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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANXA2-SMG1 (FusionGDB2 ID:5042)

Fusion Gene Summary for ANXA2-SMG1

check button Fusion gene summary
Fusion gene informationFusion gene name: ANXA2-SMG1
Fusion gene ID: 5042
HgeneTgene
Gene symbol

ANXA2

SMG1

Gene ID

302

23049

Gene nameannexin A2SMG1 nonsense mediated mRNA decay associated PI3K related kinase
SynonymsANX2|ANX2L4|CAL1H|HEL-S-270|LIP2|LPC2|LPC2D|P36|PAP-IV61E3.4|ATX|LIP
Cytomap

15q22.2

16p12.3

Type of geneprotein-codingprotein-coding
Descriptionannexin A2annexin IIannexin-2calpactin I heavy chaincalpactin I heavy polypeptidecalpactin-1 heavy chainchromobindin 8epididymis secretory protein Li 270epididymis secretory sperm binding proteinlipocortin IIplacental anticoagulant protein IVprserine/threonine-protein kinase SMG1PI-3-kinase-related kinase SMG-1SMG1 phosphatidylinositol 3-kinase-related kinaselambda-interacting proteinlambda/iota protein kinase C-interacting proteinsmg-1 homolog, phosphatidylinositol 3-kinase-related kinase
Modification date2020031320200313
UniProtAcc

P07355

.
Ensembl transtripts involved in fusion geneENST00000332680, ENST00000396024, 
ENST00000421017, ENST00000451270, 
ENST00000557937, 		ENST00000565224, 
ENST00000567737, ENST00000389467, 
ENST00000446231, 
Fusion gene scores* DoF score22 X 20 X 7=308017 X 19 X 7=2261
# samples 2318
** MAII scorelog2(23/3080*10)=-3.74322458463789
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/2261*10)=-3.65089218042185
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANXA2 [Title/Abstract] AND SMG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANXA2(60646353)-SMG1(18883946), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneANXA2

GO:0001921

positive regulation of receptor recycling

22848640

HgeneANXA2

GO:0031340

positive regulation of vesicle fusion

2138016

HgeneANXA2

GO:0032804

negative regulation of low-density lipoprotein particle receptor catabolic process

22848640

HgeneANXA2

GO:0036035

osteoclast development

7961821

HgeneANXA2

GO:1905581

positive regulation of low-density lipoprotein particle clearance

22848640

HgeneANXA2

GO:1905597

positive regulation of low-density lipoprotein particle receptor binding

22848640

HgeneANXA2

GO:1905602

positive regulation of receptor-mediated endocytosis involved in cholesterol transport

22848640

TgeneSMG1

GO:0000184

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

11544179

TgeneSMG1

GO:0018105

peptidyl-serine phosphorylation

11544179|15175154

TgeneSMG1

GO:0046777

protein autophosphorylation

11331269|11544179

TgeneSMG1

GO:0046854

phosphatidylinositol phosphorylation

11331269

TgeneSMG1

GO:2001020

regulation of response to DNA damage stimulus

15175154


check buttonFusion gene breakpoints across ANXA2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SMG1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-B6-A0IQ-01AANXA2chr15

60646353

-SMG1chr16

18883946

-


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Fusion Gene ORF analysis for ANXA2-SMG1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000332680ENST00000565224ANXA2chr15

60646353

-SMG1chr16

18883946

-
5CDS-intronENST00000332680ENST00000567737ANXA2chr15

60646353

-SMG1chr16

18883946

-
5CDS-intronENST00000396024ENST00000565224ANXA2chr15

60646353

-SMG1chr16

18883946

-
5CDS-intronENST00000396024ENST00000567737ANXA2chr15

60646353

-SMG1chr16

18883946

-
5CDS-intronENST00000421017ENST00000565224ANXA2chr15

60646353

-SMG1chr16

18883946

-
5CDS-intronENST00000421017ENST00000567737ANXA2chr15

60646353

-SMG1chr16

18883946

-
5CDS-intronENST00000451270ENST00000565224ANXA2chr15

60646353

-SMG1chr16

18883946

-
5CDS-intronENST00000451270ENST00000567737ANXA2chr15

60646353

-SMG1chr16

18883946

-
In-frameENST00000332680ENST00000389467ANXA2chr15

60646353

-SMG1chr16

18883946

-
In-frameENST00000332680ENST00000446231ANXA2chr15

60646353

-SMG1chr16

18883946

-
In-frameENST00000396024ENST00000389467ANXA2chr15

60646353

-SMG1chr16

18883946

-
In-frameENST00000396024ENST00000446231ANXA2chr15

60646353

-SMG1chr16

18883946

-
In-frameENST00000421017ENST00000389467ANXA2chr15

60646353

-SMG1chr16

18883946

-
In-frameENST00000421017ENST00000446231ANXA2chr15

60646353

-SMG1chr16

18883946

-
In-frameENST00000451270ENST00000389467ANXA2chr15

60646353

-SMG1chr16

18883946

-
In-frameENST00000451270ENST00000446231ANXA2chr15

60646353

-SMG1chr16

18883946

-
intron-3CDSENST00000557937ENST00000389467ANXA2chr15

60646353

-SMG1chr16

18883946

-
intron-3CDSENST00000557937ENST00000446231ANXA2chr15

60646353

-SMG1chr16

18883946

-
intron-intronENST00000557937ENST00000565224ANXA2chr15

60646353

-SMG1chr16

18883946

-
intron-intronENST00000557937ENST00000567737ANXA2chr15

60646353

-SMG1chr16

18883946

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000396024ANXA2chr1560646353-ENST00000389467SMG1chr1618883946-1456374813998463235
ENST00000396024ANXA2chr1560646353-ENST00000446231SMG1chr1618883946-1456074813998433234
ENST00000451270ANXA2chr1560646353-ENST00000389467SMG1chr1618883946-145157005597983247
ENST00000451270ANXA2chr1560646353-ENST00000446231SMG1chr1618883946-145127005597953246
ENST00000332680ANXA2chr1560646353-ENST00000389467SMG1chr1618883946-145297147298123246
ENST00000332680ANXA2chr1560646353-ENST00000446231SMG1chr1618883946-145267147298093245
ENST00000421017ANXA2chr1560646353-ENST00000389467SMG1chr1618883946-1453972413698223228
ENST00000421017ANXA2chr1560646353-ENST00000446231SMG1chr1618883946-1453672413698193227

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000396024ENST00000389467ANXA2chr1560646353-SMG1chr1618883946-0.0003545130.9996455
ENST00000396024ENST00000446231ANXA2chr1560646353-SMG1chr1618883946-0.0005542790.99944574
ENST00000451270ENST00000389467ANXA2chr1560646353-SMG1chr1618883946-0.0003402450.9996598
ENST00000451270ENST00000446231ANXA2chr1560646353-SMG1chr1618883946-0.0005290710.9994709
ENST00000332680ENST00000389467ANXA2chr1560646353-SMG1chr1618883946-0.0003262720.9996737
ENST00000332680ENST00000446231ANXA2chr1560646353-SMG1chr1618883946-0.000506360.9994936
ENST00000421017ENST00000389467ANXA2chr1560646353-SMG1chr1618883946-0.0003566080.9996433
ENST00000421017ENST00000446231ANXA2chr1560646353-SMG1chr1618883946-0.0005520890.9994479

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Fusion Genomic Features for ANXA2-SMG1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ANXA2-SMG1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:60646353/chr16:18883946)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ANXA2

P07355

.
FUNCTION: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9 (PubMed:18799458, PubMed:24808179, PubMed:22848640). {ECO:0000269|PubMed:18799458, ECO:0000269|PubMed:22848640, ECO:0000269|PubMed:24808179}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANXA2chr15:60646353chr16:18883946ENST00000332680-8132_24214358.0RegionS100A10-binding site
HgeneANXA2chr15:60646353chr16:18883946ENST00000396024-9142_24196340.0RegionS100A10-binding site
HgeneANXA2chr15:60646353chr16:18883946ENST00000421017-9142_24196340.0RegionS100A10-binding site
HgeneANXA2chr15:60646353chr16:18883946ENST00000451270-8132_24196340.0RegionS100A10-binding site
HgeneANXA2chr15:60646353chr16:18883946ENST00000332680-813105_176214358.0RepeatAnnexin 2
HgeneANXA2chr15:60646353chr16:18883946ENST00000332680-81333_104214358.0RepeatAnnexin 1
HgeneANXA2chr15:60646353chr16:18883946ENST00000396024-914105_176196340.0RepeatAnnexin 2
HgeneANXA2chr15:60646353chr16:18883946ENST00000396024-91433_104196340.0RepeatAnnexin 1
HgeneANXA2chr15:60646353chr16:18883946ENST00000421017-914105_176196340.0RepeatAnnexin 2
HgeneANXA2chr15:60646353chr16:18883946ENST00000421017-91433_104196340.0RepeatAnnexin 1
HgeneANXA2chr15:60646353chr16:18883946ENST00000451270-813105_176196340.0RepeatAnnexin 2
HgeneANXA2chr15:60646353chr16:18883946ENST00000451270-81333_104196340.0RepeatAnnexin 1
TgeneSMG1chr15:60646353chr16:18883946ENST0000044623112631283_18666303662.0DomainFAT
TgeneSMG1chr15:60646353chr16:18883946ENST0000044623112632150_24786303662.0DomainPI3K/PI4K
TgeneSMG1chr15:60646353chr16:18883946ENST0000044623112633629_36616303662.0DomainFATC
TgeneSMG1chr15:60646353chr16:18883946ENST0000044623112631817_18526303662.0RepeatNote=HEAT

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANXA2chr15:60646353chr16:18883946ENST00000332680-813189_261214358.0RepeatAnnexin 3
HgeneANXA2chr15:60646353chr16:18883946ENST00000332680-813265_336214358.0RepeatAnnexin 4
HgeneANXA2chr15:60646353chr16:18883946ENST00000396024-914189_261196340.0RepeatAnnexin 3
HgeneANXA2chr15:60646353chr16:18883946ENST00000396024-914265_336196340.0RepeatAnnexin 4
HgeneANXA2chr15:60646353chr16:18883946ENST00000421017-914189_261196340.0RepeatAnnexin 3
HgeneANXA2chr15:60646353chr16:18883946ENST00000421017-914265_336196340.0RepeatAnnexin 4
HgeneANXA2chr15:60646353chr16:18883946ENST00000451270-813189_261196340.0RepeatAnnexin 3
HgeneANXA2chr15:60646353chr16:18883946ENST00000451270-813265_336196340.0RepeatAnnexin 4


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Fusion Gene Sequence for ANXA2-SMG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>5042_5042_1_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000332680_SMG1_chr16_18883946_ENST00000389467_length(transcript)=14529nt_BP=714nt
CTCAGCATTTGGGGACGCTCTCAGCTCTCGGCGCACGGCCCAGGTAAGCGGGGCGCGCCCTGCCCGCCCGCGATGGGCCGCCAGCTAGCG
GGGTGTGGAGACGCTGGGAAGAAGGCTTCCTTCAAAATGTCTACTGTTCACGAAATCCTGTGCAAGCTCAGCTTGGAGGGTGATCACTCT
ACACCCCCAAGTGCATATGGGTCTGTCAAAGCCTATACTAACTTTGATGCTGAGCGGGATGCTTTGAACATTGAAACAGCCATCAAGACC
AAAGGTGTGGATGAGGTCACCATTGTCAACATTTTGACCAACCGCAGCAATGCACAGAGACAGGATATTGCCTTCGCCTACCAGAGAAGG
ACCAAAAAGGAACTTGCATCAGCACTGAAGTCAGCCTTATCTGGCCACCTGGAGACGGTGATTTTGGGCCTATTGAAGACACCTGCTCAG
TATGACGCTTCTGAGCTAAAAGCTTCCATGAAGGGGCTGGGAACCGACGAGGACTCTCTCATTGAGATCATCTGCTCCAGAACCAACCAG
GAGCTGCAGGAAATTAACAGAGTCTACAAGGAAATGTACAAGACTGATCTGGAGAAGGACATTATTTCGGACACATCTGGTGACTTCCGC
AAGCTGATGGTTGCCCTGGCAAAGGGTAGAAGAGCAGAGGATGGCTCTGTCATTGATTATGAACTGATTGACCAAGATGCTCGGATGTGG
GCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTAT
GCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGAT
GGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAAC
CTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTC
TCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGT
CTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGT
ATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCT
TTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGG
AACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCA
CGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCA
CTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGT
CAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAA
TTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACT
TGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTT
GACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAA
CTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAA
CAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTT
GACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTG
TCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCT
GTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAA
TCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGA
GGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAA
TTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAG
TACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTG
CAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTA
CGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGAA
CAAACAGTCCCAATTAGAAGCCATCTCATGGAATTAGGTCTAACAGCAGCAAAATTTGCTAGAAAACGAGGGAATGTGTCCCTTGCAACA
AGACTGCTGGCACAGTGCAGTGAAGTTCAGCTGGGAAAGACCACCACTGCACAGGATTTAGTCCAACATTTTAAAAAACTATCAACCCAA
GGTCAAGTGGATGAAAAATGGGGGCCCGAACTTGATATTGAAAAAACCAAATTGCTTTATACAGCAGGCCAGTCAACACATGCAATGGAA
ATGTTGAGTTCTTGTGCCATATCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGTTGCTAAATCAATTCTGACACTGGCTAAATGGATC
CAGGCAGAATGGAAAGAGATTTCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCACCAACAGAACTTCACAGGTCTTTCTACTTTGTCT
AAAAACATACTCACTCTAATAGAACTGCCATCTGTTAATACGATGGAAGAAGAGTATCCTCGGATCGAGAGTGAATCTACAGTGCATATT
GGAGTTGGAGAACCTGACTTCATTTTGGGACAGTTGTATCACCTGTCTTCAGTACAGGCACCTGAAGTAGCCAAATCTTGGGCAGCGTTG
GCCAGCTGGGCTTATAGGTGGGGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGAAGGTGTTCGTCTGCTGCCTAGAGAAAAATCTGAA
GTTCAGAATCTACTTCCAGACACTATAACTGAGGAAGAGAAAGAGAGAATATATGGTATTCTTGGACAGGCTGTGTGTCGGCCGGCGGGG
ATTCAGGATGAAGATATAACACTTCAGATAACTGAGAGTGAAGACAACGAAGAAGATGACATGGTTGATGTTATCTGGCGTCAGTTGATA
TCAAGCTGCCCATGGCTTTCAGAACTTGATGAAAGTGCAACTGAAGGAGTTATTAAAGTGTGGAGGAAAGTTGTAGATAGAATATTCAGC
CTGTACAAACTCTCTTGCAGTGCATACTTTACTTTCCTTAAACTCAACGCTGGTCAAATTCCTTTAGATGAGGATGACCCTAGGCTGCAT
TTAAGTCACAGAGTGGAACAGAGCACTGATGACATGATTGTGATGGCCACATTGCGCCTGCTGCGGTTGCTCGTGAAGCATGCTGGTGAG
CTTCGGCAGTATCTGGAGCACGGCTTGGAGACAACACCCACTGCACCATGGAGAGGAATTATTCCGCAACTTTTCTCACGCTTAAACCAC
CCTGAAGTGTATGTGCGCCAAAGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGATTCCCCACATCTCATATTGTATCCTGCAATAGTG
GGTACCATATCGCTTAGTAGTGAATCCCAGGCTTCAGGAAATAAATTTTCCACTGCAATTCCAACTTTACTTGGCAATATTCAAGGAGAA
GAATTGCTGGTTTCTGAATGTGAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAATAAGGATGAACCTAAAAGTGGATTAAATGAAGAC
CAAGCCATGATGCAGGATTGTTACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAACCCCACCATGGTATTACAGGTTCAGATGCTCGTG
GCTGAACTGCGCAGGGTCACTGTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCTGCAACAACACATGTATGTCCTGAGACGAATTCAG
CAGCTTGAAGATGAGGTGAAGAGAGTCCAGAACAACAACACCTTACGCAAAGAAGAGAAAATTGCAATCATGAGGGAGAAGCACACAGCT
TTGATGAAGCCCATCGTATTTGCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCCTGCAGAAACACCTCATGAAAAATGGTTTCAGGAT
AACTATGGTGATGCCATTGAAAATGCCCTAGAAAAACTGAAGACTCCATTGAACCCTGCAAAGCCTGGGAGCAGCTGGATTCCATTTAAA
GAGATAATGCTAAGTTTGCAACAGAGAGCACAGAAACGTGCAAGTTACATCTTGCGTCTTGAAGAAATCAGTCCATGGTTGGCTGCCATG
ACTAACACTGAAATTGCTCTTCCTGGGGAAGTCTCAGCCAGAGACACTGTCACAATCCATAGTGTGGGCGGAACCATCACAATCTTACCG
ACTAAAACCAAGCCAAAGAAACTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCCTTATCTTTTCAAAGGACTGGAGGATTTACATCTG
GATGAGAGAATAATGCAGTTCCTATCTATTGTGAATACCATGTTTGCTACAATTAATCGCCAAGAAACACCCCGGTTCCATGCTCGACAC
TATTCTGTAACACCACTAGGAACAAGATCAGGACTAATCCAGTGGGTAGATGGAGCCACACCCTTATTTGGTCTTTACAAACGATGGCAA
CAACGGGAAGCTGCCTTACAAGCACAAAAGGCCCAAGATTCCTACCAAACTCCTCAGAATCCTGGAATTGTACCCCGTCCTAGTGAACTT
TATTACAGTAAAATTGGCCCTGCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTCCCGTCGGGATTGGCCTCTTCATGTAATGAAGGCA
GTATTGGAAGAGTTAATGGAGGCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTGGTCATCTTGCACAACACCTGATGAATGGTGGAGA
GTTACGCAGTCTTATGCAAGATCTACTGCAGTCATGTCTATGGTTGGATACATAATTGGCCTTGGAGACAGACATCTGGATAATGTTCTT
ATAGATATGACGACTGGAGAAGTTGTTCACATAGATTACAATGTTTGCTTTGAAAAAGGTAAAAGCCTTAGAGTTCCTGAGAAAGTACCT
TTTCGAATGACACAAAACATTGAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGTATTTAGGCTTTCATGTGAGCAGGTTTTACACATT
ATGCGGCGTGGCAGAGAGACCCTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCCTCTGGTGGACTGGACAGCAGGAGGCGAGGCTGGG
TTTGCTGGTGCTGTCTATGGTGGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAAGAGAGAGATGGAGCGAGAGATCACCCGCAGCCTG
TTTTCTTCTAGAGTAGCTGAGATTAAGGTGAACTGGTTTAAGAATAGAGATGAGATGCTGGTTGTGCTTCCCAAGTTGGACGGTAGCTTA
GATGAATACCTAAGCTTGCAAGAGCAACTGACAGATGTGGAAAAACTGCAGGGCAAACTACTGGAGGAAATAGAGTTTCTAGAAGGAGCT
GAAGGGGTGGATCATCCTTCTCATACTCTGCAACACAGGTATTCTGAGCACACCCAACTACAGACTCAGCAAAGAGCTGTTCAGGAAGCA
ATCCAGGTGAAGCTGAATGAATTTGAACAATGGATAACACATTATCAGGCTGCATTCAATAATTTAGAAGCAACACAGCTTGCAAGCTTG
CTTCAAGAGATAAGCACACAAATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAACAGCCTTTCTGCAGAATGCTGGTCAGGCCCACTTG
ATTAGCCAGTGCGAGCAGCTGGAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCGCTCCGTGCTCCGTGGCTGTCTGGAGCAACTGCAT
CACTATGCAACCGTGGCCCTGCAGTATCCGAAGGCCATATTTCAGAAACATCGAATTGAACAGTGGAAGACCTGGATGGAAGAGCTCATC
TGTAACACCACAGTAGAGCGTTGTCAAGAGCTCTATAGGAAATATGAAATGCAATATGCTCCCCAGCCACCCCCAACAGTGTGTCAGTTC
ATCACTGCCACTGAAATGACCCTGCAGCGATACGCAGCAGACATCAACAGCAGACTTATTAGACAAGTGGAACGCTTGAAACAGGAAGCT
GTCACTGTGCCAGTTTGTGAAGATCAGTTGAAAGAAATTGAACGTTGCATTAAAGTTTTCCTTCATGAGAATGGAGAAGAAGGATCTTTG
AGTCTAGCAAGTGTTATTATTTCTGCCCTTTGTACCCTTACAAGGCGTAACCTGATGATGGAAGGTGCAGCGTCAAGTGCTGGAGAACAG
CTGGTTGATCTGACTTCTCGGGATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTATGAGCGGAAACGTCACCTGCTTGGTTCAGTTACTG
AAGCAGTGCCACCTGGTGCCACAGGACTTAGATATCCCGAACCCCATGGAAGCGTCTGAGACAGTTCACTTAGCCAATGGAGTGTATACC
TCACTTCAGGAATTGAATTCGAATTTCCGGCAAATCATATTTCCAGAAGCACTTCGATGTTTAATGAAAGGGGAATACACGTTAGAAAGT
ATGCTGCATGAACTGGACGGTCTTATTGAGCAGACCACCGATGGCGTTCCCCTGCAGACTCTAGTGGAATCTCTTCAGGCCTACTTAAGA
AACGCAGCTATGGGACTGGAAGAAGAAACACATGCTCATTACATCGATGTTGCCAGACTACTACATGCTCAGTACGGTGAATTAATCCAA
CCGAGAAATGGTTCAGTTGATGAAACACCCAAAATGTCAGCTGGCCAGATGCTTTTGGTAGCATTCGATGGCATGTTTGCTCAAGTTGAA
ACTGCTTTCAGCTTATTAGTTGAAAAGTTGAACAAGATGGAAATTCCCATAGCTTGGCGAAAGATTGACATCATAAGGGAAGCCAGGAGT
ACTCAAGTTAATTTTTTTGATGATGATAATCACCGGCAGGTGCTAGAAGAGATTTTCTTTCTAAAAAGACTACAGACTATTAAGGAGTTC
TTCAGGCTCTGTGGTACCTTTTCTAAAACATTGTCAGGATCAAGTTCACTTGAAGATCAGAATACTGTGAATGGGCCTGTACAGATTGTC
AATGTGAAAACCCTTTTTAGAAACTCTTGTTTCAGTGAAGACCAAATGGCCAAACCTATCAAGGCATTCACAGCTGACTTTGTGAGGCAG
CTCTTGATAGGGCTACCCAACCAAGCCCTCGGACTCACACTGTGCAGTTTTATCAGTGCTCTGGGTGTAGACATCATTGCTCAAGTAGAG
GCAAAGGACTTTGGTGCCGAAAGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGCGGTGGAACATAACATCCAGATAGGGAAGTTCTCT
CAGCTGGTTATGAACAGGGCAACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAAGAAGCATGACTTGGTGCGAAGGCTAGAAACCAGT
ATTTCTTCTTGTAAGACAAGCCTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCAGCAGTGGCAACATGAAGATCTACTTATCAATAGA
CCACAAGCCATGTCAGTCACACCTCCCCCACGGTCTGCTATCCTAACCAGCATGAAAAAGAAGCTGCATACCCTGAGCCAGATTGAAACT
TCTATTGCAACAGTTCAGGAGAAGCTAGCTGCACTTGAATCAAGTATTGAACAGCGACTCAAGTGGGCAGGTGGTGCCAACCCTGCATTG
GCCCCTGTACTACAAGATTTTGAAGCAACGATAGCTGAAAGAAGAAATCTTGTCCTTAAAGAGAGCCAAAGAGCAAGTCAGGTCACATTT
CTCTGCAGCAATATCATTCATTTTGAAAGTTTACGAACAAGAACTGCAGAAGCCTTAAACCTGGATGCGGCGTTATTTGAACTAATCAAG
CGATGTCAGCAGATGTGTTCGTTTGCATCACAGTTTAACAGTTCAGTGTCTGAGTTAGAGCTTCGTTTATTACAGAGAGTGGACACTGGT
CTTGAACATCCTATTGGCAGCTCTGAATGGCTTTTGTCAGCACACAAACAGTTGACCCAGGATATGTCTACTCAGAGGGCAATTCAGACA
GAGAAAGAGCAGCAGATAGAAACGGTCTGTGAAACAATTCAGAATCTGGTTGATAATATAAAGACTGTGCTCACTGGTCATAACCGACAG
CTTGGAGATGTCAAACATCTCTTGAAAGCTATGGCTAAGGATGAAGAAGCTGCTCTGGCAGATGGTGAAGATGTTCCCTATGAGAACAGT
GTTAGGCAGTTTTTGGGTGAATATAAATCATGGCAAGACAACATTCAAACAGTTCTATTTACATTAGTCCAGGCTATGGGTCAGGTTCGA
AGTCAAGAACACGTTGAAATGCTCCAGGAAATCACTCCCACCTTGAAAGAACTGAAAACACAAAGTCAGAGTATCTATAATAATTTAGTG
AGTTTTGCATCACCCTTAGTCACCGATGCAACAAATGAATGTTCGAGTCCAACGTCATCTGCTACTTATCAGCCATCCTTCGCTGCAGCA
GTCCGGAGTAACACTGGCCAGAAGACTCAGCCTGATGTCATGTCACAGAATGCTAGAAAGCTGATCCAAAAAAATCTTGCTACATCAGCT
GATACTCCACCAAGCACCGTTCCAGGAACTGGCAAGAGTGTTGCTTGTAGTCCTAAAAAGGCAGTCAGAGACCCTAAAACTGGGAAAGCG
GTGCAAGAGAGAAACTCCTATGCAGTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTTAGAGGGCCGAGATGTTGATCCGAATAGGAGGATG
TCAGTTGCTGAACAGGTTGACTATGTCATTAAGGAAGCAACTAATCTAGATAACTTGGCTCAGCTGTATGAAGGTTGGACAGCCTGGGTG
TGAATGGCAAGACAGTAGATGAGTCTGGTTAAGCGAGGTCAGACATCCACCAGAATCAACTCAGCCTCAGGCATCCAAAGCCACACCACA
GTCGGTGGTGATGCAACTGGGGGCTTACTCTGAGGAAACCTAGGAAATCTCGGTGCACTAGGAAGTGAATCCCGCAGGACAGCTGCACTC
AGGGATACGCCCAACACCATGGCCTGCAACCCCAGGGTCAAGGGTGAAGGAAAGCAAGCTCACCGCCTGAACACGGAGATTGTCTTTCTG
CCACAGAACAGCAGCAGACGTGTCGGGAGGTTAGCTGCGGAAAGAAATCGGGATGCCGCGGAGCACAGAGTGATTTGGAACTCCATTCCA
CCTGACCCTGTGTGTACAATCCAGGAAAAAAACAAACCCCACTCAGAAACAGAGAAAACTGGGGTCGCGAAGAAATCACAGCCAAGGAAG
ATTTGATGCATTCAGATTCTCGTGTAACACTTGTTGCTTGGCAACAGTACTGGTTGGGTTGACCAGTAAGTAGAAAAAGGCTAAAGGCTA
TGCGATATGAATTTCAGAAATGGACTGAAAATGGAGAGCTATGTAACAGATACACTACAGTAGAAGAACTTACTTCTGAAATGAAGGGAA
AAAAACCACCCCATCGTTCCCTACTCCTCCCCACCACTTACCCGTTCCCCCTTTACCTAATCTAGTAGATTAGCCATCTTTCAAATTCAC
TTTTATTTCAGTCCTTATATTTCATATACTTCCGTCTCGATGCTGTTAACAACTTCTGATAACATGGAAAATTCAAGGATTGTTTAAAGG
TCTGATGATCACACACAAAATGTAATTCCGGTTATTTAAGTCATTTCTGTGATTCTATCATGTACAGTTTCCAGAATTGTCACTGTGCAT
TCAAAAGTAATGAATCTAACAGACATTTGATTTAATGTACACTCCCTTTTGCTTATAGTGTGCATTTTTTTTGGAGGTCATTCAAATTTT
CCCTCTTCTGTGATAGCTGTAGTTTCTTTCATAGAAAGTAGCTAATCCAGTGTAATCTTTTACCTTTTTAAAAACCAAGATAGAGTATCT
ATTAGAGTTTTACATTGTTGATGATAGATTAACAATAAAGTGATGTTCTGGTGGAGGTAGACTGAAATTTTTTTAATTCATGTTTTTCAT
TTGATACTTTTAATTTACACTTAGTAAATTAAAAGTTGTTTAATTTACTTGGCATTTTAGGACATGTACATGAAACAGTGAAAATGAGAT
CCACCAACATCTTTTATTAAGTTCAGTTATTAGTCTGTGAAGTGCTTTACTTTTTGCACAATTTTAATAGCTTGCTATTCAGTAATACAT
TATAGTGAATTCATGATCAAGGTTTCCTTAAATTTAGCATTGCATTTCAGTACTGACTGTGTAAGCTAAATTGCTGATCCAAAATAAAAA
CCCAGACTAGAATAGGGTTCTTAAAATCAAGTATCAATACAAAATAGAACACAATTAAAATCTTAATTGTTGGCTGGGCACAGTGGCTCA
CGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCATGAGGTTAGGAGAGCGAGACCATCCTGGCTAACACGGTGAAACCCC
GTCTTTACTAAAAATACAAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGG
CGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGCTAGACTCTGTGTCAAAAAT
AAATGACTAGATAAAAAAAAAAATTGTTTGAGTACATTTTCCCTGCATTTTAGAGATTAGGACAGTGGTCACTTTCTAGTTGCCGTCTTC
ACAGACAAACTTGAAAGGTATTAAGGAAAAAATTCCACATAGCTCTGGGCCTTTTTTGTATTCTGATTGCCACGTTAATCTGTAATCGTT
AAGTACCCATGAAAGAATGTGTTTCAGTATCAGTGCTTTTTTGGTACTTTAACAAGTATTGTAGGCACGGTGGATTTTTTTGAAATACCC
ATGTGTCCAATAGCAAGTTAAGGAACCTAGCGCATCAAATTTTGTTTTCTTCATTCATTTGGAACCTTATTTTCGCAAAAAACCTAGCTG
GAATAATAATGCCATATTGTATTTTGCACACTGCTTTATTTTCTAGAGGCTCTGGGAGCAAATTACATTCATCACATTACCTCTGCTCTC
TCAAGATTAAAGTCTTTCAGCAACATTCTTTATTGTCATCATAAGGAAAAACTTTTATCGCAATGATAGTCAGTTCACATTAGTTTAGCA
CTATAGATAGTATTCAGAAATTGCTTTCTCTTTGGTAAAGAAGATAAATAGGTGAATTTTATTGCCTGTGTTTTCAGGCTTCAGAGGTAC
CTGGCACCTTACTCAAGCAAAAACAAAAAACAGCTTTACTTCAAAAGCATGTGCCTCTGGTAAATTATCCATCACTTTTGTTTTAAAGTG
GTCCCTCCAAGAATAATGTGGCATACACAGTGGGTTTGGTTGTAAGGCAGATGTAATAGATGACTTCAAAAGCCTGCTCCTTACTGCACT
CTGGACAAGGCCCTGGTCTGTATAGTTTGGCTTCCTCTGTTAAGTCATTCTACAAGGTGACTTGCCATTTGAACTTTCGTAAGAGACCTC
AGCAGTTAGACTGAGAAAAGTTAGAGTGCTGTAGTTATGAAGTCATACATTTTTGATAAAATACCTGTGGAAAACCAGGGATCCTCTCCT
GTTTCTCTCTCTTGCCTCCCCCTTTCCCTCCATTCCTCTGTCGCCTCCCCCTCTCCTCCACTTTCTTTAAGAATCAGGGGGTACAGAATA
ACCTACAAACAACCTCTTCAAAGTACCCTTGGAAATTGAAGTTCAATCTTAAGTTTTTTGCTGTCTTTAATTTACTAGAATTGCCTAATT
TTTAGTTGATTTCTCTACAGAGCTTAGCTTGTGTAGTTATTTCTCTTTTACTGTTGCTTTGGTGTGTCTTGAAGTTTGATTGATTATTTT
TGGTCATTGAGTTCTTAGTGTAGTTTGCTAGATGATTATTAAGATTCTTTTGTGTCTGACACTTGTGGTGAGTTGCTTTTGAAATCTGTT
GAGATTTCCATGTGAGAACTGATAATCAGGCTCTTGATCTGCTTCCCTAAATTACTTTTTTAGAGCCCAAACCCCAGGTTTAGGGTGAGG
GTTTGTAATACAAAGAAACACTTCCATCACTTCTGCCCTTAACCCTTGCCTCTATTACCTAAGCTTAGTAAGTAGTTTTCTTAATATTGT
CCAATGTTTGGTGTTATCTGCATTGTTTTTTGTTTTTTTAATTGTGGTTGTTCTGACGTGTGAAATTTAAGGAAAGAGCCATTTTTTAAA
AATGCCGAGCAGGGCAATGCAAGTACAGCCAAATATTAGACTTGATGTGCAATCTTCGGTCCTTTTTAATCTGGGGTATTATAGGCAGTA
CTTTAAATTGCAAAGTCTTCCGGGCCTATTTTCCTCTACATTTTTGTAATTAACTCTGGGGGCTTACTTGTTTTGGCAGTACTGAAATCA
AAGGAGCTGGTTCTTCTTTTCTCCCAATTATTTTCATATGAAAGCACCTACAATTAGCCTGTTAGTCCTATTCAGATACATCAAATATCA
GTGAATGCTTTACTATTCGCACATTTAAGCATCTTTGTTTTACATAAAATTAGAGTATGAAAACCAGTGTTCAATTTTTTATCTTGTTGA
GCTTGTAAAATGCCAGCAATTTAAAACTAGGACTTTTCCCCCCATAAGCCAAGGAGGTAGAATTACTAATACAAGGGTTAAAGAAGGTAG
ATTTTGTTTTCAATATTTGGGTAATATTAGAAAGATTCTTCCCACAGGGAAGAACTAGCAAGTGTCCCAATTTTTTCCAAACGTTGGGGA
GGGGAAAATTCACTGTATCATGAAACCCTAAGGGTTTGTTGCACTTCCTGCTTTTTAGGCCTGGATAACAGTATCACCATCCTTATTTAC
AGAAGGGTAAAACTGACTCTTAATGAGAAAAGCTTTATAAGTTCAAGGGCTGTAAAATATGAACTACTTAGGGTCGTTTGCCTTCCATGG
GAACTTGGCTAGACTTAGAAAAAGCTGTTTGTTGTGCTAATGTAAAAGTGTCATACAATTTAGAAGATTTTTGAAGATGGTAAACTTAGA
AGAATTCTATGTTCTGAAATGCACACTTTTAGAATGTTTTTCTTTGAAAACAGGCTAATAGTTTTTTCTTTTTTTGACAAAGTTTCAGCT
CCTCTTTAAAGTTATTGTGTCATTTTTCTGGTTTAAATTTCCCTTATATTTCCACCTGTAATGTCAGTGGCAACAACATCATACTTCACT
TACTTGTTAATTTACTTTTTACCCTTATTCTAAGAGCAAGTTGAGTTGAACTGAATCTTCCTTGTCTTAGTAACAATGTATAAATAGTGG
CTTTTCTGTACAAAAGGTTGTAATGCCTCCTGATGGATATAATTTTGTGATTGTATTTAAAAGTTGAATAAATCACACCAGCTTCCTGAA
AATGTTCATAATGCATCTTTTGGAAAACAAATACATGCCTACTTTGTGCATATTTGCATTAACATGGCAAAGATTGTATGAAATACCTGT

>5042_5042_1_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000332680_SMG1_chr16_18883946_ENST00000389467_length(amino acids)=3246AA_BP=214
MGRQLAGCGDAGKKASFKMSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIA
FAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISD
TSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSS
SPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNIC
LQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVI
SFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLN
PDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAV
TVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVD
CCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKA
DFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSI
TENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQL
LEKIKEQTVPIRSHLMELGLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQ
STHAMEMLSSCAISFCKSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIES
ESTVHIGVGEPDFILGQLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQA
VCRPAGIQDEDITLQITESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDE
DDPRLHLSHRVEQSTDDMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLI
LYPAIVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVL
QVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPH
EKWFQDNYGDAIENALEKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGG
TITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFG
LYKRWQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTT
PDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSC
EQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLP
KLDGSLDEYLSLQEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEA
TQLASLLQEISTQMDLGPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWKT
WMEELICNTTVERCQELYRKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHEN
GEEGSLSLASVIISALCTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVHL
ANGVYTSLQELNSNFRQIIFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQ
YGELIQPRNGSVDETPKMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKRL
QTIKEFFRLCGTFSKTLSGSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVD
IIAQVEAKDFGAESKVSVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQQWQHE
DLLINRPQAMSVTPPPRSAILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQR
ASQVTFLCSNIIHFESLRTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMST
QRAIQTEKEQQIETVCETIQNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQ
AMGQVRSQEHVEMLQEITPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQK
NLATSADTPPSTVPGTGKSVACSPKKAVRDPKTGKAVQERNSYAVSVWKRVKAKLEGRDVDPNRRMSVAEQVDYVIKEATNLDNLAQLYE

--------------------------------------------------------------
>5042_5042_2_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000332680_SMG1_chr16_18883946_ENST00000446231_length(transcript)=14526nt_BP=714nt
CTCAGCATTTGGGGACGCTCTCAGCTCTCGGCGCACGGCCCAGGTAAGCGGGGCGCGCCCTGCCCGCCCGCGATGGGCCGCCAGCTAGCG
GGGTGTGGAGACGCTGGGAAGAAGGCTTCCTTCAAAATGTCTACTGTTCACGAAATCCTGTGCAAGCTCAGCTTGGAGGGTGATCACTCT
ACACCCCCAAGTGCATATGGGTCTGTCAAAGCCTATACTAACTTTGATGCTGAGCGGGATGCTTTGAACATTGAAACAGCCATCAAGACC
AAAGGTGTGGATGAGGTCACCATTGTCAACATTTTGACCAACCGCAGCAATGCACAGAGACAGGATATTGCCTTCGCCTACCAGAGAAGG
ACCAAAAAGGAACTTGCATCAGCACTGAAGTCAGCCTTATCTGGCCACCTGGAGACGGTGATTTTGGGCCTATTGAAGACACCTGCTCAG
TATGACGCTTCTGAGCTAAAAGCTTCCATGAAGGGGCTGGGAACCGACGAGGACTCTCTCATTGAGATCATCTGCTCCAGAACCAACCAG
GAGCTGCAGGAAATTAACAGAGTCTACAAGGAAATGTACAAGACTGATCTGGAGAAGGACATTATTTCGGACACATCTGGTGACTTCCGC
AAGCTGATGGTTGCCCTGGCAAAGGGTAGAAGAGCAGAGGATGGCTCTGTCATTGATTATGAACTGATTGACCAAGATGCTCGGATGTGG
GCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTAT
GCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGAT
GGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAAC
CTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTC
TCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGT
CTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGT
ATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCT
TTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGG
AACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCA
CGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCA
CTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGT
CAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAA
TTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACT
TGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTT
GACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAA
CTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAA
CAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTT
GACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTG
TCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCT
GTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAA
TCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGA
GGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAA
TTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAG
TACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTG
CAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTA
CGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGAA
CAAACAGTCCCAATTAGAAGCCATCTCATGGAATTAGGTCTAACAGCAGCAAAATTTGCTAGAAAACGAGGGAATGTGTCCCTTGCAACA
AGACTGCTGGCACAGTGCAGTGAAGTTCAGCTGGGAAAGACCACCACTGCACAGGATTTAGTCCAACATTTTAAAAAACTATCAACCCAA
GGTCAAGTGGATGAAAAATGGGGGCCCGAACTTGATATTGAAAAAACCAAATTGCTTTATACAGCAGGCCAGTCAACACATGCAATGGAA
ATGTTGAGTTCTTGTGCCATATCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGTTGCTAAATCAATTCTGACACTGGCTAAATGGATC
CAGGCAGAATGGAAAGAGATTTCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCACCAACAGAACTTCACAGGTCTTTCTACTTTGTCT
AAAAACATACTCACTCTAATAGAACTGCCATCTGTTAATACGATGGAAGAAGAGTATCCTCGGATCGAGAGTGAATCTACAGTGCATATT
GGAGTTGGAGAACCTGACTTCATTTTGGGACAGTTGTATCACCTGTCTTCAGTACAGGCACCTGAAGTAGCCAAATCTTGGGCAGCGTTG
GCCAGCTGGGCTTATAGGTGGGGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGAAGGTGTTCGTCTGCTGCCTAGAGAAAAATCTGAA
GTTCAGAATCTACTTCCAGACACTATAACTGAGGAAGAGAAAGAGAGAATATATGGTATTCTTGGACAGGCTGTGTGTCGGCCGGCGGGG
ATTCAGGATGAAGATATAACACTTCAGATAACTGAGAGTGAAGACAACGAAGAAGATGACATGGTTGATGTTATCTGGCGTCAGTTGATA
TCAAGCTGCCCATGGCTTTCAGAACTTGATGAAAGTGCAACTGAAGGAGTTATTAAAGTGTGGAGGAAAGTTGTAGATAGAATATTCAGC
CTGTACAAACTCTCTTGCAGTGCATACTTTACTTTCCTTAAACTCAACGCTGGTCAAATTCCTTTAGATGAGGATGACCCTAGGCTGCAT
TTAAGTCACAGAGTGGAACAGAGCACTGATGACATGATTGTGATGGCCACATTGCGCCTGCTGCGGTTGCTCGTGAAGCATGCTGGTGAG
CTTCGGCAGTATCTGGAGCACGGCTTGGAGACAACACCCACTGCACCATGGAGAGGAATTATTCCGCAACTTTTCTCACGCTTAAACCAC
CCTGAAGTGTATGTGCGCCAAAGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGATTCCCCACATCTCATATTGTATCCTGCAATAGTG
GGTACCATATCGCTTAGTAGTGAATCCCAGGCTTCAGGAAATAAATTTTCCACTGCAATTCCAACTTTACTTGGCAATATTCAAGGAGAA
GAATTGCTGGTTTCTGAATGTGAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAATAAGGATGAACCTAAAAGTGGATTAAATGAAGAC
CAAGCCATGATGCAGGATTGTTACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAACCCCACCATGGTATTACAGGTTCAGATGCTCGTG
GCTGAACTGCGCAGGGTCACTGTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCTGCAACAACACATGTATGTCCTGAGACGAATTCAG
CAGCTTGAAGATGAGGTGAAGAGAGTCCAGAACAACAACACCTTACGCAAAGAAGAGAAAATTGCAATCATGAGGGAGAAGCACACAGCT
TTGATGAAGCCCATCGTATTTGCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCCTGCAGAAACACCTCATGAAAAATGGTTTCAGGAT
AACTATGGTGATGCCATTGAAAATGCCCTAGAAAAACTGAAGACTCCATTGAACCCTGCAAAGCCTGGGAGCAGCTGGATTCCATTTAAA
GAGATAATGCTAAGTTTGCAACAGAGAGCACAGAAACGTGCAAGTTACATCTTGCGTCTTGAAGAAATCAGTCCATGGTTGGCTGCCATG
ACTAACACTGAAATTGCTCTTCCTGGGGAAGTCTCAGCCAGAGACACTGTCACAATCCATAGTGTGGGCGGAACCATCACAATCTTACCG
ACTAAAACCAAGCCAAAGAAACTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCCTTATCTTTTCAAAGGACTGGAGGATTTACATCTG
GATGAGAGAATAATGCAGTTCCTATCTATTGTGAATACCATGTTTGCTACAATTAATCGCCAAGAAACACCCCGGTTCCATGCTCGACAC
TATTCTGTAACACCACTAGGAACAAGATCAGGACTAATCCAGTGGGTAGATGGAGCCACACCCTTATTTGGTCTTTACAAACGATGGCAA
CAACGGGAAGCTGCCTTACAAGCACAAAAGGCCCAAGATTCCTACCAAACTCCTCAGAATCCTGGAATTGTACCCCGTCCTAGTGAACTT
TATTACAGTAAAATTGGCCCTGCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTCCCGTCGGGATTGGCCTCTTCATGTAATGAAGGCA
GTATTGGAAGAGTTAATGGAGGCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTGGTCATCTTGCACAACACCTGATGAATGGTGGAGA
GTTACGCAGTCTTATGCAAGATCTACTGCAGTCATGTCTATGGTTGGATACATAATTGGCCTTGGAGACAGACATCTGGATAATGTTCTT
ATAGATATGACGACTGGAGAAGTTGTTCACATAGATTACAATGTTTGCTTTGAAAAAGGTAAAAGCCTTAGAGTTCCTGAGAAAGTACCT
TTTCGAATGACACAAAACATTGAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGTATTTAGGCTTTCATGTGAGCAGGTTTTACACATT
ATGCGGCGTGGCAGAGAGACCCTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCCTCTGGTGGACTGGACAGCAGGAGGCGAGGCTGGG
TTTGCTGGTGCTGTCTATGGTGGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAAGAGAGAGATGGAGCGAGAGATCACCCGCAGCCTG
TTTTCTTCTAGAGTAGCTGAGATTAAGGTGAACTGGTTTAAGAATAGAGATGAGATGCTGGTTGTGCTTCCCAAGTTGGACGGTAGCTTA
GATGAATACCTAAGCTTGCAAGAGCAACTGACAGATGTGGAAAAACTGCAGGGCAAACTACTGGAGGAAATAGAGTTTCTAGAAGGAGCT
GAAGGGGTGGATCATCCTTCTCATACTCTGCAACACAGGTATTCTGAGCACACCCAACTACAGACTCAGCAAAGAGCTGTTCAGGAAGCA
ATCCAGGTGAAGCTGAATGAATTTGAACAATGGATAACACATTATCAGGCTGCATTCAATAATTTAGAAGCAACACAGCTTGCAAGCTTG
CTTCAAGAGATAAGCACACAAATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAACAGCCTTTCTGCAGAATGCTGGTCAGGCCCACTTG
ATTAGCCAGTGCGAGCAGCTGGAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCGCTCCGTGCTCCGTGGCTGTCTGGAGCAACTGCAT
CACTATGCAACCGTGGCCCTGCAGTATCCGAAGGCCATATTTCAGAAACATCGAATTGAACAGTGGAAGACCTGGATGGAAGAGCTCATC
TGTAACACCACAGTAGAGCGTTGTCAAGAGCTCTATAGGAAATATGAAATGCAATATGCTCCCCAGCCACCCCCAACAGTGTGTCAGTTC
ATCACTGCCACTGAAATGACCCTGCAGCGATACGCAGCAGACATCAACAGCAGACTTATTAGACAAGTGGAACGCTTGAAACAGGAAGCT
GTCACTGTGCCAGTTTGTGAAGATCAGTTGAAAGAAATTGAACGTTGCATTAAAGTTTTCCTTCATGAGAATGGAGAAGAAGGATCTTTG
AGTCTAGCAAGTGTTATTATTTCTGCCCTTTGTACCCTTACAAGGCGTAACCTGATGATGGAAGGTGCAGCGTCAAGTGCTGGAGAACAG
CTGGTTGATCTGACTTCTCGGGATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTATGAGCGGAAACGTCACCTGCTTGGTTCAGTTACTG
AAGCAGTGCCACCTGGTGCCACAGGACTTAGATATCCCGAACCCCATGGAAGCGTCTGAGACAGTTCACTTAGCCAATGGAGTGTATACC
TCACTTCAGGAATTGAATTCGAATTTCCGGCAAATCATATTTCCAGAAGCACTTCGATGTTTAATGAAAGGGGAATACACGTTAGAAAGT
ATGCTGCATGAACTGGACGGTCTTATTGAGCAGACCACCGATGGCGTTCCCCTGCAGACTCTAGTGGAATCTCTTCAGGCCTACTTAAGA
AACGCAGCTATGGGACTGGAAGAAGAAACACATGCTCATTACATCGATGTTGCCAGACTACTACATGCTCAGTACGGTGAATTAATCCAA
CCGAGAAATGGTTCAGTTGATGAAACACCCAAAATGTCAGCTGGCCAGATGCTTTTGGTAGCATTCGATGGCATGTTTGCTCAAGTTGAA
ACTGCTTTCAGCTTATTAGTTGAAAAGTTGAACAAGATGGAAATTCCCATAGCTTGGCGAAAGATTGACATCATAAGGGAAGCCAGGAGT
ACTCAAGTTAATTTTTTTGATGATGATAATCACCGGCAGGTGCTAGAAGAGATTTTCTTTCTAAAAAGACTACAGACTATTAAGGAGTTC
TTCAGGCTCTGTGGTACCTTTTCTAAAACATTGTCAGGATCAAGTTCACTTGAAGATCAGAATACTGTGAATGGGCCTGTACAGATTGTC
AATGTGAAAACCCTTTTTAGAAACTCTTGTTTCAGTGAAGACCAAATGGCCAAACCTATCAAGGCATTCACAGCTGACTTTGTGAGGCAG
CTCTTGATAGGGCTACCCAACCAAGCCCTCGGACTCACACTGTGCAGTTTTATCAGTGCTCTGGGTGTAGACATCATTGCTCAAGTAGAG
GCAAAGGACTTTGGTGCCGAAAGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGCGGTGGAACATAACATCCAGATAGGGAAGTTCTCT
CAGCTGGTTATGAACAGGGCAACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAAGAAGCATGACTTGGTGCGAAGGCTAGAAACCAGT
ATTTCTTCTTGTAAGACAAGCCTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCAGTGGCAACATGAAGATCTACTTATCAATAGACCA
CAAGCCATGTCAGTCACACCTCCCCCACGGTCTGCTATCCTAACCAGCATGAAAAAGAAGCTGCATACCCTGAGCCAGATTGAAACTTCT
ATTGCAACAGTTCAGGAGAAGCTAGCTGCACTTGAATCAAGTATTGAACAGCGACTCAAGTGGGCAGGTGGTGCCAACCCTGCATTGGCC
CCTGTACTACAAGATTTTGAAGCAACGATAGCTGAAAGAAGAAATCTTGTCCTTAAAGAGAGCCAAAGAGCAAGTCAGGTCACATTTCTC
TGCAGCAATATCATTCATTTTGAAAGTTTACGAACAAGAACTGCAGAAGCCTTAAACCTGGATGCGGCGTTATTTGAACTAATCAAGCGA
TGTCAGCAGATGTGTTCGTTTGCATCACAGTTTAACAGTTCAGTGTCTGAGTTAGAGCTTCGTTTATTACAGAGAGTGGACACTGGTCTT
GAACATCCTATTGGCAGCTCTGAATGGCTTTTGTCAGCACACAAACAGTTGACCCAGGATATGTCTACTCAGAGGGCAATTCAGACAGAG
AAAGAGCAGCAGATAGAAACGGTCTGTGAAACAATTCAGAATCTGGTTGATAATATAAAGACTGTGCTCACTGGTCATAACCGACAGCTT
GGAGATGTCAAACATCTCTTGAAAGCTATGGCTAAGGATGAAGAAGCTGCTCTGGCAGATGGTGAAGATGTTCCCTATGAGAACAGTGTT
AGGCAGTTTTTGGGTGAATATAAATCATGGCAAGACAACATTCAAACAGTTCTATTTACATTAGTCCAGGCTATGGGTCAGGTTCGAAGT
CAAGAACACGTTGAAATGCTCCAGGAAATCACTCCCACCTTGAAAGAACTGAAAACACAAAGTCAGAGTATCTATAATAATTTAGTGAGT
TTTGCATCACCCTTAGTCACCGATGCAACAAATGAATGTTCGAGTCCAACGTCATCTGCTACTTATCAGCCATCCTTCGCTGCAGCAGTC
CGGAGTAACACTGGCCAGAAGACTCAGCCTGATGTCATGTCACAGAATGCTAGAAAGCTGATCCAAAAAAATCTTGCTACATCAGCTGAT
ACTCCACCAAGCACCGTTCCAGGAACTGGCAAGAGTGTTGCTTGTAGTCCTAAAAAGGCAGTCAGAGACCCTAAAACTGGGAAAGCGGTG
CAAGAGAGAAACTCCTATGCAGTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTTAGAGGGCCGAGATGTTGATCCGAATAGGAGGATGTCA
GTTGCTGAACAGGTTGACTATGTCATTAAGGAAGCAACTAATCTAGATAACTTGGCTCAGCTGTATGAAGGTTGGACAGCCTGGGTGTGA
ATGGCAAGACAGTAGATGAGTCTGGTTAAGCGAGGTCAGACATCCACCAGAATCAACTCAGCCTCAGGCATCCAAAGCCACACCACAGTC
GGTGGTGATGCAACTGGGGGCTTACTCTGAGGAAACCTAGGAAATCTCGGTGCACTAGGAAGTGAATCCCGCAGGACAGCTGCACTCAGG
GATACGCCCAACACCATGGCCTGCAACCCCAGGGTCAAGGGTGAAGGAAAGCAAGCTCACCGCCTGAACACGGAGATTGTCTTTCTGCCA
CAGAACAGCAGCAGACGTGTCGGGAGGTTAGCTGCGGAAAGAAATCGGGATGCCGCGGAGCACAGAGTGATTTGGAACTCCATTCCACCT
GACCCTGTGTGTACAATCCAGGAAAAAAACAAACCCCACTCAGAAACAGAGAAAACTGGGGTCGCGAAGAAATCACAGCCAAGGAAGATT
TGATGCATTCAGATTCTCGTGTAACACTTGTTGCTTGGCAACAGTACTGGTTGGGTTGACCAGTAAGTAGAAAAAGGCTAAAGGCTATGC
GATATGAATTTCAGAAATGGACTGAAAATGGAGAGCTATGTAACAGATACACTACAGTAGAAGAACTTACTTCTGAAATGAAGGGAAAAA
AACCACCCCATCGTTCCCTACTCCTCCCCACCACTTACCCGTTCCCCCTTTACCTAATCTAGTAGATTAGCCATCTTTCAAATTCACTTT
TATTTCAGTCCTTATATTTCATATACTTCCGTCTCGATGCTGTTAACAACTTCTGATAACATGGAAAATTCAAGGATTGTTTAAAGGTCT
GATGATCACACACAAAATGTAATTCCGGTTATTTAAGTCATTTCTGTGATTCTATCATGTACAGTTTCCAGAATTGTCACTGTGCATTCA
AAAGTAATGAATCTAACAGACATTTGATTTAATGTACACTCCCTTTTGCTTATAGTGTGCATTTTTTTTGGAGGTCATTCAAATTTTCCC
TCTTCTGTGATAGCTGTAGTTTCTTTCATAGAAAGTAGCTAATCCAGTGTAATCTTTTACCTTTTTAAAAACCAAGATAGAGTATCTATT
AGAGTTTTACATTGTTGATGATAGATTAACAATAAAGTGATGTTCTGGTGGAGGTAGACTGAAATTTTTTTAATTCATGTTTTTCATTTG
ATACTTTTAATTTACACTTAGTAAATTAAAAGTTGTTTAATTTACTTGGCATTTTAGGACATGTACATGAAACAGTGAAAATGAGATCCA
CCAACATCTTTTATTAAGTTCAGTTATTAGTCTGTGAAGTGCTTTACTTTTTGCACAATTTTAATAGCTTGCTATTCAGTAATACATTAT
AGTGAATTCATGATCAAGGTTTCCTTAAATTTAGCATTGCATTTCAGTACTGACTGTGTAAGCTAAATTGCTGATCCAAAATAAAAACCC
AGACTAGAATAGGGTTCTTAAAATCAAGTATCAATACAAAATAGAACACAATTAAAATCTTAATTGTTGGCTGGGCACAGTGGCTCACGC
CTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCATGAGGTTAGGAGAGCGAGACCATCCTGGCTAACACGGTGAAACCCCGTC
TTTACTAAAAATACAAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGT
GAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGCTAGACTCTGTGTCAAAAATAAA
TGACTAGATAAAAAAAAAAATTGTTTGAGTACATTTTCCCTGCATTTTAGAGATTAGGACAGTGGTCACTTTCTAGTTGCCGTCTTCACA
GACAAACTTGAAAGGTATTAAGGAAAAAATTCCACATAGCTCTGGGCCTTTTTTGTATTCTGATTGCCACGTTAATCTGTAATCGTTAAG
TACCCATGAAAGAATGTGTTTCAGTATCAGTGCTTTTTTGGTACTTTAACAAGTATTGTAGGCACGGTGGATTTTTTTGAAATACCCATG
TGTCCAATAGCAAGTTAAGGAACCTAGCGCATCAAATTTTGTTTTCTTCATTCATTTGGAACCTTATTTTCGCAAAAAACCTAGCTGGAA
TAATAATGCCATATTGTATTTTGCACACTGCTTTATTTTCTAGAGGCTCTGGGAGCAAATTACATTCATCACATTACCTCTGCTCTCTCA
AGATTAAAGTCTTTCAGCAACATTCTTTATTGTCATCATAAGGAAAAACTTTTATCGCAATGATAGTCAGTTCACATTAGTTTAGCACTA
TAGATAGTATTCAGAAATTGCTTTCTCTTTGGTAAAGAAGATAAATAGGTGAATTTTATTGCCTGTGTTTTCAGGCTTCAGAGGTACCTG
GCACCTTACTCAAGCAAAAACAAAAAACAGCTTTACTTCAAAAGCATGTGCCTCTGGTAAATTATCCATCACTTTTGTTTTAAAGTGGTC
CCTCCAAGAATAATGTGGCATACACAGTGGGTTTGGTTGTAAGGCAGATGTAATAGATGACTTCAAAAGCCTGCTCCTTACTGCACTCTG
GACAAGGCCCTGGTCTGTATAGTTTGGCTTCCTCTGTTAAGTCATTCTACAAGGTGACTTGCCATTTGAACTTTCGTAAGAGACCTCAGC
AGTTAGACTGAGAAAAGTTAGAGTGCTGTAGTTATGAAGTCATACATTTTTGATAAAATACCTGTGGAAAACCAGGGATCCTCTCCTGTT
TCTCTCTCTTGCCTCCCCCTTTCCCTCCATTCCTCTGTCGCCTCCCCCTCTCCTCCACTTTCTTTAAGAATCAGGGGGTACAGAATAACC
TACAAACAACCTCTTCAAAGTACCCTTGGAAATTGAAGTTCAATCTTAAGTTTTTTGCTGTCTTTAATTTACTAGAATTGCCTAATTTTT
AGTTGATTTCTCTACAGAGCTTAGCTTGTGTAGTTATTTCTCTTTTACTGTTGCTTTGGTGTGTCTTGAAGTTTGATTGATTATTTTTGG
TCATTGAGTTCTTAGTGTAGTTTGCTAGATGATTATTAAGATTCTTTTGTGTCTGACACTTGTGGTGAGTTGCTTTTGAAATCTGTTGAG
ATTTCCATGTGAGAACTGATAATCAGGCTCTTGATCTGCTTCCCTAAATTACTTTTTTAGAGCCCAAACCCCAGGTTTAGGGTGAGGGTT
TGTAATACAAAGAAACACTTCCATCACTTCTGCCCTTAACCCTTGCCTCTATTACCTAAGCTTAGTAAGTAGTTTTCTTAATATTGTCCA
ATGTTTGGTGTTATCTGCATTGTTTTTTGTTTTTTTAATTGTGGTTGTTCTGACGTGTGAAATTTAAGGAAAGAGCCATTTTTTAAAAAT
GCCGAGCAGGGCAATGCAAGTACAGCCAAATATTAGACTTGATGTGCAATCTTCGGTCCTTTTTAATCTGGGGTATTATAGGCAGTACTT
TAAATTGCAAAGTCTTCCGGGCCTATTTTCCTCTACATTTTTGTAATTAACTCTGGGGGCTTACTTGTTTTGGCAGTACTGAAATCAAAG
GAGCTGGTTCTTCTTTTCTCCCAATTATTTTCATATGAAAGCACCTACAATTAGCCTGTTAGTCCTATTCAGATACATCAAATATCAGTG
AATGCTTTACTATTCGCACATTTAAGCATCTTTGTTTTACATAAAATTAGAGTATGAAAACCAGTGTTCAATTTTTTATCTTGTTGAGCT
TGTAAAATGCCAGCAATTTAAAACTAGGACTTTTCCCCCCATAAGCCAAGGAGGTAGAATTACTAATACAAGGGTTAAAGAAGGTAGATT
TTGTTTTCAATATTTGGGTAATATTAGAAAGATTCTTCCCACAGGGAAGAACTAGCAAGTGTCCCAATTTTTTCCAAACGTTGGGGAGGG
GAAAATTCACTGTATCATGAAACCCTAAGGGTTTGTTGCACTTCCTGCTTTTTAGGCCTGGATAACAGTATCACCATCCTTATTTACAGA
AGGGTAAAACTGACTCTTAATGAGAAAAGCTTTATAAGTTCAAGGGCTGTAAAATATGAACTACTTAGGGTCGTTTGCCTTCCATGGGAA
CTTGGCTAGACTTAGAAAAAGCTGTTTGTTGTGCTAATGTAAAAGTGTCATACAATTTAGAAGATTTTTGAAGATGGTAAACTTAGAAGA
ATTCTATGTTCTGAAATGCACACTTTTAGAATGTTTTTCTTTGAAAACAGGCTAATAGTTTTTTCTTTTTTTGACAAAGTTTCAGCTCCT
CTTTAAAGTTATTGTGTCATTTTTCTGGTTTAAATTTCCCTTATATTTCCACCTGTAATGTCAGTGGCAACAACATCATACTTCACTTAC
TTGTTAATTTACTTTTTACCCTTATTCTAAGAGCAAGTTGAGTTGAACTGAATCTTCCTTGTCTTAGTAACAATGTATAAATAGTGGCTT
TTCTGTACAAAAGGTTGTAATGCCTCCTGATGGATATAATTTTGTGATTGTATTTAAAAGTTGAATAAATCACACCAGCTTCCTGAAAAT
GTTCATAATGCATCTTTTGGAAAACAAATACATGCCTACTTTGTGCATATTTGCATTAACATGGCAAAGATTGTATGAAATACCTGTTTT

>5042_5042_2_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000332680_SMG1_chr16_18883946_ENST00000446231_length(amino acids)=3245AA_BP=214
MGRQLAGCGDAGKKASFKMSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIA
FAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISD
TSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSS
SPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNIC
LQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVI
SFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLN
PDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAV
TVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVD
CCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKA
DFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSI
TENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQL
LEKIKEQTVPIRSHLMELGLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQ
STHAMEMLSSCAISFCKSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIES
ESTVHIGVGEPDFILGQLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQA
VCRPAGIQDEDITLQITESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDE
DDPRLHLSHRVEQSTDDMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLI
LYPAIVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVL
QVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPH
EKWFQDNYGDAIENALEKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGG
TITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFG
LYKRWQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTT
PDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSC
EQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLP
KLDGSLDEYLSLQEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEA
TQLASLLQEISTQMDLGPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWKT
WMEELICNTTVERCQELYRKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHEN
GEEGSLSLASVIISALCTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVHL
ANGVYTSLQELNSNFRQIIFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQ
YGELIQPRNGSVDETPKMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKRL
QTIKEFFRLCGTFSKTLSGSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVD
IIAQVEAKDFGAESKVSVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQWQHED
LLINRPQAMSVTPPPRSAILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRA
SQVTFLCSNIIHFESLRTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMSTQ
RAIQTEKEQQIETVCETIQNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQA
MGQVRSQEHVEMLQEITPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQKN
LATSADTPPSTVPGTGKSVACSPKKAVRDPKTGKAVQERNSYAVSVWKRVKAKLEGRDVDPNRRMSVAEQVDYVIKEATNLDNLAQLYEG

--------------------------------------------------------------
>5042_5042_3_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000396024_SMG1_chr16_18883946_ENST00000389467_length(transcript)=14563nt_BP=748nt
GCTCAGCATTTGGGGACGCTCTCAGCTCTCGGCGCACGGCCCAGGGTGAAAATGTTTGCCATTAAACTCACATGAAGTAGGAAATATTTA
TATGGATACAAAAGGCACCTGCATGGGATAATGTCAAATTTCATAGATACTGCTTTGTGCTTCCTTCAAAATGTCTACTGTTCACGAAAT
CCTGTGCAAGCTCAGCTTGGAGGGTGATCACTCTACACCCCCAAGTGCATATGGGTCTGTCAAAGCCTATACTAACTTTGATGCTGAGCG
GGATGCTTTGAACATTGAAACAGCCATCAAGACCAAAGGTGTGGATGAGGTCACCATTGTCAACATTTTGACCAACCGCAGCAATGCACA
GAGACAGGATATTGCCTTCGCCTACCAGAGAAGGACCAAAAAGGAACTTGCATCAGCACTGAAGTCAGCCTTATCTGGCCACCTGGAGAC
GGTGATTTTGGGCCTATTGAAGACACCTGCTCAGTATGACGCTTCTGAGCTAAAAGCTTCCATGAAGGGGCTGGGAACCGACGAGGACTC
TCTCATTGAGATCATCTGCTCCAGAACCAACCAGGAGCTGCAGGAAATTAACAGAGTCTACAAGGAAATGTACAAGACTGATCTGGAGAA
GGACATTATTTCGGACACATCTGGTGACTTCCGCAAGCTGATGGTTGCCCTGGCAAAGGGTAGAAGAGCAGAGGATGGCTCTGTCATTGA
TTATGAACTGATTGACCAAGATGCTCGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAG
TGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAG
TAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATT
AAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTT
AATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGA
AGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGT
TTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAG
CAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGA
TTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCA
GAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGC
ACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGC
AGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGT
TCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGT
CATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGC
AGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGT
AACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGG
AAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGC
CATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACA
TTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATG
TGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTC
CCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATT
GTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGA
TCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCA
GAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAAC
AGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGA
GGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTAT
GTACCAGAATCAGTTGTTGGAGAAAATTAAAGAACAAACAGTCCCAATTAGAAGCCATCTCATGGAATTAGGTCTAACAGCAGCAAAATT
TGCTAGAAAACGAGGGAATGTGTCCCTTGCAACAAGACTGCTGGCACAGTGCAGTGAAGTTCAGCTGGGAAAGACCACCACTGCACAGGA
TTTAGTCCAACATTTTAAAAAACTATCAACCCAAGGTCAAGTGGATGAAAAATGGGGGCCCGAACTTGATATTGAAAAAACCAAATTGCT
TTATACAGCAGGCCAGTCAACACATGCAATGGAAATGTTGAGTTCTTGTGCCATATCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGT
TGCTAAATCAATTCTGACACTGGCTAAATGGATCCAGGCAGAATGGAAAGAGATTTCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCA
CCAACAGAACTTCACAGGTCTTTCTACTTTGTCTAAAAACATACTCACTCTAATAGAACTGCCATCTGTTAATACGATGGAAGAAGAGTA
TCCTCGGATCGAGAGTGAATCTACAGTGCATATTGGAGTTGGAGAACCTGACTTCATTTTGGGACAGTTGTATCACCTGTCTTCAGTACA
GGCACCTGAAGTAGCCAAATCTTGGGCAGCGTTGGCCAGCTGGGCTTATAGGTGGGGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGA
AGGTGTTCGTCTGCTGCCTAGAGAAAAATCTGAAGTTCAGAATCTACTTCCAGACACTATAACTGAGGAAGAGAAAGAGAGAATATATGG
TATTCTTGGACAGGCTGTGTGTCGGCCGGCGGGGATTCAGGATGAAGATATAACACTTCAGATAACTGAGAGTGAAGACAACGAAGAAGA
TGACATGGTTGATGTTATCTGGCGTCAGTTGATATCAAGCTGCCCATGGCTTTCAGAACTTGATGAAAGTGCAACTGAAGGAGTTATTAA
AGTGTGGAGGAAAGTTGTAGATAGAATATTCAGCCTGTACAAACTCTCTTGCAGTGCATACTTTACTTTCCTTAAACTCAACGCTGGTCA
AATTCCTTTAGATGAGGATGACCCTAGGCTGCATTTAAGTCACAGAGTGGAACAGAGCACTGATGACATGATTGTGATGGCCACATTGCG
CCTGCTGCGGTTGCTCGTGAAGCATGCTGGTGAGCTTCGGCAGTATCTGGAGCACGGCTTGGAGACAACACCCACTGCACCATGGAGAGG
AATTATTCCGCAACTTTTCTCACGCTTAAACCACCCTGAAGTGTATGTGCGCCAAAGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGA
TTCCCCACATCTCATATTGTATCCTGCAATAGTGGGTACCATATCGCTTAGTAGTGAATCCCAGGCTTCAGGAAATAAATTTTCCACTGC
AATTCCAACTTTACTTGGCAATATTCAAGGAGAAGAATTGCTGGTTTCTGAATGTGAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAA
TAAGGATGAACCTAAAAGTGGATTAAATGAAGACCAAGCCATGATGCAGGATTGTTACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAA
CCCCACCATGGTATTACAGGTTCAGATGCTCGTGGCTGAACTGCGCAGGGTCACTGTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCT
GCAACAACACATGTATGTCCTGAGACGAATTCAGCAGCTTGAAGATGAGGTGAAGAGAGTCCAGAACAACAACACCTTACGCAAAGAAGA
GAAAATTGCAATCATGAGGGAGAAGCACACAGCTTTGATGAAGCCCATCGTATTTGCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCC
TGCAGAAACACCTCATGAAAAATGGTTTCAGGATAACTATGGTGATGCCATTGAAAATGCCCTAGAAAAACTGAAGACTCCATTGAACCC
TGCAAAGCCTGGGAGCAGCTGGATTCCATTTAAAGAGATAATGCTAAGTTTGCAACAGAGAGCACAGAAACGTGCAAGTTACATCTTGCG
TCTTGAAGAAATCAGTCCATGGTTGGCTGCCATGACTAACACTGAAATTGCTCTTCCTGGGGAAGTCTCAGCCAGAGACACTGTCACAAT
CCATAGTGTGGGCGGAACCATCACAATCTTACCGACTAAAACCAAGCCAAAGAAACTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCC
TTATCTTTTCAAAGGACTGGAGGATTTACATCTGGATGAGAGAATAATGCAGTTCCTATCTATTGTGAATACCATGTTTGCTACAATTAA
TCGCCAAGAAACACCCCGGTTCCATGCTCGACACTATTCTGTAACACCACTAGGAACAAGATCAGGACTAATCCAGTGGGTAGATGGAGC
CACACCCTTATTTGGTCTTTACAAACGATGGCAACAACGGGAAGCTGCCTTACAAGCACAAAAGGCCCAAGATTCCTACCAAACTCCTCA
GAATCCTGGAATTGTACCCCGTCCTAGTGAACTTTATTACAGTAAAATTGGCCCTGCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTC
CCGTCGGGATTGGCCTCTTCATGTAATGAAGGCAGTATTGGAAGAGTTAATGGAGGCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTG
GTCATCTTGCACAACACCTGATGAATGGTGGAGAGTTACGCAGTCTTATGCAAGATCTACTGCAGTCATGTCTATGGTTGGATACATAAT
TGGCCTTGGAGACAGACATCTGGATAATGTTCTTATAGATATGACGACTGGAGAAGTTGTTCACATAGATTACAATGTTTGCTTTGAAAA
AGGTAAAAGCCTTAGAGTTCCTGAGAAAGTACCTTTTCGAATGACACAAAACATTGAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGT
ATTTAGGCTTTCATGTGAGCAGGTTTTACACATTATGCGGCGTGGCAGAGAGACCCTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCC
TCTGGTGGACTGGACAGCAGGAGGCGAGGCTGGGTTTGCTGGTGCTGTCTATGGTGGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAA
GAGAGAGATGGAGCGAGAGATCACCCGCAGCCTGTTTTCTTCTAGAGTAGCTGAGATTAAGGTGAACTGGTTTAAGAATAGAGATGAGAT
GCTGGTTGTGCTTCCCAAGTTGGACGGTAGCTTAGATGAATACCTAAGCTTGCAAGAGCAACTGACAGATGTGGAAAAACTGCAGGGCAA
ACTACTGGAGGAAATAGAGTTTCTAGAAGGAGCTGAAGGGGTGGATCATCCTTCTCATACTCTGCAACACAGGTATTCTGAGCACACCCA
ACTACAGACTCAGCAAAGAGCTGTTCAGGAAGCAATCCAGGTGAAGCTGAATGAATTTGAACAATGGATAACACATTATCAGGCTGCATT
CAATAATTTAGAAGCAACACAGCTTGCAAGCTTGCTTCAAGAGATAAGCACACAAATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAAC
AGCCTTTCTGCAGAATGCTGGTCAGGCCCACTTGATTAGCCAGTGCGAGCAGCTGGAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCG
CTCCGTGCTCCGTGGCTGTCTGGAGCAACTGCATCACTATGCAACCGTGGCCCTGCAGTATCCGAAGGCCATATTTCAGAAACATCGAAT
TGAACAGTGGAAGACCTGGATGGAAGAGCTCATCTGTAACACCACAGTAGAGCGTTGTCAAGAGCTCTATAGGAAATATGAAATGCAATA
TGCTCCCCAGCCACCCCCAACAGTGTGTCAGTTCATCACTGCCACTGAAATGACCCTGCAGCGATACGCAGCAGACATCAACAGCAGACT
TATTAGACAAGTGGAACGCTTGAAACAGGAAGCTGTCACTGTGCCAGTTTGTGAAGATCAGTTGAAAGAAATTGAACGTTGCATTAAAGT
TTTCCTTCATGAGAATGGAGAAGAAGGATCTTTGAGTCTAGCAAGTGTTATTATTTCTGCCCTTTGTACCCTTACAAGGCGTAACCTGAT
GATGGAAGGTGCAGCGTCAAGTGCTGGAGAACAGCTGGTTGATCTGACTTCTCGGGATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTAT
GAGCGGAAACGTCACCTGCTTGGTTCAGTTACTGAAGCAGTGCCACCTGGTGCCACAGGACTTAGATATCCCGAACCCCATGGAAGCGTC
TGAGACAGTTCACTTAGCCAATGGAGTGTATACCTCACTTCAGGAATTGAATTCGAATTTCCGGCAAATCATATTTCCAGAAGCACTTCG
ATGTTTAATGAAAGGGGAATACACGTTAGAAAGTATGCTGCATGAACTGGACGGTCTTATTGAGCAGACCACCGATGGCGTTCCCCTGCA
GACTCTAGTGGAATCTCTTCAGGCCTACTTAAGAAACGCAGCTATGGGACTGGAAGAAGAAACACATGCTCATTACATCGATGTTGCCAG
ACTACTACATGCTCAGTACGGTGAATTAATCCAACCGAGAAATGGTTCAGTTGATGAAACACCCAAAATGTCAGCTGGCCAGATGCTTTT
GGTAGCATTCGATGGCATGTTTGCTCAAGTTGAAACTGCTTTCAGCTTATTAGTTGAAAAGTTGAACAAGATGGAAATTCCCATAGCTTG
GCGAAAGATTGACATCATAAGGGAAGCCAGGAGTACTCAAGTTAATTTTTTTGATGATGATAATCACCGGCAGGTGCTAGAAGAGATTTT
CTTTCTAAAAAGACTACAGACTATTAAGGAGTTCTTCAGGCTCTGTGGTACCTTTTCTAAAACATTGTCAGGATCAAGTTCACTTGAAGA
TCAGAATACTGTGAATGGGCCTGTACAGATTGTCAATGTGAAAACCCTTTTTAGAAACTCTTGTTTCAGTGAAGACCAAATGGCCAAACC
TATCAAGGCATTCACAGCTGACTTTGTGAGGCAGCTCTTGATAGGGCTACCCAACCAAGCCCTCGGACTCACACTGTGCAGTTTTATCAG
TGCTCTGGGTGTAGACATCATTGCTCAAGTAGAGGCAAAGGACTTTGGTGCCGAAAGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGC
GGTGGAACATAACATCCAGATAGGGAAGTTCTCTCAGCTGGTTATGAACAGGGCAACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAA
GAAGCATGACTTGGTGCGAAGGCTAGAAACCAGTATTTCTTCTTGTAAGACAAGCCTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCA
GCAGTGGCAACATGAAGATCTACTTATCAATAGACCACAAGCCATGTCAGTCACACCTCCCCCACGGTCTGCTATCCTAACCAGCATGAA
AAAGAAGCTGCATACCCTGAGCCAGATTGAAACTTCTATTGCAACAGTTCAGGAGAAGCTAGCTGCACTTGAATCAAGTATTGAACAGCG
ACTCAAGTGGGCAGGTGGTGCCAACCCTGCATTGGCCCCTGTACTACAAGATTTTGAAGCAACGATAGCTGAAAGAAGAAATCTTGTCCT
TAAAGAGAGCCAAAGAGCAAGTCAGGTCACATTTCTCTGCAGCAATATCATTCATTTTGAAAGTTTACGAACAAGAACTGCAGAAGCCTT
AAACCTGGATGCGGCGTTATTTGAACTAATCAAGCGATGTCAGCAGATGTGTTCGTTTGCATCACAGTTTAACAGTTCAGTGTCTGAGTT
AGAGCTTCGTTTATTACAGAGAGTGGACACTGGTCTTGAACATCCTATTGGCAGCTCTGAATGGCTTTTGTCAGCACACAAACAGTTGAC
CCAGGATATGTCTACTCAGAGGGCAATTCAGACAGAGAAAGAGCAGCAGATAGAAACGGTCTGTGAAACAATTCAGAATCTGGTTGATAA
TATAAAGACTGTGCTCACTGGTCATAACCGACAGCTTGGAGATGTCAAACATCTCTTGAAAGCTATGGCTAAGGATGAAGAAGCTGCTCT
GGCAGATGGTGAAGATGTTCCCTATGAGAACAGTGTTAGGCAGTTTTTGGGTGAATATAAATCATGGCAAGACAACATTCAAACAGTTCT
ATTTACATTAGTCCAGGCTATGGGTCAGGTTCGAAGTCAAGAACACGTTGAAATGCTCCAGGAAATCACTCCCACCTTGAAAGAACTGAA
AACACAAAGTCAGAGTATCTATAATAATTTAGTGAGTTTTGCATCACCCTTAGTCACCGATGCAACAAATGAATGTTCGAGTCCAACGTC
ATCTGCTACTTATCAGCCATCCTTCGCTGCAGCAGTCCGGAGTAACACTGGCCAGAAGACTCAGCCTGATGTCATGTCACAGAATGCTAG
AAAGCTGATCCAAAAAAATCTTGCTACATCAGCTGATACTCCACCAAGCACCGTTCCAGGAACTGGCAAGAGTGTTGCTTGTAGTCCTAA
AAAGGCAGTCAGAGACCCTAAAACTGGGAAAGCGGTGCAAGAGAGAAACTCCTATGCAGTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTT
AGAGGGCCGAGATGTTGATCCGAATAGGAGGATGTCAGTTGCTGAACAGGTTGACTATGTCATTAAGGAAGCAACTAATCTAGATAACTT
GGCTCAGCTGTATGAAGGTTGGACAGCCTGGGTGTGAATGGCAAGACAGTAGATGAGTCTGGTTAAGCGAGGTCAGACATCCACCAGAAT
CAACTCAGCCTCAGGCATCCAAAGCCACACCACAGTCGGTGGTGATGCAACTGGGGGCTTACTCTGAGGAAACCTAGGAAATCTCGGTGC
ACTAGGAAGTGAATCCCGCAGGACAGCTGCACTCAGGGATACGCCCAACACCATGGCCTGCAACCCCAGGGTCAAGGGTGAAGGAAAGCA
AGCTCACCGCCTGAACACGGAGATTGTCTTTCTGCCACAGAACAGCAGCAGACGTGTCGGGAGGTTAGCTGCGGAAAGAAATCGGGATGC
CGCGGAGCACAGAGTGATTTGGAACTCCATTCCACCTGACCCTGTGTGTACAATCCAGGAAAAAAACAAACCCCACTCAGAAACAGAGAA
AACTGGGGTCGCGAAGAAATCACAGCCAAGGAAGATTTGATGCATTCAGATTCTCGTGTAACACTTGTTGCTTGGCAACAGTACTGGTTG
GGTTGACCAGTAAGTAGAAAAAGGCTAAAGGCTATGCGATATGAATTTCAGAAATGGACTGAAAATGGAGAGCTATGTAACAGATACACT
ACAGTAGAAGAACTTACTTCTGAAATGAAGGGAAAAAAACCACCCCATCGTTCCCTACTCCTCCCCACCACTTACCCGTTCCCCCTTTAC
CTAATCTAGTAGATTAGCCATCTTTCAAATTCACTTTTATTTCAGTCCTTATATTTCATATACTTCCGTCTCGATGCTGTTAACAACTTC
TGATAACATGGAAAATTCAAGGATTGTTTAAAGGTCTGATGATCACACACAAAATGTAATTCCGGTTATTTAAGTCATTTCTGTGATTCT
ATCATGTACAGTTTCCAGAATTGTCACTGTGCATTCAAAAGTAATGAATCTAACAGACATTTGATTTAATGTACACTCCCTTTTGCTTAT
AGTGTGCATTTTTTTTGGAGGTCATTCAAATTTTCCCTCTTCTGTGATAGCTGTAGTTTCTTTCATAGAAAGTAGCTAATCCAGTGTAAT
CTTTTACCTTTTTAAAAACCAAGATAGAGTATCTATTAGAGTTTTACATTGTTGATGATAGATTAACAATAAAGTGATGTTCTGGTGGAG
GTAGACTGAAATTTTTTTAATTCATGTTTTTCATTTGATACTTTTAATTTACACTTAGTAAATTAAAAGTTGTTTAATTTACTTGGCATT
TTAGGACATGTACATGAAACAGTGAAAATGAGATCCACCAACATCTTTTATTAAGTTCAGTTATTAGTCTGTGAAGTGCTTTACTTTTTG
CACAATTTTAATAGCTTGCTATTCAGTAATACATTATAGTGAATTCATGATCAAGGTTTCCTTAAATTTAGCATTGCATTTCAGTACTGA
CTGTGTAAGCTAAATTGCTGATCCAAAATAAAAACCCAGACTAGAATAGGGTTCTTAAAATCAAGTATCAATACAAAATAGAACACAATT
AAAATCTTAATTGTTGGCTGGGCACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCATGAGGTTAGGAG
AGCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTTTACTAAAAATACAAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGT
CCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAG
CCTGGGCAACAGAGCTAGACTCTGTGTCAAAAATAAATGACTAGATAAAAAAAAAAATTGTTTGAGTACATTTTCCCTGCATTTTAGAGA
TTAGGACAGTGGTCACTTTCTAGTTGCCGTCTTCACAGACAAACTTGAAAGGTATTAAGGAAAAAATTCCACATAGCTCTGGGCCTTTTT
TGTATTCTGATTGCCACGTTAATCTGTAATCGTTAAGTACCCATGAAAGAATGTGTTTCAGTATCAGTGCTTTTTTGGTACTTTAACAAG
TATTGTAGGCACGGTGGATTTTTTTGAAATACCCATGTGTCCAATAGCAAGTTAAGGAACCTAGCGCATCAAATTTTGTTTTCTTCATTC
ATTTGGAACCTTATTTTCGCAAAAAACCTAGCTGGAATAATAATGCCATATTGTATTTTGCACACTGCTTTATTTTCTAGAGGCTCTGGG
AGCAAATTACATTCATCACATTACCTCTGCTCTCTCAAGATTAAAGTCTTTCAGCAACATTCTTTATTGTCATCATAAGGAAAAACTTTT
ATCGCAATGATAGTCAGTTCACATTAGTTTAGCACTATAGATAGTATTCAGAAATTGCTTTCTCTTTGGTAAAGAAGATAAATAGGTGAA
TTTTATTGCCTGTGTTTTCAGGCTTCAGAGGTACCTGGCACCTTACTCAAGCAAAAACAAAAAACAGCTTTACTTCAAAAGCATGTGCCT
CTGGTAAATTATCCATCACTTTTGTTTTAAAGTGGTCCCTCCAAGAATAATGTGGCATACACAGTGGGTTTGGTTGTAAGGCAGATGTAA
TAGATGACTTCAAAAGCCTGCTCCTTACTGCACTCTGGACAAGGCCCTGGTCTGTATAGTTTGGCTTCCTCTGTTAAGTCATTCTACAAG
GTGACTTGCCATTTGAACTTTCGTAAGAGACCTCAGCAGTTAGACTGAGAAAAGTTAGAGTGCTGTAGTTATGAAGTCATACATTTTTGA
TAAAATACCTGTGGAAAACCAGGGATCCTCTCCTGTTTCTCTCTCTTGCCTCCCCCTTTCCCTCCATTCCTCTGTCGCCTCCCCCTCTCC
TCCACTTTCTTTAAGAATCAGGGGGTACAGAATAACCTACAAACAACCTCTTCAAAGTACCCTTGGAAATTGAAGTTCAATCTTAAGTTT
TTTGCTGTCTTTAATTTACTAGAATTGCCTAATTTTTAGTTGATTTCTCTACAGAGCTTAGCTTGTGTAGTTATTTCTCTTTTACTGTTG
CTTTGGTGTGTCTTGAAGTTTGATTGATTATTTTTGGTCATTGAGTTCTTAGTGTAGTTTGCTAGATGATTATTAAGATTCTTTTGTGTC
TGACACTTGTGGTGAGTTGCTTTTGAAATCTGTTGAGATTTCCATGTGAGAACTGATAATCAGGCTCTTGATCTGCTTCCCTAAATTACT
TTTTTAGAGCCCAAACCCCAGGTTTAGGGTGAGGGTTTGTAATACAAAGAAACACTTCCATCACTTCTGCCCTTAACCCTTGCCTCTATT
ACCTAAGCTTAGTAAGTAGTTTTCTTAATATTGTCCAATGTTTGGTGTTATCTGCATTGTTTTTTGTTTTTTTAATTGTGGTTGTTCTGA
CGTGTGAAATTTAAGGAAAGAGCCATTTTTTAAAAATGCCGAGCAGGGCAATGCAAGTACAGCCAAATATTAGACTTGATGTGCAATCTT
CGGTCCTTTTTAATCTGGGGTATTATAGGCAGTACTTTAAATTGCAAAGTCTTCCGGGCCTATTTTCCTCTACATTTTTGTAATTAACTC
TGGGGGCTTACTTGTTTTGGCAGTACTGAAATCAAAGGAGCTGGTTCTTCTTTTCTCCCAATTATTTTCATATGAAAGCACCTACAATTA
GCCTGTTAGTCCTATTCAGATACATCAAATATCAGTGAATGCTTTACTATTCGCACATTTAAGCATCTTTGTTTTACATAAAATTAGAGT
ATGAAAACCAGTGTTCAATTTTTTATCTTGTTGAGCTTGTAAAATGCCAGCAATTTAAAACTAGGACTTTTCCCCCCATAAGCCAAGGAG
GTAGAATTACTAATACAAGGGTTAAAGAAGGTAGATTTTGTTTTCAATATTTGGGTAATATTAGAAAGATTCTTCCCACAGGGAAGAACT
AGCAAGTGTCCCAATTTTTTCCAAACGTTGGGGAGGGGAAAATTCACTGTATCATGAAACCCTAAGGGTTTGTTGCACTTCCTGCTTTTT
AGGCCTGGATAACAGTATCACCATCCTTATTTACAGAAGGGTAAAACTGACTCTTAATGAGAAAAGCTTTATAAGTTCAAGGGCTGTAAA
ATATGAACTACTTAGGGTCGTTTGCCTTCCATGGGAACTTGGCTAGACTTAGAAAAAGCTGTTTGTTGTGCTAATGTAAAAGTGTCATAC
AATTTAGAAGATTTTTGAAGATGGTAAACTTAGAAGAATTCTATGTTCTGAAATGCACACTTTTAGAATGTTTTTCTTTGAAAACAGGCT
AATAGTTTTTTCTTTTTTTGACAAAGTTTCAGCTCCTCTTTAAAGTTATTGTGTCATTTTTCTGGTTTAAATTTCCCTTATATTTCCACC
TGTAATGTCAGTGGCAACAACATCATACTTCACTTACTTGTTAATTTACTTTTTACCCTTATTCTAAGAGCAAGTTGAGTTGAACTGAAT
CTTCCTTGTCTTAGTAACAATGTATAAATAGTGGCTTTTCTGTACAAAAGGTTGTAATGCCTCCTGATGGATATAATTTTGTGATTGTAT
TTAAAAGTTGAATAAATCACACCAGCTTCCTGAAAATGTTCATAATGCATCTTTTGGAAAACAAATACATGCCTACTTTGTGCATATTTG

>5042_5042_3_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000396024_SMG1_chr16_18883946_ENST00000389467_length(amino acids)=3235AA_BP=203
MLCASFKMSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKEL
ASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVA
LAKGRRAEDGSVIDYELIDQDARMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVIS
TVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALS
SSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRT
GKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTA
DNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTE
MKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVL
TLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSF
ESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQT
SRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKEQTVPI
RSHLMELGLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSSC
AISFCKSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIESESTVHIGVGEP
DFILGQLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDED
ITLQITESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRV
EQSTDDMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISL
SSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRR
VTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDA
IENALEKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKP
KKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA
LQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSY
ARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGR
ETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLS
LQEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEATQLASLLQEIS
TQMDLGPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWKTWMEELICNTTV
ERCQELYRKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHENGEEGSLSLASV
IISALCTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVHLANGVYTSLQEL
NSNFRQIIFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQYGELIQPRNGS
VDETPKMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKRLQTIKEFFRLCG
TFSKTLSGSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVDIIAQVEAKDFG
AESKVSVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQQWQHEDLLINRPQAMS
VTPPPRSAILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRASQVTFLCSNI
IHFESLRTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMSTQRAIQTEKEQQ
IETVCETIQNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQAMGQVRSQEHV
EMLQEITPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQKNLATSADTPPS

--------------------------------------------------------------
>5042_5042_4_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000396024_SMG1_chr16_18883946_ENST00000446231_length(transcript)=14560nt_BP=748nt
GCTCAGCATTTGGGGACGCTCTCAGCTCTCGGCGCACGGCCCAGGGTGAAAATGTTTGCCATTAAACTCACATGAAGTAGGAAATATTTA
TATGGATACAAAAGGCACCTGCATGGGATAATGTCAAATTTCATAGATACTGCTTTGTGCTTCCTTCAAAATGTCTACTGTTCACGAAAT
CCTGTGCAAGCTCAGCTTGGAGGGTGATCACTCTACACCCCCAAGTGCATATGGGTCTGTCAAAGCCTATACTAACTTTGATGCTGAGCG
GGATGCTTTGAACATTGAAACAGCCATCAAGACCAAAGGTGTGGATGAGGTCACCATTGTCAACATTTTGACCAACCGCAGCAATGCACA
GAGACAGGATATTGCCTTCGCCTACCAGAGAAGGACCAAAAAGGAACTTGCATCAGCACTGAAGTCAGCCTTATCTGGCCACCTGGAGAC
GGTGATTTTGGGCCTATTGAAGACACCTGCTCAGTATGACGCTTCTGAGCTAAAAGCTTCCATGAAGGGGCTGGGAACCGACGAGGACTC
TCTCATTGAGATCATCTGCTCCAGAACCAACCAGGAGCTGCAGGAAATTAACAGAGTCTACAAGGAAATGTACAAGACTGATCTGGAGAA
GGACATTATTTCGGACACATCTGGTGACTTCCGCAAGCTGATGGTTGCCCTGGCAAAGGGTAGAAGAGCAGAGGATGGCTCTGTCATTGA
TTATGAACTGATTGACCAAGATGCTCGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAG
TGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAG
TAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATT
AAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTT
AATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGA
AGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGT
TTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAG
CAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGA
TTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCA
GAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGC
ACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGC
AGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGT
TCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGT
CATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGC
AGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGT
AACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGG
AAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGC
CATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACA
TTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATG
TGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTC
CCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATT
GTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGA
TCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCA
GAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAAC
AGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGA
GGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTAT
GTACCAGAATCAGTTGTTGGAGAAAATTAAAGAACAAACAGTCCCAATTAGAAGCCATCTCATGGAATTAGGTCTAACAGCAGCAAAATT
TGCTAGAAAACGAGGGAATGTGTCCCTTGCAACAAGACTGCTGGCACAGTGCAGTGAAGTTCAGCTGGGAAAGACCACCACTGCACAGGA
TTTAGTCCAACATTTTAAAAAACTATCAACCCAAGGTCAAGTGGATGAAAAATGGGGGCCCGAACTTGATATTGAAAAAACCAAATTGCT
TTATACAGCAGGCCAGTCAACACATGCAATGGAAATGTTGAGTTCTTGTGCCATATCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGT
TGCTAAATCAATTCTGACACTGGCTAAATGGATCCAGGCAGAATGGAAAGAGATTTCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCA
CCAACAGAACTTCACAGGTCTTTCTACTTTGTCTAAAAACATACTCACTCTAATAGAACTGCCATCTGTTAATACGATGGAAGAAGAGTA
TCCTCGGATCGAGAGTGAATCTACAGTGCATATTGGAGTTGGAGAACCTGACTTCATTTTGGGACAGTTGTATCACCTGTCTTCAGTACA
GGCACCTGAAGTAGCCAAATCTTGGGCAGCGTTGGCCAGCTGGGCTTATAGGTGGGGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGA
AGGTGTTCGTCTGCTGCCTAGAGAAAAATCTGAAGTTCAGAATCTACTTCCAGACACTATAACTGAGGAAGAGAAAGAGAGAATATATGG
TATTCTTGGACAGGCTGTGTGTCGGCCGGCGGGGATTCAGGATGAAGATATAACACTTCAGATAACTGAGAGTGAAGACAACGAAGAAGA
TGACATGGTTGATGTTATCTGGCGTCAGTTGATATCAAGCTGCCCATGGCTTTCAGAACTTGATGAAAGTGCAACTGAAGGAGTTATTAA
AGTGTGGAGGAAAGTTGTAGATAGAATATTCAGCCTGTACAAACTCTCTTGCAGTGCATACTTTACTTTCCTTAAACTCAACGCTGGTCA
AATTCCTTTAGATGAGGATGACCCTAGGCTGCATTTAAGTCACAGAGTGGAACAGAGCACTGATGACATGATTGTGATGGCCACATTGCG
CCTGCTGCGGTTGCTCGTGAAGCATGCTGGTGAGCTTCGGCAGTATCTGGAGCACGGCTTGGAGACAACACCCACTGCACCATGGAGAGG
AATTATTCCGCAACTTTTCTCACGCTTAAACCACCCTGAAGTGTATGTGCGCCAAAGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGA
TTCCCCACATCTCATATTGTATCCTGCAATAGTGGGTACCATATCGCTTAGTAGTGAATCCCAGGCTTCAGGAAATAAATTTTCCACTGC
AATTCCAACTTTACTTGGCAATATTCAAGGAGAAGAATTGCTGGTTTCTGAATGTGAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAA
TAAGGATGAACCTAAAAGTGGATTAAATGAAGACCAAGCCATGATGCAGGATTGTTACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAA
CCCCACCATGGTATTACAGGTTCAGATGCTCGTGGCTGAACTGCGCAGGGTCACTGTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCT
GCAACAACACATGTATGTCCTGAGACGAATTCAGCAGCTTGAAGATGAGGTGAAGAGAGTCCAGAACAACAACACCTTACGCAAAGAAGA
GAAAATTGCAATCATGAGGGAGAAGCACACAGCTTTGATGAAGCCCATCGTATTTGCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCC
TGCAGAAACACCTCATGAAAAATGGTTTCAGGATAACTATGGTGATGCCATTGAAAATGCCCTAGAAAAACTGAAGACTCCATTGAACCC
TGCAAAGCCTGGGAGCAGCTGGATTCCATTTAAAGAGATAATGCTAAGTTTGCAACAGAGAGCACAGAAACGTGCAAGTTACATCTTGCG
TCTTGAAGAAATCAGTCCATGGTTGGCTGCCATGACTAACACTGAAATTGCTCTTCCTGGGGAAGTCTCAGCCAGAGACACTGTCACAAT
CCATAGTGTGGGCGGAACCATCACAATCTTACCGACTAAAACCAAGCCAAAGAAACTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCC
TTATCTTTTCAAAGGACTGGAGGATTTACATCTGGATGAGAGAATAATGCAGTTCCTATCTATTGTGAATACCATGTTTGCTACAATTAA
TCGCCAAGAAACACCCCGGTTCCATGCTCGACACTATTCTGTAACACCACTAGGAACAAGATCAGGACTAATCCAGTGGGTAGATGGAGC
CACACCCTTATTTGGTCTTTACAAACGATGGCAACAACGGGAAGCTGCCTTACAAGCACAAAAGGCCCAAGATTCCTACCAAACTCCTCA
GAATCCTGGAATTGTACCCCGTCCTAGTGAACTTTATTACAGTAAAATTGGCCCTGCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTC
CCGTCGGGATTGGCCTCTTCATGTAATGAAGGCAGTATTGGAAGAGTTAATGGAGGCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTG
GTCATCTTGCACAACACCTGATGAATGGTGGAGAGTTACGCAGTCTTATGCAAGATCTACTGCAGTCATGTCTATGGTTGGATACATAAT
TGGCCTTGGAGACAGACATCTGGATAATGTTCTTATAGATATGACGACTGGAGAAGTTGTTCACATAGATTACAATGTTTGCTTTGAAAA
AGGTAAAAGCCTTAGAGTTCCTGAGAAAGTACCTTTTCGAATGACACAAAACATTGAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGT
ATTTAGGCTTTCATGTGAGCAGGTTTTACACATTATGCGGCGTGGCAGAGAGACCCTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCC
TCTGGTGGACTGGACAGCAGGAGGCGAGGCTGGGTTTGCTGGTGCTGTCTATGGTGGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAA
GAGAGAGATGGAGCGAGAGATCACCCGCAGCCTGTTTTCTTCTAGAGTAGCTGAGATTAAGGTGAACTGGTTTAAGAATAGAGATGAGAT
GCTGGTTGTGCTTCCCAAGTTGGACGGTAGCTTAGATGAATACCTAAGCTTGCAAGAGCAACTGACAGATGTGGAAAAACTGCAGGGCAA
ACTACTGGAGGAAATAGAGTTTCTAGAAGGAGCTGAAGGGGTGGATCATCCTTCTCATACTCTGCAACACAGGTATTCTGAGCACACCCA
ACTACAGACTCAGCAAAGAGCTGTTCAGGAAGCAATCCAGGTGAAGCTGAATGAATTTGAACAATGGATAACACATTATCAGGCTGCATT
CAATAATTTAGAAGCAACACAGCTTGCAAGCTTGCTTCAAGAGATAAGCACACAAATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAAC
AGCCTTTCTGCAGAATGCTGGTCAGGCCCACTTGATTAGCCAGTGCGAGCAGCTGGAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCG
CTCCGTGCTCCGTGGCTGTCTGGAGCAACTGCATCACTATGCAACCGTGGCCCTGCAGTATCCGAAGGCCATATTTCAGAAACATCGAAT
TGAACAGTGGAAGACCTGGATGGAAGAGCTCATCTGTAACACCACAGTAGAGCGTTGTCAAGAGCTCTATAGGAAATATGAAATGCAATA
TGCTCCCCAGCCACCCCCAACAGTGTGTCAGTTCATCACTGCCACTGAAATGACCCTGCAGCGATACGCAGCAGACATCAACAGCAGACT
TATTAGACAAGTGGAACGCTTGAAACAGGAAGCTGTCACTGTGCCAGTTTGTGAAGATCAGTTGAAAGAAATTGAACGTTGCATTAAAGT
TTTCCTTCATGAGAATGGAGAAGAAGGATCTTTGAGTCTAGCAAGTGTTATTATTTCTGCCCTTTGTACCCTTACAAGGCGTAACCTGAT
GATGGAAGGTGCAGCGTCAAGTGCTGGAGAACAGCTGGTTGATCTGACTTCTCGGGATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTAT
GAGCGGAAACGTCACCTGCTTGGTTCAGTTACTGAAGCAGTGCCACCTGGTGCCACAGGACTTAGATATCCCGAACCCCATGGAAGCGTC
TGAGACAGTTCACTTAGCCAATGGAGTGTATACCTCACTTCAGGAATTGAATTCGAATTTCCGGCAAATCATATTTCCAGAAGCACTTCG
ATGTTTAATGAAAGGGGAATACACGTTAGAAAGTATGCTGCATGAACTGGACGGTCTTATTGAGCAGACCACCGATGGCGTTCCCCTGCA
GACTCTAGTGGAATCTCTTCAGGCCTACTTAAGAAACGCAGCTATGGGACTGGAAGAAGAAACACATGCTCATTACATCGATGTTGCCAG
ACTACTACATGCTCAGTACGGTGAATTAATCCAACCGAGAAATGGTTCAGTTGATGAAACACCCAAAATGTCAGCTGGCCAGATGCTTTT
GGTAGCATTCGATGGCATGTTTGCTCAAGTTGAAACTGCTTTCAGCTTATTAGTTGAAAAGTTGAACAAGATGGAAATTCCCATAGCTTG
GCGAAAGATTGACATCATAAGGGAAGCCAGGAGTACTCAAGTTAATTTTTTTGATGATGATAATCACCGGCAGGTGCTAGAAGAGATTTT
CTTTCTAAAAAGACTACAGACTATTAAGGAGTTCTTCAGGCTCTGTGGTACCTTTTCTAAAACATTGTCAGGATCAAGTTCACTTGAAGA
TCAGAATACTGTGAATGGGCCTGTACAGATTGTCAATGTGAAAACCCTTTTTAGAAACTCTTGTTTCAGTGAAGACCAAATGGCCAAACC
TATCAAGGCATTCACAGCTGACTTTGTGAGGCAGCTCTTGATAGGGCTACCCAACCAAGCCCTCGGACTCACACTGTGCAGTTTTATCAG
TGCTCTGGGTGTAGACATCATTGCTCAAGTAGAGGCAAAGGACTTTGGTGCCGAAAGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGC
GGTGGAACATAACATCCAGATAGGGAAGTTCTCTCAGCTGGTTATGAACAGGGCAACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAA
GAAGCATGACTTGGTGCGAAGGCTAGAAACCAGTATTTCTTCTTGTAAGACAAGCCTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCA
GTGGCAACATGAAGATCTACTTATCAATAGACCACAAGCCATGTCAGTCACACCTCCCCCACGGTCTGCTATCCTAACCAGCATGAAAAA
GAAGCTGCATACCCTGAGCCAGATTGAAACTTCTATTGCAACAGTTCAGGAGAAGCTAGCTGCACTTGAATCAAGTATTGAACAGCGACT
CAAGTGGGCAGGTGGTGCCAACCCTGCATTGGCCCCTGTACTACAAGATTTTGAAGCAACGATAGCTGAAAGAAGAAATCTTGTCCTTAA
AGAGAGCCAAAGAGCAAGTCAGGTCACATTTCTCTGCAGCAATATCATTCATTTTGAAAGTTTACGAACAAGAACTGCAGAAGCCTTAAA
CCTGGATGCGGCGTTATTTGAACTAATCAAGCGATGTCAGCAGATGTGTTCGTTTGCATCACAGTTTAACAGTTCAGTGTCTGAGTTAGA
GCTTCGTTTATTACAGAGAGTGGACACTGGTCTTGAACATCCTATTGGCAGCTCTGAATGGCTTTTGTCAGCACACAAACAGTTGACCCA
GGATATGTCTACTCAGAGGGCAATTCAGACAGAGAAAGAGCAGCAGATAGAAACGGTCTGTGAAACAATTCAGAATCTGGTTGATAATAT
AAAGACTGTGCTCACTGGTCATAACCGACAGCTTGGAGATGTCAAACATCTCTTGAAAGCTATGGCTAAGGATGAAGAAGCTGCTCTGGC
AGATGGTGAAGATGTTCCCTATGAGAACAGTGTTAGGCAGTTTTTGGGTGAATATAAATCATGGCAAGACAACATTCAAACAGTTCTATT
TACATTAGTCCAGGCTATGGGTCAGGTTCGAAGTCAAGAACACGTTGAAATGCTCCAGGAAATCACTCCCACCTTGAAAGAACTGAAAAC
ACAAAGTCAGAGTATCTATAATAATTTAGTGAGTTTTGCATCACCCTTAGTCACCGATGCAACAAATGAATGTTCGAGTCCAACGTCATC
TGCTACTTATCAGCCATCCTTCGCTGCAGCAGTCCGGAGTAACACTGGCCAGAAGACTCAGCCTGATGTCATGTCACAGAATGCTAGAAA
GCTGATCCAAAAAAATCTTGCTACATCAGCTGATACTCCACCAAGCACCGTTCCAGGAACTGGCAAGAGTGTTGCTTGTAGTCCTAAAAA
GGCAGTCAGAGACCCTAAAACTGGGAAAGCGGTGCAAGAGAGAAACTCCTATGCAGTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTTAGA
GGGCCGAGATGTTGATCCGAATAGGAGGATGTCAGTTGCTGAACAGGTTGACTATGTCATTAAGGAAGCAACTAATCTAGATAACTTGGC
TCAGCTGTATGAAGGTTGGACAGCCTGGGTGTGAATGGCAAGACAGTAGATGAGTCTGGTTAAGCGAGGTCAGACATCCACCAGAATCAA
CTCAGCCTCAGGCATCCAAAGCCACACCACAGTCGGTGGTGATGCAACTGGGGGCTTACTCTGAGGAAACCTAGGAAATCTCGGTGCACT
AGGAAGTGAATCCCGCAGGACAGCTGCACTCAGGGATACGCCCAACACCATGGCCTGCAACCCCAGGGTCAAGGGTGAAGGAAAGCAAGC
TCACCGCCTGAACACGGAGATTGTCTTTCTGCCACAGAACAGCAGCAGACGTGTCGGGAGGTTAGCTGCGGAAAGAAATCGGGATGCCGC
GGAGCACAGAGTGATTTGGAACTCCATTCCACCTGACCCTGTGTGTACAATCCAGGAAAAAAACAAACCCCACTCAGAAACAGAGAAAAC
TGGGGTCGCGAAGAAATCACAGCCAAGGAAGATTTGATGCATTCAGATTCTCGTGTAACACTTGTTGCTTGGCAACAGTACTGGTTGGGT
TGACCAGTAAGTAGAAAAAGGCTAAAGGCTATGCGATATGAATTTCAGAAATGGACTGAAAATGGAGAGCTATGTAACAGATACACTACA
GTAGAAGAACTTACTTCTGAAATGAAGGGAAAAAAACCACCCCATCGTTCCCTACTCCTCCCCACCACTTACCCGTTCCCCCTTTACCTA
ATCTAGTAGATTAGCCATCTTTCAAATTCACTTTTATTTCAGTCCTTATATTTCATATACTTCCGTCTCGATGCTGTTAACAACTTCTGA
TAACATGGAAAATTCAAGGATTGTTTAAAGGTCTGATGATCACACACAAAATGTAATTCCGGTTATTTAAGTCATTTCTGTGATTCTATC
ATGTACAGTTTCCAGAATTGTCACTGTGCATTCAAAAGTAATGAATCTAACAGACATTTGATTTAATGTACACTCCCTTTTGCTTATAGT
GTGCATTTTTTTTGGAGGTCATTCAAATTTTCCCTCTTCTGTGATAGCTGTAGTTTCTTTCATAGAAAGTAGCTAATCCAGTGTAATCTT
TTACCTTTTTAAAAACCAAGATAGAGTATCTATTAGAGTTTTACATTGTTGATGATAGATTAACAATAAAGTGATGTTCTGGTGGAGGTA
GACTGAAATTTTTTTAATTCATGTTTTTCATTTGATACTTTTAATTTACACTTAGTAAATTAAAAGTTGTTTAATTTACTTGGCATTTTA
GGACATGTACATGAAACAGTGAAAATGAGATCCACCAACATCTTTTATTAAGTTCAGTTATTAGTCTGTGAAGTGCTTTACTTTTTGCAC
AATTTTAATAGCTTGCTATTCAGTAATACATTATAGTGAATTCATGATCAAGGTTTCCTTAAATTTAGCATTGCATTTCAGTACTGACTG
TGTAAGCTAAATTGCTGATCCAAAATAAAAACCCAGACTAGAATAGGGTTCTTAAAATCAAGTATCAATACAAAATAGAACACAATTAAA
ATCTTAATTGTTGGCTGGGCACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCATGAGGTTAGGAGAGC
GAGACCATCCTGGCTAACACGGTGAAACCCCGTCTTTACTAAAAATACAAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCC
AGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCT
GGGCAACAGAGCTAGACTCTGTGTCAAAAATAAATGACTAGATAAAAAAAAAAATTGTTTGAGTACATTTTCCCTGCATTTTAGAGATTA
GGACAGTGGTCACTTTCTAGTTGCCGTCTTCACAGACAAACTTGAAAGGTATTAAGGAAAAAATTCCACATAGCTCTGGGCCTTTTTTGT
ATTCTGATTGCCACGTTAATCTGTAATCGTTAAGTACCCATGAAAGAATGTGTTTCAGTATCAGTGCTTTTTTGGTACTTTAACAAGTAT
TGTAGGCACGGTGGATTTTTTTGAAATACCCATGTGTCCAATAGCAAGTTAAGGAACCTAGCGCATCAAATTTTGTTTTCTTCATTCATT
TGGAACCTTATTTTCGCAAAAAACCTAGCTGGAATAATAATGCCATATTGTATTTTGCACACTGCTTTATTTTCTAGAGGCTCTGGGAGC
AAATTACATTCATCACATTACCTCTGCTCTCTCAAGATTAAAGTCTTTCAGCAACATTCTTTATTGTCATCATAAGGAAAAACTTTTATC
GCAATGATAGTCAGTTCACATTAGTTTAGCACTATAGATAGTATTCAGAAATTGCTTTCTCTTTGGTAAAGAAGATAAATAGGTGAATTT
TATTGCCTGTGTTTTCAGGCTTCAGAGGTACCTGGCACCTTACTCAAGCAAAAACAAAAAACAGCTTTACTTCAAAAGCATGTGCCTCTG
GTAAATTATCCATCACTTTTGTTTTAAAGTGGTCCCTCCAAGAATAATGTGGCATACACAGTGGGTTTGGTTGTAAGGCAGATGTAATAG
ATGACTTCAAAAGCCTGCTCCTTACTGCACTCTGGACAAGGCCCTGGTCTGTATAGTTTGGCTTCCTCTGTTAAGTCATTCTACAAGGTG
ACTTGCCATTTGAACTTTCGTAAGAGACCTCAGCAGTTAGACTGAGAAAAGTTAGAGTGCTGTAGTTATGAAGTCATACATTTTTGATAA
AATACCTGTGGAAAACCAGGGATCCTCTCCTGTTTCTCTCTCTTGCCTCCCCCTTTCCCTCCATTCCTCTGTCGCCTCCCCCTCTCCTCC
ACTTTCTTTAAGAATCAGGGGGTACAGAATAACCTACAAACAACCTCTTCAAAGTACCCTTGGAAATTGAAGTTCAATCTTAAGTTTTTT
GCTGTCTTTAATTTACTAGAATTGCCTAATTTTTAGTTGATTTCTCTACAGAGCTTAGCTTGTGTAGTTATTTCTCTTTTACTGTTGCTT
TGGTGTGTCTTGAAGTTTGATTGATTATTTTTGGTCATTGAGTTCTTAGTGTAGTTTGCTAGATGATTATTAAGATTCTTTTGTGTCTGA
CACTTGTGGTGAGTTGCTTTTGAAATCTGTTGAGATTTCCATGTGAGAACTGATAATCAGGCTCTTGATCTGCTTCCCTAAATTACTTTT
TTAGAGCCCAAACCCCAGGTTTAGGGTGAGGGTTTGTAATACAAAGAAACACTTCCATCACTTCTGCCCTTAACCCTTGCCTCTATTACC
TAAGCTTAGTAAGTAGTTTTCTTAATATTGTCCAATGTTTGGTGTTATCTGCATTGTTTTTTGTTTTTTTAATTGTGGTTGTTCTGACGT
GTGAAATTTAAGGAAAGAGCCATTTTTTAAAAATGCCGAGCAGGGCAATGCAAGTACAGCCAAATATTAGACTTGATGTGCAATCTTCGG
TCCTTTTTAATCTGGGGTATTATAGGCAGTACTTTAAATTGCAAAGTCTTCCGGGCCTATTTTCCTCTACATTTTTGTAATTAACTCTGG
GGGCTTACTTGTTTTGGCAGTACTGAAATCAAAGGAGCTGGTTCTTCTTTTCTCCCAATTATTTTCATATGAAAGCACCTACAATTAGCC
TGTTAGTCCTATTCAGATACATCAAATATCAGTGAATGCTTTACTATTCGCACATTTAAGCATCTTTGTTTTACATAAAATTAGAGTATG
AAAACCAGTGTTCAATTTTTTATCTTGTTGAGCTTGTAAAATGCCAGCAATTTAAAACTAGGACTTTTCCCCCCATAAGCCAAGGAGGTA
GAATTACTAATACAAGGGTTAAAGAAGGTAGATTTTGTTTTCAATATTTGGGTAATATTAGAAAGATTCTTCCCACAGGGAAGAACTAGC
AAGTGTCCCAATTTTTTCCAAACGTTGGGGAGGGGAAAATTCACTGTATCATGAAACCCTAAGGGTTTGTTGCACTTCCTGCTTTTTAGG
CCTGGATAACAGTATCACCATCCTTATTTACAGAAGGGTAAAACTGACTCTTAATGAGAAAAGCTTTATAAGTTCAAGGGCTGTAAAATA
TGAACTACTTAGGGTCGTTTGCCTTCCATGGGAACTTGGCTAGACTTAGAAAAAGCTGTTTGTTGTGCTAATGTAAAAGTGTCATACAAT
TTAGAAGATTTTTGAAGATGGTAAACTTAGAAGAATTCTATGTTCTGAAATGCACACTTTTAGAATGTTTTTCTTTGAAAACAGGCTAAT
AGTTTTTTCTTTTTTTGACAAAGTTTCAGCTCCTCTTTAAAGTTATTGTGTCATTTTTCTGGTTTAAATTTCCCTTATATTTCCACCTGT
AATGTCAGTGGCAACAACATCATACTTCACTTACTTGTTAATTTACTTTTTACCCTTATTCTAAGAGCAAGTTGAGTTGAACTGAATCTT
CCTTGTCTTAGTAACAATGTATAAATAGTGGCTTTTCTGTACAAAAGGTTGTAATGCCTCCTGATGGATATAATTTTGTGATTGTATTTA
AAAGTTGAATAAATCACACCAGCTTCCTGAAAATGTTCATAATGCATCTTTTGGAAAACAAATACATGCCTACTTTGTGCATATTTGCAT

>5042_5042_4_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000396024_SMG1_chr16_18883946_ENST00000446231_length(amino acids)=3234AA_BP=203
MLCASFKMSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKEL
ASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVA
LAKGRRAEDGSVIDYELIDQDARMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVIS
TVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALS
SSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRT
GKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTA
DNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTE
MKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVL
TLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSF
ESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQT
SRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKEQTVPI
RSHLMELGLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSSC
AISFCKSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIESESTVHIGVGEP
DFILGQLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDED
ITLQITESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRV
EQSTDDMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISL
SSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRR
VTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDA
IENALEKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKP
KKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAA
LQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSY
ARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGR
ETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLS
LQEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEATQLASLLQEIS
TQMDLGPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWKTWMEELICNTTV
ERCQELYRKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHENGEEGSLSLASV
IISALCTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVHLANGVYTSLQEL
NSNFRQIIFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQYGELIQPRNGS
VDETPKMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKRLQTIKEFFRLCG
TFSKTLSGSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVDIIAQVEAKDFG
AESKVSVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQWQHEDLLINRPQAMSV
TPPPRSAILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRASQVTFLCSNII
HFESLRTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMSTQRAIQTEKEQQI
ETVCETIQNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQAMGQVRSQEHVE
MLQEITPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQKNLATSADTPPST

--------------------------------------------------------------
>5042_5042_5_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000421017_SMG1_chr16_18883946_ENST00000389467_length(transcript)=14539nt_BP=724nt
GCTCAGCATTTGGGGACGCTCTCAGCTCTCGGCGCACGGCCCAGGTTATCTTGTAGCATAGCAACTTCGGATTTCACTCTACCCGGAGAG
TTTCCCGCTTGGTTGAACACATTGGCCTCAGGAAGCTTCCTTCAAAATGTCTACTGTTCACGAAATCCTGTGCAAGCTCAGCTTGGAGGG
TGATCACTCTACACCCCCAAGTGCATATGGGTCTGTCAAAGCCTATACTAACTTTGATGCTGAGCGGGATGCTTTGAACATTGAAACAGC
CATCAAGACCAAAGGTGTGGATGAGGTCACCATTGTCAACATTTTGACCAACCGCAGCAATGCACAGAGACAGGATATTGCCTTCGCCTA
CCAGAGAAGGACCAAAAAGGAACTTGCATCAGCACTGAAGTCAGCCTTATCTGGCCACCTGGAGACGGTGATTTTGGGCCTATTGAAGAC
ACCTGCTCAGTATGACGCTTCTGAGCTAAAAGCTTCCATGAAGGGGCTGGGAACCGACGAGGACTCTCTCATTGAGATCATCTGCTCCAG
AACCAACCAGGAGCTGCAGGAAATTAACAGAGTCTACAAGGAAATGTACAAGACTGATCTGGAGAAGGACATTATTTCGGACACATCTGG
TGACTTCCGCAAGCTGATGGTTGCCCTGGCAAAGGGTAGAAGAGCAGAGGATGGCTCTGTCATTGATTATGAACTGATTGACCAAGATGC
TCGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGC
CATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTC
TTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAA
GAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGC
ACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGC
ATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAG
TGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCA
AGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTAT
TTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTC
AACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCT
GAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCA
GGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAA
TCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAA
TCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAG
ACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGC
ATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTC
AGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCAT
CTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAA
AACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGA
TTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAA
CTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCT
ACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCAT
TGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAA
TGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCT
AAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAG
TGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAA
AATTAAAGAACAAACAGTCCCAATTAGAAGCCATCTCATGGAATTAGGTCTAACAGCAGCAAAATTTGCTAGAAAACGAGGGAATGTGTC
CCTTGCAACAAGACTGCTGGCACAGTGCAGTGAAGTTCAGCTGGGAAAGACCACCACTGCACAGGATTTAGTCCAACATTTTAAAAAACT
ATCAACCCAAGGTCAAGTGGATGAAAAATGGGGGCCCGAACTTGATATTGAAAAAACCAAATTGCTTTATACAGCAGGCCAGTCAACACA
TGCAATGGAAATGTTGAGTTCTTGTGCCATATCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGTTGCTAAATCAATTCTGACACTGGC
TAAATGGATCCAGGCAGAATGGAAAGAGATTTCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCACCAACAGAACTTCACAGGTCTTTC
TACTTTGTCTAAAAACATACTCACTCTAATAGAACTGCCATCTGTTAATACGATGGAAGAAGAGTATCCTCGGATCGAGAGTGAATCTAC
AGTGCATATTGGAGTTGGAGAACCTGACTTCATTTTGGGACAGTTGTATCACCTGTCTTCAGTACAGGCACCTGAAGTAGCCAAATCTTG
GGCAGCGTTGGCCAGCTGGGCTTATAGGTGGGGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGAAGGTGTTCGTCTGCTGCCTAGAGA
AAAATCTGAAGTTCAGAATCTACTTCCAGACACTATAACTGAGGAAGAGAAAGAGAGAATATATGGTATTCTTGGACAGGCTGTGTGTCG
GCCGGCGGGGATTCAGGATGAAGATATAACACTTCAGATAACTGAGAGTGAAGACAACGAAGAAGATGACATGGTTGATGTTATCTGGCG
TCAGTTGATATCAAGCTGCCCATGGCTTTCAGAACTTGATGAAAGTGCAACTGAAGGAGTTATTAAAGTGTGGAGGAAAGTTGTAGATAG
AATATTCAGCCTGTACAAACTCTCTTGCAGTGCATACTTTACTTTCCTTAAACTCAACGCTGGTCAAATTCCTTTAGATGAGGATGACCC
TAGGCTGCATTTAAGTCACAGAGTGGAACAGAGCACTGATGACATGATTGTGATGGCCACATTGCGCCTGCTGCGGTTGCTCGTGAAGCA
TGCTGGTGAGCTTCGGCAGTATCTGGAGCACGGCTTGGAGACAACACCCACTGCACCATGGAGAGGAATTATTCCGCAACTTTTCTCACG
CTTAAACCACCCTGAAGTGTATGTGCGCCAAAGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGATTCCCCACATCTCATATTGTATCC
TGCAATAGTGGGTACCATATCGCTTAGTAGTGAATCCCAGGCTTCAGGAAATAAATTTTCCACTGCAATTCCAACTTTACTTGGCAATAT
TCAAGGAGAAGAATTGCTGGTTTCTGAATGTGAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAATAAGGATGAACCTAAAAGTGGATT
AAATGAAGACCAAGCCATGATGCAGGATTGTTACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAACCCCACCATGGTATTACAGGTTCA
GATGCTCGTGGCTGAACTGCGCAGGGTCACTGTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCTGCAACAACACATGTATGTCCTGAG
ACGAATTCAGCAGCTTGAAGATGAGGTGAAGAGAGTCCAGAACAACAACACCTTACGCAAAGAAGAGAAAATTGCAATCATGAGGGAGAA
GCACACAGCTTTGATGAAGCCCATCGTATTTGCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCCTGCAGAAACACCTCATGAAAAATG
GTTTCAGGATAACTATGGTGATGCCATTGAAAATGCCCTAGAAAAACTGAAGACTCCATTGAACCCTGCAAAGCCTGGGAGCAGCTGGAT
TCCATTTAAAGAGATAATGCTAAGTTTGCAACAGAGAGCACAGAAACGTGCAAGTTACATCTTGCGTCTTGAAGAAATCAGTCCATGGTT
GGCTGCCATGACTAACACTGAAATTGCTCTTCCTGGGGAAGTCTCAGCCAGAGACACTGTCACAATCCATAGTGTGGGCGGAACCATCAC
AATCTTACCGACTAAAACCAAGCCAAAGAAACTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCCTTATCTTTTCAAAGGACTGGAGGA
TTTACATCTGGATGAGAGAATAATGCAGTTCCTATCTATTGTGAATACCATGTTTGCTACAATTAATCGCCAAGAAACACCCCGGTTCCA
TGCTCGACACTATTCTGTAACACCACTAGGAACAAGATCAGGACTAATCCAGTGGGTAGATGGAGCCACACCCTTATTTGGTCTTTACAA
ACGATGGCAACAACGGGAAGCTGCCTTACAAGCACAAAAGGCCCAAGATTCCTACCAAACTCCTCAGAATCCTGGAATTGTACCCCGTCC
TAGTGAACTTTATTACAGTAAAATTGGCCCTGCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTCCCGTCGGGATTGGCCTCTTCATGT
AATGAAGGCAGTATTGGAAGAGTTAATGGAGGCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTGGTCATCTTGCACAACACCTGATGA
ATGGTGGAGAGTTACGCAGTCTTATGCAAGATCTACTGCAGTCATGTCTATGGTTGGATACATAATTGGCCTTGGAGACAGACATCTGGA
TAATGTTCTTATAGATATGACGACTGGAGAAGTTGTTCACATAGATTACAATGTTTGCTTTGAAAAAGGTAAAAGCCTTAGAGTTCCTGA
GAAAGTACCTTTTCGAATGACACAAAACATTGAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGTATTTAGGCTTTCATGTGAGCAGGT
TTTACACATTATGCGGCGTGGCAGAGAGACCCTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCCTCTGGTGGACTGGACAGCAGGAGG
CGAGGCTGGGTTTGCTGGTGCTGTCTATGGTGGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAAGAGAGAGATGGAGCGAGAGATCAC
CCGCAGCCTGTTTTCTTCTAGAGTAGCTGAGATTAAGGTGAACTGGTTTAAGAATAGAGATGAGATGCTGGTTGTGCTTCCCAAGTTGGA
CGGTAGCTTAGATGAATACCTAAGCTTGCAAGAGCAACTGACAGATGTGGAAAAACTGCAGGGCAAACTACTGGAGGAAATAGAGTTTCT
AGAAGGAGCTGAAGGGGTGGATCATCCTTCTCATACTCTGCAACACAGGTATTCTGAGCACACCCAACTACAGACTCAGCAAAGAGCTGT
TCAGGAAGCAATCCAGGTGAAGCTGAATGAATTTGAACAATGGATAACACATTATCAGGCTGCATTCAATAATTTAGAAGCAACACAGCT
TGCAAGCTTGCTTCAAGAGATAAGCACACAAATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAACAGCCTTTCTGCAGAATGCTGGTCA
GGCCCACTTGATTAGCCAGTGCGAGCAGCTGGAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCGCTCCGTGCTCCGTGGCTGTCTGGA
GCAACTGCATCACTATGCAACCGTGGCCCTGCAGTATCCGAAGGCCATATTTCAGAAACATCGAATTGAACAGTGGAAGACCTGGATGGA
AGAGCTCATCTGTAACACCACAGTAGAGCGTTGTCAAGAGCTCTATAGGAAATATGAAATGCAATATGCTCCCCAGCCACCCCCAACAGT
GTGTCAGTTCATCACTGCCACTGAAATGACCCTGCAGCGATACGCAGCAGACATCAACAGCAGACTTATTAGACAAGTGGAACGCTTGAA
ACAGGAAGCTGTCACTGTGCCAGTTTGTGAAGATCAGTTGAAAGAAATTGAACGTTGCATTAAAGTTTTCCTTCATGAGAATGGAGAAGA
AGGATCTTTGAGTCTAGCAAGTGTTATTATTTCTGCCCTTTGTACCCTTACAAGGCGTAACCTGATGATGGAAGGTGCAGCGTCAAGTGC
TGGAGAACAGCTGGTTGATCTGACTTCTCGGGATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTATGAGCGGAAACGTCACCTGCTTGGT
TCAGTTACTGAAGCAGTGCCACCTGGTGCCACAGGACTTAGATATCCCGAACCCCATGGAAGCGTCTGAGACAGTTCACTTAGCCAATGG
AGTGTATACCTCACTTCAGGAATTGAATTCGAATTTCCGGCAAATCATATTTCCAGAAGCACTTCGATGTTTAATGAAAGGGGAATACAC
GTTAGAAAGTATGCTGCATGAACTGGACGGTCTTATTGAGCAGACCACCGATGGCGTTCCCCTGCAGACTCTAGTGGAATCTCTTCAGGC
CTACTTAAGAAACGCAGCTATGGGACTGGAAGAAGAAACACATGCTCATTACATCGATGTTGCCAGACTACTACATGCTCAGTACGGTGA
ATTAATCCAACCGAGAAATGGTTCAGTTGATGAAACACCCAAAATGTCAGCTGGCCAGATGCTTTTGGTAGCATTCGATGGCATGTTTGC
TCAAGTTGAAACTGCTTTCAGCTTATTAGTTGAAAAGTTGAACAAGATGGAAATTCCCATAGCTTGGCGAAAGATTGACATCATAAGGGA
AGCCAGGAGTACTCAAGTTAATTTTTTTGATGATGATAATCACCGGCAGGTGCTAGAAGAGATTTTCTTTCTAAAAAGACTACAGACTAT
TAAGGAGTTCTTCAGGCTCTGTGGTACCTTTTCTAAAACATTGTCAGGATCAAGTTCACTTGAAGATCAGAATACTGTGAATGGGCCTGT
ACAGATTGTCAATGTGAAAACCCTTTTTAGAAACTCTTGTTTCAGTGAAGACCAAATGGCCAAACCTATCAAGGCATTCACAGCTGACTT
TGTGAGGCAGCTCTTGATAGGGCTACCCAACCAAGCCCTCGGACTCACACTGTGCAGTTTTATCAGTGCTCTGGGTGTAGACATCATTGC
TCAAGTAGAGGCAAAGGACTTTGGTGCCGAAAGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGCGGTGGAACATAACATCCAGATAGG
GAAGTTCTCTCAGCTGGTTATGAACAGGGCAACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAAGAAGCATGACTTGGTGCGAAGGCT
AGAAACCAGTATTTCTTCTTGTAAGACAAGCCTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCAGCAGTGGCAACATGAAGATCTACT
TATCAATAGACCACAAGCCATGTCAGTCACACCTCCCCCACGGTCTGCTATCCTAACCAGCATGAAAAAGAAGCTGCATACCCTGAGCCA
GATTGAAACTTCTATTGCAACAGTTCAGGAGAAGCTAGCTGCACTTGAATCAAGTATTGAACAGCGACTCAAGTGGGCAGGTGGTGCCAA
CCCTGCATTGGCCCCTGTACTACAAGATTTTGAAGCAACGATAGCTGAAAGAAGAAATCTTGTCCTTAAAGAGAGCCAAAGAGCAAGTCA
GGTCACATTTCTCTGCAGCAATATCATTCATTTTGAAAGTTTACGAACAAGAACTGCAGAAGCCTTAAACCTGGATGCGGCGTTATTTGA
ACTAATCAAGCGATGTCAGCAGATGTGTTCGTTTGCATCACAGTTTAACAGTTCAGTGTCTGAGTTAGAGCTTCGTTTATTACAGAGAGT
GGACACTGGTCTTGAACATCCTATTGGCAGCTCTGAATGGCTTTTGTCAGCACACAAACAGTTGACCCAGGATATGTCTACTCAGAGGGC
AATTCAGACAGAGAAAGAGCAGCAGATAGAAACGGTCTGTGAAACAATTCAGAATCTGGTTGATAATATAAAGACTGTGCTCACTGGTCA
TAACCGACAGCTTGGAGATGTCAAACATCTCTTGAAAGCTATGGCTAAGGATGAAGAAGCTGCTCTGGCAGATGGTGAAGATGTTCCCTA
TGAGAACAGTGTTAGGCAGTTTTTGGGTGAATATAAATCATGGCAAGACAACATTCAAACAGTTCTATTTACATTAGTCCAGGCTATGGG
TCAGGTTCGAAGTCAAGAACACGTTGAAATGCTCCAGGAAATCACTCCCACCTTGAAAGAACTGAAAACACAAAGTCAGAGTATCTATAA
TAATTTAGTGAGTTTTGCATCACCCTTAGTCACCGATGCAACAAATGAATGTTCGAGTCCAACGTCATCTGCTACTTATCAGCCATCCTT
CGCTGCAGCAGTCCGGAGTAACACTGGCCAGAAGACTCAGCCTGATGTCATGTCACAGAATGCTAGAAAGCTGATCCAAAAAAATCTTGC
TACATCAGCTGATACTCCACCAAGCACCGTTCCAGGAACTGGCAAGAGTGTTGCTTGTAGTCCTAAAAAGGCAGTCAGAGACCCTAAAAC
TGGGAAAGCGGTGCAAGAGAGAAACTCCTATGCAGTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTTAGAGGGCCGAGATGTTGATCCGAA
TAGGAGGATGTCAGTTGCTGAACAGGTTGACTATGTCATTAAGGAAGCAACTAATCTAGATAACTTGGCTCAGCTGTATGAAGGTTGGAC
AGCCTGGGTGTGAATGGCAAGACAGTAGATGAGTCTGGTTAAGCGAGGTCAGACATCCACCAGAATCAACTCAGCCTCAGGCATCCAAAG
CCACACCACAGTCGGTGGTGATGCAACTGGGGGCTTACTCTGAGGAAACCTAGGAAATCTCGGTGCACTAGGAAGTGAATCCCGCAGGAC
AGCTGCACTCAGGGATACGCCCAACACCATGGCCTGCAACCCCAGGGTCAAGGGTGAAGGAAAGCAAGCTCACCGCCTGAACACGGAGAT
TGTCTTTCTGCCACAGAACAGCAGCAGACGTGTCGGGAGGTTAGCTGCGGAAAGAAATCGGGATGCCGCGGAGCACAGAGTGATTTGGAA
CTCCATTCCACCTGACCCTGTGTGTACAATCCAGGAAAAAAACAAACCCCACTCAGAAACAGAGAAAACTGGGGTCGCGAAGAAATCACA
GCCAAGGAAGATTTGATGCATTCAGATTCTCGTGTAACACTTGTTGCTTGGCAACAGTACTGGTTGGGTTGACCAGTAAGTAGAAAAAGG
CTAAAGGCTATGCGATATGAATTTCAGAAATGGACTGAAAATGGAGAGCTATGTAACAGATACACTACAGTAGAAGAACTTACTTCTGAA
ATGAAGGGAAAAAAACCACCCCATCGTTCCCTACTCCTCCCCACCACTTACCCGTTCCCCCTTTACCTAATCTAGTAGATTAGCCATCTT
TCAAATTCACTTTTATTTCAGTCCTTATATTTCATATACTTCCGTCTCGATGCTGTTAACAACTTCTGATAACATGGAAAATTCAAGGAT
TGTTTAAAGGTCTGATGATCACACACAAAATGTAATTCCGGTTATTTAAGTCATTTCTGTGATTCTATCATGTACAGTTTCCAGAATTGT
CACTGTGCATTCAAAAGTAATGAATCTAACAGACATTTGATTTAATGTACACTCCCTTTTGCTTATAGTGTGCATTTTTTTTGGAGGTCA
TTCAAATTTTCCCTCTTCTGTGATAGCTGTAGTTTCTTTCATAGAAAGTAGCTAATCCAGTGTAATCTTTTACCTTTTTAAAAACCAAGA
TAGAGTATCTATTAGAGTTTTACATTGTTGATGATAGATTAACAATAAAGTGATGTTCTGGTGGAGGTAGACTGAAATTTTTTTAATTCA
TGTTTTTCATTTGATACTTTTAATTTACACTTAGTAAATTAAAAGTTGTTTAATTTACTTGGCATTTTAGGACATGTACATGAAACAGTG
AAAATGAGATCCACCAACATCTTTTATTAAGTTCAGTTATTAGTCTGTGAAGTGCTTTACTTTTTGCACAATTTTAATAGCTTGCTATTC
AGTAATACATTATAGTGAATTCATGATCAAGGTTTCCTTAAATTTAGCATTGCATTTCAGTACTGACTGTGTAAGCTAAATTGCTGATCC
AAAATAAAAACCCAGACTAGAATAGGGTTCTTAAAATCAAGTATCAATACAAAATAGAACACAATTAAAATCTTAATTGTTGGCTGGGCA
CAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCATGAGGTTAGGAGAGCGAGACCATCCTGGCTAACACG
GTGAAACCCCGTCTTTACTAAAAATACAAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGC
AGGAGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGCTAGACTCTG
TGTCAAAAATAAATGACTAGATAAAAAAAAAAATTGTTTGAGTACATTTTCCCTGCATTTTAGAGATTAGGACAGTGGTCACTTTCTAGT
TGCCGTCTTCACAGACAAACTTGAAAGGTATTAAGGAAAAAATTCCACATAGCTCTGGGCCTTTTTTGTATTCTGATTGCCACGTTAATC
TGTAATCGTTAAGTACCCATGAAAGAATGTGTTTCAGTATCAGTGCTTTTTTGGTACTTTAACAAGTATTGTAGGCACGGTGGATTTTTT
TGAAATACCCATGTGTCCAATAGCAAGTTAAGGAACCTAGCGCATCAAATTTTGTTTTCTTCATTCATTTGGAACCTTATTTTCGCAAAA
AACCTAGCTGGAATAATAATGCCATATTGTATTTTGCACACTGCTTTATTTTCTAGAGGCTCTGGGAGCAAATTACATTCATCACATTAC
CTCTGCTCTCTCAAGATTAAAGTCTTTCAGCAACATTCTTTATTGTCATCATAAGGAAAAACTTTTATCGCAATGATAGTCAGTTCACAT
TAGTTTAGCACTATAGATAGTATTCAGAAATTGCTTTCTCTTTGGTAAAGAAGATAAATAGGTGAATTTTATTGCCTGTGTTTTCAGGCT
TCAGAGGTACCTGGCACCTTACTCAAGCAAAAACAAAAAACAGCTTTACTTCAAAAGCATGTGCCTCTGGTAAATTATCCATCACTTTTG
TTTTAAAGTGGTCCCTCCAAGAATAATGTGGCATACACAGTGGGTTTGGTTGTAAGGCAGATGTAATAGATGACTTCAAAAGCCTGCTCC
TTACTGCACTCTGGACAAGGCCCTGGTCTGTATAGTTTGGCTTCCTCTGTTAAGTCATTCTACAAGGTGACTTGCCATTTGAACTTTCGT
AAGAGACCTCAGCAGTTAGACTGAGAAAAGTTAGAGTGCTGTAGTTATGAAGTCATACATTTTTGATAAAATACCTGTGGAAAACCAGGG
ATCCTCTCCTGTTTCTCTCTCTTGCCTCCCCCTTTCCCTCCATTCCTCTGTCGCCTCCCCCTCTCCTCCACTTTCTTTAAGAATCAGGGG
GTACAGAATAACCTACAAACAACCTCTTCAAAGTACCCTTGGAAATTGAAGTTCAATCTTAAGTTTTTTGCTGTCTTTAATTTACTAGAA
TTGCCTAATTTTTAGTTGATTTCTCTACAGAGCTTAGCTTGTGTAGTTATTTCTCTTTTACTGTTGCTTTGGTGTGTCTTGAAGTTTGAT
TGATTATTTTTGGTCATTGAGTTCTTAGTGTAGTTTGCTAGATGATTATTAAGATTCTTTTGTGTCTGACACTTGTGGTGAGTTGCTTTT
GAAATCTGTTGAGATTTCCATGTGAGAACTGATAATCAGGCTCTTGATCTGCTTCCCTAAATTACTTTTTTAGAGCCCAAACCCCAGGTT
TAGGGTGAGGGTTTGTAATACAAAGAAACACTTCCATCACTTCTGCCCTTAACCCTTGCCTCTATTACCTAAGCTTAGTAAGTAGTTTTC
TTAATATTGTCCAATGTTTGGTGTTATCTGCATTGTTTTTTGTTTTTTTAATTGTGGTTGTTCTGACGTGTGAAATTTAAGGAAAGAGCC
ATTTTTTAAAAATGCCGAGCAGGGCAATGCAAGTACAGCCAAATATTAGACTTGATGTGCAATCTTCGGTCCTTTTTAATCTGGGGTATT
ATAGGCAGTACTTTAAATTGCAAAGTCTTCCGGGCCTATTTTCCTCTACATTTTTGTAATTAACTCTGGGGGCTTACTTGTTTTGGCAGT
ACTGAAATCAAAGGAGCTGGTTCTTCTTTTCTCCCAATTATTTTCATATGAAAGCACCTACAATTAGCCTGTTAGTCCTATTCAGATACA
TCAAATATCAGTGAATGCTTTACTATTCGCACATTTAAGCATCTTTGTTTTACATAAAATTAGAGTATGAAAACCAGTGTTCAATTTTTT
ATCTTGTTGAGCTTGTAAAATGCCAGCAATTTAAAACTAGGACTTTTCCCCCCATAAGCCAAGGAGGTAGAATTACTAATACAAGGGTTA
AAGAAGGTAGATTTTGTTTTCAATATTTGGGTAATATTAGAAAGATTCTTCCCACAGGGAAGAACTAGCAAGTGTCCCAATTTTTTCCAA
ACGTTGGGGAGGGGAAAATTCACTGTATCATGAAACCCTAAGGGTTTGTTGCACTTCCTGCTTTTTAGGCCTGGATAACAGTATCACCAT
CCTTATTTACAGAAGGGTAAAACTGACTCTTAATGAGAAAAGCTTTATAAGTTCAAGGGCTGTAAAATATGAACTACTTAGGGTCGTTTG
CCTTCCATGGGAACTTGGCTAGACTTAGAAAAAGCTGTTTGTTGTGCTAATGTAAAAGTGTCATACAATTTAGAAGATTTTTGAAGATGG
TAAACTTAGAAGAATTCTATGTTCTGAAATGCACACTTTTAGAATGTTTTTCTTTGAAAACAGGCTAATAGTTTTTTCTTTTTTTGACAA
AGTTTCAGCTCCTCTTTAAAGTTATTGTGTCATTTTTCTGGTTTAAATTTCCCTTATATTTCCACCTGTAATGTCAGTGGCAACAACATC
ATACTTCACTTACTTGTTAATTTACTTTTTACCCTTATTCTAAGAGCAAGTTGAGTTGAACTGAATCTTCCTTGTCTTAGTAACAATGTA
TAAATAGTGGCTTTTCTGTACAAAAGGTTGTAATGCCTCCTGATGGATATAATTTTGTGATTGTATTTAAAAGTTGAATAAATCACACCA
GCTTCCTGAAAATGTTCATAATGCATCTTTTGGAAAACAAATACATGCCTACTTTGTGCATATTTGCATTAACATGGCAAAGATTGTATG

>5042_5042_5_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000421017_SMG1_chr16_18883946_ENST00000389467_length(amino acids)=3228AA_BP=196
MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSA
LSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRA
EDGSVIDYELIDQDARMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATK
KHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDL
LQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLE
RLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHG
NNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLS
QGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGR
NSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVE
CTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGP
LRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKEQTVPIRSHLMEL
GLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSSCAISFCKS
VKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIESESTVHIGVGEPDFILGQL
YHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDEDITLQITE
SEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTDDM
IVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISLSSESQAS
GNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDE
LWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIENALEK
LKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLFLG
SDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAQ
DSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVM
SMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLL
EAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLSLQEQLTD
VEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEATQLASLLQEISTQMDLGP
PSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWKTWMEELICNTTVERCQELY
RKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHENGEEGSLSLASVIISALCT
LTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVHLANGVYTSLQELNSNFRQI
IFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQYGELIQPRNGSVDETPKM
SAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKRLQTIKEFFRLCGTFSKTLS
GSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVDIIAQVEAKDFGAESKVSV
DDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQQWQHEDLLINRPQAMSVTPPPRS
AILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRASQVTFLCSNIIHFESLR
TRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMSTQRAIQTEKEQQIETVCET
IQNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQAMGQVRSQEHVEMLQEIT
PTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQKNLATSADTPPSTVPGTGK

--------------------------------------------------------------
>5042_5042_6_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000421017_SMG1_chr16_18883946_ENST00000446231_length(transcript)=14536nt_BP=724nt
GCTCAGCATTTGGGGACGCTCTCAGCTCTCGGCGCACGGCCCAGGTTATCTTGTAGCATAGCAACTTCGGATTTCACTCTACCCGGAGAG
TTTCCCGCTTGGTTGAACACATTGGCCTCAGGAAGCTTCCTTCAAAATGTCTACTGTTCACGAAATCCTGTGCAAGCTCAGCTTGGAGGG
TGATCACTCTACACCCCCAAGTGCATATGGGTCTGTCAAAGCCTATACTAACTTTGATGCTGAGCGGGATGCTTTGAACATTGAAACAGC
CATCAAGACCAAAGGTGTGGATGAGGTCACCATTGTCAACATTTTGACCAACCGCAGCAATGCACAGAGACAGGATATTGCCTTCGCCTA
CCAGAGAAGGACCAAAAAGGAACTTGCATCAGCACTGAAGTCAGCCTTATCTGGCCACCTGGAGACGGTGATTTTGGGCCTATTGAAGAC
ACCTGCTCAGTATGACGCTTCTGAGCTAAAAGCTTCCATGAAGGGGCTGGGAACCGACGAGGACTCTCTCATTGAGATCATCTGCTCCAG
AACCAACCAGGAGCTGCAGGAAATTAACAGAGTCTACAAGGAAATGTACAAGACTGATCTGGAGAAGGACATTATTTCGGACACATCTGG
TGACTTCCGCAAGCTGATGGTTGCCCTGGCAAAGGGTAGAAGAGCAGAGGATGGCTCTGTCATTGATTATGAACTGATTGACCAAGATGC
TCGGATGTGGGCGCTATCTCCAACTGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGC
CATTCAGTATGCTGTGCTCTACACATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTC
TTTGTTTGATGGAGCTGTGATTAGCACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAA
GAAAGATAACCTTAACCAGGACACGAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGC
ACCTTTATTCTCTCTTCCGTCTTTCCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGC
ATGCAGCAGTCTACATGCTCTGTCCTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAG
TGGAACTCGTATTCGACAAGCATTTGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCA
AGAAATTTCTTTAGCATTAAGAAGTCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTAT
TTTGTATGGGAACTCTCATAGAACAGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTC
AACAATTCCACGCAATCTCCTGAAGACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCT
GAGAACCCCACTGGGCAGAGCTCAAGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCA
GGATGTTAGTCAGTGGACAACTGCAGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAA
TCTGGAGAAATTAATGTATAATGCATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAA
TCGCCAAACTTGTCAGGACTGGCTAACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAG
ACATGGCTTTGACTTGCTTACAGAGATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGC
ATTATGTGAACTTCATTGTCCTGAAGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTC
AGTGGCTCAACAGGCTGAAGGGAGGTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCAT
CTCCAGCTTTGACAAATCGGTGCTCACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAA
AACTGTGCTGTCCAAACCGACTGACTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGA
TTGGGCTGCTGTGCAGGAATGGCAGAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAA
CTATATAAAATCATTAAGCAGCTTTGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCT
ACTTGCTGGAGGATCAAAAGAAAAAATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCAT
TGAAGTTCAATTGTTAAGAAGTTCTGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAA
TGTGGTAAAGTACTTGAAGCAAACATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCT
AAGTACCTTGCAGCTGTATTGCTCATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAG
TGAAGCTTTACGTTCATGTAAACAGCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAA
AATTAAAGAACAAACAGTCCCAATTAGAAGCCATCTCATGGAATTAGGTCTAACAGCAGCAAAATTTGCTAGAAAACGAGGGAATGTGTC
CCTTGCAACAAGACTGCTGGCACAGTGCAGTGAAGTTCAGCTGGGAAAGACCACCACTGCACAGGATTTAGTCCAACATTTTAAAAAACT
ATCAACCCAAGGTCAAGTGGATGAAAAATGGGGGCCCGAACTTGATATTGAAAAAACCAAATTGCTTTATACAGCAGGCCAGTCAACACA
TGCAATGGAAATGTTGAGTTCTTGTGCCATATCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGTTGCTAAATCAATTCTGACACTGGC
TAAATGGATCCAGGCAGAATGGAAAGAGATTTCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCACCAACAGAACTTCACAGGTCTTTC
TACTTTGTCTAAAAACATACTCACTCTAATAGAACTGCCATCTGTTAATACGATGGAAGAAGAGTATCCTCGGATCGAGAGTGAATCTAC
AGTGCATATTGGAGTTGGAGAACCTGACTTCATTTTGGGACAGTTGTATCACCTGTCTTCAGTACAGGCACCTGAAGTAGCCAAATCTTG
GGCAGCGTTGGCCAGCTGGGCTTATAGGTGGGGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGAAGGTGTTCGTCTGCTGCCTAGAGA
AAAATCTGAAGTTCAGAATCTACTTCCAGACACTATAACTGAGGAAGAGAAAGAGAGAATATATGGTATTCTTGGACAGGCTGTGTGTCG
GCCGGCGGGGATTCAGGATGAAGATATAACACTTCAGATAACTGAGAGTGAAGACAACGAAGAAGATGACATGGTTGATGTTATCTGGCG
TCAGTTGATATCAAGCTGCCCATGGCTTTCAGAACTTGATGAAAGTGCAACTGAAGGAGTTATTAAAGTGTGGAGGAAAGTTGTAGATAG
AATATTCAGCCTGTACAAACTCTCTTGCAGTGCATACTTTACTTTCCTTAAACTCAACGCTGGTCAAATTCCTTTAGATGAGGATGACCC
TAGGCTGCATTTAAGTCACAGAGTGGAACAGAGCACTGATGACATGATTGTGATGGCCACATTGCGCCTGCTGCGGTTGCTCGTGAAGCA
TGCTGGTGAGCTTCGGCAGTATCTGGAGCACGGCTTGGAGACAACACCCACTGCACCATGGAGAGGAATTATTCCGCAACTTTTCTCACG
CTTAAACCACCCTGAAGTGTATGTGCGCCAAAGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGATTCCCCACATCTCATATTGTATCC
TGCAATAGTGGGTACCATATCGCTTAGTAGTGAATCCCAGGCTTCAGGAAATAAATTTTCCACTGCAATTCCAACTTTACTTGGCAATAT
TCAAGGAGAAGAATTGCTGGTTTCTGAATGTGAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAATAAGGATGAACCTAAAAGTGGATT
AAATGAAGACCAAGCCATGATGCAGGATTGTTACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAACCCCACCATGGTATTACAGGTTCA
GATGCTCGTGGCTGAACTGCGCAGGGTCACTGTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCTGCAACAACACATGTATGTCCTGAG
ACGAATTCAGCAGCTTGAAGATGAGGTGAAGAGAGTCCAGAACAACAACACCTTACGCAAAGAAGAGAAAATTGCAATCATGAGGGAGAA
GCACACAGCTTTGATGAAGCCCATCGTATTTGCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCCTGCAGAAACACCTCATGAAAAATG
GTTTCAGGATAACTATGGTGATGCCATTGAAAATGCCCTAGAAAAACTGAAGACTCCATTGAACCCTGCAAAGCCTGGGAGCAGCTGGAT
TCCATTTAAAGAGATAATGCTAAGTTTGCAACAGAGAGCACAGAAACGTGCAAGTTACATCTTGCGTCTTGAAGAAATCAGTCCATGGTT
GGCTGCCATGACTAACACTGAAATTGCTCTTCCTGGGGAAGTCTCAGCCAGAGACACTGTCACAATCCATAGTGTGGGCGGAACCATCAC
AATCTTACCGACTAAAACCAAGCCAAAGAAACTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCCTTATCTTTTCAAAGGACTGGAGGA
TTTACATCTGGATGAGAGAATAATGCAGTTCCTATCTATTGTGAATACCATGTTTGCTACAATTAATCGCCAAGAAACACCCCGGTTCCA
TGCTCGACACTATTCTGTAACACCACTAGGAACAAGATCAGGACTAATCCAGTGGGTAGATGGAGCCACACCCTTATTTGGTCTTTACAA
ACGATGGCAACAACGGGAAGCTGCCTTACAAGCACAAAAGGCCCAAGATTCCTACCAAACTCCTCAGAATCCTGGAATTGTACCCCGTCC
TAGTGAACTTTATTACAGTAAAATTGGCCCTGCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTCCCGTCGGGATTGGCCTCTTCATGT
AATGAAGGCAGTATTGGAAGAGTTAATGGAGGCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTGGTCATCTTGCACAACACCTGATGA
ATGGTGGAGAGTTACGCAGTCTTATGCAAGATCTACTGCAGTCATGTCTATGGTTGGATACATAATTGGCCTTGGAGACAGACATCTGGA
TAATGTTCTTATAGATATGACGACTGGAGAAGTTGTTCACATAGATTACAATGTTTGCTTTGAAAAAGGTAAAAGCCTTAGAGTTCCTGA
GAAAGTACCTTTTCGAATGACACAAAACATTGAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGTATTTAGGCTTTCATGTGAGCAGGT
TTTACACATTATGCGGCGTGGCAGAGAGACCCTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCCTCTGGTGGACTGGACAGCAGGAGG
CGAGGCTGGGTTTGCTGGTGCTGTCTATGGTGGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAAGAGAGAGATGGAGCGAGAGATCAC
CCGCAGCCTGTTTTCTTCTAGAGTAGCTGAGATTAAGGTGAACTGGTTTAAGAATAGAGATGAGATGCTGGTTGTGCTTCCCAAGTTGGA
CGGTAGCTTAGATGAATACCTAAGCTTGCAAGAGCAACTGACAGATGTGGAAAAACTGCAGGGCAAACTACTGGAGGAAATAGAGTTTCT
AGAAGGAGCTGAAGGGGTGGATCATCCTTCTCATACTCTGCAACACAGGTATTCTGAGCACACCCAACTACAGACTCAGCAAAGAGCTGT
TCAGGAAGCAATCCAGGTGAAGCTGAATGAATTTGAACAATGGATAACACATTATCAGGCTGCATTCAATAATTTAGAAGCAACACAGCT
TGCAAGCTTGCTTCAAGAGATAAGCACACAAATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAACAGCCTTTCTGCAGAATGCTGGTCA
GGCCCACTTGATTAGCCAGTGCGAGCAGCTGGAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCGCTCCGTGCTCCGTGGCTGTCTGGA
GCAACTGCATCACTATGCAACCGTGGCCCTGCAGTATCCGAAGGCCATATTTCAGAAACATCGAATTGAACAGTGGAAGACCTGGATGGA
AGAGCTCATCTGTAACACCACAGTAGAGCGTTGTCAAGAGCTCTATAGGAAATATGAAATGCAATATGCTCCCCAGCCACCCCCAACAGT
GTGTCAGTTCATCACTGCCACTGAAATGACCCTGCAGCGATACGCAGCAGACATCAACAGCAGACTTATTAGACAAGTGGAACGCTTGAA
ACAGGAAGCTGTCACTGTGCCAGTTTGTGAAGATCAGTTGAAAGAAATTGAACGTTGCATTAAAGTTTTCCTTCATGAGAATGGAGAAGA
AGGATCTTTGAGTCTAGCAAGTGTTATTATTTCTGCCCTTTGTACCCTTACAAGGCGTAACCTGATGATGGAAGGTGCAGCGTCAAGTGC
TGGAGAACAGCTGGTTGATCTGACTTCTCGGGATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTATGAGCGGAAACGTCACCTGCTTGGT
TCAGTTACTGAAGCAGTGCCACCTGGTGCCACAGGACTTAGATATCCCGAACCCCATGGAAGCGTCTGAGACAGTTCACTTAGCCAATGG
AGTGTATACCTCACTTCAGGAATTGAATTCGAATTTCCGGCAAATCATATTTCCAGAAGCACTTCGATGTTTAATGAAAGGGGAATACAC
GTTAGAAAGTATGCTGCATGAACTGGACGGTCTTATTGAGCAGACCACCGATGGCGTTCCCCTGCAGACTCTAGTGGAATCTCTTCAGGC
CTACTTAAGAAACGCAGCTATGGGACTGGAAGAAGAAACACATGCTCATTACATCGATGTTGCCAGACTACTACATGCTCAGTACGGTGA
ATTAATCCAACCGAGAAATGGTTCAGTTGATGAAACACCCAAAATGTCAGCTGGCCAGATGCTTTTGGTAGCATTCGATGGCATGTTTGC
TCAAGTTGAAACTGCTTTCAGCTTATTAGTTGAAAAGTTGAACAAGATGGAAATTCCCATAGCTTGGCGAAAGATTGACATCATAAGGGA
AGCCAGGAGTACTCAAGTTAATTTTTTTGATGATGATAATCACCGGCAGGTGCTAGAAGAGATTTTCTTTCTAAAAAGACTACAGACTAT
TAAGGAGTTCTTCAGGCTCTGTGGTACCTTTTCTAAAACATTGTCAGGATCAAGTTCACTTGAAGATCAGAATACTGTGAATGGGCCTGT
ACAGATTGTCAATGTGAAAACCCTTTTTAGAAACTCTTGTTTCAGTGAAGACCAAATGGCCAAACCTATCAAGGCATTCACAGCTGACTT
TGTGAGGCAGCTCTTGATAGGGCTACCCAACCAAGCCCTCGGACTCACACTGTGCAGTTTTATCAGTGCTCTGGGTGTAGACATCATTGC
TCAAGTAGAGGCAAAGGACTTTGGTGCCGAAAGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGCGGTGGAACATAACATCCAGATAGG
GAAGTTCTCTCAGCTGGTTATGAACAGGGCAACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAAGAAGCATGACTTGGTGCGAAGGCT
AGAAACCAGTATTTCTTCTTGTAAGACAAGCCTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCAGTGGCAACATGAAGATCTACTTAT
CAATAGACCACAAGCCATGTCAGTCACACCTCCCCCACGGTCTGCTATCCTAACCAGCATGAAAAAGAAGCTGCATACCCTGAGCCAGAT
TGAAACTTCTATTGCAACAGTTCAGGAGAAGCTAGCTGCACTTGAATCAAGTATTGAACAGCGACTCAAGTGGGCAGGTGGTGCCAACCC
TGCATTGGCCCCTGTACTACAAGATTTTGAAGCAACGATAGCTGAAAGAAGAAATCTTGTCCTTAAAGAGAGCCAAAGAGCAAGTCAGGT
CACATTTCTCTGCAGCAATATCATTCATTTTGAAAGTTTACGAACAAGAACTGCAGAAGCCTTAAACCTGGATGCGGCGTTATTTGAACT
AATCAAGCGATGTCAGCAGATGTGTTCGTTTGCATCACAGTTTAACAGTTCAGTGTCTGAGTTAGAGCTTCGTTTATTACAGAGAGTGGA
CACTGGTCTTGAACATCCTATTGGCAGCTCTGAATGGCTTTTGTCAGCACACAAACAGTTGACCCAGGATATGTCTACTCAGAGGGCAAT
TCAGACAGAGAAAGAGCAGCAGATAGAAACGGTCTGTGAAACAATTCAGAATCTGGTTGATAATATAAAGACTGTGCTCACTGGTCATAA
CCGACAGCTTGGAGATGTCAAACATCTCTTGAAAGCTATGGCTAAGGATGAAGAAGCTGCTCTGGCAGATGGTGAAGATGTTCCCTATGA
GAACAGTGTTAGGCAGTTTTTGGGTGAATATAAATCATGGCAAGACAACATTCAAACAGTTCTATTTACATTAGTCCAGGCTATGGGTCA
GGTTCGAAGTCAAGAACACGTTGAAATGCTCCAGGAAATCACTCCCACCTTGAAAGAACTGAAAACACAAAGTCAGAGTATCTATAATAA
TTTAGTGAGTTTTGCATCACCCTTAGTCACCGATGCAACAAATGAATGTTCGAGTCCAACGTCATCTGCTACTTATCAGCCATCCTTCGC
TGCAGCAGTCCGGAGTAACACTGGCCAGAAGACTCAGCCTGATGTCATGTCACAGAATGCTAGAAAGCTGATCCAAAAAAATCTTGCTAC
ATCAGCTGATACTCCACCAAGCACCGTTCCAGGAACTGGCAAGAGTGTTGCTTGTAGTCCTAAAAAGGCAGTCAGAGACCCTAAAACTGG
GAAAGCGGTGCAAGAGAGAAACTCCTATGCAGTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTTAGAGGGCCGAGATGTTGATCCGAATAG
GAGGATGTCAGTTGCTGAACAGGTTGACTATGTCATTAAGGAAGCAACTAATCTAGATAACTTGGCTCAGCTGTATGAAGGTTGGACAGC
CTGGGTGTGAATGGCAAGACAGTAGATGAGTCTGGTTAAGCGAGGTCAGACATCCACCAGAATCAACTCAGCCTCAGGCATCCAAAGCCA
CACCACAGTCGGTGGTGATGCAACTGGGGGCTTACTCTGAGGAAACCTAGGAAATCTCGGTGCACTAGGAAGTGAATCCCGCAGGACAGC
TGCACTCAGGGATACGCCCAACACCATGGCCTGCAACCCCAGGGTCAAGGGTGAAGGAAAGCAAGCTCACCGCCTGAACACGGAGATTGT
CTTTCTGCCACAGAACAGCAGCAGACGTGTCGGGAGGTTAGCTGCGGAAAGAAATCGGGATGCCGCGGAGCACAGAGTGATTTGGAACTC
CATTCCACCTGACCCTGTGTGTACAATCCAGGAAAAAAACAAACCCCACTCAGAAACAGAGAAAACTGGGGTCGCGAAGAAATCACAGCC
AAGGAAGATTTGATGCATTCAGATTCTCGTGTAACACTTGTTGCTTGGCAACAGTACTGGTTGGGTTGACCAGTAAGTAGAAAAAGGCTA
AAGGCTATGCGATATGAATTTCAGAAATGGACTGAAAATGGAGAGCTATGTAACAGATACACTACAGTAGAAGAACTTACTTCTGAAATG
AAGGGAAAAAAACCACCCCATCGTTCCCTACTCCTCCCCACCACTTACCCGTTCCCCCTTTACCTAATCTAGTAGATTAGCCATCTTTCA
AATTCACTTTTATTTCAGTCCTTATATTTCATATACTTCCGTCTCGATGCTGTTAACAACTTCTGATAACATGGAAAATTCAAGGATTGT
TTAAAGGTCTGATGATCACACACAAAATGTAATTCCGGTTATTTAAGTCATTTCTGTGATTCTATCATGTACAGTTTCCAGAATTGTCAC
TGTGCATTCAAAAGTAATGAATCTAACAGACATTTGATTTAATGTACACTCCCTTTTGCTTATAGTGTGCATTTTTTTTGGAGGTCATTC
AAATTTTCCCTCTTCTGTGATAGCTGTAGTTTCTTTCATAGAAAGTAGCTAATCCAGTGTAATCTTTTACCTTTTTAAAAACCAAGATAG
AGTATCTATTAGAGTTTTACATTGTTGATGATAGATTAACAATAAAGTGATGTTCTGGTGGAGGTAGACTGAAATTTTTTTAATTCATGT
TTTTCATTTGATACTTTTAATTTACACTTAGTAAATTAAAAGTTGTTTAATTTACTTGGCATTTTAGGACATGTACATGAAACAGTGAAA
ATGAGATCCACCAACATCTTTTATTAAGTTCAGTTATTAGTCTGTGAAGTGCTTTACTTTTTGCACAATTTTAATAGCTTGCTATTCAGT
AATACATTATAGTGAATTCATGATCAAGGTTTCCTTAAATTTAGCATTGCATTTCAGTACTGACTGTGTAAGCTAAATTGCTGATCCAAA
ATAAAAACCCAGACTAGAATAGGGTTCTTAAAATCAAGTATCAATACAAAATAGAACACAATTAAAATCTTAATTGTTGGCTGGGCACAG
TGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCATGAGGTTAGGAGAGCGAGACCATCCTGGCTAACACGGTG
AAACCCCGTCTTTACTAAAAATACAAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGG
AGAATGGCGTGAACCCAGGAGGCGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGCTAGACTCTGTGT
CAAAAATAAATGACTAGATAAAAAAAAAAATTGTTTGAGTACATTTTCCCTGCATTTTAGAGATTAGGACAGTGGTCACTTTCTAGTTGC
CGTCTTCACAGACAAACTTGAAAGGTATTAAGGAAAAAATTCCACATAGCTCTGGGCCTTTTTTGTATTCTGATTGCCACGTTAATCTGT
AATCGTTAAGTACCCATGAAAGAATGTGTTTCAGTATCAGTGCTTTTTTGGTACTTTAACAAGTATTGTAGGCACGGTGGATTTTTTTGA
AATACCCATGTGTCCAATAGCAAGTTAAGGAACCTAGCGCATCAAATTTTGTTTTCTTCATTCATTTGGAACCTTATTTTCGCAAAAAAC
CTAGCTGGAATAATAATGCCATATTGTATTTTGCACACTGCTTTATTTTCTAGAGGCTCTGGGAGCAAATTACATTCATCACATTACCTC
TGCTCTCTCAAGATTAAAGTCTTTCAGCAACATTCTTTATTGTCATCATAAGGAAAAACTTTTATCGCAATGATAGTCAGTTCACATTAG
TTTAGCACTATAGATAGTATTCAGAAATTGCTTTCTCTTTGGTAAAGAAGATAAATAGGTGAATTTTATTGCCTGTGTTTTCAGGCTTCA
GAGGTACCTGGCACCTTACTCAAGCAAAAACAAAAAACAGCTTTACTTCAAAAGCATGTGCCTCTGGTAAATTATCCATCACTTTTGTTT
TAAAGTGGTCCCTCCAAGAATAATGTGGCATACACAGTGGGTTTGGTTGTAAGGCAGATGTAATAGATGACTTCAAAAGCCTGCTCCTTA
CTGCACTCTGGACAAGGCCCTGGTCTGTATAGTTTGGCTTCCTCTGTTAAGTCATTCTACAAGGTGACTTGCCATTTGAACTTTCGTAAG
AGACCTCAGCAGTTAGACTGAGAAAAGTTAGAGTGCTGTAGTTATGAAGTCATACATTTTTGATAAAATACCTGTGGAAAACCAGGGATC
CTCTCCTGTTTCTCTCTCTTGCCTCCCCCTTTCCCTCCATTCCTCTGTCGCCTCCCCCTCTCCTCCACTTTCTTTAAGAATCAGGGGGTA
CAGAATAACCTACAAACAACCTCTTCAAAGTACCCTTGGAAATTGAAGTTCAATCTTAAGTTTTTTGCTGTCTTTAATTTACTAGAATTG
CCTAATTTTTAGTTGATTTCTCTACAGAGCTTAGCTTGTGTAGTTATTTCTCTTTTACTGTTGCTTTGGTGTGTCTTGAAGTTTGATTGA
TTATTTTTGGTCATTGAGTTCTTAGTGTAGTTTGCTAGATGATTATTAAGATTCTTTTGTGTCTGACACTTGTGGTGAGTTGCTTTTGAA
ATCTGTTGAGATTTCCATGTGAGAACTGATAATCAGGCTCTTGATCTGCTTCCCTAAATTACTTTTTTAGAGCCCAAACCCCAGGTTTAG
GGTGAGGGTTTGTAATACAAAGAAACACTTCCATCACTTCTGCCCTTAACCCTTGCCTCTATTACCTAAGCTTAGTAAGTAGTTTTCTTA
ATATTGTCCAATGTTTGGTGTTATCTGCATTGTTTTTTGTTTTTTTAATTGTGGTTGTTCTGACGTGTGAAATTTAAGGAAAGAGCCATT
TTTTAAAAATGCCGAGCAGGGCAATGCAAGTACAGCCAAATATTAGACTTGATGTGCAATCTTCGGTCCTTTTTAATCTGGGGTATTATA
GGCAGTACTTTAAATTGCAAAGTCTTCCGGGCCTATTTTCCTCTACATTTTTGTAATTAACTCTGGGGGCTTACTTGTTTTGGCAGTACT
GAAATCAAAGGAGCTGGTTCTTCTTTTCTCCCAATTATTTTCATATGAAAGCACCTACAATTAGCCTGTTAGTCCTATTCAGATACATCA
AATATCAGTGAATGCTTTACTATTCGCACATTTAAGCATCTTTGTTTTACATAAAATTAGAGTATGAAAACCAGTGTTCAATTTTTTATC
TTGTTGAGCTTGTAAAATGCCAGCAATTTAAAACTAGGACTTTTCCCCCCATAAGCCAAGGAGGTAGAATTACTAATACAAGGGTTAAAG
AAGGTAGATTTTGTTTTCAATATTTGGGTAATATTAGAAAGATTCTTCCCACAGGGAAGAACTAGCAAGTGTCCCAATTTTTTCCAAACG
TTGGGGAGGGGAAAATTCACTGTATCATGAAACCCTAAGGGTTTGTTGCACTTCCTGCTTTTTAGGCCTGGATAACAGTATCACCATCCT
TATTTACAGAAGGGTAAAACTGACTCTTAATGAGAAAAGCTTTATAAGTTCAAGGGCTGTAAAATATGAACTACTTAGGGTCGTTTGCCT
TCCATGGGAACTTGGCTAGACTTAGAAAAAGCTGTTTGTTGTGCTAATGTAAAAGTGTCATACAATTTAGAAGATTTTTGAAGATGGTAA
ACTTAGAAGAATTCTATGTTCTGAAATGCACACTTTTAGAATGTTTTTCTTTGAAAACAGGCTAATAGTTTTTTCTTTTTTTGACAAAGT
TTCAGCTCCTCTTTAAAGTTATTGTGTCATTTTTCTGGTTTAAATTTCCCTTATATTTCCACCTGTAATGTCAGTGGCAACAACATCATA
CTTCACTTACTTGTTAATTTACTTTTTACCCTTATTCTAAGAGCAAGTTGAGTTGAACTGAATCTTCCTTGTCTTAGTAACAATGTATAA
ATAGTGGCTTTTCTGTACAAAAGGTTGTAATGCCTCCTGATGGATATAATTTTGTGATTGTATTTAAAAGTTGAATAAATCACACCAGCT
TCCTGAAAATGTTCATAATGCATCTTTTGGAAAACAAATACATGCCTACTTTGTGCATATTTGCATTAACATGGCAAAGATTGTATGAAA

>5042_5042_6_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000421017_SMG1_chr16_18883946_ENST00000446231_length(amino acids)=3227AA_BP=196
MSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFAYQRRTKKELASALKSA
LSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRA
EDGSVIDYELIDQDARMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSSSSPSLFDGAVISTVTTATK
KHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLPDDL
LQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDVISFILYGNSHRTGKDNWLE
RLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDEGHG
NNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLS
QGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLANAGR
NSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIKSLSSFESGKFVE
CTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQSITENVVKYLKQTSRIAIGP
LRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQLLEKIKEQTVPIRSHLMEL
GLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAGQSTHAMEMLSSCAISFCKS
VKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIESESTVHIGVGEPDFILGQL
YHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQAVCRPAGIQDEDITLQITE
SEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLDEDDPRLHLSHRVEQSTDDM
IVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHLILYPAIVGTISLSSESQAS
GNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMVLQVQMLVAELRRVTVLWDE
LWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETPHEKWFQDNYGDAIENALEK
LKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVGGTITILPTKTKPKKLLFLG
SDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLFGLYKRWQQREAALQAQKAQ
DSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCTTPDEWWRVTQSYARSTAVM
SMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLSCEQVLHIMRRGRETLLTLL
EAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVLPKLDGSLDEYLSLQEQLTD
VEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEATQLASLLQEISTQMDLGP
PSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWKTWMEELICNTTVERCQELY
RKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHENGEEGSLSLASVIISALCT
LTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVHLANGVYTSLQELNSNFRQI
IFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQYGELIQPRNGSVDETPKM
SAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKRLQTIKEFFRLCGTFSKTLS
GSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGVDIIAQVEAKDFGAESKVSV
DDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQWQHEDLLINRPQAMSVTPPPRSA
ILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQRASQVTFLCSNIIHFESLRT
RTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMSTQRAIQTEKEQQIETVCETI
QNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQAMGQVRSQEHVEMLQEITP
TLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQKNLATSADTPPSTVPGTGKS

--------------------------------------------------------------
>5042_5042_7_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000451270_SMG1_chr16_18883946_ENST00000389467_length(transcript)=14515nt_BP=700nt
GCCTCGCCTAGGGAGGATGTGGCGGGTATAAAAGCCCCACCCAGGCCAGCCGGCTCTGCTCAGCATTTGGGGACGCTCTCAGCTCTCGGC
GCACGGCCCAGCTTCCTTCAAAATGTCTACTGTTCACGAAATCCTGTGCAAGCTCAGCTTGGAGGGTGATCACTCTACACCCCCAAGTGC
ATATGGGTCTGTCAAAGCCTATACTAACTTTGATGCTGAGCGGGATGCTTTGAACATTGAAACAGCCATCAAGACCAAAGGTGTGGATGA
GGTCACCATTGTCAACATTTTGACCAACCGCAGCAATGCACAGAGACAGGATATTGCCTTCGCCTACCAGAGAAGGACCAAAAAGGAACT
TGCATCAGCACTGAAGTCAGCCTTATCTGGCCACCTGGAGACGGTGATTTTGGGCCTATTGAAGACACCTGCTCAGTATGACGCTTCTGA
GCTAAAAGCTTCCATGAAGGGGCTGGGAACCGACGAGGACTCTCTCATTGAGATCATCTGCTCCAGAACCAACCAGGAGCTGCAGGAAAT
TAACAGAGTCTACAAGGAAATGTACAAGACTGATCTGGAGAAGGACATTATTTCGGACACATCTGGTGACTTCCGCAAGCTGATGGTTGC
CCTGGCAAAGGGTAGAAGAGCAGAGGATGGCTCTGTCATTGATTATGAACTGATTGACCAAGATGCTCGGATGTGGGCGCTATCTCCAAC
TGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACAC
ATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAG
CACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACAC
GAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTT
CCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTC
CTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATT
TGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAG
TCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAAC
AGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAA
GACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCA
AGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGC
AGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGC
ATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCT
AACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGA
GATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGA
AGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAG
GTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCT
CACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGA
CTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCA
GAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTT
TGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAA
AATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTC
TGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAAC
ATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTC
ATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACA
GCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGAACAAACAGTCCCAAT
TAGAAGCCATCTCATGGAATTAGGTCTAACAGCAGCAAAATTTGCTAGAAAACGAGGGAATGTGTCCCTTGCAACAAGACTGCTGGCACA
GTGCAGTGAAGTTCAGCTGGGAAAGACCACCACTGCACAGGATTTAGTCCAACATTTTAAAAAACTATCAACCCAAGGTCAAGTGGATGA
AAAATGGGGGCCCGAACTTGATATTGAAAAAACCAAATTGCTTTATACAGCAGGCCAGTCAACACATGCAATGGAAATGTTGAGTTCTTG
TGCCATATCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGTTGCTAAATCAATTCTGACACTGGCTAAATGGATCCAGGCAGAATGGAA
AGAGATTTCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCACCAACAGAACTTCACAGGTCTTTCTACTTTGTCTAAAAACATACTCAC
TCTAATAGAACTGCCATCTGTTAATACGATGGAAGAAGAGTATCCTCGGATCGAGAGTGAATCTACAGTGCATATTGGAGTTGGAGAACC
TGACTTCATTTTGGGACAGTTGTATCACCTGTCTTCAGTACAGGCACCTGAAGTAGCCAAATCTTGGGCAGCGTTGGCCAGCTGGGCTTA
TAGGTGGGGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGAAGGTGTTCGTCTGCTGCCTAGAGAAAAATCTGAAGTTCAGAATCTACT
TCCAGACACTATAACTGAGGAAGAGAAAGAGAGAATATATGGTATTCTTGGACAGGCTGTGTGTCGGCCGGCGGGGATTCAGGATGAAGA
TATAACACTTCAGATAACTGAGAGTGAAGACAACGAAGAAGATGACATGGTTGATGTTATCTGGCGTCAGTTGATATCAAGCTGCCCATG
GCTTTCAGAACTTGATGAAAGTGCAACTGAAGGAGTTATTAAAGTGTGGAGGAAAGTTGTAGATAGAATATTCAGCCTGTACAAACTCTC
TTGCAGTGCATACTTTACTTTCCTTAAACTCAACGCTGGTCAAATTCCTTTAGATGAGGATGACCCTAGGCTGCATTTAAGTCACAGAGT
GGAACAGAGCACTGATGACATGATTGTGATGGCCACATTGCGCCTGCTGCGGTTGCTCGTGAAGCATGCTGGTGAGCTTCGGCAGTATCT
GGAGCACGGCTTGGAGACAACACCCACTGCACCATGGAGAGGAATTATTCCGCAACTTTTCTCACGCTTAAACCACCCTGAAGTGTATGT
GCGCCAAAGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGATTCCCCACATCTCATATTGTATCCTGCAATAGTGGGTACCATATCGCT
TAGTAGTGAATCCCAGGCTTCAGGAAATAAATTTTCCACTGCAATTCCAACTTTACTTGGCAATATTCAAGGAGAAGAATTGCTGGTTTC
TGAATGTGAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAATAAGGATGAACCTAAAAGTGGATTAAATGAAGACCAAGCCATGATGCA
GGATTGTTACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAACCCCACCATGGTATTACAGGTTCAGATGCTCGTGGCTGAACTGCGCAG
GGTCACTGTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCTGCAACAACACATGTATGTCCTGAGACGAATTCAGCAGCTTGAAGATGA
GGTGAAGAGAGTCCAGAACAACAACACCTTACGCAAAGAAGAGAAAATTGCAATCATGAGGGAGAAGCACACAGCTTTGATGAAGCCCAT
CGTATTTGCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCCTGCAGAAACACCTCATGAAAAATGGTTTCAGGATAACTATGGTGATGC
CATTGAAAATGCCCTAGAAAAACTGAAGACTCCATTGAACCCTGCAAAGCCTGGGAGCAGCTGGATTCCATTTAAAGAGATAATGCTAAG
TTTGCAACAGAGAGCACAGAAACGTGCAAGTTACATCTTGCGTCTTGAAGAAATCAGTCCATGGTTGGCTGCCATGACTAACACTGAAAT
TGCTCTTCCTGGGGAAGTCTCAGCCAGAGACACTGTCACAATCCATAGTGTGGGCGGAACCATCACAATCTTACCGACTAAAACCAAGCC
AAAGAAACTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCCTTATCTTTTCAAAGGACTGGAGGATTTACATCTGGATGAGAGAATAAT
GCAGTTCCTATCTATTGTGAATACCATGTTTGCTACAATTAATCGCCAAGAAACACCCCGGTTCCATGCTCGACACTATTCTGTAACACC
ACTAGGAACAAGATCAGGACTAATCCAGTGGGTAGATGGAGCCACACCCTTATTTGGTCTTTACAAACGATGGCAACAACGGGAAGCTGC
CTTACAAGCACAAAAGGCCCAAGATTCCTACCAAACTCCTCAGAATCCTGGAATTGTACCCCGTCCTAGTGAACTTTATTACAGTAAAAT
TGGCCCTGCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTCCCGTCGGGATTGGCCTCTTCATGTAATGAAGGCAGTATTGGAAGAGTT
AATGGAGGCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTGGTCATCTTGCACAACACCTGATGAATGGTGGAGAGTTACGCAGTCTTA
TGCAAGATCTACTGCAGTCATGTCTATGGTTGGATACATAATTGGCCTTGGAGACAGACATCTGGATAATGTTCTTATAGATATGACGAC
TGGAGAAGTTGTTCACATAGATTACAATGTTTGCTTTGAAAAAGGTAAAAGCCTTAGAGTTCCTGAGAAAGTACCTTTTCGAATGACACA
AAACATTGAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGTATTTAGGCTTTCATGTGAGCAGGTTTTACACATTATGCGGCGTGGCAG
AGAGACCCTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCCTCTGGTGGACTGGACAGCAGGAGGCGAGGCTGGGTTTGCTGGTGCTGT
CTATGGTGGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAAGAGAGAGATGGAGCGAGAGATCACCCGCAGCCTGTTTTCTTCTAGAGT
AGCTGAGATTAAGGTGAACTGGTTTAAGAATAGAGATGAGATGCTGGTTGTGCTTCCCAAGTTGGACGGTAGCTTAGATGAATACCTAAG
CTTGCAAGAGCAACTGACAGATGTGGAAAAACTGCAGGGCAAACTACTGGAGGAAATAGAGTTTCTAGAAGGAGCTGAAGGGGTGGATCA
TCCTTCTCATACTCTGCAACACAGGTATTCTGAGCACACCCAACTACAGACTCAGCAAAGAGCTGTTCAGGAAGCAATCCAGGTGAAGCT
GAATGAATTTGAACAATGGATAACACATTATCAGGCTGCATTCAATAATTTAGAAGCAACACAGCTTGCAAGCTTGCTTCAAGAGATAAG
CACACAAATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAACAGCCTTTCTGCAGAATGCTGGTCAGGCCCACTTGATTAGCCAGTGCGA
GCAGCTGGAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCGCTCCGTGCTCCGTGGCTGTCTGGAGCAACTGCATCACTATGCAACCGT
GGCCCTGCAGTATCCGAAGGCCATATTTCAGAAACATCGAATTGAACAGTGGAAGACCTGGATGGAAGAGCTCATCTGTAACACCACAGT
AGAGCGTTGTCAAGAGCTCTATAGGAAATATGAAATGCAATATGCTCCCCAGCCACCCCCAACAGTGTGTCAGTTCATCACTGCCACTGA
AATGACCCTGCAGCGATACGCAGCAGACATCAACAGCAGACTTATTAGACAAGTGGAACGCTTGAAACAGGAAGCTGTCACTGTGCCAGT
TTGTGAAGATCAGTTGAAAGAAATTGAACGTTGCATTAAAGTTTTCCTTCATGAGAATGGAGAAGAAGGATCTTTGAGTCTAGCAAGTGT
TATTATTTCTGCCCTTTGTACCCTTACAAGGCGTAACCTGATGATGGAAGGTGCAGCGTCAAGTGCTGGAGAACAGCTGGTTGATCTGAC
TTCTCGGGATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTATGAGCGGAAACGTCACCTGCTTGGTTCAGTTACTGAAGCAGTGCCACCT
GGTGCCACAGGACTTAGATATCCCGAACCCCATGGAAGCGTCTGAGACAGTTCACTTAGCCAATGGAGTGTATACCTCACTTCAGGAATT
GAATTCGAATTTCCGGCAAATCATATTTCCAGAAGCACTTCGATGTTTAATGAAAGGGGAATACACGTTAGAAAGTATGCTGCATGAACT
GGACGGTCTTATTGAGCAGACCACCGATGGCGTTCCCCTGCAGACTCTAGTGGAATCTCTTCAGGCCTACTTAAGAAACGCAGCTATGGG
ACTGGAAGAAGAAACACATGCTCATTACATCGATGTTGCCAGACTACTACATGCTCAGTACGGTGAATTAATCCAACCGAGAAATGGTTC
AGTTGATGAAACACCCAAAATGTCAGCTGGCCAGATGCTTTTGGTAGCATTCGATGGCATGTTTGCTCAAGTTGAAACTGCTTTCAGCTT
ATTAGTTGAAAAGTTGAACAAGATGGAAATTCCCATAGCTTGGCGAAAGATTGACATCATAAGGGAAGCCAGGAGTACTCAAGTTAATTT
TTTTGATGATGATAATCACCGGCAGGTGCTAGAAGAGATTTTCTTTCTAAAAAGACTACAGACTATTAAGGAGTTCTTCAGGCTCTGTGG
TACCTTTTCTAAAACATTGTCAGGATCAAGTTCACTTGAAGATCAGAATACTGTGAATGGGCCTGTACAGATTGTCAATGTGAAAACCCT
TTTTAGAAACTCTTGTTTCAGTGAAGACCAAATGGCCAAACCTATCAAGGCATTCACAGCTGACTTTGTGAGGCAGCTCTTGATAGGGCT
ACCCAACCAAGCCCTCGGACTCACACTGTGCAGTTTTATCAGTGCTCTGGGTGTAGACATCATTGCTCAAGTAGAGGCAAAGGACTTTGG
TGCCGAAAGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGCGGTGGAACATAACATCCAGATAGGGAAGTTCTCTCAGCTGGTTATGAA
CAGGGCAACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAAGAAGCATGACTTGGTGCGAAGGCTAGAAACCAGTATTTCTTCTTGTAA
GACAAGCCTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCAGCAGTGGCAACATGAAGATCTACTTATCAATAGACCACAAGCCATGTC
AGTCACACCTCCCCCACGGTCTGCTATCCTAACCAGCATGAAAAAGAAGCTGCATACCCTGAGCCAGATTGAAACTTCTATTGCAACAGT
TCAGGAGAAGCTAGCTGCACTTGAATCAAGTATTGAACAGCGACTCAAGTGGGCAGGTGGTGCCAACCCTGCATTGGCCCCTGTACTACA
AGATTTTGAAGCAACGATAGCTGAAAGAAGAAATCTTGTCCTTAAAGAGAGCCAAAGAGCAAGTCAGGTCACATTTCTCTGCAGCAATAT
CATTCATTTTGAAAGTTTACGAACAAGAACTGCAGAAGCCTTAAACCTGGATGCGGCGTTATTTGAACTAATCAAGCGATGTCAGCAGAT
GTGTTCGTTTGCATCACAGTTTAACAGTTCAGTGTCTGAGTTAGAGCTTCGTTTATTACAGAGAGTGGACACTGGTCTTGAACATCCTAT
TGGCAGCTCTGAATGGCTTTTGTCAGCACACAAACAGTTGACCCAGGATATGTCTACTCAGAGGGCAATTCAGACAGAGAAAGAGCAGCA
GATAGAAACGGTCTGTGAAACAATTCAGAATCTGGTTGATAATATAAAGACTGTGCTCACTGGTCATAACCGACAGCTTGGAGATGTCAA
ACATCTCTTGAAAGCTATGGCTAAGGATGAAGAAGCTGCTCTGGCAGATGGTGAAGATGTTCCCTATGAGAACAGTGTTAGGCAGTTTTT
GGGTGAATATAAATCATGGCAAGACAACATTCAAACAGTTCTATTTACATTAGTCCAGGCTATGGGTCAGGTTCGAAGTCAAGAACACGT
TGAAATGCTCCAGGAAATCACTCCCACCTTGAAAGAACTGAAAACACAAAGTCAGAGTATCTATAATAATTTAGTGAGTTTTGCATCACC
CTTAGTCACCGATGCAACAAATGAATGTTCGAGTCCAACGTCATCTGCTACTTATCAGCCATCCTTCGCTGCAGCAGTCCGGAGTAACAC
TGGCCAGAAGACTCAGCCTGATGTCATGTCACAGAATGCTAGAAAGCTGATCCAAAAAAATCTTGCTACATCAGCTGATACTCCACCAAG
CACCGTTCCAGGAACTGGCAAGAGTGTTGCTTGTAGTCCTAAAAAGGCAGTCAGAGACCCTAAAACTGGGAAAGCGGTGCAAGAGAGAAA
CTCCTATGCAGTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTTAGAGGGCCGAGATGTTGATCCGAATAGGAGGATGTCAGTTGCTGAACA
GGTTGACTATGTCATTAAGGAAGCAACTAATCTAGATAACTTGGCTCAGCTGTATGAAGGTTGGACAGCCTGGGTGTGAATGGCAAGACA
GTAGATGAGTCTGGTTAAGCGAGGTCAGACATCCACCAGAATCAACTCAGCCTCAGGCATCCAAAGCCACACCACAGTCGGTGGTGATGC
AACTGGGGGCTTACTCTGAGGAAACCTAGGAAATCTCGGTGCACTAGGAAGTGAATCCCGCAGGACAGCTGCACTCAGGGATACGCCCAA
CACCATGGCCTGCAACCCCAGGGTCAAGGGTGAAGGAAAGCAAGCTCACCGCCTGAACACGGAGATTGTCTTTCTGCCACAGAACAGCAG
CAGACGTGTCGGGAGGTTAGCTGCGGAAAGAAATCGGGATGCCGCGGAGCACAGAGTGATTTGGAACTCCATTCCACCTGACCCTGTGTG
TACAATCCAGGAAAAAAACAAACCCCACTCAGAAACAGAGAAAACTGGGGTCGCGAAGAAATCACAGCCAAGGAAGATTTGATGCATTCA
GATTCTCGTGTAACACTTGTTGCTTGGCAACAGTACTGGTTGGGTTGACCAGTAAGTAGAAAAAGGCTAAAGGCTATGCGATATGAATTT
CAGAAATGGACTGAAAATGGAGAGCTATGTAACAGATACACTACAGTAGAAGAACTTACTTCTGAAATGAAGGGAAAAAAACCACCCCAT
CGTTCCCTACTCCTCCCCACCACTTACCCGTTCCCCCTTTACCTAATCTAGTAGATTAGCCATCTTTCAAATTCACTTTTATTTCAGTCC
TTATATTTCATATACTTCCGTCTCGATGCTGTTAACAACTTCTGATAACATGGAAAATTCAAGGATTGTTTAAAGGTCTGATGATCACAC
ACAAAATGTAATTCCGGTTATTTAAGTCATTTCTGTGATTCTATCATGTACAGTTTCCAGAATTGTCACTGTGCATTCAAAAGTAATGAA
TCTAACAGACATTTGATTTAATGTACACTCCCTTTTGCTTATAGTGTGCATTTTTTTTGGAGGTCATTCAAATTTTCCCTCTTCTGTGAT
AGCTGTAGTTTCTTTCATAGAAAGTAGCTAATCCAGTGTAATCTTTTACCTTTTTAAAAACCAAGATAGAGTATCTATTAGAGTTTTACA
TTGTTGATGATAGATTAACAATAAAGTGATGTTCTGGTGGAGGTAGACTGAAATTTTTTTAATTCATGTTTTTCATTTGATACTTTTAAT
TTACACTTAGTAAATTAAAAGTTGTTTAATTTACTTGGCATTTTAGGACATGTACATGAAACAGTGAAAATGAGATCCACCAACATCTTT
TATTAAGTTCAGTTATTAGTCTGTGAAGTGCTTTACTTTTTGCACAATTTTAATAGCTTGCTATTCAGTAATACATTATAGTGAATTCAT
GATCAAGGTTTCCTTAAATTTAGCATTGCATTTCAGTACTGACTGTGTAAGCTAAATTGCTGATCCAAAATAAAAACCCAGACTAGAATA
GGGTTCTTAAAATCAAGTATCAATACAAAATAGAACACAATTAAAATCTTAATTGTTGGCTGGGCACAGTGGCTCACGCCTGTAATCCCA
GCACTTTGGGAGGCCGAGGCGGGCGGATCATGAGGTTAGGAGAGCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTTTACTAAAAA
TACAAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAG
GCGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGCTAGACTCTGTGTCAAAAATAAATGACTAGATAA
AAAAAAAAATTGTTTGAGTACATTTTCCCTGCATTTTAGAGATTAGGACAGTGGTCACTTTCTAGTTGCCGTCTTCACAGACAAACTTGA
AAGGTATTAAGGAAAAAATTCCACATAGCTCTGGGCCTTTTTTGTATTCTGATTGCCACGTTAATCTGTAATCGTTAAGTACCCATGAAA
GAATGTGTTTCAGTATCAGTGCTTTTTTGGTACTTTAACAAGTATTGTAGGCACGGTGGATTTTTTTGAAATACCCATGTGTCCAATAGC
AAGTTAAGGAACCTAGCGCATCAAATTTTGTTTTCTTCATTCATTTGGAACCTTATTTTCGCAAAAAACCTAGCTGGAATAATAATGCCA
TATTGTATTTTGCACACTGCTTTATTTTCTAGAGGCTCTGGGAGCAAATTACATTCATCACATTACCTCTGCTCTCTCAAGATTAAAGTC
TTTCAGCAACATTCTTTATTGTCATCATAAGGAAAAACTTTTATCGCAATGATAGTCAGTTCACATTAGTTTAGCACTATAGATAGTATT
CAGAAATTGCTTTCTCTTTGGTAAAGAAGATAAATAGGTGAATTTTATTGCCTGTGTTTTCAGGCTTCAGAGGTACCTGGCACCTTACTC
AAGCAAAAACAAAAAACAGCTTTACTTCAAAAGCATGTGCCTCTGGTAAATTATCCATCACTTTTGTTTTAAAGTGGTCCCTCCAAGAAT
AATGTGGCATACACAGTGGGTTTGGTTGTAAGGCAGATGTAATAGATGACTTCAAAAGCCTGCTCCTTACTGCACTCTGGACAAGGCCCT
GGTCTGTATAGTTTGGCTTCCTCTGTTAAGTCATTCTACAAGGTGACTTGCCATTTGAACTTTCGTAAGAGACCTCAGCAGTTAGACTGA
GAAAAGTTAGAGTGCTGTAGTTATGAAGTCATACATTTTTGATAAAATACCTGTGGAAAACCAGGGATCCTCTCCTGTTTCTCTCTCTTG
CCTCCCCCTTTCCCTCCATTCCTCTGTCGCCTCCCCCTCTCCTCCACTTTCTTTAAGAATCAGGGGGTACAGAATAACCTACAAACAACC
TCTTCAAAGTACCCTTGGAAATTGAAGTTCAATCTTAAGTTTTTTGCTGTCTTTAATTTACTAGAATTGCCTAATTTTTAGTTGATTTCT
CTACAGAGCTTAGCTTGTGTAGTTATTTCTCTTTTACTGTTGCTTTGGTGTGTCTTGAAGTTTGATTGATTATTTTTGGTCATTGAGTTC
TTAGTGTAGTTTGCTAGATGATTATTAAGATTCTTTTGTGTCTGACACTTGTGGTGAGTTGCTTTTGAAATCTGTTGAGATTTCCATGTG
AGAACTGATAATCAGGCTCTTGATCTGCTTCCCTAAATTACTTTTTTAGAGCCCAAACCCCAGGTTTAGGGTGAGGGTTTGTAATACAAA
GAAACACTTCCATCACTTCTGCCCTTAACCCTTGCCTCTATTACCTAAGCTTAGTAAGTAGTTTTCTTAATATTGTCCAATGTTTGGTGT
TATCTGCATTGTTTTTTGTTTTTTTAATTGTGGTTGTTCTGACGTGTGAAATTTAAGGAAAGAGCCATTTTTTAAAAATGCCGAGCAGGG
CAATGCAAGTACAGCCAAATATTAGACTTGATGTGCAATCTTCGGTCCTTTTTAATCTGGGGTATTATAGGCAGTACTTTAAATTGCAAA
GTCTTCCGGGCCTATTTTCCTCTACATTTTTGTAATTAACTCTGGGGGCTTACTTGTTTTGGCAGTACTGAAATCAAAGGAGCTGGTTCT
TCTTTTCTCCCAATTATTTTCATATGAAAGCACCTACAATTAGCCTGTTAGTCCTATTCAGATACATCAAATATCAGTGAATGCTTTACT
ATTCGCACATTTAAGCATCTTTGTTTTACATAAAATTAGAGTATGAAAACCAGTGTTCAATTTTTTATCTTGTTGAGCTTGTAAAATGCC
AGCAATTTAAAACTAGGACTTTTCCCCCCATAAGCCAAGGAGGTAGAATTACTAATACAAGGGTTAAAGAAGGTAGATTTTGTTTTCAAT
ATTTGGGTAATATTAGAAAGATTCTTCCCACAGGGAAGAACTAGCAAGTGTCCCAATTTTTTCCAAACGTTGGGGAGGGGAAAATTCACT
GTATCATGAAACCCTAAGGGTTTGTTGCACTTCCTGCTTTTTAGGCCTGGATAACAGTATCACCATCCTTATTTACAGAAGGGTAAAACT
GACTCTTAATGAGAAAAGCTTTATAAGTTCAAGGGCTGTAAAATATGAACTACTTAGGGTCGTTTGCCTTCCATGGGAACTTGGCTAGAC
TTAGAAAAAGCTGTTTGTTGTGCTAATGTAAAAGTGTCATACAATTTAGAAGATTTTTGAAGATGGTAAACTTAGAAGAATTCTATGTTC
TGAAATGCACACTTTTAGAATGTTTTTCTTTGAAAACAGGCTAATAGTTTTTTCTTTTTTTGACAAAGTTTCAGCTCCTCTTTAAAGTTA
TTGTGTCATTTTTCTGGTTTAAATTTCCCTTATATTTCCACCTGTAATGTCAGTGGCAACAACATCATACTTCACTTACTTGTTAATTTA
CTTTTTACCCTTATTCTAAGAGCAAGTTGAGTTGAACTGAATCTTCCTTGTCTTAGTAACAATGTATAAATAGTGGCTTTTCTGTACAAA
AGGTTGTAATGCCTCCTGATGGATATAATTTTGTGATTGTATTTAAAAGTTGAATAAATCACACCAGCTTCCTGAAAATGTTCATAATGC
ATCTTTTGGAAAACAAATACATGCCTACTTTGTGCATATTTGCATTAACATGGCAAAGATTGTATGAAATACCTGTTTTTCAGAAAATAA

>5042_5042_7_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000451270_SMG1_chr16_18883946_ENST00000389467_length(amino acids)=3247AA_BP=215
MLSIWGRSQLSAHGPASFKMSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDI
AFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIIS
DTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSS
SSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNI
CLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDV
ISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTL
NPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPA
VTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGV
DCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLK
ADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQS
ITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQ
LLEKIKEQTVPIRSHLMELGLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAG
QSTHAMEMLSSCAISFCKSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIE
SESTVHIGVGEPDFILGQLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQ
AVCRPAGIQDEDITLQITESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLD
EDDPRLHLSHRVEQSTDDMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHL
ILYPAIVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMV
LQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETP
HEKWFQDNYGDAIENALEKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVG
GTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLF
GLYKRWQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCT
TPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLS
CEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVL
PKLDGSLDEYLSLQEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLE
ATQLASLLQEISTQMDLGPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWK
TWMEELICNTTVERCQELYRKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHE
NGEEGSLSLASVIISALCTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVH
LANGVYTSLQELNSNFRQIIFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHA
QYGELIQPRNGSVDETPKMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKR
LQTIKEFFRLCGTFSKTLSGSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGV
DIIAQVEAKDFGAESKVSVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQQWQH
EDLLINRPQAMSVTPPPRSAILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQ
RASQVTFLCSNIIHFESLRTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMS
TQRAIQTEKEQQIETVCETIQNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLV
QAMGQVRSQEHVEMLQEITPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQ
KNLATSADTPPSTVPGTGKSVACSPKKAVRDPKTGKAVQERNSYAVSVWKRVKAKLEGRDVDPNRRMSVAEQVDYVIKEATNLDNLAQLY

--------------------------------------------------------------
>5042_5042_8_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000451270_SMG1_chr16_18883946_ENST00000446231_length(transcript)=14512nt_BP=700nt
GCCTCGCCTAGGGAGGATGTGGCGGGTATAAAAGCCCCACCCAGGCCAGCCGGCTCTGCTCAGCATTTGGGGACGCTCTCAGCTCTCGGC
GCACGGCCCAGCTTCCTTCAAAATGTCTACTGTTCACGAAATCCTGTGCAAGCTCAGCTTGGAGGGTGATCACTCTACACCCCCAAGTGC
ATATGGGTCTGTCAAAGCCTATACTAACTTTGATGCTGAGCGGGATGCTTTGAACATTGAAACAGCCATCAAGACCAAAGGTGTGGATGA
GGTCACCATTGTCAACATTTTGACCAACCGCAGCAATGCACAGAGACAGGATATTGCCTTCGCCTACCAGAGAAGGACCAAAAAGGAACT
TGCATCAGCACTGAAGTCAGCCTTATCTGGCCACCTGGAGACGGTGATTTTGGGCCTATTGAAGACACCTGCTCAGTATGACGCTTCTGA
GCTAAAAGCTTCCATGAAGGGGCTGGGAACCGACGAGGACTCTCTCATTGAGATCATCTGCTCCAGAACCAACCAGGAGCTGCAGGAAAT
TAACAGAGTCTACAAGGAAATGTACAAGACTGATCTGGAGAAGGACATTATTTCGGACACATCTGGTGACTTCCGCAAGCTGATGGTTGC
CCTGGCAAAGGGTAGAAGAGCAGAGGATGGCTCTGTCATTGATTATGAACTGATTGACCAAGATGCTCGGATGTGGGCGCTATCTCCAAC
TGTCTTTGCACTTCTGAGTAAGAATCTGATGATTGTGCACAGTGACCTGGCTGTTCACTTCCCTGCCATTCAGTATGCTGTGCTCTACAC
ATTGTATTCTCATTGTACCAGGCATGATCACTTTATCTCTAGTAGCCTCAGTTCTTCCTCTCCTTCTTTGTTTGATGGAGCTGTGATTAG
CACTGTAACTACGGCTACAAAGAAACATTTCTCAATTATATTAAATCTTCTGGGAATATTACTTAAGAAAGATAACCTTAACCAGGACAC
GAGGAAACTGTTAATGACTTGGGCTTTGGAAGCAGCTGTTTTAATGAAGAAGTCTGAAACATACGCACCTTTATTCTCTCTTCCGTCTTT
CCATAAATTTTGCAAAGGCCTTTTAGCCAACACTCTCGTTGAAGATGTGAATATCTGTCTGCAGGCATGCAGCAGTCTACATGCTCTGTC
CTCTTCCTTGCCAGATGATCTTTTACAGAGATGTGTCGATGTTTGCCGTGTTCAACTAGTGCACAGTGGAACTCGTATTCGACAAGCATT
TGGAAAACTGTTGAAATCAATTCCTTTAGATGTTGTCCTAAGCAATAACAATCACACAGAAATTCAAGAAATTTCTTTAGCATTAAGAAG
TCACATGAGTAAAGCACCAAGTAATACATTCCACCCCCAAGATTTCTCTGATGTTATTAGTTTTATTTTGTATGGGAACTCTCATAGAAC
AGGGAAGGACAATTGGTTGGAAAGACTGTTCTATAGCTGCCAGAGACTGGATAAGCGTGACCAGTCAACAATTCCACGCAATCTCCTGAA
GACAGATGCTGTCCTTTGGCAGTGGGCCATATGGGAAGCTGCACAATTCACTGTTCTTTCTAAGCTGAGAACCCCACTGGGCAGAGCTCA
AGACACCTTCCAGACAATTGAAGGTATCATTCGAAGTCTCGCAGCTCACACATTAAACCCTGATCAGGATGTTAGTCAGTGGACAACTGC
AGACAATGATGAAGGCCATGGTAACAACCAACTTAGACTTGTTCTTCTTCTGCAGTATCTGGAAAATCTGGAGAAATTAATGTATAATGC
ATACGAGGGATGTGCTAATGCATTAACTTCACCTCCCAAGGTCATTAGAACTTTTTTCTATACCAATCGCCAAACTTGTCAGGACTGGCT
AACGCGGATTCGACTCTCCATCATGAGGGTAGGATTGTTGGCAGGCCAGCCTGCAGTGACAGTGAGACATGGCTTTGACTTGCTTACAGA
GATGAAAACAACCAGCCTATCTCAGGGGAATGAATTGGAAGTAACCATTATGATGGTGGTAGAAGCATTATGTGAACTTCATTGTCCTGA
AGCTATACAGGGAATTGCTGTCTGGTCATCATCTATTGTTGGAAAAAATCTTCTGTGGATTAACTCAGTGGCTCAACAGGCTGAAGGGAG
GTTTGAAAAGGCCTCTGTGGAGTACCAGGAACACCTGTGTGCCATGACAGGTGTTGATTGCTGCATCTCCAGCTTTGACAAATCGGTGCT
CACCTTAGCCAATGCTGGGCGTAACAGTGCCAGCCCGAAACATTCTCTGAATGGTGAATCCAGAAAAACTGTGCTGTCCAAACCGACTGA
CTCTTCCCCTGAGGTTATAAATTATTTAGGAAATAAAGCATGTGAGTGCTACATCTCAATTGCCGATTGGGCTGCTGTGCAGGAATGGCA
GAACGCTATCCATGACTTGAAAAAGAGTACCAGTAGCACTTCCCTCAACCTGAAAGCTGACTTCAACTATATAAAATCATTAAGCAGCTT
TGAGTCTGGAAAATTTGTTGAATGTACCGAGCAGTTAGAATTGTTACCAGGAGAAAATATCAATCTACTTGCTGGAGGATCAAAAGAAAA
AATAGACATGAAAAAACTGCTTCCTAACATGTTAAGTCCGGATCCGAGGGAACTTCAGAAATCCATTGAAGTTCAATTGTTAAGAAGTTC
TGTTTGTTTGGCAACTGCTTTAAACCCGATAGAACAAGATCAGAAGTGGCAGTCTATAACTGAAAATGTGGTAAAGTACTTGAAGCAAAC
ATCCCGCATCGCTATTGGACCTCTGAGACTTTCTACTTTAACAGTTTCACAGTCTTTGCCAGTTCTAAGTACCTTGCAGCTGTATTGCTC
ATCTGCTTTGGAGAACACAGTTTCTAACAGACTTTCAACAGAGGACTGTCTTATTCCACTCTTCAGTGAAGCTTTACGTTCATGTAAACA
GCATGACGTGAGGCCATGGATGCAGGCATTAAGGTATACTATGTACCAGAATCAGTTGTTGGAGAAAATTAAAGAACAAACAGTCCCAAT
TAGAAGCCATCTCATGGAATTAGGTCTAACAGCAGCAAAATTTGCTAGAAAACGAGGGAATGTGTCCCTTGCAACAAGACTGCTGGCACA
GTGCAGTGAAGTTCAGCTGGGAAAGACCACCACTGCACAGGATTTAGTCCAACATTTTAAAAAACTATCAACCCAAGGTCAAGTGGATGA
AAAATGGGGGCCCGAACTTGATATTGAAAAAACCAAATTGCTTTATACAGCAGGCCAGTCAACACATGCAATGGAAATGTTGAGTTCTTG
TGCCATATCTTTCTGCAAGTCTGTGAAAGCTGAATATGCAGTTGCTAAATCAATTCTGACACTGGCTAAATGGATCCAGGCAGAATGGAA
AGAGATTTCAGGACAGCTGAAACAGGTTTACAGAGCTCAGCACCAACAGAACTTCACAGGTCTTTCTACTTTGTCTAAAAACATACTCAC
TCTAATAGAACTGCCATCTGTTAATACGATGGAAGAAGAGTATCCTCGGATCGAGAGTGAATCTACAGTGCATATTGGAGTTGGAGAACC
TGACTTCATTTTGGGACAGTTGTATCACCTGTCTTCAGTACAGGCACCTGAAGTAGCCAAATCTTGGGCAGCGTTGGCCAGCTGGGCTTA
TAGGTGGGGCAGAAAGGTGGTTGACAATGCCAGTCAGGGAGAAGGTGTTCGTCTGCTGCCTAGAGAAAAATCTGAAGTTCAGAATCTACT
TCCAGACACTATAACTGAGGAAGAGAAAGAGAGAATATATGGTATTCTTGGACAGGCTGTGTGTCGGCCGGCGGGGATTCAGGATGAAGA
TATAACACTTCAGATAACTGAGAGTGAAGACAACGAAGAAGATGACATGGTTGATGTTATCTGGCGTCAGTTGATATCAAGCTGCCCATG
GCTTTCAGAACTTGATGAAAGTGCAACTGAAGGAGTTATTAAAGTGTGGAGGAAAGTTGTAGATAGAATATTCAGCCTGTACAAACTCTC
TTGCAGTGCATACTTTACTTTCCTTAAACTCAACGCTGGTCAAATTCCTTTAGATGAGGATGACCCTAGGCTGCATTTAAGTCACAGAGT
GGAACAGAGCACTGATGACATGATTGTGATGGCCACATTGCGCCTGCTGCGGTTGCTCGTGAAGCATGCTGGTGAGCTTCGGCAGTATCT
GGAGCACGGCTTGGAGACAACACCCACTGCACCATGGAGAGGAATTATTCCGCAACTTTTCTCACGCTTAAACCACCCTGAAGTGTATGT
GCGCCAAAGTATTTGTAACCTTCTCTGCCGTGTGGCTCAAGATTCCCCACATCTCATATTGTATCCTGCAATAGTGGGTACCATATCGCT
TAGTAGTGAATCCCAGGCTTCAGGAAATAAATTTTCCACTGCAATTCCAACTTTACTTGGCAATATTCAAGGAGAAGAATTGCTGGTTTC
TGAATGTGAGGGAGGAAGTCCTCCTGCATCTCAGGATAGCAATAAGGATGAACCTAAAAGTGGATTAAATGAAGACCAAGCCATGATGCA
GGATTGTTACAGCAAAATTGTAGATAAGCTGTCCTCTGCAAACCCCACCATGGTATTACAGGTTCAGATGCTCGTGGCTGAACTGCGCAG
GGTCACTGTGCTCTGGGATGAGCTCTGGCTGGGAGTTTTGCTGCAACAACACATGTATGTCCTGAGACGAATTCAGCAGCTTGAAGATGA
GGTGAAGAGAGTCCAGAACAACAACACCTTACGCAAAGAAGAGAAAATTGCAATCATGAGGGAGAAGCACACAGCTTTGATGAAGCCCAT
CGTATTTGCTTTGGAGCATGTGAGGAGTATCACAGCGGCTCCTGCAGAAACACCTCATGAAAAATGGTTTCAGGATAACTATGGTGATGC
CATTGAAAATGCCCTAGAAAAACTGAAGACTCCATTGAACCCTGCAAAGCCTGGGAGCAGCTGGATTCCATTTAAAGAGATAATGCTAAG
TTTGCAACAGAGAGCACAGAAACGTGCAAGTTACATCTTGCGTCTTGAAGAAATCAGTCCATGGTTGGCTGCCATGACTAACACTGAAAT
TGCTCTTCCTGGGGAAGTCTCAGCCAGAGACACTGTCACAATCCATAGTGTGGGCGGAACCATCACAATCTTACCGACTAAAACCAAGCC
AAAGAAACTTCTCTTTCTTGGATCAGATGGGAAGAGCTATCCTTATCTTTTCAAAGGACTGGAGGATTTACATCTGGATGAGAGAATAAT
GCAGTTCCTATCTATTGTGAATACCATGTTTGCTACAATTAATCGCCAAGAAACACCCCGGTTCCATGCTCGACACTATTCTGTAACACC
ACTAGGAACAAGATCAGGACTAATCCAGTGGGTAGATGGAGCCACACCCTTATTTGGTCTTTACAAACGATGGCAACAACGGGAAGCTGC
CTTACAAGCACAAAAGGCCCAAGATTCCTACCAAACTCCTCAGAATCCTGGAATTGTACCCCGTCCTAGTGAACTTTATTACAGTAAAAT
TGGCCCTGCTTTGAAAACAGTTGGGCTTAGCCTGGATGTGTCCCGTCGGGATTGGCCTCTTCATGTAATGAAGGCAGTATTGGAAGAGTT
AATGGAGGCCACACCCCCGAATCTCCTTGCCAAAGAGCTCTGGTCATCTTGCACAACACCTGATGAATGGTGGAGAGTTACGCAGTCTTA
TGCAAGATCTACTGCAGTCATGTCTATGGTTGGATACATAATTGGCCTTGGAGACAGACATCTGGATAATGTTCTTATAGATATGACGAC
TGGAGAAGTTGTTCACATAGATTACAATGTTTGCTTTGAAAAAGGTAAAAGCCTTAGAGTTCCTGAGAAAGTACCTTTTCGAATGACACA
AAACATTGAAACAGCACTGGGTGTAACTGGAGTAGAAGGTGTATTTAGGCTTTCATGTGAGCAGGTTTTACACATTATGCGGCGTGGCAG
AGAGACCCTGCTGACGCTGCTGGAGGCCTTTGTGTACGACCCTCTGGTGGACTGGACAGCAGGAGGCGAGGCTGGGTTTGCTGGTGCTGT
CTATGGTGGAGGTGGCCAGCAGGCCGAGAGCAAGCAGAGCAAGAGAGAGATGGAGCGAGAGATCACCCGCAGCCTGTTTTCTTCTAGAGT
AGCTGAGATTAAGGTGAACTGGTTTAAGAATAGAGATGAGATGCTGGTTGTGCTTCCCAAGTTGGACGGTAGCTTAGATGAATACCTAAG
CTTGCAAGAGCAACTGACAGATGTGGAAAAACTGCAGGGCAAACTACTGGAGGAAATAGAGTTTCTAGAAGGAGCTGAAGGGGTGGATCA
TCCTTCTCATACTCTGCAACACAGGTATTCTGAGCACACCCAACTACAGACTCAGCAAAGAGCTGTTCAGGAAGCAATCCAGGTGAAGCT
GAATGAATTTGAACAATGGATAACACATTATCAGGCTGCATTCAATAATTTAGAAGCAACACAGCTTGCAAGCTTGCTTCAAGAGATAAG
CACACAAATGGACCTTGGTCCTCCAAGTTACGTGCCAGCAACAGCCTTTCTGCAGAATGCTGGTCAGGCCCACTTGATTAGCCAGTGCGA
GCAGCTGGAGGGGGAGGTTGGTGCTCTCCTGCAGCAGAGGCGCTCCGTGCTCCGTGGCTGTCTGGAGCAACTGCATCACTATGCAACCGT
GGCCCTGCAGTATCCGAAGGCCATATTTCAGAAACATCGAATTGAACAGTGGAAGACCTGGATGGAAGAGCTCATCTGTAACACCACAGT
AGAGCGTTGTCAAGAGCTCTATAGGAAATATGAAATGCAATATGCTCCCCAGCCACCCCCAACAGTGTGTCAGTTCATCACTGCCACTGA
AATGACCCTGCAGCGATACGCAGCAGACATCAACAGCAGACTTATTAGACAAGTGGAACGCTTGAAACAGGAAGCTGTCACTGTGCCAGT
TTGTGAAGATCAGTTGAAAGAAATTGAACGTTGCATTAAAGTTTTCCTTCATGAGAATGGAGAAGAAGGATCTTTGAGTCTAGCAAGTGT
TATTATTTCTGCCCTTTGTACCCTTACAAGGCGTAACCTGATGATGGAAGGTGCAGCGTCAAGTGCTGGAGAACAGCTGGTTGATCTGAC
TTCTCGGGATGGAGCCTGGTTCTTGGAGGAACTCTGCAGTATGAGCGGAAACGTCACCTGCTTGGTTCAGTTACTGAAGCAGTGCCACCT
GGTGCCACAGGACTTAGATATCCCGAACCCCATGGAAGCGTCTGAGACAGTTCACTTAGCCAATGGAGTGTATACCTCACTTCAGGAATT
GAATTCGAATTTCCGGCAAATCATATTTCCAGAAGCACTTCGATGTTTAATGAAAGGGGAATACACGTTAGAAAGTATGCTGCATGAACT
GGACGGTCTTATTGAGCAGACCACCGATGGCGTTCCCCTGCAGACTCTAGTGGAATCTCTTCAGGCCTACTTAAGAAACGCAGCTATGGG
ACTGGAAGAAGAAACACATGCTCATTACATCGATGTTGCCAGACTACTACATGCTCAGTACGGTGAATTAATCCAACCGAGAAATGGTTC
AGTTGATGAAACACCCAAAATGTCAGCTGGCCAGATGCTTTTGGTAGCATTCGATGGCATGTTTGCTCAAGTTGAAACTGCTTTCAGCTT
ATTAGTTGAAAAGTTGAACAAGATGGAAATTCCCATAGCTTGGCGAAAGATTGACATCATAAGGGAAGCCAGGAGTACTCAAGTTAATTT
TTTTGATGATGATAATCACCGGCAGGTGCTAGAAGAGATTTTCTTTCTAAAAAGACTACAGACTATTAAGGAGTTCTTCAGGCTCTGTGG
TACCTTTTCTAAAACATTGTCAGGATCAAGTTCACTTGAAGATCAGAATACTGTGAATGGGCCTGTACAGATTGTCAATGTGAAAACCCT
TTTTAGAAACTCTTGTTTCAGTGAAGACCAAATGGCCAAACCTATCAAGGCATTCACAGCTGACTTTGTGAGGCAGCTCTTGATAGGGCT
ACCCAACCAAGCCCTCGGACTCACACTGTGCAGTTTTATCAGTGCTCTGGGTGTAGACATCATTGCTCAAGTAGAGGCAAAGGACTTTGG
TGCCGAAAGCAAAGTTTCTGTTGATGATCTCTGTAAGAAAGCGGTGGAACATAACATCCAGATAGGGAAGTTCTCTCAGCTGGTTATGAA
CAGGGCAACTGTGTTAGCAAGTTCTTACGACACTGCCTGGAAGAAGCATGACTTGGTGCGAAGGCTAGAAACCAGTATTTCTTCTTGTAA
GACAAGCCTGCAGCGGGTTCAGCTGCATATTGCCATGTTTCAGTGGCAACATGAAGATCTACTTATCAATAGACCACAAGCCATGTCAGT
CACACCTCCCCCACGGTCTGCTATCCTAACCAGCATGAAAAAGAAGCTGCATACCCTGAGCCAGATTGAAACTTCTATTGCAACAGTTCA
GGAGAAGCTAGCTGCACTTGAATCAAGTATTGAACAGCGACTCAAGTGGGCAGGTGGTGCCAACCCTGCATTGGCCCCTGTACTACAAGA
TTTTGAAGCAACGATAGCTGAAAGAAGAAATCTTGTCCTTAAAGAGAGCCAAAGAGCAAGTCAGGTCACATTTCTCTGCAGCAATATCAT
TCATTTTGAAAGTTTACGAACAAGAACTGCAGAAGCCTTAAACCTGGATGCGGCGTTATTTGAACTAATCAAGCGATGTCAGCAGATGTG
TTCGTTTGCATCACAGTTTAACAGTTCAGTGTCTGAGTTAGAGCTTCGTTTATTACAGAGAGTGGACACTGGTCTTGAACATCCTATTGG
CAGCTCTGAATGGCTTTTGTCAGCACACAAACAGTTGACCCAGGATATGTCTACTCAGAGGGCAATTCAGACAGAGAAAGAGCAGCAGAT
AGAAACGGTCTGTGAAACAATTCAGAATCTGGTTGATAATATAAAGACTGTGCTCACTGGTCATAACCGACAGCTTGGAGATGTCAAACA
TCTCTTGAAAGCTATGGCTAAGGATGAAGAAGCTGCTCTGGCAGATGGTGAAGATGTTCCCTATGAGAACAGTGTTAGGCAGTTTTTGGG
TGAATATAAATCATGGCAAGACAACATTCAAACAGTTCTATTTACATTAGTCCAGGCTATGGGTCAGGTTCGAAGTCAAGAACACGTTGA
AATGCTCCAGGAAATCACTCCCACCTTGAAAGAACTGAAAACACAAAGTCAGAGTATCTATAATAATTTAGTGAGTTTTGCATCACCCTT
AGTCACCGATGCAACAAATGAATGTTCGAGTCCAACGTCATCTGCTACTTATCAGCCATCCTTCGCTGCAGCAGTCCGGAGTAACACTGG
CCAGAAGACTCAGCCTGATGTCATGTCACAGAATGCTAGAAAGCTGATCCAAAAAAATCTTGCTACATCAGCTGATACTCCACCAAGCAC
CGTTCCAGGAACTGGCAAGAGTGTTGCTTGTAGTCCTAAAAAGGCAGTCAGAGACCCTAAAACTGGGAAAGCGGTGCAAGAGAGAAACTC
CTATGCAGTGAGTGTGTGGAAGAGAGTGAAAGCCAAGTTAGAGGGCCGAGATGTTGATCCGAATAGGAGGATGTCAGTTGCTGAACAGGT
TGACTATGTCATTAAGGAAGCAACTAATCTAGATAACTTGGCTCAGCTGTATGAAGGTTGGACAGCCTGGGTGTGAATGGCAAGACAGTA
GATGAGTCTGGTTAAGCGAGGTCAGACATCCACCAGAATCAACTCAGCCTCAGGCATCCAAAGCCACACCACAGTCGGTGGTGATGCAAC
TGGGGGCTTACTCTGAGGAAACCTAGGAAATCTCGGTGCACTAGGAAGTGAATCCCGCAGGACAGCTGCACTCAGGGATACGCCCAACAC
CATGGCCTGCAACCCCAGGGTCAAGGGTGAAGGAAAGCAAGCTCACCGCCTGAACACGGAGATTGTCTTTCTGCCACAGAACAGCAGCAG
ACGTGTCGGGAGGTTAGCTGCGGAAAGAAATCGGGATGCCGCGGAGCACAGAGTGATTTGGAACTCCATTCCACCTGACCCTGTGTGTAC
AATCCAGGAAAAAAACAAACCCCACTCAGAAACAGAGAAAACTGGGGTCGCGAAGAAATCACAGCCAAGGAAGATTTGATGCATTCAGAT
TCTCGTGTAACACTTGTTGCTTGGCAACAGTACTGGTTGGGTTGACCAGTAAGTAGAAAAAGGCTAAAGGCTATGCGATATGAATTTCAG
AAATGGACTGAAAATGGAGAGCTATGTAACAGATACACTACAGTAGAAGAACTTACTTCTGAAATGAAGGGAAAAAAACCACCCCATCGT
TCCCTACTCCTCCCCACCACTTACCCGTTCCCCCTTTACCTAATCTAGTAGATTAGCCATCTTTCAAATTCACTTTTATTTCAGTCCTTA
TATTTCATATACTTCCGTCTCGATGCTGTTAACAACTTCTGATAACATGGAAAATTCAAGGATTGTTTAAAGGTCTGATGATCACACACA
AAATGTAATTCCGGTTATTTAAGTCATTTCTGTGATTCTATCATGTACAGTTTCCAGAATTGTCACTGTGCATTCAAAAGTAATGAATCT
AACAGACATTTGATTTAATGTACACTCCCTTTTGCTTATAGTGTGCATTTTTTTTGGAGGTCATTCAAATTTTCCCTCTTCTGTGATAGC
TGTAGTTTCTTTCATAGAAAGTAGCTAATCCAGTGTAATCTTTTACCTTTTTAAAAACCAAGATAGAGTATCTATTAGAGTTTTACATTG
TTGATGATAGATTAACAATAAAGTGATGTTCTGGTGGAGGTAGACTGAAATTTTTTTAATTCATGTTTTTCATTTGATACTTTTAATTTA
CACTTAGTAAATTAAAAGTTGTTTAATTTACTTGGCATTTTAGGACATGTACATGAAACAGTGAAAATGAGATCCACCAACATCTTTTAT
TAAGTTCAGTTATTAGTCTGTGAAGTGCTTTACTTTTTGCACAATTTTAATAGCTTGCTATTCAGTAATACATTATAGTGAATTCATGAT
CAAGGTTTCCTTAAATTTAGCATTGCATTTCAGTACTGACTGTGTAAGCTAAATTGCTGATCCAAAATAAAAACCCAGACTAGAATAGGG
TTCTTAAAATCAAGTATCAATACAAAATAGAACACAATTAAAATCTTAATTGTTGGCTGGGCACAGTGGCTCACGCCTGTAATCCCAGCA
CTTTGGGAGGCCGAGGCGGGCGGATCATGAGGTTAGGAGAGCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTTTACTAAAAATAC
AAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCG
GAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCAACAGAGCTAGACTCTGTGTCAAAAATAAATGACTAGATAAAAA
AAAAAATTGTTTGAGTACATTTTCCCTGCATTTTAGAGATTAGGACAGTGGTCACTTTCTAGTTGCCGTCTTCACAGACAAACTTGAAAG
GTATTAAGGAAAAAATTCCACATAGCTCTGGGCCTTTTTTGTATTCTGATTGCCACGTTAATCTGTAATCGTTAAGTACCCATGAAAGAA
TGTGTTTCAGTATCAGTGCTTTTTTGGTACTTTAACAAGTATTGTAGGCACGGTGGATTTTTTTGAAATACCCATGTGTCCAATAGCAAG
TTAAGGAACCTAGCGCATCAAATTTTGTTTTCTTCATTCATTTGGAACCTTATTTTCGCAAAAAACCTAGCTGGAATAATAATGCCATAT
TGTATTTTGCACACTGCTTTATTTTCTAGAGGCTCTGGGAGCAAATTACATTCATCACATTACCTCTGCTCTCTCAAGATTAAAGTCTTT
CAGCAACATTCTTTATTGTCATCATAAGGAAAAACTTTTATCGCAATGATAGTCAGTTCACATTAGTTTAGCACTATAGATAGTATTCAG
AAATTGCTTTCTCTTTGGTAAAGAAGATAAATAGGTGAATTTTATTGCCTGTGTTTTCAGGCTTCAGAGGTACCTGGCACCTTACTCAAG
CAAAAACAAAAAACAGCTTTACTTCAAAAGCATGTGCCTCTGGTAAATTATCCATCACTTTTGTTTTAAAGTGGTCCCTCCAAGAATAAT
GTGGCATACACAGTGGGTTTGGTTGTAAGGCAGATGTAATAGATGACTTCAAAAGCCTGCTCCTTACTGCACTCTGGACAAGGCCCTGGT
CTGTATAGTTTGGCTTCCTCTGTTAAGTCATTCTACAAGGTGACTTGCCATTTGAACTTTCGTAAGAGACCTCAGCAGTTAGACTGAGAA
AAGTTAGAGTGCTGTAGTTATGAAGTCATACATTTTTGATAAAATACCTGTGGAAAACCAGGGATCCTCTCCTGTTTCTCTCTCTTGCCT
CCCCCTTTCCCTCCATTCCTCTGTCGCCTCCCCCTCTCCTCCACTTTCTTTAAGAATCAGGGGGTACAGAATAACCTACAAACAACCTCT
TCAAAGTACCCTTGGAAATTGAAGTTCAATCTTAAGTTTTTTGCTGTCTTTAATTTACTAGAATTGCCTAATTTTTAGTTGATTTCTCTA
CAGAGCTTAGCTTGTGTAGTTATTTCTCTTTTACTGTTGCTTTGGTGTGTCTTGAAGTTTGATTGATTATTTTTGGTCATTGAGTTCTTA
GTGTAGTTTGCTAGATGATTATTAAGATTCTTTTGTGTCTGACACTTGTGGTGAGTTGCTTTTGAAATCTGTTGAGATTTCCATGTGAGA
ACTGATAATCAGGCTCTTGATCTGCTTCCCTAAATTACTTTTTTAGAGCCCAAACCCCAGGTTTAGGGTGAGGGTTTGTAATACAAAGAA
ACACTTCCATCACTTCTGCCCTTAACCCTTGCCTCTATTACCTAAGCTTAGTAAGTAGTTTTCTTAATATTGTCCAATGTTTGGTGTTAT
CTGCATTGTTTTTTGTTTTTTTAATTGTGGTTGTTCTGACGTGTGAAATTTAAGGAAAGAGCCATTTTTTAAAAATGCCGAGCAGGGCAA
TGCAAGTACAGCCAAATATTAGACTTGATGTGCAATCTTCGGTCCTTTTTAATCTGGGGTATTATAGGCAGTACTTTAAATTGCAAAGTC
TTCCGGGCCTATTTTCCTCTACATTTTTGTAATTAACTCTGGGGGCTTACTTGTTTTGGCAGTACTGAAATCAAAGGAGCTGGTTCTTCT
TTTCTCCCAATTATTTTCATATGAAAGCACCTACAATTAGCCTGTTAGTCCTATTCAGATACATCAAATATCAGTGAATGCTTTACTATT
CGCACATTTAAGCATCTTTGTTTTACATAAAATTAGAGTATGAAAACCAGTGTTCAATTTTTTATCTTGTTGAGCTTGTAAAATGCCAGC
AATTTAAAACTAGGACTTTTCCCCCCATAAGCCAAGGAGGTAGAATTACTAATACAAGGGTTAAAGAAGGTAGATTTTGTTTTCAATATT
TGGGTAATATTAGAAAGATTCTTCCCACAGGGAAGAACTAGCAAGTGTCCCAATTTTTTCCAAACGTTGGGGAGGGGAAAATTCACTGTA
TCATGAAACCCTAAGGGTTTGTTGCACTTCCTGCTTTTTAGGCCTGGATAACAGTATCACCATCCTTATTTACAGAAGGGTAAAACTGAC
TCTTAATGAGAAAAGCTTTATAAGTTCAAGGGCTGTAAAATATGAACTACTTAGGGTCGTTTGCCTTCCATGGGAACTTGGCTAGACTTA
GAAAAAGCTGTTTGTTGTGCTAATGTAAAAGTGTCATACAATTTAGAAGATTTTTGAAGATGGTAAACTTAGAAGAATTCTATGTTCTGA
AATGCACACTTTTAGAATGTTTTTCTTTGAAAACAGGCTAATAGTTTTTTCTTTTTTTGACAAAGTTTCAGCTCCTCTTTAAAGTTATTG
TGTCATTTTTCTGGTTTAAATTTCCCTTATATTTCCACCTGTAATGTCAGTGGCAACAACATCATACTTCACTTACTTGTTAATTTACTT
TTTACCCTTATTCTAAGAGCAAGTTGAGTTGAACTGAATCTTCCTTGTCTTAGTAACAATGTATAAATAGTGGCTTTTCTGTACAAAAGG
TTGTAATGCCTCCTGATGGATATAATTTTGTGATTGTATTTAAAAGTTGAATAAATCACACCAGCTTCCTGAAAATGTTCATAATGCATC
TTTTGGAAAACAAATACATGCCTACTTTGTGCATATTTGCATTAACATGGCAAAGATTGTATGAAATACCTGTTTTTCAGAAAATAAAGG

>5042_5042_8_ANXA2-SMG1_ANXA2_chr15_60646353_ENST00000451270_SMG1_chr16_18883946_ENST00000446231_length(amino acids)=3246AA_BP=215
MLSIWGRSQLSAHGPASFKMSTVHEILCKLSLEGDHSTPPSAYGSVKAYTNFDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDI
AFAYQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICSRTNQELQEINRVYKEMYKTDLEKDIIS
DTSGDFRKLMVALAKGRRAEDGSVIDYELIDQDARMWALSPTVFALLSKNLMIVHSDLAVHFPAIQYAVLYTLYSHCTRHDHFISSSLSS
SSPSLFDGAVISTVTTATKKHFSIILNLLGILLKKDNLNQDTRKLLMTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNI
CLQACSSLHALSSSLPDDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSKAPSNTFHPQDFSDV
ISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAVLWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTL
NPDQDVSQWTTADNDEGHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIRLSIMRVGLLAGQPA
VTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGV
DCCISSFDKSVLTLANAGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLK
ADFNYIKSLSSFESGKFVECTEQLELLPGENINLLAGGSKEKIDMKKLLPNMLSPDPRELQKSIEVQLLRSSVCLATALNPIEQDQKWQS
ITENVVKYLKQTSRIAIGPLRLSTLTVSQSLPVLSTLQLYCSSALENTVSNRLSTEDCLIPLFSEALRSCKQHDVRPWMQALRYTMYQNQ
LLEKIKEQTVPIRSHLMELGLTAAKFARKRGNVSLATRLLAQCSEVQLGKTTTAQDLVQHFKKLSTQGQVDEKWGPELDIEKTKLLYTAG
QSTHAMEMLSSCAISFCKSVKAEYAVAKSILTLAKWIQAEWKEISGQLKQVYRAQHQQNFTGLSTLSKNILTLIELPSVNTMEEEYPRIE
SESTVHIGVGEPDFILGQLYHLSSVQAPEVAKSWAALASWAYRWGRKVVDNASQGEGVRLLPREKSEVQNLLPDTITEEEKERIYGILGQ
AVCRPAGIQDEDITLQITESEDNEEDDMVDVIWRQLISSCPWLSELDESATEGVIKVWRKVVDRIFSLYKLSCSAYFTFLKLNAGQIPLD
EDDPRLHLSHRVEQSTDDMIVMATLRLLRLLVKHAGELRQYLEHGLETTPTAPWRGIIPQLFSRLNHPEVYVRQSICNLLCRVAQDSPHL
ILYPAIVGTISLSSESQASGNKFSTAIPTLLGNIQGEELLVSECEGGSPPASQDSNKDEPKSGLNEDQAMMQDCYSKIVDKLSSANPTMV
LQVQMLVAELRRVTVLWDELWLGVLLQQHMYVLRRIQQLEDEVKRVQNNNTLRKEEKIAIMREKHTALMKPIVFALEHVRSITAAPAETP
HEKWFQDNYGDAIENALEKLKTPLNPAKPGSSWIPFKEIMLSLQQRAQKRASYILRLEEISPWLAAMTNTEIALPGEVSARDTVTIHSVG
GTITILPTKTKPKKLLFLGSDGKSYPYLFKGLEDLHLDERIMQFLSIVNTMFATINRQETPRFHARHYSVTPLGTRSGLIQWVDGATPLF
GLYKRWQQREAALQAQKAQDSYQTPQNPGIVPRPSELYYSKIGPALKTVGLSLDVSRRDWPLHVMKAVLEELMEATPPNLLAKELWSSCT
TPDEWWRVTQSYARSTAVMSMVGYIIGLGDRHLDNVLIDMTTGEVVHIDYNVCFEKGKSLRVPEKVPFRMTQNIETALGVTGVEGVFRLS
CEQVLHIMRRGRETLLTLLEAFVYDPLVDWTAGGEAGFAGAVYGGGGQQAESKQSKREMEREITRSLFSSRVAEIKVNWFKNRDEMLVVL
PKLDGSLDEYLSLQEQLTDVEKLQGKLLEEIEFLEGAEGVDHPSHTLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLE
ATQLASLLQEISTQMDLGPPSYVPATAFLQNAGQAHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWK
TWMEELICNTTVERCQELYRKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEAVTVPVCEDQLKEIERCIKVFLHE
NGEEGSLSLASVIISALCTLTRRNLMMEGAASSAGEQLVDLTSRDGAWFLEELCSMSGNVTCLVQLLKQCHLVPQDLDIPNPMEASETVH
LANGVYTSLQELNSNFRQIIFPEALRCLMKGEYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHA
QYGELIQPRNGSVDETPKMSAGQMLLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARSTQVNFFDDDNHRQVLEEIFFLKR
LQTIKEFFRLCGTFSKTLSGSSSLEDQNTVNGPVQIVNVKTLFRNSCFSEDQMAKPIKAFTADFVRQLLIGLPNQALGLTLCSFISALGV
DIIAQVEAKDFGAESKVSVDDLCKKAVEHNIQIGKFSQLVMNRATVLASSYDTAWKKHDLVRRLETSISSCKTSLQRVQLHIAMFQWQHE
DLLINRPQAMSVTPPPRSAILTSMKKKLHTLSQIETSIATVQEKLAALESSIEQRLKWAGGANPALAPVLQDFEATIAERRNLVLKESQR
ASQVTFLCSNIIHFESLRTRTAEALNLDAALFELIKRCQQMCSFASQFNSSVSELELRLLQRVDTGLEHPIGSSEWLLSAHKQLTQDMST
QRAIQTEKEQQIETVCETIQNLVDNIKTVLTGHNRQLGDVKHLLKAMAKDEEAALADGEDVPYENSVRQFLGEYKSWQDNIQTVLFTLVQ
AMGQVRSQEHVEMLQEITPTLKELKTQSQSIYNNLVSFASPLVTDATNECSSPTSSATYQPSFAAAVRSNTGQKTQPDVMSQNARKLIQK
NLATSADTPPSTVPGTGKSVACSPKKAVRDPKTGKAVQERNSYAVSVWKRVKAKLEGRDVDPNRRMSVAEQVDYVIKEATNLDNLAQLYE

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Fusion Gene PPI Analysis for ANXA2-SMG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneSMG1chr15:60646353chr16:18883946ENST0000044623112631_1977630.03662.0SMG8 and SMG9


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANXA2-SMG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANXA2-SMG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource