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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LTA4H-SLC25A24 (FusionGDB2 ID:50256)

Fusion Gene Summary for LTA4H-SLC25A24

check button Fusion gene summary
Fusion gene informationFusion gene name: LTA4H-SLC25A24
Fusion gene ID: 50256
HgeneTgene
Gene symbol

LTA4H

SLC25A24

Gene ID

4048

29957

Gene nameleukotriene A4 hydrolasesolute carrier family 25 member 24
Synonyms-APC1|SCAMC-1|SCAMC1
Cytomap

12q23.1

1p13.3

Type of geneprotein-codingprotein-coding
Descriptionleukotriene A-4 hydrolaseLTA-4 hydrolasetesticular secretory protein Li 27calcium-binding mitochondrial carrier protein SCaMC-1calcium-binding transportermitochondrial ATP-Mg/Pi carrier protein 1mitochondrial Ca(2+)-dependent solute carrier protein 1short calcium-binding mitochondrial carrier 1small calcium-binding mitocho
Modification date2020031320200313
UniProtAcc

P09960

.
Ensembl transtripts involved in fusion geneENST00000228740, ENST00000413268, 
ENST00000552789, ENST00000548375, 
ENST00000569674, ENST00000370041, 
ENST00000565488, 
Fusion gene scores* DoF score9 X 11 X 4=3964 X 3 X 4=48
# samples 115
** MAII scorelog2(11/396*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/48*10)=0.0588936890535686
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: LTA4H [Title/Abstract] AND SLC25A24 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLTA4H(96402872)-SLC25A24(108686332), # samples:2
Anticipated loss of major functional domain due to fusion event.LTA4H-SLC25A24 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
LTA4H-SLC25A24 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
LTA4H-SLC25A24 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
LTA4H-SLC25A24 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneLTA4H

GO:0019370

leukotriene biosynthetic process

9774412|15078870

HgeneLTA4H

GO:0043171

peptide catabolic process

9774412|15078870|18804029


check buttonFusion gene breakpoints across LTA4H (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC25A24 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4J6-01ALTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
ChimerDB4STADTCGA-BR-A4J6LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-


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Fusion Gene ORF analysis for LTA4H-SLC25A24

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000228740ENST00000569674LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5CDS-intronENST00000228740ENST00000569674LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-
5CDS-intronENST00000413268ENST00000569674LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5CDS-intronENST00000413268ENST00000569674LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-
5CDS-intronENST00000552789ENST00000569674LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5CDS-intronENST00000552789ENST00000569674LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-
5UTR-3CDSENST00000548375ENST00000370041LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5UTR-3CDSENST00000548375ENST00000370041LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-
5UTR-3CDSENST00000548375ENST00000565488LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5UTR-3CDSENST00000548375ENST00000565488LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-
5UTR-intronENST00000548375ENST00000569674LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
5UTR-intronENST00000548375ENST00000569674LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-
Frame-shiftENST00000413268ENST00000370041LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
Frame-shiftENST00000413268ENST00000370041LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-
Frame-shiftENST00000413268ENST00000565488LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
Frame-shiftENST00000413268ENST00000565488LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-
In-frameENST00000228740ENST00000370041LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
In-frameENST00000228740ENST00000370041LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-
In-frameENST00000228740ENST00000565488LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
In-frameENST00000228740ENST00000565488LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-
In-frameENST00000552789ENST00000370041LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
In-frameENST00000552789ENST00000370041LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-
In-frameENST00000552789ENST00000565488LTA4Hchr12

96402872

-SLC25A24chr1

108686332

-
In-frameENST00000552789ENST00000565488LTA4Hchr12

96402871

-SLC25A24chr1

108686332

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000228740LTA4Hchr1296402872-ENST00000565488SLC25A24chr1108686332-469715761422079645
ENST00000228740LTA4Hchr1296402872-ENST00000370041SLC25A24chr1108686332-391015761422079645
ENST00000552789LTA4Hchr1296402872-ENST00000565488SLC25A24chr1108686332-45851464931967624
ENST00000552789LTA4Hchr1296402872-ENST00000370041SLC25A24chr1108686332-37981464931967624
ENST00000228740LTA4Hchr1296402871-ENST00000565488SLC25A24chr1108686332-469715761422079645
ENST00000228740LTA4Hchr1296402871-ENST00000370041SLC25A24chr1108686332-391015761422079645
ENST00000552789LTA4Hchr1296402871-ENST00000565488SLC25A24chr1108686332-45851464931967624
ENST00000552789LTA4Hchr1296402871-ENST00000370041SLC25A24chr1108686332-37981464931967624

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000228740ENST00000565488LTA4Hchr1296402872-SLC25A24chr1108686332-0.0002576940.9997423
ENST00000228740ENST00000370041LTA4Hchr1296402872-SLC25A24chr1108686332-0.0002395620.99976045
ENST00000552789ENST00000565488LTA4Hchr1296402872-SLC25A24chr1108686332-0.0002750830.9997249
ENST00000552789ENST00000370041LTA4Hchr1296402872-SLC25A24chr1108686332-0.0002648580.9997352
ENST00000228740ENST00000565488LTA4Hchr1296402871-SLC25A24chr1108686332-0.0002576940.9997423
ENST00000228740ENST00000370041LTA4Hchr1296402871-SLC25A24chr1108686332-0.0002395620.99976045
ENST00000552789ENST00000565488LTA4Hchr1296402871-SLC25A24chr1108686332-0.0002750830.9997249
ENST00000552789ENST00000370041LTA4Hchr1296402871-SLC25A24chr1108686332-0.0002648580.9997352

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Fusion Genomic Features for LTA4H-SLC25A24


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for LTA4H-SLC25A24


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:96402872/chr1:108686332)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LTA4H

P09960

.
FUNCTION: Bifunctional zinc metalloenzyme that comprises both epoxide hydrolase (EH) and aminopeptidase activities. Acts as an epoxide hydrolase to catalyze the conversion of LTA4 to the proinflammatory mediator leukotriene B4 (LTB4) (PubMed:11917124, PubMed:12207002, PubMed:15078870, PubMed:18804029, PubMed:1897988, PubMed:1975494, PubMed:2244921). Has also aminopeptidase activity, with high affinity for N-terminal arginines of various synthetic tripeptides (PubMed:20813919, PubMed:18804029). In addition to its proinflammatory EH activity, may also counteract inflammation by its aminopeptidase activity, which inactivates by cleavage another neutrophil attractant, the tripeptide Pro-Gly-Pro (PGP), a bioactive fragment of collagen generated by the action of matrix metalloproteinase-9 (MMP9) and prolylendopeptidase (PREPL) (PubMed:20813919, PubMed:24591641). Involved also in the biosynthesis of resolvin E1 and 18S-resolvin E1 from eicosapentaenoic acid, two lipid mediators that show potent anti-inflammatory and pro-resolving actions (PubMed:21206090). {ECO:0000269|PubMed:11917124, ECO:0000269|PubMed:12207002, ECO:0000269|PubMed:15078870, ECO:0000269|PubMed:18804029, ECO:0000269|PubMed:1897988, ECO:0000269|PubMed:1975494, ECO:0000269|PubMed:20813919, ECO:0000269|PubMed:21206090, ECO:0000269|PubMed:2244921, ECO:0000269|PubMed:24591641}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000228740-1519135_137478612.0RegionSubstrate binding
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000228740-1519267_272478612.0RegionSubstrate binding
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000228740-1519362_365478612.0RegionInhibitor ARM1 binding
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000413268-1518135_137454489.6666666666667RegionSubstrate binding
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000413268-1518267_272454489.6666666666667RegionSubstrate binding
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000413268-1518362_365454489.6666666666667RegionInhibitor ARM1 binding
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000552789-1519135_137454588.0RegionSubstrate binding
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000552789-1519267_272454588.0RegionSubstrate binding
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000552789-1519362_365454588.0RegionInhibitor ARM1 binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000228740-1519135_137478612.0RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000228740-1519267_272478612.0RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000228740-1519362_365478612.0RegionInhibitor ARM1 binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000413268-1518135_137454489.6666666666667RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000413268-1518267_272454489.6666666666667RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000413268-1518362_365454489.6666666666667RegionInhibitor ARM1 binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000552789-1519135_137454588.0RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000552789-1519267_272454588.0RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000552789-1519362_365454588.0RegionInhibitor ARM1 binding
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610383_471291459.0RepeatNote=Solcar 3
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610383_471310478.0RepeatNote=Solcar 3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610383_471291459.0RepeatNote=Solcar 3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610383_471310478.0RepeatNote=Solcar 3
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610310_345291459.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610366_388291459.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610407_445291459.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610466_477291459.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610310_345310478.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610366_388310478.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610407_445310478.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610466_477310478.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610310_345291459.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610366_388291459.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610407_445291459.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610466_477291459.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610310_345310478.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610366_388310478.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610407_445310478.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610466_477310478.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610296_309291459.0TransmembraneHelical%3B Name%3D3
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610346_365291459.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610389_406291459.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610446_465291459.0TransmembraneHelical%3B Name%3D6
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610346_365310478.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610389_406310478.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610446_465310478.0TransmembraneHelical%3B Name%3D6
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610296_309291459.0TransmembraneHelical%3B Name%3D3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610346_365291459.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610389_406291459.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610446_465291459.0TransmembraneHelical%3B Name%3D6
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610346_365310478.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610389_406310478.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610446_465310478.0TransmembraneHelical%3B Name%3D6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000228740-1519564_566478612.0RegionSubstrate binding
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000413268-1518564_566454489.6666666666667RegionSubstrate binding
HgeneLTA4Hchr12:96402871chr1:108686332ENST00000552789-1519564_566454588.0RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000228740-1519564_566478612.0RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000413268-1518564_566454489.6666666666667RegionSubstrate binding
HgeneLTA4Hchr12:96402872chr1:108686332ENST00000552789-1519564_566454588.0RegionSubstrate binding
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610135_146291459.0Calcium bindingNote=4
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000037004161032_43291459.0Calcium bindingNote=1
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000037004161068_79291459.0Calcium bindingNote=2
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000037004161099_110291459.0Calcium bindingNote=3
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610135_146310478.0Calcium bindingNote=4
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000056548861032_43310478.0Calcium bindingNote=1
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000056548861068_79310478.0Calcium bindingNote=2
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000056548861099_110310478.0Calcium bindingNote=3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610135_146291459.0Calcium bindingNote=4
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000037004161032_43291459.0Calcium bindingNote=1
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000037004161068_79291459.0Calcium bindingNote=2
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000037004161099_110291459.0Calcium bindingNote=3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610135_146310478.0Calcium bindingNote=4
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000056548861032_43310478.0Calcium bindingNote=1
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000056548861068_79310478.0Calcium bindingNote=2
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000056548861099_110310478.0Calcium bindingNote=3
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610122_157291459.0DomainEF-hand 4
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000037004161019_54291459.0DomainEF-hand 1
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000037004161055_88291459.0DomainEF-hand 2
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000037004161086_121291459.0DomainEF-hand 3
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610122_157310478.0DomainEF-hand 4
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000056548861019_54310478.0DomainEF-hand 1
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000056548861055_88310478.0DomainEF-hand 2
TgeneSLC25A24chr12:96402871chr1:108686332ENST0000056548861086_121310478.0DomainEF-hand 3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610122_157291459.0DomainEF-hand 4
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000037004161019_54291459.0DomainEF-hand 1
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000037004161055_88291459.0DomainEF-hand 2
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000037004161086_121291459.0DomainEF-hand 3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610122_157310478.0DomainEF-hand 4
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000056548861019_54310478.0DomainEF-hand 1
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000056548861055_88310478.0DomainEF-hand 2
TgeneSLC25A24chr12:96402872chr1:108686332ENST0000056548861086_121310478.0DomainEF-hand 3
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610192_278291459.0RepeatNote=Solcar 1
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610286_371291459.0RepeatNote=Solcar 2
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610192_278310478.0RepeatNote=Solcar 1
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610286_371310478.0RepeatNote=Solcar 2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610192_278291459.0RepeatNote=Solcar 1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610286_371291459.0RepeatNote=Solcar 2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610192_278310478.0RepeatNote=Solcar 1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610286_371310478.0RepeatNote=Solcar 2
TgeneSLC25A24chr12:96402871chr1:108686332ENST000003700416101_197291459.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610216_252291459.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610273_295291459.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402871chr1:108686332ENST000005654886101_197310478.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610216_252310478.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610273_295310478.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST000003700416101_197291459.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610216_252291459.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610273_295291459.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST000005654886101_197310478.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610216_252310478.0Topological domainMitochondrial matrix
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610273_295310478.0Topological domainMitochondrial intermembrane
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610198_215291459.0TransmembraneHelical%3B Name%3D1
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000370041610253_272291459.0TransmembraneHelical%3B Name%3D2
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610198_215310478.0TransmembraneHelical%3B Name%3D1
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610253_272310478.0TransmembraneHelical%3B Name%3D2
TgeneSLC25A24chr12:96402871chr1:108686332ENST00000565488610296_309310478.0TransmembraneHelical%3B Name%3D3
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610198_215291459.0TransmembraneHelical%3B Name%3D1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000370041610253_272291459.0TransmembraneHelical%3B Name%3D2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610198_215310478.0TransmembraneHelical%3B Name%3D1
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610253_272310478.0TransmembraneHelical%3B Name%3D2
TgeneSLC25A24chr12:96402872chr1:108686332ENST00000565488610296_309310478.0TransmembraneHelical%3B Name%3D3


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Fusion Gene Sequence for LTA4H-SLC25A24


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>50256_50256_1_LTA4H-SLC25A24_LTA4H_chr12_96402871_ENST00000228740_SLC25A24_chr1_108686332_ENST00000370041_length(transcript)=3910nt_BP=1576nt
AAGAAACTTCCTTTCCCGGCGTGCACCGCGAATCCCTCCTCCTCTTCTTTACCTCTCTCCCTCCTCCTCAGGTTCTCTATCGACGAGTCT
GGTAGCTGAGCGTTGGGCTGTAGGTCGCTGTGCTGTGTGATCCCCCAGAGCCATGCCCGAGATAGTGGATACCTGTTCGTTGGCCTCTCC
GGCTTCCGTCTGCCGGACCAAGCACCTGCACCTGCGCTGCAGCGTCGACTTTACTCGCCGGACGCTGACCGGGACTGCTGCTCTCACGGT
CCAGTCTCAGGAGGACAATCTGCGCAGCCTGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAA
ATATGCTCTTGGAGAAAGACAAAGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTAT
AGAAATTTCTTTTGAGACCTCTCCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTT
TAGTCAGTGCCAGGCCATCCACTGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGT
CCCTAAAGAACTGGTGGCACTTATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCAT
CCAAAAAGTTCCAATACCCTGCTACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTC
TGAGAAAGAGCAGGTGGAAAAGTCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGT
ATGGGGACAGTATGACCTATTGGTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCT
ACTGGCAGGCGACAAGTCACTCTCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGA
TCACTTTTGGTTAAATGAGGGACATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGC
TCTGGGAGGATGGGGAGAACTACAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATAT
AGACCCTGATGTAGCTTATTCTTCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGAT
TTTCCTAGGATTCTTAAAAGCTTATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTT
TAAAGATAAGGTTGATGTTCTCAATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATAT
GACTCTGACAAATGCTTGTATTGCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTC
TGGAATATATGATTGTGCCAAGAAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCAT
ACCTTATGCAGGCATAGATCTTGCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGT
CATGGTGTTGCTGGGATGCGGTGCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGC
TCAAGCCATGTTAGAAGGTTCCCCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAG
AGGCATCACCCCAAACTTCATGAAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAAC
CCAGAAATGATGTTGCATTTTTTGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAA
GTCTATGGCAAAAGAAGCTGCATTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACAC
AGAAATGTTCAAAATCATAGTTTTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCC
CTGAATCCGAAATCTGAAAATGTACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTT
TACGTTTATGCCAGTTCCTTTATATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACC
ATTAATAGAAAATCATTACATTTAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCT
GAATACGAATGAACACAGTGGTGGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTA
CCATTATTTGGTTCCTGGAGTTATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTT
TATCCTGCCATTGCTTTGAAAAGCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTT
TGTTTCCTACCTTTTGAATCAGATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCA
TGAAGTGGATTGATCATGAGCAAATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCAC
AAAGGTGAGAGATACATATTAATAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATA
TACATTCATATTCTCTCTTGCCCCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTT
ACTAAAGCCATTTTTATAGTCAACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTT
TTAATTTAGTTCTTAAACTCATTTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCAT
TTTCTTTATTTGAACCTACCTCTTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCA
TTTATATTAGTTATGTTTGATAAATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAG
TAATATATAAAGTGACAATATTAAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAA
CTTTGAAATTTCAAACTTCTGGAAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTAC
ATCTTGTATCTTTTCCAAAAAATGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTT

>50256_50256_1_LTA4H-SLC25A24_LTA4H_chr12_96402871_ENST00000228740_SLC25A24_chr1_108686332_ENST00000370041_length(amino acids)=645AA_BP=476
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEIS
LPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP
DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGG
MENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET
HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLY
SPGLPPIKPNYDMTLTNACIALSQRWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYW
LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISY

--------------------------------------------------------------
>50256_50256_2_LTA4H-SLC25A24_LTA4H_chr12_96402871_ENST00000228740_SLC25A24_chr1_108686332_ENST00000565488_length(transcript)=4697nt_BP=1576nt
AAGAAACTTCCTTTCCCGGCGTGCACCGCGAATCCCTCCTCCTCTTCTTTACCTCTCTCCCTCCTCCTCAGGTTCTCTATCGACGAGTCT
GGTAGCTGAGCGTTGGGCTGTAGGTCGCTGTGCTGTGTGATCCCCCAGAGCCATGCCCGAGATAGTGGATACCTGTTCGTTGGCCTCTCC
GGCTTCCGTCTGCCGGACCAAGCACCTGCACCTGCGCTGCAGCGTCGACTTTACTCGCCGGACGCTGACCGGGACTGCTGCTCTCACGGT
CCAGTCTCAGGAGGACAATCTGCGCAGCCTGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAA
ATATGCTCTTGGAGAAAGACAAAGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTAT
AGAAATTTCTTTTGAGACCTCTCCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTT
TAGTCAGTGCCAGGCCATCCACTGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGT
CCCTAAAGAACTGGTGGCACTTATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCAT
CCAAAAAGTTCCAATACCCTGCTACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTC
TGAGAAAGAGCAGGTGGAAAAGTCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGT
ATGGGGACAGTATGACCTATTGGTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCT
ACTGGCAGGCGACAAGTCACTCTCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGA
TCACTTTTGGTTAAATGAGGGACATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGC
TCTGGGAGGATGGGGAGAACTACAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATAT
AGACCCTGATGTAGCTTATTCTTCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGAT
TTTCCTAGGATTCTTAAAAGCTTATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTT
TAAAGATAAGGTTGATGTTCTCAATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATAT
GACTCTGACAAATGCTTGTATTGCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTC
TGGAATATATGATTGTGCCAAGAAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCAT
ACCTTATGCAGGCATAGATCTTGCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGT
CATGGTGTTGCTGGGATGCGGTGCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGC
TCAAGCCATGTTAGAAGGTTCCCCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAG
AGGCATCACCCCAAACTTCATGAAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAAC
CCAGAAATGATGTTGCATTTTTTGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAA
GTCTATGGCAAAAGAAGCTGCATTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACAC
AGAAATGTTCAAAATCATAGTTTTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCC
CTGAATCCGAAATCTGAAAATGTACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTT
TACGTTTATGCCAGTTCCTTTATATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACC
ATTAATAGAAAATCATTACATTTAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCT
GAATACGAATGAACACAGTGGTGGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTA
CCATTATTTGGTTCCTGGAGTTATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTT
TATCCTGCCATTGCTTTGAAAAGCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTT
TGTTTCCTACCTTTTGAATCAGATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCA
TGAAGTGGATTGATCATGAGCAAATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCAC
AAAGGTGAGAGATACATATTAATAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATA
TACATTCATATTCTCTCTTGCCCCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTT
ACTAAAGCCATTTTTATAGTCAACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTT
TTAATTTAGTTCTTAAACTCATTTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCAT
TTTCTTTATTTGAACCTACCTCTTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCA
TTTATATTAGTTATGTTTGATAAATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAG
TAATATATAAAGTGACAATATTAAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAA
CTTTGAAATTTCAAACTTCTGGAAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTAC
ATCTTGTATCTTTTCCAAAAAATGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTT
ACTTACAGTTTCTATCAAAAATATATATTTGTTTCTAAAATTACTTGTTTTCCAGTTTTTATTTTTTTTAGAGAAAATTCTTAAGTCTCA
GTTTCCTAATTGAAAAAAAAAAATTATAAATAAAGCAAAAATTGTATCCTACAGCTTAGCTAGCTTAGATGTTTGGCACCAGTTTGAATC
ATGCTTTTTACAGCTGGCTCCATGTAGTCTTTCCAAACATTTTGGCCTTTCCTGAGCAGCCCTTGTAGATATTGTCTGTATGATGCATTT
TGACACAAGGTGATATTTTTTGTGATATCAAAATTCCACATTTACCCATTAGAGTTACAGCCCTGGGGTTCACAGTACCAAGGGGGACCC
AGAGCCTCAGGATTGGCCAGGCTCATTTTGCCGTGGAGTATCAGTTTGTCTTGAAATTGTGGGAAAAAATTCTAAGTTGAATTCACTGGT
AAGTAATTTTTTAAAATTTCATAATGCAGATTACATCCAAAATTTGATTTAAAAATTAAAACATAAGACTGCAGAGAAATTCTGCATTTC
AACTCCAATACTATCCAGACTTCAGAAATAACTTATCAGTTATTTCTGTAAGCTTCTTGCTTACCTGGATACCTGACAGGTGAGATGGCT
GTAGCAGACACTGGCAGTTCCCTGCCCACACACCTGTCCCTGTCCACAGCTGCACAAGGCAGCTCTGTGTGCAATTGCCAGCATCTGCTC
CTCTGTTCTCAGGGAATCTTTGTTAGAAAAATGCTGCCATATTTGTTTCTCACCTATTAGTCTTGTCTCCCAGTCAAGAGAATAAATTTA

>50256_50256_2_LTA4H-SLC25A24_LTA4H_chr12_96402871_ENST00000228740_SLC25A24_chr1_108686332_ENST00000565488_length(amino acids)=645AA_BP=476
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEIS
LPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP
DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGG
MENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET
HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLY
SPGLPPIKPNYDMTLTNACIALSQRWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYW
LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISY

--------------------------------------------------------------
>50256_50256_3_LTA4H-SLC25A24_LTA4H_chr12_96402871_ENST00000552789_SLC25A24_chr1_108686332_ENST00000370041_length(transcript)=3798nt_BP=1464nt
ATGTTTGTCTTTTAAAGCAACAAGGGAAGAGGGCAAGAGGATGCATGGGCTTGGGAGTTTATTTTCTCTCCTCCTGTCTACACCTCCTCT
AATCTGTCTCCCATGCTGCCACAGAGAAATCTTTCTAAAAGACAAGTACCGACCATGCATATCCCAGTTAAGACTCGTCGACTTCTTGCA
GCCTTAAAGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAAATATGCTCTTGGAGAAAGACAA
AGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTATAGAAATTTCTTTTGAGACCTCT
CCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTTTAGTCAGTGCCAGGCCATCCAC
TGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGTCCCTAAAGAACTGGTGGCACTT
ATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCATCCAAAAAGTTCCAATACCCTGC
TACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTCTGAGAAAGAGCAGGTGGAAAAG
TCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGTATGGGGACAGTATGACCTATTG
GTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCTACTGGCAGGCGACAAGTCACTC
TCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAGGGA
CATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGCTCTGGGAGGATGGGGAGAACTA
CAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATATAGACCCTGATGTAGCTTATTCT
TCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGATTTTCCTAGGATTCTTAAAAGCT
TATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTTTAAAGATAAGGTTGATGTTCTC
AATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATATGACTCTGACAAATGCTTGTATT
GCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTCTGGAATATATGATTGTGCCAAG
AAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATAGATCTT
GCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGT
GCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAAGGTTCC
CCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAGAGGCATCACCCCAAACTTCATG
AAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAACCCAGAAATGATGTTGCATTTTT
TGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAAGTCTATGGCAAAAGAAGCTGCA
TTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACACAGAAATGTTCAAAATCATAGTT
TTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCCCTGAATCCGAAATCTGAAAATG
TACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTTTACGTTTATGCCAGTTCCTTTA
TATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACCATTAATAGAAAATCATTACATT
TAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCTGAATACGAATGAACACAGTGGT
GGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTACCATTATTTGGTTCCTGGAGTT
ATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTTTATCCTGCCATTGCTTTGAAAA
GCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTTTGTTTCCTACCTTTTGAATCAG
ATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCATGAAGTGGATTGATCATGAGCA
AATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCACAAAGGTGAGAGATACATATTAA
TAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATATACATTCATATTCTCTCTTGCC
CCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTTACTAAAGCCATTTTTATAGTCA
ACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTTTTAATTTAGTTCTTAAACTCAT
TTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCATTTTCTTTATTTGAACCTACCTC
TTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCATTTATATTAGTTATGTTTGATA
AATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAGTAATATATAAAGTGACAATATT
AAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAACTTTGAAATTTCAAACTTCTGG
AAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTACATCTTGTATCTTTTCCAAAAAA
TGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTTACTTACAGTTTCTATCAAAAAT

>50256_50256_3_LTA4H-SLC25A24_LTA4H_chr12_96402871_ENST00000552789_SLC25A24_chr1_108686332_ENST00000370041_length(amino acids)=624AA_BP=455
MSPMLPQRNLSKRQVPTMHIPVKTRRLLAALKVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSP
KSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCY
LIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLS
NVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSS
VPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIA
LSQRWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA

--------------------------------------------------------------
>50256_50256_4_LTA4H-SLC25A24_LTA4H_chr12_96402871_ENST00000552789_SLC25A24_chr1_108686332_ENST00000565488_length(transcript)=4585nt_BP=1464nt
ATGTTTGTCTTTTAAAGCAACAAGGGAAGAGGGCAAGAGGATGCATGGGCTTGGGAGTTTATTTTCTCTCCTCCTGTCTACACCTCCTCT
AATCTGTCTCCCATGCTGCCACAGAGAAATCTTTCTAAAAGACAAGTACCGACCATGCATATCCCAGTTAAGACTCGTCGACTTCTTGCA
GCCTTAAAGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAAATATGCTCTTGGAGAAAGACAA
AGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTATAGAAATTTCTTTTGAGACCTCT
CCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTTTAGTCAGTGCCAGGCCATCCAC
TGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGTCCCTAAAGAACTGGTGGCACTT
ATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCATCCAAAAAGTTCCAATACCCTGC
TACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTCTGAGAAAGAGCAGGTGGAAAAG
TCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGTATGGGGACAGTATGACCTATTG
GTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCTACTGGCAGGCGACAAGTCACTC
TCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAGGGA
CATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGCTCTGGGAGGATGGGGAGAACTA
CAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATATAGACCCTGATGTAGCTTATTCT
TCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGATTTTCCTAGGATTCTTAAAAGCT
TATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTTTAAAGATAAGGTTGATGTTCTC
AATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATATGACTCTGACAAATGCTTGTATT
GCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTCTGGAATATATGATTGTGCCAAG
AAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATAGATCTT
GCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGT
GCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAAGGTTCC
CCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAGAGGCATCACCCCAAACTTCATG
AAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAACCCAGAAATGATGTTGCATTTTT
TGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAAGTCTATGGCAAAAGAAGCTGCA
TTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACACAGAAATGTTCAAAATCATAGTT
TTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCCCTGAATCCGAAATCTGAAAATG
TACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTTTACGTTTATGCCAGTTCCTTTA
TATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACCATTAATAGAAAATCATTACATT
TAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCTGAATACGAATGAACACAGTGGT
GGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTACCATTATTTGGTTCCTGGAGTT
ATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTTTATCCTGCCATTGCTTTGAAAA
GCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTTTGTTTCCTACCTTTTGAATCAG
ATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCATGAAGTGGATTGATCATGAGCA
AATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCACAAAGGTGAGAGATACATATTAA
TAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATATACATTCATATTCTCTCTTGCC
CCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTTACTAAAGCCATTTTTATAGTCA
ACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTTTTAATTTAGTTCTTAAACTCAT
TTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCATTTTCTTTATTTGAACCTACCTC
TTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCATTTATATTAGTTATGTTTGATA
AATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAGTAATATATAAAGTGACAATATT
AAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAACTTTGAAATTTCAAACTTCTGG
AAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTACATCTTGTATCTTTTCCAAAAAA
TGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTTACTTACAGTTTCTATCAAAAAT
ATATATTTGTTTCTAAAATTACTTGTTTTCCAGTTTTTATTTTTTTTAGAGAAAATTCTTAAGTCTCAGTTTCCTAATTGAAAAAAAAAA
ATTATAAATAAAGCAAAAATTGTATCCTACAGCTTAGCTAGCTTAGATGTTTGGCACCAGTTTGAATCATGCTTTTTACAGCTGGCTCCA
TGTAGTCTTTCCAAACATTTTGGCCTTTCCTGAGCAGCCCTTGTAGATATTGTCTGTATGATGCATTTTGACACAAGGTGATATTTTTTG
TGATATCAAAATTCCACATTTACCCATTAGAGTTACAGCCCTGGGGTTCACAGTACCAAGGGGGACCCAGAGCCTCAGGATTGGCCAGGC
TCATTTTGCCGTGGAGTATCAGTTTGTCTTGAAATTGTGGGAAAAAATTCTAAGTTGAATTCACTGGTAAGTAATTTTTTAAAATTTCAT
AATGCAGATTACATCCAAAATTTGATTTAAAAATTAAAACATAAGACTGCAGAGAAATTCTGCATTTCAACTCCAATACTATCCAGACTT
CAGAAATAACTTATCAGTTATTTCTGTAAGCTTCTTGCTTACCTGGATACCTGACAGGTGAGATGGCTGTAGCAGACACTGGCAGTTCCC
TGCCCACACACCTGTCCCTGTCCACAGCTGCACAAGGCAGCTCTGTGTGCAATTGCCAGCATCTGCTCCTCTGTTCTCAGGGAATCTTTG

>50256_50256_4_LTA4H-SLC25A24_LTA4H_chr12_96402871_ENST00000552789_SLC25A24_chr1_108686332_ENST00000565488_length(amino acids)=624AA_BP=455
MSPMLPQRNLSKRQVPTMHIPVKTRRLLAALKVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSP
KSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCY
LIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLS
NVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSS
VPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIA
LSQRWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA

--------------------------------------------------------------
>50256_50256_5_LTA4H-SLC25A24_LTA4H_chr12_96402872_ENST00000228740_SLC25A24_chr1_108686332_ENST00000370041_length(transcript)=3910nt_BP=1576nt
AAGAAACTTCCTTTCCCGGCGTGCACCGCGAATCCCTCCTCCTCTTCTTTACCTCTCTCCCTCCTCCTCAGGTTCTCTATCGACGAGTCT
GGTAGCTGAGCGTTGGGCTGTAGGTCGCTGTGCTGTGTGATCCCCCAGAGCCATGCCCGAGATAGTGGATACCTGTTCGTTGGCCTCTCC
GGCTTCCGTCTGCCGGACCAAGCACCTGCACCTGCGCTGCAGCGTCGACTTTACTCGCCGGACGCTGACCGGGACTGCTGCTCTCACGGT
CCAGTCTCAGGAGGACAATCTGCGCAGCCTGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAA
ATATGCTCTTGGAGAAAGACAAAGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTAT
AGAAATTTCTTTTGAGACCTCTCCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTT
TAGTCAGTGCCAGGCCATCCACTGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGT
CCCTAAAGAACTGGTGGCACTTATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCAT
CCAAAAAGTTCCAATACCCTGCTACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTC
TGAGAAAGAGCAGGTGGAAAAGTCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGT
ATGGGGACAGTATGACCTATTGGTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCT
ACTGGCAGGCGACAAGTCACTCTCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGA
TCACTTTTGGTTAAATGAGGGACATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGC
TCTGGGAGGATGGGGAGAACTACAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATAT
AGACCCTGATGTAGCTTATTCTTCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGAT
TTTCCTAGGATTCTTAAAAGCTTATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTT
TAAAGATAAGGTTGATGTTCTCAATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATAT
GACTCTGACAAATGCTTGTATTGCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTC
TGGAATATATGATTGTGCCAAGAAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCAT
ACCTTATGCAGGCATAGATCTTGCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGT
CATGGTGTTGCTGGGATGCGGTGCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGC
TCAAGCCATGTTAGAAGGTTCCCCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAG
AGGCATCACCCCAAACTTCATGAAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAAC
CCAGAAATGATGTTGCATTTTTTGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAA
GTCTATGGCAAAAGAAGCTGCATTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACAC
AGAAATGTTCAAAATCATAGTTTTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCC
CTGAATCCGAAATCTGAAAATGTACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTT
TACGTTTATGCCAGTTCCTTTATATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACC
ATTAATAGAAAATCATTACATTTAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCT
GAATACGAATGAACACAGTGGTGGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTA
CCATTATTTGGTTCCTGGAGTTATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTT
TATCCTGCCATTGCTTTGAAAAGCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTT
TGTTTCCTACCTTTTGAATCAGATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCA
TGAAGTGGATTGATCATGAGCAAATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCAC
AAAGGTGAGAGATACATATTAATAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATA
TACATTCATATTCTCTCTTGCCCCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTT
ACTAAAGCCATTTTTATAGTCAACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTT
TTAATTTAGTTCTTAAACTCATTTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCAT
TTTCTTTATTTGAACCTACCTCTTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCA
TTTATATTAGTTATGTTTGATAAATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAG
TAATATATAAAGTGACAATATTAAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAA
CTTTGAAATTTCAAACTTCTGGAAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTAC
ATCTTGTATCTTTTCCAAAAAATGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTT

>50256_50256_5_LTA4H-SLC25A24_LTA4H_chr12_96402872_ENST00000228740_SLC25A24_chr1_108686332_ENST00000370041_length(amino acids)=645AA_BP=476
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEIS
LPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP
DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGG
MENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET
HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLY
SPGLPPIKPNYDMTLTNACIALSQRWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYW
LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISY

--------------------------------------------------------------
>50256_50256_6_LTA4H-SLC25A24_LTA4H_chr12_96402872_ENST00000228740_SLC25A24_chr1_108686332_ENST00000565488_length(transcript)=4697nt_BP=1576nt
AAGAAACTTCCTTTCCCGGCGTGCACCGCGAATCCCTCCTCCTCTTCTTTACCTCTCTCCCTCCTCCTCAGGTTCTCTATCGACGAGTCT
GGTAGCTGAGCGTTGGGCTGTAGGTCGCTGTGCTGTGTGATCCCCCAGAGCCATGCCCGAGATAGTGGATACCTGTTCGTTGGCCTCTCC
GGCTTCCGTCTGCCGGACCAAGCACCTGCACCTGCGCTGCAGCGTCGACTTTACTCGCCGGACGCTGACCGGGACTGCTGCTCTCACGGT
CCAGTCTCAGGAGGACAATCTGCGCAGCCTGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAA
ATATGCTCTTGGAGAAAGACAAAGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTAT
AGAAATTTCTTTTGAGACCTCTCCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTT
TAGTCAGTGCCAGGCCATCCACTGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGT
CCCTAAAGAACTGGTGGCACTTATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCAT
CCAAAAAGTTCCAATACCCTGCTACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTC
TGAGAAAGAGCAGGTGGAAAAGTCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGT
ATGGGGACAGTATGACCTATTGGTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCT
ACTGGCAGGCGACAAGTCACTCTCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGA
TCACTTTTGGTTAAATGAGGGACATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGC
TCTGGGAGGATGGGGAGAACTACAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATAT
AGACCCTGATGTAGCTTATTCTTCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGAT
TTTCCTAGGATTCTTAAAAGCTTATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTT
TAAAGATAAGGTTGATGTTCTCAATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATAT
GACTCTGACAAATGCTTGTATTGCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTC
TGGAATATATGATTGTGCCAAGAAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCAT
ACCTTATGCAGGCATAGATCTTGCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGT
CATGGTGTTGCTGGGATGCGGTGCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGC
TCAAGCCATGTTAGAAGGTTCCCCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAG
AGGCATCACCCCAAACTTCATGAAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAAC
CCAGAAATGATGTTGCATTTTTTGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAA
GTCTATGGCAAAAGAAGCTGCATTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACAC
AGAAATGTTCAAAATCATAGTTTTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCC
CTGAATCCGAAATCTGAAAATGTACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTT
TACGTTTATGCCAGTTCCTTTATATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACC
ATTAATAGAAAATCATTACATTTAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCT
GAATACGAATGAACACAGTGGTGGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTA
CCATTATTTGGTTCCTGGAGTTATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTT
TATCCTGCCATTGCTTTGAAAAGCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTT
TGTTTCCTACCTTTTGAATCAGATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCA
TGAAGTGGATTGATCATGAGCAAATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCAC
AAAGGTGAGAGATACATATTAATAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATA
TACATTCATATTCTCTCTTGCCCCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTT
ACTAAAGCCATTTTTATAGTCAACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTT
TTAATTTAGTTCTTAAACTCATTTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCAT
TTTCTTTATTTGAACCTACCTCTTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCA
TTTATATTAGTTATGTTTGATAAATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAG
TAATATATAAAGTGACAATATTAAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAA
CTTTGAAATTTCAAACTTCTGGAAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTAC
ATCTTGTATCTTTTCCAAAAAATGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTT
ACTTACAGTTTCTATCAAAAATATATATTTGTTTCTAAAATTACTTGTTTTCCAGTTTTTATTTTTTTTAGAGAAAATTCTTAAGTCTCA
GTTTCCTAATTGAAAAAAAAAAATTATAAATAAAGCAAAAATTGTATCCTACAGCTTAGCTAGCTTAGATGTTTGGCACCAGTTTGAATC
ATGCTTTTTACAGCTGGCTCCATGTAGTCTTTCCAAACATTTTGGCCTTTCCTGAGCAGCCCTTGTAGATATTGTCTGTATGATGCATTT
TGACACAAGGTGATATTTTTTGTGATATCAAAATTCCACATTTACCCATTAGAGTTACAGCCCTGGGGTTCACAGTACCAAGGGGGACCC
AGAGCCTCAGGATTGGCCAGGCTCATTTTGCCGTGGAGTATCAGTTTGTCTTGAAATTGTGGGAAAAAATTCTAAGTTGAATTCACTGGT
AAGTAATTTTTTAAAATTTCATAATGCAGATTACATCCAAAATTTGATTTAAAAATTAAAACATAAGACTGCAGAGAAATTCTGCATTTC
AACTCCAATACTATCCAGACTTCAGAAATAACTTATCAGTTATTTCTGTAAGCTTCTTGCTTACCTGGATACCTGACAGGTGAGATGGCT
GTAGCAGACACTGGCAGTTCCCTGCCCACACACCTGTCCCTGTCCACAGCTGCACAAGGCAGCTCTGTGTGCAATTGCCAGCATCTGCTC
CTCTGTTCTCAGGGAATCTTTGTTAGAAAAATGCTGCCATATTTGTTTCTCACCTATTAGTCTTGTCTCCCAGTCAAGAGAATAAATTTA

>50256_50256_6_LTA4H-SLC25A24_LTA4H_chr12_96402872_ENST00000228740_SLC25A24_chr1_108686332_ENST00000565488_length(amino acids)=645AA_BP=476
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEIS
LPIALSKNQEIVIEISFETSPKSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP
DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGG
MENPCLTFVTPTLLAGDKSLSNVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET
HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLY
SPGLPPIKPNYDMTLTNACIALSQRWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYW
LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISY

--------------------------------------------------------------
>50256_50256_7_LTA4H-SLC25A24_LTA4H_chr12_96402872_ENST00000552789_SLC25A24_chr1_108686332_ENST00000370041_length(transcript)=3798nt_BP=1464nt
ATGTTTGTCTTTTAAAGCAACAAGGGAAGAGGGCAAGAGGATGCATGGGCTTGGGAGTTTATTTTCTCTCCTCCTGTCTACACCTCCTCT
AATCTGTCTCCCATGCTGCCACAGAGAAATCTTTCTAAAAGACAAGTACCGACCATGCATATCCCAGTTAAGACTCGTCGACTTCTTGCA
GCCTTAAAGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAAATATGCTCTTGGAGAAAGACAA
AGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTATAGAAATTTCTTTTGAGACCTCT
CCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTTTAGTCAGTGCCAGGCCATCCAC
TGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGTCCCTAAAGAACTGGTGGCACTT
ATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCATCCAAAAAGTTCCAATACCCTGC
TACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTCTGAGAAAGAGCAGGTGGAAAAG
TCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGTATGGGGACAGTATGACCTATTG
GTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCTACTGGCAGGCGACAAGTCACTC
TCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAGGGA
CATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGCTCTGGGAGGATGGGGAGAACTA
CAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATATAGACCCTGATGTAGCTTATTCT
TCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGATTTTCCTAGGATTCTTAAAAGCT
TATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTTTAAAGATAAGGTTGATGTTCTC
AATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATATGACTCTGACAAATGCTTGTATT
GCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTCTGGAATATATGATTGTGCCAAG
AAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATAGATCTT
GCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGT
GCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAAGGTTCC
CCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAGAGGCATCACCCCAAACTTCATG
AAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAACCCAGAAATGATGTTGCATTTTT
TGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAAGTCTATGGCAAAAGAAGCTGCA
TTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACACAGAAATGTTCAAAATCATAGTT
TTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCCCTGAATCCGAAATCTGAAAATG
TACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTTTACGTTTATGCCAGTTCCTTTA
TATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACCATTAATAGAAAATCATTACATT
TAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCTGAATACGAATGAACACAGTGGT
GGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTACCATTATTTGGTTCCTGGAGTT
ATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTTTATCCTGCCATTGCTTTGAAAA
GCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTTTGTTTCCTACCTTTTGAATCAG
ATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCATGAAGTGGATTGATCATGAGCA
AATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCACAAAGGTGAGAGATACATATTAA
TAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATATACATTCATATTCTCTCTTGCC
CCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTTACTAAAGCCATTTTTATAGTCA
ACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTTTTAATTTAGTTCTTAAACTCAT
TTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCATTTTCTTTATTTGAACCTACCTC
TTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCATTTATATTAGTTATGTTTGATA
AATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAGTAATATATAAAGTGACAATATT
AAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAACTTTGAAATTTCAAACTTCTGG
AAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTACATCTTGTATCTTTTCCAAAAAA
TGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTTACTTACAGTTTCTATCAAAAAT

>50256_50256_7_LTA4H-SLC25A24_LTA4H_chr12_96402872_ENST00000552789_SLC25A24_chr1_108686332_ENST00000370041_length(amino acids)=624AA_BP=455
MSPMLPQRNLSKRQVPTMHIPVKTRRLLAALKVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSP
KSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCY
LIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLS
NVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSS
VPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIA
LSQRWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA

--------------------------------------------------------------
>50256_50256_8_LTA4H-SLC25A24_LTA4H_chr12_96402872_ENST00000552789_SLC25A24_chr1_108686332_ENST00000565488_length(transcript)=4585nt_BP=1464nt
ATGTTTGTCTTTTAAAGCAACAAGGGAAGAGGGCAAGAGGATGCATGGGCTTGGGAGTTTATTTTCTCTCCTCCTGTCTACACCTCCTCT
AATCTGTCTCCCATGCTGCCACAGAGAAATCTTTCTAAAAGACAAGTACCGACCATGCATATCCCAGTTAAGACTCGTCGACTTCTTGCA
GCCTTAAAGGTTTTGGATACAAAGGACCTTACAATAGAAAAAGTAGTGATCAATGGACAAGAAGTCAAATATGCTCTTGGAGAAAGACAA
AGTTACAAGGGATCGCCAATGGAAATCTCTCTTCCTATCGCTTTGAGCAAAAATCAAGAAATTGTTATAGAAATTTCTTTTGAGACCTCT
CCAAAATCTTCTGCTCTCCAGTGGCTCACTCCTGAACAGACTTCTGGGAAGGAACACCCATATCTCTTTAGTCAGTGCCAGGCCATCCAC
TGCAGAGCAATCCTTCCTTGTCAGGACACTCCTTCTGTGAAATTAACCTATACTGCAGAGGTGTCTGTCCCTAAAGAACTGGTGGCACTT
ATGAGTGCTATTCGTGATGGAGAAACACCTGACCCAGAAGACCCAAGCAGGAAAATATACAAATTCATCCAAAAAGTTCCAATACCCTGC
TACCTGATTGCTTTAGTTGTTGGAGCTTTAGAAAGCAGGCAAATTGGCCCAAGAACTTTGGTGTGGTCTGAGAAAGAGCAGGTGGAAAAG
TCTGCTTATGAGTTTTCTGAGACTGAATCTATGCTTAAAATAGCAGAAGATCTGGGAGGACCGTATGTATGGGGACAGTATGACCTATTG
GTCCTGCCACCATCCTTCCCTTATGGTGGCATGGAGAATCCTTGCCTTACTTTTGTAACTCCTACTCTACTGGCAGGCGACAAGTCACTC
TCCAATGTCATTGCACATGAAATATCTCATAGCTGGACAGGGAATCTAGTGACCAACAAAACTTGGGATCACTTTTGGTTAAATGAGGGA
CATACTGTGTACTTGGAACGCCACATTTGCGGACGATTGTTTGGTGAAAAGTTCAGACATTTTAATGCTCTGGGAGGATGGGGAGAACTA
CAGAATTCGGTAAAGACATTTGGGGAGACACATCCTTTCACCAAACTTGTGGTTGATCTGACAGATATAGACCCTGATGTAGCTTATTCT
TCAGTTCCCTATGAGAAGGGCTTTGCTTTACTTTTTTACCTTGAACAACTGCTTGGAGGACCAGAGATTTTCCTAGGATTCTTAAAAGCT
TATGTTGAGAAGTTTTCCTATAAGAGCATAACTACTGATGACTGGAAGGATTTCCTGTATTCCTATTTTAAAGATAAGGTTGATGTTCTC
AATCAAGTTGATTGGAATGCCTGGCTCTACTCTCCTGGACTGCCTCCCATAAAGCCCAATTATGATATGACTCTGACAAATGCTTGTATT
GCCTTAAGTCAAAGATGGATTACTGTTATGAAAACCAGGCTGGCTGTAGGCAAAACTGGGCAGTACTCTGGAATATATGATTGTGCCAAG
AAGATTTTGAAACATGAAGGCTTGGGAGCTTTTTACAAAGGCTATGTTCCCAATTTATTAGGTATCATACCTTATGCAGGCATAGATCTT
GCTGTGTATGAGCTCTTGAAGTCCTATTGGCTGGATAATTTTGCAAAAGATTCTGTAAACCCTGGAGTCATGGTGTTGCTGGGATGCGGT
GCCTTATCCAGCACCTGTGGTCAGCTGGCCAGCTACCCATTGGCTTTGGTGAGAACTCGCATGCAGGCTCAAGCCATGTTAGAAGGTTCC
CCACAGCTGAATATGGTTGGCCTCTTTCGACGAATTATTTCCAAAGAAGGAATACCAGGACTTTACAGAGGCATCACCCCAAACTTCATG
AAGGTGCTCCCTGCTGTAGGCATCAGTTATGTGGTTTATGAAAATATGAAGCAAACTTTAGGAGTAACCCAGAAATGATGTTGCATTTTT
TGCTTTAGCCTGATAATTGAAACTTTCAACAATCTCTGGAGTGACTTTTTCTCCTCGAATTGAAACAAGTCTATGGCAAAAGAAGCTGCA
TTTTTTTCACAAAAGGGAAGATGGTAACAATGGTCACTTCAAACTTTTGGGCTAAATTATATGTACACAGAAATGTTCAAAATCATAGTT
TTAATGTGTTTTGAAAAGGCCACACAATTATACTTTATCTTTTCTTAATAATCCTGCAAATCTCTGCCCTGAATCCGAAATCTGAAAATG
TACTGGCTTGAACAAAATTTGTTTTGTGTGTTAGAGTTATAAATCATTAATCTTTATTTCGGGTGGTTTACGTTTATGCCAGTTCCTTTA
TATTTAAATTTCTTGTTTTATATATTTTGAATGTCTTTATAGATTTCTTTAAATTTCCTTATAGAACCATTAATAGAAAATCATTACATT
TAAAATATACCTTACAGCAAAAGCATCCAAATAAGTATAGGGTTTATGTCCTTATTTTTCTTTCAGCTGAATACGAATGAACACAGTGGT
GGAATTTCTGAAGGGAAGTGATGAAATTATATTTATTTCAGTGGGCACTTTTCCATTTTACCACTGTACCATTATTTGGTTCCTGGAGTT
ATACACTAATTTTCAGTATATTACTGTTAAATTACCAACACAAGGCAATTTATTTGAAAGATTCCGTTTATCCTGCCATTGCTTTGAAAA
GCAGCAGGAAACGAAATCCTTTGACTTGTATCAGCTTCTGCAGAGCATCTTTGTTTTCCTTTGTCCTTTGTTTCCTACCTTTTGAATCAG
ATTCCGTTTTAGTCAGGAAGACTTCTTGGGACCATTCTTAGTAACCTGAAATTTCTTTTTTAATTGCATGAAGTGGATTGATCATGAGCA
AATGATGTGCTTATTTCTCCCTCACTGTTGAATATCTTTGAACTTGCTGTTTTCAATATGGGCAGCACAAAGGTGAGAGATACATATTAA
TAGTAGTATGTATTACTCTTATACATTAGATACCTATATTTAAATGAAAGGCCCAATTTGTAAACATATACATTCATATTCTCTCTTGCC
CCAAGTTTTAGGAACATGTTAGGATATAGGAGACTTAATTTATAATAATGAGAGCATTTTTTTATTTTACTAAAGCCATTTTTATAGTCA
ACTATCTTTTCTTATTTGTGTGATTAGAACTTAGAAAAATATTTACTAGTTGAAGTTATTATCAGTTTTTAATTTAGTTCTTAAACTCAT
TTCACTTCTAATAATTTCTGTTATAAATTTCCAGCATTTTAATGAAAATCTAATGATGTAATAGGCATTTTCTTTATTTGAACCTACCTC
TTTTATTTTCTGAACCAAAGAGAAAGATGGACTGGTGTTTGTGAAACATTTTTAAAAATGTAGTTTCATTTATATTAGTTATGTTTGATA
AATGTCTCAGTATTTTTATAATATGATAAGCCTGGGATTCTACTTTTAGGGTTATTTGTACTTTTGAGTAATATATAAAGTGACAATATT
AAGGTACATGATCAGCTCTTTCTATTTTTACTCGTAAAAATTATGGAAATGAATAATTTTGCTAACAACTTTGAAATTTCAAACTTCTGG
AAAATATGAAAATATTCATTGTTCATTATGAATTTAAATTGTAAGGTATGAATGTGATTTGTCTGTACATCTTGTATCTTTTCCAAAAAA
TGATTCTGTATCTTTTGGAAAAAAGCCGAGAGTTGAAGATAGTATATTTCTGGTAGTACTGAATATTTACTTACAGTTTCTATCAAAAAT
ATATATTTGTTTCTAAAATTACTTGTTTTCCAGTTTTTATTTTTTTTAGAGAAAATTCTTAAGTCTCAGTTTCCTAATTGAAAAAAAAAA
ATTATAAATAAAGCAAAAATTGTATCCTACAGCTTAGCTAGCTTAGATGTTTGGCACCAGTTTGAATCATGCTTTTTACAGCTGGCTCCA
TGTAGTCTTTCCAAACATTTTGGCCTTTCCTGAGCAGCCCTTGTAGATATTGTCTGTATGATGCATTTTGACACAAGGTGATATTTTTTG
TGATATCAAAATTCCACATTTACCCATTAGAGTTACAGCCCTGGGGTTCACAGTACCAAGGGGGACCCAGAGCCTCAGGATTGGCCAGGC
TCATTTTGCCGTGGAGTATCAGTTTGTCTTGAAATTGTGGGAAAAAATTCTAAGTTGAATTCACTGGTAAGTAATTTTTTAAAATTTCAT
AATGCAGATTACATCCAAAATTTGATTTAAAAATTAAAACATAAGACTGCAGAGAAATTCTGCATTTCAACTCCAATACTATCCAGACTT
CAGAAATAACTTATCAGTTATTTCTGTAAGCTTCTTGCTTACCTGGATACCTGACAGGTGAGATGGCTGTAGCAGACACTGGCAGTTCCC
TGCCCACACACCTGTCCCTGTCCACAGCTGCACAAGGCAGCTCTGTGTGCAATTGCCAGCATCTGCTCCTCTGTTCTCAGGGAATCTTTG

>50256_50256_8_LTA4H-SLC25A24_LTA4H_chr12_96402872_ENST00000552789_SLC25A24_chr1_108686332_ENST00000565488_length(amino acids)=624AA_BP=455
MSPMLPQRNLSKRQVPTMHIPVKTRRLLAALKVLDTKDLTIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSP
KSSALQWLTPEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETPDPEDPSRKIYKFIQKVPIPCY
LIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETESMLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLS
NVIAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGETHPFTKLVVDLTDIDPDVAYSS
VPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSITTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIA
LSQRWITVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for LTA4H-SLC25A24


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LTA4H-SLC25A24


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LTA4H-SLC25A24


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource