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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:MAML3-GPATCH8 (FusionGDB2 ID:51026) |
Fusion Gene Summary for MAML3-GPATCH8 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MAML3-GPATCH8 | Fusion gene ID: 51026 | Hgene | Tgene | Gene symbol | MAML3 | GPATCH8 | Gene ID | 55534 | 23131 |
| Gene name | mastermind like transcriptional coactivator 3 | G-patch domain containing 8 | |
| Synonyms | CAGH3|ERDA3|GDN|MAM-2|MAM2|TNRC3|mam-3 | GPATC8|KIAA0553 | |
| Cytomap | 4q31.1 | 17q21.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mastermind-like protein 3CAG repeat containing (glia-derived nexin I alpha)expanded repeat domain, CAG/CTG 3polyglutamine richtrinucleotide repeat containing 3 | G patch domain-containing protein 8 | |
| Modification date | 20200313 | 20200320 | |
| UniProtAcc | Q96JK9 | Q9UKJ3 | |
| Ensembl transtripts involved in fusion gene | ENST00000327122, ENST00000509479, ENST00000398940, | ENST00000586265, ENST00000588554, ENST00000592154, ENST00000434000, ENST00000591680, | |
| Fusion gene scores | * DoF score | 22 X 12 X 8=2112 | 11 X 9 X 7=693 |
| # samples | 23 | 12 | |
| ** MAII score | log2(23/2112*10)=-3.19890406841408 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/693*10)=-2.5298209465287 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MAML3 [Title/Abstract] AND GPATCH8 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | MAML3(140810511)-GPATCH8(42483419), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MAML3 | GO:0007219 | Notch signaling pathway | 12370315 |
| Hgene | MAML3 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 12370315 |
| Fusion gene breakpoints across MAML3 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across GPATCH8 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | PCPG | TCGA-QR-A70H-01A | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
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Fusion Gene ORF analysis for MAML3-GPATCH8 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000327122 | ENST00000586265 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| 5CDS-intron | ENST00000327122 | ENST00000588554 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| 5CDS-intron | ENST00000327122 | ENST00000592154 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| 5CDS-intron | ENST00000509479 | ENST00000586265 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| 5CDS-intron | ENST00000509479 | ENST00000588554 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| 5CDS-intron | ENST00000509479 | ENST00000592154 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| In-frame | ENST00000327122 | ENST00000434000 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| In-frame | ENST00000327122 | ENST00000591680 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| In-frame | ENST00000509479 | ENST00000434000 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| In-frame | ENST00000509479 | ENST00000591680 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| intron-3CDS | ENST00000398940 | ENST00000434000 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| intron-3CDS | ENST00000398940 | ENST00000591680 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| intron-intron | ENST00000398940 | ENST00000586265 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| intron-intron | ENST00000398940 | ENST00000588554 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| intron-intron | ENST00000398940 | ENST00000592154 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000509479 | MAML3 | chr4 | 140810511 | - | ENST00000434000 | GPATCH8 | chr17 | 42483419 | - | 7105 | 2936 | 857 | 6952 | 2031 |
| ENST00000509479 | MAML3 | chr4 | 140810511 | - | ENST00000591680 | GPATCH8 | chr17 | 42483419 | - | 7105 | 2936 | 857 | 6952 | 2031 |
| ENST00000327122 | MAML3 | chr4 | 140810511 | - | ENST00000434000 | GPATCH8 | chr17 | 42483419 | - | 5780 | 1611 | 24 | 5627 | 1867 |
| ENST00000327122 | MAML3 | chr4 | 140810511 | - | ENST00000591680 | GPATCH8 | chr17 | 42483419 | - | 5780 | 1611 | 24 | 5627 | 1867 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000509479 | ENST00000434000 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - | 0.009680337 | 0.9903197 |
| ENST00000509479 | ENST00000591680 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - | 0.009680337 | 0.9903197 |
| ENST00000327122 | ENST00000434000 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - | 0.007346494 | 0.9926535 |
| ENST00000327122 | ENST00000591680 | MAML3 | chr4 | 140810511 | - | GPATCH8 | chr17 | 42483419 | - | 0.007346494 | 0.9926535 |
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Fusion Genomic Features for MAML3-GPATCH8 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for MAML3-GPATCH8 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:140810511/chr17:42483419) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MAML3 | GPATCH8 |
| FUNCTION: Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. {ECO:0000269|PubMed:12370315, ECO:0000269|PubMed:12386158}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MAML3 | chr4:140810511 | chr17:42483419 | ENST00000509479 | - | 2 | 5 | 548_595 | 693 | 1139.0 | Compositional bias | Note=Asn-rich |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000434000 | 6 | 9 | 89_124 | 86 | 1425.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000434000 | 6 | 9 | 1384_1390 | 86 | 1425.0 | Compositional bias | Note=Poly-Ala | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000434000 | 6 | 9 | 1472_1478 | 86 | 1425.0 | Compositional bias | Note=Poly-Ala | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000434000 | 6 | 9 | 665_720 | 86 | 1425.0 | Compositional bias | Note=Lys-rich | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000434000 | 6 | 9 | 745_749 | 86 | 1425.0 | Compositional bias | Note=Poly-Arg | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000434000 | 6 | 9 | 772_775 | 86 | 1425.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000434000 | 6 | 9 | 804_1009 | 86 | 1425.0 | Compositional bias | Note=Ser-rich | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000591680 | 5 | 8 | 1384_1390 | 164 | 1503.0 | Compositional bias | Note=Poly-Ala | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000591680 | 5 | 8 | 1472_1478 | 164 | 1503.0 | Compositional bias | Note=Poly-Ala | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000591680 | 5 | 8 | 665_720 | 164 | 1503.0 | Compositional bias | Note=Lys-rich | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000591680 | 5 | 8 | 745_749 | 164 | 1503.0 | Compositional bias | Note=Poly-Arg | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000591680 | 5 | 8 | 772_775 | 164 | 1503.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000591680 | 5 | 8 | 804_1009 | 164 | 1503.0 | Compositional bias | Note=Ser-rich | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000434000 | 6 | 9 | 136_160 | 86 | 1425.0 | Zinc finger | C2H2-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MAML3 | chr4:140810511 | chr17:42483419 | ENST00000509479 | - | 2 | 5 | 467_968 | 693 | 1139.0 | Compositional bias | Note=Gln-rich |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000591680 | 5 | 8 | 89_124 | 164 | 1503.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000434000 | 6 | 9 | 40_86 | 86 | 1425.0 | Domain | G-patch | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000591680 | 5 | 8 | 40_86 | 164 | 1503.0 | Domain | G-patch | |
| Tgene | GPATCH8 | chr4:140810511 | chr17:42483419 | ENST00000591680 | 5 | 8 | 136_160 | 164 | 1503.0 | Zinc finger | C2H2-type |
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Fusion Gene Sequence for MAML3-GPATCH8 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >51026_51026_1_MAML3-GPATCH8_MAML3_chr4_140810511_ENST00000327122_GPATCH8_chr17_42483419_ENST00000434000_length(transcript)=5780nt_BP=1611nt CTACAAGAGACTGTGAAAAGGAAGTTGGAAGGAGCTCGATCACCACTTAATGGAGACCAGCAGAATGGTGCTTGTGATGGGAATTTTTCT CCGACTAGCAAACGAATTCGAAAGGACATTTCTGCGGGGATGGAAGCCATCAACAATTTGCCCAGTAACATGCCACTGCCTTCAGCTTCT CCTCTTCACCAACTTGACCTGAAACCTTCTTTGCCCTTGCAGAACAGTGGAACTCACACTCCTGGGCTTCTAGAAGATCTAAGTAAGAAT GGTAGGCTCCCTGAGATTAAACTTCCTGTCAACGGTTGCAGTGACCTGGAGGATAGCTTCACCATCTTGCAGAGCAAAGACCTCAAACAA GAACCTCTCGATGACCCTACTTGCATAGACACATCAGAAACATCTCTTTCAAATCAGAACAAGCTGTTCTCAGACATTAATCTGAATGAT CAGGAGTGGCAAGAATTAATAGATGAATTGGCCAACACGGTTCCTGAGGATGACATACAGGACCTGTTCAACGAAGACTTTGAAGAGAAG AAGGAGCCAGAATTCTCGCAGCCAGCAACTGAGACCCCTCTCTCCCAGGAGAGTGCGAGCGTGAAGAGCGACCCCTCTCACTCTCCCTTC GCACATGTCTCCATGGGATCTCCCCAGGCGAGGCCTTCTTCTTCTGGTCCTCCCTTTTCTACTGTCTCCACGGCCACTAGTTTACCTTCT GTTGCCAGCACTCCCGCAGCTCCAAACCCTGCAAGCTCACCAGCAAACTGTGCTGTCCAGTCCCCTCAAACTCCAAACCAAGCCCACACT CCAGGCCAAGCTCCACCTCGGCCTGGAAATGGTTATCTCCTGAATCCGGCAGCAGTGACAGTGGCCGGTTCAGCGTCAGGGCCTGTGGCT GTGCCCAGCTCTGACATGTCTCCAGCAGAACAGCTCAAACAGATGGCTGCACAGCAGCAACAAAGGGCCAAACTCATGCAGCAGAAACAG CAACAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCACTCAAATCAGACTTCA AATTGGTCTCCCTTAGGACCTCCCTCTAGTCCATATGGAGCAGCTTTTACTGCAGAAAAACCAAATAGCCCAATGATGTACCCCCAAGCC TTTAACAACCAAAACCCTATAGTGCCTCCAATGGCAAACAACCTGCAGAAGACAACAATGAATAACTACCTCCCTCAGAATCACATGAAT ATGATCAATCAGCAGCCAAATAACTTGGGTACAAACTCCTTAAACAAACAGCACAATATTCTGACTTATGGCAACACTAAACCCCTGACC CACTTCAATGCAGACCTGAGTCAGAGGATGACACCACCAGTGGCCAACCCCAACAAAAACCCCTTGATGCCGTATATCCAGCAGCAGCAA CAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAGCCGCCACCTCCACAGCTCCAGGCCCCCAGGGCACACCTGAGCGAAGAC CAGAAACGCCTGCTTCTCATGAAGCAGAAAGGAGTGATGAATCAGCCCATGGCTTACGCTGCACTTCCATCCCACGGTCAGAGATTAAAA GATCTGAAGCAGAGAGAGTTTGCTCGAAATGTCTCTTCAAGATCCCGCAAGGATGAGAAAAAACAGGAAAAAGCCCTTCGGCGGCTCCAT GAGTTGGCAGAGCAAAGAAAACAAGCTGAATGTGCACCTGGAAGTGGTCCCATGTTCAAACCAACCACAGTGGCTGTAGATGAAGAAGGT GGAGAAGATGATAAAGATGAATCAGCTACAAATAGTGGCACAGGTGCCACTGCTTCTTGTGGCCTGGGATCTGAATTCTCCACAGATAAA GGAGGCCCTTTCACTGCAGTACAAATCACTAATACCACTGGACTGGCCCAGGCTCCTGGGTTAGCCTCCCAAGGCATCAGCTTTGGCATT AAGAATAATCTGGGGACCCCATTGCAAAAATTGGGAGTGTCATTTTCTTTTGCCAAAAAGGCTCCTGTCAAACTCGAATCAATAGCATCA GTTTTCAAGGACCATGCGGAGGAAGGGACCTCTGAAGATGGAACAAAACCCGATGAGAAGAGTTCTGACCAAGGACTGCAGAAGGTAGGA GACTCTGATGGGAGCAGTAATCTTGATGGTAAAAAAGAGGATGAAGACCCTCAGGATGGAGGGTCCCTTGCCTCAACATTATCCAAATTA AAAAGGATGAAACGAGAAGAAGGAGCTGGGGCTACAGAGCCTGAGTATTACCACTACATCCCCCCAGCACACTGCAAAGTAAAACCTAAT TTTCCCTTTCTACTTTTTATGAGAGCCAGTGAACAAATGGATGGTGATAATACTACACACCCAAAGAATGCCCCAGAGAGTAAAAAAGGC AGTTCTCCCAAGCCTAAAAGCTGCATCAAGGCGGCAGCAAGCCAAGGAGCAGAAAAGACAGTTAGTGAAGTCTCTGAGCAGCCGAAGGAA ACCAGCATGACCGAGCCCTCAGAACCAGGAAGCAAAGCTGAGGCAAAGAAGGCCTTAGGAGGGGATGTAAGTGATCAGAGTTTAGAAAGT CATAGTCAGAAGGTTTCAGAGACCCAAATGTGTGAGTCCAACTCTTCTAAAGAAACCTCTCTGGCCACCCCAGCAGGGAAAGAAAGCCAA GAAGGACCCAAACATCCTACTGGTCCCTTCTTCCCAGTTTTGAGCAAAGATGAAAGCACTGCCCTCCAGTGGCCATCAGAACTATTAATT TTCACCAAGGCAGAACCCTCCATTTCATACAGTTGTAACCCTTTATATTTTGACTTTAAACTTTCAAGGAACAAAGATGCCAGAACTAAA GGAACAGAAAAACCAAAGGATATAGGAAGCTCCTCAAAGGACCATCTCCAAGGCCTAGATCCTGGTGAGCCAAATAAAAGCAAGGAAGTG GGCGGAGAGAAAATAGTACGTTCCTCAGGAGGCAGAATGGACGCACCTGCTTCAGGGTCTGCCTGTAGCGGCCTGAACAAGCAGGAGCCT GGGGGTAGCCATGGGTCTGAGACAGAAGACACAGGGAGAAGCCTTCCCAGCAAGAAAGAACGATCTGGGAAGTCCCACCGGCACAAAAAG AAAAAGAAGCACAAAAAATCCAGCAAACACAAACGTAAACACAAGGCTGACACAGAAGAGAAAAGCTCTAAGGCAGAGTCAGGGGAGAAA TCTAAGAAGCGCAAGAAACGAAAACGAAAGAAGAATAAGTCATCAGCCCCAGCAGATTCTGAACGAGGACCCAAACCAGAACCCCCTGGG AGTGGCAGTCCCGCACCACCAAGAAGAAGGCGGAGAGCTCAAGATGACTCCCAGCGGAGATCCCTCCCAGCTGAAGAGGGGAGCAGTGGC AAAAAGGATGAAGGTGGGGGTGGTAGCAGCTCCCAAGACCATGGTGGGAGGAAACACAAAGGTGAACTTCCACCTTCATCCTGCCAGCGA AGAGCAGGCACCAAACGGAGCAGCCGGTCTAGCCATCGGAGCCAACCCAGTAGTGGAGATGAGGATAGTGATGATGCTTCCTCACACCGG CTGCACCAGAAGTCTCCATCCCAGTACAGTGAGGAAGAAGAAGAGGAAGATTCAGGCAGTGAGCATTCCCGCAGCCGCTCAAGGTCTGGC CGGCGCCATTCCTCGCATCGTTCCTCCCGGCGTTCTTACTCAAGTAGCTCAGATGCCTCTTCAGACCAGAGCTGCTATAGTAGACAGCGC AGTTACTCTGATGACAGCTACAGTGACTACAGTGACAGATCACGAAGGCACTCCAAGCGCTCCCATGACTCAGATGACTCAGACTATGCC AGCTCCAAACACCGATCAAAACGGCACAAATATTCATCTTCTGATGATGACTATAGCCTCAGTTGCAGCCAGTCCCGAAGCCGATCTCGG AGTCATACCAGAGAGCGCTCAAGATCCCGGGGCCGCAGCCGCAGCAGCAGTTGTAGTCGTAGTCGAAGCAAGCGGAGAAGCCGTAGCACC ACAGCCCACAGCTGGCAACGGAGCCGGAGCTATAGCCGGGACCGCAGCCGCAGCACCAGGAGCCCTTCCCAGAGATCAGGCTCCAGGAAG AGATCATGGGGTCACGAGAGCCCTGAGGAGAGGCATTCTGGGCGTCGGGACTTCATTCGTTCTAAGATCTACCGCTCCCAGTCCCCCCAC TATTTCCGATCAGGCCGGGGAGAAGGTCCTGGGAAGAAAGATGATGGCAGAGGAGATGACAGTAAAGCAACAGGTCCACCTTCCCAGAAC AGCAACATTGGCACAGGAAGAGGGTCAGAAGGTGACTGCAGTCCTGAAGACAAGAACTCTGTCACTGCCAAACTGCTACTGGAGAAGATC CAGTCAAGGAAAGTGGAGAGGAAACCTAGTGTGAGTGAGGAGGTGCAGGCCACCCCTAATAAAGCTGGGCCCAAGCTCAAGGACCCCCCA CAAGGTTACTTTGGGCCCAAGCTCCCCCCATCTCTTGGCAATAAGCCTGTCCTTCCACTGATAGGGAAGCTCCCAGCTACCCGAAAGCCC AATAAGAAGTGTGAAGAGTCTGGCTTGGAAAGGGGGGAAGAGCAAGAACAGTCAGAGACAGAAGAGGGGCCCCCAGGGAGTAGTGATGCC CTATTTGGGCATCAGTTCCCTTCAGAGGAAACAACTGGCCCCTTATTAGACCCACCCCCAGAAGAGTCAAAGTCTGGAGAAGCTACTGCT GATCACCCTGTGGCTCCACTAGGCACCCCAGCACATTCTGACTGCTACCCTGGGGACCCAACCATCTCCCATAACTACCTCCCCGACCCC AGTGATGGGGACACCCTGGAGTCCCTGGATAGCAGCAGTCAGCCAGGCCCTGTGGAGTCCAGCTTGCTGCCTATAGCACCAGACCTTGAG CATTTCCCCAGTTATGCACCTCCCAGTGGGGATCCTAGTATTGAGTCAACAGATGGGGCTGAGGATGCTTCACTGGCCCCCCTGGAAAGC CAGCCCATCACCTTCACCCCTGAGGAGATGGAGAAGTACAGCAAGCTCCAGCAGGCTGCTCAGCAACACATCCAGCAGCAGCTTCTGGCC AAGCAAGTAAAGGCCTTTCCAGCCTCAGCTGCCCTGGCCCCAGCCACACCAGCCCTGCAACCCATCCACATTCAGCAGCCAGCTACAGCC TCTGCCACCTCCATCACAACTGTTCAGCATGCCATCCTACAACATCATGCTGCCGCAGCTGCTGCCGCCATCGGCATTCACCCTCACCCC CATCCCCAACCACTTGCCCAGGTGCATCATATTCCCCAGCCCCATCTGACCCCCATTTCTTTGTCCCACCTCACTCACTCAATCATCCCT GGCCACCCTGCCACCTTTCTCGCTAGCCATCCCATCCACATCATTCCCGCCTCAGCCATCCATCCTGGGCCCTTCACCTTTCACCCTGTC CCACATGCTGCCCTCTACCCCACCCTACTTGCTCCACGGCCTGCTGCAGCAGCTGCCACTGCACTTCACCTTCACCCACTACTTCACCCC ATCTTCTCAGGTCAGGACCTGCAACATCCCCCCAGCCATGGCACGTGAGTTGGGGGATGGGATCCTAGGTAGGGCCAGGGGAGGAGACCC ATAAATGTTCCCTTGGGGGTGTTGAGCCATTAATACCAGCAAGTAGAAGCTGGGATGGGCAGTGTCTGACAGCCAAAGAATTGAGTTTTG >51026_51026_1_MAML3-GPATCH8_MAML3_chr4_140810511_ENST00000327122_GPATCH8_chr17_42483419_ENST00000434000_length(amino acids)=1867AA_BP=528 MEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKL PVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQP ATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRP GNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPP SSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQ RMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQRLKDLKQREFA RNVSSRSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESATNSGTGATASCGLGSEFSTDKGGPFTAVQ ITNTTGLAQAPGLASQGISFGIKNNLGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDGSSNL DGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSC IKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTG PFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRS SGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRK RKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSS RSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYS DYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRS RSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRG SEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESG LERGEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLES LDSSSQPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPA SAALAPATPALQPIHIQQPATASATSITTVQHAILQHHAAAAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLA -------------------------------------------------------------- >51026_51026_2_MAML3-GPATCH8_MAML3_chr4_140810511_ENST00000327122_GPATCH8_chr17_42483419_ENST00000591680_length(transcript)=5780nt_BP=1611nt CTACAAGAGACTGTGAAAAGGAAGTTGGAAGGAGCTCGATCACCACTTAATGGAGACCAGCAGAATGGTGCTTGTGATGGGAATTTTTCT CCGACTAGCAAACGAATTCGAAAGGACATTTCTGCGGGGATGGAAGCCATCAACAATTTGCCCAGTAACATGCCACTGCCTTCAGCTTCT CCTCTTCACCAACTTGACCTGAAACCTTCTTTGCCCTTGCAGAACAGTGGAACTCACACTCCTGGGCTTCTAGAAGATCTAAGTAAGAAT GGTAGGCTCCCTGAGATTAAACTTCCTGTCAACGGTTGCAGTGACCTGGAGGATAGCTTCACCATCTTGCAGAGCAAAGACCTCAAACAA GAACCTCTCGATGACCCTACTTGCATAGACACATCAGAAACATCTCTTTCAAATCAGAACAAGCTGTTCTCAGACATTAATCTGAATGAT CAGGAGTGGCAAGAATTAATAGATGAATTGGCCAACACGGTTCCTGAGGATGACATACAGGACCTGTTCAACGAAGACTTTGAAGAGAAG AAGGAGCCAGAATTCTCGCAGCCAGCAACTGAGACCCCTCTCTCCCAGGAGAGTGCGAGCGTGAAGAGCGACCCCTCTCACTCTCCCTTC GCACATGTCTCCATGGGATCTCCCCAGGCGAGGCCTTCTTCTTCTGGTCCTCCCTTTTCTACTGTCTCCACGGCCACTAGTTTACCTTCT GTTGCCAGCACTCCCGCAGCTCCAAACCCTGCAAGCTCACCAGCAAACTGTGCTGTCCAGTCCCCTCAAACTCCAAACCAAGCCCACACT CCAGGCCAAGCTCCACCTCGGCCTGGAAATGGTTATCTCCTGAATCCGGCAGCAGTGACAGTGGCCGGTTCAGCGTCAGGGCCTGTGGCT GTGCCCAGCTCTGACATGTCTCCAGCAGAACAGCTCAAACAGATGGCTGCACAGCAGCAACAAAGGGCCAAACTCATGCAGCAGAAACAG CAACAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCACTCAAATCAGACTTCA AATTGGTCTCCCTTAGGACCTCCCTCTAGTCCATATGGAGCAGCTTTTACTGCAGAAAAACCAAATAGCCCAATGATGTACCCCCAAGCC TTTAACAACCAAAACCCTATAGTGCCTCCAATGGCAAACAACCTGCAGAAGACAACAATGAATAACTACCTCCCTCAGAATCACATGAAT ATGATCAATCAGCAGCCAAATAACTTGGGTACAAACTCCTTAAACAAACAGCACAATATTCTGACTTATGGCAACACTAAACCCCTGACC CACTTCAATGCAGACCTGAGTCAGAGGATGACACCACCAGTGGCCAACCCCAACAAAAACCCCTTGATGCCGTATATCCAGCAGCAGCAA CAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAGCCGCCACCTCCACAGCTCCAGGCCCCCAGGGCACACCTGAGCGAAGAC CAGAAACGCCTGCTTCTCATGAAGCAGAAAGGAGTGATGAATCAGCCCATGGCTTACGCTGCACTTCCATCCCACGGTCAGAGATTAAAA GATCTGAAGCAGAGAGAGTTTGCTCGAAATGTCTCTTCAAGATCCCGCAAGGATGAGAAAAAACAGGAAAAAGCCCTTCGGCGGCTCCAT GAGTTGGCAGAGCAAAGAAAACAAGCTGAATGTGCACCTGGAAGTGGTCCCATGTTCAAACCAACCACAGTGGCTGTAGATGAAGAAGGT GGAGAAGATGATAAAGATGAATCAGCTACAAATAGTGGCACAGGTGCCACTGCTTCTTGTGGCCTGGGATCTGAATTCTCCACAGATAAA GGAGGCCCTTTCACTGCAGTACAAATCACTAATACCACTGGACTGGCCCAGGCTCCTGGGTTAGCCTCCCAAGGCATCAGCTTTGGCATT AAGAATAATCTGGGGACCCCATTGCAAAAATTGGGAGTGTCATTTTCTTTTGCCAAAAAGGCTCCTGTCAAACTCGAATCAATAGCATCA GTTTTCAAGGACCATGCGGAGGAAGGGACCTCTGAAGATGGAACAAAACCCGATGAGAAGAGTTCTGACCAAGGACTGCAGAAGGTAGGA GACTCTGATGGGAGCAGTAATCTTGATGGTAAAAAAGAGGATGAAGACCCTCAGGATGGAGGGTCCCTTGCCTCAACATTATCCAAATTA AAAAGGATGAAACGAGAAGAAGGAGCTGGGGCTACAGAGCCTGAGTATTACCACTACATCCCCCCAGCACACTGCAAAGTAAAACCTAAT TTTCCCTTTCTACTTTTTATGAGAGCCAGTGAACAAATGGATGGTGATAATACTACACACCCAAAGAATGCCCCAGAGAGTAAAAAAGGC AGTTCTCCCAAGCCTAAAAGCTGCATCAAGGCGGCAGCAAGCCAAGGAGCAGAAAAGACAGTTAGTGAAGTCTCTGAGCAGCCGAAGGAA ACCAGCATGACCGAGCCCTCAGAACCAGGAAGCAAAGCTGAGGCAAAGAAGGCCTTAGGAGGGGATGTAAGTGATCAGAGTTTAGAAAGT CATAGTCAGAAGGTTTCAGAGACCCAAATGTGTGAGTCCAACTCTTCTAAAGAAACCTCTCTGGCCACCCCAGCAGGGAAAGAAAGCCAA GAAGGACCCAAACATCCTACTGGTCCCTTCTTCCCAGTTTTGAGCAAAGATGAAAGCACTGCCCTCCAGTGGCCATCAGAACTATTAATT TTCACCAAGGCAGAACCCTCCATTTCATACAGTTGTAACCCTTTATATTTTGACTTTAAACTTTCAAGGAACAAAGATGCCAGAACTAAA GGAACAGAAAAACCAAAGGATATAGGAAGCTCCTCAAAGGACCATCTCCAAGGCCTAGATCCTGGTGAGCCAAATAAAAGCAAGGAAGTG GGCGGAGAGAAAATAGTACGTTCCTCAGGAGGCAGAATGGACGCACCTGCTTCAGGGTCTGCCTGTAGCGGCCTGAACAAGCAGGAGCCT GGGGGTAGCCATGGGTCTGAGACAGAAGACACAGGGAGAAGCCTTCCCAGCAAGAAAGAACGATCTGGGAAGTCCCACCGGCACAAAAAG AAAAAGAAGCACAAAAAATCCAGCAAACACAAACGTAAACACAAGGCTGACACAGAAGAGAAAAGCTCTAAGGCAGAGTCAGGGGAGAAA TCTAAGAAGCGCAAGAAACGAAAACGAAAGAAGAATAAGTCATCAGCCCCAGCAGATTCTGAACGAGGACCCAAACCAGAACCCCCTGGG AGTGGCAGTCCCGCACCACCAAGAAGAAGGCGGAGAGCTCAAGATGACTCCCAGCGGAGATCCCTCCCAGCTGAAGAGGGGAGCAGTGGC AAAAAGGATGAAGGTGGGGGTGGTAGCAGCTCCCAAGACCATGGTGGGAGGAAACACAAAGGTGAACTTCCACCTTCATCCTGCCAGCGA AGAGCAGGCACCAAACGGAGCAGCCGGTCTAGCCATCGGAGCCAACCCAGTAGTGGAGATGAGGATAGTGATGATGCTTCCTCACACCGG CTGCACCAGAAGTCTCCATCCCAGTACAGTGAGGAAGAAGAAGAGGAAGATTCAGGCAGTGAGCATTCCCGCAGCCGCTCAAGGTCTGGC CGGCGCCATTCCTCGCATCGTTCCTCCCGGCGTTCTTACTCAAGTAGCTCAGATGCCTCTTCAGACCAGAGCTGCTATAGTAGACAGCGC AGTTACTCTGATGACAGCTACAGTGACTACAGTGACAGATCACGAAGGCACTCCAAGCGCTCCCATGACTCAGATGACTCAGACTATGCC AGCTCCAAACACCGATCAAAACGGCACAAATATTCATCTTCTGATGATGACTATAGCCTCAGTTGCAGCCAGTCCCGAAGCCGATCTCGG AGTCATACCAGAGAGCGCTCAAGATCCCGGGGCCGCAGCCGCAGCAGCAGTTGTAGTCGTAGTCGAAGCAAGCGGAGAAGCCGTAGCACC ACAGCCCACAGCTGGCAACGGAGCCGGAGCTATAGCCGGGACCGCAGCCGCAGCACCAGGAGCCCTTCCCAGAGATCAGGCTCCAGGAAG AGATCATGGGGTCACGAGAGCCCTGAGGAGAGGCATTCTGGGCGTCGGGACTTCATTCGTTCTAAGATCTACCGCTCCCAGTCCCCCCAC TATTTCCGATCAGGCCGGGGAGAAGGTCCTGGGAAGAAAGATGATGGCAGAGGAGATGACAGTAAAGCAACAGGTCCACCTTCCCAGAAC AGCAACATTGGCACAGGAAGAGGGTCAGAAGGTGACTGCAGTCCTGAAGACAAGAACTCTGTCACTGCCAAACTGCTACTGGAGAAGATC CAGTCAAGGAAAGTGGAGAGGAAACCTAGTGTGAGTGAGGAGGTGCAGGCCACCCCTAATAAAGCTGGGCCCAAGCTCAAGGACCCCCCA CAAGGTTACTTTGGGCCCAAGCTCCCCCCATCTCTTGGCAATAAGCCTGTCCTTCCACTGATAGGGAAGCTCCCAGCTACCCGAAAGCCC AATAAGAAGTGTGAAGAGTCTGGCTTGGAAAGGGGGGAAGAGCAAGAACAGTCAGAGACAGAAGAGGGGCCCCCAGGGAGTAGTGATGCC CTATTTGGGCATCAGTTCCCTTCAGAGGAAACAACTGGCCCCTTATTAGACCCACCCCCAGAAGAGTCAAAGTCTGGAGAAGCTACTGCT GATCACCCTGTGGCTCCACTAGGCACCCCAGCACATTCTGACTGCTACCCTGGGGACCCAACCATCTCCCATAACTACCTCCCCGACCCC AGTGATGGGGACACCCTGGAGTCCCTGGATAGCAGCAGTCAGCCAGGCCCTGTGGAGTCCAGCTTGCTGCCTATAGCACCAGACCTTGAG CATTTCCCCAGTTATGCACCTCCCAGTGGGGATCCTAGTATTGAGTCAACAGATGGGGCTGAGGATGCTTCACTGGCCCCCCTGGAAAGC CAGCCCATCACCTTCACCCCTGAGGAGATGGAGAAGTACAGCAAGCTCCAGCAGGCTGCTCAGCAACACATCCAGCAGCAGCTTCTGGCC AAGCAAGTAAAGGCCTTTCCAGCCTCAGCTGCCCTGGCCCCAGCCACACCAGCCCTGCAACCCATCCACATTCAGCAGCCAGCTACAGCC TCTGCCACCTCCATCACAACTGTTCAGCATGCCATCCTACAACATCATGCTGCCGCAGCTGCTGCCGCCATCGGCATTCACCCTCACCCC CATCCCCAACCACTTGCCCAGGTGCATCATATTCCCCAGCCCCATCTGACCCCCATTTCTTTGTCCCACCTCACTCACTCAATCATCCCT GGCCACCCTGCCACCTTTCTCGCTAGCCATCCCATCCACATCATTCCCGCCTCAGCCATCCATCCTGGGCCCTTCACCTTTCACCCTGTC CCACATGCTGCCCTCTACCCCACCCTACTTGCTCCACGGCCTGCTGCAGCAGCTGCCACTGCACTTCACCTTCACCCACTACTTCACCCC ATCTTCTCAGGTCAGGACCTGCAACATCCCCCCAGCCATGGCACGTGAGTTGGGGGATGGGATCCTAGGTAGGGCCAGGGGAGGAGACCC ATAAATGTTCCCTTGGGGGTGTTGAGCCATTAATACCAGCAAGTAGAAGCTGGGATGGGCAGTGTCTGACAGCCAAAGAATTGAGTTTTG >51026_51026_2_MAML3-GPATCH8_MAML3_chr4_140810511_ENST00000327122_GPATCH8_chr17_42483419_ENST00000591680_length(amino acids)=1867AA_BP=528 MEGARSPLNGDQQNGACDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKL PVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQP ATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRP GNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPP SSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQ RMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQRLKDLKQREFA RNVSSRSRKDEKKQEKALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESATNSGTGATASCGLGSEFSTDKGGPFTAVQ ITNTTGLAQAPGLASQGISFGIKNNLGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDGSSNL DGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSC IKAAASQGAEKTVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTG PFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRS SGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRK RKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSS RSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYS DYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRS RSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRG SEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESG LERGEEQEQSETEEGPPGSSDALFGHQFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLES LDSSSQPGPVESSLLPIAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPA SAALAPATPALQPIHIQQPATASATSITTVQHAILQHHAAAAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLA -------------------------------------------------------------- >51026_51026_3_MAML3-GPATCH8_MAML3_chr4_140810511_ENST00000509479_GPATCH8_chr17_42483419_ENST00000434000_length(transcript)=7105nt_BP=2936nt ACTCCGCTGGCATGGAGGAGGAGGAGGAGGTGGAGGAGCGAGAGGAGGAGGAGGAGGCGGCGGCGGCGGCGGCGGCGAGCAGTTGATCAT TGTGATGGTGGCAGGAGCAGCGGCGGCAGCGGCAGCCCAGCCGAGCGTTAGGTGCTGCTCTCTGCGCGGCGTTTTGCAAAGGACTTCACC GATCTACTTTTGCAGTCGCCTCGGACTGTCCATGTGTTTACTTCCCCCAGCCCGAGGATTCGATATCTAGGTTCCTGTGAAATGCAACTG AGCAGCCAAAGTACTTTGAGAACACGGGGCGGCATAAACACCAAAACTTTTTTGTGGAAGGAAAATGCAATAAGCAAGCTTGCCGTTTTC CGATGCGGTGTGGAGTGAGTGTGTGTCGCGCGTGTCCGCACTGGAGGCATATGCTTGTGTGTGTACATGGGGTGTGTTTTTCGGTATGTA GGGAGAAAATGCTTGCCAACCACCGGAAATCTCCTGGAATTTATTAGAAAATAATGGATTATAAAAAGAAGGCAAGCAAGGAGCGGATCT CCCCTTGAGTTGCAACCCGATTTGCTGCTGGCTCAGTTTGTTGTGATTCTTTTTGTTGATAGGTGTCTGATGGTATTCCGATAACGTTCC CCCCTTTTCTTCCCCTTGAGCTTTTACAGTTTAAAAAAAGGAAACAAAAACCACCCCAAAATCTCCCCCCCCGTTTTTTTCGCCCCGTCG GGATCGCCGTTTCCATCCATGTGCTTGCGTCTCCCCCGCGTTCCACTTAAACTATTTTAATCCTTGGACCCAAGGAGGAGGCTGATAGGG GGGTGGATAAAAAAAGTTCTTCCAAAATAGTGTGCCCGGGGAGCAGGATGGGGGATTTCGCAGCCCCCGCTGCTGCCGCGAATGGCAGTA GTATTTGCATCAACAGTAGCCTGAACAGCAGCCTCGGCGGGGCCGGGATCGGTGTGAATAATACTCCCAATAGTACTCCCGCTGCTCCGA GTAGCAATCACCCGGCAGCCGGTGGATGCGGCGGCTCCGGGGGCCCCGGCGGCGGTTCGGCGGCCGTTCCCAAGCACAGCACCGTGGTGG AGCGGCTCCGCCAGCGCATCGAGGGCTGCCGTCGGCACCACGTCAACTGCGAGAACAGGTACCAGCAGGCTCAGGTGGAGCAGCTGGAGC TGGAGCGCCGGGACACCGTGAGCCTCTACCAGCGGACCCTGGAGCAGAGGGCCAAGAAATCGGGCGCCGGCACCGGCAAACAGCAGCACC CGAGCAAACCCCAGCAAGATGCGGAGGCTGCCTCGGCGGAGCAGAGGAACCACACGCTGATCATGCTACAAGAGACTGTGAAAAGGAAGT TGGAAGGAGCTCGATCACCACTTAATGGAGACCAGCAGAATGGTGCTTGTGATGGGAATTTTTCTCCGACTAGCAAACGAATTCGAAAGG ACATTTCTGCGGGGATGGAAGCCATCAACAATTTGCCCAGTAACATGCCACTGCCTTCAGCTTCTCCTCTTCACCAACTTGACCTGAAAC CTTCTTTGCCCTTGCAGAACAGTGGAACTCACACTCCTGGGCTTCTAGAAGATCTAAGTAAGAATGGTAGGCTCCCTGAGATTAAACTTC CTGTCAACGGTTGCAGTGACCTGGAGGATAGCTTCACCATCTTGCAGAGCAAAGACCTCAAACAAGAACCTCTCGATGACCCTACTTGCA TAGACACATCAGAAACATCTCTTTCAAATCAGAACAAGCTGTTCTCAGACATTAATCTGAATGATCAGGAGTGGCAAGAATTAATAGATG AATTGGCCAACACGGTTCCTGAGGATGACATACAGGACCTGTTCAACGAAGACTTTGAAGAGAAGAAGGAGCCAGAATTCTCGCAGCCAG CAACTGAGACCCCTCTCTCCCAGGAGAGTGCGAGCGTGAAGAGCGACCCCTCTCACTCTCCCTTCGCACATGTCTCCATGGGATCTCCCC AGGCGAGGCCTTCTTCTTCTGGTCCTCCCTTTTCTACTGTCTCCACGGCCACTAGTTTACCTTCTGTTGCCAGCACTCCCGCAGCTCCAA ACCCTGCAAGCTCACCAGCAAACTGTGCTGTCCAGTCCCCTCAAACTCCAAACCAAGCCCACACTCCAGGCCAAGCTCCACCTCGGCCTG GAAATGGTTATCTCCTGAATCCGGCAGCAGTGACAGTGGCCGGTTCAGCGTCAGGGCCTGTGGCTGTGCCCAGCTCTGACATGTCTCCAG CAGAACAGCTCAAACAGATGGCTGCACAGCAGCAACAAAGGGCCAAACTCATGCAGCAGAAACAGCAACAGCAACAGCAGCAGCAGCAGC AGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCACTCAAATCAGACTTCAAATTGGTCTCCCTTAGGACCTCCCT CTAGTCCATATGGAGCAGCTTTTACTGCAGAAAAACCAAATAGCCCAATGATGTACCCCCAAGCCTTTAACAACCAAAACCCTATAGTGC CTCCAATGGCAAACAACCTGCAGAAGACAACAATGAATAACTACCTCCCTCAGAATCACATGAATATGATCAATCAGCAGCCAAATAACT TGGGTACAAACTCCTTAAACAAACAGCACAATATTCTGACTTATGGCAACACTAAACCCCTGACCCACTTCAATGCAGACCTGAGTCAGA GGATGACACCACCAGTGGCCAACCCCAACAAAAACCCCTTGATGCCGTATATCCAGCAGCAGCAACAGCAGCAGCAACAGCAACAGCAGC AGCAGCAGCAGCAGCAGCCGCCACCTCCACAGCTCCAGGCCCCCAGGGCACACCTGAGCGAAGACCAGAAACGCCTGCTTCTCATGAAGC AGAAAGGAGTGATGAATCAGCCCATGGCTTACGCTGCACTTCCATCCCACGGTCAGAGATTAAAAGATCTGAAGCAGAGAGAGTTTGCTC GAAATGTCTCTTCAAGATCCCGCAAGGATGAGAAAAAACAGGAAAAAGCCCTTCGGCGGCTCCATGAGTTGGCAGAGCAAAGAAAACAAG CTGAATGTGCACCTGGAAGTGGTCCCATGTTCAAACCAACCACAGTGGCTGTAGATGAAGAAGGTGGAGAAGATGATAAAGATGAATCAG CTACAAATAGTGGCACAGGTGCCACTGCTTCTTGTGGCCTGGGATCTGAATTCTCCACAGATAAAGGAGGCCCTTTCACTGCAGTACAAA TCACTAATACCACTGGACTGGCCCAGGCTCCTGGGTTAGCCTCCCAAGGCATCAGCTTTGGCATTAAGAATAATCTGGGGACCCCATTGC AAAAATTGGGAGTGTCATTTTCTTTTGCCAAAAAGGCTCCTGTCAAACTCGAATCAATAGCATCAGTTTTCAAGGACCATGCGGAGGAAG GGACCTCTGAAGATGGAACAAAACCCGATGAGAAGAGTTCTGACCAAGGACTGCAGAAGGTAGGAGACTCTGATGGGAGCAGTAATCTTG ATGGTAAAAAAGAGGATGAAGACCCTCAGGATGGAGGGTCCCTTGCCTCAACATTATCCAAATTAAAAAGGATGAAACGAGAAGAAGGAG CTGGGGCTACAGAGCCTGAGTATTACCACTACATCCCCCCAGCACACTGCAAAGTAAAACCTAATTTTCCCTTTCTACTTTTTATGAGAG CCAGTGAACAAATGGATGGTGATAATACTACACACCCAAAGAATGCCCCAGAGAGTAAAAAAGGCAGTTCTCCCAAGCCTAAAAGCTGCA TCAAGGCGGCAGCAAGCCAAGGAGCAGAAAAGACAGTTAGTGAAGTCTCTGAGCAGCCGAAGGAAACCAGCATGACCGAGCCCTCAGAAC CAGGAAGCAAAGCTGAGGCAAAGAAGGCCTTAGGAGGGGATGTAAGTGATCAGAGTTTAGAAAGTCATAGTCAGAAGGTTTCAGAGACCC AAATGTGTGAGTCCAACTCTTCTAAAGAAACCTCTCTGGCCACCCCAGCAGGGAAAGAAAGCCAAGAAGGACCCAAACATCCTACTGGTC CCTTCTTCCCAGTTTTGAGCAAAGATGAAAGCACTGCCCTCCAGTGGCCATCAGAACTATTAATTTTCACCAAGGCAGAACCCTCCATTT CATACAGTTGTAACCCTTTATATTTTGACTTTAAACTTTCAAGGAACAAAGATGCCAGAACTAAAGGAACAGAAAAACCAAAGGATATAG GAAGCTCCTCAAAGGACCATCTCCAAGGCCTAGATCCTGGTGAGCCAAATAAAAGCAAGGAAGTGGGCGGAGAGAAAATAGTACGTTCCT CAGGAGGCAGAATGGACGCACCTGCTTCAGGGTCTGCCTGTAGCGGCCTGAACAAGCAGGAGCCTGGGGGTAGCCATGGGTCTGAGACAG AAGACACAGGGAGAAGCCTTCCCAGCAAGAAAGAACGATCTGGGAAGTCCCACCGGCACAAAAAGAAAAAGAAGCACAAAAAATCCAGCA AACACAAACGTAAACACAAGGCTGACACAGAAGAGAAAAGCTCTAAGGCAGAGTCAGGGGAGAAATCTAAGAAGCGCAAGAAACGAAAAC GAAAGAAGAATAAGTCATCAGCCCCAGCAGATTCTGAACGAGGACCCAAACCAGAACCCCCTGGGAGTGGCAGTCCCGCACCACCAAGAA GAAGGCGGAGAGCTCAAGATGACTCCCAGCGGAGATCCCTCCCAGCTGAAGAGGGGAGCAGTGGCAAAAAGGATGAAGGTGGGGGTGGTA GCAGCTCCCAAGACCATGGTGGGAGGAAACACAAAGGTGAACTTCCACCTTCATCCTGCCAGCGAAGAGCAGGCACCAAACGGAGCAGCC GGTCTAGCCATCGGAGCCAACCCAGTAGTGGAGATGAGGATAGTGATGATGCTTCCTCACACCGGCTGCACCAGAAGTCTCCATCCCAGT ACAGTGAGGAAGAAGAAGAGGAAGATTCAGGCAGTGAGCATTCCCGCAGCCGCTCAAGGTCTGGCCGGCGCCATTCCTCGCATCGTTCCT CCCGGCGTTCTTACTCAAGTAGCTCAGATGCCTCTTCAGACCAGAGCTGCTATAGTAGACAGCGCAGTTACTCTGATGACAGCTACAGTG ACTACAGTGACAGATCACGAAGGCACTCCAAGCGCTCCCATGACTCAGATGACTCAGACTATGCCAGCTCCAAACACCGATCAAAACGGC ACAAATATTCATCTTCTGATGATGACTATAGCCTCAGTTGCAGCCAGTCCCGAAGCCGATCTCGGAGTCATACCAGAGAGCGCTCAAGAT CCCGGGGCCGCAGCCGCAGCAGCAGTTGTAGTCGTAGTCGAAGCAAGCGGAGAAGCCGTAGCACCACAGCCCACAGCTGGCAACGGAGCC GGAGCTATAGCCGGGACCGCAGCCGCAGCACCAGGAGCCCTTCCCAGAGATCAGGCTCCAGGAAGAGATCATGGGGTCACGAGAGCCCTG AGGAGAGGCATTCTGGGCGTCGGGACTTCATTCGTTCTAAGATCTACCGCTCCCAGTCCCCCCACTATTTCCGATCAGGCCGGGGAGAAG GTCCTGGGAAGAAAGATGATGGCAGAGGAGATGACAGTAAAGCAACAGGTCCACCTTCCCAGAACAGCAACATTGGCACAGGAAGAGGGT CAGAAGGTGACTGCAGTCCTGAAGACAAGAACTCTGTCACTGCCAAACTGCTACTGGAGAAGATCCAGTCAAGGAAAGTGGAGAGGAAAC CTAGTGTGAGTGAGGAGGTGCAGGCCACCCCTAATAAAGCTGGGCCCAAGCTCAAGGACCCCCCACAAGGTTACTTTGGGCCCAAGCTCC CCCCATCTCTTGGCAATAAGCCTGTCCTTCCACTGATAGGGAAGCTCCCAGCTACCCGAAAGCCCAATAAGAAGTGTGAAGAGTCTGGCT TGGAAAGGGGGGAAGAGCAAGAACAGTCAGAGACAGAAGAGGGGCCCCCAGGGAGTAGTGATGCCCTATTTGGGCATCAGTTCCCTTCAG AGGAAACAACTGGCCCCTTATTAGACCCACCCCCAGAAGAGTCAAAGTCTGGAGAAGCTACTGCTGATCACCCTGTGGCTCCACTAGGCA CCCCAGCACATTCTGACTGCTACCCTGGGGACCCAACCATCTCCCATAACTACCTCCCCGACCCCAGTGATGGGGACACCCTGGAGTCCC TGGATAGCAGCAGTCAGCCAGGCCCTGTGGAGTCCAGCTTGCTGCCTATAGCACCAGACCTTGAGCATTTCCCCAGTTATGCACCTCCCA GTGGGGATCCTAGTATTGAGTCAACAGATGGGGCTGAGGATGCTTCACTGGCCCCCCTGGAAAGCCAGCCCATCACCTTCACCCCTGAGG AGATGGAGAAGTACAGCAAGCTCCAGCAGGCTGCTCAGCAACACATCCAGCAGCAGCTTCTGGCCAAGCAAGTAAAGGCCTTTCCAGCCT CAGCTGCCCTGGCCCCAGCCACACCAGCCCTGCAACCCATCCACATTCAGCAGCCAGCTACAGCCTCTGCCACCTCCATCACAACTGTTC AGCATGCCATCCTACAACATCATGCTGCCGCAGCTGCTGCCGCCATCGGCATTCACCCTCACCCCCATCCCCAACCACTTGCCCAGGTGC ATCATATTCCCCAGCCCCATCTGACCCCCATTTCTTTGTCCCACCTCACTCACTCAATCATCCCTGGCCACCCTGCCACCTTTCTCGCTA GCCATCCCATCCACATCATTCCCGCCTCAGCCATCCATCCTGGGCCCTTCACCTTTCACCCTGTCCCACATGCTGCCCTCTACCCCACCC TACTTGCTCCACGGCCTGCTGCAGCAGCTGCCACTGCACTTCACCTTCACCCACTACTTCACCCCATCTTCTCAGGTCAGGACCTGCAAC ATCCCCCCAGCCATGGCACGTGAGTTGGGGGATGGGATCCTAGGTAGGGCCAGGGGAGGAGACCCATAAATGTTCCCTTGGGGGTGTTGA >51026_51026_3_MAML3-GPATCH8_MAML3_chr4_140810511_ENST00000509479_GPATCH8_chr17_42483419_ENST00000434000_length(amino acids)=2031AA_BP=692 MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVN CENRYQQAQVEQLELERRDTVSLYQRTLEQRAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGA CDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQ SKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKSD PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGS ASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSP MMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMP YIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQRLKDLKQREFARNVSSRSRKDEKKQEK ALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESATNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQ GISFGIKNNLGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLA STLSKLKRMKREEGAGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEV SEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQW PSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSG LNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGP KPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSD DASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDS DDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQ RSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAK LLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGP PGSSDALFGHQFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDSSSQPGPVESSLLP IAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPASAALAPATPALQPIHI QQPATASATSITTVQHAILQHHAAAAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLASHPIHIIPASAIHPGP -------------------------------------------------------------- >51026_51026_4_MAML3-GPATCH8_MAML3_chr4_140810511_ENST00000509479_GPATCH8_chr17_42483419_ENST00000591680_length(transcript)=7105nt_BP=2936nt ACTCCGCTGGCATGGAGGAGGAGGAGGAGGTGGAGGAGCGAGAGGAGGAGGAGGAGGCGGCGGCGGCGGCGGCGGCGAGCAGTTGATCAT TGTGATGGTGGCAGGAGCAGCGGCGGCAGCGGCAGCCCAGCCGAGCGTTAGGTGCTGCTCTCTGCGCGGCGTTTTGCAAAGGACTTCACC GATCTACTTTTGCAGTCGCCTCGGACTGTCCATGTGTTTACTTCCCCCAGCCCGAGGATTCGATATCTAGGTTCCTGTGAAATGCAACTG AGCAGCCAAAGTACTTTGAGAACACGGGGCGGCATAAACACCAAAACTTTTTTGTGGAAGGAAAATGCAATAAGCAAGCTTGCCGTTTTC CGATGCGGTGTGGAGTGAGTGTGTGTCGCGCGTGTCCGCACTGGAGGCATATGCTTGTGTGTGTACATGGGGTGTGTTTTTCGGTATGTA GGGAGAAAATGCTTGCCAACCACCGGAAATCTCCTGGAATTTATTAGAAAATAATGGATTATAAAAAGAAGGCAAGCAAGGAGCGGATCT CCCCTTGAGTTGCAACCCGATTTGCTGCTGGCTCAGTTTGTTGTGATTCTTTTTGTTGATAGGTGTCTGATGGTATTCCGATAACGTTCC CCCCTTTTCTTCCCCTTGAGCTTTTACAGTTTAAAAAAAGGAAACAAAAACCACCCCAAAATCTCCCCCCCCGTTTTTTTCGCCCCGTCG GGATCGCCGTTTCCATCCATGTGCTTGCGTCTCCCCCGCGTTCCACTTAAACTATTTTAATCCTTGGACCCAAGGAGGAGGCTGATAGGG GGGTGGATAAAAAAAGTTCTTCCAAAATAGTGTGCCCGGGGAGCAGGATGGGGGATTTCGCAGCCCCCGCTGCTGCCGCGAATGGCAGTA GTATTTGCATCAACAGTAGCCTGAACAGCAGCCTCGGCGGGGCCGGGATCGGTGTGAATAATACTCCCAATAGTACTCCCGCTGCTCCGA GTAGCAATCACCCGGCAGCCGGTGGATGCGGCGGCTCCGGGGGCCCCGGCGGCGGTTCGGCGGCCGTTCCCAAGCACAGCACCGTGGTGG AGCGGCTCCGCCAGCGCATCGAGGGCTGCCGTCGGCACCACGTCAACTGCGAGAACAGGTACCAGCAGGCTCAGGTGGAGCAGCTGGAGC TGGAGCGCCGGGACACCGTGAGCCTCTACCAGCGGACCCTGGAGCAGAGGGCCAAGAAATCGGGCGCCGGCACCGGCAAACAGCAGCACC CGAGCAAACCCCAGCAAGATGCGGAGGCTGCCTCGGCGGAGCAGAGGAACCACACGCTGATCATGCTACAAGAGACTGTGAAAAGGAAGT TGGAAGGAGCTCGATCACCACTTAATGGAGACCAGCAGAATGGTGCTTGTGATGGGAATTTTTCTCCGACTAGCAAACGAATTCGAAAGG ACATTTCTGCGGGGATGGAAGCCATCAACAATTTGCCCAGTAACATGCCACTGCCTTCAGCTTCTCCTCTTCACCAACTTGACCTGAAAC CTTCTTTGCCCTTGCAGAACAGTGGAACTCACACTCCTGGGCTTCTAGAAGATCTAAGTAAGAATGGTAGGCTCCCTGAGATTAAACTTC CTGTCAACGGTTGCAGTGACCTGGAGGATAGCTTCACCATCTTGCAGAGCAAAGACCTCAAACAAGAACCTCTCGATGACCCTACTTGCA TAGACACATCAGAAACATCTCTTTCAAATCAGAACAAGCTGTTCTCAGACATTAATCTGAATGATCAGGAGTGGCAAGAATTAATAGATG AATTGGCCAACACGGTTCCTGAGGATGACATACAGGACCTGTTCAACGAAGACTTTGAAGAGAAGAAGGAGCCAGAATTCTCGCAGCCAG CAACTGAGACCCCTCTCTCCCAGGAGAGTGCGAGCGTGAAGAGCGACCCCTCTCACTCTCCCTTCGCACATGTCTCCATGGGATCTCCCC AGGCGAGGCCTTCTTCTTCTGGTCCTCCCTTTTCTACTGTCTCCACGGCCACTAGTTTACCTTCTGTTGCCAGCACTCCCGCAGCTCCAA ACCCTGCAAGCTCACCAGCAAACTGTGCTGTCCAGTCCCCTCAAACTCCAAACCAAGCCCACACTCCAGGCCAAGCTCCACCTCGGCCTG GAAATGGTTATCTCCTGAATCCGGCAGCAGTGACAGTGGCCGGTTCAGCGTCAGGGCCTGTGGCTGTGCCCAGCTCTGACATGTCTCCAG CAGAACAGCTCAAACAGATGGCTGCACAGCAGCAACAAAGGGCCAAACTCATGCAGCAGAAACAGCAACAGCAACAGCAGCAGCAGCAGC AGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAACAGCACTCAAATCAGACTTCAAATTGGTCTCCCTTAGGACCTCCCT CTAGTCCATATGGAGCAGCTTTTACTGCAGAAAAACCAAATAGCCCAATGATGTACCCCCAAGCCTTTAACAACCAAAACCCTATAGTGC CTCCAATGGCAAACAACCTGCAGAAGACAACAATGAATAACTACCTCCCTCAGAATCACATGAATATGATCAATCAGCAGCCAAATAACT TGGGTACAAACTCCTTAAACAAACAGCACAATATTCTGACTTATGGCAACACTAAACCCCTGACCCACTTCAATGCAGACCTGAGTCAGA GGATGACACCACCAGTGGCCAACCCCAACAAAAACCCCTTGATGCCGTATATCCAGCAGCAGCAACAGCAGCAGCAACAGCAACAGCAGC AGCAGCAGCAGCAGCAGCCGCCACCTCCACAGCTCCAGGCCCCCAGGGCACACCTGAGCGAAGACCAGAAACGCCTGCTTCTCATGAAGC AGAAAGGAGTGATGAATCAGCCCATGGCTTACGCTGCACTTCCATCCCACGGTCAGAGATTAAAAGATCTGAAGCAGAGAGAGTTTGCTC GAAATGTCTCTTCAAGATCCCGCAAGGATGAGAAAAAACAGGAAAAAGCCCTTCGGCGGCTCCATGAGTTGGCAGAGCAAAGAAAACAAG CTGAATGTGCACCTGGAAGTGGTCCCATGTTCAAACCAACCACAGTGGCTGTAGATGAAGAAGGTGGAGAAGATGATAAAGATGAATCAG CTACAAATAGTGGCACAGGTGCCACTGCTTCTTGTGGCCTGGGATCTGAATTCTCCACAGATAAAGGAGGCCCTTTCACTGCAGTACAAA TCACTAATACCACTGGACTGGCCCAGGCTCCTGGGTTAGCCTCCCAAGGCATCAGCTTTGGCATTAAGAATAATCTGGGGACCCCATTGC AAAAATTGGGAGTGTCATTTTCTTTTGCCAAAAAGGCTCCTGTCAAACTCGAATCAATAGCATCAGTTTTCAAGGACCATGCGGAGGAAG GGACCTCTGAAGATGGAACAAAACCCGATGAGAAGAGTTCTGACCAAGGACTGCAGAAGGTAGGAGACTCTGATGGGAGCAGTAATCTTG ATGGTAAAAAAGAGGATGAAGACCCTCAGGATGGAGGGTCCCTTGCCTCAACATTATCCAAATTAAAAAGGATGAAACGAGAAGAAGGAG CTGGGGCTACAGAGCCTGAGTATTACCACTACATCCCCCCAGCACACTGCAAAGTAAAACCTAATTTTCCCTTTCTACTTTTTATGAGAG CCAGTGAACAAATGGATGGTGATAATACTACACACCCAAAGAATGCCCCAGAGAGTAAAAAAGGCAGTTCTCCCAAGCCTAAAAGCTGCA TCAAGGCGGCAGCAAGCCAAGGAGCAGAAAAGACAGTTAGTGAAGTCTCTGAGCAGCCGAAGGAAACCAGCATGACCGAGCCCTCAGAAC CAGGAAGCAAAGCTGAGGCAAAGAAGGCCTTAGGAGGGGATGTAAGTGATCAGAGTTTAGAAAGTCATAGTCAGAAGGTTTCAGAGACCC AAATGTGTGAGTCCAACTCTTCTAAAGAAACCTCTCTGGCCACCCCAGCAGGGAAAGAAAGCCAAGAAGGACCCAAACATCCTACTGGTC CCTTCTTCCCAGTTTTGAGCAAAGATGAAAGCACTGCCCTCCAGTGGCCATCAGAACTATTAATTTTCACCAAGGCAGAACCCTCCATTT CATACAGTTGTAACCCTTTATATTTTGACTTTAAACTTTCAAGGAACAAAGATGCCAGAACTAAAGGAACAGAAAAACCAAAGGATATAG GAAGCTCCTCAAAGGACCATCTCCAAGGCCTAGATCCTGGTGAGCCAAATAAAAGCAAGGAAGTGGGCGGAGAGAAAATAGTACGTTCCT CAGGAGGCAGAATGGACGCACCTGCTTCAGGGTCTGCCTGTAGCGGCCTGAACAAGCAGGAGCCTGGGGGTAGCCATGGGTCTGAGACAG AAGACACAGGGAGAAGCCTTCCCAGCAAGAAAGAACGATCTGGGAAGTCCCACCGGCACAAAAAGAAAAAGAAGCACAAAAAATCCAGCA AACACAAACGTAAACACAAGGCTGACACAGAAGAGAAAAGCTCTAAGGCAGAGTCAGGGGAGAAATCTAAGAAGCGCAAGAAACGAAAAC GAAAGAAGAATAAGTCATCAGCCCCAGCAGATTCTGAACGAGGACCCAAACCAGAACCCCCTGGGAGTGGCAGTCCCGCACCACCAAGAA GAAGGCGGAGAGCTCAAGATGACTCCCAGCGGAGATCCCTCCCAGCTGAAGAGGGGAGCAGTGGCAAAAAGGATGAAGGTGGGGGTGGTA GCAGCTCCCAAGACCATGGTGGGAGGAAACACAAAGGTGAACTTCCACCTTCATCCTGCCAGCGAAGAGCAGGCACCAAACGGAGCAGCC GGTCTAGCCATCGGAGCCAACCCAGTAGTGGAGATGAGGATAGTGATGATGCTTCCTCACACCGGCTGCACCAGAAGTCTCCATCCCAGT ACAGTGAGGAAGAAGAAGAGGAAGATTCAGGCAGTGAGCATTCCCGCAGCCGCTCAAGGTCTGGCCGGCGCCATTCCTCGCATCGTTCCT CCCGGCGTTCTTACTCAAGTAGCTCAGATGCCTCTTCAGACCAGAGCTGCTATAGTAGACAGCGCAGTTACTCTGATGACAGCTACAGTG ACTACAGTGACAGATCACGAAGGCACTCCAAGCGCTCCCATGACTCAGATGACTCAGACTATGCCAGCTCCAAACACCGATCAAAACGGC ACAAATATTCATCTTCTGATGATGACTATAGCCTCAGTTGCAGCCAGTCCCGAAGCCGATCTCGGAGTCATACCAGAGAGCGCTCAAGAT CCCGGGGCCGCAGCCGCAGCAGCAGTTGTAGTCGTAGTCGAAGCAAGCGGAGAAGCCGTAGCACCACAGCCCACAGCTGGCAACGGAGCC GGAGCTATAGCCGGGACCGCAGCCGCAGCACCAGGAGCCCTTCCCAGAGATCAGGCTCCAGGAAGAGATCATGGGGTCACGAGAGCCCTG AGGAGAGGCATTCTGGGCGTCGGGACTTCATTCGTTCTAAGATCTACCGCTCCCAGTCCCCCCACTATTTCCGATCAGGCCGGGGAGAAG GTCCTGGGAAGAAAGATGATGGCAGAGGAGATGACAGTAAAGCAACAGGTCCACCTTCCCAGAACAGCAACATTGGCACAGGAAGAGGGT CAGAAGGTGACTGCAGTCCTGAAGACAAGAACTCTGTCACTGCCAAACTGCTACTGGAGAAGATCCAGTCAAGGAAAGTGGAGAGGAAAC CTAGTGTGAGTGAGGAGGTGCAGGCCACCCCTAATAAAGCTGGGCCCAAGCTCAAGGACCCCCCACAAGGTTACTTTGGGCCCAAGCTCC CCCCATCTCTTGGCAATAAGCCTGTCCTTCCACTGATAGGGAAGCTCCCAGCTACCCGAAAGCCCAATAAGAAGTGTGAAGAGTCTGGCT TGGAAAGGGGGGAAGAGCAAGAACAGTCAGAGACAGAAGAGGGGCCCCCAGGGAGTAGTGATGCCCTATTTGGGCATCAGTTCCCTTCAG AGGAAACAACTGGCCCCTTATTAGACCCACCCCCAGAAGAGTCAAAGTCTGGAGAAGCTACTGCTGATCACCCTGTGGCTCCACTAGGCA CCCCAGCACATTCTGACTGCTACCCTGGGGACCCAACCATCTCCCATAACTACCTCCCCGACCCCAGTGATGGGGACACCCTGGAGTCCC TGGATAGCAGCAGTCAGCCAGGCCCTGTGGAGTCCAGCTTGCTGCCTATAGCACCAGACCTTGAGCATTTCCCCAGTTATGCACCTCCCA GTGGGGATCCTAGTATTGAGTCAACAGATGGGGCTGAGGATGCTTCACTGGCCCCCCTGGAAAGCCAGCCCATCACCTTCACCCCTGAGG AGATGGAGAAGTACAGCAAGCTCCAGCAGGCTGCTCAGCAACACATCCAGCAGCAGCTTCTGGCCAAGCAAGTAAAGGCCTTTCCAGCCT CAGCTGCCCTGGCCCCAGCCACACCAGCCCTGCAACCCATCCACATTCAGCAGCCAGCTACAGCCTCTGCCACCTCCATCACAACTGTTC AGCATGCCATCCTACAACATCATGCTGCCGCAGCTGCTGCCGCCATCGGCATTCACCCTCACCCCCATCCCCAACCACTTGCCCAGGTGC ATCATATTCCCCAGCCCCATCTGACCCCCATTTCTTTGTCCCACCTCACTCACTCAATCATCCCTGGCCACCCTGCCACCTTTCTCGCTA GCCATCCCATCCACATCATTCCCGCCTCAGCCATCCATCCTGGGCCCTTCACCTTTCACCCTGTCCCACATGCTGCCCTCTACCCCACCC TACTTGCTCCACGGCCTGCTGCAGCAGCTGCCACTGCACTTCACCTTCACCCACTACTTCACCCCATCTTCTCAGGTCAGGACCTGCAAC ATCCCCCCAGCCATGGCACGTGAGTTGGGGGATGGGATCCTAGGTAGGGCCAGGGGAGGAGACCCATAAATGTTCCCTTGGGGGTGTTGA >51026_51026_4_MAML3-GPATCH8_MAML3_chr4_140810511_ENST00000509479_GPATCH8_chr17_42483419_ENST00000591680_length(amino acids)=2031AA_BP=692 MGDFAAPAAAANGSSICINSSLNSSLGGAGIGVNNTPNSTPAAPSSNHPAAGGCGGSGGPGGGSAAVPKHSTVVERLRQRIEGCRRHHVN CENRYQQAQVEQLELERRDTVSLYQRTLEQRAKKSGAGTGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGA CDGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLPLQNSGTHTPGLLEDLSKNGRLPEIKLPVNGCSDLEDSFTILQ SKDLKQEPLDDPTCIDTSETSLSNQNKLFSDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKSD PSHSPFAHVSMGSPQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGS ASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSP MMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMP YIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQRLKDLKQREFARNVSSRSRKDEKKQEK ALRRLHELAEQRKQAECAPGSGPMFKPTTVAVDEEGGEDDKDESATNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQ GISFGIKNNLGTPLQKLGVSFSFAKKAPVKLESIASVFKDHAEEGTSEDGTKPDEKSSDQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLA STLSKLKRMKREEGAGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSEV SEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSKDESTALQW PSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGSACSG LNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGP KPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSD DASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDS DDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQ RSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAK LLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPKLPPSLGNKPVLPLIGKLPATRKPNKKCEESGLERGEEQEQSETEEGP PGSSDALFGHQFPSEETTGPLLDPPPEESKSGEATADHPVAPLGTPAHSDCYPGDPTISHNYLPDPSDGDTLESLDSSSQPGPVESSLLP IAPDLEHFPSYAPPSGDPSIESTDGAEDASLAPLESQPITFTPEEMEKYSKLQQAAQQHIQQQLLAKQVKAFPASAALAPATPALQPIHI QQPATASATSITTVQHAILQHHAAAAAAAIGIHPHPHPQPLAQVHHIPQPHLTPISLSHLTHSIIPGHPATFLASHPIHIIPASAIHPGP -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for MAML3-GPATCH8 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for MAML3-GPATCH8 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for MAML3-GPATCH8 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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