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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LTBP4-RBM39 (FusionGDB2 ID:50297)

Fusion Gene Summary for LTBP4-RBM39

check button Fusion gene summary
Fusion gene informationFusion gene name: LTBP4-RBM39
Fusion gene ID: 50297
HgeneTgene
Gene symbol

LTBP4

RBM39

Gene ID

8425

9584

Gene namelatent transforming growth factor beta binding protein 4RNA binding motif protein 39
SynonymsARCL1C|LTBP-4|LTBP4L|LTBP4SCAPER|CAPERalpha|FSAP59|HCC1|RNPC2
Cytomap

19q13.2

20q11.22

Type of geneprotein-codingprotein-coding
Descriptionlatent-transforming growth factor beta-binding protein 4latent transforming growth factor-beta binding protein 4LRNA-binding protein 39CAPER alphaRNA-binding region (RNP1, RRM) containing 2coactivator of activating protein-1 and estrogen receptorsepididymis secretory sperm binding proteinfunctional spliceosome-associated protein 59hepatocellular carcinoma prot
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000602240, ENST00000204005, 
ENST00000308370, ENST00000396819, 
ENST00000545697, ENST00000243562, 
ENST00000253363, ENST00000361162, 
ENST00000407261, ENST00000528062, 
ENST00000397370, ENST00000463098, 
Fusion gene scores* DoF score8 X 10 X 7=56024 X 16 X 12=4608
# samples 1027
** MAII scorelog2(10/560*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(27/4608*10)=-4.09310940439148
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LTBP4 [Title/Abstract] AND RBM39 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLTBP4(41114509)-RBM39(34301018), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneLTBP4

GO:0030162

regulation of proteolysis

9660815


check buttonFusion gene breakpoints across LTBP4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RBM39 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1544LTBP4chr19

41114509

+RBM39chr20

34301018

-


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Fusion Gene ORF analysis for LTBP4-RBM39

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000602240ENST00000253363LTBP4chr19

41114509

+RBM39chr20

34301018

-
3UTR-3CDSENST00000602240ENST00000361162LTBP4chr19

41114509

+RBM39chr20

34301018

-
3UTR-3CDSENST00000602240ENST00000407261LTBP4chr19

41114509

+RBM39chr20

34301018

-
3UTR-3CDSENST00000602240ENST00000528062LTBP4chr19

41114509

+RBM39chr20

34301018

-
3UTR-intronENST00000602240ENST00000397370LTBP4chr19

41114509

+RBM39chr20

34301018

-
3UTR-intronENST00000602240ENST00000463098LTBP4chr19

41114509

+RBM39chr20

34301018

-
5CDS-intronENST00000204005ENST00000397370LTBP4chr19

41114509

+RBM39chr20

34301018

-
5CDS-intronENST00000204005ENST00000463098LTBP4chr19

41114509

+RBM39chr20

34301018

-
5CDS-intronENST00000308370ENST00000397370LTBP4chr19

41114509

+RBM39chr20

34301018

-
5CDS-intronENST00000308370ENST00000463098LTBP4chr19

41114509

+RBM39chr20

34301018

-
5CDS-intronENST00000396819ENST00000397370LTBP4chr19

41114509

+RBM39chr20

34301018

-
5CDS-intronENST00000396819ENST00000463098LTBP4chr19

41114509

+RBM39chr20

34301018

-
5UTR-3CDSENST00000545697ENST00000253363LTBP4chr19

41114509

+RBM39chr20

34301018

-
5UTR-3CDSENST00000545697ENST00000361162LTBP4chr19

41114509

+RBM39chr20

34301018

-
5UTR-3CDSENST00000545697ENST00000407261LTBP4chr19

41114509

+RBM39chr20

34301018

-
5UTR-3CDSENST00000545697ENST00000528062LTBP4chr19

41114509

+RBM39chr20

34301018

-
5UTR-intronENST00000545697ENST00000397370LTBP4chr19

41114509

+RBM39chr20

34301018

-
5UTR-intronENST00000545697ENST00000463098LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000204005ENST00000253363LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000204005ENST00000361162LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000204005ENST00000407261LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000204005ENST00000528062LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000308370ENST00000253363LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000308370ENST00000361162LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000308370ENST00000407261LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000308370ENST00000528062LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000396819ENST00000253363LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000396819ENST00000361162LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000396819ENST00000407261LTBP4chr19

41114509

+RBM39chr20

34301018

-
In-frameENST00000396819ENST00000528062LTBP4chr19

41114509

+RBM39chr20

34301018

-
intron-3CDSENST00000243562ENST00000253363LTBP4chr19

41114509

+RBM39chr20

34301018

-
intron-3CDSENST00000243562ENST00000361162LTBP4chr19

41114509

+RBM39chr20

34301018

-
intron-3CDSENST00000243562ENST00000407261LTBP4chr19

41114509

+RBM39chr20

34301018

-
intron-3CDSENST00000243562ENST00000528062LTBP4chr19

41114509

+RBM39chr20

34301018

-
intron-intronENST00000243562ENST00000397370LTBP4chr19

41114509

+RBM39chr20

34301018

-
intron-intronENST00000243562ENST00000463098LTBP4chr19

41114509

+RBM39chr20

34301018

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000204005LTBP4chr1941114509+ENST00000253363RBM39chr2034301018-2884151602012670
ENST00000204005LTBP4chr1941114509+ENST00000361162RBM39chr2034301018-2866151601994664
ENST00000204005LTBP4chr1941114509+ENST00000528062RBM39chr2034301018-2596151602012670
ENST00000204005LTBP4chr1941114509+ENST00000407261RBM39chr2034301018-2166151602012670
ENST00000308370LTBP4chr1941114509+ENST00000253363RBM39chr2034301018-2995162702123707
ENST00000308370LTBP4chr1941114509+ENST00000361162RBM39chr2034301018-2977162702105701
ENST00000308370LTBP4chr1941114509+ENST00000528062RBM39chr2034301018-2707162702123707
ENST00000308370LTBP4chr1941114509+ENST00000407261RBM39chr2034301018-2277162702123707
ENST00000396819LTBP4chr1941114509+ENST00000253363RBM39chr2034301018-28111443171939640
ENST00000396819LTBP4chr1941114509+ENST00000361162RBM39chr2034301018-27931443171921634
ENST00000396819LTBP4chr1941114509+ENST00000528062RBM39chr2034301018-25231443171939640
ENST00000396819LTBP4chr1941114509+ENST00000407261RBM39chr2034301018-20931443171939640

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000204005ENST00000253363LTBP4chr1941114509+RBM39chr2034301018-0.0114131030.98858696
ENST00000204005ENST00000361162LTBP4chr1941114509+RBM39chr2034301018-0.0123447370.9876552
ENST00000204005ENST00000528062LTBP4chr1941114509+RBM39chr2034301018-0.0144123440.9855877
ENST00000204005ENST00000407261LTBP4chr1941114509+RBM39chr2034301018-0.0297810270.97021896
ENST00000308370ENST00000253363LTBP4chr1941114509+RBM39chr2034301018-0.0154102340.98458976
ENST00000308370ENST00000361162LTBP4chr1941114509+RBM39chr2034301018-0.0178597590.98214024
ENST00000308370ENST00000528062LTBP4chr1941114509+RBM39chr2034301018-0.0197543040.98024565
ENST00000308370ENST00000407261LTBP4chr1941114509+RBM39chr2034301018-0.0390850980.96091485
ENST00000396819ENST00000253363LTBP4chr1941114509+RBM39chr2034301018-0.010710550.98928946
ENST00000396819ENST00000361162LTBP4chr1941114509+RBM39chr2034301018-0.0137379520.986262
ENST00000396819ENST00000528062LTBP4chr1941114509+RBM39chr2034301018-0.0132105650.9867894
ENST00000396819ENST00000407261LTBP4chr1941114509+RBM39chr2034301018-0.0273897960.9726102

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Fusion Genomic Features for LTBP4-RBM39


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for LTBP4-RBM39


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:41114509/chr20:34301018)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234149_1815421624.0DomainEGF-like 1
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234287_3395421624.0DomainTB 1
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234357_3975421624.0DomainEGF-like 2%3B calcium-binding
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234407_4595421624.0DomainTB 2
TgeneRBM39chr19:41114509chr20:34301018ENST000002533631017409_416365531.0Compositional biasNote=Poly-Ala
TgeneRBM39chr19:41114509chr20:34301018ENST000003611621017409_416365525.0Compositional biasNote=Poly-Ala
TgeneRBM39chr19:41114509chr20:34301018ENST00000528062916409_416343509.0Compositional biasNote=Poly-Ala
TgeneRBM39chr19:41114509chr20:34301018ENST000002533631017445_508365531.0DomainRRM 3
TgeneRBM39chr19:41114509chr20:34301018ENST000003611621017445_508365525.0DomainRRM 3
TgeneRBM39chr19:41114509chr20:34301018ENST00000528062916445_508343509.0DomainRRM 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+12341119_11755421624.0Compositional biasNote=Pro-rich
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+12341407_14925421624.0Compositional biasNote=Pro-rich
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234478_5655421624.0Compositional biasNote=Pro-rich
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234549_11185421624.0Compositional biasNote=Cys-rich
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+12341049_10905421624.0DomainEGF-like 12%3B calcium-binding
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+12341181_12355421624.0DomainTB 3
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+12341253_12955421624.0DomainEGF-like 13%3B calcium-binding
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+12341296_13375421624.0DomainEGF-like 14%3B calcium-binding
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+12341349_14025421624.0DomainTB 4
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+12341533_15735421624.0DomainEGF-like 15
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+12341574_16185421624.0DomainEGF-like 16
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234545_5865421624.0DomainEGF-like 3
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234587_6285421624.0DomainEGF-like 4%3B calcium-binding
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234629_6705421624.0DomainEGF-like 5%3B calcium-binding
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234671_7085421624.0DomainEGF-like 6%3B calcium-binding
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234710_7515421624.0DomainEGF-like 7%3B calcium-binding
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234752_7935421624.0DomainEGF-like 8%3B calcium-binding
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234834_8775421624.0DomainEGF-like 9%3B calcium-binding
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234878_9195421624.0DomainEGF-like 10%3B calcium-binding
HgeneLTBP4chr19:41114509chr20:34301018ENST00000308370+1234920_9605421624.0DomainEGF-like 11%3B calcium-binding
TgeneRBM39chr19:41114509chr20:34301018ENST00000253363101741_90365531.0Compositional biasNote=Arg/Ser-rich (RS domain)
TgeneRBM39chr19:41114509chr20:34301018ENST00000361162101741_90365525.0Compositional biasNote=Arg/Ser-rich (RS domain)
TgeneRBM39chr19:41114509chr20:34301018ENST0000052806291641_90343509.0Compositional biasNote=Arg/Ser-rich (RS domain)
TgeneRBM39chr19:41114509chr20:34301018ENST000002533631017153_230365531.0DomainRRM 1
TgeneRBM39chr19:41114509chr20:34301018ENST000002533631017250_328365531.0DomainRRM 2
TgeneRBM39chr19:41114509chr20:34301018ENST000003611621017153_230365525.0DomainRRM 1
TgeneRBM39chr19:41114509chr20:34301018ENST000003611621017250_328365525.0DomainRRM 2
TgeneRBM39chr19:41114509chr20:34301018ENST00000528062916153_230343509.0DomainRRM 1
TgeneRBM39chr19:41114509chr20:34301018ENST00000528062916250_328343509.0DomainRRM 2
TgeneRBM39chr19:41114509chr20:34301018ENST000002533631017291_355365531.0RegionActivating domain
TgeneRBM39chr19:41114509chr20:34301018ENST000003611621017291_355365525.0RegionActivating domain
TgeneRBM39chr19:41114509chr20:34301018ENST00000528062916291_355343509.0RegionActivating domain


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Fusion Gene Sequence for LTBP4-RBM39


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>50297_50297_1_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000204005_RBM39_chr20_34301018_ENST00000253363_length(transcript)=2884nt_BP=1516nt
ATGGGAGACGTAAAAGCGTTGCTGTTTGTCGCTGCTGCCCGGGCCAGACGTCTAGGAGGAGCCGCTGCATCCGAGTCCCTGGCTGTCTCC
GAAGCCTTCTGCAGGGTCCGAAGCTGCCAGCCCAAAAAGTGTGCAGGCCCCCAGCGGTGCCTGAACCCAGTGCCTGCAGTGCCCAGTCCC
AGCCCCAGCGTGAGGAAGAGACAGGTGTCCCTCAACTGGCAGCCACTGACGCTCCAGGAGGCCAGAGCTCTACTGAAGCGGCGGCGGCCC
CGGGGGCCAGGGGGCCGGGGACTACTGAGAAGGAGGCCCCCACAGCGTGCCCCCGCTGGCAAGGCCCCGGTCCTGTGTCCCTTGATCTGT
CACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGCCAGTTGCACTCCTCGGGCGCC
CGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGCGACGACGAGCACGGCGTGGCA
TCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTGTCTGGCCCTTGGGAGGAGGCG
GACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTGGCACAGAGCGCGCCGCGGGAG
GACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCCCCGCTGCCCGGGCTCCGGACG
CAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGCCTGGGGAACTCCGAAAGAGTG
AGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAGTGCGCGACTGGCGGGCGCTGC
CAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGACTCGTCCCGCAGCAGCTGCATC
TCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTGCCCATTCTGCGGAACATCACT
AAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTCGGCTCAGAGGGTTTCCGGGAG
ATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGCCAGGAGCCACCCCGAGTGTCA
CTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTGGAGCCCCGGCCTGAACCCCGG
CCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCTGAATCAGGTACAGGTTTGCAG
ATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGAATTCTCTTTTGTTATAGATTTGCAA
ACAAGACTTTCCCAGCAGACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACACAATGTTTCCAACTCTCTAAC
ATGTTTAACCCTCAAACAGAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAATGTAATAAACATGGAGGAGTT
ATTCATATTTATGTTGACAAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCAGCTATTGCTGCTGTCAATGCA
TTGCATGGCAGGTGGTTTGCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAACCTGTTTCCTGATTCTATGACA
GCAACACAGCTACTGGTTCCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTTCTTTCTTGAGAATTCATCTTG
AGTTATCTTTTATTTAGATAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTACCTTGAAAAAATAAAAATGTT
AACAGGAATGCAGTGTGCTCATTCTCCCTAAATAGTAAATCCCACTGTATACAAAACTGTTCTCTTGTTCTGCCTTTTAAAATGTTCATG
TAGAAAATTAATGAACTATAGGAATAGCTCTAGGAGAACAAATGTGCTTTCTGTAAAAAGGCAGACCAGGGATGTAATGTTTTTAATGTT
TCAGAAGCCTAACTTTTTACACAGTGGTTACATTTCACATTTCACTAATGTTGATATTTGGCTGATGGTTGAGCAGTTTCTGAAATACAC
ATTTAGTGTATGGAAATACAAGACAGCTAAAGGGCTGTTTGGTTAGCATCTCATCTTGCATTCTGATCAATTGGCAAGAAAGGGAGATTT
CAAAATTATATTTCTTGATGGTATCTTTTCAATTAATGTATCTGTAAAAGTTTCTTTGTAAATACTATGTGTTCTGGTGTGTCTTAAAAT
TCCAAACAAAATGATCCCTGCATTTCCTGAAGATGTTTAAACGTGAGAGTCTGGTAGGCAAAGCAGTCTGAGAAAGAAATAGGAAATGCA
GAAATAGGTTTTGTCTGGTTGCATATAATCTTTGCTCTTTTTAAGCTCTGTGAGCTCTGAAATATATTTTTGGGTTACTTCAGTGTGTTT
GACAAGACAGCTTGATATTTCTATCAAACAAATGACTTTCATATTGCAACAATCTTTGTAAGAACCACTCAAATAAAAGTCTCTTAAAAA

>50297_50297_1_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000204005_RBM39_chr20_34301018_ENST00000253363_length(amino acids)=670AA_BP=505
MGDVKALLFVAAARARRLGGAAASESLAVSEAFCRVRSCQPKKCAGPQRCLNPVPAVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRP
RGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVA
SMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRT
QEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI
SQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVS
LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQ
TRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNA

--------------------------------------------------------------
>50297_50297_2_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000204005_RBM39_chr20_34301018_ENST00000361162_length(transcript)=2866nt_BP=1516nt
ATGGGAGACGTAAAAGCGTTGCTGTTTGTCGCTGCTGCCCGGGCCAGACGTCTAGGAGGAGCCGCTGCATCCGAGTCCCTGGCTGTCTCC
GAAGCCTTCTGCAGGGTCCGAAGCTGCCAGCCCAAAAAGTGTGCAGGCCCCCAGCGGTGCCTGAACCCAGTGCCTGCAGTGCCCAGTCCC
AGCCCCAGCGTGAGGAAGAGACAGGTGTCCCTCAACTGGCAGCCACTGACGCTCCAGGAGGCCAGAGCTCTACTGAAGCGGCGGCGGCCC
CGGGGGCCAGGGGGCCGGGGACTACTGAGAAGGAGGCCCCCACAGCGTGCCCCCGCTGGCAAGGCCCCGGTCCTGTGTCCCTTGATCTGT
CACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGCCAGTTGCACTCCTCGGGCGCC
CGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGCGACGACGAGCACGGCGTGGCA
TCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTGTCTGGCCCTTGGGAGGAGGCG
GACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTGGCACAGAGCGCGCCGCGGGAG
GACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCCCCGCTGCCCGGGCTCCGGACG
CAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGCCTGGGGAACTCCGAAAGAGTG
AGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAGTGCGCGACTGGCGGGCGCTGC
CAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGACTCGTCCCGCAGCAGCTGCATC
TCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTGCCCATTCTGCGGAACATCACT
AAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTCGGCTCAGAGGGTTTCCGGGAG
ATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGCCAGGAGCCACCCCGAGTGTCA
CTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTGGAGCCCCGGCCTGAACCCCGG
CCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCTGAATCAGGTACAGGTTTGCAG
ATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGATTTGCAAACAAGACTTTCCCAGCAG
ACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACACAATGTTTCCAACTCTCTAACATGTTTAACCCTCAAACA
GAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAATGTAATAAACATGGAGGAGTTATTCATATTTATGTTGAC
AAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCAGCTATTGCTGCTGTCAATGCATTGCATGGCAGGTGGTTT
GCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAACCTGTTTCCTGATTCTATGACAGCAACACAGCTACTGGTT
CCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTTCTTTCTTGAGAATTCATCTTGAGTTATCTTTTATTTAGA
TAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTACCTTGAAAAAATAAAAATGTTAACAGGAATGCAGTGTGC
TCATTCTCCCTAAATAGTAAATCCCACTGTATACAAAACTGTTCTCTTGTTCTGCCTTTTAAAATGTTCATGTAGAAAATTAATGAACTA
TAGGAATAGCTCTAGGAGAACAAATGTGCTTTCTGTAAAAAGGCAGACCAGGGATGTAATGTTTTTAATGTTTCAGAAGCCTAACTTTTT
ACACAGTGGTTACATTTCACATTTCACTAATGTTGATATTTGGCTGATGGTTGAGCAGTTTCTGAAATACACATTTAGTGTATGGAAATA
CAAGACAGCTAAAGGGCTGTTTGGTTAGCATCTCATCTTGCATTCTGATCAATTGGCAAGAAAGGGAGATTTCAAAATTATATTTCTTGA
TGGTATCTTTTCAATTAATGTATCTGTAAAAGTTTCTTTGTAAATACTATGTGTTCTGGTGTGTCTTAAAATTCCAAACAAAATGATCCC
TGCATTTCCTGAAGATGTTTAAACGTGAGAGTCTGGTAGGCAAAGCAGTCTGAGAAAGAAATAGGAAATGCAGAAATAGGTTTTGTCTGG
TTGCATATAATCTTTGCTCTTTTTAAGCTCTGTGAGCTCTGAAATATATTTTTGGGTTACTTCAGTGTGTTTGACAAGACAGCTTGATAT

>50297_50297_2_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000204005_RBM39_chr20_34301018_ENST00000361162_length(amino acids)=664AA_BP=505
MGDVKALLFVAAARARRLGGAAASESLAVSEAFCRVRSCQPKKCAGPQRCLNPVPAVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRP
RGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVA
SMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRT
QEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI
SQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVS
LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQ
TEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWF

--------------------------------------------------------------
>50297_50297_3_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000204005_RBM39_chr20_34301018_ENST00000407261_length(transcript)=2166nt_BP=1516nt
ATGGGAGACGTAAAAGCGTTGCTGTTTGTCGCTGCTGCCCGGGCCAGACGTCTAGGAGGAGCCGCTGCATCCGAGTCCCTGGCTGTCTCC
GAAGCCTTCTGCAGGGTCCGAAGCTGCCAGCCCAAAAAGTGTGCAGGCCCCCAGCGGTGCCTGAACCCAGTGCCTGCAGTGCCCAGTCCC
AGCCCCAGCGTGAGGAAGAGACAGGTGTCCCTCAACTGGCAGCCACTGACGCTCCAGGAGGCCAGAGCTCTACTGAAGCGGCGGCGGCCC
CGGGGGCCAGGGGGCCGGGGACTACTGAGAAGGAGGCCCCCACAGCGTGCCCCCGCTGGCAAGGCCCCGGTCCTGTGTCCCTTGATCTGT
CACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGCCAGTTGCACTCCTCGGGCGCC
CGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGCGACGACGAGCACGGCGTGGCA
TCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTGTCTGGCCCTTGGGAGGAGGCG
GACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTGGCACAGAGCGCGCCGCGGGAG
GACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCCCCGCTGCCCGGGCTCCGGACG
CAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGCCTGGGGAACTCCGAAAGAGTG
AGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAGTGCGCGACTGGCGGGCGCTGC
CAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGACTCGTCCCGCAGCAGCTGCATC
TCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTGCCCATTCTGCGGAACATCACT
AAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTCGGCTCAGAGGGTTTCCGGGAG
ATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGCCAGGAGCCACCCCGAGTGTCA
CTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTGGAGCCCCGGCCTGAACCCCGG
CCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCTGAATCAGGTACAGGTTTGCAG
ATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGAATTCTCTTTTGTTATAGATTTGCAA
ACAAGACTTTCCCAGCAGACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACACAATGTTTCCAACTCTCTAAC
ATGTTTAACCCTCAAACAGAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAATGTAATAAACATGGAGGAGTT
ATTCATATTTATGTTGACAAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCAGCTATTGCTGCTGTCAATGCA
TTGCATGGCAGGTGGTTTGCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAACCTGTTTCCTGATTCTATGACA
GCAACACAGCTACTGGTTCCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTTCTTTCTTGAGAATTCATCTTG
AGTTATCTTTTATTTAGATAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTACCTTGAAAAAATAAAAATGTT

>50297_50297_3_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000204005_RBM39_chr20_34301018_ENST00000407261_length(amino acids)=670AA_BP=505
MGDVKALLFVAAARARRLGGAAASESLAVSEAFCRVRSCQPKKCAGPQRCLNPVPAVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRP
RGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVA
SMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRT
QEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI
SQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVS
LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQ
TRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNA

--------------------------------------------------------------
>50297_50297_4_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000204005_RBM39_chr20_34301018_ENST00000528062_length(transcript)=2596nt_BP=1516nt
ATGGGAGACGTAAAAGCGTTGCTGTTTGTCGCTGCTGCCCGGGCCAGACGTCTAGGAGGAGCCGCTGCATCCGAGTCCCTGGCTGTCTCC
GAAGCCTTCTGCAGGGTCCGAAGCTGCCAGCCCAAAAAGTGTGCAGGCCCCCAGCGGTGCCTGAACCCAGTGCCTGCAGTGCCCAGTCCC
AGCCCCAGCGTGAGGAAGAGACAGGTGTCCCTCAACTGGCAGCCACTGACGCTCCAGGAGGCCAGAGCTCTACTGAAGCGGCGGCGGCCC
CGGGGGCCAGGGGGCCGGGGACTACTGAGAAGGAGGCCCCCACAGCGTGCCCCCGCTGGCAAGGCCCCGGTCCTGTGTCCCTTGATCTGT
CACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGCCAGTTGCACTCCTCGGGCGCC
CGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGCGACGACGAGCACGGCGTGGCA
TCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTGTCTGGCCCTTGGGAGGAGGCG
GACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTGGCACAGAGCGCGCCGCGGGAG
GACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCCCCGCTGCCCGGGCTCCGGACG
CAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGCCTGGGGAACTCCGAAAGAGTG
AGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAGTGCGCGACTGGCGGGCGCTGC
CAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGACTCGTCCCGCAGCAGCTGCATC
TCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTGCCCATTCTGCGGAACATCACT
AAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTCGGCTCAGAGGGTTTCCGGGAG
ATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGCCAGGAGCCACCCCGAGTGTCA
CTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTGGAGCCCCGGCCTGAACCCCGG
CCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCTGAATCAGGTACAGGTTTGCAG
ATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGAATTCTCTTTTGTTATAGATTTGCAA
ACAAGACTTTCCCAGCAGACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACACAATGTTTCCAACTCTCTAAC
ATGTTTAACCCTCAAACAGAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAATGTAATAAACATGGAGGAGTT
ATTCATATTTATGTTGACAAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCAGCTATTGCTGCTGTCAATGCA
TTGCATGGCAGGTGGTTTGCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAACCTGTTTCCTGATTCTATGACA
GCAACACAGCTACTGGTTCCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTTCTTTCTTGAGAATTCATCTTG
AGTTATCTTTTATTTAGATAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTACCTTGAAAAAATAAAAATGTT
AACAGGAATGCAGTGTGCTCATTCTCCCTAAATAGTAAATCCCACTGTATACAAAACTGTTCTCTTGTTCTGCCTTTTAAAATGTTCATG
TAGAAAATTAATGAACTATAGGAATAGCTCTAGGAGAACAAATGTGCTTTCTGTAAAAAGGCAGACCAGGGATGTAATGTTTTTAATGTT
TCAGAAGCCTAACTTTTTACACAGTGGTTACATTTCACATTTCACTAATGTTGATATTTGGCTGATGGTTGAGCAGTTTCTGAAATACAC
ATTTAGTGTATGGAAATACAAGACAGCTAAAGGGCTGTTTGGTTAGCATCTCATCTTGCATTCTGATCAATTGGCAAGAAAGGGAGATTT

>50297_50297_4_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000204005_RBM39_chr20_34301018_ENST00000528062_length(amino acids)=670AA_BP=505
MGDVKALLFVAAARARRLGGAAASESLAVSEAFCRVRSCQPKKCAGPQRCLNPVPAVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRP
RGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVA
SMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRT
QEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI
SQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVS
LSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQ
TRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNA

--------------------------------------------------------------
>50297_50297_5_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000308370_RBM39_chr20_34301018_ENST00000253363_length(transcript)=2995nt_BP=1627nt
ATGCCGAGGCCTGGCACCAGCGGCCGCCGCCCCCTCCTGCTGGTGCTGTTGCTGCCGCTCTTCGCAGCCGCCACCTCCGCCGCCAGCCCC
AGCCCCAGCCCCAGCCAGGTCGTCGAGGTCCCGGGGGTCCCCAGCCGCCCGGCCAGCGTTGCTGTTTGTCGCTGCTGCCCGGGCCAGACG
TCTAGGAGGAGCCGCTGCATCCGAGCCTTCTGCAGGGTCCGAAGCTGCCAGCCCAAAAAGTGTGCAGGCCCCCAGCGGTGCCTGAACCCA
GTGCCTGCAGTGCCCAGTCCCAGCCCCAGCGTGAGGAAGAGACAGGTGTCCCTCAACTGGCAGCCACTGACGCTCCAGGAGGCCAGAGCT
CTACTGAAGCGGCGGCGGCCCCGGGGGCCAGGGGGCCGGGGACTACTGAGAAGGAGGCCCCCACAGCGTGCCCCCGCTGGCAAGGCCCCG
GTCCTGTGTCCCTTGATCTGTCACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGC
CAGTTGCACTCCTCGGGCGCCCGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGC
GACGACGAGCACGGCGTGGCATCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTG
TCTGGCCCTTGGGAGGAGGCGGACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTG
GCACAGAGCGCGCCGCGGGAGGACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCC
CCGCTGCCCGGGCTCCGGACGCAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGC
CTGGGGAACTCCGAAAGAGTGAGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAG
TGCGCGACTGGCGGGCGCTGCCAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGAC
TCGTCCCGCAGCAGCTGCATCTCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTG
CCCATTCTGCGGAACATCACTAAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTC
GGCTCAGAGGGTTTCCGGGAGATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGC
CAGGAGCCACCCCGAGTGTCACTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTG
GAGCCCCGGCCTGAACCCCGGCCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCT
GAATCAGGTACAGGTTTGCAGATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGAATTC
TCTTTTGTTATAGATTTGCAAACAAGACTTTCCCAGCAGACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACA
CAATGTTTCCAACTCTCTAACATGTTTAACCCTCAAACAGAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAA
TGTAATAAACATGGAGGAGTTATTCATATTTATGTTGACAAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCA
GCTATTGCTGCTGTCAATGCATTGCATGGCAGGTGGTTTGCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAAC
CTGTTTCCTGATTCTATGACAGCAACACAGCTACTGGTTCCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTT
CTTTCTTGAGAATTCATCTTGAGTTATCTTTTATTTAGATAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTA
CCTTGAAAAAATAAAAATGTTAACAGGAATGCAGTGTGCTCATTCTCCCTAAATAGTAAATCCCACTGTATACAAAACTGTTCTCTTGTT
CTGCCTTTTAAAATGTTCATGTAGAAAATTAATGAACTATAGGAATAGCTCTAGGAGAACAAATGTGCTTTCTGTAAAAAGGCAGACCAG
GGATGTAATGTTTTTAATGTTTCAGAAGCCTAACTTTTTACACAGTGGTTACATTTCACATTTCACTAATGTTGATATTTGGCTGATGGT
TGAGCAGTTTCTGAAATACACATTTAGTGTATGGAAATACAAGACAGCTAAAGGGCTGTTTGGTTAGCATCTCATCTTGCATTCTGATCA
ATTGGCAAGAAAGGGAGATTTCAAAATTATATTTCTTGATGGTATCTTTTCAATTAATGTATCTGTAAAAGTTTCTTTGTAAATACTATG
TGTTCTGGTGTGTCTTAAAATTCCAAACAAAATGATCCCTGCATTTCCTGAAGATGTTTAAACGTGAGAGTCTGGTAGGCAAAGCAGTCT
GAGAAAGAAATAGGAAATGCAGAAATAGGTTTTGTCTGGTTGCATATAATCTTTGCTCTTTTTAAGCTCTGTGAGCTCTGAAATATATTT
TTGGGTTACTTCAGTGTGTTTGACAAGACAGCTTGATATTTCTATCAAACAAATGACTTTCATATTGCAACAATCTTTGTAAGAACCACT

>50297_50297_5_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000308370_RBM39_chr20_34301018_ENST00000253363_length(amino acids)=707AA_BP=542
MPRPGTSGRRPLLLVLLLPLFAAATSAASPSPSPSQVVEVPGVPSRPASVAVCRCCPGQTSRRSRCIRAFCRVRSCQPKKCAGPQRCLNP
VPAVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFC
QLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVL
AQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDE
CATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPF
GSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIP
ESGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEE

--------------------------------------------------------------
>50297_50297_6_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000308370_RBM39_chr20_34301018_ENST00000361162_length(transcript)=2977nt_BP=1627nt
ATGCCGAGGCCTGGCACCAGCGGCCGCCGCCCCCTCCTGCTGGTGCTGTTGCTGCCGCTCTTCGCAGCCGCCACCTCCGCCGCCAGCCCC
AGCCCCAGCCCCAGCCAGGTCGTCGAGGTCCCGGGGGTCCCCAGCCGCCCGGCCAGCGTTGCTGTTTGTCGCTGCTGCCCGGGCCAGACG
TCTAGGAGGAGCCGCTGCATCCGAGCCTTCTGCAGGGTCCGAAGCTGCCAGCCCAAAAAGTGTGCAGGCCCCCAGCGGTGCCTGAACCCA
GTGCCTGCAGTGCCCAGTCCCAGCCCCAGCGTGAGGAAGAGACAGGTGTCCCTCAACTGGCAGCCACTGACGCTCCAGGAGGCCAGAGCT
CTACTGAAGCGGCGGCGGCCCCGGGGGCCAGGGGGCCGGGGACTACTGAGAAGGAGGCCCCCACAGCGTGCCCCCGCTGGCAAGGCCCCG
GTCCTGTGTCCCTTGATCTGTCACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGC
CAGTTGCACTCCTCGGGCGCCCGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGC
GACGACGAGCACGGCGTGGCATCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTG
TCTGGCCCTTGGGAGGAGGCGGACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTG
GCACAGAGCGCGCCGCGGGAGGACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCC
CCGCTGCCCGGGCTCCGGACGCAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGC
CTGGGGAACTCCGAAAGAGTGAGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAG
TGCGCGACTGGCGGGCGCTGCCAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGAC
TCGTCCCGCAGCAGCTGCATCTCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTG
CCCATTCTGCGGAACATCACTAAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTC
GGCTCAGAGGGTTTCCGGGAGATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGC
CAGGAGCCACCCCGAGTGTCACTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTG
GAGCCCCGGCCTGAACCCCGGCCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCT
GAATCAGGTACAGGTTTGCAGATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGATTTG
CAAACAAGACTTTCCCAGCAGACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACACAATGTTTCCAACTCTCT
AACATGTTTAACCCTCAAACAGAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAATGTAATAAACATGGAGGA
GTTATTCATATTTATGTTGACAAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCAGCTATTGCTGCTGTCAAT
GCATTGCATGGCAGGTGGTTTGCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAACCTGTTTCCTGATTCTATG
ACAGCAACACAGCTACTGGTTCCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTTCTTTCTTGAGAATTCATC
TTGAGTTATCTTTTATTTAGATAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTACCTTGAAAAAATAAAAAT
GTTAACAGGAATGCAGTGTGCTCATTCTCCCTAAATAGTAAATCCCACTGTATACAAAACTGTTCTCTTGTTCTGCCTTTTAAAATGTTC
ATGTAGAAAATTAATGAACTATAGGAATAGCTCTAGGAGAACAAATGTGCTTTCTGTAAAAAGGCAGACCAGGGATGTAATGTTTTTAAT
GTTTCAGAAGCCTAACTTTTTACACAGTGGTTACATTTCACATTTCACTAATGTTGATATTTGGCTGATGGTTGAGCAGTTTCTGAAATA
CACATTTAGTGTATGGAAATACAAGACAGCTAAAGGGCTGTTTGGTTAGCATCTCATCTTGCATTCTGATCAATTGGCAAGAAAGGGAGA
TTTCAAAATTATATTTCTTGATGGTATCTTTTCAATTAATGTATCTGTAAAAGTTTCTTTGTAAATACTATGTGTTCTGGTGTGTCTTAA
AATTCCAAACAAAATGATCCCTGCATTTCCTGAAGATGTTTAAACGTGAGAGTCTGGTAGGCAAAGCAGTCTGAGAAAGAAATAGGAAAT
GCAGAAATAGGTTTTGTCTGGTTGCATATAATCTTTGCTCTTTTTAAGCTCTGTGAGCTCTGAAATATATTTTTGGGTTACTTCAGTGTG
TTTGACAAGACAGCTTGATATTTCTATCAAACAAATGACTTTCATATTGCAACAATCTTTGTAAGAACCACTCAAATAAAAGTCTCTTAA

>50297_50297_6_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000308370_RBM39_chr20_34301018_ENST00000361162_length(amino acids)=701AA_BP=542
MPRPGTSGRRPLLLVLLLPLFAAATSAASPSPSPSQVVEVPGVPSRPASVAVCRCCPGQTSRRSRCIRAFCRVRSCQPKKCAGPQRCLNP
VPAVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFC
QLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVL
AQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDE
CATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPF
GSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIP
ESGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGG

--------------------------------------------------------------
>50297_50297_7_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000308370_RBM39_chr20_34301018_ENST00000407261_length(transcript)=2277nt_BP=1627nt
ATGCCGAGGCCTGGCACCAGCGGCCGCCGCCCCCTCCTGCTGGTGCTGTTGCTGCCGCTCTTCGCAGCCGCCACCTCCGCCGCCAGCCCC
AGCCCCAGCCCCAGCCAGGTCGTCGAGGTCCCGGGGGTCCCCAGCCGCCCGGCCAGCGTTGCTGTTTGTCGCTGCTGCCCGGGCCAGACG
TCTAGGAGGAGCCGCTGCATCCGAGCCTTCTGCAGGGTCCGAAGCTGCCAGCCCAAAAAGTGTGCAGGCCCCCAGCGGTGCCTGAACCCA
GTGCCTGCAGTGCCCAGTCCCAGCCCCAGCGTGAGGAAGAGACAGGTGTCCCTCAACTGGCAGCCACTGACGCTCCAGGAGGCCAGAGCT
CTACTGAAGCGGCGGCGGCCCCGGGGGCCAGGGGGCCGGGGACTACTGAGAAGGAGGCCCCCACAGCGTGCCCCCGCTGGCAAGGCCCCG
GTCCTGTGTCCCTTGATCTGTCACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGC
CAGTTGCACTCCTCGGGCGCCCGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGC
GACGACGAGCACGGCGTGGCATCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTG
TCTGGCCCTTGGGAGGAGGCGGACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTG
GCACAGAGCGCGCCGCGGGAGGACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCC
CCGCTGCCCGGGCTCCGGACGCAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGC
CTGGGGAACTCCGAAAGAGTGAGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAG
TGCGCGACTGGCGGGCGCTGCCAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGAC
TCGTCCCGCAGCAGCTGCATCTCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTG
CCCATTCTGCGGAACATCACTAAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTC
GGCTCAGAGGGTTTCCGGGAGATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGC
CAGGAGCCACCCCGAGTGTCACTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTG
GAGCCCCGGCCTGAACCCCGGCCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCT
GAATCAGGTACAGGTTTGCAGATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGAATTC
TCTTTTGTTATAGATTTGCAAACAAGACTTTCCCAGCAGACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACA
CAATGTTTCCAACTCTCTAACATGTTTAACCCTCAAACAGAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAA
TGTAATAAACATGGAGGAGTTATTCATATTTATGTTGACAAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCA
GCTATTGCTGCTGTCAATGCATTGCATGGCAGGTGGTTTGCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAAC
CTGTTTCCTGATTCTATGACAGCAACACAGCTACTGGTTCCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTT
CTTTCTTGAGAATTCATCTTGAGTTATCTTTTATTTAGATAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTA

>50297_50297_7_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000308370_RBM39_chr20_34301018_ENST00000407261_length(amino acids)=707AA_BP=542
MPRPGTSGRRPLLLVLLLPLFAAATSAASPSPSPSQVVEVPGVPSRPASVAVCRCCPGQTSRRSRCIRAFCRVRSCQPKKCAGPQRCLNP
VPAVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFC
QLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVL
AQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDE
CATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPF
GSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIP
ESGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEE

--------------------------------------------------------------
>50297_50297_8_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000308370_RBM39_chr20_34301018_ENST00000528062_length(transcript)=2707nt_BP=1627nt
ATGCCGAGGCCTGGCACCAGCGGCCGCCGCCCCCTCCTGCTGGTGCTGTTGCTGCCGCTCTTCGCAGCCGCCACCTCCGCCGCCAGCCCC
AGCCCCAGCCCCAGCCAGGTCGTCGAGGTCCCGGGGGTCCCCAGCCGCCCGGCCAGCGTTGCTGTTTGTCGCTGCTGCCCGGGCCAGACG
TCTAGGAGGAGCCGCTGCATCCGAGCCTTCTGCAGGGTCCGAAGCTGCCAGCCCAAAAAGTGTGCAGGCCCCCAGCGGTGCCTGAACCCA
GTGCCTGCAGTGCCCAGTCCCAGCCCCAGCGTGAGGAAGAGACAGGTGTCCCTCAACTGGCAGCCACTGACGCTCCAGGAGGCCAGAGCT
CTACTGAAGCGGCGGCGGCCCCGGGGGCCAGGGGGCCGGGGACTACTGAGAAGGAGGCCCCCACAGCGTGCCCCCGCTGGCAAGGCCCCG
GTCCTGTGTCCCTTGATCTGTCACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGC
CAGTTGCACTCCTCGGGCGCCCGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGC
GACGACGAGCACGGCGTGGCATCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTG
TCTGGCCCTTGGGAGGAGGCGGACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTG
GCACAGAGCGCGCCGCGGGAGGACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCC
CCGCTGCCCGGGCTCCGGACGCAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGC
CTGGGGAACTCCGAAAGAGTGAGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAG
TGCGCGACTGGCGGGCGCTGCCAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGAC
TCGTCCCGCAGCAGCTGCATCTCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTG
CCCATTCTGCGGAACATCACTAAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTC
GGCTCAGAGGGTTTCCGGGAGATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGC
CAGGAGCCACCCCGAGTGTCACTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTG
GAGCCCCGGCCTGAACCCCGGCCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCT
GAATCAGGTACAGGTTTGCAGATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGAATTC
TCTTTTGTTATAGATTTGCAAACAAGACTTTCCCAGCAGACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACA
CAATGTTTCCAACTCTCTAACATGTTTAACCCTCAAACAGAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAA
TGTAATAAACATGGAGGAGTTATTCATATTTATGTTGACAAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCA
GCTATTGCTGCTGTCAATGCATTGCATGGCAGGTGGTTTGCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAAC
CTGTTTCCTGATTCTATGACAGCAACACAGCTACTGGTTCCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTT
CTTTCTTGAGAATTCATCTTGAGTTATCTTTTATTTAGATAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTA
CCTTGAAAAAATAAAAATGTTAACAGGAATGCAGTGTGCTCATTCTCCCTAAATAGTAAATCCCACTGTATACAAAACTGTTCTCTTGTT
CTGCCTTTTAAAATGTTCATGTAGAAAATTAATGAACTATAGGAATAGCTCTAGGAGAACAAATGTGCTTTCTGTAAAAAGGCAGACCAG
GGATGTAATGTTTTTAATGTTTCAGAAGCCTAACTTTTTACACAGTGGTTACATTTCACATTTCACTAATGTTGATATTTGGCTGATGGT
TGAGCAGTTTCTGAAATACACATTTAGTGTATGGAAATACAAGACAGCTAAAGGGCTGTTTGGTTAGCATCTCATCTTGCATTCTGATCA
ATTGGCAAGAAAGGGAGATTTCAAAATTATATTTCTTGATGGTATCTTTTCAATTAATGTATCTGTAAAAGTTTCTTTGTAAATACTATG

>50297_50297_8_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000308370_RBM39_chr20_34301018_ENST00000528062_length(amino acids)=707AA_BP=542
MPRPGTSGRRPLLLVLLLPLFAAATSAASPSPSPSQVVEVPGVPSRPASVAVCRCCPGQTSRRSRCIRAFCRVRSCQPKKCAGPQRCLNP
VPAVPSPSPSVRKRQVSLNWQPLTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFC
QLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAAAPYTVL
AQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDE
CATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCPPF
GSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIP
ESGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEE

--------------------------------------------------------------
>50297_50297_9_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000396819_RBM39_chr20_34301018_ENST00000253363_length(transcript)=2811nt_BP=1443nt
AGCGCGGCGCTGCAGCCATGGCGGGCGGCGTGCGGCTGCTCTGGGTGTCGCTATTGGTGCTGCTGGCGCAGCTAGGGCCGCAGCCTGGAC
TGGGCCGGCTCGGAGAGCGTCTCCGCGTGCGCTTCACCCCGGTCGTGTGCGGCCTGCGCTGCGTCCATGGGCCGACCGGCTCCCGCTGTA
CCCCGACCTGCGCGCCCCGCAACGCCACCAGCGTGGACAGCGGCGCTCCCGGCGGGGCGGCCCCGGGGGGACCCGGCTTCCGCGCCTTCC
TGTGTCCCTTGATCTGTCACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGCCAGT
TGCACTCCTCGGGCGCCCGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGCGACG
ACGAGCACGGCGTGGCATCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTGTCTG
GCCCTTGGGAGGAGGCGGACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTGGCAC
AGAGCGCGCCGCGGGAGGACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCCCCGC
TGCCCGGGCTCCGGACGCAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGCCTGG
GGAACTCCGAAAGAGTGAGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAGTGCG
CGACTGGCGGGCGCTGCCAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGACTCGT
CCCGCAGCAGCTGCATCTCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTGCCCA
TTCTGCGGAACATCACTAAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTCGGCT
CAGAGGGTTTCCGGGAGATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGCCAGG
AGCCACCCCGAGTGTCACTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTGGAGC
CCCGGCCTGAACCCCGGCCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCTGAAT
CAGGTACAGGTTTGCAGATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGAATTCTCTT
TTGTTATAGATTTGCAAACAAGACTTTCCCAGCAGACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACACAAT
GTTTCCAACTCTCTAACATGTTTAACCCTCAAACAGAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAATGTA
ATAAACATGGAGGAGTTATTCATATTTATGTTGACAAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCAGCTA
TTGCTGCTGTCAATGCATTGCATGGCAGGTGGTTTGCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAACCTGT
TTCCTGATTCTATGACAGCAACACAGCTACTGGTTCCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTTCTTT
CTTGAGAATTCATCTTGAGTTATCTTTTATTTAGATAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTACCTT
GAAAAAATAAAAATGTTAACAGGAATGCAGTGTGCTCATTCTCCCTAAATAGTAAATCCCACTGTATACAAAACTGTTCTCTTGTTCTGC
CTTTTAAAATGTTCATGTAGAAAATTAATGAACTATAGGAATAGCTCTAGGAGAACAAATGTGCTTTCTGTAAAAAGGCAGACCAGGGAT
GTAATGTTTTTAATGTTTCAGAAGCCTAACTTTTTACACAGTGGTTACATTTCACATTTCACTAATGTTGATATTTGGCTGATGGTTGAG
CAGTTTCTGAAATACACATTTAGTGTATGGAAATACAAGACAGCTAAAGGGCTGTTTGGTTAGCATCTCATCTTGCATTCTGATCAATTG
GCAAGAAAGGGAGATTTCAAAATTATATTTCTTGATGGTATCTTTTCAATTAATGTATCTGTAAAAGTTTCTTTGTAAATACTATGTGTT
CTGGTGTGTCTTAAAATTCCAAACAAAATGATCCCTGCATTTCCTGAAGATGTTTAAACGTGAGAGTCTGGTAGGCAAAGCAGTCTGAGA
AAGAAATAGGAAATGCAGAAATAGGTTTTGTCTGGTTGCATATAATCTTTGCTCTTTTTAAGCTCTGTGAGCTCTGAAATATATTTTTGG
GTTACTTCAGTGTGTTTGACAAGACAGCTTGATATTTCTATCAAACAAATGACTTTCATATTGCAACAATCTTTGTAAGAACCACTCAAA

>50297_50297_9_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000396819_RBM39_chr20_34301018_ENST00000253363_length(amino acids)=640AA_BP=475
MAGGVRLLWVSLLVLLAQLGPQPGLGRLGERLRVRFTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLIC
HNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEA
DAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERV
SAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNIT
KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR
PDPRPGPELPLPSIPAWTGPEIPESGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSN
MFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMT

--------------------------------------------------------------
>50297_50297_10_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000396819_RBM39_chr20_34301018_ENST00000361162_length(transcript)=2793nt_BP=1443nt
AGCGCGGCGCTGCAGCCATGGCGGGCGGCGTGCGGCTGCTCTGGGTGTCGCTATTGGTGCTGCTGGCGCAGCTAGGGCCGCAGCCTGGAC
TGGGCCGGCTCGGAGAGCGTCTCCGCGTGCGCTTCACCCCGGTCGTGTGCGGCCTGCGCTGCGTCCATGGGCCGACCGGCTCCCGCTGTA
CCCCGACCTGCGCGCCCCGCAACGCCACCAGCGTGGACAGCGGCGCTCCCGGCGGGGCGGCCCCGGGGGGACCCGGCTTCCGCGCCTTCC
TGTGTCCCTTGATCTGTCACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGCCAGT
TGCACTCCTCGGGCGCCCGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGCGACG
ACGAGCACGGCGTGGCATCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTGTCTG
GCCCTTGGGAGGAGGCGGACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTGGCAC
AGAGCGCGCCGCGGGAGGACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCCCCGC
TGCCCGGGCTCCGGACGCAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGCCTGG
GGAACTCCGAAAGAGTGAGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAGTGCG
CGACTGGCGGGCGCTGCCAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGACTCGT
CCCGCAGCAGCTGCATCTCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTGCCCA
TTCTGCGGAACATCACTAAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTCGGCT
CAGAGGGTTTCCGGGAGATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGCCAGG
AGCCACCCCGAGTGTCACTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTGGAGC
CCCGGCCTGAACCCCGGCCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCTGAAT
CAGGTACAGGTTTGCAGATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGATTTGCAAA
CAAGACTTTCCCAGCAGACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACACAATGTTTCCAACTCTCTAACA
TGTTTAACCCTCAAACAGAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAATGTAATAAACATGGAGGAGTTA
TTCATATTTATGTTGACAAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCAGCTATTGCTGCTGTCAATGCAT
TGCATGGCAGGTGGTTTGCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAACCTGTTTCCTGATTCTATGACAG
CAACACAGCTACTGGTTCCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTTCTTTCTTGAGAATTCATCTTGA
GTTATCTTTTATTTAGATAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTACCTTGAAAAAATAAAAATGTTA
ACAGGAATGCAGTGTGCTCATTCTCCCTAAATAGTAAATCCCACTGTATACAAAACTGTTCTCTTGTTCTGCCTTTTAAAATGTTCATGT
AGAAAATTAATGAACTATAGGAATAGCTCTAGGAGAACAAATGTGCTTTCTGTAAAAAGGCAGACCAGGGATGTAATGTTTTTAATGTTT
CAGAAGCCTAACTTTTTACACAGTGGTTACATTTCACATTTCACTAATGTTGATATTTGGCTGATGGTTGAGCAGTTTCTGAAATACACA
TTTAGTGTATGGAAATACAAGACAGCTAAAGGGCTGTTTGGTTAGCATCTCATCTTGCATTCTGATCAATTGGCAAGAAAGGGAGATTTC
AAAATTATATTTCTTGATGGTATCTTTTCAATTAATGTATCTGTAAAAGTTTCTTTGTAAATACTATGTGTTCTGGTGTGTCTTAAAATT
CCAAACAAAATGATCCCTGCATTTCCTGAAGATGTTTAAACGTGAGAGTCTGGTAGGCAAAGCAGTCTGAGAAAGAAATAGGAAATGCAG
AAATAGGTTTTGTCTGGTTGCATATAATCTTTGCTCTTTTTAAGCTCTGTGAGCTCTGAAATATATTTTTGGGTTACTTCAGTGTGTTTG
ACAAGACAGCTTGATATTTCTATCAAACAAATGACTTTCATATTGCAACAATCTTTGTAAGAACCACTCAAATAAAAGTCTCTTAAAAAG

>50297_50297_10_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000396819_RBM39_chr20_34301018_ENST00000361162_length(amino acids)=634AA_BP=475
MAGGVRLLWVSLLVLLAQLGPQPGLGRLGERLRVRFTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLIC
HNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEA
DAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERV
SAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNIT
KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR
PDPRPGPELPLPSIPAWTGPEIPESGTGLQIPPAAQQALQMSGSLAFGAVADLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQT
EEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMTATQLLV

--------------------------------------------------------------
>50297_50297_11_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000396819_RBM39_chr20_34301018_ENST00000407261_length(transcript)=2093nt_BP=1443nt
AGCGCGGCGCTGCAGCCATGGCGGGCGGCGTGCGGCTGCTCTGGGTGTCGCTATTGGTGCTGCTGGCGCAGCTAGGGCCGCAGCCTGGAC
TGGGCCGGCTCGGAGAGCGTCTCCGCGTGCGCTTCACCCCGGTCGTGTGCGGCCTGCGCTGCGTCCATGGGCCGACCGGCTCCCGCTGTA
CCCCGACCTGCGCGCCCCGCAACGCCACCAGCGTGGACAGCGGCGCTCCCGGCGGGGCGGCCCCGGGGGGACCCGGCTTCCGCGCCTTCC
TGTGTCCCTTGATCTGTCACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGCCAGT
TGCACTCCTCGGGCGCCCGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGCGACG
ACGAGCACGGCGTGGCATCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTGTCTG
GCCCTTGGGAGGAGGCGGACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTGGCAC
AGAGCGCGCCGCGGGAGGACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCCCCGC
TGCCCGGGCTCCGGACGCAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGCCTGG
GGAACTCCGAAAGAGTGAGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAGTGCG
CGACTGGCGGGCGCTGCCAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGACTCGT
CCCGCAGCAGCTGCATCTCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTGCCCA
TTCTGCGGAACATCACTAAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTCGGCT
CAGAGGGTTTCCGGGAGATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGCCAGG
AGCCACCCCGAGTGTCACTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTGGAGC
CCCGGCCTGAACCCCGGCCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCTGAAT
CAGGTACAGGTTTGCAGATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGAATTCTCTT
TTGTTATAGATTTGCAAACAAGACTTTCCCAGCAGACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACACAAT
GTTTCCAACTCTCTAACATGTTTAACCCTCAAACAGAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAATGTA
ATAAACATGGAGGAGTTATTCATATTTATGTTGACAAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCAGCTA
TTGCTGCTGTCAATGCATTGCATGGCAGGTGGTTTGCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAACCTGT
TTCCTGATTCTATGACAGCAACACAGCTACTGGTTCCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTTCTTT
CTTGAGAATTCATCTTGAGTTATCTTTTATTTAGATAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTACCTT

>50297_50297_11_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000396819_RBM39_chr20_34301018_ENST00000407261_length(amino acids)=640AA_BP=475
MAGGVRLLWVSLLVLLAQLGPQPGLGRLGERLRVRFTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLIC
HNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEA
DAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERV
SAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNIT
KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR
PDPRPGPELPLPSIPAWTGPEIPESGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSN
MFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMT

--------------------------------------------------------------
>50297_50297_12_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000396819_RBM39_chr20_34301018_ENST00000528062_length(transcript)=2523nt_BP=1443nt
AGCGCGGCGCTGCAGCCATGGCGGGCGGCGTGCGGCTGCTCTGGGTGTCGCTATTGGTGCTGCTGGCGCAGCTAGGGCCGCAGCCTGGAC
TGGGCCGGCTCGGAGAGCGTCTCCGCGTGCGCTTCACCCCGGTCGTGTGCGGCCTGCGCTGCGTCCATGGGCCGACCGGCTCCCGCTGTA
CCCCGACCTGCGCGCCCCGCAACGCCACCAGCGTGGACAGCGGCGCTCCCGGCGGGGCGGCCCCGGGGGGACCCGGCTTCCGCGCCTTCC
TGTGTCCCTTGATCTGTCACAATGGCGGTGTGTGCGTGAAGCCTGACCGCTGCCTCTGTCCCCCGGACTTCGCTGGCAAGTTCTGCCAGT
TGCACTCCTCGGGCGCCCGGCCCCCGGCCCCGGCTGTACCAGGCCTCACCCGCTCCGTGTACACTATGCCACTGGCCAACCACCGCGACG
ACGAGCACGGCGTGGCATCTATGGTGAGCGTCCACGTGGAGCACCCGCAGGAGGCGTCGGTGGTGGTGCACCAGGTGGAGCGTGTGTCTG
GCCCTTGGGAGGAGGCGGACGCTGAGGCGGTGGCGCGGGCGGAAGCGGCGGCGCGGGCGGAGGCGGCAGCGCCCTACACGGTGTTGGCAC
AGAGCGCGCCGCGGGAGGACGGCTACTCAGATGCCTCGGGCTTCGGTTACTGCTTTCGGGAGCTGCGCGGAGGCGAATGCGCGTCCCCGC
TGCCCGGGCTCCGGACGCAGGAGGTCTGCTGCCGAGGGGCCGGCTTGGCCTGGGGCGTTCACGACTGTCAGCTGTGCTCCGAGCGCCTGG
GGAACTCCGAAAGAGTGAGCGCCCCAGATGGACCTTGTCCAACCGGCTTTGAAAGAGTTAATGGGTCCTGCGAAGATGTGGATGAGTGCG
CGACTGGCGGGCGCTGCCAGCACGGCGAGTGTGCAAACACGCGCGGCGGGTACACGTGTGTGTGCCCCGACGGCTTTCTGCTCGACTCGT
CCCGCAGCAGCTGCATCTCCCAACACGTGATCTCAGAGGCCAAAGGGCCCTGCTTCCGCGTGCTCCGCGACGGCGGCTGTTCGCTGCCCA
TTCTGCGGAACATCACTAAACAGATCTGCTGCTGCAGCCGCGTAGGCAAGGCCTGGGGCCGGGGCTGCCAGCTCTGCCCACCCTTCGGCT
CAGAGGGTTTCCGGGAGATCTGCCCGGCTGGTCCTGGTTACCACTACTCGGCCTCCGACCTCCGCTACAACACCAGACCCCTGGGCCAGG
AGCCACCCCGAGTGTCACTCAGCCAGCCTCGTACCCTGCCAGCCACCTCTCGGCCATCTGCAGGCTTTCTGCCCACCCATCGCCTGGAGC
CCCGGCCTGAACCCCGGCCCGATCCCCGGCCCGGCCCTGAGCTTCCCTTGCCCAGCATCCCTGCCTGGACTGGTCCTGAGATTCCTGAAT
CAGGTACAGGTTTGCAGATTCCGCCAGCAGCACAGCAAGCTCTACAGATGAGTGGCTCTTTGGCATTTGGTGCTGTGGCAGAATTCTCTT
TTGTTATAGATTTGCAAACAAGACTTTCCCAGCAGACTGAAGCTTCAGCTTTAGCTGCAGCTGCCTCTGTTCAGCCACTTGCAACACAAT
GTTTCCAACTCTCTAACATGTTTAACCCTCAAACAGAAGAAGAAGTTGGATGGGATACCGAGATTAAGGATGATGTGATTGAAGAATGTA
ATAAACATGGAGGAGTTATTCATATTTATGTTGACAAAAATTCAGCTCAGGGCAATGTGTATGTGAAGTGCCCATCAATTGCTGCAGCTA
TTGCTGCTGTCAATGCATTGCATGGCAGGTGGTTTGCTGGTAAAATGATAACAGCAGCATATGTACCTCTTCCAACTTACCACAACCTGT
TTCCTGATTCTATGACAGCAACACAGCTACTGGTTCCAAGTAGACGATGAAGGAAGATATAGTCCCTTATGTATATAGCTTTTTTTCTTT
CTTGAGAATTCATCTTGAGTTATCTTTTATTTAGATAAAAATAAAGAGGCAAGGATCTACTGTCATTTGTATGCAATTTCCTGTTACCTT
GAAAAAATAAAAATGTTAACAGGAATGCAGTGTGCTCATTCTCCCTAAATAGTAAATCCCACTGTATACAAAACTGTTCTCTTGTTCTGC
CTTTTAAAATGTTCATGTAGAAAATTAATGAACTATAGGAATAGCTCTAGGAGAACAAATGTGCTTTCTGTAAAAAGGCAGACCAGGGAT
GTAATGTTTTTAATGTTTCAGAAGCCTAACTTTTTACACAGTGGTTACATTTCACATTTCACTAATGTTGATATTTGGCTGATGGTTGAG
CAGTTTCTGAAATACACATTTAGTGTATGGAAATACAAGACAGCTAAAGGGCTGTTTGGTTAGCATCTCATCTTGCATTCTGATCAATTG
GCAAGAAAGGGAGATTTCAAAATTATATTTCTTGATGGTATCTTTTCAATTAATGTATCTGTAAAAGTTTCTTTGTAAATACTATGTGTT

>50297_50297_12_LTBP4-RBM39_LTBP4_chr19_41114509_ENST00000396819_RBM39_chr20_34301018_ENST00000528062_length(amino acids)=640AA_BP=475
MAGGVRLLWVSLLVLLAQLGPQPGLGRLGERLRVRFTPVVCGLRCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGPGFRAFLCPLIC
HNGGVCVKPDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEA
DAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERV
SAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNIT
KQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPR
PDPRPGPELPLPSIPAWTGPEIPESGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSN
MFNPQTEEEVGWDTEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPLPTYHNLFPDSMT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for LTBP4-RBM39


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneRBM39chr19:41114509chr20:34301018ENST00000528062916355_406343.3333333333333509.0ESR1 and ESR2
TgeneRBM39chr19:41114509chr20:34301018ENST000002533631017406_530365.3333333333333531.0NCOA6
TgeneRBM39chr19:41114509chr20:34301018ENST000003611621017406_530365.3333333333333525.0NCOA6
TgeneRBM39chr19:41114509chr20:34301018ENST00000528062916406_530343.3333333333333509.0NCOA6


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneRBM39chr19:41114509chr20:34301018ENST000002533631017355_406365.3333333333333531.0ESR1 and ESR2
TgeneRBM39chr19:41114509chr20:34301018ENST000003611621017355_406365.3333333333333525.0ESR1 and ESR2
TgeneRBM39chr19:41114509chr20:34301018ENST000002533631017291_406365.3333333333333531.0JUN
TgeneRBM39chr19:41114509chr20:34301018ENST000003611621017291_406365.3333333333333525.0JUN
TgeneRBM39chr19:41114509chr20:34301018ENST00000528062916291_406343.3333333333333509.0JUN


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LTBP4-RBM39


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LTBP4-RBM39


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource