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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MAP3K7-KIAA1009 (FusionGDB2 ID:51349)

Fusion Gene Summary for MAP3K7-KIAA1009

check button Fusion gene summary
Fusion gene informationFusion gene name: MAP3K7-KIAA1009
Fusion gene ID: 51349
HgeneTgene
Gene symbol

MAP3K7

KIAA1009

Gene ID

6885

22832

Gene namemitogen-activated protein kinase kinase kinase 7centrosomal protein 162
SynonymsCSCF|FMD2|MEKK7|TAK1|TGF1aC6orf84|KIAA1009|QN1
Cytomap

6q15

6q14.2-q14.3

Type of geneprotein-codingprotein-coding
Descriptionmitogen-activated protein kinase kinase kinase 7TGF-beta activated kinase 1transforming growth factor-beta-activated kinase 1centrosomal protein of 162 kDacentrosomal protein 162kDaprotein QN1 homolog
Modification date2020031320200320
UniProtAcc

O43318

.
Ensembl transtripts involved in fusion geneENST00000369325, ENST00000369327, 
ENST00000369329, ENST00000369332, 
ENST00000369320, ENST00000479630, 
ENST00000461137, ENST00000257766, 
ENST00000403245, 
Fusion gene scores* DoF score9 X 8 X 6=4323 X 3 X 2=18
# samples 103
** MAII scorelog2(10/432*10)=-2.11103131238874
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: MAP3K7 [Title/Abstract] AND KIAA1009 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMAP3K7(91296482)-KIAA1009(84872989), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMAP3K7

GO:0000186

activation of MAPKK activity

8663074|9079627

HgeneMAP3K7

GO:0000187

activation of MAPK activity

9079627

HgeneMAP3K7

GO:0007252

I-kappaB phosphorylation

11460167

HgeneMAP3K7

GO:0007254

JNK cascade

9079627

HgeneMAP3K7

GO:0043507

positive regulation of JUN kinase activity

11460167

HgeneMAP3K7

GO:0043966

histone H3 acetylation

18838386

HgeneMAP3K7

GO:0051403

stress-activated MAPK cascade

9079627


check buttonFusion gene breakpoints across MAP3K7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KIAA1009 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-VR-A8EXMAP3K7chr6

91296482

-KIAA1009chr6

84872989

-


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Fusion Gene ORF analysis for MAP3K7-KIAA1009

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000369325ENST00000461137MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
5CDS-5UTRENST00000369327ENST00000461137MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
5CDS-5UTRENST00000369329ENST00000461137MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
5CDS-5UTRENST00000369332ENST00000461137MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
In-frameENST00000369325ENST00000257766MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
In-frameENST00000369325ENST00000403245MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
In-frameENST00000369327ENST00000257766MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
In-frameENST00000369327ENST00000403245MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
In-frameENST00000369329ENST00000257766MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
In-frameENST00000369329ENST00000403245MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
In-frameENST00000369332ENST00000257766MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
In-frameENST00000369332ENST00000403245MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
intron-3CDSENST00000369320ENST00000257766MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
intron-3CDSENST00000369320ENST00000403245MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
intron-3CDSENST00000479630ENST00000257766MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
intron-3CDSENST00000479630ENST00000403245MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
intron-5UTRENST00000369320ENST00000461137MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-
intron-5UTRENST00000479630ENST00000461137MAP3K7chr6

91296482

-KIAA1009chr6

84872989

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000369325MAP3K7chr691296482-ENST00000257766KIAA1009chr684872989-277612001946648
ENST00000369325MAP3K7chr691296482-ENST00000403245KIAA1009chr684872989-277612001946648
ENST00000369327MAP3K7chr691296482-ENST00000257766KIAA1009chr684872989-278212661952648
ENST00000369327MAP3K7chr691296482-ENST00000403245KIAA1009chr684872989-278212661952648
ENST00000369332MAP3K7chr691296482-ENST00000257766KIAA1009chr684872989-29382821142108664
ENST00000369332MAP3K7chr691296482-ENST00000403245KIAA1009chr684872989-29382821142108664
ENST00000369329MAP3K7chr691296482-ENST00000257766KIAA1009chr684872989-29382821142108664
ENST00000369329MAP3K7chr691296482-ENST00000403245KIAA1009chr684872989-29382821142108664

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000369325ENST00000257766MAP3K7chr691296482-KIAA1009chr684872989-0.0007736220.99922633
ENST00000369325ENST00000403245MAP3K7chr691296482-KIAA1009chr684872989-0.0007736220.99922633
ENST00000369327ENST00000257766MAP3K7chr691296482-KIAA1009chr684872989-0.0007772980.99922264
ENST00000369327ENST00000403245MAP3K7chr691296482-KIAA1009chr684872989-0.0007772980.99922264
ENST00000369332ENST00000257766MAP3K7chr691296482-KIAA1009chr684872989-0.0006554210.9993445
ENST00000369332ENST00000403245MAP3K7chr691296482-KIAA1009chr684872989-0.0006554210.9993445
ENST00000369329ENST00000257766MAP3K7chr691296482-KIAA1009chr684872989-0.0006554210.9993445
ENST00000369329ENST00000403245MAP3K7chr691296482-KIAA1009chr684872989-0.0006554210.9993445

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Fusion Genomic Features for MAP3K7-KIAA1009


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MAP3K7-KIAA1009


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:91296482/chr6:84872989)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MAP3K7

O43318

.
FUNCTION: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK). Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), while nuclear factor-kappa B is activated by IKK. MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1, but not that of NF-kappa-B. Promotes TRIM5 capsid-specific restriction activity. Phosphorylates RIPK1 at 'Ser-321' which positively regulates RIPK1 interaction with RIPK3 to promote necroptosis but negatively regulates RIPK1 kinase activity and its interaction with FADD to mediate apoptosis (By similarity). {ECO:0000250|UniProtKB:Q62073, ECO:0000269|PubMed:10094049, ECO:0000269|PubMed:11460167, ECO:0000269|PubMed:12589052, ECO:0000269|PubMed:16845370, ECO:0000269|PubMed:16893890, ECO:0000269|PubMed:21512573, ECO:0000269|PubMed:8663074, ECO:0000269|PubMed:9079627}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369325-1168_1440519.0Compositional biasNote=Poly-Ser
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369327-1158_1440492.0Compositional biasNote=Poly-Ser
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369329-1178_1440607.0Compositional biasNote=Poly-Ser
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369332-1168_1440580.0Compositional biasNote=Poly-Ser
TgeneKIAA1009chr6:91296482chr6:84872989ENST0000025776617271171_12067191328.0Coiled coilOntology_term=ECO:0000255
TgeneKIAA1009chr6:91296482chr6:84872989ENST0000025776617271235_13867191328.0Coiled coilOntology_term=ECO:0000255
TgeneKIAA1009chr6:91296482chr6:84872989ENST0000040324517271171_12067951404.0Coiled coilOntology_term=ECO:0000255
TgeneKIAA1009chr6:91296482chr6:84872989ENST0000040324517271235_13867951404.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369325-11636_29140519.0DomainProtein kinase
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369327-11536_29140492.0DomainProtein kinase
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369329-11736_29140607.0DomainProtein kinase
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369332-11636_29140580.0DomainProtein kinase
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369325-11642_5040519.0Nucleotide bindingATP
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369327-11542_5040492.0Nucleotide bindingATP
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369329-11742_5040607.0Nucleotide bindingATP
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369332-11642_5040580.0Nucleotide bindingATP
TgeneKIAA1009chr6:91296482chr6:84872989ENST000002577661727617_6707191328.0Coiled coilOntology_term=ECO:0000255
TgeneKIAA1009chr6:91296482chr6:84872989ENST000002577661727698_11217191328.0Coiled coilOntology_term=ECO:0000255
TgeneKIAA1009chr6:91296482chr6:84872989ENST000004032451727617_6707951404.0Coiled coilOntology_term=ECO:0000255
TgeneKIAA1009chr6:91296482chr6:84872989ENST000004032451727698_11217951404.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for MAP3K7-KIAA1009


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>51349_51349_1_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369325_KIAA1009_chr6_84872989_ENST00000257766_length(transcript)=2776nt_BP=120nt
ATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAG
ATCGACTACAAGGAGATCGAGGTGGAAGAGAAAGAAAAAGACAGTTTATTGGAAGACATCAAAAGACTGAAACAAGACAAACAAGCTCTT
GAAGTAGACTTCGAAAAAATGAAGAAAGAGAGGGACCAAGCCAAAGATCAGATTGCTTATGTCACAGGTGAGAAATTATATGAAATAAAA
ATTTTAGAAGAAACACATAAACAAGAAATCAGTCGTCTGCAAAAAAGATTACAGTGGTATGCTGAAAATCAGGAACTTCTGGATAAAGAT
GCACTTCGGCTTAGAGAAGCAAATGAGGAAATTGAGAAGCTCAAACTTGAGATTGAGAAACTGAAAGCTGAATCTGGGAATCCATCTATT
CGGCAGAAGATACGCTTAAAAGATAAAGCAGCAGATGCCAAAAAAATTCAGGATCTGGAGCGACAAGTTAAGGAAATGGAAGGGATTCTG
AAGAGAAGATATCCCAATTCTTTACCTGCTTTAATATTGGCTGCATCAGCAGCTGGTGATACAGTGGATAAAAATACAGTGGAATTTATG
GAGAAAAGGATAAAAAAGCTAGAAGCTGATCTGGAGGGCAAAGATGAAGATGCAAAGAAAAGCCTTCGTACCATGGAACAACAGTTTCAG
AAAATGAAGATTCAGTATGAACAAAGACTAGAGCAGCAGGAGCAGCTACTTGCCTGCAAATTGAATCAACATGACTCTCCCAGAATTAAA
GCCCTAGAGAAGGAACTTGATGACATCAAGGAAGCCCATCAGATCACTGTAAGAAACCTTGAAGCCGAAATAGACGTTCTTAAACATCAG
AATGCTGAATTAGACGTCAAGAAAAATGATAAAGATGATGAAGATTTTCAGTCTATAGAATTCCAGGTGGAACAGGCTCATGCTAAAGCT
AAATTAGTAAGACTCAATGAAGAACTGGCTGCAAAAAAGAGAGAAATACAAGACCTCTCAAAAACTGTGGAGAGGCTTCAGAAAGACAGA
AGAATGATGCTATCAAATCAGAACTCAAAGGGCAGAGAGGAAATGTCTGCCAAAAGGGCAAAGAAAGATGTTTTGCACTCAAGTAAAGGA
AATGCTAACTCCTTCCCTGGAACCCTGGACAGCAAGCTGTACCAACCACATACTTTCACTGATTCCCATGTTTCAGAAGTTTTACAAGAA
AACTACAGATTAAAAAATGAGCTAGAAGGATTAATTTCAGAGAAGAATGAACTGAAGATGAAATCTGAAGCAGTGATGAATCAATTTGAA
AACTCCATGAGAAGGGTCAAGGAAGATACTGCAGCACACATTGCATCCCTCAAAGCATCTCATCAGAGAGAAATAGAGAAACTCCTTTGC
CAAAATGCAGTAGAAAATTCTTCTTCCAAAGTAGCTGAACTAAATCGTAAAATAGCAACTCAAGAGGTACTTATAAGACATTTCCAAAGT
CAAGTTAATGAGCTGCAGAGTAAACAAGAGTCTCTCGTAGTTTCTGAAGTTCGAGAAGAAATTCTACAGAAAGAGATTACAAAACTCTTA
GAAGAATTGAGAGAAGCCAAAGAAAACCATACACCAGAGATGAAACATTTCGTGGGCTTAGAAAAGAAAATTAAGCAGATGGAAATGAGA
CATGCACAAAGAGAACAGGAACTTCAACAGATAATACAGCAAACACACCAAGTAGTAGAAACTGAGCAAAACAAAGAAGTTGAAAAATGG
AAAAGACTGGCACAGTTAAAGAATCGTGAGCTGGAGAAGTTCCGCACAGAACTAGACTCAATATTAGATGTTCTCCGAGAGCTGCACCGG
CAAGGAGTGGTTGTGCCAGTTGCTTTTGCAGATGAAATGAATGCACCAGAGTATTAATAGAAATTCAGATTTCATAATGACCTTATTAAA
AGGCCTGAAGATGGATGGGATTGTGCCACTGTCAGGACAGCTTATGAAAAACAAGTGTTCCAATATGTTTCCAGAAAGCAAACAACCAAA
GCAACATTTCAAAATAAATTGCCTTTAACCAATAAGAAAAAAAACATATAATGGTGTATTTTACTAAAAATCATTAACCAGTCTCATTTT
AAGTGATTTATGGACAGTTTCCTTTATAGCAGAGAAGGGCTCACTTGTATGCTAGAAATAGAAAGAAAAGAAAATTGAACATACTCCGCC
ACATTTTTATTGATAATGTGAGGTTTTTAAAATTTTTATTTTAGATCCAGGGGGTACATGTGCTTGTTGTAACATGGGTGTATTGAATAA
TGGTGGGAATTGGGCTTCTAGTGTACCCATCATCCAAATATTAAACACTGTACCCAACAGGTAATTTTTCAACGCTTACTGCCGCTCACA
CTCTTTCCCCTATTGGAGTCCCCAGTGTCTGTTATCTCCATCTTTATGTCTCTGTGTACCCATTGTTTAGCTCCTACTTTTAAGTGAGAA
TATATGCAATATTTTATTTTTTATGTCTGATTTAGTTCACATAGGATAATGGCCTCCAGCTCTATCCATGTTGCTGCAAATGACATGATT
TCATTCTTTTTTATAGTTGCATAATACTCCATTTATATATCTCTCTCTATATATATCTCACGTTTTCTTTATCCAGTCAATTGTTGGTAG

>51349_51349_1_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369325_KIAA1009_chr6_84872989_ENST00000257766_length(amino acids)=648AA_BP=40
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIK
ILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGIL
KRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIK
ALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDR
RMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFE
NSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLL
EELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHR

--------------------------------------------------------------
>51349_51349_2_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369325_KIAA1009_chr6_84872989_ENST00000403245_length(transcript)=2776nt_BP=120nt
ATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAG
ATCGACTACAAGGAGATCGAGGTGGAAGAGAAAGAAAAAGACAGTTTATTGGAAGACATCAAAAGACTGAAACAAGACAAACAAGCTCTT
GAAGTAGACTTCGAAAAAATGAAGAAAGAGAGGGACCAAGCCAAAGATCAGATTGCTTATGTCACAGGTGAGAAATTATATGAAATAAAA
ATTTTAGAAGAAACACATAAACAAGAAATCAGTCGTCTGCAAAAAAGATTACAGTGGTATGCTGAAAATCAGGAACTTCTGGATAAAGAT
GCACTTCGGCTTAGAGAAGCAAATGAGGAAATTGAGAAGCTCAAACTTGAGATTGAGAAACTGAAAGCTGAATCTGGGAATCCATCTATT
CGGCAGAAGATACGCTTAAAAGATAAAGCAGCAGATGCCAAAAAAATTCAGGATCTGGAGCGACAAGTTAAGGAAATGGAAGGGATTCTG
AAGAGAAGATATCCCAATTCTTTACCTGCTTTAATATTGGCTGCATCAGCAGCTGGTGATACAGTGGATAAAAATACAGTGGAATTTATG
GAGAAAAGGATAAAAAAGCTAGAAGCTGATCTGGAGGGCAAAGATGAAGATGCAAAGAAAAGCCTTCGTACCATGGAACAACAGTTTCAG
AAAATGAAGATTCAGTATGAACAAAGACTAGAGCAGCAGGAGCAGCTACTTGCCTGCAAATTGAATCAACATGACTCTCCCAGAATTAAA
GCCCTAGAGAAGGAACTTGATGACATCAAGGAAGCCCATCAGATCACTGTAAGAAACCTTGAAGCCGAAATAGACGTTCTTAAACATCAG
AATGCTGAATTAGACGTCAAGAAAAATGATAAAGATGATGAAGATTTTCAGTCTATAGAATTCCAGGTGGAACAGGCTCATGCTAAAGCT
AAATTAGTAAGACTCAATGAAGAACTGGCTGCAAAAAAGAGAGAAATACAAGACCTCTCAAAAACTGTGGAGAGGCTTCAGAAAGACAGA
AGAATGATGCTATCAAATCAGAACTCAAAGGGCAGAGAGGAAATGTCTGCCAAAAGGGCAAAGAAAGATGTTTTGCACTCAAGTAAAGGA
AATGCTAACTCCTTCCCTGGAACCCTGGACAGCAAGCTGTACCAACCACATACTTTCACTGATTCCCATGTTTCAGAAGTTTTACAAGAA
AACTACAGATTAAAAAATGAGCTAGAAGGATTAATTTCAGAGAAGAATGAACTGAAGATGAAATCTGAAGCAGTGATGAATCAATTTGAA
AACTCCATGAGAAGGGTCAAGGAAGATACTGCAGCACACATTGCATCCCTCAAAGCATCTCATCAGAGAGAAATAGAGAAACTCCTTTGC
CAAAATGCAGTAGAAAATTCTTCTTCCAAAGTAGCTGAACTAAATCGTAAAATAGCAACTCAAGAGGTACTTATAAGACATTTCCAAAGT
CAAGTTAATGAGCTGCAGAGTAAACAAGAGTCTCTCGTAGTTTCTGAAGTTCGAGAAGAAATTCTACAGAAAGAGATTACAAAACTCTTA
GAAGAATTGAGAGAAGCCAAAGAAAACCATACACCAGAGATGAAACATTTCGTGGGCTTAGAAAAGAAAATTAAGCAGATGGAAATGAGA
CATGCACAAAGAGAACAGGAACTTCAACAGATAATACAGCAAACACACCAAGTAGTAGAAACTGAGCAAAACAAAGAAGTTGAAAAATGG
AAAAGACTGGCACAGTTAAAGAATCGTGAGCTGGAGAAGTTCCGCACAGAACTAGACTCAATATTAGATGTTCTCCGAGAGCTGCACCGG
CAAGGAGTGGTTGTGCCAGTTGCTTTTGCAGATGAAATGAATGCACCAGAGTATTAATAGAAATTCAGATTTCATAATGACCTTATTAAA
AGGCCTGAAGATGGATGGGATTGTGCCACTGTCAGGACAGCTTATGAAAAACAAGTGTTCCAATATGTTTCCAGAAAGCAAACAACCAAA
GCAACATTTCAAAATAAATTGCCTTTAACCAATAAGAAAAAAAACATATAATGGTGTATTTTACTAAAAATCATTAACCAGTCTCATTTT
AAGTGATTTATGGACAGTTTCCTTTATAGCAGAGAAGGGCTCACTTGTATGCTAGAAATAGAAAGAAAAGAAAATTGAACATACTCCGCC
ACATTTTTATTGATAATGTGAGGTTTTTAAAATTTTTATTTTAGATCCAGGGGGTACATGTGCTTGTTGTAACATGGGTGTATTGAATAA
TGGTGGGAATTGGGCTTCTAGTGTACCCATCATCCAAATATTAAACACTGTACCCAACAGGTAATTTTTCAACGCTTACTGCCGCTCACA
CTCTTTCCCCTATTGGAGTCCCCAGTGTCTGTTATCTCCATCTTTATGTCTCTGTGTACCCATTGTTTAGCTCCTACTTTTAAGTGAGAA
TATATGCAATATTTTATTTTTTATGTCTGATTTAGTTCACATAGGATAATGGCCTCCAGCTCTATCCATGTTGCTGCAAATGACATGATT
TCATTCTTTTTTATAGTTGCATAATACTCCATTTATATATCTCTCTCTATATATATCTCACGTTTTCTTTATCCAGTCAATTGTTGGTAG

>51349_51349_2_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369325_KIAA1009_chr6_84872989_ENST00000403245_length(amino acids)=648AA_BP=40
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIK
ILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGIL
KRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIK
ALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDR
RMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFE
NSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLL
EELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHR

--------------------------------------------------------------
>51349_51349_3_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369327_KIAA1009_chr6_84872989_ENST00000257766_length(transcript)=2782nt_BP=126nt
GGGATCATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTT
GAAGAGATCGACTACAAGGAGATCGAGGTGGAAGAGAAAGAAAAAGACAGTTTATTGGAAGACATCAAAAGACTGAAACAAGACAAACAA
GCTCTTGAAGTAGACTTCGAAAAAATGAAGAAAGAGAGGGACCAAGCCAAAGATCAGATTGCTTATGTCACAGGTGAGAAATTATATGAA
ATAAAAATTTTAGAAGAAACACATAAACAAGAAATCAGTCGTCTGCAAAAAAGATTACAGTGGTATGCTGAAAATCAGGAACTTCTGGAT
AAAGATGCACTTCGGCTTAGAGAAGCAAATGAGGAAATTGAGAAGCTCAAACTTGAGATTGAGAAACTGAAAGCTGAATCTGGGAATCCA
TCTATTCGGCAGAAGATACGCTTAAAAGATAAAGCAGCAGATGCCAAAAAAATTCAGGATCTGGAGCGACAAGTTAAGGAAATGGAAGGG
ATTCTGAAGAGAAGATATCCCAATTCTTTACCTGCTTTAATATTGGCTGCATCAGCAGCTGGTGATACAGTGGATAAAAATACAGTGGAA
TTTATGGAGAAAAGGATAAAAAAGCTAGAAGCTGATCTGGAGGGCAAAGATGAAGATGCAAAGAAAAGCCTTCGTACCATGGAACAACAG
TTTCAGAAAATGAAGATTCAGTATGAACAAAGACTAGAGCAGCAGGAGCAGCTACTTGCCTGCAAATTGAATCAACATGACTCTCCCAGA
ATTAAAGCCCTAGAGAAGGAACTTGATGACATCAAGGAAGCCCATCAGATCACTGTAAGAAACCTTGAAGCCGAAATAGACGTTCTTAAA
CATCAGAATGCTGAATTAGACGTCAAGAAAAATGATAAAGATGATGAAGATTTTCAGTCTATAGAATTCCAGGTGGAACAGGCTCATGCT
AAAGCTAAATTAGTAAGACTCAATGAAGAACTGGCTGCAAAAAAGAGAGAAATACAAGACCTCTCAAAAACTGTGGAGAGGCTTCAGAAA
GACAGAAGAATGATGCTATCAAATCAGAACTCAAAGGGCAGAGAGGAAATGTCTGCCAAAAGGGCAAAGAAAGATGTTTTGCACTCAAGT
AAAGGAAATGCTAACTCCTTCCCTGGAACCCTGGACAGCAAGCTGTACCAACCACATACTTTCACTGATTCCCATGTTTCAGAAGTTTTA
CAAGAAAACTACAGATTAAAAAATGAGCTAGAAGGATTAATTTCAGAGAAGAATGAACTGAAGATGAAATCTGAAGCAGTGATGAATCAA
TTTGAAAACTCCATGAGAAGGGTCAAGGAAGATACTGCAGCACACATTGCATCCCTCAAAGCATCTCATCAGAGAGAAATAGAGAAACTC
CTTTGCCAAAATGCAGTAGAAAATTCTTCTTCCAAAGTAGCTGAACTAAATCGTAAAATAGCAACTCAAGAGGTACTTATAAGACATTTC
CAAAGTCAAGTTAATGAGCTGCAGAGTAAACAAGAGTCTCTCGTAGTTTCTGAAGTTCGAGAAGAAATTCTACAGAAAGAGATTACAAAA
CTCTTAGAAGAATTGAGAGAAGCCAAAGAAAACCATACACCAGAGATGAAACATTTCGTGGGCTTAGAAAAGAAAATTAAGCAGATGGAA
ATGAGACATGCACAAAGAGAACAGGAACTTCAACAGATAATACAGCAAACACACCAAGTAGTAGAAACTGAGCAAAACAAAGAAGTTGAA
AAATGGAAAAGACTGGCACAGTTAAAGAATCGTGAGCTGGAGAAGTTCCGCACAGAACTAGACTCAATATTAGATGTTCTCCGAGAGCTG
CACCGGCAAGGAGTGGTTGTGCCAGTTGCTTTTGCAGATGAAATGAATGCACCAGAGTATTAATAGAAATTCAGATTTCATAATGACCTT
ATTAAAAGGCCTGAAGATGGATGGGATTGTGCCACTGTCAGGACAGCTTATGAAAAACAAGTGTTCCAATATGTTTCCAGAAAGCAAACA
ACCAAAGCAACATTTCAAAATAAATTGCCTTTAACCAATAAGAAAAAAAACATATAATGGTGTATTTTACTAAAAATCATTAACCAGTCT
CATTTTAAGTGATTTATGGACAGTTTCCTTTATAGCAGAGAAGGGCTCACTTGTATGCTAGAAATAGAAAGAAAAGAAAATTGAACATAC
TCCGCCACATTTTTATTGATAATGTGAGGTTTTTAAAATTTTTATTTTAGATCCAGGGGGTACATGTGCTTGTTGTAACATGGGTGTATT
GAATAATGGTGGGAATTGGGCTTCTAGTGTACCCATCATCCAAATATTAAACACTGTACCCAACAGGTAATTTTTCAACGCTTACTGCCG
CTCACACTCTTTCCCCTATTGGAGTCCCCAGTGTCTGTTATCTCCATCTTTATGTCTCTGTGTACCCATTGTTTAGCTCCTACTTTTAAG
TGAGAATATATGCAATATTTTATTTTTTATGTCTGATTTAGTTCACATAGGATAATGGCCTCCAGCTCTATCCATGTTGCTGCAAATGAC
ATGATTTCATTCTTTTTTATAGTTGCATAATACTCCATTTATATATCTCTCTCTATATATATCTCACGTTTTCTTTATCCAGTCAATTGT

>51349_51349_3_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369327_KIAA1009_chr6_84872989_ENST00000257766_length(amino acids)=648AA_BP=40
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIK
ILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGIL
KRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIK
ALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDR
RMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFE
NSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLL
EELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHR

--------------------------------------------------------------
>51349_51349_4_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369327_KIAA1009_chr6_84872989_ENST00000403245_length(transcript)=2782nt_BP=126nt
GGGATCATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTT
GAAGAGATCGACTACAAGGAGATCGAGGTGGAAGAGAAAGAAAAAGACAGTTTATTGGAAGACATCAAAAGACTGAAACAAGACAAACAA
GCTCTTGAAGTAGACTTCGAAAAAATGAAGAAAGAGAGGGACCAAGCCAAAGATCAGATTGCTTATGTCACAGGTGAGAAATTATATGAA
ATAAAAATTTTAGAAGAAACACATAAACAAGAAATCAGTCGTCTGCAAAAAAGATTACAGTGGTATGCTGAAAATCAGGAACTTCTGGAT
AAAGATGCACTTCGGCTTAGAGAAGCAAATGAGGAAATTGAGAAGCTCAAACTTGAGATTGAGAAACTGAAAGCTGAATCTGGGAATCCA
TCTATTCGGCAGAAGATACGCTTAAAAGATAAAGCAGCAGATGCCAAAAAAATTCAGGATCTGGAGCGACAAGTTAAGGAAATGGAAGGG
ATTCTGAAGAGAAGATATCCCAATTCTTTACCTGCTTTAATATTGGCTGCATCAGCAGCTGGTGATACAGTGGATAAAAATACAGTGGAA
TTTATGGAGAAAAGGATAAAAAAGCTAGAAGCTGATCTGGAGGGCAAAGATGAAGATGCAAAGAAAAGCCTTCGTACCATGGAACAACAG
TTTCAGAAAATGAAGATTCAGTATGAACAAAGACTAGAGCAGCAGGAGCAGCTACTTGCCTGCAAATTGAATCAACATGACTCTCCCAGA
ATTAAAGCCCTAGAGAAGGAACTTGATGACATCAAGGAAGCCCATCAGATCACTGTAAGAAACCTTGAAGCCGAAATAGACGTTCTTAAA
CATCAGAATGCTGAATTAGACGTCAAGAAAAATGATAAAGATGATGAAGATTTTCAGTCTATAGAATTCCAGGTGGAACAGGCTCATGCT
AAAGCTAAATTAGTAAGACTCAATGAAGAACTGGCTGCAAAAAAGAGAGAAATACAAGACCTCTCAAAAACTGTGGAGAGGCTTCAGAAA
GACAGAAGAATGATGCTATCAAATCAGAACTCAAAGGGCAGAGAGGAAATGTCTGCCAAAAGGGCAAAGAAAGATGTTTTGCACTCAAGT
AAAGGAAATGCTAACTCCTTCCCTGGAACCCTGGACAGCAAGCTGTACCAACCACATACTTTCACTGATTCCCATGTTTCAGAAGTTTTA
CAAGAAAACTACAGATTAAAAAATGAGCTAGAAGGATTAATTTCAGAGAAGAATGAACTGAAGATGAAATCTGAAGCAGTGATGAATCAA
TTTGAAAACTCCATGAGAAGGGTCAAGGAAGATACTGCAGCACACATTGCATCCCTCAAAGCATCTCATCAGAGAGAAATAGAGAAACTC
CTTTGCCAAAATGCAGTAGAAAATTCTTCTTCCAAAGTAGCTGAACTAAATCGTAAAATAGCAACTCAAGAGGTACTTATAAGACATTTC
CAAAGTCAAGTTAATGAGCTGCAGAGTAAACAAGAGTCTCTCGTAGTTTCTGAAGTTCGAGAAGAAATTCTACAGAAAGAGATTACAAAA
CTCTTAGAAGAATTGAGAGAAGCCAAAGAAAACCATACACCAGAGATGAAACATTTCGTGGGCTTAGAAAAGAAAATTAAGCAGATGGAA
ATGAGACATGCACAAAGAGAACAGGAACTTCAACAGATAATACAGCAAACACACCAAGTAGTAGAAACTGAGCAAAACAAAGAAGTTGAA
AAATGGAAAAGACTGGCACAGTTAAAGAATCGTGAGCTGGAGAAGTTCCGCACAGAACTAGACTCAATATTAGATGTTCTCCGAGAGCTG
CACCGGCAAGGAGTGGTTGTGCCAGTTGCTTTTGCAGATGAAATGAATGCACCAGAGTATTAATAGAAATTCAGATTTCATAATGACCTT
ATTAAAAGGCCTGAAGATGGATGGGATTGTGCCACTGTCAGGACAGCTTATGAAAAACAAGTGTTCCAATATGTTTCCAGAAAGCAAACA
ACCAAAGCAACATTTCAAAATAAATTGCCTTTAACCAATAAGAAAAAAAACATATAATGGTGTATTTTACTAAAAATCATTAACCAGTCT
CATTTTAAGTGATTTATGGACAGTTTCCTTTATAGCAGAGAAGGGCTCACTTGTATGCTAGAAATAGAAAGAAAAGAAAATTGAACATAC
TCCGCCACATTTTTATTGATAATGTGAGGTTTTTAAAATTTTTATTTTAGATCCAGGGGGTACATGTGCTTGTTGTAACATGGGTGTATT
GAATAATGGTGGGAATTGGGCTTCTAGTGTACCCATCATCCAAATATTAAACACTGTACCCAACAGGTAATTTTTCAACGCTTACTGCCG
CTCACACTCTTTCCCCTATTGGAGTCCCCAGTGTCTGTTATCTCCATCTTTATGTCTCTGTGTACCCATTGTTTAGCTCCTACTTTTAAG
TGAGAATATATGCAATATTTTATTTTTTATGTCTGATTTAGTTCACATAGGATAATGGCCTCCAGCTCTATCCATGTTGCTGCAAATGAC
ATGATTTCATTCTTTTTTATAGTTGCATAATACTCCATTTATATATCTCTCTCTATATATATCTCACGTTTTCTTTATCCAGTCAATTGT

>51349_51349_4_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369327_KIAA1009_chr6_84872989_ENST00000403245_length(amino acids)=648AA_BP=40
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIK
ILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGIL
KRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLNQHDSPRIK
ALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDR
RMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFE
NSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLL
EELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHR

--------------------------------------------------------------
>51349_51349_5_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369329_KIAA1009_chr6_84872989_ENST00000257766_length(transcript)=2938nt_BP=282nt
GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC
GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC
GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC
GAGGTGGAAGAGAAAGAAAAAGACAGTTTATTGGAAGACATCAAAAGACTGAAACAAGACAAACAAGCTCTTGAAGTAGACTTCGAAAAA
ATGAAGAAAGAGAGGGACCAAGCCAAAGATCAGATTGCTTATGTCACAGGTGAGAAATTATATGAAATAAAAATTTTAGAAGAAACACAT
AAACAAGAAATCAGTCGTCTGCAAAAAAGATTACAGTGGTATGCTGAAAATCAGGAACTTCTGGATAAAGATGCACTTCGGCTTAGAGAA
GCAAATGAGGAAATTGAGAAGCTCAAACTTGAGATTGAGAAACTGAAAGCTGAATCTGGGAATCCATCTATTCGGCAGAAGATACGCTTA
AAAGATAAAGCAGCAGATGCCAAAAAAATTCAGGATCTGGAGCGACAAGTTAAGGAAATGGAAGGGATTCTGAAGAGAAGATATCCCAAT
TCTTTACCTGCTTTAATATTGGCTGCATCAGCAGCTGGTGATACAGTGGATAAAAATACAGTGGAATTTATGGAGAAAAGGATAAAAAAG
CTAGAAGCTGATCTGGAGGGCAAAGATGAAGATGCAAAGAAAAGCCTTCGTACCATGGAACAACAGTTTCAGAAAATGAAGATTCAGTAT
GAACAAAGACTAGAGCAGCAGGAGCAGCTACTTGCCTGCAAATTGAATCAACATGACTCTCCCAGAATTAAAGCCCTAGAGAAGGAACTT
GATGACATCAAGGAAGCCCATCAGATCACTGTAAGAAACCTTGAAGCCGAAATAGACGTTCTTAAACATCAGAATGCTGAATTAGACGTC
AAGAAAAATGATAAAGATGATGAAGATTTTCAGTCTATAGAATTCCAGGTGGAACAGGCTCATGCTAAAGCTAAATTAGTAAGACTCAAT
GAAGAACTGGCTGCAAAAAAGAGAGAAATACAAGACCTCTCAAAAACTGTGGAGAGGCTTCAGAAAGACAGAAGAATGATGCTATCAAAT
CAGAACTCAAAGGGCAGAGAGGAAATGTCTGCCAAAAGGGCAAAGAAAGATGTTTTGCACTCAAGTAAAGGAAATGCTAACTCCTTCCCT
GGAACCCTGGACAGCAAGCTGTACCAACCACATACTTTCACTGATTCCCATGTTTCAGAAGTTTTACAAGAAAACTACAGATTAAAAAAT
GAGCTAGAAGGATTAATTTCAGAGAAGAATGAACTGAAGATGAAATCTGAAGCAGTGATGAATCAATTTGAAAACTCCATGAGAAGGGTC
AAGGAAGATACTGCAGCACACATTGCATCCCTCAAAGCATCTCATCAGAGAGAAATAGAGAAACTCCTTTGCCAAAATGCAGTAGAAAAT
TCTTCTTCCAAAGTAGCTGAACTAAATCGTAAAATAGCAACTCAAGAGGTACTTATAAGACATTTCCAAAGTCAAGTTAATGAGCTGCAG
AGTAAACAAGAGTCTCTCGTAGTTTCTGAAGTTCGAGAAGAAATTCTACAGAAAGAGATTACAAAACTCTTAGAAGAATTGAGAGAAGCC
AAAGAAAACCATACACCAGAGATGAAACATTTCGTGGGCTTAGAAAAGAAAATTAAGCAGATGGAAATGAGACATGCACAAAGAGAACAG
GAACTTCAACAGATAATACAGCAAACACACCAAGTAGTAGAAACTGAGCAAAACAAAGAAGTTGAAAAATGGAAAAGACTGGCACAGTTA
AAGAATCGTGAGCTGGAGAAGTTCCGCACAGAACTAGACTCAATATTAGATGTTCTCCGAGAGCTGCACCGGCAAGGAGTGGTTGTGCCA
GTTGCTTTTGCAGATGAAATGAATGCACCAGAGTATTAATAGAAATTCAGATTTCATAATGACCTTATTAAAAGGCCTGAAGATGGATGG
GATTGTGCCACTGTCAGGACAGCTTATGAAAAACAAGTGTTCCAATATGTTTCCAGAAAGCAAACAACCAAAGCAACATTTCAAAATAAA
TTGCCTTTAACCAATAAGAAAAAAAACATATAATGGTGTATTTTACTAAAAATCATTAACCAGTCTCATTTTAAGTGATTTATGGACAGT
TTCCTTTATAGCAGAGAAGGGCTCACTTGTATGCTAGAAATAGAAAGAAAAGAAAATTGAACATACTCCGCCACATTTTTATTGATAATG
TGAGGTTTTTAAAATTTTTATTTTAGATCCAGGGGGTACATGTGCTTGTTGTAACATGGGTGTATTGAATAATGGTGGGAATTGGGCTTC
TAGTGTACCCATCATCCAAATATTAAACACTGTACCCAACAGGTAATTTTTCAACGCTTACTGCCGCTCACACTCTTTCCCCTATTGGAG
TCCCCAGTGTCTGTTATCTCCATCTTTATGTCTCTGTGTACCCATTGTTTAGCTCCTACTTTTAAGTGAGAATATATGCAATATTTTATT
TTTTATGTCTGATTTAGTTCACATAGGATAATGGCCTCCAGCTCTATCCATGTTGCTGCAAATGACATGATTTCATTCTTTTTTATAGTT
GCATAATACTCCATTTATATATCTCTCTCTATATATATCTCACGTTTTCTTTATCCAGTCAATTGTTGGTAGATACTTAGGTTGGTTCCA

>51349_51349_5_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369329_KIAA1009_chr6_84872989_ENST00000257766_length(amino acids)=664AA_BP=56
MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQA
KDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAK
KIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQE
QLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKR
EIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISE
KNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVV
SEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKF

--------------------------------------------------------------
>51349_51349_6_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369329_KIAA1009_chr6_84872989_ENST00000403245_length(transcript)=2938nt_BP=282nt
GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC
GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC
GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC
GAGGTGGAAGAGAAAGAAAAAGACAGTTTATTGGAAGACATCAAAAGACTGAAACAAGACAAACAAGCTCTTGAAGTAGACTTCGAAAAA
ATGAAGAAAGAGAGGGACCAAGCCAAAGATCAGATTGCTTATGTCACAGGTGAGAAATTATATGAAATAAAAATTTTAGAAGAAACACAT
AAACAAGAAATCAGTCGTCTGCAAAAAAGATTACAGTGGTATGCTGAAAATCAGGAACTTCTGGATAAAGATGCACTTCGGCTTAGAGAA
GCAAATGAGGAAATTGAGAAGCTCAAACTTGAGATTGAGAAACTGAAAGCTGAATCTGGGAATCCATCTATTCGGCAGAAGATACGCTTA
AAAGATAAAGCAGCAGATGCCAAAAAAATTCAGGATCTGGAGCGACAAGTTAAGGAAATGGAAGGGATTCTGAAGAGAAGATATCCCAAT
TCTTTACCTGCTTTAATATTGGCTGCATCAGCAGCTGGTGATACAGTGGATAAAAATACAGTGGAATTTATGGAGAAAAGGATAAAAAAG
CTAGAAGCTGATCTGGAGGGCAAAGATGAAGATGCAAAGAAAAGCCTTCGTACCATGGAACAACAGTTTCAGAAAATGAAGATTCAGTAT
GAACAAAGACTAGAGCAGCAGGAGCAGCTACTTGCCTGCAAATTGAATCAACATGACTCTCCCAGAATTAAAGCCCTAGAGAAGGAACTT
GATGACATCAAGGAAGCCCATCAGATCACTGTAAGAAACCTTGAAGCCGAAATAGACGTTCTTAAACATCAGAATGCTGAATTAGACGTC
AAGAAAAATGATAAAGATGATGAAGATTTTCAGTCTATAGAATTCCAGGTGGAACAGGCTCATGCTAAAGCTAAATTAGTAAGACTCAAT
GAAGAACTGGCTGCAAAAAAGAGAGAAATACAAGACCTCTCAAAAACTGTGGAGAGGCTTCAGAAAGACAGAAGAATGATGCTATCAAAT
CAGAACTCAAAGGGCAGAGAGGAAATGTCTGCCAAAAGGGCAAAGAAAGATGTTTTGCACTCAAGTAAAGGAAATGCTAACTCCTTCCCT
GGAACCCTGGACAGCAAGCTGTACCAACCACATACTTTCACTGATTCCCATGTTTCAGAAGTTTTACAAGAAAACTACAGATTAAAAAAT
GAGCTAGAAGGATTAATTTCAGAGAAGAATGAACTGAAGATGAAATCTGAAGCAGTGATGAATCAATTTGAAAACTCCATGAGAAGGGTC
AAGGAAGATACTGCAGCACACATTGCATCCCTCAAAGCATCTCATCAGAGAGAAATAGAGAAACTCCTTTGCCAAAATGCAGTAGAAAAT
TCTTCTTCCAAAGTAGCTGAACTAAATCGTAAAATAGCAACTCAAGAGGTACTTATAAGACATTTCCAAAGTCAAGTTAATGAGCTGCAG
AGTAAACAAGAGTCTCTCGTAGTTTCTGAAGTTCGAGAAGAAATTCTACAGAAAGAGATTACAAAACTCTTAGAAGAATTGAGAGAAGCC
AAAGAAAACCATACACCAGAGATGAAACATTTCGTGGGCTTAGAAAAGAAAATTAAGCAGATGGAAATGAGACATGCACAAAGAGAACAG
GAACTTCAACAGATAATACAGCAAACACACCAAGTAGTAGAAACTGAGCAAAACAAAGAAGTTGAAAAATGGAAAAGACTGGCACAGTTA
AAGAATCGTGAGCTGGAGAAGTTCCGCACAGAACTAGACTCAATATTAGATGTTCTCCGAGAGCTGCACCGGCAAGGAGTGGTTGTGCCA
GTTGCTTTTGCAGATGAAATGAATGCACCAGAGTATTAATAGAAATTCAGATTTCATAATGACCTTATTAAAAGGCCTGAAGATGGATGG
GATTGTGCCACTGTCAGGACAGCTTATGAAAAACAAGTGTTCCAATATGTTTCCAGAAAGCAAACAACCAAAGCAACATTTCAAAATAAA
TTGCCTTTAACCAATAAGAAAAAAAACATATAATGGTGTATTTTACTAAAAATCATTAACCAGTCTCATTTTAAGTGATTTATGGACAGT
TTCCTTTATAGCAGAGAAGGGCTCACTTGTATGCTAGAAATAGAAAGAAAAGAAAATTGAACATACTCCGCCACATTTTTATTGATAATG
TGAGGTTTTTAAAATTTTTATTTTAGATCCAGGGGGTACATGTGCTTGTTGTAACATGGGTGTATTGAATAATGGTGGGAATTGGGCTTC
TAGTGTACCCATCATCCAAATATTAAACACTGTACCCAACAGGTAATTTTTCAACGCTTACTGCCGCTCACACTCTTTCCCCTATTGGAG
TCCCCAGTGTCTGTTATCTCCATCTTTATGTCTCTGTGTACCCATTGTTTAGCTCCTACTTTTAAGTGAGAATATATGCAATATTTTATT
TTTTATGTCTGATTTAGTTCACATAGGATAATGGCCTCCAGCTCTATCCATGTTGCTGCAAATGACATGATTTCATTCTTTTTTATAGTT
GCATAATACTCCATTTATATATCTCTCTCTATATATATCTCACGTTTTCTTTATCCAGTCAATTGTTGGTAGATACTTAGGTTGGTTCCA

>51349_51349_6_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369329_KIAA1009_chr6_84872989_ENST00000403245_length(amino acids)=664AA_BP=56
MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQA
KDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAK
KIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQE
QLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKR
EIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISE
KNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVV
SEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKF

--------------------------------------------------------------
>51349_51349_7_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369332_KIAA1009_chr6_84872989_ENST00000257766_length(transcript)=2938nt_BP=282nt
GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC
GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC
GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC
GAGGTGGAAGAGAAAGAAAAAGACAGTTTATTGGAAGACATCAAAAGACTGAAACAAGACAAACAAGCTCTTGAAGTAGACTTCGAAAAA
ATGAAGAAAGAGAGGGACCAAGCCAAAGATCAGATTGCTTATGTCACAGGTGAGAAATTATATGAAATAAAAATTTTAGAAGAAACACAT
AAACAAGAAATCAGTCGTCTGCAAAAAAGATTACAGTGGTATGCTGAAAATCAGGAACTTCTGGATAAAGATGCACTTCGGCTTAGAGAA
GCAAATGAGGAAATTGAGAAGCTCAAACTTGAGATTGAGAAACTGAAAGCTGAATCTGGGAATCCATCTATTCGGCAGAAGATACGCTTA
AAAGATAAAGCAGCAGATGCCAAAAAAATTCAGGATCTGGAGCGACAAGTTAAGGAAATGGAAGGGATTCTGAAGAGAAGATATCCCAAT
TCTTTACCTGCTTTAATATTGGCTGCATCAGCAGCTGGTGATACAGTGGATAAAAATACAGTGGAATTTATGGAGAAAAGGATAAAAAAG
CTAGAAGCTGATCTGGAGGGCAAAGATGAAGATGCAAAGAAAAGCCTTCGTACCATGGAACAACAGTTTCAGAAAATGAAGATTCAGTAT
GAACAAAGACTAGAGCAGCAGGAGCAGCTACTTGCCTGCAAATTGAATCAACATGACTCTCCCAGAATTAAAGCCCTAGAGAAGGAACTT
GATGACATCAAGGAAGCCCATCAGATCACTGTAAGAAACCTTGAAGCCGAAATAGACGTTCTTAAACATCAGAATGCTGAATTAGACGTC
AAGAAAAATGATAAAGATGATGAAGATTTTCAGTCTATAGAATTCCAGGTGGAACAGGCTCATGCTAAAGCTAAATTAGTAAGACTCAAT
GAAGAACTGGCTGCAAAAAAGAGAGAAATACAAGACCTCTCAAAAACTGTGGAGAGGCTTCAGAAAGACAGAAGAATGATGCTATCAAAT
CAGAACTCAAAGGGCAGAGAGGAAATGTCTGCCAAAAGGGCAAAGAAAGATGTTTTGCACTCAAGTAAAGGAAATGCTAACTCCTTCCCT
GGAACCCTGGACAGCAAGCTGTACCAACCACATACTTTCACTGATTCCCATGTTTCAGAAGTTTTACAAGAAAACTACAGATTAAAAAAT
GAGCTAGAAGGATTAATTTCAGAGAAGAATGAACTGAAGATGAAATCTGAAGCAGTGATGAATCAATTTGAAAACTCCATGAGAAGGGTC
AAGGAAGATACTGCAGCACACATTGCATCCCTCAAAGCATCTCATCAGAGAGAAATAGAGAAACTCCTTTGCCAAAATGCAGTAGAAAAT
TCTTCTTCCAAAGTAGCTGAACTAAATCGTAAAATAGCAACTCAAGAGGTACTTATAAGACATTTCCAAAGTCAAGTTAATGAGCTGCAG
AGTAAACAAGAGTCTCTCGTAGTTTCTGAAGTTCGAGAAGAAATTCTACAGAAAGAGATTACAAAACTCTTAGAAGAATTGAGAGAAGCC
AAAGAAAACCATACACCAGAGATGAAACATTTCGTGGGCTTAGAAAAGAAAATTAAGCAGATGGAAATGAGACATGCACAAAGAGAACAG
GAACTTCAACAGATAATACAGCAAACACACCAAGTAGTAGAAACTGAGCAAAACAAAGAAGTTGAAAAATGGAAAAGACTGGCACAGTTA
AAGAATCGTGAGCTGGAGAAGTTCCGCACAGAACTAGACTCAATATTAGATGTTCTCCGAGAGCTGCACCGGCAAGGAGTGGTTGTGCCA
GTTGCTTTTGCAGATGAAATGAATGCACCAGAGTATTAATAGAAATTCAGATTTCATAATGACCTTATTAAAAGGCCTGAAGATGGATGG
GATTGTGCCACTGTCAGGACAGCTTATGAAAAACAAGTGTTCCAATATGTTTCCAGAAAGCAAACAACCAAAGCAACATTTCAAAATAAA
TTGCCTTTAACCAATAAGAAAAAAAACATATAATGGTGTATTTTACTAAAAATCATTAACCAGTCTCATTTTAAGTGATTTATGGACAGT
TTCCTTTATAGCAGAGAAGGGCTCACTTGTATGCTAGAAATAGAAAGAAAAGAAAATTGAACATACTCCGCCACATTTTTATTGATAATG
TGAGGTTTTTAAAATTTTTATTTTAGATCCAGGGGGTACATGTGCTTGTTGTAACATGGGTGTATTGAATAATGGTGGGAATTGGGCTTC
TAGTGTACCCATCATCCAAATATTAAACACTGTACCCAACAGGTAATTTTTCAACGCTTACTGCCGCTCACACTCTTTCCCCTATTGGAG
TCCCCAGTGTCTGTTATCTCCATCTTTATGTCTCTGTGTACCCATTGTTTAGCTCCTACTTTTAAGTGAGAATATATGCAATATTTTATT
TTTTATGTCTGATTTAGTTCACATAGGATAATGGCCTCCAGCTCTATCCATGTTGCTGCAAATGACATGATTTCATTCTTTTTTATAGTT
GCATAATACTCCATTTATATATCTCTCTCTATATATATCTCACGTTTTCTTTATCCAGTCAATTGTTGGTAGATACTTAGGTTGGTTCCA

>51349_51349_7_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369332_KIAA1009_chr6_84872989_ENST00000257766_length(amino acids)=664AA_BP=56
MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQA
KDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAK
KIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQE
QLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKR
EIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISE
KNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVV
SEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKF

--------------------------------------------------------------
>51349_51349_8_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369332_KIAA1009_chr6_84872989_ENST00000403245_length(transcript)=2938nt_BP=282nt
GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC
GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC
GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC
GAGGTGGAAGAGAAAGAAAAAGACAGTTTATTGGAAGACATCAAAAGACTGAAACAAGACAAACAAGCTCTTGAAGTAGACTTCGAAAAA
ATGAAGAAAGAGAGGGACCAAGCCAAAGATCAGATTGCTTATGTCACAGGTGAGAAATTATATGAAATAAAAATTTTAGAAGAAACACAT
AAACAAGAAATCAGTCGTCTGCAAAAAAGATTACAGTGGTATGCTGAAAATCAGGAACTTCTGGATAAAGATGCACTTCGGCTTAGAGAA
GCAAATGAGGAAATTGAGAAGCTCAAACTTGAGATTGAGAAACTGAAAGCTGAATCTGGGAATCCATCTATTCGGCAGAAGATACGCTTA
AAAGATAAAGCAGCAGATGCCAAAAAAATTCAGGATCTGGAGCGACAAGTTAAGGAAATGGAAGGGATTCTGAAGAGAAGATATCCCAAT
TCTTTACCTGCTTTAATATTGGCTGCATCAGCAGCTGGTGATACAGTGGATAAAAATACAGTGGAATTTATGGAGAAAAGGATAAAAAAG
CTAGAAGCTGATCTGGAGGGCAAAGATGAAGATGCAAAGAAAAGCCTTCGTACCATGGAACAACAGTTTCAGAAAATGAAGATTCAGTAT
GAACAAAGACTAGAGCAGCAGGAGCAGCTACTTGCCTGCAAATTGAATCAACATGACTCTCCCAGAATTAAAGCCCTAGAGAAGGAACTT
GATGACATCAAGGAAGCCCATCAGATCACTGTAAGAAACCTTGAAGCCGAAATAGACGTTCTTAAACATCAGAATGCTGAATTAGACGTC
AAGAAAAATGATAAAGATGATGAAGATTTTCAGTCTATAGAATTCCAGGTGGAACAGGCTCATGCTAAAGCTAAATTAGTAAGACTCAAT
GAAGAACTGGCTGCAAAAAAGAGAGAAATACAAGACCTCTCAAAAACTGTGGAGAGGCTTCAGAAAGACAGAAGAATGATGCTATCAAAT
CAGAACTCAAAGGGCAGAGAGGAAATGTCTGCCAAAAGGGCAAAGAAAGATGTTTTGCACTCAAGTAAAGGAAATGCTAACTCCTTCCCT
GGAACCCTGGACAGCAAGCTGTACCAACCACATACTTTCACTGATTCCCATGTTTCAGAAGTTTTACAAGAAAACTACAGATTAAAAAAT
GAGCTAGAAGGATTAATTTCAGAGAAGAATGAACTGAAGATGAAATCTGAAGCAGTGATGAATCAATTTGAAAACTCCATGAGAAGGGTC
AAGGAAGATACTGCAGCACACATTGCATCCCTCAAAGCATCTCATCAGAGAGAAATAGAGAAACTCCTTTGCCAAAATGCAGTAGAAAAT
TCTTCTTCCAAAGTAGCTGAACTAAATCGTAAAATAGCAACTCAAGAGGTACTTATAAGACATTTCCAAAGTCAAGTTAATGAGCTGCAG
AGTAAACAAGAGTCTCTCGTAGTTTCTGAAGTTCGAGAAGAAATTCTACAGAAAGAGATTACAAAACTCTTAGAAGAATTGAGAGAAGCC
AAAGAAAACCATACACCAGAGATGAAACATTTCGTGGGCTTAGAAAAGAAAATTAAGCAGATGGAAATGAGACATGCACAAAGAGAACAG
GAACTTCAACAGATAATACAGCAAACACACCAAGTAGTAGAAACTGAGCAAAACAAAGAAGTTGAAAAATGGAAAAGACTGGCACAGTTA
AAGAATCGTGAGCTGGAGAAGTTCCGCACAGAACTAGACTCAATATTAGATGTTCTCCGAGAGCTGCACCGGCAAGGAGTGGTTGTGCCA
GTTGCTTTTGCAGATGAAATGAATGCACCAGAGTATTAATAGAAATTCAGATTTCATAATGACCTTATTAAAAGGCCTGAAGATGGATGG
GATTGTGCCACTGTCAGGACAGCTTATGAAAAACAAGTGTTCCAATATGTTTCCAGAAAGCAAACAACCAAAGCAACATTTCAAAATAAA
TTGCCTTTAACCAATAAGAAAAAAAACATATAATGGTGTATTTTACTAAAAATCATTAACCAGTCTCATTTTAAGTGATTTATGGACAGT
TTCCTTTATAGCAGAGAAGGGCTCACTTGTATGCTAGAAATAGAAAGAAAAGAAAATTGAACATACTCCGCCACATTTTTATTGATAATG
TGAGGTTTTTAAAATTTTTATTTTAGATCCAGGGGGTACATGTGCTTGTTGTAACATGGGTGTATTGAATAATGGTGGGAATTGGGCTTC
TAGTGTACCCATCATCCAAATATTAAACACTGTACCCAACAGGTAATTTTTCAACGCTTACTGCCGCTCACACTCTTTCCCCTATTGGAG
TCCCCAGTGTCTGTTATCTCCATCTTTATGTCTCTGTGTACCCATTGTTTAGCTCCTACTTTTAAGTGAGAATATATGCAATATTTTATT
TTTTATGTCTGATTTAGTTCACATAGGATAATGGCCTCCAGCTCTATCCATGTTGCTGCAAATGACATGATTTCATTCTTTTTTATAGTT
GCATAATACTCCATTTATATATCTCTCTCTATATATATCTCACGTTTTCTTTATCCAGTCAATTGTTGGTAGATACTTAGGTTGGTTCCA

>51349_51349_8_MAP3K7-KIAA1009_MAP3K7_chr6_91296482_ENST00000369332_KIAA1009_chr6_84872989_ENST00000403245_length(amino acids)=664AA_BP=56
MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEEKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQA
KDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAK
KIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQE
QLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKR
EIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISE
KNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVV
SEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MAP3K7-KIAA1009


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369325-1161_30040.0519.0MAPK8IP1
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369327-1151_30040.0492.0MAPK8IP1
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369329-1171_30040.0607.0MAPK8IP1
HgeneMAP3K7chr6:91296482chr6:84872989ENST00000369332-1161_30040.0580.0MAPK8IP1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MAP3K7-KIAA1009


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MAP3K7-KIAA1009


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource