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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MAP3K7-SMAP1 (FusionGDB2 ID:51353)

Fusion Gene Summary for MAP3K7-SMAP1

check button Fusion gene summary
Fusion gene informationFusion gene name: MAP3K7-SMAP1
Fusion gene ID: 51353
HgeneTgene
Gene symbol

MAP3K7

SMAP1

Gene ID

6885

60682

Gene namemitogen-activated protein kinase kinase kinase 7small ArfGAP 1
SynonymsCSCF|FMD2|MEKK7|TAK1|TGF1aSMAP-1
Cytomap

6q15

6q13

Type of geneprotein-codingprotein-coding
Descriptionmitogen-activated protein kinase kinase kinase 7TGF-beta activated kinase 1transforming growth factor-beta-activated kinase 1stromal membrane-associated protein 1stromal membrane-associated GTPase-activating protein 1
Modification date2020031320200313
UniProtAcc

O43318

.
Ensembl transtripts involved in fusion geneENST00000369325, ENST00000369327, 
ENST00000369329, ENST00000369332, 
ENST00000369320, ENST00000479630, 
ENST00000422334, ENST00000316999, 
ENST00000370452, ENST00000370455, 
Fusion gene scores* DoF score9 X 8 X 6=4329 X 7 X 6=378
# samples 109
** MAII scorelog2(10/432*10)=-2.11103131238874
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/378*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MAP3K7 [Title/Abstract] AND SMAP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMAP3K7(91296483)-SMAP1(71546644), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMAP3K7

GO:0000186

activation of MAPKK activity

8663074|9079627

HgeneMAP3K7

GO:0000187

activation of MAPK activity

9079627

HgeneMAP3K7

GO:0007252

I-kappaB phosphorylation

11460167

HgeneMAP3K7

GO:0007254

JNK cascade

9079627

HgeneMAP3K7

GO:0043507

positive regulation of JUN kinase activity

11460167

HgeneMAP3K7

GO:0043966

histone H3 acetylation

18838386

HgeneMAP3K7

GO:0051403

stress-activated MAPK cascade

9079627


check buttonFusion gene breakpoints across MAP3K7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SMAP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8080-01AMAP3K7chr6

91296483

-SMAP1chr6

71546644

+


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Fusion Gene ORF analysis for MAP3K7-SMAP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000369325ENST00000422334MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
5CDS-intronENST00000369327ENST00000422334MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
5CDS-intronENST00000369329ENST00000422334MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
5CDS-intronENST00000369332ENST00000422334MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369325ENST00000316999MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369325ENST00000370452MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369325ENST00000370455MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369327ENST00000316999MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369327ENST00000370452MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369327ENST00000370455MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369329ENST00000316999MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369329ENST00000370452MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369329ENST00000370455MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369332ENST00000316999MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369332ENST00000370452MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
In-frameENST00000369332ENST00000370455MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
intron-3CDSENST00000369320ENST00000316999MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
intron-3CDSENST00000369320ENST00000370452MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
intron-3CDSENST00000369320ENST00000370455MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
intron-3CDSENST00000479630ENST00000316999MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
intron-3CDSENST00000479630ENST00000370452MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
intron-3CDSENST00000479630ENST00000370455MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
intron-intronENST00000369320ENST00000422334MAP3K7chr6

91296483

-SMAP1chr6

71546644

+
intron-intronENST00000479630ENST00000422334MAP3K7chr6

91296483

-SMAP1chr6

71546644

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000369325MAP3K7chr691296483-ENST00000316999SMAP1chr671546644+17801200947315
ENST00000369325MAP3K7chr691296483-ENST00000370452SMAP1chr671546644+18681200935311
ENST00000369325MAP3K7chr691296483-ENST00000370455SMAP1chr671546644+26291200947315
ENST00000369327MAP3K7chr691296483-ENST00000316999SMAP1chr671546644+17861266953315
ENST00000369327MAP3K7chr691296483-ENST00000370452SMAP1chr671546644+18741266941311
ENST00000369327MAP3K7chr691296483-ENST00000370455SMAP1chr671546644+26351266953315
ENST00000369332MAP3K7chr691296483-ENST00000316999SMAP1chr671546644+19422821141109331
ENST00000369332MAP3K7chr691296483-ENST00000370452SMAP1chr671546644+20302821141097327
ENST00000369332MAP3K7chr691296483-ENST00000370455SMAP1chr671546644+27912821141109331
ENST00000369329MAP3K7chr691296483-ENST00000316999SMAP1chr671546644+19422821141109331
ENST00000369329MAP3K7chr691296483-ENST00000370452SMAP1chr671546644+20302821141097327
ENST00000369329MAP3K7chr691296483-ENST00000370455SMAP1chr671546644+27912821141109331

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000369325ENST00000316999MAP3K7chr691296483-SMAP1chr671546644+0.0006167110.9993832
ENST00000369325ENST00000370452MAP3K7chr691296483-SMAP1chr671546644+0.000443010.99955696
ENST00000369325ENST00000370455MAP3K7chr691296483-SMAP1chr671546644+0.0003214870.9996785
ENST00000369327ENST00000316999MAP3K7chr691296483-SMAP1chr671546644+0.000612640.9993874
ENST00000369327ENST00000370452MAP3K7chr691296483-SMAP1chr671546644+0.0004552970.9995447
ENST00000369327ENST00000370455MAP3K7chr691296483-SMAP1chr671546644+0.0003378050.99966216
ENST00000369332ENST00000316999MAP3K7chr691296483-SMAP1chr671546644+0.0006682020.9993318
ENST00000369332ENST00000370452MAP3K7chr691296483-SMAP1chr671546644+0.0004918590.99950814
ENST00000369332ENST00000370455MAP3K7chr691296483-SMAP1chr671546644+0.0003671720.99963284
ENST00000369329ENST00000316999MAP3K7chr691296483-SMAP1chr671546644+0.0006682020.9993318
ENST00000369329ENST00000370452MAP3K7chr691296483-SMAP1chr671546644+0.0004918590.99950814
ENST00000369329ENST00000370455MAP3K7chr691296483-SMAP1chr671546644+0.0003671720.99963284

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Fusion Genomic Features for MAP3K7-SMAP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MAP3K7-SMAP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:91296483/chr6:71546644)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MAP3K7

O43318

.
FUNCTION: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK). Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), while nuclear factor-kappa B is activated by IKK. MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1, but not that of NF-kappa-B. Promotes TRIM5 capsid-specific restriction activity. Phosphorylates RIPK1 at 'Ser-321' which positively regulates RIPK1 interaction with RIPK3 to promote necroptosis but negatively regulates RIPK1 kinase activity and its interaction with FADD to mediate apoptosis (By similarity). {ECO:0000250|UniProtKB:Q62073, ECO:0000269|PubMed:10094049, ECO:0000269|PubMed:11460167, ECO:0000269|PubMed:12589052, ECO:0000269|PubMed:16845370, ECO:0000269|PubMed:16893890, ECO:0000269|PubMed:21512573, ECO:0000269|PubMed:8663074, ECO:0000269|PubMed:9079627}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369325-1168_1440519.0Compositional biasNote=Poly-Ser
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369327-1158_1440492.0Compositional biasNote=Poly-Ser
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369329-1178_1440607.0Compositional biasNote=Poly-Ser
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369332-1168_1440580.0Compositional biasNote=Poly-Ser

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369325-11636_29140519.0DomainProtein kinase
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369327-11536_29140492.0DomainProtein kinase
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369329-11736_29140607.0DomainProtein kinase
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369332-11636_29140580.0DomainProtein kinase
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369325-11642_5040519.0Nucleotide bindingATP
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369327-11542_5040492.0Nucleotide bindingATP
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369329-11742_5040607.0Nucleotide bindingATP
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369332-11642_5040580.0Nucleotide bindingATP
TgeneSMAP1chr6:91296483chr6:71546644ENST0000031699941018_136165441.0DomainArf-GAP
TgeneSMAP1chr6:91296483chr6:71546644ENST0000037045241118_136165437.0DomainArf-GAP
TgeneSMAP1chr6:91296483chr6:71546644ENST0000037045551118_136192468.0DomainArf-GAP
TgeneSMAP1chr6:91296483chr6:71546644ENST0000031699941033_56165441.0Zinc fingerC4-type
TgeneSMAP1chr6:91296483chr6:71546644ENST0000037045241133_56165437.0Zinc fingerC4-type
TgeneSMAP1chr6:91296483chr6:71546644ENST0000037045551133_56192468.0Zinc fingerC4-type


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Fusion Gene Sequence for MAP3K7-SMAP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>51353_51353_1_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369325_SMAP1_chr6_71546644_ENST00000316999_length(transcript)=1780nt_BP=120nt
ATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAG
ATCGACTACAAGGAGATCGAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCG
GAGCCCACTGTGGATCTTTTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGAT
CTGGACATCTTTGGACCGATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCA
ACCCTGTCTACAGTAACATCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAA
GACTCCATCTTATCTCTGTATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACC
TCACAAGCACCAGCTGCATTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAG
AGTCCAAGCATGATGGTGGGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTT
GGCCCCCAAGGAGGAATGGTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCA
CAGATGAATCAGCAGATGGCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGG
TCTGGAAGCTCATCAGGTCAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATT
CCTTGCTGAAACGCATCTAGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATT
GACCGTGTTGGTCTGTACTGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTC
CCATGATTTCATGTACTGCATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCA
TATAAGGGAAGTAGTTATCATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGT
ATGATCAAATGTTTAATCATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTC
ACTTCACTGTGCTGTTGTTATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTT
AATGAATGCTTAAAGAATTCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTT
TCTGCACTATATGCAAACAGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAA

>51353_51353_1_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369325_SMAP1_chr6_71546644_ENST00000316999_length(amino acids)=315AA_BP=40
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDD
LDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFT
SQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLS

--------------------------------------------------------------
>51353_51353_2_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369325_SMAP1_chr6_71546644_ENST00000370452_length(transcript)=1868nt_BP=120nt
ATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAG
ATCGACTACAAGGAGATCGAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCG
GAGCCCACTGTGGATCTTTTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGAT
CTGGACATCTTTGGACCGATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCA
ACCCTGTCTACAGTAACATCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAA
GACTCCATCTTATCTCTGTATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACC
TCACAAGCACCAGCTGCATTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAG
AGTCCAAGCATGATGGTGGGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTT
GGCCCCCAAGGAGGAATGGTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCA
CAGATAATGCAGAAGGGTGATGCTGTTCTCCAGCACTCCATCAGTGCAATCTACTGGCCAATGACAAGGTGGTTAAAATGTCCTTTAGTA
GATGAATCAGCAGATGGCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTC
TGGAAGCTCATCAGGTCAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCC
TTGCTGAAACGCATCTAGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGA
CCGTGTTGGTCTGTACTGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCC
ATGATTTCATGTACTGCATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATA
TAAGGGAAGTAGTTATCATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTAT
GATCAAATGTTTAATCATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCAC
TTCACTGTGCTGTTGTTATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAA
TGAATGCTTAAAGAATTCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTC
TGCACTATATGCAAACAGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATT

>51353_51353_2_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369325_SMAP1_chr6_71546644_ENST00000370452_length(amino acids)=311AA_BP=40
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDD
LDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFT
SQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLS

--------------------------------------------------------------
>51353_51353_3_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369325_SMAP1_chr6_71546644_ENST00000370455_length(transcript)=2629nt_BP=120nt
ATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAG
ATCGACTACAAGGAGATCGAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCG
GAGCCCACTGTGGATCTTTTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGAT
CTGGACATCTTTGGACCGATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCA
ACCCTGTCTACAGTAACATCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAA
GACTCCATCTTATCTCTGTATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACC
TCACAAGCACCAGCTGCATTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAG
AGTCCAAGCATGATGGTGGGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTT
GGCCCCCAAGGAGGAATGGTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCA
CAGATGAATCAGCAGATGGCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGG
TCTGGAAGCTCATCAGGTCAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATT
CCTTGCTGAAACGCATCTAGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATT
GACCGTGTTGGTCTGTACTGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTC
CCATGATTTCATGTACTGCATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCA
TATAAGGGAAGTAGTTATCATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGT
ATGATCAAATGTTTAATCATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTC
ACTTCACTGTGCTGTTGTTATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTT
AATGAATGCTTAAAGAATTCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTT
TCTGCACTATATGCAAACAGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAA
TTGTGTTTACATTTTATGGTGCCTAGTATTGACAAAATGTTATTTCCCTACATTAAACATGACTCCATAGACCTTTTCATTTGTGGGTTT
TTATTTCCTATGATGTATACTGCCACTAACCTTCCAAAAATTACTTAGTATTGCAAAGTCAGGAATCATCAGGAACGTTTAGCTGACAAA
ATACTTGTCTGTTTTAAAAACCTGTTCAAGTCTACCAACCTGTTCAAGTCTACCAATTATAAGGGCAAATTGGAGAAAAAGAAAAAATAT
ATACTCAAGAGTGGTATCTTGCAGTATCGGCACTGTACAAAAAAATCTTCCAATTTAGTTGTTGTAGAGAAAACATGCAGAACAAATGAA
GACAAAACATACATTTTGTACCAACCATCCAATTAGCTTATGTTAACTGACAAGCTCCATTTAAACAGATGTCCATCAGATGACAAGAAA
GGCTGCTGTACTGAAGTAAAACAAACAATACCTGAATGCTCTGTAGCCTAAACTCCAAACATCCTCTTCCATATGGATCCACTGGCTGGA
CAAACTGCACCAGTTGCTGCTTCAATTTATACCTCAATTTTCACTGTGTCCAGGTGGTACTTTGGCTCGTTGGCTAGATTAACCTTCTCT
GTCCGAGTGTGCCACACGAGAACCTGAAGGGGAAGGAAATAGCTTGGGTAGCGCACTCTTCATGGTGACACTCGAGGTCGGGCAGCACAA
GTGTAATGAATACCTTAGTGCAGTTATTTGCTTTCGGTTCCAGTTCTTCGACTGTTGTTATCTGTTTGAGAAAGTCAGATTCTTGCATCC
CTGGCTGGGATCCACGACGCTTAAATACAGCTTTTGGATTGGACAAAATGACTTGAAGACTTACAGCAAATCCTTTGTGAAAAATAAAAA

>51353_51353_3_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369325_SMAP1_chr6_71546644_ENST00000370455_length(amino acids)=315AA_BP=40
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDD
LDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFT
SQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLS

--------------------------------------------------------------
>51353_51353_4_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369327_SMAP1_chr6_71546644_ENST00000316999_length(transcript)=1786nt_BP=126nt
GGGATCATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTT
GAAGAGATCGACTACAAGGAGATCGAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAA
GCTGCGGAGCCCACTGTGGATCTTTTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAAC
GATGATCTGGACATCTTTGGACCGATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCA
GCTGCAACCCTGTCTACAGTAACATCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTT
TCCAAAGACTCCATCTTATCTCTGTATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCA
TTTACCTCACAAGCACCAGCTGCATTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATG
GGACAGAGTCCAAGCATGATGGTGGGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAAC
GTTGTTGGCCCCCAAGGAGGAATGGTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGC
CTCTCACAGATGAATCAGCAGATGGCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCA
GGATGGTCTGGAAGCTCATCAGGTCAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCT
GACATTCCTTGCTGAAACGCATCTAGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGAT
CTGATTGACCGTGTTGGTCTGTACTGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCA
TATTTCCCATGATTTCATGTACTGCATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATG
TTTGCATATAAGGGAAGTAGTTATCATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGG
TACTGTATGATCAAATGTTTAATCATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCA
TCATTCACTTCACTGTGCTGTTGTTATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACT
TCGTTTAATGAATGCTTAAAGAATTCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGA
CCTTTTTCTGCACTATATGCAAACAGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGA

>51353_51353_4_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369327_SMAP1_chr6_71546644_ENST00000316999_length(amino acids)=315AA_BP=40
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDD
LDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFT
SQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLS

--------------------------------------------------------------
>51353_51353_5_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369327_SMAP1_chr6_71546644_ENST00000370452_length(transcript)=1874nt_BP=126nt
GGGATCATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTT
GAAGAGATCGACTACAAGGAGATCGAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAA
GCTGCGGAGCCCACTGTGGATCTTTTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAAC
GATGATCTGGACATCTTTGGACCGATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCA
GCTGCAACCCTGTCTACAGTAACATCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTT
TCCAAAGACTCCATCTTATCTCTGTATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCA
TTTACCTCACAAGCACCAGCTGCATTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATG
GGACAGAGTCCAAGCATGATGGTGGGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAAC
GTTGTTGGCCCCCAAGGAGGAATGGTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGC
CTCTCACAGATAATGCAGAAGGGTGATGCTGTTCTCCAGCACTCCATCAGTGCAATCTACTGGCCAATGACAAGGTGGTTAAAATGTCCT
TTAGTAGATGAATCAGCAGATGGCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGG
ATGGTCTGGAAGCTCATCAGGTCAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGA
CATTCCTTGCTGAAACGCATCTAGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCT
GATTGACCGTGTTGGTCTGTACTGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATA
TTTCCCATGATTTCATGTACTGCATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTT
TGCATATAAGGGAAGTAGTTATCATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTA
CTGTATGATCAAATGTTTAATCATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATC
ATTCACTTCACTGTGCTGTTGTTATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTC
GTTTAATGAATGCTTAAAGAATTCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACC
TTTTTCTGCACTATATGCAAACAGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACA

>51353_51353_5_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369327_SMAP1_chr6_71546644_ENST00000370452_length(amino acids)=311AA_BP=40
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDD
LDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFT
SQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLS

--------------------------------------------------------------
>51353_51353_6_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369327_SMAP1_chr6_71546644_ENST00000370455_length(transcript)=2635nt_BP=126nt
GGGATCATGTCTACAGCCTCTGCCGCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTT
GAAGAGATCGACTACAAGGAGATCGAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAA
GCTGCGGAGCCCACTGTGGATCTTTTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAAC
GATGATCTGGACATCTTTGGACCGATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCA
GCTGCAACCCTGTCTACAGTAACATCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTT
TCCAAAGACTCCATCTTATCTCTGTATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCA
TTTACCTCACAAGCACCAGCTGCATTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATG
GGACAGAGTCCAAGCATGATGGTGGGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAAC
GTTGTTGGCCCCCAAGGAGGAATGGTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGC
CTCTCACAGATGAATCAGCAGATGGCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCA
GGATGGTCTGGAAGCTCATCAGGTCAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCT
GACATTCCTTGCTGAAACGCATCTAGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGAT
CTGATTGACCGTGTTGGTCTGTACTGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCA
TATTTCCCATGATTTCATGTACTGCATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATG
TTTGCATATAAGGGAAGTAGTTATCATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGG
TACTGTATGATCAAATGTTTAATCATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCA
TCATTCACTTCACTGTGCTGTTGTTATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACT
TCGTTTAATGAATGCTTAAAGAATTCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGA
CCTTTTTCTGCACTATATGCAAACAGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGA
CAGTAATTGTGTTTACATTTTATGGTGCCTAGTATTGACAAAATGTTATTTCCCTACATTAAACATGACTCCATAGACCTTTTCATTTGT
GGGTTTTTATTTCCTATGATGTATACTGCCACTAACCTTCCAAAAATTACTTAGTATTGCAAAGTCAGGAATCATCAGGAACGTTTAGCT
GACAAAATACTTGTCTGTTTTAAAAACCTGTTCAAGTCTACCAACCTGTTCAAGTCTACCAATTATAAGGGCAAATTGGAGAAAAAGAAA
AAATATATACTCAAGAGTGGTATCTTGCAGTATCGGCACTGTACAAAAAAATCTTCCAATTTAGTTGTTGTAGAGAAAACATGCAGAACA
AATGAAGACAAAACATACATTTTGTACCAACCATCCAATTAGCTTATGTTAACTGACAAGCTCCATTTAAACAGATGTCCATCAGATGAC
AAGAAAGGCTGCTGTACTGAAGTAAAACAAACAATACCTGAATGCTCTGTAGCCTAAACTCCAAACATCCTCTTCCATATGGATCCACTG
GCTGGACAAACTGCACCAGTTGCTGCTTCAATTTATACCTCAATTTTCACTGTGTCCAGGTGGTACTTTGGCTCGTTGGCTAGATTAACC
TTCTCTGTCCGAGTGTGCCACACGAGAACCTGAAGGGGAAGGAAATAGCTTGGGTAGCGCACTCTTCATGGTGACACTCGAGGTCGGGCA
GCACAAGTGTAATGAATACCTTAGTGCAGTTATTTGCTTTCGGTTCCAGTTCTTCGACTGTTGTTATCTGTTTGAGAAAGTCAGATTCTT
GCATCCCTGGCTGGGATCCACGACGCTTAAATACAGCTTTTGGATTGGACAAAATGACTTGAAGACTTACAGCAAATCCTTTGTGAAAAA

>51353_51353_6_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369327_SMAP1_chr6_71546644_ENST00000370455_length(amino acids)=315AA_BP=40
MSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAVAPVTNGNTTVPPLNDD
LDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQQSTPGVFMGPTNIPFT
SQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWSLS

--------------------------------------------------------------
>51353_51353_7_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369329_SMAP1_chr6_71546644_ENST00000316999_length(transcript)=1942nt_BP=282nt
GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC
GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC
GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC
GAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAGCCCACTGTGGATCTT
TTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTGGACATCTTTGGACCG
ATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACCCTGTCTACAGTAACA
TCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGACTCCATCTTATCTCTG
TATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCACAAGCACCAGCTGCA
TTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGTCCAAGCATGATGGTG
GGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGCCCCCAAGGAGGAATG
GTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAGATGAATCAGCAGATG
GCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCTGGAAGCTCATCAGGT
CAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCTTGCTGAAACGCATCT
AGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGACCGTGTTGGTCTGTAC
TGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCATGATTTCATGTACTG
CATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATATAAGGGAAGTAGTTAT
CATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATGATCAAATGTTTAATC
ATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACTTCACTGTGCTGTTGT
TATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAATGAATGCTTAAAGAAT
TCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCTGCACTATATGCAAAC
AGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTGTGTTTACATTTTATG

>51353_51353_7_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369329_SMAP1_chr6_71546644_ENST00000316999_length(amino acids)=331AA_BP=56
MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAV
APVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQ
QSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQ

--------------------------------------------------------------
>51353_51353_8_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369329_SMAP1_chr6_71546644_ENST00000370452_length(transcript)=2030nt_BP=282nt
GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC
GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC
GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC
GAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAGCCCACTGTGGATCTT
TTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTGGACATCTTTGGACCG
ATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACCCTGTCTACAGTAACA
TCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGACTCCATCTTATCTCTG
TATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCACAAGCACCAGCTGCA
TTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGTCCAAGCATGATGGTG
GGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGCCCCCAAGGAGGAATG
GTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAGATAATGCAGAAGGGT
GATGCTGTTCTCCAGCACTCCATCAGTGCAATCTACTGGCCAATGACAAGGTGGTTAAAATGTCCTTTAGTAGATGAATCAGCAGATGGC
TGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCTGGAAGCTCATCAGGTCA
GACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCTTGCTGAAACGCATCTAG
TTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGACCGTGTTGGTCTGTACTG
ATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCATGATTTCATGTACTGCA
TTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATATAAGGGAAGTAGTTATCA
TGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATGATCAAATGTTTAATCAT
ATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACTTCACTGTGCTGTTGTTA
TGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAATGAATGCTTAAAGAATTC
AAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCTGCACTATATGCAAACAG
GGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTGTGTTTACATTTTATGGT

>51353_51353_8_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369329_SMAP1_chr6_71546644_ENST00000370452_length(amino acids)=327AA_BP=56
MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAV
APVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQ
QSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQ

--------------------------------------------------------------
>51353_51353_9_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369329_SMAP1_chr6_71546644_ENST00000370455_length(transcript)=2791nt_BP=282nt
GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC
GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC
GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC
GAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAGCCCACTGTGGATCTT
TTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTGGACATCTTTGGACCG
ATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACCCTGTCTACAGTAACA
TCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGACTCCATCTTATCTCTG
TATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCACAAGCACCAGCTGCA
TTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGTCCAAGCATGATGGTG
GGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGCCCCCAAGGAGGAATG
GTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAGATGAATCAGCAGATG
GCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCTGGAAGCTCATCAGGT
CAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCTTGCTGAAACGCATCT
AGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGACCGTGTTGGTCTGTAC
TGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCATGATTTCATGTACTG
CATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATATAAGGGAAGTAGTTAT
CATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATGATCAAATGTTTAATC
ATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACTTCACTGTGCTGTTGT
TATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAATGAATGCTTAAAGAAT
TCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCTGCACTATATGCAAAC
AGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTGTGTTTACATTTTATG
GTGCCTAGTATTGACAAAATGTTATTTCCCTACATTAAACATGACTCCATAGACCTTTTCATTTGTGGGTTTTTATTTCCTATGATGTAT
ACTGCCACTAACCTTCCAAAAATTACTTAGTATTGCAAAGTCAGGAATCATCAGGAACGTTTAGCTGACAAAATACTTGTCTGTTTTAAA
AACCTGTTCAAGTCTACCAACCTGTTCAAGTCTACCAATTATAAGGGCAAATTGGAGAAAAAGAAAAAATATATACTCAAGAGTGGTATC
TTGCAGTATCGGCACTGTACAAAAAAATCTTCCAATTTAGTTGTTGTAGAGAAAACATGCAGAACAAATGAAGACAAAACATACATTTTG
TACCAACCATCCAATTAGCTTATGTTAACTGACAAGCTCCATTTAAACAGATGTCCATCAGATGACAAGAAAGGCTGCTGTACTGAAGTA
AAACAAACAATACCTGAATGCTCTGTAGCCTAAACTCCAAACATCCTCTTCCATATGGATCCACTGGCTGGACAAACTGCACCAGTTGCT
GCTTCAATTTATACCTCAATTTTCACTGTGTCCAGGTGGTACTTTGGCTCGTTGGCTAGATTAACCTTCTCTGTCCGAGTGTGCCACACG
AGAACCTGAAGGGGAAGGAAATAGCTTGGGTAGCGCACTCTTCATGGTGACACTCGAGGTCGGGCAGCACAAGTGTAATGAATACCTTAG
TGCAGTTATTTGCTTTCGGTTCCAGTTCTTCGACTGTTGTTATCTGTTTGAGAAAGTCAGATTCTTGCATCCCTGGCTGGGATCCACGAC
GCTTAAATACAGCTTTTGGATTGGACAAAATGACTTGAAGACTTACAGCAAATCCTTTGTGAAAAATAAAAAAAAAAAAGAGACTTTAAA

>51353_51353_9_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369329_SMAP1_chr6_71546644_ENST00000370455_length(amino acids)=331AA_BP=56
MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAV
APVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQ
QSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQ

--------------------------------------------------------------
>51353_51353_10_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369332_SMAP1_chr6_71546644_ENST00000316999_length(transcript)=1942nt_BP=282nt
GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC
GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC
GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC
GAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAGCCCACTGTGGATCTT
TTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTGGACATCTTTGGACCG
ATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACCCTGTCTACAGTAACA
TCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGACTCCATCTTATCTCTG
TATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCACAAGCACCAGCTGCA
TTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGTCCAAGCATGATGGTG
GGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGCCCCCAAGGAGGAATG
GTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAGATGAATCAGCAGATG
GCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCTGGAAGCTCATCAGGT
CAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCTTGCTGAAACGCATCT
AGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGACCGTGTTGGTCTGTAC
TGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCATGATTTCATGTACTG
CATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATATAAGGGAAGTAGTTAT
CATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATGATCAAATGTTTAATC
ATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACTTCACTGTGCTGTTGT
TATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAATGAATGCTTAAAGAAT
TCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCTGCACTATATGCAAAC
AGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTGTGTTTACATTTTATG

>51353_51353_10_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369332_SMAP1_chr6_71546644_ENST00000316999_length(amino acids)=331AA_BP=56
MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAV
APVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQ
QSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQ

--------------------------------------------------------------
>51353_51353_11_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369332_SMAP1_chr6_71546644_ENST00000370452_length(transcript)=2030nt_BP=282nt
GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC
GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC
GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC
GAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAGCCCACTGTGGATCTT
TTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTGGACATCTTTGGACCG
ATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACCCTGTCTACAGTAACA
TCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGACTCCATCTTATCTCTG
TATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCACAAGCACCAGCTGCA
TTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGTCCAAGCATGATGGTG
GGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGCCCCCAAGGAGGAATG
GTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAGATAATGCAGAAGGGT
GATGCTGTTCTCCAGCACTCCATCAGTGCAATCTACTGGCCAATGACAAGGTGGTTAAAATGTCCTTTAGTAGATGAATCAGCAGATGGC
TGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCTGGAAGCTCATCAGGTCA
GACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCTTGCTGAAACGCATCTAG
TTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGACCGTGTTGGTCTGTACTG
ATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCATGATTTCATGTACTGCA
TTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATATAAGGGAAGTAGTTATCA
TGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATGATCAAATGTTTAATCAT
ATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACTTCACTGTGCTGTTGTTA
TGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAATGAATGCTTAAAGAATTC
AAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCTGCACTATATGCAAACAG
GGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTGTGTTTACATTTTATGGT

>51353_51353_11_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369332_SMAP1_chr6_71546644_ENST00000370452_length(amino acids)=327AA_BP=56
MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAV
APVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQ
QSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQ

--------------------------------------------------------------
>51353_51353_12_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369332_SMAP1_chr6_71546644_ENST00000370455_length(transcript)=2791nt_BP=282nt
GGACACGGCTGTGGCCGCTGCCTCTACCCCCGCCACGGATCGCCGGGTAGTAGGACTGCGCGGCTCCAGGCTGAGGGTCGGTCCGGAGGC
GGGTGGGCGCGGGTCTCACCCGGATTGTCCGGGTGGCACCGTTCCCGGCCCCACCGGGCGCCGCGAGGGATCATGTCTACAGCCTCTGCC
GCCTCCTCCTCCTCCTCGTCTTCGGCCGGTGAGATGATCGAAGCCCCTTCCCAGGTCCTCAACTTTGAAGAGATCGACTACAAGGAGATC
GAGGTGGAAGAGCTGCAGAAGAAAGATCAGCAACTGGAGCCTAAAAAAAGTACCAGCCCTAAAAAAGCTGCGGAGCCCACTGTGGATCTT
TTAGGACTTGATGGCCCTGCTGTGGCACCAGTGACCAACGGGAACACAACGGTGCCACCCCTGAACGATGATCTGGACATCTTTGGACCG
ATGATTTCTAATCCCTTACCTGCAACTGTCATGCCCCCAGCTCAGGGGACACCCTCTGCACCAGCAGCTGCAACCCTGTCTACAGTAACA
TCTGGGGATCTAGATTTATTCACTGAGCAAACTACAAAATCAGAAGAAGTGGCAAAGAAACAACTTTCCAAAGACTCCATCTTATCTCTG
TATGGCACAGGAACCATTCAACAGCAAAGTACTCCTGGTGTATTTATGGGACCCACAAATATACCATTTACCTCACAAGCACCAGCTGCA
TTTCAGGGCTTTCCATCGATGGGCGTGCCTGTGCCTGCAGCTCCTGGCCTTATAGGAAATGTGATGGGACAGAGTCCAAGCATGATGGTG
GGCATGCCCATGCCCAATGGGTTTATGGGAAATGCACAAACTGGTGTGATGCCACTTCCTCAGAACGTTGTTGGCCCCCAAGGAGGAATG
GTGGGACAAATGGGTGCACCCCAGAGTAAGTTTGGCCTGCCGCAAGCTCAGCAGCCCCAGTGGAGCCTCTCACAGATGAATCAGCAGATG
GCTGGCATGAGTATCAGTAGTGCAACCCCTACTGCAGGTTTTGGCCAGCCCTCCAGCACAACAGCAGGATGGTCTGGAAGCTCATCAGGT
CAGACTCTCAGCACACAACTGTGGAAATGAAAACTGCAATACAAGTTTCATCCAGAACTACCACCTGACATTCCTTGCTGAAACGCATCT
AGTTCCCCTGTTTATTCATATGCATATTTTTTTTCTTTTTACCCATTTGTTCATATTAAGAATGATCTGATTGACCGTGTTGGTCTGTAC
TGATTCAATTTGATGTGGTGAAAAGCAGGTTGATAAATCATTTTATGTCAAGGGCAGCTTTGCTCATATTTCCCATGATTTCATGTACTG
CATTATTTGAGAAGCTGCTCAACTTGCAAAATCAGTTTTCCTCTCAATAAAATTATAGCTCTAATGTTTGCATATAAGGGAAGTAGTTAT
CATGTTAGTAATACCTCTAATAGTATAAACCCCACCCCAAAATTAGCCAGTAATCCTGTAGGAAGGTACTGTATGATCAAATGTTTAATC
ATATAAATAGAATGTAAATGTCTCACTGAGCACTGTTTTCTAGTGTATCAAAATGCTCTTATTTCATCATTCACTTCACTGTGCTGTTGT
TATGATGTGCTTAACAGGGAACGTGATTAGTGAAAGGAAGATAAACGTGGATGTTACTCCAAAACTTCGTTTAATGAATGCTTAAAGAAT
TCAAATTTTATCTGCCTCTCTTGTAATTTGGATCTCTTCTTAATGTACATAGTGCTAACATGAAGACCTTTTTCTGCACTATATGCAAAC
AGGGTAACTAACTAAAACAAAGCCACTTTCAATCTTCAATCCTTGAAGGTATATCTAGGTTTATGACAGTAATTGTGTTTACATTTTATG
GTGCCTAGTATTGACAAAATGTTATTTCCCTACATTAAACATGACTCCATAGACCTTTTCATTTGTGGGTTTTTATTTCCTATGATGTAT
ACTGCCACTAACCTTCCAAAAATTACTTAGTATTGCAAAGTCAGGAATCATCAGGAACGTTTAGCTGACAAAATACTTGTCTGTTTTAAA
AACCTGTTCAAGTCTACCAACCTGTTCAAGTCTACCAATTATAAGGGCAAATTGGAGAAAAAGAAAAAATATATACTCAAGAGTGGTATC
TTGCAGTATCGGCACTGTACAAAAAAATCTTCCAATTTAGTTGTTGTAGAGAAAACATGCAGAACAAATGAAGACAAAACATACATTTTG
TACCAACCATCCAATTAGCTTATGTTAACTGACAAGCTCCATTTAAACAGATGTCCATCAGATGACAAGAAAGGCTGCTGTACTGAAGTA
AAACAAACAATACCTGAATGCTCTGTAGCCTAAACTCCAAACATCCTCTTCCATATGGATCCACTGGCTGGACAAACTGCACCAGTTGCT
GCTTCAATTTATACCTCAATTTTCACTGTGTCCAGGTGGTACTTTGGCTCGTTGGCTAGATTAACCTTCTCTGTCCGAGTGTGCCACACG
AGAACCTGAAGGGGAAGGAAATAGCTTGGGTAGCGCACTCTTCATGGTGACACTCGAGGTCGGGCAGCACAAGTGTAATGAATACCTTAG
TGCAGTTATTTGCTTTCGGTTCCAGTTCTTCGACTGTTGTTATCTGTTTGAGAAAGTCAGATTCTTGCATCCCTGGCTGGGATCCACGAC
GCTTAAATACAGCTTTTGGATTGGACAAAATGACTTGAAGACTTACAGCAAATCCTTTGTGAAAAATAAAAAAAAAAAAGAGACTTTAAA

>51353_51353_12_MAP3K7-SMAP1_MAP3K7_chr6_91296483_ENST00000369332_SMAP1_chr6_71546644_ENST00000370455_length(amino acids)=331AA_BP=56
MSGWHRSRPHRAPRGIMSTASAASSSSSSSAGEMIEAPSQVLNFEEIDYKEIEVEELQKKDQQLEPKKSTSPKKAAEPTVDLLGLDGPAV
APVTNGNTTVPPLNDDLDIFGPMISNPLPATVMPPAQGTPSAPAAATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGTIQQ
QSTPGVFMGPTNIPFTSQAPAAFQGFPSMGVPVPAAPGLIGNVMGQSPSMMVGMPMPNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MAP3K7-SMAP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369325-1161_30040.0519.0MAPK8IP1
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369327-1151_30040.0492.0MAPK8IP1
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369329-1171_30040.0607.0MAPK8IP1
HgeneMAP3K7chr6:91296483chr6:71546644ENST00000369332-1161_30040.0580.0MAPK8IP1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MAP3K7-SMAP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MAP3K7-SMAP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource