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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MAML3-CCDC170 (FusionGDB2 ID:51021)

Fusion Gene Summary for MAML3-CCDC170

check button Fusion gene summary
Fusion gene informationFusion gene name: MAML3-CCDC170
Fusion gene ID: 51021
HgeneTgene
Gene symbol

MAML3

CCDC170

Gene ID

55534

80129

Gene namemastermind like transcriptional coactivator 3coiled-coil domain containing 170
SynonymsCAGH3|ERDA3|GDN|MAM-2|MAM2|TNRC3|mam-3C6orf97|bA282P11.1
Cytomap

4q31.1

6q25.1

Type of geneprotein-codingprotein-coding
Descriptionmastermind-like protein 3CAG repeat containing (glia-derived nexin I alpha)expanded repeat domain, CAG/CTG 3polyglutamine richtrinucleotide repeat containing 3coiled-coil domain-containing protein 170
Modification date2020031320200313
UniProtAcc

Q96JK9

Q8IYT3

Ensembl transtripts involved in fusion geneENST00000327122, ENST00000509479, 
ENST00000398940, 		ENST00000544131, 
ENST00000239374, ENST00000367290, 
Fusion gene scores* DoF score22 X 12 X 8=21127 X 13 X 7=637
# samples 2320
** MAII scorelog2(23/2112*10)=-3.19890406841408
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/637*10)=-1.67129337248158
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MAML3 [Title/Abstract] AND CCDC170 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMAML3(140810511)-CCDC170(151869439), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMAML3

GO:0007219

Notch signaling pathway

12370315

HgeneMAML3

GO:0045944

positive regulation of transcription by RNA polymerase II

12370315


check buttonFusion gene breakpoints across MAML3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CCDC170 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-HB-A3YV-01AMAML3chr4

140810511

-CCDC170chr6

151869439

+
ChimerDB4SARCTCGA-X9-A971-01AMAML3chr4

140810511

-CCDC170chr6

151869439

+


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Fusion Gene ORF analysis for MAML3-CCDC170

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000327122ENST00000544131MAML3chr4

140810511

-CCDC170chr6

151869439

+
5CDS-intronENST00000509479ENST00000544131MAML3chr4

140810511

-CCDC170chr6

151869439

+
In-frameENST00000327122ENST00000239374MAML3chr4

140810511

-CCDC170chr6

151869439

+
In-frameENST00000327122ENST00000367290MAML3chr4

140810511

-CCDC170chr6

151869439

+
In-frameENST00000509479ENST00000239374MAML3chr4

140810511

-CCDC170chr6

151869439

+
In-frameENST00000509479ENST00000367290MAML3chr4

140810511

-CCDC170chr6

151869439

+
intron-3CDSENST00000398940ENST00000239374MAML3chr4

140810511

-CCDC170chr6

151869439

+
intron-3CDSENST00000398940ENST00000367290MAML3chr4

140810511

-CCDC170chr6

151869439

+
intron-intronENST00000398940ENST00000544131MAML3chr4

140810511

-CCDC170chr6

151869439

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000509479MAML3chr4140810511-ENST00000239374CCDC170chr6151869439+7542293685744951212
ENST00000509479MAML3chr4140810511-ENST00000367290CCDC170chr6151869439+7563293685745161219
ENST00000327122MAML3chr4140810511-ENST00000239374CCDC170chr6151869439+621716112431701048
ENST00000327122MAML3chr4140810511-ENST00000367290CCDC170chr6151869439+623816112431911055

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000509479ENST00000239374MAML3chr4140810511-CCDC170chr6151869439+0.001619910.99838006
ENST00000509479ENST00000367290MAML3chr4140810511-CCDC170chr6151869439+0.0014045570.9985954
ENST00000327122ENST00000239374MAML3chr4140810511-CCDC170chr6151869439+0.0008066150.9991934
ENST00000327122ENST00000367290MAML3chr4140810511-CCDC170chr6151869439+0.0006939840.99930596

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Fusion Genomic Features for MAML3-CCDC170


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MAML3-CCDC170


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:140810511/chr6:151869439)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MAML3

Q96JK9

CCDC170

Q8IYT3

FUNCTION: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. {ECO:0000269|PubMed:12370315, ECO:0000269|PubMed:12386158}.FUNCTION: Plays a role in Golgi-associated microtubules organization and stabilization. {ECO:0000269|PubMed:28687497}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAML3chr4:140810511chr6:151869439ENST00000509479-25548_5956931139.0Compositional biasNote=Asn-rich
TgeneCCDC170chr4:140810511chr6:151869439ENST00000239374311360_418196716.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC170chr4:140810511chr6:151869439ENST00000239374311478_656196716.0Coiled coilOntology_term=ECO:0000255
TgeneCCDC170chr4:140810511chr6:151869439ENST00000239374311355_591196716.0RegionRequired for binding to microtubules and Golgi apparatus location

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAML3chr4:140810511chr6:151869439ENST00000509479-25467_9686931139.0Compositional biasNote=Gln-rich
TgeneCCDC170chr4:140810511chr6:151869439ENST0000023937431130_286196716.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for MAML3-CCDC170


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>51021_51021_1_MAML3-CCDC170_MAML3_chr4_140810511_ENST00000327122_CCDC170_chr6_151869439_ENST00000239374_length(transcript)=6217nt_BP=1611nt
CTACAAGAGACTGTGAAAAGGAAGTTGGAAGGAGCTCGATCACCACTTAATGGAGACCAGCAGAATGGTGCTTGTGATGGGAATTTTTCT
CCGACTAGCAAACGAATTCGAAAGGACATTTCTGCGGGGATGGAAGCCATCAACAATTTGCCCAGTAACATGCCACTGCCTTCAGCTTCT
CCTCTTCACCAACTTGACCTGAAACCTTCTTTGCCCTTGCAGAACAGTGGAACTCACACTCCTGGGCTTCTAGAAGATCTAAGTAAGAAT
GGTAGGCTCCCTGAGATTAAACTTCCTGTCAACGGTTGCAGTGACCTGGAGGATAGCTTCACCATCTTGCAGAGCAAAGACCTCAAACAA
GAACCTCTCGATGACCCTACTTGCATAGACACATCAGAAACATCTCTTTCAAATCAGAACAAGCTGTTCTCAGACATTAATCTGAATGAT
CAGGAGTGGCAAGAATTAATAGATGAATTGGCCAACACGGTTCCTGAGGATGACATACAGGACCTGTTCAACGAAGACTTTGAAGAGAAG
AAGGAGCCAGAATTCTCGCAGCCAGCAACTGAGACCCCTCTCTCCCAGGAGAGTGCGAGCGTGAAGAGCGACCCCTCTCACTCTCCCTTC
GCACATGTCTCCATGGGATCTCCCCAGGCGAGGCCTTCTTCTTCTGGTCCTCCCTTTTCTACTGTCTCCACGGCCACTAGTTTACCTTCT
GTTGCCAGCACTCCCGCAGCTCCAAACCCTGCAAGCTCACCAGCAAACTGTGCTGTCCAGTCCCCTCAAACTCCAAACCAAGCCCACACT
CCAGGCCAAGCTCCACCTCGGCCTGGAAATGGTTATCTCCTGAATCCGGCAGCAGTGACAGTGGCCGGTTCAGCGTCAGGGCCTGTGGCT
GTGCCCAGCTCTGACATGTCTCCAGCAGAACAGCTCAAACAGATGGCTGCACAGCAGCAACAAAGGGCCAAACTCATGCAGCAGAAACAG
CAACAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCACTCAAATCAGACTTCA
AATTGGTCTCCCTTAGGACCTCCCTCTAGTCCATATGGAGCAGCTTTTACTGCAGAAAAACCAAATAGCCCAATGATGTACCCCCAAGCC
TTTAACAACCAAAACCCTATAGTGCCTCCAATGGCAAACAACCTGCAGAAGACAACAATGAATAACTACCTCCCTCAGAATCACATGAAT
ATGATCAATCAGCAGCCAAATAACTTGGGTACAAACTCCTTAAACAAACAGCACAATATTCTGACTTATGGCAACACTAAACCCCTGACC
CACTTCAATGCAGACCTGAGTCAGAGGATGACACCACCAGTGGCCAACCCCAACAAAAACCCCTTGATGCCGTATATCCAGCAGCAGCAA
CAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAGCCGCCACCTCCACAGCTCCAGGCCCCCAGGGCACACCTGAGCGAAGAC
CAGAAACGCCTGCTTCTCATGAAGCAGAAAGGAGTGATGAATCAGCCCATGGCTTACGCTGCACTTCCATCCCACGGTCAGCTTAGAGAC
CTGCGCAAAGAAAATGAATTCGTGAAAGGACAAATTGTTATTCTTGAAGAGACTATAAATGTCCATGAGATGGAAGCAAAAGCTAGCAGA
GAAACGATCATGAGGCTGGCTTCAGAAGTCAACAGAGAGCAGAAAAAAGCTGCCTCCTGTACTGAAGAGAAAGAGAAGCTGAACCAGGAC
CTGCTCAGTGCTGTAGAAGCAAAAGAAGCTCTTGAAAGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGAT
GCCTCAAAGCAGGAAGTGAGCCTCCTGAAGAAAAGCTCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCA
CAAAGCCAGTACTTCTCATTTAGGGAGAAAATCGCAGCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTG
GAGAAGATTCGAGAAATGGACAGCCGGGAAGAAAGCAGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAG
TTGGGAAAGGAGTCTGGGTTTCACCAGAAAGCTCTCCAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACA
CACCTGGAGGCAGAGCTGGTTTCTGGAGGTGTTTTGCGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTT
TCTCAGAAAATGAAGTTGGACCAGATGGCTGCCGAACTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTT
CGTCTTGAGAGCAATGCAGTCATTGAGAACAAGACCATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGC
AAAGAATTACACATGAGCCTCCTCCGGCAGAAAATAGCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGAC
AACGCGCATCTTACCATCAGGAACTTGCAGAAGAAGGTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTC
AAAGCCAAACTGGCCGACACCAATGAACTGAAGATTAAAACTTTGGAACAGACTAAAGCCATTGAAGATCTAAACAAATCCAGAGACCAA
CTGGAGAAGATGAAGGAGAAAGCTGAGAAAAAGCTCATGTCTGTCAAGTCAGAACTGGATACCACAGAACATGAGGCTAAGGAGAATAAA
GAAAGGGCCAGAAACATGATAGAAGTGGTAACCAGTGAAATGAAGACACTAAAAAAATCTCTGGAAGAAGCAGAAAAGAGAGAAAAGCAG
CTGGCAGACTTCAGGGAGGTGGTGTCGCAGATGCTAGGCTTGAACGTGACCAGCCTTGCTCTTCCTGATTATGAAATCATCAAGTGTCTT
GAAAGATTGGTCCATTCACATCAGCATCACTTTGTTACCTGTGCCTGCCTCAAAGATGTGACTACTGGGCAAGAGAGGCACCCACAAGGC
CATTTACAGCTTCTTCATTGAACACTGTATCTCTTGAGAGAGGTGGCCATAAGACATGGCACACAATTCCCAATTTCACAAATTCCTCAT
GTCTTTGAGATTTGATCAGTTTGTGAATATTTTATGCTTTGATGATATAGTGAGAATGCATCACTTGCAAAAACGATCTCAAAAGTGTCA
GCCTTAGATAAACGTTCAGCATTAAAAACGCCTATTATTTCATTTACTAGCATTTTAGGATCCAGAAGAATTCCACCAGATTGCATGAGT
TAGATTGGGAAATGGGAGTGGGAGATAATATTGGGAGGTATCTATTTTAAGTCAGGGGCTTTACTAGCCGATTTAGTTCTCACAATAACC
ATGTGGAGAAGCTGTGACATTTTTAATTTACAACCTTTCTGGGGCTCAGACATAAAGTTACCTATCCAAGGTTGCAGTTGGGTAGTGGTG
GGACCAGGATGGACAACTCATTGGCCCTGCCTCAAAAGCCATACCTCTTCTCCTGCTATGCAGAATCTGTTTCTCCTGAATCTCTGTGAT
GCTGGTGGGAATTGTTTGCATAGAGGAAGGACAATAACCCTGCCATCGTGAGTTAATGTCCGGGCTGGTCACAGTGGTTCATGCCTGTAA
TCCCAGCACTTTGGGAGTCCAAGGCAGGCATATCATTTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAACATAGTGAGACCCTGTTTCTA
CTAAAAATACAAAAATAAGCCAGGTGTGGTGGTGCATGACTGTAATCCCAACTACTCAGCAGGAGAAGCACTTGAACCCAGGAGACGGAG
GCGGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAAACTACATCTCAGAAAAAAAAAAAAAAAAAAAAAAAA
AAAGTTAATGTCCAAAAATGACAGATTTACAAGTGTAAGCTATATGATTTCTTCAAAAAGCAAAAGCAATATACCTAATTCATTTGGATC
AAACTTACATAGGTCTCAGGTCCTGTAAGAAACTTGCCTGTTCTAACTGTTGCTACCAGATTATATCTGGTGGTAATTGTTAATGTTTCA
GCAGGGCTGGTCTCAGTCCTTTAAAATGGAAAGCTTTATTTGGAGCCCAACCCTATAAGATGAAGAAATCCTATATAGTCTTATTCACCA
ATATATCCAATACACCCACAGCAATGGTACCTTTTTAAGATCAGGATTTTATTATGAATTCCTGTCACTTTCTGTTTTCCATTTAAATTT
CTATTTTACAAATTTTTCAGGGAATCATATTCTTAACTTCACTGAGAAAAATGTGTTACTCTTTTGGACAATTTATCTTATTTCTATCAT
ATAAGATGTATTTTTTTATTGTCCTTAAAAGAAGCTCTAGCATGAAATTAAAGGAAAGGGAAAGAAATAGATCTGGTGCACCCGAACATT
AGGAGAAAATGAAAAATATACAACCAACCGTTCGTGAGTCATCAAAAAGTCAAAGTCAGCCTGGCCAACATGGCAAAACTCCGTCTCTGC
AAAAAATACAAAAATGAGCCCGGTATGTTGGCATATGCCTGTAATCCCAGCTACTCGAGAGGCTGAGACACGAAAATTGCTTGAACCTGG
GAGGCGGAGGTTGCAATGAGCCGAGATCGCGCTACTGCACTCCAGCCTGGGCAACAGAGAGAGACCTTGTCTCAAAAAACAACAACAACA
AAAAGTCAAAGTCATAATAAGCAAATTATTGGCTTCTTTCTTCTAGACTAAAAGAAATTAAAGAGATGAAACAATCAATTGCAAGGGTCA
AAACTAGATTGGATCTTGGTTTGAATGAAAAAAAGCATAAAATATTCTTGCAATAATTGTAAAAATTTGAATGTGGACTAAGTCCTAGAT
TATATTAAAATATTTTTAATTTTTTAAGCTTGACAAATGCACTGATTGTTATACTTTAAATAACTAAAAATCTGAGAATCCACAGTGCTA
CAGACAATAAGTGATAAAATGGGAAAAAATAGTGAAGATCTTCTTTTAGGAAAACTACCAATAAATGTAGAATGGATGATTCCAAAAAAA
AAAAAAAAAAGAAGAAAGAGAGAAAGAAAGAAACAGAAAAACCTAAAAGAAAGCGAATGAATTTGACACCTGTTGGTTGGATGACAGACC
ACACAGAGGGAGAGTGACCAGGCTTTGCTTGTGGAGCGGGCATCCCTGCCTAGCTATCTCCTTCATGTGCAAGGACAGTATAAGTAGTAT
TTTGCATGTGAGTAAACACACCTGCGCAGCCCTGGCTGAGGTCACTAGGCTGGCCAGAGGCAGGACAGGCAGTCTTGAATTTCCTCTAGG
GGAGGCCTGCAGTTTTCCCCACCAACCCCTTTTCACATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTTGGATCGAAAATCACCTTGAGT
GGAGGAAGTGACTTCACTGGGTCTCTGGAGGCTCTCGGAGCTTGAGTGGCTCTGCCCCACCCTGAATCATGCACCCATAAATGCAGTTAT
GGGTGGATGTGGGTGTATGAGAGTGGAGATTGTTTTTGTACATTCTCTTTGTTTTCATTTTCCAAATATAATCTTTAATAAACTTGATTT
AGTTTCTTGGGAAATTTATTTTCTACGCTATTCAAAGATATTTTAAATAATATTTTAAAAACATGAAATTTTTTTTTCATTTTTGATTTG
ATATCATTAATTTTATATCAGGATTCATGTAAGAGACTAAAAATGATCCATAGTGGTTAGTACTGTAATTTCTGTTTATTACATGAAATT
ACATTCCATTTATCCAAATATATGTTTATATAATATTTCCACTGTGTGACTCTAGTGATCTTTAACATACACAGAATGATCTACAGTGAT
CTTTAACATACTCAGAAATATGAAAAATGTTTGAATATGATCTTTAGGGACTTCTAATGAAAAGGGTATATGAAATGGGAACAATAAATT
CTGTACATGTATACAGTCCATATACACATTAAGTGTTTGTCATTTGGACAAATTGAAAACTTTTAATAAAGCCATTTTCTTCTTTGTTAA

>51021_51021_1_MAML3-CCDC170_MAML3_chr4_140810511_ENST00000327122_CCDC170_chr6_151869439_ENST00000239374_length(amino acids)=1048AA_BP=528
MEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKL
PVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQP
ATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRP
GNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPP
SSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQ
RMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQLRDLRKENEFV
KGQIVILEETINVHEMEAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSL
LKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFH
QKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVI
ENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTN
ELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVV

--------------------------------------------------------------
>51021_51021_2_MAML3-CCDC170_MAML3_chr4_140810511_ENST00000327122_CCDC170_chr6_151869439_ENST00000367290_length(transcript)=6238nt_BP=1611nt
CTACAAGAGACTGTGAAAAGGAAGTTGGAAGGAGCTCGATCACCACTTAATGGAGACCAGCAGAATGGTGCTTGTGATGGGAATTTTTCT
CCGACTAGCAAACGAATTCGAAAGGACATTTCTGCGGGGATGGAAGCCATCAACAATTTGCCCAGTAACATGCCACTGCCTTCAGCTTCT
CCTCTTCACCAACTTGACCTGAAACCTTCTTTGCCCTTGCAGAACAGTGGAACTCACACTCCTGGGCTTCTAGAAGATCTAAGTAAGAAT
GGTAGGCTCCCTGAGATTAAACTTCCTGTCAACGGTTGCAGTGACCTGGAGGATAGCTTCACCATCTTGCAGAGCAAAGACCTCAAACAA
GAACCTCTCGATGACCCTACTTGCATAGACACATCAGAAACATCTCTTTCAAATCAGAACAAGCTGTTCTCAGACATTAATCTGAATGAT
CAGGAGTGGCAAGAATTAATAGATGAATTGGCCAACACGGTTCCTGAGGATGACATACAGGACCTGTTCAACGAAGACTTTGAAGAGAAG
AAGGAGCCAGAATTCTCGCAGCCAGCAACTGAGACCCCTCTCTCCCAGGAGAGTGCGAGCGTGAAGAGCGACCCCTCTCACTCTCCCTTC
GCACATGTCTCCATGGGATCTCCCCAGGCGAGGCCTTCTTCTTCTGGTCCTCCCTTTTCTACTGTCTCCACGGCCACTAGTTTACCTTCT
GTTGCCAGCACTCCCGCAGCTCCAAACCCTGCAAGCTCACCAGCAAACTGTGCTGTCCAGTCCCCTCAAACTCCAAACCAAGCCCACACT
CCAGGCCAAGCTCCACCTCGGCCTGGAAATGGTTATCTCCTGAATCCGGCAGCAGTGACAGTGGCCGGTTCAGCGTCAGGGCCTGTGGCT
GTGCCCAGCTCTGACATGTCTCCAGCAGAACAGCTCAAACAGATGGCTGCACAGCAGCAACAAAGGGCCAAACTCATGCAGCAGAAACAG
CAACAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCACTCAAATCAGACTTCA
AATTGGTCTCCCTTAGGACCTCCCTCTAGTCCATATGGAGCAGCTTTTACTGCAGAAAAACCAAATAGCCCAATGATGTACCCCCAAGCC
TTTAACAACCAAAACCCTATAGTGCCTCCAATGGCAAACAACCTGCAGAAGACAACAATGAATAACTACCTCCCTCAGAATCACATGAAT
ATGATCAATCAGCAGCCAAATAACTTGGGTACAAACTCCTTAAACAAACAGCACAATATTCTGACTTATGGCAACACTAAACCCCTGACC
CACTTCAATGCAGACCTGAGTCAGAGGATGACACCACCAGTGGCCAACCCCAACAAAAACCCCTTGATGCCGTATATCCAGCAGCAGCAA
CAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAGCCGCCACCTCCACAGCTCCAGGCCCCCAGGGCACACCTGAGCGAAGAC
CAGAAACGCCTGCTTCTCATGAAGCAGAAAGGAGTGATGAATCAGCCCATGGCTTACGCTGCACTTCCATCCCACGGTCAGCTTAGAGAC
CTGCGCAAAGAAAATGAATTCGTGAAAGGACAAATTGTTATTCTTGAAGAGACTATAAATGTCCATGAGATGGAAGCAAAAGCTAGCAGA
GAAACGATCATGAGGCTGGCTTCAGAAGTCAACAGAGAGCAGAAAAAAGCTGCCTCCTGTACTGAAGAGAAAGAGAAGCTGAACCAGGAC
CTGCTCAGTGCTGTAGAAGCAAAAGAAGCTCTTGAAAGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGAT
GCCTCAAAGCAGGAAGTGAGCCTCCTGAAGAAAAGCTCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCA
CAAAGCCAGTACTTCTCATTTAGGGAGAAAATCGCAGCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTG
GAGAAGATTCGAGAAATGGACAGCCGGGAAGAAAGCAGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAG
TTGGGAAAGGAGTCTGGGTTTCACCAGAAAGCTCTCCAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACA
CACCTGGAGGCAGAGCTGGTTTCTGGAGGTGTTTTGCGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTT
TCTCAGAAAATGAAGTTGGACCAGATGGCTGCCGAACTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTT
CGTCTTGAGAGCAATGCAGTCATTGAGAACAAGACCATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGC
AAAGAATTACACATGAGCCTCCTCCGGCAGAAAATAGCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGAC
AACGCGCATCTTACCATCAGGAACTTGCAGAAGAAGGTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTC
AAAGCCAAACTGGCCGACACCAATGAACTGAAGGCAAGTGCTTGGCTTCATTTTATTAAAACTTTGGAACAGACTAAAGCCATTGAAGAT
CTAAACAAATCCAGAGACCAACTGGAGAAGATGAAGGAGAAAGCTGAGAAAAAGCTCATGTCTGTCAAGTCAGAACTGGATACCACAGAA
CATGAGGCTAAGGAGAATAAAGAAAGGGCCAGAAACATGATAGAAGTGGTAACCAGTGAAATGAAGACACTAAAAAAATCTCTGGAAGAA
GCAGAAAAGAGAGAAAAGCAGCTGGCAGACTTCAGGGAGGTGGTGTCGCAGATGCTAGGCTTGAACGTGACCAGCCTTGCTCTTCCTGAT
TATGAAATCATCAAGTGTCTTGAAAGATTGGTCCATTCACATCAGCATCACTTTGTTACCTGTGCCTGCCTCAAAGATGTGACTACTGGG
CAAGAGAGGCACCCACAAGGCCATTTACAGCTTCTTCATTGAACACTGTATCTCTTGAGAGAGGTGGCCATAAGACATGGCACACAATTC
CCAATTTCACAAATTCCTCATGTCTTTGAGATTTGATCAGTTTGTGAATATTTTATGCTTTGATGATATAGTGAGAATGCATCACTTGCA
AAAACGATCTCAAAAGTGTCAGCCTTAGATAAACGTTCAGCATTAAAAACGCCTATTATTTCATTTACTAGCATTTTAGGATCCAGAAGA
ATTCCACCAGATTGCATGAGTTAGATTGGGAAATGGGAGTGGGAGATAATATTGGGAGGTATCTATTTTAAGTCAGGGGCTTTACTAGCC
GATTTAGTTCTCACAATAACCATGTGGAGAAGCTGTGACATTTTTAATTTACAACCTTTCTGGGGCTCAGACATAAAGTTACCTATCCAA
GGTTGCAGTTGGGTAGTGGTGGGACCAGGATGGACAACTCATTGGCCCTGCCTCAAAAGCCATACCTCTTCTCCTGCTATGCAGAATCTG
TTTCTCCTGAATCTCTGTGATGCTGGTGGGAATTGTTTGCATAGAGGAAGGACAATAACCCTGCCATCGTGAGTTAATGTCCGGGCTGGT
CACAGTGGTTCATGCCTGTAATCCCAGCACTTTGGGAGTCCAAGGCAGGCATATCATTTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAA
CATAGTGAGACCCTGTTTCTACTAAAAATACAAAAATAAGCCAGGTGTGGTGGTGCATGACTGTAATCCCAACTACTCAGCAGGAGAAGC
ACTTGAACCCAGGAGACGGAGGCGGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAAACTACATCTCAGAAA
AAAAAAAAAAAAAAAAAAAAAAAAGTTAATGTCCAAAAATGACAGATTTACAAGTGTAAGCTATATGATTTCTTCAAAAAGCAAAAGCAA
TATACCTAATTCATTTGGATCAAACTTACATAGGTCTCAGGTCCTGTAAGAAACTTGCCTGTTCTAACTGTTGCTACCAGATTATATCTG
GTGGTAATTGTTAATGTTTCAGCAGGGCTGGTCTCAGTCCTTTAAAATGGAAAGCTTTATTTGGAGCCCAACCCTATAAGATGAAGAAAT
CCTATATAGTCTTATTCACCAATATATCCAATACACCCACAGCAATGGTACCTTTTTAAGATCAGGATTTTATTATGAATTCCTGTCACT
TTCTGTTTTCCATTTAAATTTCTATTTTACAAATTTTTCAGGGAATCATATTCTTAACTTCACTGAGAAAAATGTGTTACTCTTTTGGAC
AATTTATCTTATTTCTATCATATAAGATGTATTTTTTTATTGTCCTTAAAAGAAGCTCTAGCATGAAATTAAAGGAAAGGGAAAGAAATA
GATCTGGTGCACCCGAACATTAGGAGAAAATGAAAAATATACAACCAACCGTTCGTGAGTCATCAAAAAGTCAAAGTCAGCCTGGCCAAC
ATGGCAAAACTCCGTCTCTGCAAAAAATACAAAAATGAGCCCGGTATGTTGGCATATGCCTGTAATCCCAGCTACTCGAGAGGCTGAGAC
ACGAAAATTGCTTGAACCTGGGAGGCGGAGGTTGCAATGAGCCGAGATCGCGCTACTGCACTCCAGCCTGGGCAACAGAGAGAGACCTTG
TCTCAAAAAACAACAACAACAAAAAGTCAAAGTCATAATAAGCAAATTATTGGCTTCTTTCTTCTAGACTAAAAGAAATTAAAGAGATGA
AACAATCAATTGCAAGGGTCAAAACTAGATTGGATCTTGGTTTGAATGAAAAAAAGCATAAAATATTCTTGCAATAATTGTAAAAATTTG
AATGTGGACTAAGTCCTAGATTATATTAAAATATTTTTAATTTTTTAAGCTTGACAAATGCACTGATTGTTATACTTTAAATAACTAAAA
ATCTGAGAATCCACAGTGCTACAGACAATAAGTGATAAAATGGGAAAAAATAGTGAAGATCTTCTTTTAGGAAAACTACCAATAAATGTA
GAATGGATGATTCCAAAAAAAAAAAAAAAAAGAAGAAAGAGAGAAAGAAAGAAACAGAAAAACCTAAAAGAAAGCGAATGAATTTGACAC
CTGTTGGTTGGATGACAGACCACACAGAGGGAGAGTGACCAGGCTTTGCTTGTGGAGCGGGCATCCCTGCCTAGCTATCTCCTTCATGTG
CAAGGACAGTATAAGTAGTATTTTGCATGTGAGTAAACACACCTGCGCAGCCCTGGCTGAGGTCACTAGGCTGGCCAGAGGCAGGACAGG
CAGTCTTGAATTTCCTCTAGGGGAGGCCTGCAGTTTTCCCCACCAACCCCTTTTCACATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTT
GGATCGAAAATCACCTTGAGTGGAGGAAGTGACTTCACTGGGTCTCTGGAGGCTCTCGGAGCTTGAGTGGCTCTGCCCCACCCTGAATCA
TGCACCCATAAATGCAGTTATGGGTGGATGTGGGTGTATGAGAGTGGAGATTGTTTTTGTACATTCTCTTTGTTTTCATTTTCCAAATAT
AATCTTTAATAAACTTGATTTAGTTTCTTGGGAAATTTATTTTCTACGCTATTCAAAGATATTTTAAATAATATTTTAAAAACATGAAAT
TTTTTTTTCATTTTTGATTTGATATCATTAATTTTATATCAGGATTCATGTAAGAGACTAAAAATGATCCATAGTGGTTAGTACTGTAAT
TTCTGTTTATTACATGAAATTACATTCCATTTATCCAAATATATGTTTATATAATATTTCCACTGTGTGACTCTAGTGATCTTTAACATA
CACAGAATGATCTACAGTGATCTTTAACATACTCAGAAATATGAAAAATGTTTGAATATGATCTTTAGGGACTTCTAATGAAAAGGGTAT
ATGAAATGGGAACAATAAATTCTGTACATGTATACAGTCCATATACACATTAAGTGTTTGTCATTTGGACAAATTGAAAACTTTTAATAA

>51021_51021_2_MAML3-CCDC170_MAML3_chr4_140810511_ENST00000327122_CCDC170_chr6_151869439_ENST00000367290_length(amino acids)=1055AA_BP=528
MEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKL
PVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQP
ATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRP
GNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPP
SSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQ
RMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQLRDLRKENEFV
KGQIVILEETINVHEMEAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSL
LKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFH
QKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVI
ENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTN
ELKASAWLHFIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQL

--------------------------------------------------------------
>51021_51021_3_MAML3-CCDC170_MAML3_chr4_140810511_ENST00000509479_CCDC170_chr6_151869439_ENST00000239374_length(transcript)=7542nt_BP=2936nt
ACTCCGCTGGCATGGAGGAGGAGGAGGAGGTGGAGGAGCGAGAGGAGGAGGAGGAGGCGGCGGCGGCGGCGGCGGCGAGCAGTTGATCAT
TGTGATGGTGGCAGGAGCAGCGGCGGCAGCGGCAGCCCAGCCGAGCGTTAGGTGCTGCTCTCTGCGCGGCGTTTTGCAAAGGACTTCACC
GATCTACTTTTGCAGTCGCCTCGGACTGTCCATGTGTTTACTTCCCCCAGCCCGAGGATTCGATATCTAGGTTCCTGTGAAATGCAACTG
AGCAGCCAAAGTACTTTGAGAACACGGGGCGGCATAAACACCAAAACTTTTTTGTGGAAGGAAAATGCAATAAGCAAGCTTGCCGTTTTC
CGATGCGGTGTGGAGTGAGTGTGTGTCGCGCGTGTCCGCACTGGAGGCATATGCTTGTGTGTGTACATGGGGTGTGTTTTTCGGTATGTA
GGGAGAAAATGCTTGCCAACCACCGGAAATCTCCTGGAATTTATTAGAAAATAATGGATTATAAAAAGAAGGCAAGCAAGGAGCGGATCT
CCCCTTGAGTTGCAACCCGATTTGCTGCTGGCTCAGTTTGTTGTGATTCTTTTTGTTGATAGGTGTCTGATGGTATTCCGATAACGTTCC
CCCCTTTTCTTCCCCTTGAGCTTTTACAGTTTAAAAAAAGGAAACAAAAACCACCCCAAAATCTCCCCCCCCGTTTTTTTCGCCCCGTCG
GGATCGCCGTTTCCATCCATGTGCTTGCGTCTCCCCCGCGTTCCACTTAAACTATTTTAATCCTTGGACCCAAGGAGGAGGCTGATAGGG
GGGTGGATAAAAAAAGTTCTTCCAAAATAGTGTGCCCGGGGAGCAGGATGGGGGATTTCGCAGCCCCCGCTGCTGCCGCGAATGGCAGTA
GTATTTGCATCAACAGTAGCCTGAACAGCAGCCTCGGCGGGGCCGGGATCGGTGTGAATAATACTCCCAATAGTACTCCCGCTGCTCCGA
GTAGCAATCACCCGGCAGCCGGTGGATGCGGCGGCTCCGGGGGCCCCGGCGGCGGTTCGGCGGCCGTTCCCAAGCACAGCACCGTGGTGG
AGCGGCTCCGCCAGCGCATCGAGGGCTGCCGTCGGCACCACGTCAACTGCGAGAACAGGTACCAGCAGGCTCAGGTGGAGCAGCTGGAGC
TGGAGCGCCGGGACACCGTGAGCCTCTACCAGCGGACCCTGGAGCAGAGGGCCAAGAAATCGGGCGCCGGCACCGGCAAACAGCAGCACC
CGAGCAAACCCCAGCAAGATGCGGAGGCTGCCTCGGCGGAGCAGAGGAACCACACGCTGATCATGCTACAAGAGACTGTGAAAAGGAAGT
TGGAAGGAGCTCGATCACCACTTAATGGAGACCAGCAGAATGGTGCTTGTGATGGGAATTTTTCTCCGACTAGCAAACGAATTCGAAAGG
ACATTTCTGCGGGGATGGAAGCCATCAACAATTTGCCCAGTAACATGCCACTGCCTTCAGCTTCTCCTCTTCACCAACTTGACCTGAAAC
CTTCTTTGCCCTTGCAGAACAGTGGAACTCACACTCCTGGGCTTCTAGAAGATCTAAGTAAGAATGGTAGGCTCCCTGAGATTAAACTTC
CTGTCAACGGTTGCAGTGACCTGGAGGATAGCTTCACCATCTTGCAGAGCAAAGACCTCAAACAAGAACCTCTCGATGACCCTACTTGCA
TAGACACATCAGAAACATCTCTTTCAAATCAGAACAAGCTGTTCTCAGACATTAATCTGAATGATCAGGAGTGGCAAGAATTAATAGATG
AATTGGCCAACACGGTTCCTGAGGATGACATACAGGACCTGTTCAACGAAGACTTTGAAGAGAAGAAGGAGCCAGAATTCTCGCAGCCAG
CAACTGAGACCCCTCTCTCCCAGGAGAGTGCGAGCGTGAAGAGCGACCCCTCTCACTCTCCCTTCGCACATGTCTCCATGGGATCTCCCC
AGGCGAGGCCTTCTTCTTCTGGTCCTCCCTTTTCTACTGTCTCCACGGCCACTAGTTTACCTTCTGTTGCCAGCACTCCCGCAGCTCCAA
ACCCTGCAAGCTCACCAGCAAACTGTGCTGTCCAGTCCCCTCAAACTCCAAACCAAGCCCACACTCCAGGCCAAGCTCCACCTCGGCCTG
GAAATGGTTATCTCCTGAATCCGGCAGCAGTGACAGTGGCCGGTTCAGCGTCAGGGCCTGTGGCTGTGCCCAGCTCTGACATGTCTCCAG
CAGAACAGCTCAAACAGATGGCTGCACAGCAGCAACAAAGGGCCAAACTCATGCAGCAGAAACAGCAACAGCAACAGCAGCAGCAGCAGC
AGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCACTCAAATCAGACTTCAAATTGGTCTCCCTTAGGACCTCCCT
CTAGTCCATATGGAGCAGCTTTTACTGCAGAAAAACCAAATAGCCCAATGATGTACCCCCAAGCCTTTAACAACCAAAACCCTATAGTGC
CTCCAATGGCAAACAACCTGCAGAAGACAACAATGAATAACTACCTCCCTCAGAATCACATGAATATGATCAATCAGCAGCCAAATAACT
TGGGTACAAACTCCTTAAACAAACAGCACAATATTCTGACTTATGGCAACACTAAACCCCTGACCCACTTCAATGCAGACCTGAGTCAGA
GGATGACACCACCAGTGGCCAACCCCAACAAAAACCCCTTGATGCCGTATATCCAGCAGCAGCAACAGCAGCAGCAACAGCAACAGCAGC
AGCAGCAGCAGCAGCAGCCGCCACCTCCACAGCTCCAGGCCCCCAGGGCACACCTGAGCGAAGACCAGAAACGCCTGCTTCTCATGAAGC
AGAAAGGAGTGATGAATCAGCCCATGGCTTACGCTGCACTTCCATCCCACGGTCAGCTTAGAGACCTGCGCAAAGAAAATGAATTCGTGA
AAGGACAAATTGTTATTCTTGAAGAGACTATAAATGTCCATGAGATGGAAGCAAAAGCTAGCAGAGAAACGATCATGAGGCTGGCTTCAG
AAGTCAACAGAGAGCAGAAAAAAGCTGCCTCCTGTACTGAAGAGAAAGAGAAGCTGAACCAGGACCTGCTCAGTGCTGTAGAAGCAAAAG
AAGCTCTTGAAAGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGATGCCTCAAAGCAGGAAGTGAGCCTCC
TGAAGAAAAGCTCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCACAAAGCCAGTACTTCTCATTTAGGG
AGAAAATCGCAGCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTGGAGAAGATTCGAGAAATGGACAGCC
GGGAAGAAAGCAGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAGTTGGGAAAGGAGTCTGGGTTTCACC
AGAAAGCTCTCCAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACACACCTGGAGGCAGAGCTGGTTTCTG
GAGGTGTTTTGCGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTTTCTCAGAAAATGAAGTTGGACCAGA
TGGCTGCCGAACTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTTCGTCTTGAGAGCAATGCAGTCATTG
AGAACAAGACCATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGCAAAGAATTACACATGAGCCTCCTCC
GGCAGAAAATAGCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGACAACGCGCATCTTACCATCAGGAACT
TGCAGAAGAAGGTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTCAAAGCCAAACTGGCCGACACCAATG
AACTGAAGATTAAAACTTTGGAACAGACTAAAGCCATTGAAGATCTAAACAAATCCAGAGACCAACTGGAGAAGATGAAGGAGAAAGCTG
AGAAAAAGCTCATGTCTGTCAAGTCAGAACTGGATACCACAGAACATGAGGCTAAGGAGAATAAAGAAAGGGCCAGAAACATGATAGAAG
TGGTAACCAGTGAAATGAAGACACTAAAAAAATCTCTGGAAGAAGCAGAAAAGAGAGAAAAGCAGCTGGCAGACTTCAGGGAGGTGGTGT
CGCAGATGCTAGGCTTGAACGTGACCAGCCTTGCTCTTCCTGATTATGAAATCATCAAGTGTCTTGAAAGATTGGTCCATTCACATCAGC
ATCACTTTGTTACCTGTGCCTGCCTCAAAGATGTGACTACTGGGCAAGAGAGGCACCCACAAGGCCATTTACAGCTTCTTCATTGAACAC
TGTATCTCTTGAGAGAGGTGGCCATAAGACATGGCACACAATTCCCAATTTCACAAATTCCTCATGTCTTTGAGATTTGATCAGTTTGTG
AATATTTTATGCTTTGATGATATAGTGAGAATGCATCACTTGCAAAAACGATCTCAAAAGTGTCAGCCTTAGATAAACGTTCAGCATTAA
AAACGCCTATTATTTCATTTACTAGCATTTTAGGATCCAGAAGAATTCCACCAGATTGCATGAGTTAGATTGGGAAATGGGAGTGGGAGA
TAATATTGGGAGGTATCTATTTTAAGTCAGGGGCTTTACTAGCCGATTTAGTTCTCACAATAACCATGTGGAGAAGCTGTGACATTTTTA
ATTTACAACCTTTCTGGGGCTCAGACATAAAGTTACCTATCCAAGGTTGCAGTTGGGTAGTGGTGGGACCAGGATGGACAACTCATTGGC
CCTGCCTCAAAAGCCATACCTCTTCTCCTGCTATGCAGAATCTGTTTCTCCTGAATCTCTGTGATGCTGGTGGGAATTGTTTGCATAGAG
GAAGGACAATAACCCTGCCATCGTGAGTTAATGTCCGGGCTGGTCACAGTGGTTCATGCCTGTAATCCCAGCACTTTGGGAGTCCAAGGC
AGGCATATCATTTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAACATAGTGAGACCCTGTTTCTACTAAAAATACAAAAATAAGCCAGGT
GTGGTGGTGCATGACTGTAATCCCAACTACTCAGCAGGAGAAGCACTTGAACCCAGGAGACGGAGGCGGCAGTGAGCCAAGATTGTGCCA
CTGCACTCCAGCCTGGGCGACAGAGTGAAACTACATCTCAGAAAAAAAAAAAAAAAAAAAAAAAAAAAGTTAATGTCCAAAAATGACAGA
TTTACAAGTGTAAGCTATATGATTTCTTCAAAAAGCAAAAGCAATATACCTAATTCATTTGGATCAAACTTACATAGGTCTCAGGTCCTG
TAAGAAACTTGCCTGTTCTAACTGTTGCTACCAGATTATATCTGGTGGTAATTGTTAATGTTTCAGCAGGGCTGGTCTCAGTCCTTTAAA
ATGGAAAGCTTTATTTGGAGCCCAACCCTATAAGATGAAGAAATCCTATATAGTCTTATTCACCAATATATCCAATACACCCACAGCAAT
GGTACCTTTTTAAGATCAGGATTTTATTATGAATTCCTGTCACTTTCTGTTTTCCATTTAAATTTCTATTTTACAAATTTTTCAGGGAAT
CATATTCTTAACTTCACTGAGAAAAATGTGTTACTCTTTTGGACAATTTATCTTATTTCTATCATATAAGATGTATTTTTTTATTGTCCT
TAAAAGAAGCTCTAGCATGAAATTAAAGGAAAGGGAAAGAAATAGATCTGGTGCACCCGAACATTAGGAGAAAATGAAAAATATACAACC
AACCGTTCGTGAGTCATCAAAAAGTCAAAGTCAGCCTGGCCAACATGGCAAAACTCCGTCTCTGCAAAAAATACAAAAATGAGCCCGGTA
TGTTGGCATATGCCTGTAATCCCAGCTACTCGAGAGGCTGAGACACGAAAATTGCTTGAACCTGGGAGGCGGAGGTTGCAATGAGCCGAG
ATCGCGCTACTGCACTCCAGCCTGGGCAACAGAGAGAGACCTTGTCTCAAAAAACAACAACAACAAAAAGTCAAAGTCATAATAAGCAAA
TTATTGGCTTCTTTCTTCTAGACTAAAAGAAATTAAAGAGATGAAACAATCAATTGCAAGGGTCAAAACTAGATTGGATCTTGGTTTGAA
TGAAAAAAAGCATAAAATATTCTTGCAATAATTGTAAAAATTTGAATGTGGACTAAGTCCTAGATTATATTAAAATATTTTTAATTTTTT
AAGCTTGACAAATGCACTGATTGTTATACTTTAAATAACTAAAAATCTGAGAATCCACAGTGCTACAGACAATAAGTGATAAAATGGGAA
AAAATAGTGAAGATCTTCTTTTAGGAAAACTACCAATAAATGTAGAATGGATGATTCCAAAAAAAAAAAAAAAAAGAAGAAAGAGAGAAA
GAAAGAAACAGAAAAACCTAAAAGAAAGCGAATGAATTTGACACCTGTTGGTTGGATGACAGACCACACAGAGGGAGAGTGACCAGGCTT
TGCTTGTGGAGCGGGCATCCCTGCCTAGCTATCTCCTTCATGTGCAAGGACAGTATAAGTAGTATTTTGCATGTGAGTAAACACACCTGC
GCAGCCCTGGCTGAGGTCACTAGGCTGGCCAGAGGCAGGACAGGCAGTCTTGAATTTCCTCTAGGGGAGGCCTGCAGTTTTCCCCACCAA
CCCCTTTTCACATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTTGGATCGAAAATCACCTTGAGTGGAGGAAGTGACTTCACTGGGTCTC
TGGAGGCTCTCGGAGCTTGAGTGGCTCTGCCCCACCCTGAATCATGCACCCATAAATGCAGTTATGGGTGGATGTGGGTGTATGAGAGTG
GAGATTGTTTTTGTACATTCTCTTTGTTTTCATTTTCCAAATATAATCTTTAATAAACTTGATTTAGTTTCTTGGGAAATTTATTTTCTA
CGCTATTCAAAGATATTTTAAATAATATTTTAAAAACATGAAATTTTTTTTTCATTTTTGATTTGATATCATTAATTTTATATCAGGATT
CATGTAAGAGACTAAAAATGATCCATAGTGGTTAGTACTGTAATTTCTGTTTATTACATGAAATTACATTCCATTTATCCAAATATATGT
TTATATAATATTTCCACTGTGTGACTCTAGTGATCTTTAACATACACAGAATGATCTACAGTGATCTTTAACATACTCAGAAATATGAAA
AATGTTTGAATATGATCTTTAGGGACTTCTAATGAAAAGGGTATATGAAATGGGAACAATAAATTCTGTACATGTATACAGTCCATATAC

>51021_51021_3_MAML3-CCDC170_MAML3_chr4_140810511_ENST00000509479_CCDC170_chr6_151869439_ENST00000239374_length(amino acids)=1212AA_BP=692
MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVN
CENRYQQAQVEQLELERRDTVSLYQRTLEQRAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGA
CDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQ
SKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKSD
PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGS
ASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSP
MMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMP
YIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQLRDLRKENEFVKGQIVILEETINVHEM
EAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQ
DAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAENMLET
LQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQ
KERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTKAIEDL
NKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSLALPDY

--------------------------------------------------------------
>51021_51021_4_MAML3-CCDC170_MAML3_chr4_140810511_ENST00000509479_CCDC170_chr6_151869439_ENST00000367290_length(transcript)=7563nt_BP=2936nt
ACTCCGCTGGCATGGAGGAGGAGGAGGAGGTGGAGGAGCGAGAGGAGGAGGAGGAGGCGGCGGCGGCGGCGGCGGCGAGCAGTTGATCAT
TGTGATGGTGGCAGGAGCAGCGGCGGCAGCGGCAGCCCAGCCGAGCGTTAGGTGCTGCTCTCTGCGCGGCGTTTTGCAAAGGACTTCACC
GATCTACTTTTGCAGTCGCCTCGGACTGTCCATGTGTTTACTTCCCCCAGCCCGAGGATTCGATATCTAGGTTCCTGTGAAATGCAACTG
AGCAGCCAAAGTACTTTGAGAACACGGGGCGGCATAAACACCAAAACTTTTTTGTGGAAGGAAAATGCAATAAGCAAGCTTGCCGTTTTC
CGATGCGGTGTGGAGTGAGTGTGTGTCGCGCGTGTCCGCACTGGAGGCATATGCTTGTGTGTGTACATGGGGTGTGTTTTTCGGTATGTA
GGGAGAAAATGCTTGCCAACCACCGGAAATCTCCTGGAATTTATTAGAAAATAATGGATTATAAAAAGAAGGCAAGCAAGGAGCGGATCT
CCCCTTGAGTTGCAACCCGATTTGCTGCTGGCTCAGTTTGTTGTGATTCTTTTTGTTGATAGGTGTCTGATGGTATTCCGATAACGTTCC
CCCCTTTTCTTCCCCTTGAGCTTTTACAGTTTAAAAAAAGGAAACAAAAACCACCCCAAAATCTCCCCCCCCGTTTTTTTCGCCCCGTCG
GGATCGCCGTTTCCATCCATGTGCTTGCGTCTCCCCCGCGTTCCACTTAAACTATTTTAATCCTTGGACCCAAGGAGGAGGCTGATAGGG
GGGTGGATAAAAAAAGTTCTTCCAAAATAGTGTGCCCGGGGAGCAGGATGGGGGATTTCGCAGCCCCCGCTGCTGCCGCGAATGGCAGTA
GTATTTGCATCAACAGTAGCCTGAACAGCAGCCTCGGCGGGGCCGGGATCGGTGTGAATAATACTCCCAATAGTACTCCCGCTGCTCCGA
GTAGCAATCACCCGGCAGCCGGTGGATGCGGCGGCTCCGGGGGCCCCGGCGGCGGTTCGGCGGCCGTTCCCAAGCACAGCACCGTGGTGG
AGCGGCTCCGCCAGCGCATCGAGGGCTGCCGTCGGCACCACGTCAACTGCGAGAACAGGTACCAGCAGGCTCAGGTGGAGCAGCTGGAGC
TGGAGCGCCGGGACACCGTGAGCCTCTACCAGCGGACCCTGGAGCAGAGGGCCAAGAAATCGGGCGCCGGCACCGGCAAACAGCAGCACC
CGAGCAAACCCCAGCAAGATGCGGAGGCTGCCTCGGCGGAGCAGAGGAACCACACGCTGATCATGCTACAAGAGACTGTGAAAAGGAAGT
TGGAAGGAGCTCGATCACCACTTAATGGAGACCAGCAGAATGGTGCTTGTGATGGGAATTTTTCTCCGACTAGCAAACGAATTCGAAAGG
ACATTTCTGCGGGGATGGAAGCCATCAACAATTTGCCCAGTAACATGCCACTGCCTTCAGCTTCTCCTCTTCACCAACTTGACCTGAAAC
CTTCTTTGCCCTTGCAGAACAGTGGAACTCACACTCCTGGGCTTCTAGAAGATCTAAGTAAGAATGGTAGGCTCCCTGAGATTAAACTTC
CTGTCAACGGTTGCAGTGACCTGGAGGATAGCTTCACCATCTTGCAGAGCAAAGACCTCAAACAAGAACCTCTCGATGACCCTACTTGCA
TAGACACATCAGAAACATCTCTTTCAAATCAGAACAAGCTGTTCTCAGACATTAATCTGAATGATCAGGAGTGGCAAGAATTAATAGATG
AATTGGCCAACACGGTTCCTGAGGATGACATACAGGACCTGTTCAACGAAGACTTTGAAGAGAAGAAGGAGCCAGAATTCTCGCAGCCAG
CAACTGAGACCCCTCTCTCCCAGGAGAGTGCGAGCGTGAAGAGCGACCCCTCTCACTCTCCCTTCGCACATGTCTCCATGGGATCTCCCC
AGGCGAGGCCTTCTTCTTCTGGTCCTCCCTTTTCTACTGTCTCCACGGCCACTAGTTTACCTTCTGTTGCCAGCACTCCCGCAGCTCCAA
ACCCTGCAAGCTCACCAGCAAACTGTGCTGTCCAGTCCCCTCAAACTCCAAACCAAGCCCACACTCCAGGCCAAGCTCCACCTCGGCCTG
GAAATGGTTATCTCCTGAATCCGGCAGCAGTGACAGTGGCCGGTTCAGCGTCAGGGCCTGTGGCTGTGCCCAGCTCTGACATGTCTCCAG
CAGAACAGCTCAAACAGATGGCTGCACAGCAGCAACAAAGGGCCAAACTCATGCAGCAGAAACAGCAACAGCAACAGCAGCAGCAGCAGC
AGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCACTCAAATCAGACTTCAAATTGGTCTCCCTTAGGACCTCCCT
CTAGTCCATATGGAGCAGCTTTTACTGCAGAAAAACCAAATAGCCCAATGATGTACCCCCAAGCCTTTAACAACCAAAACCCTATAGTGC
CTCCAATGGCAAACAACCTGCAGAAGACAACAATGAATAACTACCTCCCTCAGAATCACATGAATATGATCAATCAGCAGCCAAATAACT
TGGGTACAAACTCCTTAAACAAACAGCACAATATTCTGACTTATGGCAACACTAAACCCCTGACCCACTTCAATGCAGACCTGAGTCAGA
GGATGACACCACCAGTGGCCAACCCCAACAAAAACCCCTTGATGCCGTATATCCAGCAGCAGCAACAGCAGCAGCAACAGCAACAGCAGC
AGCAGCAGCAGCAGCAGCCGCCACCTCCACAGCTCCAGGCCCCCAGGGCACACCTGAGCGAAGACCAGAAACGCCTGCTTCTCATGAAGC
AGAAAGGAGTGATGAATCAGCCCATGGCTTACGCTGCACTTCCATCCCACGGTCAGCTTAGAGACCTGCGCAAAGAAAATGAATTCGTGA
AAGGACAAATTGTTATTCTTGAAGAGACTATAAATGTCCATGAGATGGAAGCAAAAGCTAGCAGAGAAACGATCATGAGGCTGGCTTCAG
AAGTCAACAGAGAGCAGAAAAAAGCTGCCTCCTGTACTGAAGAGAAAGAGAAGCTGAACCAGGACCTGCTCAGTGCTGTAGAAGCAAAAG
AAGCTCTTGAAAGGGAAGTTAAGATCTTCCAAGAAAGGCTGCTTGCTGGCCAGCAGGTCTGGGATGCCTCAAAGCAGGAAGTGAGCCTCC
TGAAGAAAAGCTCTTCTGAGTTGGAGAAGAGTTTGAAGGCCAGTCAGGATGCAGTCACAACCTCACAAAGCCAGTACTTCTCATTTAGGG
AGAAAATCGCAGCCCTCCTTAGGGGCAGATTGAGCATGACTGGGTCCACTGAGGACACCATTTTGGAGAAGATTCGAGAAATGGACAGCC
GGGAAGAAAGCAGGGACCGGATGGTCTCCCAGCTTGAAGCCCAAATATCTGAGCTTGTTGAACAGTTGGGAAAGGAGTCTGGGTTTCACC
AGAAAGCTCTCCAGAGGGCCCAGAAAGCAGAGAATATGTTGGAGACTCTTCAGGGTCAGCTGACACACCTGGAGGCAGAGCTGGTTTCTG
GAGGTGTTTTGCGAGACAACTTGAATTTTGAGAAACAAAAATATCTTAAATTTCTGGATCAGCTTTCTCAGAAAATGAAGTTGGACCAGA
TGGCTGCCGAACTTGGCTTTGACATGCGGCTGGACGTGGTTTTAGCTCGAACAGAGCAGCTGGTTCGTCTTGAGAGCAATGCAGTCATTG
AGAACAAGACCATTGCCCACAATTTGCAGAGAAAGCTAAAGACACAGAAAGAGAGACTGGAGAGCAAAGAATTACACATGAGCCTCCTCC
GGCAGAAAATAGCCCAGCTGGAGGAGGAGAAGCAGGCACGCACGGCCTTGGTGGTTGAGAGGGACAACGCGCATCTTACCATCAGGAACT
TGCAGAAGAAGGTGGAGAGGCTGCAGAAAGAGCTGAACACGTGTCGAGACTTGCACACCGAGCTCAAAGCCAAACTGGCCGACACCAATG
AACTGAAGGCAAGTGCTTGGCTTCATTTTATTAAAACTTTGGAACAGACTAAAGCCATTGAAGATCTAAACAAATCCAGAGACCAACTGG
AGAAGATGAAGGAGAAAGCTGAGAAAAAGCTCATGTCTGTCAAGTCAGAACTGGATACCACAGAACATGAGGCTAAGGAGAATAAAGAAA
GGGCCAGAAACATGATAGAAGTGGTAACCAGTGAAATGAAGACACTAAAAAAATCTCTGGAAGAAGCAGAAAAGAGAGAAAAGCAGCTGG
CAGACTTCAGGGAGGTGGTGTCGCAGATGCTAGGCTTGAACGTGACCAGCCTTGCTCTTCCTGATTATGAAATCATCAAGTGTCTTGAAA
GATTGGTCCATTCACATCAGCATCACTTTGTTACCTGTGCCTGCCTCAAAGATGTGACTACTGGGCAAGAGAGGCACCCACAAGGCCATT
TACAGCTTCTTCATTGAACACTGTATCTCTTGAGAGAGGTGGCCATAAGACATGGCACACAATTCCCAATTTCACAAATTCCTCATGTCT
TTGAGATTTGATCAGTTTGTGAATATTTTATGCTTTGATGATATAGTGAGAATGCATCACTTGCAAAAACGATCTCAAAAGTGTCAGCCT
TAGATAAACGTTCAGCATTAAAAACGCCTATTATTTCATTTACTAGCATTTTAGGATCCAGAAGAATTCCACCAGATTGCATGAGTTAGA
TTGGGAAATGGGAGTGGGAGATAATATTGGGAGGTATCTATTTTAAGTCAGGGGCTTTACTAGCCGATTTAGTTCTCACAATAACCATGT
GGAGAAGCTGTGACATTTTTAATTTACAACCTTTCTGGGGCTCAGACATAAAGTTACCTATCCAAGGTTGCAGTTGGGTAGTGGTGGGAC
CAGGATGGACAACTCATTGGCCCTGCCTCAAAAGCCATACCTCTTCTCCTGCTATGCAGAATCTGTTTCTCCTGAATCTCTGTGATGCTG
GTGGGAATTGTTTGCATAGAGGAAGGACAATAACCCTGCCATCGTGAGTTAATGTCCGGGCTGGTCACAGTGGTTCATGCCTGTAATCCC
AGCACTTTGGGAGTCCAAGGCAGGCATATCATTTGAGGTCAGGAGTTTAAGACCAGCCTGGCTAACATAGTGAGACCCTGTTTCTACTAA
AAATACAAAAATAAGCCAGGTGTGGTGGTGCATGACTGTAATCCCAACTACTCAGCAGGAGAAGCACTTGAACCCAGGAGACGGAGGCGG
CAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAAACTACATCTCAGAAAAAAAAAAAAAAAAAAAAAAAAAAAG
TTAATGTCCAAAAATGACAGATTTACAAGTGTAAGCTATATGATTTCTTCAAAAAGCAAAAGCAATATACCTAATTCATTTGGATCAAAC
TTACATAGGTCTCAGGTCCTGTAAGAAACTTGCCTGTTCTAACTGTTGCTACCAGATTATATCTGGTGGTAATTGTTAATGTTTCAGCAG
GGCTGGTCTCAGTCCTTTAAAATGGAAAGCTTTATTTGGAGCCCAACCCTATAAGATGAAGAAATCCTATATAGTCTTATTCACCAATAT
ATCCAATACACCCACAGCAATGGTACCTTTTTAAGATCAGGATTTTATTATGAATTCCTGTCACTTTCTGTTTTCCATTTAAATTTCTAT
TTTACAAATTTTTCAGGGAATCATATTCTTAACTTCACTGAGAAAAATGTGTTACTCTTTTGGACAATTTATCTTATTTCTATCATATAA
GATGTATTTTTTTATTGTCCTTAAAAGAAGCTCTAGCATGAAATTAAAGGAAAGGGAAAGAAATAGATCTGGTGCACCCGAACATTAGGA
GAAAATGAAAAATATACAACCAACCGTTCGTGAGTCATCAAAAAGTCAAAGTCAGCCTGGCCAACATGGCAAAACTCCGTCTCTGCAAAA
AATACAAAAATGAGCCCGGTATGTTGGCATATGCCTGTAATCCCAGCTACTCGAGAGGCTGAGACACGAAAATTGCTTGAACCTGGGAGG
CGGAGGTTGCAATGAGCCGAGATCGCGCTACTGCACTCCAGCCTGGGCAACAGAGAGAGACCTTGTCTCAAAAAACAACAACAACAAAAA
GTCAAAGTCATAATAAGCAAATTATTGGCTTCTTTCTTCTAGACTAAAAGAAATTAAAGAGATGAAACAATCAATTGCAAGGGTCAAAAC
TAGATTGGATCTTGGTTTGAATGAAAAAAAGCATAAAATATTCTTGCAATAATTGTAAAAATTTGAATGTGGACTAAGTCCTAGATTATA
TTAAAATATTTTTAATTTTTTAAGCTTGACAAATGCACTGATTGTTATACTTTAAATAACTAAAAATCTGAGAATCCACAGTGCTACAGA
CAATAAGTGATAAAATGGGAAAAAATAGTGAAGATCTTCTTTTAGGAAAACTACCAATAAATGTAGAATGGATGATTCCAAAAAAAAAAA
AAAAAAGAAGAAAGAGAGAAAGAAAGAAACAGAAAAACCTAAAAGAAAGCGAATGAATTTGACACCTGTTGGTTGGATGACAGACCACAC
AGAGGGAGAGTGACCAGGCTTTGCTTGTGGAGCGGGCATCCCTGCCTAGCTATCTCCTTCATGTGCAAGGACAGTATAAGTAGTATTTTG
CATGTGAGTAAACACACCTGCGCAGCCCTGGCTGAGGTCACTAGGCTGGCCAGAGGCAGGACAGGCAGTCTTGAATTTCCTCTAGGGGAG
GCCTGCAGTTTTCCCCACCAACCCCTTTTCACATGCTCCAAAGATGTAGTAGTGTCTGCTGTTTTGGATCGAAAATCACCTTGAGTGGAG
GAAGTGACTTCACTGGGTCTCTGGAGGCTCTCGGAGCTTGAGTGGCTCTGCCCCACCCTGAATCATGCACCCATAAATGCAGTTATGGGT
GGATGTGGGTGTATGAGAGTGGAGATTGTTTTTGTACATTCTCTTTGTTTTCATTTTCCAAATATAATCTTTAATAAACTTGATTTAGTT
TCTTGGGAAATTTATTTTCTACGCTATTCAAAGATATTTTAAATAATATTTTAAAAACATGAAATTTTTTTTTCATTTTTGATTTGATAT
CATTAATTTTATATCAGGATTCATGTAAGAGACTAAAAATGATCCATAGTGGTTAGTACTGTAATTTCTGTTTATTACATGAAATTACAT
TCCATTTATCCAAATATATGTTTATATAATATTTCCACTGTGTGACTCTAGTGATCTTTAACATACACAGAATGATCTACAGTGATCTTT
AACATACTCAGAAATATGAAAAATGTTTGAATATGATCTTTAGGGACTTCTAATGAAAAGGGTATATGAAATGGGAACAATAAATTCTGT
ACATGTATACAGTCCATATACACATTAAGTGTTTGTCATTTGGACAAATTGAAAACTTTTAATAAAGCCATTTTCTTCTTTGTTAAAATG

>51021_51021_4_MAML3-CCDC170_MAML3_chr4_140810511_ENST00000509479_CCDC170_chr6_151869439_ENST00000367290_length(amino acids)=1219AA_BP=692
MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVN
CENRYQQAQVEQLELERRDTVSLYQRTLEQRAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGA
CDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQ
SKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKSD
PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGS
ASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSP
MMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMP
YIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQLRDLRKENEFVKGQIVILEETINVHEM
EAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQ
DAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAENMLET
LQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQ
KERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKASAWLHFIKTLEQ
TKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVT

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Fusion Gene PPI Analysis for MAML3-CCDC170


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MAML3-CCDC170


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MAML3-CCDC170


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource