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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABLIM1-FANK1 (FusionGDB2 ID:509)

Fusion Gene Summary for ABLIM1-FANK1

check button Fusion gene summary
Fusion gene informationFusion gene name: ABLIM1-FANK1
Fusion gene ID: 509
HgeneTgene
Gene symbol

ABLIM1

FANK1

Gene ID

3983

92565

Gene nameactin binding LIM protein 1fibronectin type III and ankyrin repeat domains 1
SynonymsABLIM|LIMAB1|LIMATIN|abLIM-1HSD13
Cytomap

10q25.3

10q26.2

Type of geneprotein-codingprotein-coding
Descriptionactin-binding LIM protein 1actin-binding LIM protein family member 1actin-binding double-zinc-finger proteinfibronectin type 3 and ankyrin repeat domains protein 1fibronectin type 3 and ankyrin repeat domains 1
Modification date2020031320200320
UniProtAcc

O14639

Q8TC84

Ensembl transtripts involved in fusion geneENST00000277895, ENST00000369252, 
ENST00000369253, ENST00000369266, 
ENST00000392952, ENST00000533213, 
ENST00000477638, 		ENST00000477963, 
ENST00000368689, ENST00000449042, 
ENST00000368693, ENST00000368695, 
Fusion gene scores* DoF score10 X 11 X 6=6608 X 9 X 4=288
# samples 119
** MAII scorelog2(11/660*10)=-2.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/288*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABLIM1 [Title/Abstract] AND FANK1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABLIM1(116198934)-FANK1(127696975), # samples:1
Anticipated loss of major functional domain due to fusion event.ABLIM1-FANK1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ABLIM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FANK1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-56-7579-11AABLIM1chr10

116198934

-FANK1chr10

127696975

+


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Fusion Gene ORF analysis for ABLIM1-FANK1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000277895ENST00000477963ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-3UTRENST00000369252ENST00000477963ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-3UTRENST00000369253ENST00000477963ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-3UTRENST00000369266ENST00000477963ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-3UTRENST00000392952ENST00000477963ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-3UTRENST00000533213ENST00000477963ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000277895ENST00000368689ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000277895ENST00000449042ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000369252ENST00000368689ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000369252ENST00000449042ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000369253ENST00000368689ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000369253ENST00000449042ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000369266ENST00000368689ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000369266ENST00000449042ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000392952ENST00000368689ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000392952ENST00000449042ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000533213ENST00000368689ABLIM1chr10

116198934

-FANK1chr10

127696975

+
5CDS-intronENST00000533213ENST00000449042ABLIM1chr10

116198934

-FANK1chr10

127696975

+
Frame-shiftENST00000369253ENST00000368693ABLIM1chr10

116198934

-FANK1chr10

127696975

+
Frame-shiftENST00000369253ENST00000368695ABLIM1chr10

116198934

-FANK1chr10

127696975

+
Frame-shiftENST00000369266ENST00000368693ABLIM1chr10

116198934

-FANK1chr10

127696975

+
Frame-shiftENST00000369266ENST00000368695ABLIM1chr10

116198934

-FANK1chr10

127696975

+
Frame-shiftENST00000392952ENST00000368693ABLIM1chr10

116198934

-FANK1chr10

127696975

+
Frame-shiftENST00000392952ENST00000368695ABLIM1chr10

116198934

-FANK1chr10

127696975

+
In-frameENST00000277895ENST00000368693ABLIM1chr10

116198934

-FANK1chr10

127696975

+
In-frameENST00000277895ENST00000368695ABLIM1chr10

116198934

-FANK1chr10

127696975

+
In-frameENST00000369252ENST00000368693ABLIM1chr10

116198934

-FANK1chr10

127696975

+
In-frameENST00000369252ENST00000368695ABLIM1chr10

116198934

-FANK1chr10

127696975

+
In-frameENST00000533213ENST00000368693ABLIM1chr10

116198934

-FANK1chr10

127696975

+
In-frameENST00000533213ENST00000368695ABLIM1chr10

116198934

-FANK1chr10

127696975

+
intron-3CDSENST00000477638ENST00000368693ABLIM1chr10

116198934

-FANK1chr10

127696975

+
intron-3CDSENST00000477638ENST00000368695ABLIM1chr10

116198934

-FANK1chr10

127696975

+
intron-3UTRENST00000477638ENST00000477963ABLIM1chr10

116198934

-FANK1chr10

127696975

+
intron-intronENST00000477638ENST00000368689ABLIM1chr10

116198934

-FANK1chr10

127696975

+
intron-intronENST00000477638ENST00000449042ABLIM1chr10

116198934

-FANK1chr10

127696975

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000369252ABLIM1chr10116198934-ENST00000368693FANK1chr10127696975+274922642962596766
ENST00000369252ABLIM1chr10116198934-ENST00000368695FANK1chr10127696975+275122642962596766
ENST00000533213ABLIM1chr10116198934-ENST00000368693FANK1chr10127696975+274922642962596766
ENST00000533213ABLIM1chr10116198934-ENST00000368695FANK1chr10127696975+275122642962596766
ENST00000277895ABLIM1chr10116198934-ENST00000368693FANK1chr10127696975+27252240802572830
ENST00000277895ABLIM1chr10116198934-ENST00000368695FANK1chr10127696975+27272240802572830

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000369252ENST00000368693ABLIM1chr10116198934-FANK1chr10127696975+0.0014704980.99852943
ENST00000369252ENST00000368695ABLIM1chr10116198934-FANK1chr10127696975+0.0014464590.9985536
ENST00000533213ENST00000368693ABLIM1chr10116198934-FANK1chr10127696975+0.0015011350.9984989
ENST00000533213ENST00000368695ABLIM1chr10116198934-FANK1chr10127696975+0.0014769330.99852306
ENST00000277895ENST00000368693ABLIM1chr10116198934-FANK1chr10127696975+0.0008548130.99914515
ENST00000277895ENST00000368695ABLIM1chr10116198934-FANK1chr10127696975+0.0008368060.99916315

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Fusion Genomic Features for ABLIM1-FANK1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ABLIM1chr10116198934-FANK1chr10127696975+2.32E-050.99997675
ABLIM1chr10116198934-FANK1chr10127696975+2.32E-050.99997675

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ABLIM1-FANK1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:116198934/chr10:127696975)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ABLIM1

O14639

FANK1

Q8TC84

FUNCTION: May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance. {ECO:0000250, ECO:0000269|PubMed:9245787}.FUNCTION: Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis. {ECO:0000269|PubMed:20978819, ECO:0000269|PubMed:27060496}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABLIM1chr10:116198934chr10:127696975ENST00000277895-2123590_614714779.0Coiled coilOntology_term=ECO:0000255
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369252-2123590_614654719.0Coiled coilOntology_term=ECO:0000255
HgeneABLIM1chr10:116198934chr10:127696975ENST00000277895-2123156_216714779.0DomainLIM zinc-binding 2
HgeneABLIM1chr10:116198934chr10:127696975ENST00000277895-2123224_283714779.0DomainLIM zinc-binding 3
HgeneABLIM1chr10:116198934chr10:127696975ENST00000277895-2123283_343714779.0DomainLIM zinc-binding 4
HgeneABLIM1chr10:116198934chr10:127696975ENST00000277895-212397_156714779.0DomainLIM zinc-binding 1
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369252-2123156_216654719.0DomainLIM zinc-binding 2
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369252-2123224_283654719.0DomainLIM zinc-binding 3
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369252-2123283_343654719.0DomainLIM zinc-binding 4
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369252-212397_156654719.0DomainLIM zinc-binding 1
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369253-1416156_216337402.0DomainLIM zinc-binding 2
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369253-1416224_283337402.0DomainLIM zinc-binding 3
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369253-141697_156337402.0DomainLIM zinc-binding 1
HgeneABLIM1chr10:116198934chr10:127696975ENST00000392952-1618156_216391456.0DomainLIM zinc-binding 2
HgeneABLIM1chr10:116198934chr10:127696975ENST00000392952-1618224_283391456.0DomainLIM zinc-binding 3
HgeneABLIM1chr10:116198934chr10:127696975ENST00000392952-1618283_343391456.0DomainLIM zinc-binding 4
HgeneABLIM1chr10:116198934chr10:127696975ENST00000392952-161897_156391456.0DomainLIM zinc-binding 1
TgeneFANK1chr10:116198934chr10:127696975ENST00000368693611243_273235346.0RepeatNote=ANK 5
TgeneFANK1chr10:116198934chr10:127696975ENST00000368693611277_306235346.0RepeatNote=ANK 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369253-1416590_614337402.0Coiled coilOntology_term=ECO:0000255
HgeneABLIM1chr10:116198934chr10:127696975ENST00000392952-1618590_614391456.0Coiled coilOntology_term=ECO:0000255
HgeneABLIM1chr10:116198934chr10:127696975ENST00000277895-2123710_778714779.0DomainHP
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369252-2123710_778654719.0DomainHP
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369253-1416283_343337402.0DomainLIM zinc-binding 4
HgeneABLIM1chr10:116198934chr10:127696975ENST00000369253-1416710_778337402.0DomainHP
HgeneABLIM1chr10:116198934chr10:127696975ENST00000392952-1618710_778391456.0DomainHP
TgeneFANK1chr10:116198934chr10:127696975ENST000003686936118_108235346.0DomainFibronectin type-III
TgeneFANK1chr10:116198934chr10:127696975ENST00000368693611109_139235346.0RepeatNote=ANK 1
TgeneFANK1chr10:116198934chr10:127696975ENST00000368693611143_172235346.0RepeatNote=ANK 2
TgeneFANK1chr10:116198934chr10:127696975ENST00000368693611176_205235346.0RepeatNote=ANK 3
TgeneFANK1chr10:116198934chr10:127696975ENST00000368693611209_238235346.0RepeatNote=ANK 4


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Fusion Gene Sequence for ABLIM1-FANK1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>509_509_1_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000277895_FANK1_chr10_127696975_ENST00000368693_length(transcript)=2725nt_BP=2240nt
AGACAGTAAGGAGCCAGGGGAACAGAGAGAATTGTGGGGCAGCACCGCTCCTTGGGTCCCCACTCCCCATTTCTCATTGCTTGGAAATCC
ATGCCAAGATGCCTGCCTTCCTTGGTCTAAAGTGTCTGGGGAAATTGTGCAGCTCTGAGAAAAGCAAAGTCACCTCATCTGAGAGAACCA
GTGCCAGGGGCTCGAACAGAAAGAGACTGATTGTTGAGGACCGGAGGGTCTCTGGGACCTCCTTCACCGCTCATAGGCGTGCCACTATCA
CTCATTTGCTGTATCTCTGTCCCAAGGACTACTGCCCACGTGGGCGTGTATGTAACAGCGTTGATCCTTTTGTGGCCCACCCTCAGGACC
CTCACCACCCATCAGAGAAGCCTGTCATTCACTGCCATAAATGTGGGGAGCCTTGCAAGGGTGAAGTGCTTCGGGTCCAGACCAAACATT
TCCACATCAAGTGTTTCACCTGCAAAGTGTGTGGCTGTGACCTGGCACAAGGGGGCTTCTTCATAAAGAACGGAGAGTATCTCTGCACCC
TGGACTACCAGCGGATGTACGGGACACGCTGCCATGGCTGTGGGGAGTTCGTGGAGGGCGAAGTGGTGACTGCTCTGGGCAAGACCTACC
ATCCCAATTGCTTTGCTTGTACTATCTGCAAGCGCCCGTTTCCACCCGGAGACCGAGTCACATTCAATGGGAGAGACTGCCTTTGTCAAC
TCTGTGCACAGCCGATGTCGTCCAGTCCGAAAGAAACCACCTTCTCCAGCAATTGTGCCGGCTGCGGAAGAGATATCAAGAATGGGCAGG
CGCTGCTGGCGCTGGATAAGCAGTGGCACTTGGGGTGCTTTAAATGCAAGTCCTGCGGGAAGGTCCTCACCGGGGAGTACATCAGCAAGG
ATGGTGCTCCGTACTGTGAAAAGGACTACCAGGGACTCTTTGGGGTGAAATGTGAGGCGTGTCACCAGTTTATCACAGGGAAAGTCCTGG
AGGCAGGTGACAAACATTACCACCCCAGCTGTGCACGATGCAGCAGATGCAACCAGATGTTCACAGAAGGAGAGGAAATGTATCTTCAAG
GCTCCACCGTTTGGCATCCCGACTGTAAGCAATCTACGAAGACCGAGGAAAAGCTGCGGCCTACCAGGACATCCTCGGAAAGTATTTATT
CTAGGCCAGGCTCCAGTATTCCTGGCTCACCAGGTCATACTATCTATGCAAAAGTAGACAATGAGATCCTGGATTACAAGGATTTAGCAG
CCATTCCGAAGGTCAAGGCAATTTATGACATTGAACGTCCAGATCTTATTACCTATGAGCCTTTCTACACTTCGGGCTATGATGACAAAC
AGGAGAGACAGAGCCTTGGAGAGTCTCCGAGGACTTTGTCTCCTACTCCATCAGCAGAAGGGTACCAGGATGTTCGGGATCGGATGATCC
ATCGGTCCACGAGCCAGGGCTCCATCAACTCCCCTGTGTACAGCCGCCACAGCTACACTCCAACCACGTCCCGCTCTCCCCAGCATTTCC
ACAGACCTGGCAATGAGCCGTCCAGCGGCCGGAACTCCCCTCTCCCTTACCGGCCAGACAGCCGCCCTCTAACTCCAACTTACGCTCAGG
CCCCTAAACATTTCCATGTTCCAGATCAAGGAATCAACATTTACCGAAAGCCACCCATCTACAAACAGCATGCTGCCTTGGCAGCCCAGA
GCAAGTCCTCAGAAGATATCATCAAGTTTTCCAAGTTCCCAGCAGCCCAGGCACCAGACCCCAGCGAGACACCAAAGATTGAGACGGACC
ACTGGCCTGGTCCCCCCTCATTTGCTGTCGTAGGACCTGACATGAAACGCAGATCTAGTGGCAGAGAGGAAGATGATGAGGAACTTCTGA
GACGTCGGCAGCTTCAAGAAGAGCAATTAATGAAGCTTAACTCAGGCCTGGGACAGTTGATCTTGAAAGAAGAGATGGAGAAAGAGAGCC
GGGAAAGGTCATCTCTGTTAGCCAGTCGCTACGATTCTCCCATCAACTCAGCTTCACATATTCCATCATCTAAAACTGCATCTCTCCCTG
GCTATGGAAGAAATGGGCTTCACCGGCCTGTTTCTACCGACTTCGCTCAGTATAACAGCTATGGGGATGTCAGCGGGGGAGTGCGAGATT
ACCAGACACTCCCAGATGGCCACATGCCTGCAATGAGAATGGACCGAGGAGTGTCTATGCCCAACATGTTGGAACCAAAGGTAGACGTCG
TGGACACTGGTTCAGGATGGACCCCACTCATGAGAGTCTCTGCGGTGTCGGGAAATCAGAGGGTGGCCTCTCTTCTAATTGATGCTGGGG
CCAATGTGAATGTGAAGGACAGAAATGGAAAGACGCCCCTTATGGTGGCTGTGTTAAATAATCATGAAGAGTTAGTTCAGTTACTTCTTG
ACAAAGGGGCAGATGCAAGTGTAAAAAATGAGTTCGGCAAAGGTGTCCTAGAAATGGCCAGAGTTTTTGACAGACAGAGTGTAGTCTCCT
TATTAGAAGAAAGGAAAAAAAAGCAGAGGCCAAAGAAGTCTTGTGTCTGCTGATGAGAGCACCACTCATCTGCGAAACGCACGTAAAACA
AAGTGAACCGTGACTGTTAAACTAGGGATGGGAAATTCTGCATCTTGGGGGGCTGTACATTTATTTATTTAGTTGAAGATTCACTGATCC

>509_509_1_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000277895_FANK1_chr10_127696975_ENST00000368693_length(amino acids)=830AA_BP=720
MEIHAKMPAFLGLKCLGKLCSSEKSKVTSSERTSARGSNRKRLIVEDRRVSGTSFTAHRRATITHLLYLCPKDYCPRGRVCNSVDPFVAH
PQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALG
KTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEY
ISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSE
SIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRD
RMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAAL
AAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEME
KESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPK
VDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQS

--------------------------------------------------------------
>509_509_2_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000277895_FANK1_chr10_127696975_ENST00000368695_length(transcript)=2727nt_BP=2240nt
AGACAGTAAGGAGCCAGGGGAACAGAGAGAATTGTGGGGCAGCACCGCTCCTTGGGTCCCCACTCCCCATTTCTCATTGCTTGGAAATCC
ATGCCAAGATGCCTGCCTTCCTTGGTCTAAAGTGTCTGGGGAAATTGTGCAGCTCTGAGAAAAGCAAAGTCACCTCATCTGAGAGAACCA
GTGCCAGGGGCTCGAACAGAAAGAGACTGATTGTTGAGGACCGGAGGGTCTCTGGGACCTCCTTCACCGCTCATAGGCGTGCCACTATCA
CTCATTTGCTGTATCTCTGTCCCAAGGACTACTGCCCACGTGGGCGTGTATGTAACAGCGTTGATCCTTTTGTGGCCCACCCTCAGGACC
CTCACCACCCATCAGAGAAGCCTGTCATTCACTGCCATAAATGTGGGGAGCCTTGCAAGGGTGAAGTGCTTCGGGTCCAGACCAAACATT
TCCACATCAAGTGTTTCACCTGCAAAGTGTGTGGCTGTGACCTGGCACAAGGGGGCTTCTTCATAAAGAACGGAGAGTATCTCTGCACCC
TGGACTACCAGCGGATGTACGGGACACGCTGCCATGGCTGTGGGGAGTTCGTGGAGGGCGAAGTGGTGACTGCTCTGGGCAAGACCTACC
ATCCCAATTGCTTTGCTTGTACTATCTGCAAGCGCCCGTTTCCACCCGGAGACCGAGTCACATTCAATGGGAGAGACTGCCTTTGTCAAC
TCTGTGCACAGCCGATGTCGTCCAGTCCGAAAGAAACCACCTTCTCCAGCAATTGTGCCGGCTGCGGAAGAGATATCAAGAATGGGCAGG
CGCTGCTGGCGCTGGATAAGCAGTGGCACTTGGGGTGCTTTAAATGCAAGTCCTGCGGGAAGGTCCTCACCGGGGAGTACATCAGCAAGG
ATGGTGCTCCGTACTGTGAAAAGGACTACCAGGGACTCTTTGGGGTGAAATGTGAGGCGTGTCACCAGTTTATCACAGGGAAAGTCCTGG
AGGCAGGTGACAAACATTACCACCCCAGCTGTGCACGATGCAGCAGATGCAACCAGATGTTCACAGAAGGAGAGGAAATGTATCTTCAAG
GCTCCACCGTTTGGCATCCCGACTGTAAGCAATCTACGAAGACCGAGGAAAAGCTGCGGCCTACCAGGACATCCTCGGAAAGTATTTATT
CTAGGCCAGGCTCCAGTATTCCTGGCTCACCAGGTCATACTATCTATGCAAAAGTAGACAATGAGATCCTGGATTACAAGGATTTAGCAG
CCATTCCGAAGGTCAAGGCAATTTATGACATTGAACGTCCAGATCTTATTACCTATGAGCCTTTCTACACTTCGGGCTATGATGACAAAC
AGGAGAGACAGAGCCTTGGAGAGTCTCCGAGGACTTTGTCTCCTACTCCATCAGCAGAAGGGTACCAGGATGTTCGGGATCGGATGATCC
ATCGGTCCACGAGCCAGGGCTCCATCAACTCCCCTGTGTACAGCCGCCACAGCTACACTCCAACCACGTCCCGCTCTCCCCAGCATTTCC
ACAGACCTGGCAATGAGCCGTCCAGCGGCCGGAACTCCCCTCTCCCTTACCGGCCAGACAGCCGCCCTCTAACTCCAACTTACGCTCAGG
CCCCTAAACATTTCCATGTTCCAGATCAAGGAATCAACATTTACCGAAAGCCACCCATCTACAAACAGCATGCTGCCTTGGCAGCCCAGA
GCAAGTCCTCAGAAGATATCATCAAGTTTTCCAAGTTCCCAGCAGCCCAGGCACCAGACCCCAGCGAGACACCAAAGATTGAGACGGACC
ACTGGCCTGGTCCCCCCTCATTTGCTGTCGTAGGACCTGACATGAAACGCAGATCTAGTGGCAGAGAGGAAGATGATGAGGAACTTCTGA
GACGTCGGCAGCTTCAAGAAGAGCAATTAATGAAGCTTAACTCAGGCCTGGGACAGTTGATCTTGAAAGAAGAGATGGAGAAAGAGAGCC
GGGAAAGGTCATCTCTGTTAGCCAGTCGCTACGATTCTCCCATCAACTCAGCTTCACATATTCCATCATCTAAAACTGCATCTCTCCCTG
GCTATGGAAGAAATGGGCTTCACCGGCCTGTTTCTACCGACTTCGCTCAGTATAACAGCTATGGGGATGTCAGCGGGGGAGTGCGAGATT
ACCAGACACTCCCAGATGGCCACATGCCTGCAATGAGAATGGACCGAGGAGTGTCTATGCCCAACATGTTGGAACCAAAGGTAGACGTCG
TGGACACTGGTTCAGGATGGACCCCACTCATGAGAGTCTCTGCGGTGTCGGGAAATCAGAGGGTGGCCTCTCTTCTAATTGATGCTGGGG
CCAATGTGAATGTGAAGGACAGAAATGGAAAGACGCCCCTTATGGTGGCTGTGTTAAATAATCATGAAGAGTTAGTTCAGTTACTTCTTG
ACAAAGGGGCAGATGCAAGTGTAAAAAATGAGTTCGGCAAAGGTGTCCTAGAAATGGCCAGAGTTTTTGACAGACAGAGTGTAGTCTCCT
TATTAGAAGAAAGGAAAAAAAAGCAGAGGCCAAAGAAGTCTTGTGTCTGCTGATGAGAGCACCACTCATCTGCGAAACGCACGTAAAACA
AAGTGAACCGTGACTGTTAAACTAGGGATGGGAAATTCTGCATCTTGGGGGGCTGTACATTTATTTATTTAGTTGAAGATTCACTGATCC

>509_509_2_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000277895_FANK1_chr10_127696975_ENST00000368695_length(amino acids)=830AA_BP=720
MEIHAKMPAFLGLKCLGKLCSSEKSKVTSSERTSARGSNRKRLIVEDRRVSGTSFTAHRRATITHLLYLCPKDYCPRGRVCNSVDPFVAH
PQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTLDYQRMYGTRCHGCGEFVEGEVVTALG
KTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQALLALDKQWHLGCFKCKSCGKVLTGEY
ISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQGSTVWHPDCKQSTKTEEKLRPTRTSSE
SIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQERQSLGESPRTLSPTPSAEGYQDVRD
RMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQAPKHFHVPDQGINIYRKPPIYKQHAAL
AAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLRRRQLQEEQLMKLNSGLGQLILKEEME
KESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDYQTLPDGHMPAMRMDRGVSMPNMLEPK
VDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQS

--------------------------------------------------------------
>509_509_3_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000369252_FANK1_chr10_127696975_ENST00000368693_length(transcript)=2749nt_BP=2264nt
GTCATTGAGCTGATGTGCTTTTGCAAGGGGTCTCTTTAGAAGTGGTAGGGGCAGGGTCGAGAGAAGAAGGGGATGCAGAATCTGTACATG
AGGAAGGAGCCAGAGTCACTCAGGAAACTCCTCATTCTTCCTGCGCTGGCTGTGGCACACCCACCGGTGGCACACCCCTCCCTCGGGTCC
AGTTCAGCCCACAGACTCCTGGGAGGAGAGCCAGGGCCCCAGCCTCTCCTTTGAGGAGTGTTGCAGCCTTTCTGTGTGCCAGATGCCTAG
TGAAGAAAAGCTGAAACCCTGGAGCTTTGTGCATGTTAATGACCTTGGAAATGACTGAGCTCACGGACCCTCATCACACCATGGGAGACT
ACAAAGTGGCCCACCCTCAGGACCCTCACCACCCATCAGAGAAGCCTGTCATTCACTGCCATAAATGTGGGGAGCCTTGCAAGGGTGAAG
TGCTTCGGGTCCAGACCAAACATTTCCACATCAAGTGTTTCACCTGCAAAGTGTGTGGCTGTGACCTGGCACAAGGGGGCTTCTTCATAA
AGAACGGAGAGTATCTCTGCACCCTGGACTACCAGCGGATGTACGGGACACGCTGCCATGGCTGTGGGGAGTTCGTGGAGGGCGAAGTGG
TGACTGCTCTGGGCAAGACCTACCATCCCAATTGCTTTGCTTGTACTATCTGCAAGCGCCCGTTTCCACCCGGAGACCGAGTCACATTCA
ATGGGAGAGACTGCCTTTGTCAACTCTGTGCACAGCCGATGTCGTCCAGTCCGAAAGAAACCACCTTCTCCAGCAATTGTGCCGGCTGCG
GAAGAGATATCAAGAATGGGCAGGCGCTGCTGGCGCTGGATAAGCAGTGGCACTTGGGGTGCTTTAAATGCAAGTCCTGCGGGAAGGTCC
TCACCGGGGAGTACATCAGCAAGGATGGTGCTCCGTACTGTGAAAAGGACTACCAGGGACTCTTTGGGGTGAAATGTGAGGCGTGTCACC
AGTTTATCACAGGGAAAGTCCTGGAGGCAGGTGACAAACATTACCACCCCAGCTGTGCACGATGCAGCAGATGCAACCAGATGTTCACAG
AAGGAGAGGAAATGTATCTTCAAGGCTCCACCGTTTGGCATCCCGACTGTAAGCAATCTACGAAGACCGAGGAAAAGCTGCGGCCTACCA
GGACATCCTCGGAAAGTATTTATTCTAGGCCAGGCTCCAGTATTCCTGGCTCACCAGGTCATACTATCTATGCAAAAGTAGACAATGAGA
TCCTGGATTACAAGGATTTAGCAGCCATTCCGAAGGTCAAGGCAATTTATGACATTGAACGTCCAGATCTTATTACCTATGAGCCTTTCT
ACACTTCGGGCTATGATGACAAACAGGAGAGACAGAGCCTTGGAGAGTCTCCGAGGACTTTGTCTCCTACTCCATCAGCAGAAGGGTACC
AGGATGTTCGGGATCGGATGATCCATCGGTCCACGAGCCAGGGCTCCATCAACTCCCCTGTGTACAGCCGCCACAGCTACACTCCAACCA
CGTCCCGCTCTCCCCAGCATTTCCACAGACCTGGCAATGAGCCGTCCAGCGGCCGGAACTCCCCTCTCCCTTACCGGCCAGACAGCCGCC
CTCTAACTCCAACTTACGCTCAGGCCCCTAAACATTTCCATGTTCCAGATCAAGGAATCAACATTTACCGAAAGCCACCCATCTACAAAC
AGCATGCTGCCTTGGCAGCCCAGAGCAAGTCCTCAGAAGATATCATCAAGTTTTCCAAGTTCCCAGCAGCCCAGGCACCAGACCCCAGCG
AGACACCAAAGATTGAGACGGACCACTGGCCTGGTCCCCCCTCATTTGCTGTCGTAGGACCTGACATGAAACGCAGATCTAGTGGCAGAG
AGGAAGATGATGAGGAACTTCTGAGACGTCGGCAGCTTCAAGAAGAGCAATTAATGAAGCTTAACTCAGGCCTGGGACAGTTGATCTTGA
AAGAAGAGATGGAGAAAGAGAGCCGGGAAAGGTCATCTCTGTTAGCCAGTCGCTACGATTCTCCCATCAACTCAGCTTCACATATTCCAT
CATCTAAAACTGCATCTCTCCCTGGCTATGGAAGAAATGGGCTTCACCGGCCTGTTTCTACCGACTTCGCTCAGTATAACAGCTATGGGG
ATGTCAGCGGGGGAGTGCGAGATTACCAGACACTCCCAGATGGCCACATGCCTGCAATGAGAATGGACCGAGGAGTGTCTATGCCCAACA
TGTTGGAACCAAAGGTAGACGTCGTGGACACTGGTTCAGGATGGACCCCACTCATGAGAGTCTCTGCGGTGTCGGGAAATCAGAGGGTGG
CCTCTCTTCTAATTGATGCTGGGGCCAATGTGAATGTGAAGGACAGAAATGGAAAGACGCCCCTTATGGTGGCTGTGTTAAATAATCATG
AAGAGTTAGTTCAGTTACTTCTTGACAAAGGGGCAGATGCAAGTGTAAAAAATGAGTTCGGCAAAGGTGTCCTAGAAATGGCCAGAGTTT
TTGACAGACAGAGTGTAGTCTCCTTATTAGAAGAAAGGAAAAAAAAGCAGAGGCCAAAGAAGTCTTGTGTCTGCTGATGAGAGCACCACT
CATCTGCGAAACGCACGTAAAACAAAGTGAACCGTGACTGTTAAACTAGGGATGGGAAATTCTGCATCTTGGGGGGCTGTACATTTATTT

>509_509_3_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000369252_FANK1_chr10_127696975_ENST00000368693_length(amino acids)=766AA_BP=656
MCMLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTL
DYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQA
LLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQG
STVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQ
ERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQA
PKHFHVPDQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLR
RRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDY
QTLPDGHMPAMRMDRGVSMPNMLEPKVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLD

--------------------------------------------------------------
>509_509_4_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000369252_FANK1_chr10_127696975_ENST00000368695_length(transcript)=2751nt_BP=2264nt
GTCATTGAGCTGATGTGCTTTTGCAAGGGGTCTCTTTAGAAGTGGTAGGGGCAGGGTCGAGAGAAGAAGGGGATGCAGAATCTGTACATG
AGGAAGGAGCCAGAGTCACTCAGGAAACTCCTCATTCTTCCTGCGCTGGCTGTGGCACACCCACCGGTGGCACACCCCTCCCTCGGGTCC
AGTTCAGCCCACAGACTCCTGGGAGGAGAGCCAGGGCCCCAGCCTCTCCTTTGAGGAGTGTTGCAGCCTTTCTGTGTGCCAGATGCCTAG
TGAAGAAAAGCTGAAACCCTGGAGCTTTGTGCATGTTAATGACCTTGGAAATGACTGAGCTCACGGACCCTCATCACACCATGGGAGACT
ACAAAGTGGCCCACCCTCAGGACCCTCACCACCCATCAGAGAAGCCTGTCATTCACTGCCATAAATGTGGGGAGCCTTGCAAGGGTGAAG
TGCTTCGGGTCCAGACCAAACATTTCCACATCAAGTGTTTCACCTGCAAAGTGTGTGGCTGTGACCTGGCACAAGGGGGCTTCTTCATAA
AGAACGGAGAGTATCTCTGCACCCTGGACTACCAGCGGATGTACGGGACACGCTGCCATGGCTGTGGGGAGTTCGTGGAGGGCGAAGTGG
TGACTGCTCTGGGCAAGACCTACCATCCCAATTGCTTTGCTTGTACTATCTGCAAGCGCCCGTTTCCACCCGGAGACCGAGTCACATTCA
ATGGGAGAGACTGCCTTTGTCAACTCTGTGCACAGCCGATGTCGTCCAGTCCGAAAGAAACCACCTTCTCCAGCAATTGTGCCGGCTGCG
GAAGAGATATCAAGAATGGGCAGGCGCTGCTGGCGCTGGATAAGCAGTGGCACTTGGGGTGCTTTAAATGCAAGTCCTGCGGGAAGGTCC
TCACCGGGGAGTACATCAGCAAGGATGGTGCTCCGTACTGTGAAAAGGACTACCAGGGACTCTTTGGGGTGAAATGTGAGGCGTGTCACC
AGTTTATCACAGGGAAAGTCCTGGAGGCAGGTGACAAACATTACCACCCCAGCTGTGCACGATGCAGCAGATGCAACCAGATGTTCACAG
AAGGAGAGGAAATGTATCTTCAAGGCTCCACCGTTTGGCATCCCGACTGTAAGCAATCTACGAAGACCGAGGAAAAGCTGCGGCCTACCA
GGACATCCTCGGAAAGTATTTATTCTAGGCCAGGCTCCAGTATTCCTGGCTCACCAGGTCATACTATCTATGCAAAAGTAGACAATGAGA
TCCTGGATTACAAGGATTTAGCAGCCATTCCGAAGGTCAAGGCAATTTATGACATTGAACGTCCAGATCTTATTACCTATGAGCCTTTCT
ACACTTCGGGCTATGATGACAAACAGGAGAGACAGAGCCTTGGAGAGTCTCCGAGGACTTTGTCTCCTACTCCATCAGCAGAAGGGTACC
AGGATGTTCGGGATCGGATGATCCATCGGTCCACGAGCCAGGGCTCCATCAACTCCCCTGTGTACAGCCGCCACAGCTACACTCCAACCA
CGTCCCGCTCTCCCCAGCATTTCCACAGACCTGGCAATGAGCCGTCCAGCGGCCGGAACTCCCCTCTCCCTTACCGGCCAGACAGCCGCC
CTCTAACTCCAACTTACGCTCAGGCCCCTAAACATTTCCATGTTCCAGATCAAGGAATCAACATTTACCGAAAGCCACCCATCTACAAAC
AGCATGCTGCCTTGGCAGCCCAGAGCAAGTCCTCAGAAGATATCATCAAGTTTTCCAAGTTCCCAGCAGCCCAGGCACCAGACCCCAGCG
AGACACCAAAGATTGAGACGGACCACTGGCCTGGTCCCCCCTCATTTGCTGTCGTAGGACCTGACATGAAACGCAGATCTAGTGGCAGAG
AGGAAGATGATGAGGAACTTCTGAGACGTCGGCAGCTTCAAGAAGAGCAATTAATGAAGCTTAACTCAGGCCTGGGACAGTTGATCTTGA
AAGAAGAGATGGAGAAAGAGAGCCGGGAAAGGTCATCTCTGTTAGCCAGTCGCTACGATTCTCCCATCAACTCAGCTTCACATATTCCAT
CATCTAAAACTGCATCTCTCCCTGGCTATGGAAGAAATGGGCTTCACCGGCCTGTTTCTACCGACTTCGCTCAGTATAACAGCTATGGGG
ATGTCAGCGGGGGAGTGCGAGATTACCAGACACTCCCAGATGGCCACATGCCTGCAATGAGAATGGACCGAGGAGTGTCTATGCCCAACA
TGTTGGAACCAAAGGTAGACGTCGTGGACACTGGTTCAGGATGGACCCCACTCATGAGAGTCTCTGCGGTGTCGGGAAATCAGAGGGTGG
CCTCTCTTCTAATTGATGCTGGGGCCAATGTGAATGTGAAGGACAGAAATGGAAAGACGCCCCTTATGGTGGCTGTGTTAAATAATCATG
AAGAGTTAGTTCAGTTACTTCTTGACAAAGGGGCAGATGCAAGTGTAAAAAATGAGTTCGGCAAAGGTGTCCTAGAAATGGCCAGAGTTT
TTGACAGACAGAGTGTAGTCTCCTTATTAGAAGAAAGGAAAAAAAAGCAGAGGCCAAAGAAGTCTTGTGTCTGCTGATGAGAGCACCACT
CATCTGCGAAACGCACGTAAAACAAAGTGAACCGTGACTGTTAAACTAGGGATGGGAAATTCTGCATCTTGGGGGGCTGTACATTTATTT

>509_509_4_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000369252_FANK1_chr10_127696975_ENST00000368695_length(amino acids)=766AA_BP=656
MCMLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTL
DYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQA
LLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQG
STVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQ
ERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQA
PKHFHVPDQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLR
RRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDY
QTLPDGHMPAMRMDRGVSMPNMLEPKVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLD

--------------------------------------------------------------
>509_509_5_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000533213_FANK1_chr10_127696975_ENST00000368693_length(transcript)=2749nt_BP=2264nt
GTCATTGAGCTGATGTGCTTTTGCAAGGGGTCTCTTTAGAAGTGGTAGGGGCAGGGTCGAGAGAAGAAGGGGATGCAGAATCTGTACATG
AGGAAGGAGCCAGAGTCACTCAGGAAACTCCTCATTCTTCCTGCGCTGGCTGTGGCACACCCACCGGTGGCACACCCCTCCCTCGGGTCC
AGTTCAGCCCACAGACTCCTGGGAGGAGAGCCAGGGCCCCAGCCTCTCCTTTGAGGAGTGTTGCAGCCTTTCTGTGTGCCAGATGCCTAG
TGAAGAAAAGCTGAAACCCTGGAGCTTTGTGCATGTTAATGACCTTGGAAATGACTGAGCTCACGGACCCTCATCACACCATGGGAGACT
ACAAAGTGGCCCACCCTCAGGACCCTCACCACCCATCAGAGAAGCCTGTCATTCACTGCCATAAATGTGGGGAGCCTTGCAAGGGTGAAG
TGCTTCGGGTCCAGACCAAACATTTCCACATCAAGTGTTTCACCTGCAAAGTGTGTGGCTGTGACCTGGCACAAGGGGGCTTCTTCATAA
AGAACGGAGAGTATCTCTGCACCCTGGACTACCAGCGGATGTACGGGACACGCTGCCATGGCTGTGGGGAGTTCGTGGAGGGCGAAGTGG
TGACTGCTCTGGGCAAGACCTACCATCCCAATTGCTTTGCTTGTACTATCTGCAAGCGCCCGTTTCCACCCGGAGACCGAGTCACATTCA
ATGGGAGAGACTGCCTTTGTCAACTCTGTGCACAGCCGATGTCGTCCAGTCCGAAAGAAACCACCTTCTCCAGCAATTGTGCCGGCTGCG
GAAGAGATATCAAGAATGGGCAGGCGCTGCTGGCGCTGGATAAGCAGTGGCACTTGGGGTGCTTTAAATGCAAGTCCTGCGGGAAGGTCC
TCACCGGGGAGTACATCAGCAAGGATGGTGCTCCGTACTGTGAAAAGGACTACCAGGGACTCTTTGGGGTGAAATGTGAGGCGTGTCACC
AGTTTATCACAGGGAAAGTCCTGGAGGCAGGTGACAAACATTACCACCCCAGCTGTGCACGATGCAGCAGATGCAACCAGATGTTCACAG
AAGGAGAGGAAATGTATCTTCAAGGCTCCACCGTTTGGCATCCCGACTGTAAGCAATCTACGAAGACCGAGGAAAAGCTGCGGCCTACCA
GGACATCCTCGGAAAGTATTTATTCTAGGCCAGGCTCCAGTATTCCTGGCTCACCAGGTCATACTATCTATGCAAAAGTAGACAATGAGA
TCCTGGATTACAAGGATTTAGCAGCCATTCCGAAGGTCAAGGCAATTTATGACATTGAACGTCCAGATCTTATTACCTATGAGCCTTTCT
ACACTTCGGGCTATGATGACAAACAGGAGAGACAGAGCCTTGGAGAGTCTCCGAGGACTTTGTCTCCTACTCCATCAGCAGAAGGGTACC
AGGATGTTCGGGATCGGATGATCCATCGGTCCACGAGCCAGGGCTCCATCAACTCCCCTGTGTACAGCCGCCACAGCTACACTCCAACCA
CGTCCCGCTCTCCCCAGCATTTCCACAGACCTGGCAATGAGCCGTCCAGCGGCCGGAACTCCCCTCTCCCTTACCGGCCAGACAGCCGCC
CTCTAACTCCAACTTACGCTCAGGCCCCTAAACATTTCCATGTTCCAGATCAAGGAATCAACATTTACCGAAAGCCACCCATCTACAAAC
AGCATGCTGCCTTGGCAGCCCAGAGCAAGTCCTCAGAAGATATCATCAAGTTTTCCAAGTTCCCAGCAGCCCAGGCACCAGACCCCAGCG
AGACACCAAAGATTGAGACGGACCACTGGCCTGGTCCCCCCTCATTTGCTGTCGTAGGACCTGACATGAAACGCAGATCTAGTGGCAGAG
AGGAAGATGATGAGGAACTTCTGAGACGTCGGCAGCTTCAAGAAGAGCAATTAATGAAGCTTAACTCAGGCCTGGGACAGTTGATCTTGA
AAGAAGAGATGGAGAAAGAGAGCCGGGAAAGGTCATCTCTGTTAGCCAGTCGCTACGATTCTCCCATCAACTCAGCTTCACATATTCCAT
CATCTAAAACTGCATCTCTCCCTGGCTATGGAAGAAATGGGCTTCACCGGCCTGTTTCTACCGACTTCGCTCAGTATAACAGCTATGGGG
ATGTCAGCGGGGGAGTGCGAGATTTCCAGACACTCCCAGATGGCCACATGCCTGCAATGAGAATGGACCGAGGAGTGTCTATGCCCAACA
TGTTGGAACCAAAGGTAGACGTCGTGGACACTGGTTCAGGATGGACCCCACTCATGAGAGTCTCTGCGGTGTCGGGAAATCAGAGGGTGG
CCTCTCTTCTAATTGATGCTGGGGCCAATGTGAATGTGAAGGACAGAAATGGAAAGACGCCCCTTATGGTGGCTGTGTTAAATAATCATG
AAGAGTTAGTTCAGTTACTTCTTGACAAAGGGGCAGATGCAAGTGTAAAAAATGAGTTCGGCAAAGGTGTCCTAGAAATGGCCAGAGTTT
TTGACAGACAGAGTGTAGTCTCCTTATTAGAAGAAAGGAAAAAAAAGCAGAGGCCAAAGAAGTCTTGTGTCTGCTGATGAGAGCACCACT
CATCTGCGAAACGCACGTAAAACAAAGTGAACCGTGACTGTTAAACTAGGGATGGGAAATTCTGCATCTTGGGGGGCTGTACATTTATTT

>509_509_5_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000533213_FANK1_chr10_127696975_ENST00000368693_length(amino acids)=766AA_BP=656
MCMLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTL
DYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQA
LLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQG
STVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQ
ERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQA
PKHFHVPDQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLR
RRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDF
QTLPDGHMPAMRMDRGVSMPNMLEPKVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLD

--------------------------------------------------------------
>509_509_6_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000533213_FANK1_chr10_127696975_ENST00000368695_length(transcript)=2751nt_BP=2264nt
GTCATTGAGCTGATGTGCTTTTGCAAGGGGTCTCTTTAGAAGTGGTAGGGGCAGGGTCGAGAGAAGAAGGGGATGCAGAATCTGTACATG
AGGAAGGAGCCAGAGTCACTCAGGAAACTCCTCATTCTTCCTGCGCTGGCTGTGGCACACCCACCGGTGGCACACCCCTCCCTCGGGTCC
AGTTCAGCCCACAGACTCCTGGGAGGAGAGCCAGGGCCCCAGCCTCTCCTTTGAGGAGTGTTGCAGCCTTTCTGTGTGCCAGATGCCTAG
TGAAGAAAAGCTGAAACCCTGGAGCTTTGTGCATGTTAATGACCTTGGAAATGACTGAGCTCACGGACCCTCATCACACCATGGGAGACT
ACAAAGTGGCCCACCCTCAGGACCCTCACCACCCATCAGAGAAGCCTGTCATTCACTGCCATAAATGTGGGGAGCCTTGCAAGGGTGAAG
TGCTTCGGGTCCAGACCAAACATTTCCACATCAAGTGTTTCACCTGCAAAGTGTGTGGCTGTGACCTGGCACAAGGGGGCTTCTTCATAA
AGAACGGAGAGTATCTCTGCACCCTGGACTACCAGCGGATGTACGGGACACGCTGCCATGGCTGTGGGGAGTTCGTGGAGGGCGAAGTGG
TGACTGCTCTGGGCAAGACCTACCATCCCAATTGCTTTGCTTGTACTATCTGCAAGCGCCCGTTTCCACCCGGAGACCGAGTCACATTCA
ATGGGAGAGACTGCCTTTGTCAACTCTGTGCACAGCCGATGTCGTCCAGTCCGAAAGAAACCACCTTCTCCAGCAATTGTGCCGGCTGCG
GAAGAGATATCAAGAATGGGCAGGCGCTGCTGGCGCTGGATAAGCAGTGGCACTTGGGGTGCTTTAAATGCAAGTCCTGCGGGAAGGTCC
TCACCGGGGAGTACATCAGCAAGGATGGTGCTCCGTACTGTGAAAAGGACTACCAGGGACTCTTTGGGGTGAAATGTGAGGCGTGTCACC
AGTTTATCACAGGGAAAGTCCTGGAGGCAGGTGACAAACATTACCACCCCAGCTGTGCACGATGCAGCAGATGCAACCAGATGTTCACAG
AAGGAGAGGAAATGTATCTTCAAGGCTCCACCGTTTGGCATCCCGACTGTAAGCAATCTACGAAGACCGAGGAAAAGCTGCGGCCTACCA
GGACATCCTCGGAAAGTATTTATTCTAGGCCAGGCTCCAGTATTCCTGGCTCACCAGGTCATACTATCTATGCAAAAGTAGACAATGAGA
TCCTGGATTACAAGGATTTAGCAGCCATTCCGAAGGTCAAGGCAATTTATGACATTGAACGTCCAGATCTTATTACCTATGAGCCTTTCT
ACACTTCGGGCTATGATGACAAACAGGAGAGACAGAGCCTTGGAGAGTCTCCGAGGACTTTGTCTCCTACTCCATCAGCAGAAGGGTACC
AGGATGTTCGGGATCGGATGATCCATCGGTCCACGAGCCAGGGCTCCATCAACTCCCCTGTGTACAGCCGCCACAGCTACACTCCAACCA
CGTCCCGCTCTCCCCAGCATTTCCACAGACCTGGCAATGAGCCGTCCAGCGGCCGGAACTCCCCTCTCCCTTACCGGCCAGACAGCCGCC
CTCTAACTCCAACTTACGCTCAGGCCCCTAAACATTTCCATGTTCCAGATCAAGGAATCAACATTTACCGAAAGCCACCCATCTACAAAC
AGCATGCTGCCTTGGCAGCCCAGAGCAAGTCCTCAGAAGATATCATCAAGTTTTCCAAGTTCCCAGCAGCCCAGGCACCAGACCCCAGCG
AGACACCAAAGATTGAGACGGACCACTGGCCTGGTCCCCCCTCATTTGCTGTCGTAGGACCTGACATGAAACGCAGATCTAGTGGCAGAG
AGGAAGATGATGAGGAACTTCTGAGACGTCGGCAGCTTCAAGAAGAGCAATTAATGAAGCTTAACTCAGGCCTGGGACAGTTGATCTTGA
AAGAAGAGATGGAGAAAGAGAGCCGGGAAAGGTCATCTCTGTTAGCCAGTCGCTACGATTCTCCCATCAACTCAGCTTCACATATTCCAT
CATCTAAAACTGCATCTCTCCCTGGCTATGGAAGAAATGGGCTTCACCGGCCTGTTTCTACCGACTTCGCTCAGTATAACAGCTATGGGG
ATGTCAGCGGGGGAGTGCGAGATTTCCAGACACTCCCAGATGGCCACATGCCTGCAATGAGAATGGACCGAGGAGTGTCTATGCCCAACA
TGTTGGAACCAAAGGTAGACGTCGTGGACACTGGTTCAGGATGGACCCCACTCATGAGAGTCTCTGCGGTGTCGGGAAATCAGAGGGTGG
CCTCTCTTCTAATTGATGCTGGGGCCAATGTGAATGTGAAGGACAGAAATGGAAAGACGCCCCTTATGGTGGCTGTGTTAAATAATCATG
AAGAGTTAGTTCAGTTACTTCTTGACAAAGGGGCAGATGCAAGTGTAAAAAATGAGTTCGGCAAAGGTGTCCTAGAAATGGCCAGAGTTT
TTGACAGACAGAGTGTAGTCTCCTTATTAGAAGAAAGGAAAAAAAAGCAGAGGCCAAAGAAGTCTTGTGTCTGCTGATGAGAGCACCACT
CATCTGCGAAACGCACGTAAAACAAAGTGAACCGTGACTGTTAAACTAGGGATGGGAAATTCTGCATCTTGGGGGGCTGTACATTTATTT

>509_509_6_ABLIM1-FANK1_ABLIM1_chr10_116198934_ENST00000533213_FANK1_chr10_127696975_ENST00000368695_length(amino acids)=766AA_BP=656
MCMLMTLEMTELTDPHHTMGDYKVAHPQDPHHPSEKPVIHCHKCGEPCKGEVLRVQTKHFHIKCFTCKVCGCDLAQGGFFIKNGEYLCTL
DYQRMYGTRCHGCGEFVEGEVVTALGKTYHPNCFACTICKRPFPPGDRVTFNGRDCLCQLCAQPMSSSPKETTFSSNCAGCGRDIKNGQA
LLALDKQWHLGCFKCKSCGKVLTGEYISKDGAPYCEKDYQGLFGVKCEACHQFITGKVLEAGDKHYHPSCARCSRCNQMFTEGEEMYLQG
STVWHPDCKQSTKTEEKLRPTRTSSESIYSRPGSSIPGSPGHTIYAKVDNEILDYKDLAAIPKVKAIYDIERPDLITYEPFYTSGYDDKQ
ERQSLGESPRTLSPTPSAEGYQDVRDRMIHRSTSQGSINSPVYSRHSYTPTTSRSPQHFHRPGNEPSSGRNSPLPYRPDSRPLTPTYAQA
PKHFHVPDQGINIYRKPPIYKQHAALAAQSKSSEDIIKFSKFPAAQAPDPSETPKIETDHWPGPPSFAVVGPDMKRRSSGREEDDEELLR
RRQLQEEQLMKLNSGLGQLILKEEMEKESRERSSLLASRYDSPINSASHIPSSKTASLPGYGRNGLHRPVSTDFAQYNSYGDVSGGVRDF
QTLPDGHMPAMRMDRGVSMPNMLEPKVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLD

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Fusion Gene PPI Analysis for ABLIM1-FANK1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABLIM1-FANK1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABLIM1-FANK1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource