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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MAST2-COQ6 (FusionGDB2 ID:51821)

Fusion Gene Summary for MAST2-COQ6

check button Fusion gene summary
Fusion gene informationFusion gene name: MAST2-COQ6
Fusion gene ID: 51821
HgeneTgene
Gene symbol

MAST2

COQ6

Gene ID

23139

51004

Gene namemicrotubule associated serine/threonine kinase 2coenzyme Q6, monooxygenase
SynonymsMAST205|MTSSKCGI-10|CGI10|COQ10D6
Cytomap

1p34.1

14q24.3

Type of geneprotein-codingprotein-coding
Descriptionmicrotubule-associated serine/threonine-protein kinase 2microtubule associated testis specific serine/threonine protein kinaseubiquinone biosynthesis monooxygenase COQ6, mitochondrialcoenzyme Q10 monooxygenase 6coenzyme Q6 homolog, monooxygenase
Modification date2020031320200313
UniProtAcc

Q6P0Q8

Q9Y2Z9

Ensembl transtripts involved in fusion geneENST00000361297, ENST00000372009, 
ENST00000477968, 		ENST00000554920, 
ENST00000555552, ENST00000238709, 
ENST00000334571, ENST00000394026, 
Fusion gene scores* DoF score25 X 15 X 13=48753 X 4 X 3=36
# samples 284
** MAII scorelog2(28/4875*10)=-4.12190348657937
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: MAST2 [Title/Abstract] AND COQ6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMAST2(46474043)-COQ6(74425674), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MAST2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across COQ6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-FC-A5OB-01AMAST2chr1

46474043

-COQ6chr14

74425674

+
ChimerDB4PRADTCGA-FC-A5OB-01AMAST2chr1

46474043

+COQ6chr14

74425674

+
ChimerDB4PRADTCGA-FC-A5OBMAST2chr1

46474043

+COQ6chr14

74425674

+


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Fusion Gene ORF analysis for MAST2-COQ6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000361297ENST00000554920MAST2chr1

46474043

+COQ6chr14

74425674

+
5CDS-intronENST00000361297ENST00000555552MAST2chr1

46474043

+COQ6chr14

74425674

+
5CDS-intronENST00000372009ENST00000554920MAST2chr1

46474043

+COQ6chr14

74425674

+
5CDS-intronENST00000372009ENST00000555552MAST2chr1

46474043

+COQ6chr14

74425674

+
In-frameENST00000361297ENST00000238709MAST2chr1

46474043

+COQ6chr14

74425674

+
In-frameENST00000361297ENST00000334571MAST2chr1

46474043

+COQ6chr14

74425674

+
In-frameENST00000361297ENST00000394026MAST2chr1

46474043

+COQ6chr14

74425674

+
In-frameENST00000372009ENST00000238709MAST2chr1

46474043

+COQ6chr14

74425674

+
In-frameENST00000372009ENST00000334571MAST2chr1

46474043

+COQ6chr14

74425674

+
In-frameENST00000372009ENST00000394026MAST2chr1

46474043

+COQ6chr14

74425674

+
intron-3CDSENST00000477968ENST00000238709MAST2chr1

46474043

+COQ6chr14

74425674

+
intron-3CDSENST00000477968ENST00000334571MAST2chr1

46474043

+COQ6chr14

74425674

+
intron-3CDSENST00000477968ENST00000394026MAST2chr1

46474043

+COQ6chr14

74425674

+
intron-intronENST00000477968ENST00000554920MAST2chr1

46474043

+COQ6chr14

74425674

+
intron-intronENST00000477968ENST00000555552MAST2chr1

46474043

+COQ6chr14

74425674

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000372009MAST2chr146474043+ENST00000394026COQ6chr1474425674+216512612832055590
ENST00000372009MAST2chr146474043+ENST00000238709COQ6chr1474425674+216512612832055590
ENST00000372009MAST2chr146474043+ENST00000334571COQ6chr1474425674+272712612832055590
ENST00000361297MAST2chr146474043+ENST00000394026COQ6chr1474425674+216512612832055590
ENST00000361297MAST2chr146474043+ENST00000238709COQ6chr1474425674+216512612832055590
ENST00000361297MAST2chr146474043+ENST00000334571COQ6chr1474425674+272712612832055590

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000372009ENST00000394026MAST2chr146474043+COQ6chr1474425674+0.0551356450.9448644
ENST00000372009ENST00000238709MAST2chr146474043+COQ6chr1474425674+0.0551356450.9448644
ENST00000372009ENST00000334571MAST2chr146474043+COQ6chr1474425674+0.0329389050.9670611
ENST00000361297ENST00000394026MAST2chr146474043+COQ6chr1474425674+0.0551356450.9448644
ENST00000361297ENST00000238709MAST2chr146474043+COQ6chr1474425674+0.0551356450.9448644
ENST00000361297ENST00000334571MAST2chr146474043+COQ6chr1474425674+0.0329389050.9670611

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Fusion Genomic Features for MAST2-COQ6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MAST2-COQ6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:46474043/chr14:74425674)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MAST2

Q6P0Q8

COQ6

Q9Y2Z9

FUNCTION: Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity). {ECO:0000250}.FUNCTION: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-hexaprenyl-4-hydroxybenzoic acid (HHB) to 3-hexaprenyl-4,5-dihydroxybenzoic acid (DHHB). The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6 (By similarity). Is able to perform the deamination reaction at C4 of 3-hexaprenyl-4-amino-5-hydroxybenzoic acid (HHAB) to produce DHHB when expressed in yeast cells lacking COQ9, even if utilization of para-aminobenzoic acid (pABA) involving C4-deamination seems not to occur in bacteria, plants and mammals, where only C5 hydroxylation of HHB has been shown (PubMed:26260787). {ECO:0000255|HAMAP-Rule:MF_03193, ECO:0000269|PubMed:26260787}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMAST2chr1:46474043chr14:74425674ENST00000361297+9291104_11923261799.0DomainPDZ
HgeneMAST2chr1:46474043chr14:74425674ENST00000361297+929512_7853261799.0DomainProtein kinase
HgeneMAST2chr1:46474043chr14:74425674ENST00000361297+929786_8543261799.0DomainAGC-kinase C-terminal
HgeneMAST2chr1:46474043chr14:74425674ENST00000361297+929518_5263261799.0Nucleotide bindingATP


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Fusion Gene Sequence for MAST2-COQ6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>51821_51821_1_MAST2-COQ6_MAST2_chr1_46474043_ENST00000361297_COQ6_chr14_74425674_ENST00000238709_length(transcript)=2165nt_BP=1261nt
TAGGCAGGCGGCTGAGCCGGCGGCGGGTGGCCTGCCCAACGTGTGCTGGGTGGGAGAAGGCGAGGCGTCAGCGATGCTGTCTCTTCCGTG
AGGAGCGCAGAGGAGGTCGCGGCGCCGGAGGCCCCAGAAGGCTCGAAGGCGCCGCGGGCTGGGGTCGGTGGCTTAGGGAGCCCGTCCGGC
CATGGTGGCCGCGGGTGGTGGTTGGCGCGGCTGCGCTGCGGCCCGGGGCAGTGCGGAGCCGGGACAGTCGCGGCGCTGACGCCCGCGGGC
CCCAGCTGCAGATATGAAGCGGAGCCGCTGCCGCGACCGACCGCAGCCGCCGCCGCCCGACCGCCGGGAGGATGGAGTTCAGCGGGCAGC
GGAGCTGTCTCAGTCTTTGCCGCCGCGCCGGCGAGCGCCGCCCGGGAGGCAGCGGCTGGAGGAGCGGACGGGCCCCGCGGGGCCCGAGGG
CAAGGAGCAGGATGTAGTAACTGGAGTTAGTCCCCTGCTCTTCAGGAAACTCAGTAATCCTGACATATTTTCATCCACTGGAAAAGTTAA
ACTTCAGCGACAACTGAGTCAGGATGATTGTAAGTTATGGAGAGGAAACCTGGCCAGCTCTCTATCGGGTAAGCAGCTGCTCCCTTTGTC
CAGCAGTGTACATAGCAGTGTGGGACAGGTGACTTGGCAGTCGTCAGGAGAAGCATCAAACCTGGTTCGAATGAGAAACCAGTCCCTTGG
ACAGTCTGCACCTTCTCTTACTGCTGGCCTGAAGGAGTTGAGCCTTCCAAGAAGAGGCAGCTTTTGTCGGACAAGTAACCGCAAGAGCTT
GATTGTGACCTCTAGCACATCACCTACACTACCACGGCCACACTCACCACTCCATGGCCACACAGGTAACAGTCCTTTGGACAGCCCCCG
GAATTTCTCTCCAAATGCACCTGCTCACTTTTCTTTTGTTCCTGCCCGTAGGACTGATGGGCGGCGCTGGTCTTTGGCCTCTTTGCCCTC
TTCAGGATATGGAACTAACACTCCTAGCTCCACTGTCTCATCATCATGCTCCTCACAGGAAAAGCTGCATCAGTTGCCTTTCCAGCCTAC
AGCTGATGAGCTGCACTTTTTGACGAAGCATTTCAGCACAGAGAGCGTACCAGATGAGGAAGGACGGCAGTCCCCAGCCATGCGGCCTCG
CTCCCGGAGCCTCAGTCCCGGACGATCCCCAGTATCCTTTGACAGTGAAATAATAATGATGAATCATGTTTACAAAGAAAGATTCCCAAA
GATAGGTGCAGATGGTCACAACTCCGGAGTACGGCAGGCTGTTGGAATCCAGAATGTGAGCTGGAACTATGACCAGTCTGCTGTTGTGGC
TACTCTGCATTTATCAGAGGCCACAGAAAACAACGTAGCCTGGCAGAGATTTCTTCCCTCTGGGCCTATTGCTCTGCTCCCGCTCTCAGA
CACCTTGAGTTCCTTGGTTTGGTCCACGTCCCATGAACATGCAGCAGAGCTAGTTAGCATGGATGAGGAAAAATTTGTGGATGCCGTTAA
CTCTGCCTTTTGGAGTGATGCTGACCACACGGACTTCATCGACACAGCTGGTGCCATGCTGCAGTATGCTGTCAGCCTTCTGAAGCCCAC
TAAGGTCTCGGCTCGCCAGCTGCCCCCAAGCGTAGCCAGGGTGGATGCCAAAAGCCGAGTTCTGTTTCCTCTTGGGTTGGGACATGCTGC
TGAGTACGTCAGGCCTCGGGTGGCGCTCATTGGGGATGCAGCCCACAGAGTCCATCCGCTTGCAGGACAGGGTGTCAACATGGGCTTTGG
GGATATCTCCAGCTTGGCCCATCACCTCAGTACGGCAGCCTTCAATGGGAAGGACTTAGGTTCCGTGAGCCACCTCACAGGTTATGAAAC
AGAAAGACAGCGTCACAACACTGCTCTTCTGGCTGCTACAGACTTACTAAAAAGGCTCTATTCTACCAGTGCCTCCCCGCTTGTGTTGCT
CAGGACGTGGGGCTTGCAGGCCACAAATGCAGTGTCTCCACTCAAAGAACAGATTATGGCCTTTGCAAGCAAATGAGTACTCCTCTCCTA
AAGAAAGATTACGTTGATGAAAAAGAACATCCTGCCCAGGACCCATCATACATATTTTCAAGATCTTATTTAATTTAATAAACTTACTTT

>51821_51821_1_MAST2-COQ6_MAST2_chr1_46474043_ENST00000361297_COQ6_chr14_74425674_ENST00000238709_length(amino acids)=590AA_BP=326
MKRSRCRDRPQPPPPDRREDGVQRAAELSQSLPPRRRAPPGRQRLEERTGPAGPEGKEQDVVTGVSPLLFRKLSNPDIFSSTGKVKLQRQ
LSQDDCKLWRGNLASSLSGKQLLPLSSSVHSSVGQVTWQSSGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKSLIVTS
STSPTLPRPHSPLHGHTGNSPLDSPRNFSPNAPAHFSFVPARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADEL
HFLTKHFSTESVPDEEGRQSPAMRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHL
SEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSDADHTDFIDTAGAMLQYAVSLLKPTKVSA
RQLPPSVARVDAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQR

--------------------------------------------------------------
>51821_51821_2_MAST2-COQ6_MAST2_chr1_46474043_ENST00000361297_COQ6_chr14_74425674_ENST00000334571_length(transcript)=2727nt_BP=1261nt
TAGGCAGGCGGCTGAGCCGGCGGCGGGTGGCCTGCCCAACGTGTGCTGGGTGGGAGAAGGCGAGGCGTCAGCGATGCTGTCTCTTCCGTG
AGGAGCGCAGAGGAGGTCGCGGCGCCGGAGGCCCCAGAAGGCTCGAAGGCGCCGCGGGCTGGGGTCGGTGGCTTAGGGAGCCCGTCCGGC
CATGGTGGCCGCGGGTGGTGGTTGGCGCGGCTGCGCTGCGGCCCGGGGCAGTGCGGAGCCGGGACAGTCGCGGCGCTGACGCCCGCGGGC
CCCAGCTGCAGATATGAAGCGGAGCCGCTGCCGCGACCGACCGCAGCCGCCGCCGCCCGACCGCCGGGAGGATGGAGTTCAGCGGGCAGC
GGAGCTGTCTCAGTCTTTGCCGCCGCGCCGGCGAGCGCCGCCCGGGAGGCAGCGGCTGGAGGAGCGGACGGGCCCCGCGGGGCCCGAGGG
CAAGGAGCAGGATGTAGTAACTGGAGTTAGTCCCCTGCTCTTCAGGAAACTCAGTAATCCTGACATATTTTCATCCACTGGAAAAGTTAA
ACTTCAGCGACAACTGAGTCAGGATGATTGTAAGTTATGGAGAGGAAACCTGGCCAGCTCTCTATCGGGTAAGCAGCTGCTCCCTTTGTC
CAGCAGTGTACATAGCAGTGTGGGACAGGTGACTTGGCAGTCGTCAGGAGAAGCATCAAACCTGGTTCGAATGAGAAACCAGTCCCTTGG
ACAGTCTGCACCTTCTCTTACTGCTGGCCTGAAGGAGTTGAGCCTTCCAAGAAGAGGCAGCTTTTGTCGGACAAGTAACCGCAAGAGCTT
GATTGTGACCTCTAGCACATCACCTACACTACCACGGCCACACTCACCACTCCATGGCCACACAGGTAACAGTCCTTTGGACAGCCCCCG
GAATTTCTCTCCAAATGCACCTGCTCACTTTTCTTTTGTTCCTGCCCGTAGGACTGATGGGCGGCGCTGGTCTTTGGCCTCTTTGCCCTC
TTCAGGATATGGAACTAACACTCCTAGCTCCACTGTCTCATCATCATGCTCCTCACAGGAAAAGCTGCATCAGTTGCCTTTCCAGCCTAC
AGCTGATGAGCTGCACTTTTTGACGAAGCATTTCAGCACAGAGAGCGTACCAGATGAGGAAGGACGGCAGTCCCCAGCCATGCGGCCTCG
CTCCCGGAGCCTCAGTCCCGGACGATCCCCAGTATCCTTTGACAGTGAAATAATAATGATGAATCATGTTTACAAAGAAAGATTCCCAAA
GATAGGTGCAGATGGTCACAACTCCGGAGTACGGCAGGCTGTTGGAATCCAGAATGTGAGCTGGAACTATGACCAGTCTGCTGTTGTGGC
TACTCTGCATTTATCAGAGGCCACAGAAAACAACGTAGCCTGGCAGAGATTTCTTCCCTCTGGGCCTATTGCTCTGCTCCCGCTCTCAGA
CACCTTGAGTTCCTTGGTTTGGTCCACGTCCCATGAACATGCAGCAGAGCTAGTTAGCATGGATGAGGAAAAATTTGTGGATGCCGTTAA
CTCTGCCTTTTGGAGTGATGCTGACCACACGGACTTCATCGACACAGCTGGTGCCATGCTGCAGTATGCTGTCAGCCTTCTGAAGCCCAC
TAAGGTCTCGGCTCGCCAGCTGCCCCCAAGCGTAGCCAGGGTGGATGCCAAAAGCCGAGTTCTGTTTCCTCTTGGGTTGGGACATGCTGC
TGAGTACGTCAGGCCTCGGGTGGCGCTCATTGGGGATGCAGCCCACAGAGTCCATCCGCTTGCAGGACAGGGTGTCAACATGGGCTTTGG
GGATATCTCCAGCTTGGCCCATCACCTCAGTACGGCAGCCTTCAATGGGAAGGACTTAGGTTCCGTGAGCCACCTCACAGGTTATGAAAC
AGAAAGACAGCGTCACAACACTGCTCTTCTGGCTGCTACAGACTTACTAAAAAGGCTCTATTCTACCAGTGCCTCCCCGCTTGTGTTGCT
CAGGACGTGGGGCTTGCAGGCCACAAATGCAGTGTCTCCACTCAAAGAACAGATTATGGCCTTTGCAAGCAAATGAGTACTCCTCTCCTA
AAGAAAGATTACGTTGATGAAAAAGAACATCCTGCCCAGGACCCATCATACATATTTTCAAGATCTTATTTAATTTAATAAACTTACTTT
ACATTAAAATTCTCTTTTTCTTCTTTGCTTAATGGGCCTGTGGCACCCAAATAATGAATGATAATTTGCTGTGAGGAGCGTATATTAGCC
AGACCAAAGGAAAAAACTTCGAAGGAAGACTTACAATTTGGTTGAAAAGAGCTTTTTATTACTAAAAAACCCACAAGGTGCTGTCTCACT
CATTTCCAGTTAATCATTTCTAAAGAGAAAATTTACATTTTGTTTTTGTTTTAATGTTGGTCATAAATTTATACAGTTGTTTTTTGATAG
AGGTAAGAATTAGACTCGATGCATTTTTGTTAGAATTGCTGTTTAAATGTTAACATCAGAATGCAAATTAAATATAAATTGCTTTAACCT
TTGTTACAGGTATACTGGACTTTCTGAAAGGAAAACCAGGTCTCATTAATGCTAGTTATTACTTTATCACAGCACCAGATTTCCATTTTA
TTTATGGTTCCTCTCTGGGACACCACTGTCGGTTTAATAAAACAATAAATAATTCATTGCACAGATCCGAAGACCTCAGGAACCAGATCA

>51821_51821_2_MAST2-COQ6_MAST2_chr1_46474043_ENST00000361297_COQ6_chr14_74425674_ENST00000334571_length(amino acids)=590AA_BP=326
MKRSRCRDRPQPPPPDRREDGVQRAAELSQSLPPRRRAPPGRQRLEERTGPAGPEGKEQDVVTGVSPLLFRKLSNPDIFSSTGKVKLQRQ
LSQDDCKLWRGNLASSLSGKQLLPLSSSVHSSVGQVTWQSSGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKSLIVTS
STSPTLPRPHSPLHGHTGNSPLDSPRNFSPNAPAHFSFVPARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADEL
HFLTKHFSTESVPDEEGRQSPAMRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHL
SEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSDADHTDFIDTAGAMLQYAVSLLKPTKVSA
RQLPPSVARVDAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQR

--------------------------------------------------------------
>51821_51821_3_MAST2-COQ6_MAST2_chr1_46474043_ENST00000361297_COQ6_chr14_74425674_ENST00000394026_length(transcript)=2165nt_BP=1261nt
TAGGCAGGCGGCTGAGCCGGCGGCGGGTGGCCTGCCCAACGTGTGCTGGGTGGGAGAAGGCGAGGCGTCAGCGATGCTGTCTCTTCCGTG
AGGAGCGCAGAGGAGGTCGCGGCGCCGGAGGCCCCAGAAGGCTCGAAGGCGCCGCGGGCTGGGGTCGGTGGCTTAGGGAGCCCGTCCGGC
CATGGTGGCCGCGGGTGGTGGTTGGCGCGGCTGCGCTGCGGCCCGGGGCAGTGCGGAGCCGGGACAGTCGCGGCGCTGACGCCCGCGGGC
CCCAGCTGCAGATATGAAGCGGAGCCGCTGCCGCGACCGACCGCAGCCGCCGCCGCCCGACCGCCGGGAGGATGGAGTTCAGCGGGCAGC
GGAGCTGTCTCAGTCTTTGCCGCCGCGCCGGCGAGCGCCGCCCGGGAGGCAGCGGCTGGAGGAGCGGACGGGCCCCGCGGGGCCCGAGGG
CAAGGAGCAGGATGTAGTAACTGGAGTTAGTCCCCTGCTCTTCAGGAAACTCAGTAATCCTGACATATTTTCATCCACTGGAAAAGTTAA
ACTTCAGCGACAACTGAGTCAGGATGATTGTAAGTTATGGAGAGGAAACCTGGCCAGCTCTCTATCGGGTAAGCAGCTGCTCCCTTTGTC
CAGCAGTGTACATAGCAGTGTGGGACAGGTGACTTGGCAGTCGTCAGGAGAAGCATCAAACCTGGTTCGAATGAGAAACCAGTCCCTTGG
ACAGTCTGCACCTTCTCTTACTGCTGGCCTGAAGGAGTTGAGCCTTCCAAGAAGAGGCAGCTTTTGTCGGACAAGTAACCGCAAGAGCTT
GATTGTGACCTCTAGCACATCACCTACACTACCACGGCCACACTCACCACTCCATGGCCACACAGGTAACAGTCCTTTGGACAGCCCCCG
GAATTTCTCTCCAAATGCACCTGCTCACTTTTCTTTTGTTCCTGCCCGTAGGACTGATGGGCGGCGCTGGTCTTTGGCCTCTTTGCCCTC
TTCAGGATATGGAACTAACACTCCTAGCTCCACTGTCTCATCATCATGCTCCTCACAGGAAAAGCTGCATCAGTTGCCTTTCCAGCCTAC
AGCTGATGAGCTGCACTTTTTGACGAAGCATTTCAGCACAGAGAGCGTACCAGATGAGGAAGGACGGCAGTCCCCAGCCATGCGGCCTCG
CTCCCGGAGCCTCAGTCCCGGACGATCCCCAGTATCCTTTGACAGTGAAATAATAATGATGAATCATGTTTACAAAGAAAGATTCCCAAA
GATAGGTGCAGATGGTCACAACTCCGGAGTACGGCAGGCTGTTGGAATCCAGAATGTGAGCTGGAACTATGACCAGTCTGCTGTTGTGGC
TACTCTGCATTTATCAGAGGCCACAGAAAACAACGTAGCCTGGCAGAGATTTCTTCCCTCTGGGCCTATTGCTCTGCTCCCGCTCTCAGA
CACCTTGAGTTCCTTGGTTTGGTCCACGTCCCATGAACATGCAGCAGAGCTAGTTAGCATGGATGAGGAAAAATTTGTGGATGCCGTTAA
CTCTGCCTTTTGGAGTGATGCTGACCACACGGACTTCATCGACACAGCTGGTGCCATGCTGCAGTATGCTGTCAGCCTTCTGAAGCCCAC
TAAGGTCTCGGCTCGCCAGCTGCCCCCAAGCGTAGCCAGGGTGGATGCCAAAAGCCGAGTTCTGTTTCCTCTTGGGTTGGGACATGCTGC
TGAGTACGTCAGGCCTCGGGTGGCGCTCATTGGGGATGCAGCCCACAGAGTCCATCCGCTTGCAGGACAGGGTGTCAACATGGGCTTTGG
GGATATCTCCAGCTTGGCCCATCACCTCAGTACGGCAGCCTTCAATGGGAAGGACTTAGGTTCCGTGAGCCACCTCACAGGTTATGAAAC
AGAAAGACAGCGTCACAACACTGCTCTTCTGGCTGCTACAGACTTACTAAAAAGGCTCTATTCTACCAGTGCCTCCCCGCTTGTGTTGCT
CAGGACGTGGGGCTTGCAGGCCACAAATGCAGTGTCTCCACTCAAAGAACAGATTATGGCCTTTGCAAGCAAATGAGTACTCCTCTCCTA
AAGAAAGATTACGTTGATGAAAAAGAACATCCTGCCCAGGACCCATCATACATATTTTCAAGATCTTATTTAATTTAATAAACTTACTTT

>51821_51821_3_MAST2-COQ6_MAST2_chr1_46474043_ENST00000361297_COQ6_chr14_74425674_ENST00000394026_length(amino acids)=590AA_BP=326
MKRSRCRDRPQPPPPDRREDGVQRAAELSQSLPPRRRAPPGRQRLEERTGPAGPEGKEQDVVTGVSPLLFRKLSNPDIFSSTGKVKLQRQ
LSQDDCKLWRGNLASSLSGKQLLPLSSSVHSSVGQVTWQSSGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKSLIVTS
STSPTLPRPHSPLHGHTGNSPLDSPRNFSPNAPAHFSFVPARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADEL
HFLTKHFSTESVPDEEGRQSPAMRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHL
SEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSDADHTDFIDTAGAMLQYAVSLLKPTKVSA
RQLPPSVARVDAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQR

--------------------------------------------------------------
>51821_51821_4_MAST2-COQ6_MAST2_chr1_46474043_ENST00000372009_COQ6_chr14_74425674_ENST00000238709_length(transcript)=2165nt_BP=1261nt
TAGGCAGGCGGCTGAGCCGGCGGCGGGTGGCCTGCCCAACGTGTGCTGGGTGGGAGAAGGCGAGGCGTCAGCGATGCTGTCTCTTCCGTG
AGGAGCGCAGAGGAGGTCGCGGCGCCGGAGGCCCCAGAAGGCTCGAAGGCGCCGCGGGCTGGGGTCGGTGGCTTAGGGAGCCCGTCCGGC
CATGGTGGCCGCGGGTGGTGGTTGGCGCGGCTGCGCTGCGGCCCGGGGCAGTGCGGAGCCGGGACAGTCGCGGCGCTGACGCCCGCGGGC
CCCAGCTGCAGATATGAAGCGGAGCCGCTGCCGCGACCGACCGCAGCCGCCGCCGCCCGACCGCCGGGAGGATGGAGTTCAGCGGGCAGC
GGAGCTGTCTCAGTCTTTGCCGCCGCGCCGGCGAGCGCCGCCCGGGAGGCAGCGGCTGGAGGAGCGGACGGGCCCCGCGGGGCCCGAGGG
CAAGGAGCAGGATGTAGTAACTGGAGTTAGTCCCCTGCTCTTCAGGAAACTCAGTAATCCTGACATATTTTCATCCACTGGAAAAGTTAA
ACTTCAGCGACAACTGAGTCAGGATGATTGTAAGTTATGGAGAGGAAACCTGGCCAGCTCTCTATCGGGTAAGCAGCTGCTCCCTTTGTC
CAGCAGTGTACATAGCAGTGTGGGACAGGTGACTTGGCAGTCGTCAGGAGAAGCATCAAACCTGGTTCGAATGAGAAACCAGTCCCTTGG
ACAGTCTGCACCTTCTCTTACTGCTGGCCTGAAGGAGTTGAGCCTTCCAAGAAGAGGCAGCTTTTGTCGGACAAGTAACCGCAAGAGCTT
GATTGTGACCTCTAGCACATCACCTACACTACCACGGCCACACTCACCACTCCATGGCCACACAGGTAACAGTCCTTTGGACAGCCCCCG
GAATTTCTCTCCAAATGCACCTGCTCACTTTTCTTTTGTTCCTGCCCGTAGGACTGATGGGCGGCGCTGGTCTTTGGCCTCTTTGCCCTC
TTCAGGATATGGAACTAACACTCCTAGCTCCACTGTCTCATCATCATGCTCCTCACAGGAAAAGCTGCATCAGTTGCCTTTCCAGCCTAC
AGCTGATGAGCTGCACTTTTTGACGAAGCATTTCAGCACAGAGAGCGTACCAGATGAGGAAGGACGGCAGTCCCCAGCCATGCGGCCTCG
CTCCCGGAGCCTCAGTCCCGGACGATCCCCAGTATCCTTTGACAGTGAAATAATAATGATGAATCATGTTTACAAAGAAAGATTCCCAAA
GATAGGTGCAGATGGTCACAACTCCGGAGTACGGCAGGCTGTTGGAATCCAGAATGTGAGCTGGAACTATGACCAGTCTGCTGTTGTGGC
TACTCTGCATTTATCAGAGGCCACAGAAAACAACGTAGCCTGGCAGAGATTTCTTCCCTCTGGGCCTATTGCTCTGCTCCCGCTCTCAGA
CACCTTGAGTTCCTTGGTTTGGTCCACGTCCCATGAACATGCAGCAGAGCTAGTTAGCATGGATGAGGAAAAATTTGTGGATGCCGTTAA
CTCTGCCTTTTGGAGTGATGCTGACCACACGGACTTCATCGACACAGCTGGTGCCATGCTGCAGTATGCTGTCAGCCTTCTGAAGCCCAC
TAAGGTCTCGGCTCGCCAGCTGCCCCCAAGCGTAGCCAGGGTGGATGCCAAAAGCCGAGTTCTGTTTCCTCTTGGGTTGGGACATGCTGC
TGAGTACGTCAGGCCTCGGGTGGCGCTCATTGGGGATGCAGCCCACAGAGTCCATCCGCTTGCAGGACAGGGTGTCAACATGGGCTTTGG
GGATATCTCCAGCTTGGCCCATCACCTCAGTACGGCAGCCTTCAATGGGAAGGACTTAGGTTCCGTGAGCCACCTCACAGGTTATGAAAC
AGAAAGACAGCGTCACAACACTGCTCTTCTGGCTGCTACAGACTTACTAAAAAGGCTCTATTCTACCAGTGCCTCCCCGCTTGTGTTGCT
CAGGACGTGGGGCTTGCAGGCCACAAATGCAGTGTCTCCACTCAAAGAACAGATTATGGCCTTTGCAAGCAAATGAGTACTCCTCTCCTA
AAGAAAGATTACGTTGATGAAAAAGAACATCCTGCCCAGGACCCATCATACATATTTTCAAGATCTTATTTAATTTAATAAACTTACTTT

>51821_51821_4_MAST2-COQ6_MAST2_chr1_46474043_ENST00000372009_COQ6_chr14_74425674_ENST00000238709_length(amino acids)=590AA_BP=326
MKRSRCRDRPQPPPPDRREDGVQRAAELSQSLPPRRRAPPGRQRLEERTGPAGPEGKEQDVVTGVSPLLFRKLSNPDIFSSTGKVKLQRQ
LSQDDCKLWRGNLASSLSGKQLLPLSSSVHSSVGQVTWQSSGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKSLIVTS
STSPTLPRPHSPLHGHTGNSPLDSPRNFSPNAPAHFSFVPARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADEL
HFLTKHFSTESVPDEEGRQSPAMRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHL
SEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSDADHTDFIDTAGAMLQYAVSLLKPTKVSA
RQLPPSVARVDAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQR

--------------------------------------------------------------
>51821_51821_5_MAST2-COQ6_MAST2_chr1_46474043_ENST00000372009_COQ6_chr14_74425674_ENST00000334571_length(transcript)=2727nt_BP=1261nt
TAGGCAGGCGGCTGAGCCGGCGGCGGGTGGCCTGCCCAACGTGTGCTGGGTGGGAGAAGGCGAGGCGTCAGCGATGCTGTCTCTTCCGTG
AGGAGCGCAGAGGAGGTCGCGGCGCCGGAGGCCCCAGAAGGCTCGAAGGCGCCGCGGGCTGGGGTCGGTGGCTTAGGGAGCCCGTCCGGC
CATGGTGGCCGCGGGTGGTGGTTGGCGCGGCTGCGCTGCGGCCCGGGGCAGTGCGGAGCCGGGACAGTCGCGGCGCTGACGCCCGCGGGC
CCCAGCTGCAGATATGAAGCGGAGCCGCTGCCGCGACCGACCGCAGCCGCCGCCGCCCGACCGCCGGGAGGATGGAGTTCAGCGGGCAGC
GGAGCTGTCTCAGTCTTTGCCGCCGCGCCGGCGAGCGCCGCCCGGGAGGCAGCGGCTGGAGGAGCGGACGGGCCCCGCGGGGCCCGAGGG
CAAGGAGCAGGATGTAGTAACTGGAGTTAGTCCCCTGCTCTTCAGGAAACTCAGTAATCCTGACATATTTTCATCCACTGGAAAAGTTAA
ACTTCAGCGACAACTGAGTCAGGATGATTGTAAGTTATGGAGAGGAAACCTGGCCAGCTCTCTATCGGGTAAGCAGCTGCTCCCTTTGTC
CAGCAGTGTACATAGCAGTGTGGGACAGGTGACTTGGCAGTCGTCAGGAGAAGCATCAAACCTGGTTCGAATGAGAAACCAGTCCCTTGG
ACAGTCTGCACCTTCTCTTACTGCTGGCCTGAAGGAGTTGAGCCTTCCAAGAAGAGGCAGCTTTTGTCGGACAAGTAACCGCAAGAGCTT
GATTGTGACCTCTAGCACATCACCTACACTACCACGGCCACACTCACCACTCCATGGCCACACAGGTAACAGTCCTTTGGACAGCCCCCG
GAATTTCTCTCCAAATGCACCTGCTCACTTTTCTTTTGTTCCTGCCCGTAGGACTGATGGGCGGCGCTGGTCTTTGGCCTCTTTGCCCTC
TTCAGGATATGGAACTAACACTCCTAGCTCCACTGTCTCATCATCATGCTCCTCACAGGAAAAGCTGCATCAGTTGCCTTTCCAGCCTAC
AGCTGATGAGCTGCACTTTTTGACGAAGCATTTCAGCACAGAGAGCGTACCAGATGAGGAAGGACGGCAGTCCCCAGCCATGCGGCCTCG
CTCCCGGAGCCTCAGTCCCGGACGATCCCCAGTATCCTTTGACAGTGAAATAATAATGATGAATCATGTTTACAAAGAAAGATTCCCAAA
GATAGGTGCAGATGGTCACAACTCCGGAGTACGGCAGGCTGTTGGAATCCAGAATGTGAGCTGGAACTATGACCAGTCTGCTGTTGTGGC
TACTCTGCATTTATCAGAGGCCACAGAAAACAACGTAGCCTGGCAGAGATTTCTTCCCTCTGGGCCTATTGCTCTGCTCCCGCTCTCAGA
CACCTTGAGTTCCTTGGTTTGGTCCACGTCCCATGAACATGCAGCAGAGCTAGTTAGCATGGATGAGGAAAAATTTGTGGATGCCGTTAA
CTCTGCCTTTTGGAGTGATGCTGACCACACGGACTTCATCGACACAGCTGGTGCCATGCTGCAGTATGCTGTCAGCCTTCTGAAGCCCAC
TAAGGTCTCGGCTCGCCAGCTGCCCCCAAGCGTAGCCAGGGTGGATGCCAAAAGCCGAGTTCTGTTTCCTCTTGGGTTGGGACATGCTGC
TGAGTACGTCAGGCCTCGGGTGGCGCTCATTGGGGATGCAGCCCACAGAGTCCATCCGCTTGCAGGACAGGGTGTCAACATGGGCTTTGG
GGATATCTCCAGCTTGGCCCATCACCTCAGTACGGCAGCCTTCAATGGGAAGGACTTAGGTTCCGTGAGCCACCTCACAGGTTATGAAAC
AGAAAGACAGCGTCACAACACTGCTCTTCTGGCTGCTACAGACTTACTAAAAAGGCTCTATTCTACCAGTGCCTCCCCGCTTGTGTTGCT
CAGGACGTGGGGCTTGCAGGCCACAAATGCAGTGTCTCCACTCAAAGAACAGATTATGGCCTTTGCAAGCAAATGAGTACTCCTCTCCTA
AAGAAAGATTACGTTGATGAAAAAGAACATCCTGCCCAGGACCCATCATACATATTTTCAAGATCTTATTTAATTTAATAAACTTACTTT
ACATTAAAATTCTCTTTTTCTTCTTTGCTTAATGGGCCTGTGGCACCCAAATAATGAATGATAATTTGCTGTGAGGAGCGTATATTAGCC
AGACCAAAGGAAAAAACTTCGAAGGAAGACTTACAATTTGGTTGAAAAGAGCTTTTTATTACTAAAAAACCCACAAGGTGCTGTCTCACT
CATTTCCAGTTAATCATTTCTAAAGAGAAAATTTACATTTTGTTTTTGTTTTAATGTTGGTCATAAATTTATACAGTTGTTTTTTGATAG
AGGTAAGAATTAGACTCGATGCATTTTTGTTAGAATTGCTGTTTAAATGTTAACATCAGAATGCAAATTAAATATAAATTGCTTTAACCT
TTGTTACAGGTATACTGGACTTTCTGAAAGGAAAACCAGGTCTCATTAATGCTAGTTATTACTTTATCACAGCACCAGATTTCCATTTTA
TTTATGGTTCCTCTCTGGGACACCACTGTCGGTTTAATAAAACAATAAATAATTCATTGCACAGATCCGAAGACCTCAGGAACCAGATCA

>51821_51821_5_MAST2-COQ6_MAST2_chr1_46474043_ENST00000372009_COQ6_chr14_74425674_ENST00000334571_length(amino acids)=590AA_BP=326
MKRSRCRDRPQPPPPDRREDGVQRAAELSQSLPPRRRAPPGRQRLEERTGPAGPEGKEQDVVTGVSPLLFRKLSNPDIFSSTGKVKLQRQ
LSQDDCKLWRGNLASSLSGKQLLPLSSSVHSSVGQVTWQSSGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKSLIVTS
STSPTLPRPHSPLHGHTGNSPLDSPRNFSPNAPAHFSFVPARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADEL
HFLTKHFSTESVPDEEGRQSPAMRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHL
SEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSDADHTDFIDTAGAMLQYAVSLLKPTKVSA
RQLPPSVARVDAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQR

--------------------------------------------------------------
>51821_51821_6_MAST2-COQ6_MAST2_chr1_46474043_ENST00000372009_COQ6_chr14_74425674_ENST00000394026_length(transcript)=2165nt_BP=1261nt
TAGGCAGGCGGCTGAGCCGGCGGCGGGTGGCCTGCCCAACGTGTGCTGGGTGGGAGAAGGCGAGGCGTCAGCGATGCTGTCTCTTCCGTG
AGGAGCGCAGAGGAGGTCGCGGCGCCGGAGGCCCCAGAAGGCTCGAAGGCGCCGCGGGCTGGGGTCGGTGGCTTAGGGAGCCCGTCCGGC
CATGGTGGCCGCGGGTGGTGGTTGGCGCGGCTGCGCTGCGGCCCGGGGCAGTGCGGAGCCGGGACAGTCGCGGCGCTGACGCCCGCGGGC
CCCAGCTGCAGATATGAAGCGGAGCCGCTGCCGCGACCGACCGCAGCCGCCGCCGCCCGACCGCCGGGAGGATGGAGTTCAGCGGGCAGC
GGAGCTGTCTCAGTCTTTGCCGCCGCGCCGGCGAGCGCCGCCCGGGAGGCAGCGGCTGGAGGAGCGGACGGGCCCCGCGGGGCCCGAGGG
CAAGGAGCAGGATGTAGTAACTGGAGTTAGTCCCCTGCTCTTCAGGAAACTCAGTAATCCTGACATATTTTCATCCACTGGAAAAGTTAA
ACTTCAGCGACAACTGAGTCAGGATGATTGTAAGTTATGGAGAGGAAACCTGGCCAGCTCTCTATCGGGTAAGCAGCTGCTCCCTTTGTC
CAGCAGTGTACATAGCAGTGTGGGACAGGTGACTTGGCAGTCGTCAGGAGAAGCATCAAACCTGGTTCGAATGAGAAACCAGTCCCTTGG
ACAGTCTGCACCTTCTCTTACTGCTGGCCTGAAGGAGTTGAGCCTTCCAAGAAGAGGCAGCTTTTGTCGGACAAGTAACCGCAAGAGCTT
GATTGTGACCTCTAGCACATCACCTACACTACCACGGCCACACTCACCACTCCATGGCCACACAGGTAACAGTCCTTTGGACAGCCCCCG
GAATTTCTCTCCAAATGCACCTGCTCACTTTTCTTTTGTTCCTGCCCGTAGGACTGATGGGCGGCGCTGGTCTTTGGCCTCTTTGCCCTC
TTCAGGATATGGAACTAACACTCCTAGCTCCACTGTCTCATCATCATGCTCCTCACAGGAAAAGCTGCATCAGTTGCCTTTCCAGCCTAC
AGCTGATGAGCTGCACTTTTTGACGAAGCATTTCAGCACAGAGAGCGTACCAGATGAGGAAGGACGGCAGTCCCCAGCCATGCGGCCTCG
CTCCCGGAGCCTCAGTCCCGGACGATCCCCAGTATCCTTTGACAGTGAAATAATAATGATGAATCATGTTTACAAAGAAAGATTCCCAAA
GATAGGTGCAGATGGTCACAACTCCGGAGTACGGCAGGCTGTTGGAATCCAGAATGTGAGCTGGAACTATGACCAGTCTGCTGTTGTGGC
TACTCTGCATTTATCAGAGGCCACAGAAAACAACGTAGCCTGGCAGAGATTTCTTCCCTCTGGGCCTATTGCTCTGCTCCCGCTCTCAGA
CACCTTGAGTTCCTTGGTTTGGTCCACGTCCCATGAACATGCAGCAGAGCTAGTTAGCATGGATGAGGAAAAATTTGTGGATGCCGTTAA
CTCTGCCTTTTGGAGTGATGCTGACCACACGGACTTCATCGACACAGCTGGTGCCATGCTGCAGTATGCTGTCAGCCTTCTGAAGCCCAC
TAAGGTCTCGGCTCGCCAGCTGCCCCCAAGCGTAGCCAGGGTGGATGCCAAAAGCCGAGTTCTGTTTCCTCTTGGGTTGGGACATGCTGC
TGAGTACGTCAGGCCTCGGGTGGCGCTCATTGGGGATGCAGCCCACAGAGTCCATCCGCTTGCAGGACAGGGTGTCAACATGGGCTTTGG
GGATATCTCCAGCTTGGCCCATCACCTCAGTACGGCAGCCTTCAATGGGAAGGACTTAGGTTCCGTGAGCCACCTCACAGGTTATGAAAC
AGAAAGACAGCGTCACAACACTGCTCTTCTGGCTGCTACAGACTTACTAAAAAGGCTCTATTCTACCAGTGCCTCCCCGCTTGTGTTGCT
CAGGACGTGGGGCTTGCAGGCCACAAATGCAGTGTCTCCACTCAAAGAACAGATTATGGCCTTTGCAAGCAAATGAGTACTCCTCTCCTA
AAGAAAGATTACGTTGATGAAAAAGAACATCCTGCCCAGGACCCATCATACATATTTTCAAGATCTTATTTAATTTAATAAACTTACTTT

>51821_51821_6_MAST2-COQ6_MAST2_chr1_46474043_ENST00000372009_COQ6_chr14_74425674_ENST00000394026_length(amino acids)=590AA_BP=326
MKRSRCRDRPQPPPPDRREDGVQRAAELSQSLPPRRRAPPGRQRLEERTGPAGPEGKEQDVVTGVSPLLFRKLSNPDIFSSTGKVKLQRQ
LSQDDCKLWRGNLASSLSGKQLLPLSSSVHSSVGQVTWQSSGEASNLVRMRNQSLGQSAPSLTAGLKELSLPRRGSFCRTSNRKSLIVTS
STSPTLPRPHSPLHGHTGNSPLDSPRNFSPNAPAHFSFVPARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPFQPTADEL
HFLTKHFSTESVPDEEGRQSPAMRPRSRSLSPGRSPVSFDSEIIMMNHVYKERFPKIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHL
SEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSDADHTDFIDTAGAMLQYAVSLLKPTKVSA
RQLPPSVARVDAKSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MAST2-COQ6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MAST2-COQ6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MAST2-COQ6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource