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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LUC7L-STXBP1 (FusionGDB2 ID:50376)

Fusion Gene Summary for LUC7L-STXBP1

check button Fusion gene summary
Fusion gene informationFusion gene name: LUC7L-STXBP1
Fusion gene ID: 50376
HgeneTgene
Gene symbol

LUC7L

STXBP1

Gene ID

55692

6812

Gene nameLUC7 likesyntaxin binding protein 1
SynonymsLUC7B1|Luc7|SR+89|hLuc7B1MUNC18-1|N-Sec1|NSEC1|P67|RBSEC1|UNC18|unc-18A|unc18-1
Cytomap

16p13.3

9q34.11

Type of geneprotein-codingprotein-coding
Descriptionputative RNA-binding protein Luc7-like 1putative SR protein LUC7B1sarcoplasmic reticulum protein LUC7B1syntaxin-binding protein 1neuronal SEC1protein unc-18 homolog 1protein unc-18 homolog A
Modification date2020032020200313
UniProtAcc

Q9NQ29

.
Ensembl transtripts involved in fusion geneENST00000293872, ENST00000337351, 
ENST00000397780, ENST00000397783, 
ENST00000494366, 		ENST00000481942, 
ENST00000373299, ENST00000373302, 
Fusion gene scores* DoF score19 X 17 X 10=323013 X 13 X 7=1183
# samples 2513
** MAII scorelog2(25/3230*10)=-3.6915341649192
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/1183*10)=-3.18586654531133
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LUC7L [Title/Abstract] AND STXBP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLUC7L(256003)-STXBP1(130425484), # samples:3
Anticipated loss of major functional domain due to fusion event.LUC7L-STXBP1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSTXBP1

GO:0072659

protein localization to plasma membrane

17543282


check buttonFusion gene breakpoints across LUC7L (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across STXBP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCECTCGA-A5-A7WK-01ALUC7Lchr16

256003

-STXBP1chr9

130425484

+
ChimerDB4UCECTCGA-A5-A7WKLUC7Lchr16

256003

-STXBP1chr9

130425484

+


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Fusion Gene ORF analysis for LUC7L-STXBP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000293872ENST00000481942LUC7Lchr16

256003

-STXBP1chr9

130425484

+
5CDS-intronENST00000337351ENST00000481942LUC7Lchr16

256003

-STXBP1chr9

130425484

+
5CDS-intronENST00000397780ENST00000481942LUC7Lchr16

256003

-STXBP1chr9

130425484

+
5CDS-intronENST00000397783ENST00000481942LUC7Lchr16

256003

-STXBP1chr9

130425484

+
Frame-shiftENST00000397780ENST00000373299LUC7Lchr16

256003

-STXBP1chr9

130425484

+
Frame-shiftENST00000397780ENST00000373302LUC7Lchr16

256003

-STXBP1chr9

130425484

+
In-frameENST00000293872ENST00000373299LUC7Lchr16

256003

-STXBP1chr9

130425484

+
In-frameENST00000293872ENST00000373302LUC7Lchr16

256003

-STXBP1chr9

130425484

+
In-frameENST00000337351ENST00000373299LUC7Lchr16

256003

-STXBP1chr9

130425484

+
In-frameENST00000337351ENST00000373302LUC7Lchr16

256003

-STXBP1chr9

130425484

+
In-frameENST00000397783ENST00000373299LUC7Lchr16

256003

-STXBP1chr9

130425484

+
In-frameENST00000397783ENST00000373302LUC7Lchr16

256003

-STXBP1chr9

130425484

+
intron-3CDSENST00000494366ENST00000373299LUC7Lchr16

256003

-STXBP1chr9

130425484

+
intron-3CDSENST00000494366ENST00000373302LUC7Lchr16

256003

-STXBP1chr9

130425484

+
intron-intronENST00000494366ENST00000481942LUC7Lchr16

256003

-STXBP1chr9

130425484

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000293872LUC7Lchr16256003-ENST00000373302STXBP1chr9130425484+39626211112003630
ENST00000293872LUC7Lchr16256003-ENST00000373299STXBP1chr9130425484+38366211111976621
ENST00000337351LUC7Lchr16256003-ENST00000373302STXBP1chr9130425484+39756341242016630
ENST00000337351LUC7Lchr16256003-ENST00000373299STXBP1chr9130425484+38496341241989621
ENST00000397783LUC7Lchr16256003-ENST00000373302STXBP1chr9130425484+39756341242016630
ENST00000397783LUC7Lchr16256003-ENST00000373299STXBP1chr9130425484+38496341241989621

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000293872ENST00000373302LUC7Lchr16256003-STXBP1chr9130425484+0.0016064970.9983935
ENST00000293872ENST00000373299LUC7Lchr16256003-STXBP1chr9130425484+0.0017307980.9982692
ENST00000337351ENST00000373302LUC7Lchr16256003-STXBP1chr9130425484+0.0016277090.9983724
ENST00000337351ENST00000373299LUC7Lchr16256003-STXBP1chr9130425484+0.001731030.99826896
ENST00000397783ENST00000373302LUC7Lchr16256003-STXBP1chr9130425484+0.0016277090.9983724
ENST00000397783ENST00000373299LUC7Lchr16256003-STXBP1chr9130425484+0.001731030.99826896

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Fusion Genomic Features for LUC7L-STXBP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
LUC7Lchr16256002-STXBP1chr9130425483+5.67E-111
LUC7Lchr16256002-STXBP1chr9130425483+5.67E-111
LUC7Lchr16256002-STXBP1chr9130425483+5.67E-111
LUC7Lchr16256002-STXBP1chr9130425483+5.67E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for LUC7L-STXBP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:256003/chr9:130425484)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LUC7L

Q9NQ29

.
FUNCTION: May bind to RNA via its Arg/Ser-rich domain. {ECO:0000269|PubMed:11170747}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLUC7Lchr16:256003chr9:130425484ENST00000293872-510218_259170372.0Coiled coilOntology_term=ECO:0000255
HgeneLUC7Lchr16:256003chr9:130425484ENST00000293872-51087_177170372.0Coiled coilOntology_term=ECO:0000255
HgeneLUC7Lchr16:256003chr9:130425484ENST00000337351-59218_259170326.0Coiled coilOntology_term=ECO:0000255
HgeneLUC7Lchr16:256003chr9:130425484ENST00000337351-5987_177170326.0Coiled coilOntology_term=ECO:0000255
HgeneLUC7Lchr16:256003chr9:130425484ENST00000397783-510218_259170424.0Coiled coilOntology_term=ECO:0000255
HgeneLUC7Lchr16:256003chr9:130425484ENST00000397783-51087_177170424.0Coiled coilOntology_term=ECO:0000255
HgeneLUC7Lchr16:256003chr9:130425484ENST00000293872-510243_362170372.0Compositional biasNote=Arg/Ser-rich
HgeneLUC7Lchr16:256003chr9:130425484ENST00000337351-59243_362170326.0Compositional biasNote=Arg/Ser-rich
HgeneLUC7Lchr16:256003chr9:130425484ENST00000397783-510243_362170424.0Compositional biasNote=Arg/Ser-rich


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Fusion Gene Sequence for LUC7L-STXBP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>50376_50376_1_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000293872_STXBP1_chr9_130425484_ENST00000373299_length(transcript)=3836nt_BP=621nt
GAAAGAGCCGAGTGGGCTCGAGGCCGACGCGACCATCGTTTGTCGACGCCGCTGCCACCGCCTGCCTGAGAGAAGTCGTCGCGGCCGACC
CCGTCGCCTCCGCCGGCTACCATGTCCGCCCAGGCGCAGATGCGGGCCCTGCTGGACCAGCTCATGGGCACGGCTCGGGACGGAGACGAA
ACCAGACAGAGGGTCAAGTTTACAGATGACCGTGTCTGCAAGAGTCACCTTCTGGACTGCTGCCCCCATGACATCCTGGCTGGGACGCGC
ATGGATTTAGGAGAATGTACCAAAATCCACGACTTGGCCCTCCGAGCAGATTATGAGATTGCAAGTAAAGAAAGAGACCTGTTTTTTGAA
TTAGATGCAATGGATCACTTGGAGTCCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAG
GAAATCAGTGCGGAAGTTTCTGCAAAGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTA
GGGGCTGAAGGTAATGTGGATGAATCCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGTCTATTCC
TTGGACTCTGCTGACTCTTTCCAAAGCTTCTACAGTCCCCACAAGGCTCAGATGAAGAATCCTATACTGGAGCGCCTGGCAGAGCAGATC
GCGACCCTTTGTGCCACCCTGAAGGAGTACCCGGCTGTGCGGTATCGGGGGGAATACAAGGACAATGCCCTGCTGGCTCAGCTAATCCAG
GACAAGCTCGATGCCTATAAAGCTGATGATCCAACAATGGGGGAGGGCCCAGACAAGGCACGCTCCCAGCTCCTGATCCTGGATCGAGGC
TTTGACCCCAGCTCCCCTGTGCTCCATGAATTGACTTTTCAGGCTATGAGTTATGATCTGCTGCCTATCGAAAATGATGTATACAAGTAT
GAGACCAGCGGCATCGGGGAGGCACGGGTGAAGGAGGTGCTCCTGGACGAGGACGACGACCTGTGGATAGCACTGCGCCACAAGCACATC
GCAGAGGTGTCCCAGGAAGTCACCCGGTCTCTGAAAGATTTTTCTTCTAGCAAGAGAATGAATACTGGAGAGAAGACCACCATGCGGGAC
CTGTCCCAGATGCTGAAGAAGATGCCTCAGTACCAGAAAGAGCTCAGCAAGTACTCCACCCACCTGCACCTTGCTGAGGACTGTATGAAG
CATTACCAAGGCACCGTAGACAAACTCTGCCGAGTGGAGCAGGACCTGGCCATGGGCACAGATGCTGAGGGAGAGAAGATCAAGGACCCT
ATGCGAGCCATCGTCCCCATTCTGCTGGATGCCAATGTCAGCACTTATGACAAAATCCGCATCATCCTTCTCTACATCTTTTTGAAGAAT
GGCATCACGGAGGAAAACCTGAACAAACTGATCCAGCACGCCCAGATACCCCCGGAGGATAGTGAGATCATCACCAACATGGCTCACCTC
GGCGTGCCCATCGTCACCGATTCCACGCTGCGTCGCCGGAGCAAGCCGGAGCGGAAGGAACGCATCAGCGAGCAGACCTACCAGCTCTCA
CGGTGGACTCCGATTATCAAGGACATCATGGAGGACACTATTGAGGACAAACTTGACACCAAACACTACCCTTATATCTCTACCCGTTCC
TCTGCCTCCTTCAGCACCACCGCCGTCAGCGCCCGCTATGGGCACTGGCATAAGAACAAGGCCCCAGGCGAGTACCGCAGTGGCCCCCGC
CTCATCATTTTCATCCTTGGGGGTGTGAGCCTGAATGAGATGCGCTGCGCCTACGAGGTGACCCAGGCCAACGGAAAGTGGGAGGTGCTG
ATAGGATCCACACACATCCTCACCCCACAGAAACTGCTGGACACACTGAAGAAACTGAATAAAACAGATGAAGAAATAAGCAGTTAAAAA
AATAAGTCGCCCCTCCAAAACACGCCCCCATCCCACAGCGCTCCGCAGCTTCCCACCACCGCCCGCCTCAGTTCCTTTGCGTCTGTTGCC
TCCCCAGCCCTGCACGCCCTGGCTGGCACTGTTGCCGCTGCATTCTCGTGTTCAGTGATGCCCTCTTCTTGTTTGAAACAAAAGAAAATA
ATGCATTGTGTTTTTTAAAAAGAGTATCTTATACATGTATCCTAAAAAGAGAAGCTCATGTGCAATTGGTGCACAGCAGGAGAAATTTCT
GGACTGTTAGGATGAATGGACGCCTTCTCCCCGTTATTTAAGATTTGTGACCTTGTACATAACCCTGGGTGACGTGCACATTGCTTGGGT
ATGGAACGGTAGAAATTTGGGTGTTTTTAAAACCTTGTTTGGGGTTGTTCCTGTCCTTGTTGAGAATCATAGAGATGTCTGTGTTCTTGG
AGTATTTCACACTGAGGACTAATCTGCTATCTTCATTCCAGTCCCTACCCCTCAGTGCCTGCTCTCATCCAAATAACCTGGGAGGTGACA
ATCAGGATATCTCAGGAGGTCCAAGGTGGAACAGACCTCTTTGCCTTTCCCAGCGTCTCATACCCCCGGTAGTGCAGCTGTGGGTGGAGG
CTGGGGTGTCTGCACGAAGTCAGGCCAGCGTCCTCCTCCACAGCCTGTCACTGCCCCCTCCCCAGCCTGTGTCCACAGTGCTGTGATCCC
GAGGGAAGTCCTCCAGTCTAAGTCACAGTGCCCTGACAGGTGAGAAGCAAACTCCCGCTGGAAGCCTCCATCTCTTTGGAAAAACAGTTA
GTCTGGAGCCTGTGGCCCAGGCCCTTCTGTCCCCAGGCATCATCCCAACAGCTCATTTTCCCTAGTCCGCCTTCGTTCAAGGGTCAGGAA
TGGACCAGAACAGATGGGTTCTGGAGGCCCCTGAACAGAGGGCTATGGCTGTGGAGAAGGTTCTTGGCCCGTTGGACTCACACAGACCCT
GTACCCTCTCGGCAAGCATCTTCAGTCAGATTATCCTCAGTTTCAGATACTTCATAATACCTTGTGTTGTGTGGGGTCATACATCATCGT
GTTTGTAAGAGAAGATGGTCATTTTATTCTCTGTATAAAACTTAGCTCTAAAGCAGAAACTAAAGCAGCAAATGCAGGAAGGCTGTCTCG
CCATCCTCAAGACTCAGCAGCTCTCATTCTCCAGTGGTGAGCACACCATTTGTGCTGCTGCTGTTGTCGTGAAATATAATAACAGTGGAA
GTCACAAAAATGTCCCCTGCCCAGCCCCCTCGCCGCCCTTGACCTCCTGCAGGCCATGTGTGTATTACTTGTCTAGTGATGTCCTCTCAA
AGTGCTGTACGCGAGCTCGGCGCCACCTCCGCCTCCCTTTCAGAGCCTGCTCCCCGCCCTCTCTGCTCGCTGCATTGTGGTGTTCTCTTC
TCAAGGCTTTGAAATCTCCCCTTGCACTGAGATTAGTCGTCAGATCTCTCCCCGTCTCCCTCCCAACTTATACGACCTGATTTCCTTAGG
ACGGAACCGCAGGCACCTGCGCCGGGCGTCTTACTCCCGCTGCTTGTTCTGTCCCCTCCCTCGGACCAAACAGTGCTCATGCTTCAGGAC
CTTGTTTGTCGAAGATGTTGGTTTCCCTTTCTCTGTTATTTATATAAAAATAATTTATCAAAAGGATATTTTAAAAAAGCTAGTCTGTCT
TGAAACTTGTTTACCTTAAAATTATCAGAATCTCAGTGTTTGAAAGTACTGAAGCACAAACATATATCATCTCTGTACCATTCTGTACTA

>50376_50376_1_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000293872_STXBP1_chr9_130425484_ENST00000373299_length(amino acids)=621AA_BP=170
MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHL
ESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEVYSLDSADSF
QSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPV
LHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKK
MPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENL
NKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTT

--------------------------------------------------------------
>50376_50376_2_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000293872_STXBP1_chr9_130425484_ENST00000373302_length(transcript)=3962nt_BP=621nt
GAAAGAGCCGAGTGGGCTCGAGGCCGACGCGACCATCGTTTGTCGACGCCGCTGCCACCGCCTGCCTGAGAGAAGTCGTCGCGGCCGACC
CCGTCGCCTCCGCCGGCTACCATGTCCGCCCAGGCGCAGATGCGGGCCCTGCTGGACCAGCTCATGGGCACGGCTCGGGACGGAGACGAA
ACCAGACAGAGGGTCAAGTTTACAGATGACCGTGTCTGCAAGAGTCACCTTCTGGACTGCTGCCCCCATGACATCCTGGCTGGGACGCGC
ATGGATTTAGGAGAATGTACCAAAATCCACGACTTGGCCCTCCGAGCAGATTATGAGATTGCAAGTAAAGAAAGAGACCTGTTTTTTGAA
TTAGATGCAATGGATCACTTGGAGTCCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAG
GAAATCAGTGCGGAAGTTTCTGCAAAGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTA
GGGGCTGAAGGTAATGTGGATGAATCCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGTCTATTCC
TTGGACTCTGCTGACTCTTTCCAAAGCTTCTACAGTCCCCACAAGGCTCAGATGAAGAATCCTATACTGGAGCGCCTGGCAGAGCAGATC
GCGACCCTTTGTGCCACCCTGAAGGAGTACCCGGCTGTGCGGTATCGGGGGGAATACAAGGACAATGCCCTGCTGGCTCAGCTAATCCAG
GACAAGCTCGATGCCTATAAAGCTGATGATCCAACAATGGGGGAGGGCCCAGACAAGGCACGCTCCCAGCTCCTGATCCTGGATCGAGGC
TTTGACCCCAGCTCCCCTGTGCTCCATGAATTGACTTTTCAGGCTATGAGTTATGATCTGCTGCCTATCGAAAATGATGTATACAAGTAT
GAGACCAGCGGCATCGGGGAGGCACGGGTGAAGGAGGTGCTCCTGGACGAGGACGACGACCTGTGGATAGCACTGCGCCACAAGCACATC
GCAGAGGTGTCCCAGGAAGTCACCCGGTCTCTGAAAGATTTTTCTTCTAGCAAGAGAATGAATACTGGAGAGAAGACCACCATGCGGGAC
CTGTCCCAGATGCTGAAGAAGATGCCTCAGTACCAGAAAGAGCTCAGCAAGTACTCCACCCACCTGCACCTTGCTGAGGACTGTATGAAG
CATTACCAAGGCACCGTAGACAAACTCTGCCGAGTGGAGCAGGACCTGGCCATGGGCACAGATGCTGAGGGAGAGAAGATCAAGGACCCT
ATGCGAGCCATCGTCCCCATTCTGCTGGATGCCAATGTCAGCACTTATGACAAAATCCGCATCATCCTTCTCTACATCTTTTTGAAGAAT
GGCATCACGGAGGAAAACCTGAACAAACTGATCCAGCACGCCCAGATACCCCCGGAGGATAGTGAGATCATCACCAACATGGCTCACCTC
GGCGTGCCCATCGTCACCGATTCCACGCTGCGTCGCCGGAGCAAGCCGGAGCGGAAGGAACGCATCAGCGAGCAGACCTACCAGCTCTCA
CGGTGGACTCCGATTATCAAGGACATCATGGAGGACACTATTGAGGACAAACTTGACACCAAACACTACCCTTATATCTCTACCCGTTCC
TCTGCCTCCTTCAGCACCACCGCCGTCAGCGCCCGCTATGGGCACTGGCATAAGAACAAGGCCCCAGGCGAGTACCGCAGTGGCCCCCGC
CTCATCATTTTCATCCTTGGGGGTGTGAGCCTGAATGAGATGCGCTGCGCCTACGAGGTGACCCAGGCCAACGGAAAGTGGGAGGTGCTG
ATAGGTTCTACTCACATTCTTACTCCCACCAAATTTCTCATGGACCTGAGACACCCCGACTTCAGGGAGTCCTCTAGGGTATCTTTTGAG
GATCAGGCTCCAACAATGGAGTGAGAGCCAAAGAAACAAAGATCCACACACATCCTCACCCCACAGAAACTGCTGGACACACTGAAGAAA
CTGAATAAAACAGATGAAGAAATAAGCAGTTAAAAAAATAAGTCGCCCCTCCAAAACACGCCCCCATCCCACAGCGCTCCGCAGCTTCCC
ACCACCGCCCGCCTCAGTTCCTTTGCGTCTGTTGCCTCCCCAGCCCTGCACGCCCTGGCTGGCACTGTTGCCGCTGCATTCTCGTGTTCA
GTGATGCCCTCTTCTTGTTTGAAACAAAAGAAAATAATGCATTGTGTTTTTTAAAAAGAGTATCTTATACATGTATCCTAAAAAGAGAAG
CTCATGTGCAATTGGTGCACAGCAGGAGAAATTTCTGGACTGTTAGGATGAATGGACGCCTTCTCCCCGTTATTTAAGATTTGTGACCTT
GTACATAACCCTGGGTGACGTGCACATTGCTTGGGTATGGAACGGTAGAAATTTGGGTGTTTTTAAAACCTTGTTTGGGGTTGTTCCTGT
CCTTGTTGAGAATCATAGAGATGTCTGTGTTCTTGGAGTATTTCACACTGAGGACTAATCTGCTATCTTCATTCCAGTCCCTACCCCTCA
GTGCCTGCTCTCATCCAAATAACCTGGGAGGTGACAATCAGGATATCTCAGGAGGTCCAAGGTGGAACAGACCTCTTTGCCTTTCCCAGC
GTCTCATACCCCCGGTAGTGCAGCTGTGGGTGGAGGCTGGGGTGTCTGCACGAAGTCAGGCCAGCGTCCTCCTCCACAGCCTGTCACTGC
CCCCTCCCCAGCCTGTGTCCACAGTGCTGTGATCCCGAGGGAAGTCCTCCAGTCTAAGTCACAGTGCCCTGACAGGTGAGAAGCAAACTC
CCGCTGGAAGCCTCCATCTCTTTGGAAAAACAGTTAGTCTGGAGCCTGTGGCCCAGGCCCTTCTGTCCCCAGGCATCATCCCAACAGCTC
ATTTTCCCTAGTCCGCCTTCGTTCAAGGGTCAGGAATGGACCAGAACAGATGGGTTCTGGAGGCCCCTGAACAGAGGGCTATGGCTGTGG
AGAAGGTTCTTGGCCCGTTGGACTCACACAGACCCTGTACCCTCTCGGCAAGCATCTTCAGTCAGATTATCCTCAGTTTCAGATACTTCA
TAATACCTTGTGTTGTGTGGGGTCATACATCATCGTGTTTGTAAGAGAAGATGGTCATTTTATTCTCTGTATAAAACTTAGCTCTAAAGC
AGAAACTAAAGCAGCAAATGCAGGAAGGCTGTCTCGCCATCCTCAAGACTCAGCAGCTCTCATTCTCCAGTGGTGAGCACACCATTTGTG
CTGCTGCTGTTGTCGTGAAATATAATAACAGTGGAAGTCACAAAAATGTCCCCTGCCCAGCCCCCTCGCCGCCCTTGACCTCCTGCAGGC
CATGTGTGTATTACTTGTCTAGTGATGTCCTCTCAAAGTGCTGTACGCGAGCTCGGCGCCACCTCCGCCTCCCTTTCAGAGCCTGCTCCC
CGCCCTCTCTGCTCGCTGCATTGTGGTGTTCTCTTCTCAAGGCTTTGAAATCTCCCCTTGCACTGAGATTAGTCGTCAGATCTCTCCCCG
TCTCCCTCCCAACTTATACGACCTGATTTCCTTAGGACGGAACCGCAGGCACCTGCGCCGGGCGTCTTACTCCCGCTGCTTGTTCTGTCC
CCTCCCTCGGACCAAACAGTGCTCATGCTTCAGGACCTTGTTTGTCGAAGATGTTGGTTTCCCTTTCTCTGTTATTTATATAAAAATAAT
TTATCAAAAGGATATTTTAAAAAAGCTAGTCTGTCTTGAAACTTGTTTACCTTAAAATTATCAGAATCTCAGTGTTTGAAAGTACTGAAG
CACAAACATATATCATCTCTGTACCATTCTGTACTAAAGCACTTGAGTCTAATAAATAAAGAAATCAGCACCCCTTCCCGGTGTCCAGGG

>50376_50376_2_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000293872_STXBP1_chr9_130425484_ENST00000373302_length(amino acids)=630AA_BP=170
MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHL
ESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEVYSLDSADSF
QSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPV
LHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKK
MPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENL
NKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTT
AVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPDFRESSRVSFEDQAPTME

--------------------------------------------------------------
>50376_50376_3_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000337351_STXBP1_chr9_130425484_ENST00000373299_length(transcript)=3849nt_BP=634nt
TCCCCCGCGGCGGGAAAGAGCCGAGTGGGCTCGAGGCCGACGCGACCATCGTTTGTCGACGCCGCTGCCACCGCCTGCCTGAGAGAAGTC
GTCGCGGCCGACCCCGTCGCCTCCGCCGGCTACCATGTCCGCCCAGGCGCAGATGCGGGCCCTGCTGGACCAGCTCATGGGCACGGCTCG
GGACGGAGACGAAACCAGACAGAGGGTCAAGTTTACAGATGACCGTGTCTGCAAGAGTCACCTTCTGGACTGCTGCCCCCATGACATCCT
GGCTGGGACGCGCATGGATTTAGGAGAATGTACCAAAATCCACGACTTGGCCCTCCGAGCAGATTATGAGATTGCAAGTAAAGAAAGAGA
CCTGTTTTTTGAATTAGATGCAATGGATCACTTGGAGTCCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGC
AGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAAAGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAA
AGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAATCCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGC
TGAGGTCTATTCCTTGGACTCTGCTGACTCTTTCCAAAGCTTCTACAGTCCCCACAAGGCTCAGATGAAGAATCCTATACTGGAGCGCCT
GGCAGAGCAGATCGCGACCCTTTGTGCCACCCTGAAGGAGTACCCGGCTGTGCGGTATCGGGGGGAATACAAGGACAATGCCCTGCTGGC
TCAGCTAATCCAGGACAAGCTCGATGCCTATAAAGCTGATGATCCAACAATGGGGGAGGGCCCAGACAAGGCACGCTCCCAGCTCCTGAT
CCTGGATCGAGGCTTTGACCCCAGCTCCCCTGTGCTCCATGAATTGACTTTTCAGGCTATGAGTTATGATCTGCTGCCTATCGAAAATGA
TGTATACAAGTATGAGACCAGCGGCATCGGGGAGGCACGGGTGAAGGAGGTGCTCCTGGACGAGGACGACGACCTGTGGATAGCACTGCG
CCACAAGCACATCGCAGAGGTGTCCCAGGAAGTCACCCGGTCTCTGAAAGATTTTTCTTCTAGCAAGAGAATGAATACTGGAGAGAAGAC
CACCATGCGGGACCTGTCCCAGATGCTGAAGAAGATGCCTCAGTACCAGAAAGAGCTCAGCAAGTACTCCACCCACCTGCACCTTGCTGA
GGACTGTATGAAGCATTACCAAGGCACCGTAGACAAACTCTGCCGAGTGGAGCAGGACCTGGCCATGGGCACAGATGCTGAGGGAGAGAA
GATCAAGGACCCTATGCGAGCCATCGTCCCCATTCTGCTGGATGCCAATGTCAGCACTTATGACAAAATCCGCATCATCCTTCTCTACAT
CTTTTTGAAGAATGGCATCACGGAGGAAAACCTGAACAAACTGATCCAGCACGCCCAGATACCCCCGGAGGATAGTGAGATCATCACCAA
CATGGCTCACCTCGGCGTGCCCATCGTCACCGATTCCACGCTGCGTCGCCGGAGCAAGCCGGAGCGGAAGGAACGCATCAGCGAGCAGAC
CTACCAGCTCTCACGGTGGACTCCGATTATCAAGGACATCATGGAGGACACTATTGAGGACAAACTTGACACCAAACACTACCCTTATAT
CTCTACCCGTTCCTCTGCCTCCTTCAGCACCACCGCCGTCAGCGCCCGCTATGGGCACTGGCATAAGAACAAGGCCCCAGGCGAGTACCG
CAGTGGCCCCCGCCTCATCATTTTCATCCTTGGGGGTGTGAGCCTGAATGAGATGCGCTGCGCCTACGAGGTGACCCAGGCCAACGGAAA
GTGGGAGGTGCTGATAGGATCCACACACATCCTCACCCCACAGAAACTGCTGGACACACTGAAGAAACTGAATAAAACAGATGAAGAAAT
AAGCAGTTAAAAAAATAAGTCGCCCCTCCAAAACACGCCCCCATCCCACAGCGCTCCGCAGCTTCCCACCACCGCCCGCCTCAGTTCCTT
TGCGTCTGTTGCCTCCCCAGCCCTGCACGCCCTGGCTGGCACTGTTGCCGCTGCATTCTCGTGTTCAGTGATGCCCTCTTCTTGTTTGAA
ACAAAAGAAAATAATGCATTGTGTTTTTTAAAAAGAGTATCTTATACATGTATCCTAAAAAGAGAAGCTCATGTGCAATTGGTGCACAGC
AGGAGAAATTTCTGGACTGTTAGGATGAATGGACGCCTTCTCCCCGTTATTTAAGATTTGTGACCTTGTACATAACCCTGGGTGACGTGC
ACATTGCTTGGGTATGGAACGGTAGAAATTTGGGTGTTTTTAAAACCTTGTTTGGGGTTGTTCCTGTCCTTGTTGAGAATCATAGAGATG
TCTGTGTTCTTGGAGTATTTCACACTGAGGACTAATCTGCTATCTTCATTCCAGTCCCTACCCCTCAGTGCCTGCTCTCATCCAAATAAC
CTGGGAGGTGACAATCAGGATATCTCAGGAGGTCCAAGGTGGAACAGACCTCTTTGCCTTTCCCAGCGTCTCATACCCCCGGTAGTGCAG
CTGTGGGTGGAGGCTGGGGTGTCTGCACGAAGTCAGGCCAGCGTCCTCCTCCACAGCCTGTCACTGCCCCCTCCCCAGCCTGTGTCCACA
GTGCTGTGATCCCGAGGGAAGTCCTCCAGTCTAAGTCACAGTGCCCTGACAGGTGAGAAGCAAACTCCCGCTGGAAGCCTCCATCTCTTT
GGAAAAACAGTTAGTCTGGAGCCTGTGGCCCAGGCCCTTCTGTCCCCAGGCATCATCCCAACAGCTCATTTTCCCTAGTCCGCCTTCGTT
CAAGGGTCAGGAATGGACCAGAACAGATGGGTTCTGGAGGCCCCTGAACAGAGGGCTATGGCTGTGGAGAAGGTTCTTGGCCCGTTGGAC
TCACACAGACCCTGTACCCTCTCGGCAAGCATCTTCAGTCAGATTATCCTCAGTTTCAGATACTTCATAATACCTTGTGTTGTGTGGGGT
CATACATCATCGTGTTTGTAAGAGAAGATGGTCATTTTATTCTCTGTATAAAACTTAGCTCTAAAGCAGAAACTAAAGCAGCAAATGCAG
GAAGGCTGTCTCGCCATCCTCAAGACTCAGCAGCTCTCATTCTCCAGTGGTGAGCACACCATTTGTGCTGCTGCTGTTGTCGTGAAATAT
AATAACAGTGGAAGTCACAAAAATGTCCCCTGCCCAGCCCCCTCGCCGCCCTTGACCTCCTGCAGGCCATGTGTGTATTACTTGTCTAGT
GATGTCCTCTCAAAGTGCTGTACGCGAGCTCGGCGCCACCTCCGCCTCCCTTTCAGAGCCTGCTCCCCGCCCTCTCTGCTCGCTGCATTG
TGGTGTTCTCTTCTCAAGGCTTTGAAATCTCCCCTTGCACTGAGATTAGTCGTCAGATCTCTCCCCGTCTCCCTCCCAACTTATACGACC
TGATTTCCTTAGGACGGAACCGCAGGCACCTGCGCCGGGCGTCTTACTCCCGCTGCTTGTTCTGTCCCCTCCCTCGGACCAAACAGTGCT
CATGCTTCAGGACCTTGTTTGTCGAAGATGTTGGTTTCCCTTTCTCTGTTATTTATATAAAAATAATTTATCAAAAGGATATTTTAAAAA
AGCTAGTCTGTCTTGAAACTTGTTTACCTTAAAATTATCAGAATCTCAGTGTTTGAAAGTACTGAAGCACAAACATATATCATCTCTGTA

>50376_50376_3_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000337351_STXBP1_chr9_130425484_ENST00000373299_length(amino acids)=621AA_BP=170
MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHL
ESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEVYSLDSADSF
QSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPV
LHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKK
MPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENL
NKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTT

--------------------------------------------------------------
>50376_50376_4_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000337351_STXBP1_chr9_130425484_ENST00000373302_length(transcript)=3975nt_BP=634nt
TCCCCCGCGGCGGGAAAGAGCCGAGTGGGCTCGAGGCCGACGCGACCATCGTTTGTCGACGCCGCTGCCACCGCCTGCCTGAGAGAAGTC
GTCGCGGCCGACCCCGTCGCCTCCGCCGGCTACCATGTCCGCCCAGGCGCAGATGCGGGCCCTGCTGGACCAGCTCATGGGCACGGCTCG
GGACGGAGACGAAACCAGACAGAGGGTCAAGTTTACAGATGACCGTGTCTGCAAGAGTCACCTTCTGGACTGCTGCCCCCATGACATCCT
GGCTGGGACGCGCATGGATTTAGGAGAATGTACCAAAATCCACGACTTGGCCCTCCGAGCAGATTATGAGATTGCAAGTAAAGAAAGAGA
CCTGTTTTTTGAATTAGATGCAATGGATCACTTGGAGTCCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGC
AGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAAAGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAA
AGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAATCCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGC
TGAGGTCTATTCCTTGGACTCTGCTGACTCTTTCCAAAGCTTCTACAGTCCCCACAAGGCTCAGATGAAGAATCCTATACTGGAGCGCCT
GGCAGAGCAGATCGCGACCCTTTGTGCCACCCTGAAGGAGTACCCGGCTGTGCGGTATCGGGGGGAATACAAGGACAATGCCCTGCTGGC
TCAGCTAATCCAGGACAAGCTCGATGCCTATAAAGCTGATGATCCAACAATGGGGGAGGGCCCAGACAAGGCACGCTCCCAGCTCCTGAT
CCTGGATCGAGGCTTTGACCCCAGCTCCCCTGTGCTCCATGAATTGACTTTTCAGGCTATGAGTTATGATCTGCTGCCTATCGAAAATGA
TGTATACAAGTATGAGACCAGCGGCATCGGGGAGGCACGGGTGAAGGAGGTGCTCCTGGACGAGGACGACGACCTGTGGATAGCACTGCG
CCACAAGCACATCGCAGAGGTGTCCCAGGAAGTCACCCGGTCTCTGAAAGATTTTTCTTCTAGCAAGAGAATGAATACTGGAGAGAAGAC
CACCATGCGGGACCTGTCCCAGATGCTGAAGAAGATGCCTCAGTACCAGAAAGAGCTCAGCAAGTACTCCACCCACCTGCACCTTGCTGA
GGACTGTATGAAGCATTACCAAGGCACCGTAGACAAACTCTGCCGAGTGGAGCAGGACCTGGCCATGGGCACAGATGCTGAGGGAGAGAA
GATCAAGGACCCTATGCGAGCCATCGTCCCCATTCTGCTGGATGCCAATGTCAGCACTTATGACAAAATCCGCATCATCCTTCTCTACAT
CTTTTTGAAGAATGGCATCACGGAGGAAAACCTGAACAAACTGATCCAGCACGCCCAGATACCCCCGGAGGATAGTGAGATCATCACCAA
CATGGCTCACCTCGGCGTGCCCATCGTCACCGATTCCACGCTGCGTCGCCGGAGCAAGCCGGAGCGGAAGGAACGCATCAGCGAGCAGAC
CTACCAGCTCTCACGGTGGACTCCGATTATCAAGGACATCATGGAGGACACTATTGAGGACAAACTTGACACCAAACACTACCCTTATAT
CTCTACCCGTTCCTCTGCCTCCTTCAGCACCACCGCCGTCAGCGCCCGCTATGGGCACTGGCATAAGAACAAGGCCCCAGGCGAGTACCG
CAGTGGCCCCCGCCTCATCATTTTCATCCTTGGGGGTGTGAGCCTGAATGAGATGCGCTGCGCCTACGAGGTGACCCAGGCCAACGGAAA
GTGGGAGGTGCTGATAGGTTCTACTCACATTCTTACTCCCACCAAATTTCTCATGGACCTGAGACACCCCGACTTCAGGGAGTCCTCTAG
GGTATCTTTTGAGGATCAGGCTCCAACAATGGAGTGAGAGCCAAAGAAACAAAGATCCACACACATCCTCACCCCACAGAAACTGCTGGA
CACACTGAAGAAACTGAATAAAACAGATGAAGAAATAAGCAGTTAAAAAAATAAGTCGCCCCTCCAAAACACGCCCCCATCCCACAGCGC
TCCGCAGCTTCCCACCACCGCCCGCCTCAGTTCCTTTGCGTCTGTTGCCTCCCCAGCCCTGCACGCCCTGGCTGGCACTGTTGCCGCTGC
ATTCTCGTGTTCAGTGATGCCCTCTTCTTGTTTGAAACAAAAGAAAATAATGCATTGTGTTTTTTAAAAAGAGTATCTTATACATGTATC
CTAAAAAGAGAAGCTCATGTGCAATTGGTGCACAGCAGGAGAAATTTCTGGACTGTTAGGATGAATGGACGCCTTCTCCCCGTTATTTAA
GATTTGTGACCTTGTACATAACCCTGGGTGACGTGCACATTGCTTGGGTATGGAACGGTAGAAATTTGGGTGTTTTTAAAACCTTGTTTG
GGGTTGTTCCTGTCCTTGTTGAGAATCATAGAGATGTCTGTGTTCTTGGAGTATTTCACACTGAGGACTAATCTGCTATCTTCATTCCAG
TCCCTACCCCTCAGTGCCTGCTCTCATCCAAATAACCTGGGAGGTGACAATCAGGATATCTCAGGAGGTCCAAGGTGGAACAGACCTCTT
TGCCTTTCCCAGCGTCTCATACCCCCGGTAGTGCAGCTGTGGGTGGAGGCTGGGGTGTCTGCACGAAGTCAGGCCAGCGTCCTCCTCCAC
AGCCTGTCACTGCCCCCTCCCCAGCCTGTGTCCACAGTGCTGTGATCCCGAGGGAAGTCCTCCAGTCTAAGTCACAGTGCCCTGACAGGT
GAGAAGCAAACTCCCGCTGGAAGCCTCCATCTCTTTGGAAAAACAGTTAGTCTGGAGCCTGTGGCCCAGGCCCTTCTGTCCCCAGGCATC
ATCCCAACAGCTCATTTTCCCTAGTCCGCCTTCGTTCAAGGGTCAGGAATGGACCAGAACAGATGGGTTCTGGAGGCCCCTGAACAGAGG
GCTATGGCTGTGGAGAAGGTTCTTGGCCCGTTGGACTCACACAGACCCTGTACCCTCTCGGCAAGCATCTTCAGTCAGATTATCCTCAGT
TTCAGATACTTCATAATACCTTGTGTTGTGTGGGGTCATACATCATCGTGTTTGTAAGAGAAGATGGTCATTTTATTCTCTGTATAAAAC
TTAGCTCTAAAGCAGAAACTAAAGCAGCAAATGCAGGAAGGCTGTCTCGCCATCCTCAAGACTCAGCAGCTCTCATTCTCCAGTGGTGAG
CACACCATTTGTGCTGCTGCTGTTGTCGTGAAATATAATAACAGTGGAAGTCACAAAAATGTCCCCTGCCCAGCCCCCTCGCCGCCCTTG
ACCTCCTGCAGGCCATGTGTGTATTACTTGTCTAGTGATGTCCTCTCAAAGTGCTGTACGCGAGCTCGGCGCCACCTCCGCCTCCCTTTC
AGAGCCTGCTCCCCGCCCTCTCTGCTCGCTGCATTGTGGTGTTCTCTTCTCAAGGCTTTGAAATCTCCCCTTGCACTGAGATTAGTCGTC
AGATCTCTCCCCGTCTCCCTCCCAACTTATACGACCTGATTTCCTTAGGACGGAACCGCAGGCACCTGCGCCGGGCGTCTTACTCCCGCT
GCTTGTTCTGTCCCCTCCCTCGGACCAAACAGTGCTCATGCTTCAGGACCTTGTTTGTCGAAGATGTTGGTTTCCCTTTCTCTGTTATTT
ATATAAAAATAATTTATCAAAAGGATATTTTAAAAAAGCTAGTCTGTCTTGAAACTTGTTTACCTTAAAATTATCAGAATCTCAGTGTTT
GAAAGTACTGAAGCACAAACATATATCATCTCTGTACCATTCTGTACTAAAGCACTTGAGTCTAATAAATAAAGAAATCAGCACCCCTTC

>50376_50376_4_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000337351_STXBP1_chr9_130425484_ENST00000373302_length(amino acids)=630AA_BP=170
MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHL
ESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEVYSLDSADSF
QSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPV
LHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKK
MPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENL
NKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTT
AVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPDFRESSRVSFEDQAPTME

--------------------------------------------------------------
>50376_50376_5_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000397783_STXBP1_chr9_130425484_ENST00000373299_length(transcript)=3849nt_BP=634nt
TCCCCCGCGGCGGGAAAGAGCCGAGTGGGCTCGAGGCCGACGCGACCATCGTTTGTCGACGCCGCTGCCACCGCCTGCCTGAGAGAAGTC
GTCGCGGCCGACCCCGTCGCCTCCGCCGGCTACCATGTCCGCCCAGGCGCAGATGCGGGCCCTGCTGGACCAGCTCATGGGCACGGCTCG
GGACGGAGACGAAACCAGACAGAGGGTCAAGTTTACAGATGACCGTGTCTGCAAGAGTCACCTTCTGGACTGCTGCCCCCATGACATCCT
GGCTGGGACGCGCATGGATTTAGGAGAATGTACCAAAATCCACGACTTGGCCCTCCGAGCAGATTATGAGATTGCAAGTAAAGAAAGAGA
CCTGTTTTTTGAATTAGATGCAATGGATCACTTGGAGTCCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGC
AGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAAAGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAA
AGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAATCCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGC
TGAGGTCTATTCCTTGGACTCTGCTGACTCTTTCCAAAGCTTCTACAGTCCCCACAAGGCTCAGATGAAGAATCCTATACTGGAGCGCCT
GGCAGAGCAGATCGCGACCCTTTGTGCCACCCTGAAGGAGTACCCGGCTGTGCGGTATCGGGGGGAATACAAGGACAATGCCCTGCTGGC
TCAGCTAATCCAGGACAAGCTCGATGCCTATAAAGCTGATGATCCAACAATGGGGGAGGGCCCAGACAAGGCACGCTCCCAGCTCCTGAT
CCTGGATCGAGGCTTTGACCCCAGCTCCCCTGTGCTCCATGAATTGACTTTTCAGGCTATGAGTTATGATCTGCTGCCTATCGAAAATGA
TGTATACAAGTATGAGACCAGCGGCATCGGGGAGGCACGGGTGAAGGAGGTGCTCCTGGACGAGGACGACGACCTGTGGATAGCACTGCG
CCACAAGCACATCGCAGAGGTGTCCCAGGAAGTCACCCGGTCTCTGAAAGATTTTTCTTCTAGCAAGAGAATGAATACTGGAGAGAAGAC
CACCATGCGGGACCTGTCCCAGATGCTGAAGAAGATGCCTCAGTACCAGAAAGAGCTCAGCAAGTACTCCACCCACCTGCACCTTGCTGA
GGACTGTATGAAGCATTACCAAGGCACCGTAGACAAACTCTGCCGAGTGGAGCAGGACCTGGCCATGGGCACAGATGCTGAGGGAGAGAA
GATCAAGGACCCTATGCGAGCCATCGTCCCCATTCTGCTGGATGCCAATGTCAGCACTTATGACAAAATCCGCATCATCCTTCTCTACAT
CTTTTTGAAGAATGGCATCACGGAGGAAAACCTGAACAAACTGATCCAGCACGCCCAGATACCCCCGGAGGATAGTGAGATCATCACCAA
CATGGCTCACCTCGGCGTGCCCATCGTCACCGATTCCACGCTGCGTCGCCGGAGCAAGCCGGAGCGGAAGGAACGCATCAGCGAGCAGAC
CTACCAGCTCTCACGGTGGACTCCGATTATCAAGGACATCATGGAGGACACTATTGAGGACAAACTTGACACCAAACACTACCCTTATAT
CTCTACCCGTTCCTCTGCCTCCTTCAGCACCACCGCCGTCAGCGCCCGCTATGGGCACTGGCATAAGAACAAGGCCCCAGGCGAGTACCG
CAGTGGCCCCCGCCTCATCATTTTCATCCTTGGGGGTGTGAGCCTGAATGAGATGCGCTGCGCCTACGAGGTGACCCAGGCCAACGGAAA
GTGGGAGGTGCTGATAGGATCCACACACATCCTCACCCCACAGAAACTGCTGGACACACTGAAGAAACTGAATAAAACAGATGAAGAAAT
AAGCAGTTAAAAAAATAAGTCGCCCCTCCAAAACACGCCCCCATCCCACAGCGCTCCGCAGCTTCCCACCACCGCCCGCCTCAGTTCCTT
TGCGTCTGTTGCCTCCCCAGCCCTGCACGCCCTGGCTGGCACTGTTGCCGCTGCATTCTCGTGTTCAGTGATGCCCTCTTCTTGTTTGAA
ACAAAAGAAAATAATGCATTGTGTTTTTTAAAAAGAGTATCTTATACATGTATCCTAAAAAGAGAAGCTCATGTGCAATTGGTGCACAGC
AGGAGAAATTTCTGGACTGTTAGGATGAATGGACGCCTTCTCCCCGTTATTTAAGATTTGTGACCTTGTACATAACCCTGGGTGACGTGC
ACATTGCTTGGGTATGGAACGGTAGAAATTTGGGTGTTTTTAAAACCTTGTTTGGGGTTGTTCCTGTCCTTGTTGAGAATCATAGAGATG
TCTGTGTTCTTGGAGTATTTCACACTGAGGACTAATCTGCTATCTTCATTCCAGTCCCTACCCCTCAGTGCCTGCTCTCATCCAAATAAC
CTGGGAGGTGACAATCAGGATATCTCAGGAGGTCCAAGGTGGAACAGACCTCTTTGCCTTTCCCAGCGTCTCATACCCCCGGTAGTGCAG
CTGTGGGTGGAGGCTGGGGTGTCTGCACGAAGTCAGGCCAGCGTCCTCCTCCACAGCCTGTCACTGCCCCCTCCCCAGCCTGTGTCCACA
GTGCTGTGATCCCGAGGGAAGTCCTCCAGTCTAAGTCACAGTGCCCTGACAGGTGAGAAGCAAACTCCCGCTGGAAGCCTCCATCTCTTT
GGAAAAACAGTTAGTCTGGAGCCTGTGGCCCAGGCCCTTCTGTCCCCAGGCATCATCCCAACAGCTCATTTTCCCTAGTCCGCCTTCGTT
CAAGGGTCAGGAATGGACCAGAACAGATGGGTTCTGGAGGCCCCTGAACAGAGGGCTATGGCTGTGGAGAAGGTTCTTGGCCCGTTGGAC
TCACACAGACCCTGTACCCTCTCGGCAAGCATCTTCAGTCAGATTATCCTCAGTTTCAGATACTTCATAATACCTTGTGTTGTGTGGGGT
CATACATCATCGTGTTTGTAAGAGAAGATGGTCATTTTATTCTCTGTATAAAACTTAGCTCTAAAGCAGAAACTAAAGCAGCAAATGCAG
GAAGGCTGTCTCGCCATCCTCAAGACTCAGCAGCTCTCATTCTCCAGTGGTGAGCACACCATTTGTGCTGCTGCTGTTGTCGTGAAATAT
AATAACAGTGGAAGTCACAAAAATGTCCCCTGCCCAGCCCCCTCGCCGCCCTTGACCTCCTGCAGGCCATGTGTGTATTACTTGTCTAGT
GATGTCCTCTCAAAGTGCTGTACGCGAGCTCGGCGCCACCTCCGCCTCCCTTTCAGAGCCTGCTCCCCGCCCTCTCTGCTCGCTGCATTG
TGGTGTTCTCTTCTCAAGGCTTTGAAATCTCCCCTTGCACTGAGATTAGTCGTCAGATCTCTCCCCGTCTCCCTCCCAACTTATACGACC
TGATTTCCTTAGGACGGAACCGCAGGCACCTGCGCCGGGCGTCTTACTCCCGCTGCTTGTTCTGTCCCCTCCCTCGGACCAAACAGTGCT
CATGCTTCAGGACCTTGTTTGTCGAAGATGTTGGTTTCCCTTTCTCTGTTATTTATATAAAAATAATTTATCAAAAGGATATTTTAAAAA
AGCTAGTCTGTCTTGAAACTTGTTTACCTTAAAATTATCAGAATCTCAGTGTTTGAAAGTACTGAAGCACAAACATATATCATCTCTGTA

>50376_50376_5_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000397783_STXBP1_chr9_130425484_ENST00000373299_length(amino acids)=621AA_BP=170
MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHL
ESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEVYSLDSADSF
QSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPV
LHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKK
MPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENL
NKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTT

--------------------------------------------------------------
>50376_50376_6_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000397783_STXBP1_chr9_130425484_ENST00000373302_length(transcript)=3975nt_BP=634nt
TCCCCCGCGGCGGGAAAGAGCCGAGTGGGCTCGAGGCCGACGCGACCATCGTTTGTCGACGCCGCTGCCACCGCCTGCCTGAGAGAAGTC
GTCGCGGCCGACCCCGTCGCCTCCGCCGGCTACCATGTCCGCCCAGGCGCAGATGCGGGCCCTGCTGGACCAGCTCATGGGCACGGCTCG
GGACGGAGACGAAACCAGACAGAGGGTCAAGTTTACAGATGACCGTGTCTGCAAGAGTCACCTTCTGGACTGCTGCCCCCATGACATCCT
GGCTGGGACGCGCATGGATTTAGGAGAATGTACCAAAATCCACGACTTGGCCCTCCGAGCAGATTATGAGATTGCAAGTAAAGAAAGAGA
CCTGTTTTTTGAATTAGATGCAATGGATCACTTGGAGTCCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGC
AGAAACACAGGAGGAAATCAGTGCGGAAGTTTCTGCAAAGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAA
AGCCGAACAGCTAGGGGCTGAAGGTAATGTGGATGAATCCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGC
TGAGGTCTATTCCTTGGACTCTGCTGACTCTTTCCAAAGCTTCTACAGTCCCCACAAGGCTCAGATGAAGAATCCTATACTGGAGCGCCT
GGCAGAGCAGATCGCGACCCTTTGTGCCACCCTGAAGGAGTACCCGGCTGTGCGGTATCGGGGGGAATACAAGGACAATGCCCTGCTGGC
TCAGCTAATCCAGGACAAGCTCGATGCCTATAAAGCTGATGATCCAACAATGGGGGAGGGCCCAGACAAGGCACGCTCCCAGCTCCTGAT
CCTGGATCGAGGCTTTGACCCCAGCTCCCCTGTGCTCCATGAATTGACTTTTCAGGCTATGAGTTATGATCTGCTGCCTATCGAAAATGA
TGTATACAAGTATGAGACCAGCGGCATCGGGGAGGCACGGGTGAAGGAGGTGCTCCTGGACGAGGACGACGACCTGTGGATAGCACTGCG
CCACAAGCACATCGCAGAGGTGTCCCAGGAAGTCACCCGGTCTCTGAAAGATTTTTCTTCTAGCAAGAGAATGAATACTGGAGAGAAGAC
CACCATGCGGGACCTGTCCCAGATGCTGAAGAAGATGCCTCAGTACCAGAAAGAGCTCAGCAAGTACTCCACCCACCTGCACCTTGCTGA
GGACTGTATGAAGCATTACCAAGGCACCGTAGACAAACTCTGCCGAGTGGAGCAGGACCTGGCCATGGGCACAGATGCTGAGGGAGAGAA
GATCAAGGACCCTATGCGAGCCATCGTCCCCATTCTGCTGGATGCCAATGTCAGCACTTATGACAAAATCCGCATCATCCTTCTCTACAT
CTTTTTGAAGAATGGCATCACGGAGGAAAACCTGAACAAACTGATCCAGCACGCCCAGATACCCCCGGAGGATAGTGAGATCATCACCAA
CATGGCTCACCTCGGCGTGCCCATCGTCACCGATTCCACGCTGCGTCGCCGGAGCAAGCCGGAGCGGAAGGAACGCATCAGCGAGCAGAC
CTACCAGCTCTCACGGTGGACTCCGATTATCAAGGACATCATGGAGGACACTATTGAGGACAAACTTGACACCAAACACTACCCTTATAT
CTCTACCCGTTCCTCTGCCTCCTTCAGCACCACCGCCGTCAGCGCCCGCTATGGGCACTGGCATAAGAACAAGGCCCCAGGCGAGTACCG
CAGTGGCCCCCGCCTCATCATTTTCATCCTTGGGGGTGTGAGCCTGAATGAGATGCGCTGCGCCTACGAGGTGACCCAGGCCAACGGAAA
GTGGGAGGTGCTGATAGGTTCTACTCACATTCTTACTCCCACCAAATTTCTCATGGACCTGAGACACCCCGACTTCAGGGAGTCCTCTAG
GGTATCTTTTGAGGATCAGGCTCCAACAATGGAGTGAGAGCCAAAGAAACAAAGATCCACACACATCCTCACCCCACAGAAACTGCTGGA
CACACTGAAGAAACTGAATAAAACAGATGAAGAAATAAGCAGTTAAAAAAATAAGTCGCCCCTCCAAAACACGCCCCCATCCCACAGCGC
TCCGCAGCTTCCCACCACCGCCCGCCTCAGTTCCTTTGCGTCTGTTGCCTCCCCAGCCCTGCACGCCCTGGCTGGCACTGTTGCCGCTGC
ATTCTCGTGTTCAGTGATGCCCTCTTCTTGTTTGAAACAAAAGAAAATAATGCATTGTGTTTTTTAAAAAGAGTATCTTATACATGTATC
CTAAAAAGAGAAGCTCATGTGCAATTGGTGCACAGCAGGAGAAATTTCTGGACTGTTAGGATGAATGGACGCCTTCTCCCCGTTATTTAA
GATTTGTGACCTTGTACATAACCCTGGGTGACGTGCACATTGCTTGGGTATGGAACGGTAGAAATTTGGGTGTTTTTAAAACCTTGTTTG
GGGTTGTTCCTGTCCTTGTTGAGAATCATAGAGATGTCTGTGTTCTTGGAGTATTTCACACTGAGGACTAATCTGCTATCTTCATTCCAG
TCCCTACCCCTCAGTGCCTGCTCTCATCCAAATAACCTGGGAGGTGACAATCAGGATATCTCAGGAGGTCCAAGGTGGAACAGACCTCTT
TGCCTTTCCCAGCGTCTCATACCCCCGGTAGTGCAGCTGTGGGTGGAGGCTGGGGTGTCTGCACGAAGTCAGGCCAGCGTCCTCCTCCAC
AGCCTGTCACTGCCCCCTCCCCAGCCTGTGTCCACAGTGCTGTGATCCCGAGGGAAGTCCTCCAGTCTAAGTCACAGTGCCCTGACAGGT
GAGAAGCAAACTCCCGCTGGAAGCCTCCATCTCTTTGGAAAAACAGTTAGTCTGGAGCCTGTGGCCCAGGCCCTTCTGTCCCCAGGCATC
ATCCCAACAGCTCATTTTCCCTAGTCCGCCTTCGTTCAAGGGTCAGGAATGGACCAGAACAGATGGGTTCTGGAGGCCCCTGAACAGAGG
GCTATGGCTGTGGAGAAGGTTCTTGGCCCGTTGGACTCACACAGACCCTGTACCCTCTCGGCAAGCATCTTCAGTCAGATTATCCTCAGT
TTCAGATACTTCATAATACCTTGTGTTGTGTGGGGTCATACATCATCGTGTTTGTAAGAGAAGATGGTCATTTTATTCTCTGTATAAAAC
TTAGCTCTAAAGCAGAAACTAAAGCAGCAAATGCAGGAAGGCTGTCTCGCCATCCTCAAGACTCAGCAGCTCTCATTCTCCAGTGGTGAG
CACACCATTTGTGCTGCTGCTGTTGTCGTGAAATATAATAACAGTGGAAGTCACAAAAATGTCCCCTGCCCAGCCCCCTCGCCGCCCTTG
ACCTCCTGCAGGCCATGTGTGTATTACTTGTCTAGTGATGTCCTCTCAAAGTGCTGTACGCGAGCTCGGCGCCACCTCCGCCTCCCTTTC
AGAGCCTGCTCCCCGCCCTCTCTGCTCGCTGCATTGTGGTGTTCTCTTCTCAAGGCTTTGAAATCTCCCCTTGCACTGAGATTAGTCGTC
AGATCTCTCCCCGTCTCCCTCCCAACTTATACGACCTGATTTCCTTAGGACGGAACCGCAGGCACCTGCGCCGGGCGTCTTACTCCCGCT
GCTTGTTCTGTCCCCTCCCTCGGACCAAACAGTGCTCATGCTTCAGGACCTTGTTTGTCGAAGATGTTGGTTTCCCTTTCTCTGTTATTT
ATATAAAAATAATTTATCAAAAGGATATTTTAAAAAAGCTAGTCTGTCTTGAAACTTGTTTACCTTAAAATTATCAGAATCTCAGTGTTT
GAAAGTACTGAAGCACAAACATATATCATCTCTGTACCATTCTGTACTAAAGCACTTGAGTCTAATAAATAAAGAAATCAGCACCCCTTC

>50376_50376_6_LUC7L-STXBP1_LUC7L_chr16_256003_ENST00000397783_STXBP1_chr9_130425484_ENST00000373302_length(amino acids)=630AA_BP=170
MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHL
ESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEVYSLDSADSF
QSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYRGEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPV
LHELTFQAMSYDLLPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGEKTTMRDLSQMLKK
MPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIKDPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENL
NKLIQHAQIPPEDSEIITNMAHLGVPIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFSTT
AVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPTKFLMDLRHPDFRESSRVSFEDQAPTME

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Fusion Gene PPI Analysis for LUC7L-STXBP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LUC7L-STXBP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LUC7L-STXBP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource