Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ANXA8L2-IQCA1 (FusionGDB2 ID:5095)

Fusion Gene Summary for ANXA8L2-IQCA1

Fusion gene summary

Fusion gene information	Fusion gene name: ANXA8L2-IQCA1
	Fusion gene ID: 5095
		Hgene	Tgene
	Gene symbol	ANXA8L2	IQCA1
	Gene ID	728113	79781
	Gene name	annexin A8 like 1	IQ motif containing with AAA domain 1
	Synonyms	ANXA8\|ANXA8L2\|VAC-beta\|bA145E20.2	4930465P12Rik\|DRC11\|IQCA
	Cytomap	10q11.22	2q37.2-q37.3
	Type of gene	protein-coding	protein-coding
	Description	annexin A8-like protein 1annexin A8-like protein 2annexin A8L2annexin VIIIannexin-8vascular anticoagulant-beta	dynein regulatory complex protein 11IQ and AAA domain-containing protein 1dynein regulatory complex subunit 11
	Modification date	20200313	20200313
	UniProtAcc	.	A6NCM1
	Ensembl transtripts involved in fusion gene	ENST00000340243, ENST00000374277, ENST00000449464, ENST00000538825,	ENST00000465621, ENST00000309507, ENST00000409907, ENST00000431676,
Fusion gene scores	* DoF score	2 X 1 X 2=4	3 X 3 X 2=18
	# samples	2	3
	** MAII score	log2(2/4*10)=2.32192809488736	log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: ANXA8L2 [Title/Abstract] AND IQCA1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ANXA8L2(47747132)-IQCA1(237247025), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across ANXA8L2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across IQCA1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-BH-A0HB	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-

Top

Fusion Gene ORF analysis for ANXA8L2-IQCA1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000340243	ENST00000465621	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
5CDS-intron	ENST00000374277	ENST00000465621	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
5CDS-intron	ENST00000449464	ENST00000465621	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
5CDS-intron	ENST00000538825	ENST00000465621	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000340243	ENST00000309507	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000340243	ENST00000409907	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000340243	ENST00000431676	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000374277	ENST00000309507	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000374277	ENST00000409907	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000374277	ENST00000431676	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000449464	ENST00000309507	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000449464	ENST00000409907	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000449464	ENST00000431676	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000538825	ENST00000309507	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000538825	ENST00000409907	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-
In-frame	ENST00000538825	ENST00000431676	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000340243	ANXA8L2	chr10	47747132	+	ENST00000409907	IQCA1	chr2	237247025	-	1247	197	802	2	267
ENST00000340243	ANXA8L2	chr10	47747132	+	ENST00000309507	IQCA1	chr2	237247025	-	1245	197	802	2	267
ENST00000340243	ANXA8L2	chr10	47747132	+	ENST00000431676	IQCA1	chr2	237247025	-	801	197	32	709	225
ENST00000374277	ANXA8L2	chr10	47747132	+	ENST00000409907	IQCA1	chr2	237247025	-	1193	143	748	2	249
ENST00000374277	ANXA8L2	chr10	47747132	+	ENST00000309507	IQCA1	chr2	237247025	-	1191	143	748	2	249
ENST00000374277	ANXA8L2	chr10	47747132	+	ENST00000431676	IQCA1	chr2	237247025	-	747	143	20	655	211
ENST00000449464	ANXA8L2	chr10	47747132	+	ENST00000409907	IQCA1	chr2	237247025	-	1154	104	709	2	236
ENST00000449464	ANXA8L2	chr10	47747132	+	ENST00000309507	IQCA1	chr2	237247025	-	1152	104	709	2	236
ENST00000449464	ANXA8L2	chr10	47747132	+	ENST00000431676	IQCA1	chr2	237247025	-	708	104	83	616	177
ENST00000538825	ANXA8L2	chr10	47747132	+	ENST00000409907	IQCA1	chr2	237247025	-	1147	97	702	1	234
ENST00000538825	ANXA8L2	chr10	47747132	+	ENST00000309507	IQCA1	chr2	237247025	-	1145	97	702	1	234
ENST00000538825	ANXA8L2	chr10	47747132	+	ENST00000431676	IQCA1	chr2	237247025	-	701	97	76	609	177

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000340243	ENST00000409907	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.003944084	0.99605596
ENST00000340243	ENST00000309507	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.003979797	0.99602026
ENST00000340243	ENST00000431676	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.01138741	0.9886126
ENST00000374277	ENST00000409907	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.003915988	0.996084
ENST00000374277	ENST00000309507	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.003977363	0.9960226
ENST00000374277	ENST00000431676	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.014450664	0.9855494
ENST00000449464	ENST00000409907	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.004321183	0.99567884
ENST00000449464	ENST00000309507	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.00434609	0.99565387
ENST00000449464	ENST00000431676	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.014415591	0.98558444
ENST00000538825	ENST00000409907	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.003975442	0.9960245
ENST00000538825	ENST00000309507	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.004001946	0.995998
ENST00000538825	ENST00000431676	ANXA8L2	chr10	47747132	+	IQCA1	chr2	237247025	-	0.014352551	0.98564744

Top

Fusion Genomic Features for ANXA8L2-IQCA1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for ANXA8L2-IQCA1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:47747132/chr2:237247025)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	IQCA1 A6NCM1
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ANXA8L2

chr10:47747132

chr2:237247025

ENST00000340243

177_249

277.0

Repeat

Annexin 3

Hgene

ANXA8L2

chr10:47747132

chr2:237247025

ENST00000340243

21_92

277.0

Repeat

Annexin 1

Hgene

ANXA8L2

chr10:47747132

chr2:237247025

ENST00000340243

253_324

277.0

Repeat

Annexin 4

Hgene

ANXA8L2

chr10:47747132

chr2:237247025

ENST00000340243

93_164

277.0

Repeat

Annexin 2

Hgene

ANXA8L2

chr10:47747132

chr2:237247025

ENST00000374277

177_249

328.0

Repeat

Annexin 3

Hgene

ANXA8L2

chr10:47747132

chr2:237247025

ENST00000374277

21_92

328.0

Repeat

Annexin 1

Hgene

ANXA8L2

chr10:47747132

chr2:237247025

ENST00000374277

253_324

328.0

Repeat

Annexin 4

Hgene

ANXA8L2

chr10:47747132

chr2:237247025

ENST00000374277

93_164

328.0

Repeat

Annexin 2

Tgene

IQCA1

chr10:47747132

chr2:237247025

ENST00000409907

351_487

652

823.0

Compositional bias

Note=Lys-rich

Tgene

IQCA1

chr10:47747132

chr2:237247025

ENST00000431676

351_487

611

782.0

Compositional bias

Note=Lys-rich

Tgene

IQCA1

chr10:47747132

chr2:237247025

ENST00000409907

207_236

652

823.0

Domain

Tgene

IQCA1

chr10:47747132

chr2:237247025

ENST00000431676

207_236

611

782.0

Domain

Tgene

IQCA1

chr10:47747132

chr2:237247025

ENST00000409907

575_582

652

823.0

Nucleotide binding

ATP

Tgene

IQCA1

chr10:47747132

chr2:237247025

ENST00000431676

575_582

611

782.0

Nucleotide binding

ATP

Top

Fusion Gene Sequence for ANXA8L2-IQCA1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>5095_5095_1_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000340243_IQCA1_chr2_237247025_ENST00000309507_length(transcript)=1245nt_BP=197nt
CGGGGGCGAGGGGGCGGCAGGCAGGTGTAGCGCTGCCCTGGGCGGGCTTGCACCCCCACACCCAAGTGAGCGGCCTGCTCACTCCTCAGC
TGCAGGAGCCAGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATCTCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGG
CCTGGTGGAAAGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAATCCTGAAACTCCTGAAACCAGATGACCGGATTCTGA
TTGTGGGGACCACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAGTTTACCAGAAAATTATTTTGGTGCCCAGACCAGACT
ATGCTTCCAGATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCCTCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGG
TCACTGACGGCTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCACAGATCAGAGAATCCGGCGGCAAATTCATAAACCTC
TCACTGCAGTTGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAGAGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAA
CTCCTCTGGGTAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGGCAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGA
AAAAGGCAAAAAAGAAAAAGTAATGCCTTTCTGAAGAACCATGCTTGAGTCTCTCTGGGATGGAGAGGACCCCAACTCGCCAAAGAAAAG
ATTCACCATTGCCCGCCTGAAGAAGCCCTCAGGGGAAGGAACTTAGCAGTGTGCAGGTGAGCTGATGCCGCAAACCCGCTAACCACTGCA
TGTGCTGTTATGCCTTTCCCAGGCTGGACACCTAGCTGGGTGTTCATCATAACTTTCCACAGCTTTAATCCACGCCAAGTTTGTATATAA
CTGAAATTCACTCTTGACACCCTCCACAGTCTTTCCAAGTTGGACTCTTCCTCTCATCAGTACTAGTTGTCAAATTTAAAATGTGACAGT
TAAAGAATATTCTAGTTTGACAATTAGTAAGCAATGAGTATATCATCAGTACACTAGCTTTTTATTAATCCATGTACACTGTATAGTATC

>5095_5095_1_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000340243_IQCA1_chr2_237247025_ENST00000309507_length(amino acids)=267AA_BP=1
MASWGPLHPRETQAWFFRKALLFLFCLFLFLLFPFPFVLCLFCAASCYRQGTFFTQRSFGIPVLKALFFLFVHWIHAGYRRNKLNCSERF
MNLPPDSLICEHAFNHFDYMSLGEAVSDLRQAADIQGTGEDSSIAFNDLLPQNVSGSIVWSGHQNNFLVNFAERLEFSIEGTPCGPHNQN

--------------------------------------------------------------
>5095_5095_2_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000340243_IQCA1_chr2_237247025_ENST00000409907_length(transcript)=1247nt_BP=197nt
CGGGGGCGAGGGGGCGGCAGGCAGGTGTAGCGCTGCCCTGGGCGGGCTTGCACCCCCACACCCAAGTGAGCGGCCTGCTCACTCCTCAGC
TGCAGGAGCCAGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATCTCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGG
CCTGGTGGAAAGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAATCCTGAAACTCCTGAAACCAGATGACCGGATTCTGA
TTGTGGGGACCACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAGTTTACCAGAAAATTATTTTGGTGCCCAGACCAGACT
ATGCTTCCAGATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCCTCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGG
TCACTGACGGCTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCACAGATCAGAGAATCCGGCGGCAAATTCATAAACCTC
TCACTGCAGTTGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAGAGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAA
CTCCTCTGGGTAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGGCAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGA
AAAAGGCAAAAAAGAAAAAGTAATGCCTTTCTGAAGAACCATGCTTGAGTCTCTCTGGGATGGAGAGGACCCCAACTCGCCAAAGAAAAG
ATTCACCATTGCCCGCCTGAAGAAGCCCTCAGGGGAAGGAACTTAGCAGTGTGCAGGTGAGCTGATGCCGCAAACCCGCTAACCACTGCA
TGTGCTGTTATGCCTTTCCCAGGCTGGACACCTAGCTGGGTGTTCATCATAACTTTCCACAGCTTTAATCCACGCCAAGTTTGTATATAA
CTGAAATTCACTCTTGACACCCTCCACAGTCTTTCCAAGTTGGACTCTTCCTCTCATCAGTACTAGTTGTCAAATTTAAAATGTGACAGT
TAAAGAATATTCTAGTTTGACAATTAGTAAGCAATGAGTATATCATCAGTACACTAGCTTTTTATTAATCCATGTACACTGTATAGTATC

>5095_5095_2_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000340243_IQCA1_chr2_237247025_ENST00000409907_length(amino acids)=267AA_BP=1
MASWGPLHPRETQAWFFRKALLFLFCLFLFLLFPFPFVLCLFCAASCYRQGTFFTQRSFGIPVLKALFFLFVHWIHAGYRRNKLNCSERF
MNLPPDSLICEHAFNHFDYMSLGEAVSDLRQAADIQGTGEDSSIAFNDLLPQNVSGSIVWSGHQNNFLVNFAERLEFSIEGTPCGPHNQN

--------------------------------------------------------------
>5095_5095_3_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000340243_IQCA1_chr2_237247025_ENST00000431676_length(transcript)=801nt_BP=197nt
CGGGGGCGAGGGGGCGGCAGGCAGGTGTAGCGCTGCCCTGGGCGGGCTTGCACCCCCACACCCAAGTGAGCGGCCTGCTCACTCCTCAGC
TGCAGGAGCCAGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATCTCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGG
CCTGGTGGAAAGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAATCCTGAAACTCCTGAAACCAGATGACCGGATTCTGA
TTGTGGGGACCACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAGTTTACCAGAAAATTATTTTGGTGCCCAGACCAGACT
ATGCTTCCAGATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCCTCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGG
TCACTGACGGCTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCACAGATCAGAGAATCCGGCGGCAAATTCATAAACCTC
TCACTGCAGTTGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAGAGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAA
CTCCTCTGGGTAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGGCAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGA

>5095_5095_3_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000340243_IQCA1_chr2_237247025_ENST00000431676_length(amino acids)=225AA_BP=55
MPWAGLHPHTQVSGLLTPQLQEPDVWSPSRGQPVSLHLREKGAPEVKEMAWWKAWNEPKRLKKHLPQILKLLKPDDRILIVGTTRRPFDA
ELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGHIVEVVKGVLTDQRIRRQIHKPLTAVEFITAIT

--------------------------------------------------------------
>5095_5095_4_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000374277_IQCA1_chr2_237247025_ENST00000309507_length(transcript)=1191nt_BP=143nt
CCCACACCCAAGTGAGCGGCCTGCTCACTCCTCAGCTGCAGGAGCCAGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATC
TCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGGCCTGGTGGAAAGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAA
TCCTGAAACTCCTGAAACCAGATGACCGGATTCTGATTGTGGGGACCACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAG
TTTACCAGAAAATTATTTTGGTGCCCAGACCAGACTATGCTTCCAGATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCC
TCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGGTCACTGACGGCTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCA
CAGATCAGAGAATCCGGCGGCAAATTCATAAACCTCTCACTGCAGTTGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAG
AGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAACTCCTCTGGGTAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGG
CAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGAAAAAGGCAAAAAAGAAAAAGTAATGCCTTTCTGAAGAACCATGCTTGAGTCTCT
CTGGGATGGAGAGGACCCCAACTCGCCAAAGAAAAGATTCACCATTGCCCGCCTGAAGAAGCCCTCAGGGGAAGGAACTTAGCAGTGTGC
AGGTGAGCTGATGCCGCAAACCCGCTAACCACTGCATGTGCTGTTATGCCTTTCCCAGGCTGGACACCTAGCTGGGTGTTCATCATAACT
TTCCACAGCTTTAATCCACGCCAAGTTTGTATATAACTGAAATTCACTCTTGACACCCTCCACAGTCTTTCCAAGTTGGACTCTTCCTCT
CATCAGTACTAGTTGTCAAATTTAAAATGTGACAGTTAAAGAATATTCTAGTTTGACAATTAGTAAGCAATGAGTATATCATCAGTACAC
TAGCTTTTTATTAATCCATGTACACTGTATAGTATCTTGCATCTATTTTAATAAATTAATTCTTTGCTCTAGTAATAGATTTTATATAAT

>5095_5095_4_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000374277_IQCA1_chr2_237247025_ENST00000309507_length(amino acids)=249AA_BP=1
MASWGPLHPRETQAWFFRKALLFLFCLFLFLLFPFPFVLCLFCAASCYRQGTFFTQRSFGIPVLKALFFLFVHWIHAGYRRNKLNCSERF
MNLPPDSLICEHAFNHFDYMSLGEAVSDLRQAADIQGTGEDSSIAFNDLLPQNVSGSIVWSGHQNNFLVNFAERLEFSIEGTPCGPHNQN

--------------------------------------------------------------
>5095_5095_5_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000374277_IQCA1_chr2_237247025_ENST00000409907_length(transcript)=1193nt_BP=143nt
CCCACACCCAAGTGAGCGGCCTGCTCACTCCTCAGCTGCAGGAGCCAGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATC
TCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGGCCTGGTGGAAAGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAA
TCCTGAAACTCCTGAAACCAGATGACCGGATTCTGATTGTGGGGACCACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAG
TTTACCAGAAAATTATTTTGGTGCCCAGACCAGACTATGCTTCCAGATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCC
TCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGGTCACTGACGGCTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCA
CAGATCAGAGAATCCGGCGGCAAATTCATAAACCTCTCACTGCAGTTGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAG
AGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAACTCCTCTGGGTAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGG
CAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGAAAAAGGCAAAAAAGAAAAAGTAATGCCTTTCTGAAGAACCATGCTTGAGTCTCT
CTGGGATGGAGAGGACCCCAACTCGCCAAAGAAAAGATTCACCATTGCCCGCCTGAAGAAGCCCTCAGGGGAAGGAACTTAGCAGTGTGC
AGGTGAGCTGATGCCGCAAACCCGCTAACCACTGCATGTGCTGTTATGCCTTTCCCAGGCTGGACACCTAGCTGGGTGTTCATCATAACT
TTCCACAGCTTTAATCCACGCCAAGTTTGTATATAACTGAAATTCACTCTTGACACCCTCCACAGTCTTTCCAAGTTGGACTCTTCCTCT
CATCAGTACTAGTTGTCAAATTTAAAATGTGACAGTTAAAGAATATTCTAGTTTGACAATTAGTAAGCAATGAGTATATCATCAGTACAC
TAGCTTTTTATTAATCCATGTACACTGTATAGTATCTTGCATCTATTTTAATAAATTAATTCTTTGCTCTAGTAATAGATTTTATATAAT

>5095_5095_5_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000374277_IQCA1_chr2_237247025_ENST00000409907_length(amino acids)=249AA_BP=1
MASWGPLHPRETQAWFFRKALLFLFCLFLFLLFPFPFVLCLFCAASCYRQGTFFTQRSFGIPVLKALFFLFVHWIHAGYRRNKLNCSERF
MNLPPDSLICEHAFNHFDYMSLGEAVSDLRQAADIQGTGEDSSIAFNDLLPQNVSGSIVWSGHQNNFLVNFAERLEFSIEGTPCGPHNQN

--------------------------------------------------------------
>5095_5095_6_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000374277_IQCA1_chr2_237247025_ENST00000431676_length(transcript)=747nt_BP=143nt
CCCACACCCAAGTGAGCGGCCTGCTCACTCCTCAGCTGCAGGAGCCAGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATC
TCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGGCCTGGTGGAAAGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAA
TCCTGAAACTCCTGAAACCAGATGACCGGATTCTGATTGTGGGGACCACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAG
TTTACCAGAAAATTATTTTGGTGCCCAGACCAGACTATGCTTCCAGATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCC
TCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGGTCACTGACGGCTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCA
CAGATCAGAGAATCCGGCGGCAAATTCATAAACCTCTCACTGCAGTTGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAG
AGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAACTCCTCTGGGTAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGG
CAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGAAAAAGGCAAAAAAGAAAAAGTAATGCCTTTCTGAAGAACCATGCTTGAGTCTCT

>5095_5095_6_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000374277_IQCA1_chr2_237247025_ENST00000431676_length(amino acids)=211AA_BP=41
MLTPQLQEPDVWSPSRGQPVSLHLREKGAPEVKEMAWWKAWNEPKRLKKHLPQILKLLKPDDRILIVGTTRRPFDAELQSFCKVYQKIIL
VPRPDYASRYVLWKQIIERNGGVLTSALNVSCLAKVTDGFTQGHIVEVVKGVLTDQRIRRQIHKPLTAVEFITAITSMNPVYKEEEESFK

--------------------------------------------------------------
>5095_5095_7_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000449464_IQCA1_chr2_237247025_ENST00000309507_length(transcript)=1152nt_BP=104nt
AGGAGCCAGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATCTCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGGCCT
GGTGGAAAGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAATCCTGAAACTCCTGAAACCAGATGACCGGATTCTGATTG
TGGGGACCACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAGTTTACCAGAAAATTATTTTGGTGCCCAGACCAGACTATG
CTTCCAGATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCCTCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGGTCA
CTGACGGCTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCACAGATCAGAGAATCCGGCGGCAAATTCATAAACCTCTCA
CTGCAGTTGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAGAGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAACTC
CTCTGGGTAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGGCAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGAAAA
AGGCAAAAAAGAAAAAGTAATGCCTTTCTGAAGAACCATGCTTGAGTCTCTCTGGGATGGAGAGGACCCCAACTCGCCAAAGAAAAGATT
CACCATTGCCCGCCTGAAGAAGCCCTCAGGGGAAGGAACTTAGCAGTGTGCAGGTGAGCTGATGCCGCAAACCCGCTAACCACTGCATGT
GCTGTTATGCCTTTCCCAGGCTGGACACCTAGCTGGGTGTTCATCATAACTTTCCACAGCTTTAATCCACGCCAAGTTTGTATATAACTG
AAATTCACTCTTGACACCCTCCACAGTCTTTCCAAGTTGGACTCTTCCTCTCATCAGTACTAGTTGTCAAATTTAAAATGTGACAGTTAA
AGAATATTCTAGTTTGACAATTAGTAAGCAATGAGTATATCATCAGTACACTAGCTTTTTATTAATCCATGTACACTGTATAGTATCTTG

>5095_5095_7_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000449464_IQCA1_chr2_237247025_ENST00000309507_length(amino acids)=236AA_BP=1
MASWGPLHPRETQAWFFRKALLFLFCLFLFLLFPFPFVLCLFCAASCYRQGTFFTQRSFGIPVLKALFFLFVHWIHAGYRRNKLNCSERF
MNLPPDSLICEHAFNHFDYMSLGEAVSDLRQAADIQGTGEDSSIAFNDLLPQNVSGSIVWSGHQNNFLVNFAERLEFSIEGTPCGPHNQN

--------------------------------------------------------------
>5095_5095_8_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000449464_IQCA1_chr2_237247025_ENST00000409907_length(transcript)=1154nt_BP=104nt
AGGAGCCAGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATCTCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGGCCT
GGTGGAAAGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAATCCTGAAACTCCTGAAACCAGATGACCGGATTCTGATTG
TGGGGACCACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAGTTTACCAGAAAATTATTTTGGTGCCCAGACCAGACTATG
CTTCCAGATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCCTCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGGTCA
CTGACGGCTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCACAGATCAGAGAATCCGGCGGCAAATTCATAAACCTCTCA
CTGCAGTTGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAGAGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAACTC
CTCTGGGTAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGGCAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGAAAA
AGGCAAAAAAGAAAAAGTAATGCCTTTCTGAAGAACCATGCTTGAGTCTCTCTGGGATGGAGAGGACCCCAACTCGCCAAAGAAAAGATT
CACCATTGCCCGCCTGAAGAAGCCCTCAGGGGAAGGAACTTAGCAGTGTGCAGGTGAGCTGATGCCGCAAACCCGCTAACCACTGCATGT
GCTGTTATGCCTTTCCCAGGCTGGACACCTAGCTGGGTGTTCATCATAACTTTCCACAGCTTTAATCCACGCCAAGTTTGTATATAACTG
AAATTCACTCTTGACACCCTCCACAGTCTTTCCAAGTTGGACTCTTCCTCTCATCAGTACTAGTTGTCAAATTTAAAATGTGACAGTTAA
AGAATATTCTAGTTTGACAATTAGTAAGCAATGAGTATATCATCAGTACACTAGCTTTTTATTAATCCATGTACACTGTATAGTATCTTG

>5095_5095_8_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000449464_IQCA1_chr2_237247025_ENST00000409907_length(amino acids)=236AA_BP=1
MASWGPLHPRETQAWFFRKALLFLFCLFLFLLFPFPFVLCLFCAASCYRQGTFFTQRSFGIPVLKALFFLFVHWIHAGYRRNKLNCSERF
MNLPPDSLICEHAFNHFDYMSLGEAVSDLRQAADIQGTGEDSSIAFNDLLPQNVSGSIVWSGHQNNFLVNFAERLEFSIEGTPCGPHNQN

--------------------------------------------------------------
>5095_5095_9_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000449464_IQCA1_chr2_237247025_ENST00000431676_length(transcript)=708nt_BP=104nt
AGGAGCCAGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATCTCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGGCCT
GGTGGAAAGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAATCCTGAAACTCCTGAAACCAGATGACCGGATTCTGATTG
TGGGGACCACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAGTTTACCAGAAAATTATTTTGGTGCCCAGACCAGACTATG
CTTCCAGATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCCTCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGGTCA
CTGACGGCTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCACAGATCAGAGAATCCGGCGGCAAATTCATAAACCTCTCA
CTGCAGTTGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAGAGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAACTC
CTCTGGGTAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGGCAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGAAAA

>5095_5095_9_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000449464_IQCA1_chr2_237247025_ENST00000431676_length(amino acids)=177AA_BP=7
MAWWKAWNEPKRLKKHLPQILKLLKPDDRILIVGTTRRPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLA

--------------------------------------------------------------
>5095_5095_10_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000538825_IQCA1_chr2_237247025_ENST00000309507_length(transcript)=1145nt_BP=97nt
AGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATCTCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGGCCTGGTGGAA
AGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAATCCTGAAACTCCTGAAACCAGATGACCGGATTCTGATTGTGGGGAC
CACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAGTTTACCAGAAAATTATTTTGGTGCCCAGACCAGACTATGCTTCCAG
ATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCCTCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGGTCACTGACGG
CTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCACAGATCAGAGAATCCGGCGGCAAATTCATAAACCTCTCACTGCAGT
TGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAGAGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAACTCCTCTGGG
TAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGGCAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGAAAAAGGCAAA
AAAGAAAAAGTAATGCCTTTCTGAAGAACCATGCTTGAGTCTCTCTGGGATGGAGAGGACCCCAACTCGCCAAAGAAAAGATTCACCATT
GCCCGCCTGAAGAAGCCCTCAGGGGAAGGAACTTAGCAGTGTGCAGGTGAGCTGATGCCGCAAACCCGCTAACCACTGCATGTGCTGTTA
TGCCTTTCCCAGGCTGGACACCTAGCTGGGTGTTCATCATAACTTTCCACAGCTTTAATCCACGCCAAGTTTGTATATAACTGAAATTCA
CTCTTGACACCCTCCACAGTCTTTCCAAGTTGGACTCTTCCTCTCATCAGTACTAGTTGTCAAATTTAAAATGTGACAGTTAAAGAATAT
TCTAGTTTGACAATTAGTAAGCAATGAGTATATCATCAGTACACTAGCTTTTTATTAATCCATGTACACTGTATAGTATCTTGCATCTAT

>5095_5095_10_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000538825_IQCA1_chr2_237247025_ENST00000309507_length(amino acids)=234AA_BP=1
MASWGPLHPRETQAWFFRKALLFLFCLFLFLLFPFPFVLCLFCAASCYRQGTFFTQRSFGIPVLKALFFLFVHWIHAGYRRNKLNCSERF
MNLPPDSLICEHAFNHFDYMSLGEAVSDLRQAADIQGTGEDSSIAFNDLLPQNVSGSIVWSGHQNNFLVNFAERLEFSIEGTPCGPHNQN

--------------------------------------------------------------
>5095_5095_11_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000538825_IQCA1_chr2_237247025_ENST00000409907_length(transcript)=1147nt_BP=97nt
AGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATCTCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGGCCTGGTGGAA
AGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAATCCTGAAACTCCTGAAACCAGATGACCGGATTCTGATTGTGGGGAC
CACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAGTTTACCAGAAAATTATTTTGGTGCCCAGACCAGACTATGCTTCCAG
ATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCCTCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGGTCACTGACGG
CTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCACAGATCAGAGAATCCGGCGGCAAATTCATAAACCTCTCACTGCAGT
TGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAGAGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAACTCCTCTGGG
TAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGGCAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGAAAAAGGCAAA
AAAGAAAAAGTAATGCCTTTCTGAAGAACCATGCTTGAGTCTCTCTGGGATGGAGAGGACCCCAACTCGCCAAAGAAAAGATTCACCATT
GCCCGCCTGAAGAAGCCCTCAGGGGAAGGAACTTAGCAGTGTGCAGGTGAGCTGATGCCGCAAACCCGCTAACCACTGCATGTGCTGTTA
TGCCTTTCCCAGGCTGGACACCTAGCTGGGTGTTCATCATAACTTTCCACAGCTTTAATCCACGCCAAGTTTGTATATAACTGAAATTCA
CTCTTGACACCCTCCACAGTCTTTCCAAGTTGGACTCTTCCTCTCATCAGTACTAGTTGTCAAATTTAAAATGTGACAGTTAAAGAATAT
TCTAGTTTGACAATTAGTAAGCAATGAGTATATCATCAGTACACTAGCTTTTTATTAATCCATGTACACTGTATAGTATCTTGCATCTAT

>5095_5095_11_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000538825_IQCA1_chr2_237247025_ENST00000409907_length(amino acids)=234AA_BP=1
MASWGPLHPRETQAWFFRKALLFLFCLFLFLLFPFPFVLCLFCAASCYRQGTFFTQRSFGIPVLKALFFLFVHWIHAGYRRNKLNCSERF
MNLPPDSLICEHAFNHFDYMSLGEAVSDLRQAADIQGTGEDSSIAFNDLLPQNVSGSIVWSGHQNNFLVNFAERLEFSIEGTPCGPHNQN

--------------------------------------------------------------
>5095_5095_12_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000538825_IQCA1_chr2_237247025_ENST00000431676_length(transcript)=701nt_BP=97nt
AGACGTGTGGAGTCCCAGCAGAGGCCAACCTGTGTCTCTTCATCTCCGTGAGAAAGGTGCCCCCGAAGTGAAAGAGATGGCCTGGTGGAA
AGCCTGGAATGAACCTAAACGCCTGAAAAAACACCTTCCCCAAATCCTGAAACTCCTGAAACCAGATGACCGGATTCTGATTGTGGGGAC
CACACGGCGTCCCTTCGATGCTGAACTCCAATCTTTCTGCAAAGTTTACCAGAAAATTATTTTGGTGCCCAGACCAGACTATGCTTCCAG
ATACGTTCTGTGGAAGCAAATCATTGAACGCAATGGAGGAGTCCTCACCAGTGCCTTGAATGTCAGCTGCCTGGCGAAGGTCACTGACGG
CTTCACCCAAGGACATATAGTCGAAGTGGTTAAAGGCGTGCTCACAGATCAGAGAATCCGGCGGCAAATTCATAAACCTCTCACTGCAGT
TGAGTTTATTACGGCGATAACCAGCATGAATCCAGTGTACAAAGAGGAAGAAGAGAGCTTTAAGAACTGGTATGCCAAAACTCCTCTGGG
TAAAAAACGTGCCTTGGCGATAACAGGAGGCAGCACAGAAAAGGCAAAGGACAAAGGGAAAAGGAAATAAAAGAAAGAGAAAAAGGCAAA

>5095_5095_12_ANXA8L2-IQCA1_ANXA8L2_chr10_47747132_ENST00000538825_IQCA1_chr2_237247025_ENST00000431676_length(amino acids)=177AA_BP=7
MAWWKAWNEPKRLKKHLPQILKLLKPDDRILIVGTTRRPFDAELQSFCKVYQKIILVPRPDYASRYVLWKQIIERNGGVLTSALNVSCLA

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ANXA8L2-IQCA1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for ANXA8L2-IQCA1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for ANXA8L2-IQCA1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source