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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LSR-HDLBP (FusionGDB2 ID:50240)

Fusion Gene Summary for LSR-HDLBP

check button Fusion gene summary
Fusion gene informationFusion gene name: LSR-HDLBP
Fusion gene ID: 50240
HgeneTgene
Gene symbol

LSR

HDLBP

Gene ID

51599

3069

Gene namelipolysis stimulated lipoprotein receptorhigh density lipoprotein binding protein
SynonymsILDR3|LISCH7HBP|PRO2900|VGL
Cytomap

19q13.12

2q37.3

Type of geneprotein-codingprotein-coding
Descriptionlipolysis-stimulated lipoprotein receptorLISCH proteinimmunoglobulin-like domain containing receptor 3lipolysis-stimulated remnantliver-specific bHLH-Zip transcription factorvigilinHDL-binding protein
Modification date2020031320200313
UniProtAcc

Q86X29

Q00341

Ensembl transtripts involved in fusion geneENST00000347609, ENST00000354900, 
ENST00000360798, ENST00000361790, 
ENST00000427250, ENST00000602122, 
ENST00000597933, 		ENST00000476807, 
ENST00000310931, ENST00000391975, 
ENST00000391976, ENST00000427183, 
Fusion gene scores* DoF score10 X 6 X 6=36028 X 24 X 13=8736
# samples 1129
** MAII scorelog2(11/360*10)=-1.71049338280502
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(29/8736*10)=-4.91284805090492
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LSR [Title/Abstract] AND HDLBP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLSR(35758865)-HDLBP(242202277), # samples:1
Anticipated loss of major functional domain due to fusion event.LSR-HDLBP seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across LSR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across HDLBP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-CK-6746-01ALSRchr19

35758865

-HDLBPchr2

242202277

-


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Fusion Gene ORF analysis for LSR-HDLBP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000347609ENST00000476807LSRchr19

35758865

-HDLBPchr2

242202277

-
5CDS-intronENST00000354900ENST00000476807LSRchr19

35758865

-HDLBPchr2

242202277

-
5CDS-intronENST00000360798ENST00000476807LSRchr19

35758865

-HDLBPchr2

242202277

-
5CDS-intronENST00000361790ENST00000476807LSRchr19

35758865

-HDLBPchr2

242202277

-
5CDS-intronENST00000427250ENST00000476807LSRchr19

35758865

-HDLBPchr2

242202277

-
5CDS-intronENST00000602122ENST00000476807LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000347609ENST00000310931LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000347609ENST00000391975LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000347609ENST00000391976LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000347609ENST00000427183LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000360798ENST00000310931LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000360798ENST00000391975LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000360798ENST00000391976LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000360798ENST00000427183LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000361790ENST00000310931LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000361790ENST00000391975LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000361790ENST00000391976LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000361790ENST00000427183LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000427250ENST00000310931LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000427250ENST00000391975LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000427250ENST00000391976LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000427250ENST00000427183LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000602122ENST00000310931LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000602122ENST00000391975LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000602122ENST00000391976LSRchr19

35758865

-HDLBPchr2

242202277

-
Frame-shiftENST00000602122ENST00000427183LSRchr19

35758865

-HDLBPchr2

242202277

-
In-frameENST00000354900ENST00000310931LSRchr19

35758865

-HDLBPchr2

242202277

-
In-frameENST00000354900ENST00000391975LSRchr19

35758865

-HDLBPchr2

242202277

-
In-frameENST00000354900ENST00000391976LSRchr19

35758865

-HDLBPchr2

242202277

-
In-frameENST00000354900ENST00000427183LSRchr19

35758865

-HDLBPchr2

242202277

-
intron-3CDSENST00000597933ENST00000310931LSRchr19

35758865

-HDLBPchr2

242202277

-
intron-3CDSENST00000597933ENST00000391975LSRchr19

35758865

-HDLBPchr2

242202277

-
intron-3CDSENST00000597933ENST00000391976LSRchr19

35758865

-HDLBPchr2

242202277

-
intron-3CDSENST00000597933ENST00000427183LSRchr19

35758865

-HDLBPchr2

242202277

-
intron-intronENST00000597933ENST00000476807LSRchr19

35758865

-HDLBPchr2

242202277

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000354900LSRchr1935758865-ENST00000391976HDLBPchr2242202277-60032105561999647
ENST00000354900LSRchr1935758865-ENST00000310931HDLBPchr2242202277-60032105561999647
ENST00000354900LSRchr1935758865-ENST00000391975HDLBPchr2242202277-79512105561999647
ENST00000354900LSRchr1935758865-ENST00000427183HDLBPchr2242202277-57862105561999647

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000354900ENST00000391976LSRchr1935758865-HDLBPchr2242202277-0.029229570.9707704
ENST00000354900ENST00000310931LSRchr1935758865-HDLBPchr2242202277-0.029229570.9707704
ENST00000354900ENST00000391975LSRchr1935758865-HDLBPchr2242202277-0.018232920.9817671
ENST00000354900ENST00000427183LSRchr1935758865-HDLBPchr2242202277-0.028950470.9710496

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Fusion Genomic Features for LSR-HDLBP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for LSR-HDLBP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:35758865/chr2:242202277)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LSR

Q86X29

HDLBP

Q00341

FUNCTION: Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells (By similarity). {ECO:0000250}.FUNCTION: Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLSRchr19:35758865chr2:242202277ENST00000347609-99280_304626592.0Compositional biasNote=Cys-rich
HgeneLSRchr19:35758865chr2:242202277ENST00000354900-99280_304666631.0Compositional biasNote=Cys-rich
HgeneLSRchr19:35758865chr2:242202277ENST00000360798-88280_304616582.0Compositional biasNote=Cys-rich
HgeneLSRchr19:35758865chr2:242202277ENST00000361790-1010280_304683650.0Compositional biasNote=Cys-rich
HgeneLSRchr19:35758865chr2:242202277ENST00000602122-99280_304664630.0Compositional biasNote=Cys-rich
HgeneLSRchr19:35758865chr2:242202277ENST00000347609-9986_234626592.0DomainNote=Ig-like V-type
HgeneLSRchr19:35758865chr2:242202277ENST00000354900-9986_234666631.0DomainNote=Ig-like V-type
HgeneLSRchr19:35758865chr2:242202277ENST00000360798-8886_234616582.0DomainNote=Ig-like V-type
HgeneLSRchr19:35758865chr2:242202277ENST00000361790-101086_234683650.0DomainNote=Ig-like V-type
HgeneLSRchr19:35758865chr2:242202277ENST00000602122-9986_234664630.0DomainNote=Ig-like V-type
HgeneLSRchr19:35758865chr2:242202277ENST00000347609-991_259626592.0Topological domainExtracellular
HgeneLSRchr19:35758865chr2:242202277ENST00000347609-99281_649626592.0Topological domainCytoplasmic
HgeneLSRchr19:35758865chr2:242202277ENST00000354900-991_259666631.0Topological domainExtracellular
HgeneLSRchr19:35758865chr2:242202277ENST00000354900-99281_649666631.0Topological domainCytoplasmic
HgeneLSRchr19:35758865chr2:242202277ENST00000360798-881_259616582.0Topological domainExtracellular
HgeneLSRchr19:35758865chr2:242202277ENST00000360798-88281_649616582.0Topological domainCytoplasmic
HgeneLSRchr19:35758865chr2:242202277ENST00000361790-10101_259683650.0Topological domainExtracellular
HgeneLSRchr19:35758865chr2:242202277ENST00000361790-1010281_649683650.0Topological domainCytoplasmic
HgeneLSRchr19:35758865chr2:242202277ENST00000602122-991_259664630.0Topological domainExtracellular
HgeneLSRchr19:35758865chr2:242202277ENST00000602122-99281_649664630.0Topological domainCytoplasmic
HgeneLSRchr19:35758865chr2:242202277ENST00000347609-99260_280626592.0TransmembraneHelical
HgeneLSRchr19:35758865chr2:242202277ENST00000354900-99260_280666631.0TransmembraneHelical
HgeneLSRchr19:35758865chr2:242202277ENST00000360798-88260_280616582.0TransmembraneHelical
HgeneLSRchr19:35758865chr2:242202277ENST00000361790-1010260_280683650.0TransmembraneHelical
HgeneLSRchr19:35758865chr2:242202277ENST00000602122-99260_280664630.0TransmembraneHelical
TgeneHDLBPchr19:35758865chr2:242202277ENST000003109310281060_113401269.0DomainKH 13
TgeneHDLBPchr19:35758865chr2:242202277ENST000003109310281135_120901269.0DomainKH 14
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028158_22901269.0DomainKH 1
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028230_30201269.0DomainKH 2
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028303_37101269.0DomainKH 3
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028372_44201269.0DomainKH 4
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028443_51401269.0DomainKH 5
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028515_58801269.0DomainKH 6
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028589_66001269.0DomainKH 7
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028661_73401269.0DomainKH 8
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028735_80701269.0DomainKH 9
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028808_88001269.0DomainKH 10
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028881_97901269.0DomainKH 11
TgeneHDLBPchr19:35758865chr2:242202277ENST00000310931028980_105901269.0DomainKH 12
TgeneHDLBPchr19:35758865chr2:242202277ENST000003919750281060_113401269.0DomainKH 13
TgeneHDLBPchr19:35758865chr2:242202277ENST000003919750281135_120901269.0DomainKH 14
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028158_22901269.0DomainKH 1
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028230_30201269.0DomainKH 2
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028303_37101269.0DomainKH 3
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028372_44201269.0DomainKH 4
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028443_51401269.0DomainKH 5
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028515_58801269.0DomainKH 6
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028589_66001269.0DomainKH 7
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028661_73401269.0DomainKH 8
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028735_80701269.0DomainKH 9
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028808_88001269.0DomainKH 10
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028881_97901269.0DomainKH 11
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391975028980_105901269.0DomainKH 12
TgeneHDLBPchr19:35758865chr2:242202277ENST000003919760281060_113401269.0DomainKH 13
TgeneHDLBPchr19:35758865chr2:242202277ENST000003919760281135_120901269.0DomainKH 14
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028158_22901269.0DomainKH 1
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028230_30201269.0DomainKH 2
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028303_37101269.0DomainKH 3
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028372_44201269.0DomainKH 4
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028443_51401269.0DomainKH 5
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028515_58801269.0DomainKH 6
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028589_66001269.0DomainKH 7
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028661_73401269.0DomainKH 8
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028735_80701269.0DomainKH 9
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028808_88001269.0DomainKH 10
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028881_97901269.0DomainKH 11
TgeneHDLBPchr19:35758865chr2:242202277ENST00000391976028980_105901269.0DomainKH 12
TgeneHDLBPchr19:35758865chr2:242202277ENST000004271830281060_113401236.0DomainKH 13
TgeneHDLBPchr19:35758865chr2:242202277ENST000004271830281135_120901236.0DomainKH 14
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028158_22901236.0DomainKH 1
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028230_30201236.0DomainKH 2
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028303_37101236.0DomainKH 3
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028372_44201236.0DomainKH 4
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028443_51401236.0DomainKH 5
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028515_58801236.0DomainKH 6
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028589_66001236.0DomainKH 7
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028661_73401236.0DomainKH 8
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028735_80701236.0DomainKH 9
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028808_88001236.0DomainKH 10
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028881_97901236.0DomainKH 11
TgeneHDLBPchr19:35758865chr2:242202277ENST00000427183028980_105901236.0DomainKH 12

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for LSR-HDLBP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>50240_50240_1_LSR-HDLBP_LSR_chr19_35758865_ENST00000354900_HDLBP_chr2_242202277_ENST00000310931_length(transcript)=6003nt_BP=2105nt
CGGGTGGAGTGTGGCTCGGAGGACCGCGGCGGGTCAAGCACCTTTCTCCCCCATATCTGAAAGCATGCCCTTTGTCCACGTCGTTTACGC
TCATTAAAACTTCCAGAATGCAACAGGACGGACTTGGAGTAGGGACAAGGAACGGAAGTGGGAAGGGGAGGAGCGTGCACCCCTCCTGGC
CTTGGTGCGCGCCGCGCCCCCTAAGGTACTTTGGAAGGGACGCGCGGGCCAGACGCGCCCAGACGGCCGCGATGGCGCTGTTGGCCGGCG
GGCTCTCCAGAGGGCTGGGCTCCCACCCGGCCGCCGCAGGCCGGGACGCGGTCGTCTTCGTGTGGCTTCTGCTTAGCACCTGGTGCACAG
CTCCTGCCAGGGCCATCCAGGTGACCGTGTCCAACCCCTACCACGTGGTGATCCTCTTCCAGCCTGTGACCCTGCCCTGTACCTACCAGA
TGACCTCGACCCCCACGCAACCCATCGTCATCTGGAAGTACAAGTCTTTCTGCCGGGACCGCATCGCCGATGCCTTCTCCCCGGCCAGCG
TCGACAACCAGCTCAATGCCCAGCTGGCAGCCGGGAACCCAGGCTACAACCCCTACGTTGAGTGCCAGGACAGCGTGCGCACCGTCAGGG
TCGTGGCCACCAAGCAGGGCAACGCTGTGACCCTGGGAGATTACTACCAGGGCCGGAGGATTACCATCACCGGAAATGCTGACCTGACCT
TTGACCAGACGGCGTGGGGGGACAGTGGTGTGTATTACTGCTCCGTGGTCTCAGCCCAGGACCTCCAGGGGAACAATGAGGCCTACGCAG
AGCTCATCGTCCTTGACTGGCTCTTCGTGGTTGTGGTATGCCTGGCTGCCTTCCTCATCTTCCTCCTCCTGGGCATCTGCTGGTGCCAGT
GCTGCCCGCACACTTGCTGCTGCTACGTCAGGTGCCCCTGCTGCCCAGACAAGTGCTGCTGCCCCGAGGCCCTGTATGCCGCCGGCAAAG
CAGCCACCTCAGGTGTTCCCAGCATTTATGCCCCCAGCACCTATGCCCACCTGTCTCCCGCCAAGACCCCACCCCCACCAGCTATGATTC
CCATGGGCCCTGCCTACAACGGGTACCCTGGAGGATACCCTGGAGACGTTGACAGGAGTAGCTCAGCTGGTGGCCAAGGCTCCTATGTAC
CCCTGCTTCGGGACACGGACAGCAGTGTGGCCTCTGAAGTCCGCAGTGGCTACAGGATTCAGGCCAGCCAGCAGGACGACTCCATGCGGG
TCCTGTACTACATGGAGAAGGAGCTGGCCAACTTCGACCCTTCTCGACCTGGCCCCCCCAGTGGCCGTGTGGAGCGGGCCATGAGTGAAG
TCACCTCCCTCCACGAGGACGACTGGCGATCTCGGCCTTCCCGGGGCCCTGCCCTCACCCCGATCCGGGATGAGGAGTGGGGTGGCCACT
CCCCCCGGAGTCCCAGGGGATGGGACCAGGAGCCCGCCAGGGAGCAGGCAGGCGGGGGCTGGCGGGCCAGGCGGCCCCGGGCCCGCTCCG
TGGACGCCCTGGACGACCTCACCCCGCCGAGCACCGCCGAGTCAGGGAGCAGGTCTCCCACGAGTAATGGTGGGAGAAGCCGGGCCTACA
TGCCCCCGCGGAGCCGCAGCCGGGACGACCTCTATGACCAAGACGACTCGAGGGACTTCCCACGCTCCCGGGACCCCCACTACGACGACT
TCAGGTCTCGGGAGCGCCCTCCTGCCGACCCCAGGTCCCACCACCACCGTACCCGGGACCCTCGGGACAACGGCTCCAGGTCCGGGGACC
TCCCCTATGATGGGCGGCTACTGGAGGAGGCTGTGAGGAAGAAGGGGTCGGAGGAGAGGAGGAGACCCCACAAGGAGGAGGAGGAAGAGG
CCTACTACCCGCCCGCGCCGCCCCCGTACTCGGAGACCGACTCGCAGGCGTCCCGAGAGCGCAGGCTCAAGAAGAACTTGGCCCTGAGTC
GGGAAAGTTTAGTCGTCTGATCTGACGTTTTCTACGTAGCTTTTGTATTTTTTTTTTTAATTTGAAGGAACACTGATGAAGCCCTGCCAT
ACCCCTCCCGAGTCTAATAAAACGTATAATCACAAGCTCCTGACATGAGCAGCTCTGAGGAATTTCCCAGCTTTGGGGCTCAGGTGGCTC
CCAAGACCCTCCCTTGGGGCCCCAAACGATAATGATCAAAAAGAACAGAACCCTCTCCAGCCTGCTGACCCAAACCCAACCACACAATGG
TTTGTCTCAATCTGACCCAGCGGCTGGACCCTCCGTAAATTGTTGACGCTCTTCCCCCTTCCCGAGGTCCCGCAGGGAGCCTAGCGCCTG
GCTGTGTGTGCGGCCGCTCCTCCAGGCCTGGCCGTGCCCGCTCAGGACCTGCTCCACTGTTTAACACTAAACCAAGGTCATGAGCATTCG
TGCTAAGATAACAGACTCCAGCTCCTGGTCCACCCGGCATGTCAGTCAGCACTCTGGCCTTCATCACGAGAGCTCCGCAGCCGTGGCTAG
GATTCCACTTCCTGTGTCATGACCTCAGGAAATAAACGTCCTTGACTTTATAAAAGCCAAACTAGCTGACGTGGTGGACAGTGAGGCGCT
GCAGGTATACATGAAACCCCCAGCACACGAAGAGGCCAAGGCACCTTCCAGAGGCTTTGTGGTGCGGGACGCACCCTGGACCGCCAGCAG
CAGTGAGAAGGTGGACATTCGCTTCCCACAGAGCGGAGCCCCAGACCCCAACTGCGTCACTGTGACGGGGCTCCCAGAGAATGTGGAGGA
AGCCATCGACCACATCCTCAATCTGGAGGAGGAATACCCCCAGGACCAAATTACCATCACAGGGTACGAAAAGAACACAGAAGCTGCCAG
GGATGCTATACTGAGAATTGTGGGTGAACTTGAGCAGATGGTTTCTGAGGACGTCCCGCTGGACCACCGCGTTCACGCCCGCATCATTGG
TGCCCGCGGCAAAGCCATTCGCAAAATCATGGACGAATTCAAGGCTTTAAGGAGTTTTAAGCTGAGTGTCACTGTAGACCCCAAATACCA
TCCCAAGATTATCGGGAGAAAGGGGGCAGTAATTACCCAAATCCGGTTGGAGCATGACGTGAACATCCAGTTTCCTGATAAGGACGATGG
GAACCAGGTGAACATACATGTCCCGGCACCTGAGCTGCAGTCTGACATCATCGCCATCACGGGCCTCGCTGCAAATTTGGACCGGGCCAA
GGCTGGACTGCTGGAGCGTGTGAAGGAGCTACAGGCCGAGCAGGAGGACCGGGCATTGGTTCCTGTCACCATTGAAGTAGAGGTGCCCTT
TGACCTTCACCGTTACGTTATTGGGCAGAAAGGAAGTGGGATCCGCAAGATGATGGATGAGTTTGAGTTCACAGTACAGAGCCAGTTGTC
CAGGAGAATGGGGACGAAGCTGGGGAGGGGAGAGAGGCTAAAGATTGTGACCCCGGCTCTCCAAGGAGGTGTGACATCATCATCATCTCT
GGCCGGAAAGAAAAGTGTGAGGCTGCCAAGGAAGCTCTGGAGGAAGCTCAGGTGACATTAGAATGTGCTATACCCCAGAAATTCCATCGA
TCTGTCATGGGCCCCAAAGGTTCCAGAATCCAGCAGATTACTCGGGATTTCAGTGTTCAAATTAAATTCCCAGACAGAGAGGAGAACGCA
GGATAATGTGGTGGAAGACTCCATGCTGGTGGACCCCAAGCACCACCGCCACTTCGTCATCCGCAGAGGCCAGGTCTTGCGGGAGATTGC
TGAAGAGTATGGCGGGGTGATGGTCAGCTTCCCACGCTCTGGCACACAGAGCGACAAAGTCACCCTCAAGGGCGCCAAGGACTGTGTGGA
GGCAGCCAAGAAACGCATTCAGGAGATCATTGAGGACCTGCAAACCAAGAGTTTCACTGTTGACATCCGCGCCAAGCCAGAATACCACAA
ATTCCTCATCGGCAAGGGGGGCGGCAAAATTCGCAAGGTGCGCGACAGCACTGGAGCACGTGTCATCTTCCCTGCGGCTGAGGACAAGGA
CCAGGACCTGATCACCATCATTGGAAAGGAGGACGCCGTCCGAGAGGCACAGAAGGAGCTGGAGGCCTTGATCCAAAACCTGGCCAACAT
AGCCGAGGTAGAGGTCTCCATCCCTGCCAAGCTGCACAACTCCCTCATTGGCACCAAGGGCCGTCTGATCCGCTCCATCATGGAGGAGTG
CGGCGGGGTCCACATTCACTTTCCCGTGGAAGGTTCAGGAAGCGACACCGTTGTTATCAGGGGCCCTTCCTCGGATGTGGAGAAGGCCAA
GAAGCAGCTCCTGCATCTGGCGGAGGAGAAGATTCGTGAAGAAAGCAACACCAAAATCGACCTTCCAGCAGAGAATAGCAATTCAGAGAC
CATTATCATCACAGGCAAGCGAGCCAACTGCGAAGCTGCCCGGAGCAGGATTCTGTCTATTCAGAAAGACCTGGTGGAAAATAGCTATTC
AATTTCTGTTCCGATCTTCAAACAGTTTCACAAGAATATCATTGGGAAAGGAGGCGCAAACATTAAAAAGGTCATCATTAACTTTCCAGA
CCCAGCACAAAAAAGTGACATTGTCCAGCTCAGAGGACCTAAGAATGAGGTGGAAAAATGCACAAAATACATGCAGAAGATGGTGGCAGA
TCTGGAAAATGAGCGTACCAAGGATCTAATCATTGAGCAAAGATTTCATCGCACAATCATTGGGCAGAAGGGTGAACGGATCCGTGAAAT
TCGTGACAAATTCCCAGAGTAAACAGAATCAAAGACCAGTACAAGGTGTCCGTGCGCATCCCTCCTGACAGTGAGAAGAGCAATTTGATC
CGCATCGAGGGGGACCCACAGGGCGTGCAGCAGGCCAAGCGAGAGCTGCTGGAGCTTGCATCTCGCATGATTAACCGGATGGACTATGTG
GAGATCAACATCGACCACAAGTTCCACAGGCACCTCATTGGGAAGAGCGGTGCCAACAGTTCACATCGAGTTCACAGAGGGCGAAGACAA
GATCACCCTGGAGGGCCCTACAGAGGATGTCAATGTGGCCCAGGAACAGATAGAAGGCATGGTCAAAGATTTGGCCAATAGCTTCACCGT
CTCCTCTGTCGCCGCCCCTTCCTGGCTTCACCGTTTCATCATTGGCAAGAAAGGGCAGAACCTGGCCAAAATCACTCAGCAGATGCCAAA
GAAAAAGAAGACTACAACCATTGCAGTGGAAGTGAAGAAATCCCAACACAAGTATGTCATTGGGCCCAAGGGCAATTCATTGCAGGAGAT
CCTTGAGAGAACTGGAGTTTCCGTTGAGATCCCACCCTCAGACAGCATCTCTGAGACTGTAATACTTCGAGGCGAACCTGAAAAGTTAGG
TCAGGCGTTGACTGAAGTCTATGCCAAGGACAAACGTGCTGTGGAGAGGCTAGAAGTAGAAAAGGCATTCCACCCCTTCATCGCTGGGCC
GTATAATAGACTGGTTGGCGAGATCATGCAGGAGACAGGCACGCGCATCAACATCCCCCCACCCAGCGTGAACCGGACAGAGATTGTCTT
CACTGGAGAGAAGGAACAGTTGGCTCAGGCTGTGGCTCGCATCAAGAAGATTTATGAGGAGAAGGCCTCAGCAACTGTTGCCATTCCCAA
AGAACACCATCGCTTTGTTATTGGCAAAAATGGAGAGAAACTGCAAGACTTGGAGCTAAAAACTGCAACCAAAATCCAGATCCCACGCCC
AGATGACCCCAGCAATCAGATCAAGATCACTGGCACCAAAGAGGGCATCGAGAAAGCTCGCCATGAAGTCTTACTCATCTCTGCCGAGCA
GAAGCAAAAATCTGCCTTGAGATCATGCAGAGAACTGGTGCTCACTTGGAGCTGTCTTTGGCCAAAGACCAAGGCCTCTCCATCATGGTG

>50240_50240_1_LSR-HDLBP_LSR_chr19_35758865_ENST00000354900_HDLBP_chr2_242202277_ENST00000310931_length(amino acids)=647AA_BP=
MKACPLSTSFTLIKTSRMQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGLGSHPAAAGRDAVV
FVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPY
VECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLDWLFVVVVCLAAFL
IFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDR
SSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPAL
TPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRD
FPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASR

--------------------------------------------------------------
>50240_50240_2_LSR-HDLBP_LSR_chr19_35758865_ENST00000354900_HDLBP_chr2_242202277_ENST00000391975_length(transcript)=7951nt_BP=2105nt
CGGGTGGAGTGTGGCTCGGAGGACCGCGGCGGGTCAAGCACCTTTCTCCCCCATATCTGAAAGCATGCCCTTTGTCCACGTCGTTTACGC
TCATTAAAACTTCCAGAATGCAACAGGACGGACTTGGAGTAGGGACAAGGAACGGAAGTGGGAAGGGGAGGAGCGTGCACCCCTCCTGGC
CTTGGTGCGCGCCGCGCCCCCTAAGGTACTTTGGAAGGGACGCGCGGGCCAGACGCGCCCAGACGGCCGCGATGGCGCTGTTGGCCGGCG
GGCTCTCCAGAGGGCTGGGCTCCCACCCGGCCGCCGCAGGCCGGGACGCGGTCGTCTTCGTGTGGCTTCTGCTTAGCACCTGGTGCACAG
CTCCTGCCAGGGCCATCCAGGTGACCGTGTCCAACCCCTACCACGTGGTGATCCTCTTCCAGCCTGTGACCCTGCCCTGTACCTACCAGA
TGACCTCGACCCCCACGCAACCCATCGTCATCTGGAAGTACAAGTCTTTCTGCCGGGACCGCATCGCCGATGCCTTCTCCCCGGCCAGCG
TCGACAACCAGCTCAATGCCCAGCTGGCAGCCGGGAACCCAGGCTACAACCCCTACGTTGAGTGCCAGGACAGCGTGCGCACCGTCAGGG
TCGTGGCCACCAAGCAGGGCAACGCTGTGACCCTGGGAGATTACTACCAGGGCCGGAGGATTACCATCACCGGAAATGCTGACCTGACCT
TTGACCAGACGGCGTGGGGGGACAGTGGTGTGTATTACTGCTCCGTGGTCTCAGCCCAGGACCTCCAGGGGAACAATGAGGCCTACGCAG
AGCTCATCGTCCTTGACTGGCTCTTCGTGGTTGTGGTATGCCTGGCTGCCTTCCTCATCTTCCTCCTCCTGGGCATCTGCTGGTGCCAGT
GCTGCCCGCACACTTGCTGCTGCTACGTCAGGTGCCCCTGCTGCCCAGACAAGTGCTGCTGCCCCGAGGCCCTGTATGCCGCCGGCAAAG
CAGCCACCTCAGGTGTTCCCAGCATTTATGCCCCCAGCACCTATGCCCACCTGTCTCCCGCCAAGACCCCACCCCCACCAGCTATGATTC
CCATGGGCCCTGCCTACAACGGGTACCCTGGAGGATACCCTGGAGACGTTGACAGGAGTAGCTCAGCTGGTGGCCAAGGCTCCTATGTAC
CCCTGCTTCGGGACACGGACAGCAGTGTGGCCTCTGAAGTCCGCAGTGGCTACAGGATTCAGGCCAGCCAGCAGGACGACTCCATGCGGG
TCCTGTACTACATGGAGAAGGAGCTGGCCAACTTCGACCCTTCTCGACCTGGCCCCCCCAGTGGCCGTGTGGAGCGGGCCATGAGTGAAG
TCACCTCCCTCCACGAGGACGACTGGCGATCTCGGCCTTCCCGGGGCCCTGCCCTCACCCCGATCCGGGATGAGGAGTGGGGTGGCCACT
CCCCCCGGAGTCCCAGGGGATGGGACCAGGAGCCCGCCAGGGAGCAGGCAGGCGGGGGCTGGCGGGCCAGGCGGCCCCGGGCCCGCTCCG
TGGACGCCCTGGACGACCTCACCCCGCCGAGCACCGCCGAGTCAGGGAGCAGGTCTCCCACGAGTAATGGTGGGAGAAGCCGGGCCTACA
TGCCCCCGCGGAGCCGCAGCCGGGACGACCTCTATGACCAAGACGACTCGAGGGACTTCCCACGCTCCCGGGACCCCCACTACGACGACT
TCAGGTCTCGGGAGCGCCCTCCTGCCGACCCCAGGTCCCACCACCACCGTACCCGGGACCCTCGGGACAACGGCTCCAGGTCCGGGGACC
TCCCCTATGATGGGCGGCTACTGGAGGAGGCTGTGAGGAAGAAGGGGTCGGAGGAGAGGAGGAGACCCCACAAGGAGGAGGAGGAAGAGG
CCTACTACCCGCCCGCGCCGCCCCCGTACTCGGAGACCGACTCGCAGGCGTCCCGAGAGCGCAGGCTCAAGAAGAACTTGGCCCTGAGTC
GGGAAAGTTTAGTCGTCTGATCTGACGTTTTCTACGTAGCTTTTGTATTTTTTTTTTTAATTTGAAGGAACACTGATGAAGCCCTGCCAT
ACCCCTCCCGAGTCTAATAAAACGTATAATCACAAGCTCCTGACATGAGCAGCTCTGAGGAATTTCCCAGCTTTGGGGCTCAGGTGGCTC
CCAAGACCCTCCCTTGGGGCCCCAAACGATAATGATCAAAAAGAACAGAACCCTCTCCAGCCTGCTGACCCAAACCCAACCACACAATGG
TTTGTCTCAATCTGACCCAGCGGCTGGACCCTCCGTAAATTGTTGACGCTCTTCCCCCTTCCCGAGGTCCCGCAGGGAGCCTAGCGCCTG
GCTGTGTGTGCGGCCGCTCCTCCAGGCCTGGCCGTGCCCGCTCAGGACCTGCTCCACTGTTTAACACTAAACCAAGGTCATGAGCATTCG
TGCTAAGATAACAGACTCCAGCTCCTGGTCCACCCGGCATGTCAGTCAGCACTCTGGCCTTCATCACGAGAGCTCCGCAGCCGTGGCTAG
GATTCCACTTCCTGTGTCATGACCTCAGGAAATAAACGTCCTTGACTTTATAAAAGCCAAACGTTTGCCCTCTTCCTTTCCCACCTCCCT
CCTGCCAGTTTCCCTTGGTCCAGACAGTCCTGTTTGTGGAGTGCAATCAGCCTCCTCCAGCTGCCAGAGCGCCTCAGCACAGGTGTCAGG
GTGCAAGGAAGACCTGGCAATGGACAGCAGGAGGCAGGTTCCTGGAGCTGGGGGGTGACCTGAGAGGCAGAGGGTGACGGGTTCTCAGGC
AGTCCTGATTTTACCTGCCGTGGGGTCTGAAAGCACCAAGGGTCCCTGCCCCTACCTCCACTGCCAGACCCTCAGCCTGAGGTCTGGTGA
GTGGAGCCTGGAGGCAAGGTGGTAGGCACCATCTGGGTCCCCTGTGGCCGTCACAGTGTCTGCTGTGATTGAGATGCGCACAGGTTGGGG
GAGGTAGGGCCTTACGCTTGTCCTCAGTGGGGGCAGTTTGCCTTAGATGACAGCTGGGCTCTTCTTCACACCACCTGCAGCCCCTCCCTG
CCCCTGCCCTAGCTGCTGTGTGTTCAGTTGCCTTCTTTCTACCTCAGCCGGCGTGGAGTGGTCTCTGTGCAGTTAGTGCCACCCCACACA
CCCGTCTCTTGATTGAGATGTTTCTGGTGGTTATGGGTTTCCCGTGGAGCTGGGGGTGGGCGCCGTGTACCTAAGCTGGAGGCTGGCGCT
CTCCCTCAGCACAGGTGGGTCAGTGGCCAGCAGGCCCATCTGGAGTGGGAGTGGGCACTTCCACCCCGCCCACAGGCCATCCGGCTGTGC
AGGCCAGCCCCTAGGAGCAGGTCCCGGGTGACTGGCAGTTTTCACGGTCTAGGGCCGAGACGATGGCATGGGGCCTAGAGCATGAGGTAG
AGCAGAATGCAGACCACGCCGCTGGATGCCGAGAGACCCTGCTCTCCGAGGGAGGCATCTGTGTCATGCTGTGAGGGCTGAGGACGGGGC
CCTAGTCTCTGGTTTTCTGGTCTTAACATCCTTATCTGTGTCCGCCACGGAGGTGACTGAGCTGCTAGCGAGTTGTCCTGTCCCAGGTAC
TTGAGTTTTGGAAAAGCTGACTCACGCCCATCCATCTCACAGCCCTTCCCTGGGGACAGTCGCTTCCGCCTTGACACCTCACTCTCAGTT
GAATAACTCAAGCTTGGTCATCTTCAGACTCGAATTCTTGAGTAGACCCAGACGGCTTAGCCCAAGTCTAGTTGCAGCTGCCTCGGCAAG
TCCCCATTTGCTCAGGCAGCCCTGAATGGGCCTGTTTACAGGAATGGTAAATTGGGATTGGAAGGAATATAGCTTCCAGCTTCATAGGCT
AGGGTGACCACGGCTTAGGAAACAGGGAAAGAAAGCAAGGCCCTTTTCCTGCCTTTCCCGGGATCTGTCTACTCCACCTCCACGGGGGAG
GCCAGTGGGGAAGGGCTGTCACCTCTTCCCCATCTGCATGAGTTCTGGAACTCTGTCCTGTTGGCTGCTTGCTTCCAGCTCCCCCCAATC
TCCATCGCAGCGGGTTCCTCCTGTCTTTTCTACAGTGTCATAAAACATCCTGCCCCTACCCTCTCCCAAAGGTCAATTTTAATTCTCACC
AAGTTTTGCACATCTCTGTATGTCGCTTGATGTCTTAGACGCGAGCCCTTTCCTAAACTGTTCAGCGCTCTCTTTTCCTTTGGGTGGTTG
TTGCAAGGGTGATGACATGACTGTCCCCAGGCCTGTCTCCCTGAAGCGTCTGTGCTGTCAGGACAGCCCTGGGCAGAGATGAGGCAGGGG
TGAGGCGTGCGTGTGCTTTTCCTCCTTGTTGGATGTCTTCCATATCATCTGTTTCCATAGCTACAATCCATCCCTTGGCCTTAACTTTGG
AATTTGGAGATTATATGCAAACATGTGTAAAGGCTCATGAATATGGATGACACTGGAATTTTATAAATTCTAAAATAAAACCCGAAACCA
GATGTAGCATGCTGGGACTCATTTTGTCACTAGCTGACGTGGTGGACAGTGAGGCGCTGCAGGTATACATGAAACCCCCAGCACACGAAG
AGGCCAAGGCACCTTCCAGAGGCTTTGTGGTGCGGGACGCACCCTGGACCGCCAGCAGCAGTGAGAAGGTGGACATTCGCTTCCCACAGA
GCGGAGCCCCAGACCCCAACTGCGTCACTGTGACGGGGCTCCCAGAGAATGTGGAGGAAGCCATCGACCACATCCTCAATCTGGAGGAGG
AATACCCCCAGGACCAAATTACCATCACAGGGTACGAAAAGAACACAGAAGCTGCCAGGGATGCTATACTGAGAATTGTGGGTGAACTTG
AGCAGATGGTTTCTGAGGACGTCCCGCTGGACCACCGCGTTCACGCCCGCATCATTGGTGCCCGCGGCAAAGCCATTCGCAAAATCATGG
ACGAATTCAAGGCTTTAAGGAGTTTTAAGCTGAGTGTCACTGTAGACCCCAAATACCATCCCAAGATTATCGGGAGAAAGGGGGCAGTAA
TTACCCAAATCCGGTTGGAGCATGACGTGAACATCCAGTTTCCTGATAAGGACGATGGGAACCAGGTGAACATACATGTCCCGGCACCTG
AGCTGCAGTCTGACATCATCGCCATCACGGGCCTCGCTGCAAATTTGGACCGGGCCAAGGCTGGACTGCTGGAGCGTGTGAAGGAGCTAC
AGGCCGAGCAGGAGGACCGGGCATTGGTTCCTGTCACCATTGAAGTAGAGGTGCCCTTTGACCTTCACCGTTACGTTATTGGGCAGAAAG
GAAGTGGGATCCGCAAGATGATGGATGAGTTTGAGTTCACAGTACAGAGCCAGTTGTCCAGGAGAATGGGGACGAAGCTGGGGAGGGGAG
AGAGGCTAAAGATTGTGACCCCGGCTCTCCAAGGAGGTGTGACATCATCATCATCTCTGGCCGGAAAGAAAAGTGTGAGGCTGCCAAGGA
AGCTCTGGAGGAAGCTCAGGTGACATTAGAATGTGCTATACCCCAGAAATTCCATCGATCTGTCATGGGCCCCAAAGGTTCCAGAATCCA
GCAGATTACTCGGGATTTCAGTGTTCAAATTAAATTCCCAGACAGAGAGGAGAACGCAGGATAATGTGGTGGAAGACTCCATGCTGGTGG
ACCCCAAGCACCACCGCCACTTCGTCATCCGCAGAGGCCAGGTCTTGCGGGAGATTGCTGAAGAGTATGGCGGGGTGATGGTCAGCTTCC
CACGCTCTGGCACACAGAGCGACAAAGTCACCCTCAAGGGCGCCAAGGACTGTGTGGAGGCAGCCAAGAAACGCATTCAGGAGATCATTG
AGGACCTGCAAACCAAGAGTTTCACTGTTGACATCCGCGCCAAGCCAGAATACCACAAATTCCTCATCGGCAAGGGGGGCGGCAAAATTC
GCAAGGTGCGCGACAGCACTGGAGCACGTGTCATCTTCCCTGCGGCTGAGGACAAGGACCAGGACCTGATCACCATCATTGGAAAGGAGG
ACGCCGTCCGAGAGGCACAGAAGGAGCTGGAGGCCTTGATCCAAAACCTGGCCAACATAGCCGAGGTAGAGGTCTCCATCCCTGCCAAGC
TGCACAACTCCCTCATTGGCACCAAGGGCCGTCTGATCCGCTCCATCATGGAGGAGTGCGGCGGGGTCCACATTCACTTTCCCGTGGAAG
GTTCAGGAAGCGACACCGTTGTTATCAGGGGCCCTTCCTCGGATGTGGAGAAGGCCAAGAAGCAGCTCCTGCATCTGGCGGAGGAGAAGA
TTCGTGAAGAAAGCAACACCAAAATCGACCTTCCAGCAGAGAATAGCAATTCAGAGACCATTATCATCACAGGCAAGCGAGCCAACTGCG
AAGCTGCCCGGAGCAGGATTCTGTCTATTCAGAAAGACCTGGTGGAAAATAGCTATTCAATTTCTGTTCCGATCTTCAAACAGTTTCACA
AGAATATCATTGGGAAAGGAGGCGCAAACATTAAAAAGGTCATCATTAACTTTCCAGACCCAGCACAAAAAAGTGACATTGTCCAGCTCA
GAGGACCTAAGAATGAGGTGGAAAAATGCACAAAATACATGCAGAAGATGGTGGCAGATCTGGAAAATGAGCGTACCAAGGATCTAATCA
TTGAGCAAAGATTTCATCGCACAATCATTGGGCAGAAGGGTGAACGGATCCGTGAAATTCGTGACAAATTCCCAGAGTAAACAGAATCAA
AGACCAGTACAAGGTGTCCGTGCGCATCCCTCCTGACAGTGAGAAGAGCAATTTGATCCGCATCGAGGGGGACCCACAGGGCGTGCAGCA
GGCCAAGCGAGAGCTGCTGGAGCTTGCATCTCGCATGATTAACCGGATGGACTATGTGGAGATCAACATCGACCACAAGTTCCACAGGCA
CCTCATTGGGAAGAGCGGTGCCAACAGTTCACATCGAGTTCACAGAGGGCGAAGACAAGATCACCCTGGAGGGCCCTACAGAGGATGTCA
ATGTGGCCCAGGAACAGATAGAAGGCATGGTCAAAGATTTGGCCAATAGCTTCACCGTCTCCTCTGTCGCCGCCCCTTCCTGGCTTCACC
GTTTCATCATTGGCAAGAAAGGGCAGAACCTGGCCAAAATCACTCAGCAGATGCCAAAGAAAAAGAAGACTACAACCATTGCAGTGGAAG
TGAAGAAATCCCAACACAAGTATGTCATTGGGCCCAAGGGCAATTCATTGCAGGAGATCCTTGAGAGAACTGGAGTTTCCGTTGAGATCC
CACCCTCAGACAGCATCTCTGAGACTGTAATACTTCGAGGCGAACCTGAAAAGTTAGGTCAGGCGTTGACTGAAGTCTATGCCAAGGACA
AACGTGCTGTGGAGAGGCTAGAAGTAGAAAAGGCATTCCACCCCTTCATCGCTGGGCCGTATAATAGACTGGTTGGCGAGATCATGCAGG
AGACAGGCACGCGCATCAACATCCCCCCACCCAGCGTGAACCGGACAGAGATTGTCTTCACTGGAGAGAAGGAACAGTTGGCTCAGGCTG
TGGCTCGCATCAAGAAGATTTATGAGGAGAAGGCCTCAGCAACTGTTGCCATTCCCAAAGAACACCATCGCTTTGTTATTGGCAAAAATG
GAGAGAAACTGCAAGACTTGGAGCTAAAAACTGCAACCAAAATCCAGATCCCACGCCCAGATGACCCCAGCAATCAGATCAAGATCACTG
GCACCAAAGAGGGCATCGAGAAAGCTCGCCATGAAGTCTTACTCATCTCTGCCGAGCAGAAGCAAAAATCTGCCTTGAGATCATGCAGAG
AACTGGTGCTCACTTGGAGCTGTCTTTGGCCAAAGACCAAGGCCTCTCCATCATGGTGTCAGGAAAGCTGGATGCTGTCATGAAAGCTCG

>50240_50240_2_LSR-HDLBP_LSR_chr19_35758865_ENST00000354900_HDLBP_chr2_242202277_ENST00000391975_length(amino acids)=647AA_BP=
MKACPLSTSFTLIKTSRMQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGLGSHPAAAGRDAVV
FVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPY
VECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLDWLFVVVVCLAAFL
IFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDR
SSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPAL
TPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRD
FPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASR

--------------------------------------------------------------
>50240_50240_3_LSR-HDLBP_LSR_chr19_35758865_ENST00000354900_HDLBP_chr2_242202277_ENST00000391976_length(transcript)=6003nt_BP=2105nt
CGGGTGGAGTGTGGCTCGGAGGACCGCGGCGGGTCAAGCACCTTTCTCCCCCATATCTGAAAGCATGCCCTTTGTCCACGTCGTTTACGC
TCATTAAAACTTCCAGAATGCAACAGGACGGACTTGGAGTAGGGACAAGGAACGGAAGTGGGAAGGGGAGGAGCGTGCACCCCTCCTGGC
CTTGGTGCGCGCCGCGCCCCCTAAGGTACTTTGGAAGGGACGCGCGGGCCAGACGCGCCCAGACGGCCGCGATGGCGCTGTTGGCCGGCG
GGCTCTCCAGAGGGCTGGGCTCCCACCCGGCCGCCGCAGGCCGGGACGCGGTCGTCTTCGTGTGGCTTCTGCTTAGCACCTGGTGCACAG
CTCCTGCCAGGGCCATCCAGGTGACCGTGTCCAACCCCTACCACGTGGTGATCCTCTTCCAGCCTGTGACCCTGCCCTGTACCTACCAGA
TGACCTCGACCCCCACGCAACCCATCGTCATCTGGAAGTACAAGTCTTTCTGCCGGGACCGCATCGCCGATGCCTTCTCCCCGGCCAGCG
TCGACAACCAGCTCAATGCCCAGCTGGCAGCCGGGAACCCAGGCTACAACCCCTACGTTGAGTGCCAGGACAGCGTGCGCACCGTCAGGG
TCGTGGCCACCAAGCAGGGCAACGCTGTGACCCTGGGAGATTACTACCAGGGCCGGAGGATTACCATCACCGGAAATGCTGACCTGACCT
TTGACCAGACGGCGTGGGGGGACAGTGGTGTGTATTACTGCTCCGTGGTCTCAGCCCAGGACCTCCAGGGGAACAATGAGGCCTACGCAG
AGCTCATCGTCCTTGACTGGCTCTTCGTGGTTGTGGTATGCCTGGCTGCCTTCCTCATCTTCCTCCTCCTGGGCATCTGCTGGTGCCAGT
GCTGCCCGCACACTTGCTGCTGCTACGTCAGGTGCCCCTGCTGCCCAGACAAGTGCTGCTGCCCCGAGGCCCTGTATGCCGCCGGCAAAG
CAGCCACCTCAGGTGTTCCCAGCATTTATGCCCCCAGCACCTATGCCCACCTGTCTCCCGCCAAGACCCCACCCCCACCAGCTATGATTC
CCATGGGCCCTGCCTACAACGGGTACCCTGGAGGATACCCTGGAGACGTTGACAGGAGTAGCTCAGCTGGTGGCCAAGGCTCCTATGTAC
CCCTGCTTCGGGACACGGACAGCAGTGTGGCCTCTGAAGTCCGCAGTGGCTACAGGATTCAGGCCAGCCAGCAGGACGACTCCATGCGGG
TCCTGTACTACATGGAGAAGGAGCTGGCCAACTTCGACCCTTCTCGACCTGGCCCCCCCAGTGGCCGTGTGGAGCGGGCCATGAGTGAAG
TCACCTCCCTCCACGAGGACGACTGGCGATCTCGGCCTTCCCGGGGCCCTGCCCTCACCCCGATCCGGGATGAGGAGTGGGGTGGCCACT
CCCCCCGGAGTCCCAGGGGATGGGACCAGGAGCCCGCCAGGGAGCAGGCAGGCGGGGGCTGGCGGGCCAGGCGGCCCCGGGCCCGCTCCG
TGGACGCCCTGGACGACCTCACCCCGCCGAGCACCGCCGAGTCAGGGAGCAGGTCTCCCACGAGTAATGGTGGGAGAAGCCGGGCCTACA
TGCCCCCGCGGAGCCGCAGCCGGGACGACCTCTATGACCAAGACGACTCGAGGGACTTCCCACGCTCCCGGGACCCCCACTACGACGACT
TCAGGTCTCGGGAGCGCCCTCCTGCCGACCCCAGGTCCCACCACCACCGTACCCGGGACCCTCGGGACAACGGCTCCAGGTCCGGGGACC
TCCCCTATGATGGGCGGCTACTGGAGGAGGCTGTGAGGAAGAAGGGGTCGGAGGAGAGGAGGAGACCCCACAAGGAGGAGGAGGAAGAGG
CCTACTACCCGCCCGCGCCGCCCCCGTACTCGGAGACCGACTCGCAGGCGTCCCGAGAGCGCAGGCTCAAGAAGAACTTGGCCCTGAGTC
GGGAAAGTTTAGTCGTCTGATCTGACGTTTTCTACGTAGCTTTTGTATTTTTTTTTTTAATTTGAAGGAACACTGATGAAGCCCTGCCAT
ACCCCTCCCGAGTCTAATAAAACGTATAATCACAAGCTCCTGACATGAGCAGCTCTGAGGAATTTCCCAGCTTTGGGGCTCAGGTGGCTC
CCAAGACCCTCCCTTGGGGCCCCAAACGATAATGATCAAAAAGAACAGAACCCTCTCCAGCCTGCTGACCCAAACCCAACCACACAATGG
TTTGTCTCAATCTGACCCAGCGGCTGGACCCTCCGTAAATTGTTGACGCTCTTCCCCCTTCCCGAGGTCCCGCAGGGAGCCTAGCGCCTG
GCTGTGTGTGCGGCCGCTCCTCCAGGCCTGGCCGTGCCCGCTCAGGACCTGCTCCACTGTTTAACACTAAACCAAGGTCATGAGCATTCG
TGCTAAGATAACAGACTCCAGCTCCTGGTCCACCCGGCATGTCAGTCAGCACTCTGGCCTTCATCACGAGAGCTCCGCAGCCGTGGCTAG
GATTCCACTTCCTGTGTCATGACCTCAGGAAATAAACGTCCTTGACTTTATAAAAGCCAAACTAGCTGACGTGGTGGACAGTGAGGCGCT
GCAGGTATACATGAAACCCCCAGCACACGAAGAGGCCAAGGCACCTTCCAGAGGCTTTGTGGTGCGGGACGCACCCTGGACCGCCAGCAG
CAGTGAGAAGGTGGACATTCGCTTCCCACAGAGCGGAGCCCCAGACCCCAACTGCGTCACTGTGACGGGGCTCCCAGAGAATGTGGAGGA
AGCCATCGACCACATCCTCAATCTGGAGGAGGAATACCCCCAGGACCAAATTACCATCACAGGGTACGAAAAGAACACAGAAGCTGCCAG
GGATGCTATACTGAGAATTGTGGGTGAACTTGAGCAGATGGTTTCTGAGGACGTCCCGCTGGACCACCGCGTTCACGCCCGCATCATTGG
TGCCCGCGGCAAAGCCATTCGCAAAATCATGGACGAATTCAAGGCTTTAAGGAGTTTTAAGCTGAGTGTCACTGTAGACCCCAAATACCA
TCCCAAGATTATCGGGAGAAAGGGGGCAGTAATTACCCAAATCCGGTTGGAGCATGACGTGAACATCCAGTTTCCTGATAAGGACGATGG
GAACCAGGTGAACATACATGTCCCGGCACCTGAGCTGCAGTCTGACATCATCGCCATCACGGGCCTCGCTGCAAATTTGGACCGGGCCAA
GGCTGGACTGCTGGAGCGTGTGAAGGAGCTACAGGCCGAGCAGGAGGACCGGGCATTGGTTCCTGTCACCATTGAAGTAGAGGTGCCCTT
TGACCTTCACCGTTACGTTATTGGGCAGAAAGGAAGTGGGATCCGCAAGATGATGGATGAGTTTGAGTTCACAGTACAGAGCCAGTTGTC
CAGGAGAATGGGGACGAAGCTGGGGAGGGGAGAGAGGCTAAAGATTGTGACCCCGGCTCTCCAAGGAGGTGTGACATCATCATCATCTCT
GGCCGGAAAGAAAAGTGTGAGGCTGCCAAGGAAGCTCTGGAGGAAGCTCAGGTGACATTAGAATGTGCTATACCCCAGAAATTCCATCGA
TCTGTCATGGGCCCCAAAGGTTCCAGAATCCAGCAGATTACTCGGGATTTCAGTGTTCAAATTAAATTCCCAGACAGAGAGGAGAACGCA
GGATAATGTGGTGGAAGACTCCATGCTGGTGGACCCCAAGCACCACCGCCACTTCGTCATCCGCAGAGGCCAGGTCTTGCGGGAGATTGC
TGAAGAGTATGGCGGGGTGATGGTCAGCTTCCCACGCTCTGGCACACAGAGCGACAAAGTCACCCTCAAGGGCGCCAAGGACTGTGTGGA
GGCAGCCAAGAAACGCATTCAGGAGATCATTGAGGACCTGCAAACCAAGAGTTTCACTGTTGACATCCGCGCCAAGCCAGAATACCACAA
ATTCCTCATCGGCAAGGGGGGCGGCAAAATTCGCAAGGTGCGCGACAGCACTGGAGCACGTGTCATCTTCCCTGCGGCTGAGGACAAGGA
CCAGGACCTGATCACCATCATTGGAAAGGAGGACGCCGTCCGAGAGGCACAGAAGGAGCTGGAGGCCTTGATCCAAAACCTGGCCAACAT
AGCCGAGGTAGAGGTCTCCATCCCTGCCAAGCTGCACAACTCCCTCATTGGCACCAAGGGCCGTCTGATCCGCTCCATCATGGAGGAGTG
CGGCGGGGTCCACATTCACTTTCCCGTGGAAGGTTCAGGAAGCGACACCGTTGTTATCAGGGGCCCTTCCTCGGATGTGGAGAAGGCCAA
GAAGCAGCTCCTGCATCTGGCGGAGGAGAAGATTCGTGAAGAAAGCAACACCAAAATCGACCTTCCAGCAGAGAATAGCAATTCAGAGAC
CATTATCATCACAGGCAAGCGAGCCAACTGCGAAGCTGCCCGGAGCAGGATTCTGTCTATTCAGAAAGACCTGGTGGAAAATAGCTATTC
AATTTCTGTTCCGATCTTCAAACAGTTTCACAAGAATATCATTGGGAAAGGAGGCGCAAACATTAAAAAGGTCATCATTAACTTTCCAGA
CCCAGCACAAAAAAGTGACATTGTCCAGCTCAGAGGACCTAAGAATGAGGTGGAAAAATGCACAAAATACATGCAGAAGATGGTGGCAGA
TCTGGAAAATGAGCGTACCAAGGATCTAATCATTGAGCAAAGATTTCATCGCACAATCATTGGGCAGAAGGGTGAACGGATCCGTGAAAT
TCGTGACAAATTCCCAGAGTAAACAGAATCAAAGACCAGTACAAGGTGTCCGTGCGCATCCCTCCTGACAGTGAGAAGAGCAATTTGATC
CGCATCGAGGGGGACCCACAGGGCGTGCAGCAGGCCAAGCGAGAGCTGCTGGAGCTTGCATCTCGCATGATTAACCGGATGGACTATGTG
GAGATCAACATCGACCACAAGTTCCACAGGCACCTCATTGGGAAGAGCGGTGCCAACAGTTCACATCGAGTTCACAGAGGGCGAAGACAA
GATCACCCTGGAGGGCCCTACAGAGGATGTCAATGTGGCCCAGGAACAGATAGAAGGCATGGTCAAAGATTTGGCCAATAGCTTCACCGT
CTCCTCTGTCGCCGCCCCTTCCTGGCTTCACCGTTTCATCATTGGCAAGAAAGGGCAGAACCTGGCCAAAATCACTCAGCAGATGCCAAA
GAAAAAGAAGACTACAACCATTGCAGTGGAAGTGAAGAAATCCCAACACAAGTATGTCATTGGGCCCAAGGGCAATTCATTGCAGGAGAT
CCTTGAGAGAACTGGAGTTTCCGTTGAGATCCCACCCTCAGACAGCATCTCTGAGACTGTAATACTTCGAGGCGAACCTGAAAAGTTAGG
TCAGGCGTTGACTGAAGTCTATGCCAAGGACAAACGTGCTGTGGAGAGGCTAGAAGTAGAAAAGGCATTCCACCCCTTCATCGCTGGGCC
GTATAATAGACTGGTTGGCGAGATCATGCAGGAGACAGGCACGCGCATCAACATCCCCCCACCCAGCGTGAACCGGACAGAGATTGTCTT
CACTGGAGAGAAGGAACAGTTGGCTCAGGCTGTGGCTCGCATCAAGAAGATTTATGAGGAGAAGGCCTCAGCAACTGTTGCCATTCCCAA
AGAACACCATCGCTTTGTTATTGGCAAAAATGGAGAGAAACTGCAAGACTTGGAGCTAAAAACTGCAACCAAAATCCAGATCCCACGCCC
AGATGACCCCAGCAATCAGATCAAGATCACTGGCACCAAAGAGGGCATCGAGAAAGCTCGCCATGAAGTCTTACTCATCTCTGCCGAGCA
GAAGCAAAAATCTGCCTTGAGATCATGCAGAGAACTGGTGCTCACTTGGAGCTGTCTTTGGCCAAAGACCAAGGCCTCTCCATCATGGTG

>50240_50240_3_LSR-HDLBP_LSR_chr19_35758865_ENST00000354900_HDLBP_chr2_242202277_ENST00000391976_length(amino acids)=647AA_BP=
MKACPLSTSFTLIKTSRMQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGLGSHPAAAGRDAVV
FVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPY
VECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLDWLFVVVVCLAAFL
IFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDR
SSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPAL
TPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRD
FPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASR

--------------------------------------------------------------
>50240_50240_4_LSR-HDLBP_LSR_chr19_35758865_ENST00000354900_HDLBP_chr2_242202277_ENST00000427183_length(transcript)=5786nt_BP=2105nt
CGGGTGGAGTGTGGCTCGGAGGACCGCGGCGGGTCAAGCACCTTTCTCCCCCATATCTGAAAGCATGCCCTTTGTCCACGTCGTTTACGC
TCATTAAAACTTCCAGAATGCAACAGGACGGACTTGGAGTAGGGACAAGGAACGGAAGTGGGAAGGGGAGGAGCGTGCACCCCTCCTGGC
CTTGGTGCGCGCCGCGCCCCCTAAGGTACTTTGGAAGGGACGCGCGGGCCAGACGCGCCCAGACGGCCGCGATGGCGCTGTTGGCCGGCG
GGCTCTCCAGAGGGCTGGGCTCCCACCCGGCCGCCGCAGGCCGGGACGCGGTCGTCTTCGTGTGGCTTCTGCTTAGCACCTGGTGCACAG
CTCCTGCCAGGGCCATCCAGGTGACCGTGTCCAACCCCTACCACGTGGTGATCCTCTTCCAGCCTGTGACCCTGCCCTGTACCTACCAGA
TGACCTCGACCCCCACGCAACCCATCGTCATCTGGAAGTACAAGTCTTTCTGCCGGGACCGCATCGCCGATGCCTTCTCCCCGGCCAGCG
TCGACAACCAGCTCAATGCCCAGCTGGCAGCCGGGAACCCAGGCTACAACCCCTACGTTGAGTGCCAGGACAGCGTGCGCACCGTCAGGG
TCGTGGCCACCAAGCAGGGCAACGCTGTGACCCTGGGAGATTACTACCAGGGCCGGAGGATTACCATCACCGGAAATGCTGACCTGACCT
TTGACCAGACGGCGTGGGGGGACAGTGGTGTGTATTACTGCTCCGTGGTCTCAGCCCAGGACCTCCAGGGGAACAATGAGGCCTACGCAG
AGCTCATCGTCCTTGACTGGCTCTTCGTGGTTGTGGTATGCCTGGCTGCCTTCCTCATCTTCCTCCTCCTGGGCATCTGCTGGTGCCAGT
GCTGCCCGCACACTTGCTGCTGCTACGTCAGGTGCCCCTGCTGCCCAGACAAGTGCTGCTGCCCCGAGGCCCTGTATGCCGCCGGCAAAG
CAGCCACCTCAGGTGTTCCCAGCATTTATGCCCCCAGCACCTATGCCCACCTGTCTCCCGCCAAGACCCCACCCCCACCAGCTATGATTC
CCATGGGCCCTGCCTACAACGGGTACCCTGGAGGATACCCTGGAGACGTTGACAGGAGTAGCTCAGCTGGTGGCCAAGGCTCCTATGTAC
CCCTGCTTCGGGACACGGACAGCAGTGTGGCCTCTGAAGTCCGCAGTGGCTACAGGATTCAGGCCAGCCAGCAGGACGACTCCATGCGGG
TCCTGTACTACATGGAGAAGGAGCTGGCCAACTTCGACCCTTCTCGACCTGGCCCCCCCAGTGGCCGTGTGGAGCGGGCCATGAGTGAAG
TCACCTCCCTCCACGAGGACGACTGGCGATCTCGGCCTTCCCGGGGCCCTGCCCTCACCCCGATCCGGGATGAGGAGTGGGGTGGCCACT
CCCCCCGGAGTCCCAGGGGATGGGACCAGGAGCCCGCCAGGGAGCAGGCAGGCGGGGGCTGGCGGGCCAGGCGGCCCCGGGCCCGCTCCG
TGGACGCCCTGGACGACCTCACCCCGCCGAGCACCGCCGAGTCAGGGAGCAGGTCTCCCACGAGTAATGGTGGGAGAAGCCGGGCCTACA
TGCCCCCGCGGAGCCGCAGCCGGGACGACCTCTATGACCAAGACGACTCGAGGGACTTCCCACGCTCCCGGGACCCCCACTACGACGACT
TCAGGTCTCGGGAGCGCCCTCCTGCCGACCCCAGGTCCCACCACCACCGTACCCGGGACCCTCGGGACAACGGCTCCAGGTCCGGGGACC
TCCCCTATGATGGGCGGCTACTGGAGGAGGCTGTGAGGAAGAAGGGGTCGGAGGAGAGGAGGAGACCCCACAAGGAGGAGGAGGAAGAGG
CCTACTACCCGCCCGCGCCGCCCCCGTACTCGGAGACCGACTCGCAGGCGTCCCGAGAGCGCAGGCTCAAGAAGAACTTGGCCCTGAGTC
GGGAAAGTTTAGTCGTCTGATCTGACGTTTTCTACGTAGCTTTTGTATTTTTTTTTTTAATTTGAAGGAACACTGATGAAGCCCTGCCAT
ACCCCTCCCGAGTCTAATAAAACGTATAATCACAAGCTCCTGACATGAGCAGCTCTGAGGAATTTCCCAGCTTTGGGGCTCAGGTGGCTC
CCAAGACCCTCCCTTGGGGCCCCAAACGATAATGATCAAAAAGAACAGAACCCTCTCCAGCCTGCTGACCCAAACCCAACCACACAATGG
TTTGTCTCAATCTGACCCAGCGGCTGGACCCTCCGTAAATTGTTGACGCTCTTCCCCCTTCCCGAGGTCCCGCAGGGAGCCTAGCGCCTG
GCTGTGTGTGCGGCCGCTCCTCCAGGCCTGGCCGTGCCCGCTCAGGACCTGCTCCACTGTTTAACACTAAACCAAGGTCATGAGCATTCG
TGCTAAGATAACAGACTCCAGCTCCTGGTCCACCCGGCATGTCAGTCAGCACTCTGGCCTTCATCACGAGAGCTCCGCAGCCGTGGCTAG
GATTCCACTTCCTGTGTCATGACCTCAGGAAATAAACGTCCTTGACTTTATCTAGCTGACGTGGTGGACAGTGAGGCGCTGCAGGTATAC
ATGAAACCCCCAGCACACGAAGAGGCCAAGGCACCTTCCAGAGGCTTTGTGGTGCGGGACGCACCCTGGACCGCCAGCAGCAGTGAGAAG
GTGGACATTCGCTTCCCACAGAGCGGAGCCCCAGACCCCAACTGCGTCACTGTGACGGGGCTCCCAGAGAATGTGGAGGAAGCCATCGAC
CACATCCTCAATCTGGAGGAGGAATACCCCCAGGACCAAATTACCATCACAGGGTACGAAAAGAACACAGAAGCTGCCAGGGATGCTATA
CTGAGAATTGTGGGTGAACTTGAGCAGATGGTTTCTGAGGACGTCCCGCTGGACCACCGCGTTCACGCCCGCATCATTGGTGCCCGCGGC
AAAGCCATTCGCAAAATCATGGACGAATTCAAGGCTTTAAGGAGTTTTAAGCTGAGTGTCACTGTAGACCCCAAATACCATCCCAAGATT
ATCGGGAGAAAGGGGGCAGTAATTACCCAAATCCGGTTGGAGCATGACGTGAACATCCAGTTTCCTGATAAGGACGATGGGAACCAGGTG
AACATACATGTCCCGGCACCTGAGCTGCAGTCTGACATCATCGCCATCACGGGCCTCGCTGCAAATTTGGACCGGGCCAAGGCTGGACTG
CTGGAGCGTGTGAAGGAGCTACAGGCCGAGCAGGAGGACCGGGCATTGGTTCCTGTCACCATTGAAGTAGAGGTGCCCTTTGACCTTCAC
CGTTACGTTATTGGGCAGAAAGGAAGTGGGATCCGCAAGATGATGGATGAGTTTGAGTTCACAGTACAGAGCCAGTTGTCCAGGAGAATG
GGGACGAAGCTGGGGAGGGGAGAGAGGCTAAAGATTGTGACCCCGGCTCTCCAAGGAGGTGTGACATCATCATCATCTCTGGCCGGAAAG
AAAAGTGTGAGGCTGCCAAGGAAGCTCTGGAGGAAGCTCAGGTGACATTAGAATGTGCTATACCCCAGAAATTCCATCGATCTGTCATGG
GCCCCAAAGGTTCCAGAATCCAGCAGATTACTCGGGATTTCAGTGTTCAAATTAAATTCCCAGACAGAGAGGAGAACGCAGGATAATGTG
GTGGAAGACTCCATGCTGGTGGACCCCAAGCACCACCGCCACTTCGTCATCCGCAGAGGCCAGGTCTTGCGGGAGATTGCTGAAGAGTAT
GGCGGGGTGATGGTCAGCTTCCCACGCTCTGGCACACAGAGCGACAAAGTCACCCTCAAGGGCGCCAAGGACTGTGTGGAGGCAGCCAAG
AAACGCATTCAGGAGATCATTGAGGACCTGCAAACCAAGAGTTTCACTGTTGACATCCGCGCCAAGCCAGAATACCACAAATTCCTCATC
GGCAAGGGGGGCGGCAAAATTCGCAAGGTGCGCGACAGCACTGGAGCACGTGTCATCTTCCCTGCGGCTGAGGACAAGGACCAGGACCTG
ATCACCATCATTGGAAAGGAGGACGCCGTCCGAGAGGCACAGAAGGAGCTGGAGGCCTTGATCCAAAACCTGGCCAACATAGCCGAGGTA
GAGGTCTCCATCCCTGCCAAGCTGCACAACTCCCTCATTGGCACCAAGGGCCGTCTGATCCGCTCCATCATGGAGGAGTGCGGCGGGGTC
CACATTCACTTTCCCGTGGAAGGTTCAGGAAGCGACACCGTTGTTATCAGGGGCCCTTCCTCGGATGTGGAGAAGGCCAAGAAGCAGCTC
CTGCATCTGGCGGAGGAGAAGATTCGTGAAGAAAGCAACACCAAAATCGACCTTCCAGCAGAGAATAGCAATTCAGAGACCATTATCATC
ACAGGCAAGCGAGCCAACTGCGAAGCTGCCCGGAGCAGGATTCTGTCTATTCAGAAAGACCTGGTGGAAAATAGCTATTCAATTTCTGTT
CCGATCTTCAAACAGTTTCACAAGAATATCATTGGGAAAGGAGGCGCAAACATTAAAAAGGTCATCATTAACTTTCCAGACCCAGCACAA
AAAAGTGACATTGTCCAGCTCAGAGGACCTAAGAATGAGGTGGAAAAATGCACAAAATACATGCAGAAGATGGTGGCAGATCTGGAAAAT
GAGCGTACCAAGGATCTAATCATTGAGCAAAGATTTCATCGCACAATCATTGGGCAGAAGGGTGAACGGATCCGTGAAATTCGTGACAAA
TTCCCAGAGTAAACAGAATCAAAGACCAGTACAAGGTGTCCGTGCGCATCCCTCCTGACAGTGAGAAGAGCAATTTGATCCGCATCGAGG
GGGACCCACAGGGCGTGCAGCAGGCCAAGCGAGAGCTGCTGGAGCTTGCATCTCGCATGATTAACCGGATGGACTATGTGGAGATCAACA
TCGACCACAAGTTCCACAGGCACCTCATTGGGAAGAGCGGTGCCAACAGTTCACATCGAGTTCACAGAGGGCGAAGACAAGATCACCCTG
GAGGGCCCTACAGAGGATGTCAATGTGGCCCAGGAACAGATAGAAGGCATGGTCAAAGATTTGGCCAATAGCTTCACCGTCTCCTCTGTC
GCCGCCCCTTCCTGGCTTCACCGTTTCATCATTGGCAAGAAAGGGCAGAACCTGGCCAAAATCACTCAGCAGATGCCAAAGGACAAACGT
GCTGTGGAGAGGCTAGAAGTAGAAAAGGCATTCCACCCCTTCATCGCTGGGCCGTATAATAGACTGGTTGGCGAGATCATGCAGGAGACA
GGCACGCGCATCAACATCCCCCCACCCAGCGTGAACCGGACAGAGATTGTCTTCACTGGAGAGAAGGAACAGTTGGCTCAGGCTGTGGCT
CGCATCAAGAAGATTTATGAGGAGAAGGCCTCAGCAACTGTTGCCATTCCCAAAGAACACCATCGCTTTGTTATTGGCAAAAATGGAGAG
AAACTGCAAGACTTGGAGCTAAAAACTGCAACCAAAATCCAGATCCCACGCCCAGATGACCCCAGCAATCAGATCAAGATCACTGGCACC
AAAGAGGGCATCGAGAAAGCTCGCCATGAAGTCTTACTCATCTCTGCCGAGCAGAAGCAAAAATCTGCCTTGAGATCATGCAGAGAACTG
GTGCTCACTTGGAGCTGTCTTTGGCCAAAGACCAAGGCCTCTCCATCATGGTGTCAGGAAAGCTGGATGCTGTCATGAAAGCTCGGAAGG

>50240_50240_4_LSR-HDLBP_LSR_chr19_35758865_ENST00000354900_HDLBP_chr2_242202277_ENST00000427183_length(amino acids)=647AA_BP=
MKACPLSTSFTLIKTSRMQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGLGSHPAAAGRDAVV
FVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPY
VECQDSVRTVRVVATKQGNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLDWLFVVVVCLAAFL
IFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDR
SSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPAL
TPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRD
FPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for LSR-HDLBP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LSR-HDLBP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LSR-HDLBP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource