACACAHGMLAEDGASCREYAGYLLYSERTILKSIHLSDERNLNAPVQPFEDPEHMKNVIALAFD
YRAGTSPGTPNRIFFSDIHFGNIQQINDDGSRRITIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQTRPGAFERETVITMSGDD
HPRAFVLDECQNLMFWTNWNEQHPSIMRAALSGANVLTLIEKDIRTPNGLAIDHRAEKLYFSDATLDKIERCEYDGSHRYVILKSEPVHP
FGLAVYGEHIFWTDWVRRAVQRANKHVGSNMKLLRVDIPQQPMGIIAVANDTNSCELSPCRINNGGCQDLCLLTHQGHVNCSCRGGRILQ
DDLTCRAVNSSCRAQDEFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADDCGDGSDEIPCNK
TACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVK
RPRCPLNYFACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCP
GTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCANGRCLS
SRQWECDGENDCHDQSDEAPKNPHCTSQEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSDERGCHINECLSRKLSGCSQDCEDLKIG
FKCRCRPGFRLKDDGRTCADVDECSTTFPCSQRCINTHGSYKCLCVEGYAPRGGDPHSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLL
KQGLNNAVALDFDYREQMIYWTDVTTQGSMIRRMHLNGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVSS
GLREPRALVVDVQNGYLYWTDWGDHSLIGRIGMDGSSRSVIVDTKITWPNGLTLDYVTERIYWADAREDYIEFASLDGSNRHVVLSQDIP
HIFALTLFEDYVYWTDWETKSINRAHKTTGTNKTLLISTLHRPMDLHVFHALRQPDVPNHPCKVNNGGCSNLCLLSPGGGHKCACPTNFY
LGSDGRTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHV
CLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCK
DSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRW
KCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDN
SDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSD
EEDCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRSGFHTVPGQPGCQDINECLRFGTCSQLCNNTKGGHLCSCARNFMKTHNTCKA
EGSEYQVLYIADDNEIRSLFPGHPHSAYEQAFQGDESVRIDAMDVHVKAGRVYWTNWHTGTISYRSLPPAAPPTTSNRHRRQIDRGVTHL
NISGLKMPRGIAIDWVAGNVYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQD
NIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPIVAADSKRGLSHPFSIDVFEDYIYGVTYINNRVFKIHKFGHSPLVNLTGGLSH
ASDVVLYHQHKQPEVTNPCDRKKCEWLCLLSPSGPVCTCPNGKRLDNGTCVPVPSPTPPPDAPRPGTCNLQCFNGGSCFLNARRQPKCRC
QPRYTGDKCELDQCWEHCRNGGTCAASPSGMPTCRCPTGFTGPKCTQQVCAGYCANNSTCTVNQGNQPQCRCLPGFLGDRCQYQLMVADR
RQKREIRQLEQELHKWQVLVDSITGMSSPDFDNQTLAVLRGRMVRYLMRSREITLGRATKDNQIDVDLSLEGPAWKISRKQGVIKLKNNG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for LRP1-MCRS1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneLRP1chr12:57604662chr12:49953604ENST00000243077-83894445_45444305.3333333333334545.0MAFB


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LRP1-MCRS1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LRP1-MCRS1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource