FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:LSM14A-DCTN2 (FusionGDB2 ID:50183)

Fusion Gene Summary for LSM14A-DCTN2

check button Fusion gene summary
Fusion gene informationFusion gene name: LSM14A-DCTN2
Fusion gene ID: 50183
HgeneTgene
Gene symbol

LSM14A

DCTN2

Gene ID

26065

10540

Gene nameLSM14A mRNA processing body assembly factordynactin subunit 2
SynonymsC19orf13|FAM61A|RAP55|RAP55ADCTN50|DYNAMITIN|HEL-S-77|RBP50
Cytomap

19q13.11

12q13.3

Type of geneprotein-codingprotein-coding
Descriptionprotein LSM14 homolog ALSM14 homolog ALSM14A, SCD6 homolog ARNA-associated protein 55RNA-associated protein 55AalphaSNBPfamily with sequence similarity 61, member AhRAP55hRAP55Aprotein SCD6 homologputative alpha-synuclein-binding proteindynactin subunit 250 kDa dynein-associated polypeptidedynactin 2 (p50)dynactin complex 50 kDa subunitepididymis secretory protein Li 77epididymis secretory sperm binding proteinp50 dynamitin
Modification date2020032720200313
UniProtAcc

Q8ND56

Q13561

Ensembl transtripts involved in fusion geneENST00000433627, ENST00000540746, 
ENST00000544216, 		ENST00000551400, 
ENST00000434715, ENST00000537439, 
ENST00000543672, ENST00000548249, 
Fusion gene scores* DoF score18 X 10 X 10=18007 X 3 X 6=126
# samples 247
** MAII scorelog2(24/1800*10)=-2.90689059560852
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/126*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LSM14A [Title/Abstract] AND DCTN2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLSM14A(34687668)-DCTN2(57925890), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneLSM14A

GO:0033962

cytoplasmic mRNA processing body assembly

16484376


check buttonFusion gene breakpoints across LSM14A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DCTN2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABF686433LSM14Achr19

34687668

+DCTN2chr12

57925890

-


Top

Fusion Gene ORF analysis for LSM14A-DCTN2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000433627ENST00000551400LSM14Achr19

34687668

+DCTN2chr12

57925890

-
5CDS-intronENST00000540746ENST00000551400LSM14Achr19

34687668

+DCTN2chr12

57925890

-
5CDS-intronENST00000544216ENST00000551400LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000433627ENST00000434715LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000433627ENST00000537439LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000433627ENST00000543672LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000433627ENST00000548249LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000540746ENST00000434715LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000540746ENST00000537439LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000540746ENST00000543672LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000540746ENST00000548249LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000544216ENST00000434715LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000544216ENST00000537439LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000544216ENST00000543672LSM14Achr19

34687668

+DCTN2chr12

57925890

-
In-frameENST00000544216ENST00000548249LSM14Achr19

34687668

+DCTN2chr12

57925890

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000540746LSM14Achr1934687668+ENST00000548249DCTN2chr1257925890-129953385711208
ENST00000540746LSM14Achr1934687668+ENST00000537439DCTN2chr1257925890-109053385711208
ENST00000540746LSM14Achr1934687668+ENST00000434715DCTN2chr1257925890-109053385711208
ENST00000540746LSM14Achr1934687668+ENST00000543672DCTN2chr1257925890-109053385711208
ENST00000544216LSM14Achr1934687668+ENST00000548249DCTN2chr1257925890-125849244670208
ENST00000544216LSM14Achr1934687668+ENST00000537439DCTN2chr1257925890-104949244670208
ENST00000544216LSM14Achr1934687668+ENST00000434715DCTN2chr1257925890-104949244670208
ENST00000544216LSM14Achr1934687668+ENST00000543672DCTN2chr1257925890-104949244670208
ENST00000433627LSM14Achr1934687668+ENST00000548249DCTN2chr1257925890-125649042668208
ENST00000433627LSM14Achr1934687668+ENST00000537439DCTN2chr1257925890-104749042668208
ENST00000433627LSM14Achr1934687668+ENST00000434715DCTN2chr1257925890-104749042668208
ENST00000433627LSM14Achr1934687668+ENST00000543672DCTN2chr1257925890-104749042668208

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000540746ENST00000548249LSM14Achr1934687668+DCTN2chr1257925890-0.0020887850.99791116
ENST00000540746ENST00000537439LSM14Achr1934687668+DCTN2chr1257925890-0.0018097680.9981902
ENST00000540746ENST00000434715LSM14Achr1934687668+DCTN2chr1257925890-0.0018097680.9981902
ENST00000540746ENST00000543672LSM14Achr1934687668+DCTN2chr1257925890-0.0018097680.9981902
ENST00000544216ENST00000548249LSM14Achr1934687668+DCTN2chr1257925890-0.0022090280.99779093
ENST00000544216ENST00000537439LSM14Achr1934687668+DCTN2chr1257925890-0.0020128370.99798715
ENST00000544216ENST00000434715LSM14Achr1934687668+DCTN2chr1257925890-0.0020128370.99798715
ENST00000544216ENST00000543672LSM14Achr1934687668+DCTN2chr1257925890-0.0020128370.99798715
ENST00000433627ENST00000548249LSM14Achr1934687668+DCTN2chr1257925890-0.0019553060.9980447
ENST00000433627ENST00000537439LSM14Achr1934687668+DCTN2chr1257925890-0.0018396240.9981604
ENST00000433627ENST00000434715LSM14Achr1934687668+DCTN2chr1257925890-0.0018396240.9981604
ENST00000433627ENST00000543672LSM14Achr1934687668+DCTN2chr1257925890-0.0018396240.9981604

Top

Fusion Genomic Features for LSM14A-DCTN2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for LSM14A-DCTN2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:34687668/chr12:57925890)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LSM14A

Q8ND56

DCTN2

Q13561

FUNCTION: Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for translationally inactive mRNAs and protect them from degradation (PubMed:16484376, PubMed:17074753, PubMed:29510985). Acts as a repressor of mRNA translation (PubMed:29510985). May play a role in mitotic spindle assembly (PubMed:26339800). {ECO:0000269|PubMed:16484376, ECO:0000269|PubMed:17074753, ECO:0000269|PubMed:26339800, ECO:0000269|PubMed:29510985}.FUNCTION: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDCTN2chr19:34687668chr12:57925890ENST000004347151316379_399347407.0Coiled coilOntology_term=ECO:0000255
TgeneDCTN2chr19:34687668chr12:57925890ENST000005482491114379_399342402.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLSM14Achr19:34687668chr12:57925890ENST00000433627+311284_3201381040.0DomainDFDF
HgeneLSM14Achr19:34687668chr12:57925890ENST00000544216+310284_320138464.0DomainDFDF
HgeneLSM14Achr19:34687668chr12:57925890ENST00000433627+311361_3771381040.0MotifNote=FFD box
HgeneLSM14Achr19:34687668chr12:57925890ENST00000433627+311380_4001381040.0MotifNote=TFG box
HgeneLSM14Achr19:34687668chr12:57925890ENST00000544216+310361_377138464.0MotifNote=FFD box
HgeneLSM14Achr19:34687668chr12:57925890ENST00000544216+310380_400138464.0MotifNote=TFG box
TgeneDCTN2chr19:34687668chr12:57925890ENST000004347151316214_244347407.0Coiled coilOntology_term=ECO:0000255
TgeneDCTN2chr19:34687668chr12:57925890ENST00000434715131699_132347407.0Coiled coilOntology_term=ECO:0000255
TgeneDCTN2chr19:34687668chr12:57925890ENST000005482491114214_244342402.0Coiled coilOntology_term=ECO:0000255
TgeneDCTN2chr19:34687668chr12:57925890ENST00000548249111499_132342402.0Coiled coilOntology_term=ECO:0000255


Top

Fusion Gene Sequence for LSM14A-DCTN2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>50183_50183_1_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000433627_DCTN2_chr12_57925890_ENST00000434715_length(transcript)=1047nt_BP=490nt
CGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCGAGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCACC
CCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCGCTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCACC
GTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGACAGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACATT
ATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACCAAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTCAG
TCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTATGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTCCG
AGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCAGTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGATG
ATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCAGACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACTTT
GCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTTGGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTCTG
TTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCCCATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGTGG
GGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTGGTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATAAG
GACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCCTGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTTCT

>50183_50183_1_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000433627_DCTN2_chr12_57925890_ENST00000434715_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------
>50183_50183_2_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000433627_DCTN2_chr12_57925890_ENST00000537439_length(transcript)=1047nt_BP=490nt
CGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCGAGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCACC
CCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCGCTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCACC
GTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGACAGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACATT
ATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACCAAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTCAG
TCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTATGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTCCG
AGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCAGTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGATG
ATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCAGACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACTTT
GCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTTGGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTCTG
TTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCCCATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGTGG
GGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTGGTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATAAG
GACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCCTGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTTCT

>50183_50183_2_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000433627_DCTN2_chr12_57925890_ENST00000537439_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------
>50183_50183_3_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000433627_DCTN2_chr12_57925890_ENST00000543672_length(transcript)=1047nt_BP=490nt
CGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCGAGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCACC
CCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCGCTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCACC
GTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGACAGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACATT
ATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACCAAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTCAG
TCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTATGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTCCG
AGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCAGTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGATG
ATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCAGACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACTTT
GCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTTGGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTCTG
TTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCCCATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGTGG
GGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTGGTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATAAG
GACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCCTGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTTCT

>50183_50183_3_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000433627_DCTN2_chr12_57925890_ENST00000543672_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------
>50183_50183_4_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000433627_DCTN2_chr12_57925890_ENST00000548249_length(transcript)=1256nt_BP=490nt
CGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCGAGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCACC
CCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCGCTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCACC
GTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGACAGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACATT
ATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACCAAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTCAG
TCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTATGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTCCG
AGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCAGTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGATG
ATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCAGACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACTTT
GCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTTGGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTCTG
TTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCCCATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGTGG
GGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTGGTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATAAG
GACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCCTGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTTCT
GTGGCTGACTGTAATACTGTACAACTGTTTCTGACCATTAAATGCTGTTGTACTCTGTGTGGCCTCTGCTGTGTTTCCTGGGGAGGAAGC
AGCACTAGGATATAGATATTCATTCGTCATAACAGGCAATCTAAGCCACTCTATACTACAAGAGATGGATTTAAATTGTAACCTGTTCTT

>50183_50183_4_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000433627_DCTN2_chr12_57925890_ENST00000548249_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------
>50183_50183_5_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000540746_DCTN2_chr12_57925890_ENST00000434715_length(transcript)=1090nt_BP=533nt
ATGTTGGGTCTGAAGCGGCTGCTGTAGGCGCCGACGGAGCGAGCGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCG
AGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCACCCCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCG
CTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCACCGTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGAC
AGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACATTATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACC
AAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTCAGTCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTA
TGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTCCGAGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCA
GTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGATGATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCA
GACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACTTTGCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTT
GGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTCTGTTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCC
CATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGTGGGGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTG
GTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATAAGGACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCC
TGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTTCTGTGGCTGACTGTAATACTGTACAACTGTTTCTGACCATTAAATGCTG

>50183_50183_5_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000540746_DCTN2_chr12_57925890_ENST00000434715_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------
>50183_50183_6_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000540746_DCTN2_chr12_57925890_ENST00000537439_length(transcript)=1090nt_BP=533nt
ATGTTGGGTCTGAAGCGGCTGCTGTAGGCGCCGACGGAGCGAGCGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCG
AGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCACCCCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCG
CTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCACCGTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGAC
AGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACATTATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACC
AAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTCAGTCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTA
TGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTCCGAGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCA
GTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGATGATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCA
GACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACTTTGCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTT
GGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTCTGTTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCC
CATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGTGGGGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTG
GTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATAAGGACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCC
TGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTTCTGTGGCTGACTGTAATACTGTACAACTGTTTCTGACCATTAAATGCTG

>50183_50183_6_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000540746_DCTN2_chr12_57925890_ENST00000537439_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------
>50183_50183_7_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000540746_DCTN2_chr12_57925890_ENST00000543672_length(transcript)=1090nt_BP=533nt
ATGTTGGGTCTGAAGCGGCTGCTGTAGGCGCCGACGGAGCGAGCGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCG
AGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCACCCCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCG
CTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCACCGTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGAC
AGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACATTATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACC
AAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTCAGTCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTA
TGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTCCGAGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCA
GTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGATGATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCA
GACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACTTTGCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTT
GGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTCTGTTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCC
CATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGTGGGGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTG
GTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATAAGGACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCC
TGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTTCTGTGGCTGACTGTAATACTGTACAACTGTTTCTGACCATTAAATGCTG

>50183_50183_7_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000540746_DCTN2_chr12_57925890_ENST00000543672_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------
>50183_50183_8_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000540746_DCTN2_chr12_57925890_ENST00000548249_length(transcript)=1299nt_BP=533nt
ATGTTGGGTCTGAAGCGGCTGCTGTAGGCGCCGACGGAGCGAGCGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCG
AGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCACCCCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCG
CTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCACCGTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGAC
AGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACATTATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACC
AAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTCAGTCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTA
TGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTCCGAGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCA
GTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGATGATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCA
GACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACTTTGCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTT
GGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTCTGTTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCC
CATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGTGGGGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTG
GTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATAAGGACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCC
TGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTTCTGTGGCTGACTGTAATACTGTACAACTGTTTCTGACCATTAAATGCTG
TTGTACTCTGTGTGGCCTCTGCTGTGTTTCCTGGGGAGGAAGCAGCACTAGGATATAGATATTCATTCGTCATAACAGGCAATCTAAGCC
ACTCTATACTACAAGAGATGGATTTAAATTGTAACCTGTTCTTACCAAAGAACTAAATAAAAAATGAGTACAGAGCCAGAGCCAGAGTTT

>50183_50183_8_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000540746_DCTN2_chr12_57925890_ENST00000548249_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------
>50183_50183_9_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000544216_DCTN2_chr12_57925890_ENST00000434715_length(transcript)=1049nt_BP=492nt
AGCGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCGAGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCA
CCCCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCGCTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCA
CCGTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGACAGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACA
TTATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACCAAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTC
AGTCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTATGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTC
CGAGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCAGTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGA
TGATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCAGACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACT
TTGCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTTGGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTC
TGTTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCCCATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGT
GGGGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTGGTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATA
AGGACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCCTGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTT

>50183_50183_9_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000544216_DCTN2_chr12_57925890_ENST00000434715_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------
>50183_50183_10_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000544216_DCTN2_chr12_57925890_ENST00000537439_length(transcript)=1049nt_BP=492nt
AGCGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCGAGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCA
CCCCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCGCTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCA
CCGTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGACAGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACA
TTATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACCAAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTC
AGTCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTATGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTC
CGAGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCAGTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGA
TGATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCAGACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACT
TTGCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTTGGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTC
TGTTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCCCATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGT
GGGGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTGGTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATA
AGGACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCCTGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTT

>50183_50183_10_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000544216_DCTN2_chr12_57925890_ENST00000537439_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------
>50183_50183_11_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000544216_DCTN2_chr12_57925890_ENST00000543672_length(transcript)=1049nt_BP=492nt
AGCGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCGAGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCA
CCCCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCGCTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCA
CCGTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGACAGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACA
TTATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACCAAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTC
AGTCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTATGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTC
CGAGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCAGTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGA
TGATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCAGACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACT
TTGCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTTGGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTC
TGTTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCCCATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGT
GGGGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTGGTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATA
AGGACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCCTGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTT

>50183_50183_11_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000544216_DCTN2_chr12_57925890_ENST00000543672_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------
>50183_50183_12_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000544216_DCTN2_chr12_57925890_ENST00000548249_length(transcript)=1258nt_BP=492nt
AGCGGGCGTGCGGAGCGGGCGACAGTGGCGTGGGATCTGCCTCTCTGCGAGCAGCTGGGAGCGGCGGCGGCGGCGCCATGAGCGGGGGCA
CCCCTTACATCGGCAGCAAGATCAGCCTCATCTCCAAGGCGGAGATCCGCTACGAGGGCATCCTCTACACCATCGACACCGAAAACTCCA
CCGTAGCCCTTGCCAAAGTTCGATCCTTTGGTACAGAAGACAGACCGACAGATCGTCCAATACCACCTCGAGATGAAGTCTTTGAATACA
TTATATTCCGTGGGAGTGACATTAAAGACCTTACTGTTTGTGAGCCACCAAAACCACAGTGTTCTTTGCCTCAAGACCCAGCTATTGTTC
AGTCCTCACTAGGCTCATCGACTTCTTCATTCCAGTCCATGGGTTCTTATGGACCTTTCGGCAGGATGCCCACATACAGTCAGTTCAGTC
CGAGTTCCTTAGTTGGGCAGCAGTTTGGTGCTGTTGGTGTTGCCATGCAGTTTGGTCAGCTCCTGACACACTTGGATACCACCCAGCAGA
TGATTGCTAATTCCTTGAAGGACAATACCACCCTCTTGACCCAGGTGCAGACAACCATGCGTGAAAACCTGGCCACAGTTGAGGGGAACT
TTGCCAGCATTGATGAACGGATGAAGAAGCTGGGAAAGTGAGCACATTTGGGAGCTGGAGAACAGGGGTTATCCCTACCCCTGTGAACTC
TGTTAACAGCTTACATAGGGTTTCCCCTTTACTATAACTCTAGCATCCCCATCCCATTTGACACTGGGGGCAAGGGTTCTTCTTGCATGT
GGGGTTTATACCCCTCCCCTGATGAATACAGAGTGGTAGCTAGGGGTTGGTTATCATCAGAAGGTGGTCTCCCCTCAGGCCTGGGGGATA
AGGACGTGGGCCCAGCCACATGCCAACTCATGTCCAATACTGCTTTGCCTGGTGTGGGGAAGGATTGGGTCTTGTCCCCCAACACAGCTT
CTGTGGCTGACTGTAATACTGTACAACTGTTTCTGACCATTAAATGCTGTTGTACTCTGTGTGGCCTCTGCTGTGTTTCCTGGGGAGGAA
GCAGCACTAGGATATAGATATTCATTCGTCATAACAGGCAATCTAAGCCACTCTATACTACAAGAGATGGATTTAAATTGTAACCTGTTC

>50183_50183_12_LSM14A-DCTN2_LSM14A_chr19_34687668_ENST00000544216_DCTN2_chr12_57925890_ENST00000548249_length(amino acids)=208AA_BP=148
MRAAGSGGGGAMSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCE
PPKPQCSLPQDPAIVQSSLGSSTSSFQSMGSYGPFGRMPTYSQFSPSSLVGQQFGAVGVAMQFGQLLTHLDTTQQMIANSLKDNTTLLTQ

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for LSM14A-DCTN2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for LSM14A-DCTN2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for LSM14A-DCTN2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource