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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:MAX-APOC1 (FusionGDB2 ID:51936)

Fusion Gene Summary for MAX-APOC1

Fusion gene summary

Fusion gene information	Fusion gene name: MAX-APOC1
	Fusion gene ID: 51936
		Hgene	Tgene
	Gene symbol	MAX	APOC1
	Gene ID	4149	341
	Gene name	MYC associated factor X	apolipoprotein C1
	Synonyms	bHLHd4	Apo-CI\|ApoC-I\|apo-CIB\|apoC-IB
	Cytomap	14q23.3	19q13.32
	Type of gene	protein-coding	protein-coding
	Description	protein maxclass D basic helix-loop-helix protein 4	apolipoprotein C-I
	Modification date	20200313	20200313
	UniProtAcc	P61244	P02654
	Ensembl transtripts involved in fusion gene	ENST00000358402, ENST00000358664, ENST00000555419, ENST00000555667, ENST00000556979, ENST00000557277, ENST00000557746, ENST00000246163, ENST00000284165, ENST00000341653, ENST00000555932, ENST00000556443,	ENST00000586638, ENST00000589781, ENST00000252491, ENST00000588750, ENST00000588802, ENST00000592885,
Fusion gene scores	* DoF score	6 X 4 X 6=144	4 X 5 X 3=60
	# samples	6	5
	** MAII score	log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: MAX [Title/Abstract] AND APOC1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	MAX(65544631)-APOC1(45419447), # samples:1
Anticipated loss of major functional domain due to fusion event.	MAX-APOC1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. MAX-APOC1 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF. MAX-APOC1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF. MAX-APOC1 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	MAX	GO:0000122	negative regulation of transcription by RNA polymerase II	8521822
Tgene	APOC1	GO:0010900	negative regulation of phosphatidylcholine catabolic process	2302419
Tgene	APOC1	GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	1917954
Tgene	APOC1	GO:0032375	negative regulation of cholesterol transport	10978346
Tgene	APOC1	GO:0033344	cholesterol efflux	11162594
Tgene	APOC1	GO:0033700	phospholipid efflux	11162594
Tgene	APOC1	GO:0034369	plasma lipoprotein particle remodeling	10978346
Tgene	APOC1	GO:0034382	chylomicron remnant clearance	4020294
Tgene	APOC1	GO:0045717	negative regulation of fatty acid biosynthetic process	15576844
Tgene	APOC1	GO:0045833	negative regulation of lipid metabolic process	182536
Tgene	APOC1	GO:0048261	negative regulation of receptor-mediated endocytosis	1917954
Tgene	APOC1	GO:0050995	negative regulation of lipid catabolic process	15576844
Tgene	APOC1	GO:0051005	negative regulation of lipoprotein lipase activity	15576844

Fusion gene breakpoints across MAX (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across APOC1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	GBM	TCGA-06-5411-01A	MAX	chr14	65544631	-	APOC1	chr19	45419447	+

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Fusion Gene ORF analysis for MAX-APOC1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000358402	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000358402	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000358664	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000358664	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000555419	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000555419	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000555667	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000555667	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000556979	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000556979	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000557277	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000557277	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000557746	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
5CDS-intron	ENST00000557746	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
Frame-shift	ENST00000557277	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
Frame-shift	ENST00000557277	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
Frame-shift	ENST00000557277	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
Frame-shift	ENST00000557277	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000358402	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000358402	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000358402	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000358402	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000358664	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000358664	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000358664	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000358664	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000555419	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000555419	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000555419	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000555419	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000555667	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000555667	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000555667	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000555667	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000556979	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000556979	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000556979	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000556979	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000557746	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000557746	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000557746	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
In-frame	ENST00000557746	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000246163	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000246163	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000246163	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000246163	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000284165	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000284165	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000284165	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000284165	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000341653	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000341653	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000341653	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000341653	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000555932	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000555932	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000555932	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000555932	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000556443	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000556443	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000556443	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-3CDS	ENST00000556443	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-intron	ENST00000246163	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-intron	ENST00000246163	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-intron	ENST00000284165	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-intron	ENST00000284165	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-intron	ENST00000341653	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-intron	ENST00000341653	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-intron	ENST00000555932	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-intron	ENST00000555932	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-intron	ENST00000556443	ENST00000586638	MAX	chr14	65544631	-	APOC1	chr19	45419447	+
intron-intron	ENST00000556443	ENST00000589781	MAX	chr14	65544631	-	APOC1	chr19	45419447	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000358402	MAX	chr14	65544631	-	ENST00000588750	APOC1	chr19	45419447	+	739	433	165	626	153
ENST00000358402	MAX	chr14	65544631	-	ENST00000588802	APOC1	chr19	45419447	+	743	433	165	626	153
ENST00000358402	MAX	chr14	65544631	-	ENST00000252491	APOC1	chr19	45419447	+	746	433	165	626	153
ENST00000358402	MAX	chr14	65544631	-	ENST00000592885	APOC1	chr19	45419447	+	886	433	165	764	199
ENST00000358664	MAX	chr14	65544631	-	ENST00000588750	APOC1	chr19	45419447	+	732	426	131	619	162
ENST00000358664	MAX	chr14	65544631	-	ENST00000588802	APOC1	chr19	45419447	+	736	426	131	619	162
ENST00000358664	MAX	chr14	65544631	-	ENST00000252491	APOC1	chr19	45419447	+	739	426	131	619	162
ENST00000358664	MAX	chr14	65544631	-	ENST00000592885	APOC1	chr19	45419447	+	879	426	131	757	208
ENST00000555419	MAX	chr14	65544631	-	ENST00000588750	APOC1	chr19	45419447	+	493	187	0	380	126
ENST00000555419	MAX	chr14	65544631	-	ENST00000588802	APOC1	chr19	45419447	+	497	187	0	380	126
ENST00000555419	MAX	chr14	65544631	-	ENST00000252491	APOC1	chr19	45419447	+	500	187	0	380	126
ENST00000555419	MAX	chr14	65544631	-	ENST00000592885	APOC1	chr19	45419447	+	640	187	0	518	172
ENST00000556979	MAX	chr14	65544631	-	ENST00000588750	APOC1	chr19	45419447	+	779	473	178	666	162
ENST00000556979	MAX	chr14	65544631	-	ENST00000588802	APOC1	chr19	45419447	+	783	473	178	666	162
ENST00000556979	MAX	chr14	65544631	-	ENST00000252491	APOC1	chr19	45419447	+	786	473	178	666	162
ENST00000556979	MAX	chr14	65544631	-	ENST00000592885	APOC1	chr19	45419447	+	926	473	178	804	208
ENST00000555667	MAX	chr14	65544631	-	ENST00000588750	APOC1	chr19	45419447	+	752	446	178	639	153
ENST00000555667	MAX	chr14	65544631	-	ENST00000588802	APOC1	chr19	45419447	+	756	446	178	639	153
ENST00000555667	MAX	chr14	65544631	-	ENST00000252491	APOC1	chr19	45419447	+	759	446	178	639	153
ENST00000555667	MAX	chr14	65544631	-	ENST00000592885	APOC1	chr19	45419447	+	899	446	178	777	199
ENST00000557746	MAX	chr14	65544631	-	ENST00000588750	APOC1	chr19	45419447	+	752	446	178	639	153
ENST00000557746	MAX	chr14	65544631	-	ENST00000588802	APOC1	chr19	45419447	+	756	446	178	639	153
ENST00000557746	MAX	chr14	65544631	-	ENST00000252491	APOC1	chr19	45419447	+	759	446	178	639	153
ENST00000557746	MAX	chr14	65544631	-	ENST00000592885	APOC1	chr19	45419447	+	899	446	178	777	199

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000358402	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.016381852	0.9836181
ENST00000358402	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.01617163	0.9838284
ENST00000358402	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.016903166	0.98309684
ENST00000358402	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.007614116	0.99238586
ENST00000358664	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.013989004	0.986011
ENST00000358664	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.014023209	0.9859768
ENST00000358664	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.014598333	0.98540163
ENST00000358664	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.008824099	0.9911759
ENST00000555419	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.01840665	0.9815933
ENST00000555419	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.019477991	0.98052204
ENST00000555419	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.020066002	0.979934
ENST00000555419	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.005695161	0.99430484
ENST00000556979	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.01922899	0.980771
ENST00000556979	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.018783115	0.9812169
ENST00000556979	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.019864751	0.98013526
ENST00000556979	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.011185503	0.98881453
ENST00000555667	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.017778834	0.9822212
ENST00000555667	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.01766297	0.982337
ENST00000555667	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.018332597	0.9816674
ENST00000555667	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.007710244	0.9922897
ENST00000557746	ENST00000588750	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.017778834	0.9822212
ENST00000557746	ENST00000588802	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.01766297	0.982337
ENST00000557746	ENST00000252491	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.018332597	0.9816674
ENST00000557746	ENST00000592885	MAX	chr14	65544631	-	APOC1	chr19	45419447	+	0.007710244	0.9922897

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Fusion Genomic Features for MAX-APOC1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MAX-APOC1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:65544631/chr19:45419447)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
MAX P61244	APOC1 P02654
FUNCTION: Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements. {ECO:0000269\|PubMed:26070438}.	FUNCTION: Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein. {ECO:0000269\|PubMed:17339654, ECO:0000303\|PubMed:25160599}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000358402

23_74

152.0

Domain

bHLH

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000358664

23_74

161.0

Domain

bHLH

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000556979

23_74

104.0

Domain

bHLH

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000246163

23_74

97.0

Domain

bHLH

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000284165

23_74

135.0

Domain

bHLH

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000341653

23_74

84.0

Domain

bHLH

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000246163

152_156

97.0

Motif

Note=Nuclear localization signal

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000284165

152_156

135.0

Motif

Note=Nuclear localization signal

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000341653

152_156

84.0

Motif

Note=Nuclear localization signal

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000358402

152_156

152.0

Motif

Note=Nuclear localization signal

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000358664

152_156

161.0

Motif

Note=Nuclear localization signal

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000556979

152_156

104.0

Motif

Note=Nuclear localization signal

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000246163

81_102

97.0

Region

Note=Leucine-zipper

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000284165

81_102

135.0

Region

Note=Leucine-zipper

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000341653

81_102

84.0

Region

Note=Leucine-zipper

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000358402

81_102

152.0

Region

Note=Leucine-zipper

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000358664

81_102

161.0

Region

Note=Leucine-zipper

Hgene

MAX

chr14:65544631

chr19:45419447

ENST00000556979

81_102

104.0

Region

Note=Leucine-zipper

Top

Fusion Gene Sequence for MAX-APOC1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>51936_51936_1_MAX-APOC1_MAX_chr14_65544631_ENST00000358402_APOC1_chr19_45419447_ENST00000252491_length(transcript)=746nt_BP=433nt
TTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTCGGCTTGTTGTTGT
CGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAGCGATAACGAT
GACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCAC
AGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATG
CGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAG
GGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATC
AAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGA
CCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGTGGCCCCAGGTGCC

>51936_51936_1_MAX-APOC1_MAX_chr14_65544631_ENST00000358402_APOC1_chr19_45419447_ENST00000252491_length(amino acids)=153AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG

--------------------------------------------------------------
>51936_51936_2_MAX-APOC1_MAX_chr14_65544631_ENST00000358402_APOC1_chr19_45419447_ENST00000588750_length(transcript)=739nt_BP=433nt
TTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTCGGCTTGTTGTTGT
CGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAGCGATAACGAT
GACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCAC
AGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATG
CGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAG
GGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATC
AAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGA
CCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGTGGCCCCAGGTGCC

>51936_51936_2_MAX-APOC1_MAX_chr14_65544631_ENST00000358402_APOC1_chr19_45419447_ENST00000588750_length(amino acids)=153AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG

--------------------------------------------------------------
>51936_51936_3_MAX-APOC1_MAX_chr14_65544631_ENST00000358402_APOC1_chr19_45419447_ENST00000588802_length(transcript)=743nt_BP=433nt
TTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTCGGCTTGTTGTTGT
CGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAGCGATAACGAT
GACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCAC
AGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATG
CGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAG
GGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATC
AAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGA
CCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGTGGCCCCAGGTGCC

>51936_51936_3_MAX-APOC1_MAX_chr14_65544631_ENST00000358402_APOC1_chr19_45419447_ENST00000588802_length(amino acids)=153AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG

--------------------------------------------------------------
>51936_51936_4_MAX-APOC1_MAX_chr14_65544631_ENST00000358402_APOC1_chr19_45419447_ENST00000592885_length(transcript)=886nt_BP=433nt
TTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTCGGCTTGTTGTTGT
CGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAGCGATAACGAT
GACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCAC
AGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATG
CGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAG
GGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATC
AAACAGAGTGAACTTTCTGCCAAGATGCGGTTAGAACCCTTCCCAGGGCACGGGAGAGCTGGGGTGTGTTTTTGGGTGGAGCCCTGGCAG
ATGGTCCAAGATGAACAGATTGAAAAAAAAACAAGTCCTGGAGAGGCTGACAACATCCCTCTGGTCACACAGCTAGATCTCAAGGGAGTG
GTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAA

>51936_51936_4_MAX-APOC1_MAX_chr14_65544631_ENST00000358402_APOC1_chr19_45419447_ENST00000592885_length(amino acids)=199AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG
PAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMRLEPFPGHGRAGVCFWVEPWQMVQDEQIEKKTSPGEADNIPLVTQL

--------------------------------------------------------------
>51936_51936_5_MAX-APOC1_MAX_chr14_65544631_ENST00000358664_APOC1_chr19_45419447_ENST00000252491_length(transcript)=739nt_BP=426nt
GAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTCGGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCT
CCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGA
GGTTTCAATCTGCGGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGC
GGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATGCGAAGGA
AAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAGGGGACCC
CAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATCAAACAGA
GTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGACCTGAAG
GGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGTGGCCCCAGGTGCCACCAATA

>51936_51936_5_MAX-APOC1_MAX_chr14_65544631_ENST00000358664_APOC1_chr19_45419447_ENST00000252491_length(amino acids)=162AA_BP=98
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKR

--------------------------------------------------------------
>51936_51936_6_MAX-APOC1_MAX_chr14_65544631_ENST00000358664_APOC1_chr19_45419447_ENST00000588750_length(transcript)=732nt_BP=426nt
GAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTCGGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCT
CCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGA
GGTTTCAATCTGCGGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGC
GGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATGCGAAGGA
AAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAGGGGACCC
CAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATCAAACAGA
GTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGACCTGAAG
GGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGTGGCCCCAGGTGCCACCAATA

>51936_51936_6_MAX-APOC1_MAX_chr14_65544631_ENST00000358664_APOC1_chr19_45419447_ENST00000588750_length(amino acids)=162AA_BP=98
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKR

--------------------------------------------------------------
>51936_51936_7_MAX-APOC1_MAX_chr14_65544631_ENST00000358664_APOC1_chr19_45419447_ENST00000588802_length(transcript)=736nt_BP=426nt
GAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTCGGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCT
CCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGA
GGTTTCAATCTGCGGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGC
GGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATGCGAAGGA
AAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAGGGGACCC
CAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATCAAACAGA
GTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGACCTGAAG
GGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGTGGCCCCAGGTGCCACCAATA

>51936_51936_7_MAX-APOC1_MAX_chr14_65544631_ENST00000358664_APOC1_chr19_45419447_ENST00000588802_length(amino acids)=162AA_BP=98
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKR

--------------------------------------------------------------
>51936_51936_8_MAX-APOC1_MAX_chr14_65544631_ENST00000358664_APOC1_chr19_45419447_ENST00000592885_length(transcript)=879nt_BP=426nt
GAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTCGGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCT
CCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAATGAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGA
GGTTTCAATCTGCGGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGC
GGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATGCGAAGGA
AAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAGGGGACCC
CAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATCAAACAGA
GTGAACTTTCTGCCAAGATGCGGTTAGAACCCTTCCCAGGGCACGGGAGAGCTGGGGTGTGTTTTTGGGTGGAGCCCTGGCAGATGGTCC
AAGATGAACAGATTGAAAAAAAAACAAGTCCTGGAGAGGCTGACAACATCCCTCTGGTCACACAGCTAGATCTCAAGGGAGTGGTTTTCA
GAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCA

>51936_51936_8_MAX-APOC1_MAX_chr14_65544631_ENST00000358664_APOC1_chr19_45419447_ENST00000592885_length(amino acids)=208AA_BP=98
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKR
QNALLEQQGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMRLEPFPGHGRAGVCFWVEPWQMVQDEQIEKKTSPGEA

--------------------------------------------------------------
>51936_51936_9_MAX-APOC1_MAX_chr14_65544631_ENST00000555419_APOC1_chr19_45419447_ENST00000252491_length(transcript)=500nt_BP=187nt
ATGAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGAGGTTTCAATCTGCGGCATCCCGGGCCCAAATCCTAGACAAA
GCCACAGAATATATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAG
CAGCAAGGCCCAGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAG
GCTCGGGAACTCATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAG
AAACTCAAGATTGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGAC

>51936_51936_9_MAX-APOC1_MAX_chr14_65544631_ENST00000555419_APOC1_chr19_45419447_ENST00000252491_length(amino acids)=126AA_BP=62
MSDNDDIEVESDEEQPRFQSAASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQGPAPAQGTPDVSSALDKLKEFGNTLEDK

--------------------------------------------------------------
>51936_51936_10_MAX-APOC1_MAX_chr14_65544631_ENST00000555419_APOC1_chr19_45419447_ENST00000588750_length(transcript)=493nt_BP=187nt
ATGAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGAGGTTTCAATCTGCGGCATCCCGGGCCCAAATCCTAGACAAA
GCCACAGAATATATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAG
CAGCAAGGCCCAGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAG
GCTCGGGAACTCATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAG
AAACTCAAGATTGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGAC

>51936_51936_10_MAX-APOC1_MAX_chr14_65544631_ENST00000555419_APOC1_chr19_45419447_ENST00000588750_length(amino acids)=126AA_BP=62
MSDNDDIEVESDEEQPRFQSAASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQGPAPAQGTPDVSSALDKLKEFGNTLEDK

--------------------------------------------------------------
>51936_51936_11_MAX-APOC1_MAX_chr14_65544631_ENST00000555419_APOC1_chr19_45419447_ENST00000588802_length(transcript)=497nt_BP=187nt
ATGAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGAGGTTTCAATCTGCGGCATCCCGGGCCCAAATCCTAGACAAA
GCCACAGAATATATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAG
CAGCAAGGCCCAGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAG
GCTCGGGAACTCATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAG
AAACTCAAGATTGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGAC

>51936_51936_11_MAX-APOC1_MAX_chr14_65544631_ENST00000555419_APOC1_chr19_45419447_ENST00000588802_length(amino acids)=126AA_BP=62
MSDNDDIEVESDEEQPRFQSAASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQGPAPAQGTPDVSSALDKLKEFGNTLEDK

--------------------------------------------------------------
>51936_51936_12_MAX-APOC1_MAX_chr14_65544631_ENST00000555419_APOC1_chr19_45419447_ENST00000592885_length(transcript)=640nt_BP=187nt
ATGAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGAGGTTTCAATCTGCGGCATCCCGGGCCCAAATCCTAGACAAA
GCCACAGAATATATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAG
CAGCAAGGCCCAGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAG
GCTCGGGAACTCATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGTTAGAACCCTTCCCAGGGCACGGGAGAGCTGGGGTG
TGTTTTTGGGTGGAGCCCTGGCAGATGGTCCAAGATGAACAGATTGAAAAAAAAACAAGTCCTGGAGAGGCTGACAACATCCCTCTGGTC
ACACAGCTAGATCTCAAGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGACCTGAAGGGTG
ACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGTGGCCCCAGGTGCCACCAATAAAAA

>51936_51936_12_MAX-APOC1_MAX_chr14_65544631_ENST00000555419_APOC1_chr19_45419447_ENST00000592885_length(amino acids)=172AA_BP=62
MSDNDDIEVESDEEQPRFQSAASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQGPAPAQGTPDVSSALDKLKEFGNTLEDK

--------------------------------------------------------------
>51936_51936_13_MAX-APOC1_MAX_chr14_65544631_ENST00000555667_APOC1_chr19_45419447_ENST00000252491_length(transcript)=759nt_BP=446nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAA
AGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATA
TATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCC
AGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACT
CATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGAT
TGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGT

>51936_51936_13_MAX-APOC1_MAX_chr14_65544631_ENST00000555667_APOC1_chr19_45419447_ENST00000252491_length(amino acids)=153AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG

--------------------------------------------------------------
>51936_51936_14_MAX-APOC1_MAX_chr14_65544631_ENST00000555667_APOC1_chr19_45419447_ENST00000588750_length(transcript)=752nt_BP=446nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAA
AGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATA
TATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCC
AGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACT
CATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGAT
TGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGT

>51936_51936_14_MAX-APOC1_MAX_chr14_65544631_ENST00000555667_APOC1_chr19_45419447_ENST00000588750_length(amino acids)=153AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG

--------------------------------------------------------------
>51936_51936_15_MAX-APOC1_MAX_chr14_65544631_ENST00000555667_APOC1_chr19_45419447_ENST00000588802_length(transcript)=756nt_BP=446nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAA
AGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATA
TATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCC
AGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACT
CATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGAT
TGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGT

>51936_51936_15_MAX-APOC1_MAX_chr14_65544631_ENST00000555667_APOC1_chr19_45419447_ENST00000588802_length(amino acids)=153AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG

--------------------------------------------------------------
>51936_51936_16_MAX-APOC1_MAX_chr14_65544631_ENST00000555667_APOC1_chr19_45419447_ENST00000592885_length(transcript)=899nt_BP=446nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAA
AGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATA
TATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCC
AGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACT
CATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGTTAGAACCCTTCCCAGGGCACGGGAGAGCTGGGGTGTGTTTTTGGGT
GGAGCCCTGGCAGATGGTCCAAGATGAACAGATTGAAAAAAAAACAAGTCCTGGAGAGGCTGACAACATCCCTCTGGTCACACAGCTAGA
TCTCAAGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGACCTGAAGGGTGACATCCCAGGA

>51936_51936_16_MAX-APOC1_MAX_chr14_65544631_ENST00000555667_APOC1_chr19_45419447_ENST00000592885_length(amino acids)=199AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG
PAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMRLEPFPGHGRAGVCFWVEPWQMVQDEQIEKKTSPGEADNIPLVTQL

--------------------------------------------------------------
>51936_51936_17_MAX-APOC1_MAX_chr14_65544631_ENST00000556979_APOC1_chr19_45419447_ENST00000252491_length(transcript)=786nt_BP=473nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGAGGTTTCAATCTGCGGCTGACAAACGGGCTCATCATAATGCACT
GGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGC
CCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCA
GAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAA
CACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATT
TCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAG

>51936_51936_17_MAX-APOC1_MAX_chr14_65544631_ENST00000556979_APOC1_chr19_45419447_ENST00000252491_length(amino acids)=162AA_BP=98
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKR

--------------------------------------------------------------
>51936_51936_18_MAX-APOC1_MAX_chr14_65544631_ENST00000556979_APOC1_chr19_45419447_ENST00000588750_length(transcript)=779nt_BP=473nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGAGGTTTCAATCTGCGGCTGACAAACGGGCTCATCATAATGCACT
GGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGC
CCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCA
GAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAA
CACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATT
TCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAG

>51936_51936_18_MAX-APOC1_MAX_chr14_65544631_ENST00000556979_APOC1_chr19_45419447_ENST00000588750_length(amino acids)=162AA_BP=98
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKR

--------------------------------------------------------------
>51936_51936_19_MAX-APOC1_MAX_chr14_65544631_ENST00000556979_APOC1_chr19_45419447_ENST00000588802_length(transcript)=783nt_BP=473nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGAGGTTTCAATCTGCGGCTGACAAACGGGCTCATCATAATGCACT
GGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGC
CCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCA
GAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAA
CACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATT
TCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAG

>51936_51936_19_MAX-APOC1_MAX_chr14_65544631_ENST00000556979_APOC1_chr19_45419447_ENST00000588802_length(amino acids)=162AA_BP=98
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKR

--------------------------------------------------------------
>51936_51936_20_MAX-APOC1_MAX_chr14_65544631_ENST00000556979_APOC1_chr19_45419447_ENST00000592885_length(transcript)=926nt_BP=473nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGAAGAGCAACCGAGGTTTCAATCTGCGGCTGACAAACGGGCTCATCATAATGCACT
GGAACGAAAACGTAGGGACCACATCAAAGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGC
CCAAATCCTAGACAAAGCCACAGAATATATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCA
GAATGCTCTTCTGGAGCAGCAAGGCCCAGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAA
CACACTGGAGGACAAGGCTCGGGAACTCATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGTTAGAACCCTTCCCAGGGCA
CGGGAGAGCTGGGGTGTGTTTTTGGGTGGAGCCCTGGCAGATGGTCCAAGATGAACAGATTGAAAAAAAAACAAGTCCTGGAGAGGCTGA
CAACATCCCTCTGGTCACACAGCTAGATCTCAAGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCAT
GAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGTGGCCCCAG

>51936_51936_20_MAX-APOC1_MAX_chr14_65544631_ENST00000556979_APOC1_chr19_45419447_ENST00000592885_length(amino acids)=208AA_BP=98
MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKR
QNALLEQQGPAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMRLEPFPGHGRAGVCFWVEPWQMVQDEQIEKKTSPGEA

--------------------------------------------------------------
>51936_51936_21_MAX-APOC1_MAX_chr14_65544631_ENST00000557746_APOC1_chr19_45419447_ENST00000252491_length(transcript)=759nt_BP=446nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAA
AGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATA
TATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCC
AGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACT
CATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGAT
TGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGT

>51936_51936_21_MAX-APOC1_MAX_chr14_65544631_ENST00000557746_APOC1_chr19_45419447_ENST00000252491_length(amino acids)=153AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG

--------------------------------------------------------------
>51936_51936_22_MAX-APOC1_MAX_chr14_65544631_ENST00000557746_APOC1_chr19_45419447_ENST00000588750_length(transcript)=752nt_BP=446nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAA
AGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATA
TATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCC
AGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACT
CATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGAT
TGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGT

>51936_51936_22_MAX-APOC1_MAX_chr14_65544631_ENST00000557746_APOC1_chr19_45419447_ENST00000588750_length(amino acids)=153AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG

--------------------------------------------------------------
>51936_51936_23_MAX-APOC1_MAX_chr14_65544631_ENST00000557746_APOC1_chr19_45419447_ENST00000588802_length(transcript)=756nt_BP=446nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAA
AGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATA
TATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCC
AGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACT
CATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGAT
TGACTCATGAGGACCTGAAGGGTGACATCCCAGGAGGGGCCTCTGAAATTTCCCACACCCCAGCGCCTGTGCTGAGGACTCCCTCCATGT

>51936_51936_23_MAX-APOC1_MAX_chr14_65544631_ENST00000557746_APOC1_chr19_45419447_ENST00000588802_length(amino acids)=153AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG

--------------------------------------------------------------
>51936_51936_24_MAX-APOC1_MAX_chr14_65544631_ENST00000557746_APOC1_chr19_45419447_ENST00000592885_length(transcript)=899nt_BP=446nt
AGTGAGGAGGTGGTTCTTGCCCGTGTTGTGTGTGTGTGTGAGTGAGAGAGCGAGTGAGTGAGTGAGTGAGTGTGTGTGTGGGGGGGACTC
GGCTTGTTGTTGTCGGTGACTTCCCCCTCCCCTTCACCCCTTCCCCTCCCCGCCGCCGCTGCAGTGGCCGCTCCCTGGGCCGTAGGAAAT
GAGCGATAACGATGACATCGAGGTGGAGAGCGACGCTGACAAACGGGCTCATCATAATGCACTGGAACGAAAACGTAGGGACCACATCAA
AGACAGCTTTCACAGTTTGCGGGACTCAGTCCCATCACTCCAAGGAGAGAAGGCATCCCGGGCCCAAATCCTAGACAAAGCCACAGAATA
TATCCAGTATATGCGAAGGAAAAACCACACACACCAGCAAGATATTGACGACCTCAAGCGGCAGAATGCTCTTCTGGAGCAGCAAGGCCC
AGCCCCAGCCCAGGGGACCCCAGACGTCTCCAGTGCCTTGGATAAGCTGAAGGAGTTTGGAAACACACTGGAGGACAAGGCTCGGGAACT
CATCAGCCGCATCAAACAGAGTGAACTTTCTGCCAAGATGCGGTTAGAACCCTTCCCAGGGCACGGGAGAGCTGGGGTGTGTTTTTGGGT
GGAGCCCTGGCAGATGGTCCAAGATGAACAGATTGAAAAAAAAACAAGTCCTGGAGAGGCTGACAACATCCCTCTGGTCACACAGCTAGA
TCTCAAGGGAGTGGTTTTCAGAGACATTTCAGAAAGTGAAGGAGAAACTCAAGATTGACTCATGAGGACCTGAAGGGTGACATCCCAGGA

>51936_51936_24_MAX-APOC1_MAX_chr14_65544631_ENST00000557746_APOC1_chr19_45419447_ENST00000592885_length(amino acids)=199AA_BP=89
MSDNDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQG
PAPAQGTPDVSSALDKLKEFGNTLEDKARELISRIKQSELSAKMRLEPFPGHGRAGVCFWVEPWQMVQDEQIEKKTSPGEADNIPLVTQL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for MAX-APOC1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for MAX-APOC1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for MAX-APOC1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source