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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MB21D1-BTRC (FusionGDB2 ID:51946)

Fusion Gene Summary for MB21D1-BTRC

check button Fusion gene summary
Fusion gene informationFusion gene name: MB21D1-BTRC
Fusion gene ID: 51946
HgeneTgene
Gene symbol

MB21D1

BTRC

Gene ID

115004

8945

Gene namecyclic GMP-AMP synthasebeta-transducin repeat containing E3 ubiquitin protein ligase
SynonymsC6orf150|MB21D1|h-cGASBETA-TRCP|FBW1A|FBXW1|FBXW1A|FWD1|bTrCP|bTrCP1|betaTrCP
Cytomap

6q13

10q24.32

Type of geneprotein-codingprotein-coding
Descriptioncyclic GMP-AMP synthase2'3'-cGAMP synthaseMab-21 domain containing 1cGAMP synthasemab-21 domain-containing protein 1protein MB21D1F-box/WD repeat-containing protein 1AE3RSIkappaBF-box and WD repeats protein beta-TrCPF-box and WD-repeat protein 1Bbeta-TrCP1epididymis tissue protein Li 2apIkappaBalpha-E3 receptor subunit
Modification date2020032920200327
UniProtAcc.

Q9Y297

Ensembl transtripts involved in fusion geneENST00000370315, ENST00000370318, 
ENST00000493877, ENST00000370187, 
ENST00000393441, ENST00000408038, 
Fusion gene scores* DoF score4 X 4 X 2=323 X 3 X 3=27
# samples 43
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: MB21D1 [Title/Abstract] AND BTRC [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMB21D1(74161247)-BTRC(103281395), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMB21D1

GO:0002218

activation of innate immune response

23929945|24077100|26046437|28363908|30007416

HgeneMB21D1

GO:0002230

positive regulation of defense response to virus by host

23929945|24077100|26046437

HgeneMB21D1

GO:0006974

cellular response to DNA damage stimulus

28738408

HgeneMB21D1

GO:0010753

positive regulation of cGMP-mediated signaling

23258413|24077100|28738408

HgeneMB21D1

GO:0032481

positive regulation of type I interferon production

24077100|26046437|28363908|28738408

HgeneMB21D1

GO:0038001

paracrine signaling

24077100

HgeneMB21D1

GO:0043950

positive regulation of cAMP-mediated signaling

23258413|24077100|28738408|30007416

HgeneMB21D1

GO:0051607

defense response to virus

21478870|23929945|24077100|26046437

HgeneMB21D1

GO:0071360

cellular response to exogenous dsRNA

23258413|24077100|28214358|28363908

HgeneMB21D1

GO:2000042

negative regulation of double-strand break repair via homologous recombination

30356214

TgeneBTRC

GO:0000209

protein polyubiquitination

12820959

TgeneBTRC

GO:0006511

ubiquitin-dependent protein catabolic process

15448698

TgeneBTRC

GO:0016567

protein ubiquitination

16885022|18354482

TgeneBTRC

GO:0042752

regulation of circadian rhythm

15917222

TgeneBTRC

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

15917222


check buttonFusion gene breakpoints across MB21D1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BTRC (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-VR-A8EWMB21D1chr6

74161247

-BTRCchr10

103281395

+


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Fusion Gene ORF analysis for MB21D1-BTRC

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000370315ENST00000493877MB21D1chr6

74161247

-BTRCchr10

103281395

+
5CDS-intronENST00000370318ENST00000493877MB21D1chr6

74161247

-BTRCchr10

103281395

+
In-frameENST00000370315ENST00000370187MB21D1chr6

74161247

-BTRCchr10

103281395

+
In-frameENST00000370315ENST00000393441MB21D1chr6

74161247

-BTRCchr10

103281395

+
In-frameENST00000370315ENST00000408038MB21D1chr6

74161247

-BTRCchr10

103281395

+
In-frameENST00000370318ENST00000370187MB21D1chr6

74161247

-BTRCchr10

103281395

+
In-frameENST00000370318ENST00000393441MB21D1chr6

74161247

-BTRCchr10

103281395

+
In-frameENST00000370318ENST00000408038MB21D1chr6

74161247

-BTRCchr10

103281395

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000370318MB21D1chr674161247-ENST00000370187BTRCchr10103281395+6427735242228734
ENST00000370318MB21D1chr674161247-ENST00000393441BTRCchr10103281395+6403735242228734
ENST00000370318MB21D1chr674161247-ENST00000408038BTRCchr10103281395+6427735242228734
ENST00000370315MB21D1chr674161247-ENST00000370187BTRCchr10103281395+644475282245745
ENST00000370315MB21D1chr674161247-ENST00000393441BTRCchr10103281395+642075282245745
ENST00000370315MB21D1chr674161247-ENST00000408038BTRCchr10103281395+644475282245745

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000370318ENST00000370187MB21D1chr674161247-BTRCchr10103281395+0.0015856270.9984144
ENST00000370318ENST00000393441MB21D1chr674161247-BTRCchr10103281395+0.0016146010.9983854
ENST00000370318ENST00000408038MB21D1chr674161247-BTRCchr10103281395+0.0015856270.9984144
ENST00000370315ENST00000370187MB21D1chr674161247-BTRCchr10103281395+0.0015753950.99842465
ENST00000370315ENST00000393441MB21D1chr674161247-BTRCchr10103281395+0.0016066050.99839336
ENST00000370315ENST00000408038MB21D1chr674161247-BTRCchr10103281395+0.0015753950.99842465

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Fusion Genomic Features for MB21D1-BTRC


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MB21D1-BTRC


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:74161247/chr10:103281395)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.BTRC

Q9Y297

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds to phosphorylated target proteins (PubMed:10066435, PubMed:10497169, PubMed:10644755, PubMed:10835356, PubMed:11238952, PubMed:11359933, PubMed:11994270, PubMed:12791267, PubMed:12902344, PubMed:14603323, PubMed:14681206, PubMed:14988407, PubMed:15448698, PubMed:15917222, PubMed:16371461, PubMed:25503564, PubMed:25704143, PubMed:9859996, PubMed:22087322). SCF(BTRC) mediates the ubiquitination of CTNNB1 and participates in Wnt signaling (PubMed:12077367, PubMed:12820959). SCF(BTRC) mediates the ubiquitination of phosphorylated NFKB1, ATF4, CDC25A, DLG1, FBXO5, PER1, SMAD3, SMAD4, SNAI1 and probably NFKB2 (PubMed:10835356, PubMed:11238952, PubMed:14681206, PubMed:14603323). SCF(BTRC) mediates the ubiquitination of NFKBIA, NFKBIB and NFKBIE; the degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription (PubMed:10066435, PubMed:10497169, PubMed:10644755). Ubiquitination of NFKBIA occurs at 'Lys-21' and 'Lys-22' (PubMed:10066435). SCF(BTRC) mediates the ubiquitination of CEP68; this is required for centriole separation during mitosis (PubMed:25704143, PubMed:25503564). SCF(BTRC) mediates the ubiquitination and subsequent degradation of nuclear NFE2L1 (By similarity). Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and PER2 (PubMed:15917222). May be involved in ubiquitination and subsequent proteasomal degradation through a DBB1-CUL4 E3 ubiquitin-protein ligase. Required for activation of NFKB-mediated transcription by IL1B, MAP3K14, MAP3K1, IKBKB and TNF. Required for proteolytic processing of GLI3 (PubMed:16371461). Mediates ubiquitination of REST, thereby leading to its proteasomal degradation (PubMed:21258371, PubMed:18354482). {ECO:0000250|UniProtKB:Q3ULA2, ECO:0000269|PubMed:10066435, ECO:0000269|PubMed:10497169, ECO:0000269|PubMed:10644755, ECO:0000269|PubMed:10835356, ECO:0000269|PubMed:11238952, ECO:0000269|PubMed:11359933, ECO:0000269|PubMed:11994270, ECO:0000269|PubMed:12077367, ECO:0000269|PubMed:12791267, ECO:0000269|PubMed:12820959, ECO:0000269|PubMed:12902344, ECO:0000269|PubMed:14603323, ECO:0000269|PubMed:14681206, ECO:0000269|PubMed:14988407, ECO:0000269|PubMed:15448698, ECO:0000269|PubMed:15917222, ECO:0000269|PubMed:16371461, ECO:0000269|PubMed:18354482, ECO:0000269|PubMed:21258371, ECO:0000269|PubMed:22087322, ECO:0000269|PubMed:25503564, ECO:0000269|PubMed:25704143, ECO:0000269|PubMed:9859996}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370315-15120_160219523.0RegionRequired for activation upon DNA viral infection
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370315-15173_215219523.0RegionDNA-binding
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370315-151_160219523.0RegionDNA-binding
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370315-1564_75219523.0RegionRequired for association with the cell membrane
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370318-16120_160219448.0RegionRequired for activation upon DNA viral infection
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370318-16173_215219448.0RegionDNA-binding
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370318-161_160219448.0RegionDNA-binding
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370318-1664_75219448.0RegionRequired for association with the cell membrane
TgeneBTRCchr6:74161247chr10:103281395ENST00000370187315128_1771081939.6666666666667RegionNote=Homodimerization domain D
TgeneBTRCchr6:74161247chr10:103281395ENST00000370187315190_2281081939.6666666666667RegionNote=Required for down-regulation of SNAI1
TgeneBTRCchr6:74161247chr10:103281395ENST00000408038214128_177721918.3333333333333RegionNote=Homodimerization domain D
TgeneBTRCchr6:74161247chr10:103281395ENST00000408038214190_228721918.3333333333333RegionNote=Required for down-regulation of SNAI1
TgeneBTRCchr6:74161247chr10:103281395ENST00000370187315301_3381081939.6666666666667RepeatNote=WD 1
TgeneBTRCchr6:74161247chr10:103281395ENST00000370187315341_3781081939.6666666666667RepeatNote=WD 2
TgeneBTRCchr6:74161247chr10:103281395ENST00000370187315381_4181081939.6666666666667RepeatNote=WD 3
TgeneBTRCchr6:74161247chr10:103281395ENST00000370187315424_4611081939.6666666666667RepeatNote=WD 4
TgeneBTRCchr6:74161247chr10:103281395ENST00000370187315464_5031081939.6666666666667RepeatNote=WD 5
TgeneBTRCchr6:74161247chr10:103281395ENST00000370187315505_5411081939.6666666666667RepeatNote=WD 6
TgeneBTRCchr6:74161247chr10:103281395ENST00000370187315553_5901081939.6666666666667RepeatNote=WD 7
TgeneBTRCchr6:74161247chr10:103281395ENST00000408038214301_338721918.3333333333333RepeatNote=WD 1
TgeneBTRCchr6:74161247chr10:103281395ENST00000408038214341_378721918.3333333333333RepeatNote=WD 2
TgeneBTRCchr6:74161247chr10:103281395ENST00000408038214381_418721918.3333333333333RepeatNote=WD 3
TgeneBTRCchr6:74161247chr10:103281395ENST00000408038214424_461721918.3333333333333RepeatNote=WD 4
TgeneBTRCchr6:74161247chr10:103281395ENST00000408038214464_503721918.3333333333333RepeatNote=WD 5
TgeneBTRCchr6:74161247chr10:103281395ENST00000408038214505_541721918.3333333333333RepeatNote=WD 6
TgeneBTRCchr6:74161247chr10:103281395ENST00000408038214553_590721918.3333333333333RepeatNote=WD 7

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370315-15376_383219523.0Nucleotide bindingGTP
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370315-15380_383219523.0Nucleotide bindingATP
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370315-15435_439219523.0Nucleotide bindingATP
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370318-16376_383219448.0Nucleotide bindingGTP
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370318-16380_383219448.0Nucleotide bindingATP
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370318-16435_439219448.0Nucleotide bindingATP
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370315-15384_407219523.0RegionDNA-binding
HgeneMB21D1chr6:74161247chr10:103281395ENST00000370318-16384_407219448.0RegionDNA-binding


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Fusion Gene Sequence for MB21D1-BTRC


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>51946_51946_1_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370315_BTRC_chr10_103281395_ENST00000370187_length(transcript)=6444nt_BP=752nt
AGTAGTGCTTGGTTTCCAACAGCTGCTGCTGGCTCTTCCTCTTGCGGCCTTTTCCTGAAACGGATTCTTCTTTCGGGGAACAGAAAGCGC
CAGCCATGCAGCCTTGGCACGGAAAGGCCATGCAGAGAGCTTCCGAGGCCGGAGCCACTGCCCCCAAGGCTTCCGCACGGAATGCCAGGG
GCGCCCCGATGGATCCCACCGAGTCTCCGGCTGCCCCCGAGGCCGCCCTGCCTAAGGCGGGAAAGTTCGGCCCCGCCAGGAAGTCGGGAT
CCCGGCAGAAAAAGAGCGCCCCGGACACCCAGGAGAGGCCGCCCGTCCGCGCAACTGGGGCCCGCGCCAAAAAGGCCCCTCAGCGCGCCC
AGGACACGCAGCCGTCTGACGCCACCAGCGCCCCTGGGGCAGAGGGGCTGGAGCCTCCTGCGGCTCGGGAGCCGGCTCTTTCCAGGGCTG
GTTCTTGCCGCCAGAGGGGCGCGCGCTGCTCCACGAAGCCAAGACCTCCGCCCGGGCCCTGGGACGTGCCCAGCCCCGGCCTGCCGGTCT
CGGCCCCCATTCTCGTACGGAGGGATGCGGCGCCTGGGGCCTCGAAGCTCCGGGCGGTTTTGGAGAAGTTGAAGCTCAGCCGCGATGATA
TCTCCACGGCGGCGGGGATGGTGAAAGGGGTTGTGGACCACCTGCTGCTCAGACTGAAGTGCGACTCCGCGTTCAGAGGCGTCGGGCTGC
TGAACACCGGGAGCTACTATGAGCACGTGAAGACAAAACTTGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAACGGAAACTCTCAG
CAAGCTATGAAAAGGAAAAGGAACTGTGTGTCAAATACTTTGAGCAGTGGTCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATAT
CCCAAATGTGTCATTACCAACATGGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCTCTGCCAGCTCGGG
GATTGGATCATATTGCTGAGAACATTCTGTCATACCTGGATGCCAAATCACTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAG
TGACCTCTGATGGCATGCTGTGGAAGAAGCTTATCGAGAGAATGGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCAGAACGAAGAGGAT
GGGGACAGTATTTATTCAAAAACAAACCTCCTGACGGGAATGCTCCTCCCAACTCTTTTTATAGAGCACTTTATCCTAAAATTATACAAG
ACATTGAGACAATAGAATCTAATTGGAGATGTGGAAGACATAGTTTACAGAGAATTCACTGCCGAAGTGAAACAAGCAAAGGAGTTTACT
GTTTACAGTATGATGATCAGAAAATAGTAAGCGGCCTTCGAGACAACACAATCAAGATCTGGGATAAAAACACATTGGAATGCAAGCGAA
TTCTCACAGGCCATACAGGTTCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCATCGGATTCCACGGTCAGAGTGT
GGGATGTAAATACAGGTGAAATGCTAAACACGTTGATTCACCATTGTGAAGCAGTTCTGCACTTGCGTTTCAATAATGGCATGATGGTGA
CCTGCTCCAAAGATCGTTCCATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGGGTGCTGGTCGGACACCGAGCTG
CTGTCAATGTTGTAGACTTTGATGACAAGTACATTGTTTCTGCATCTGGGGATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAAT
TTGTAAGGACCTTAAATGGACACAAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTGAGTGGCTCATCTGACAACACTA
TCAGATTATGGGACATAGAATGTGGTGCATGTTTACGAGTGTTAGAAGGCCATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGA
GGATAGTCAGTGGGGCCTATGATGGAAAAATTAAAGTGTGGGATCTTGTGGCTGCTTTGGACCCCCGTGCTCCTGCAGGGACACTCTGTC
TACGGACCCTTGTGGAGCATTCCGGAAGAGTTTTTCGACTACAGTTTGATGAATTCCAGATTGTCAGTAGTTCACATGATGACACAATCC
TCATCTGGGACTTCCTAAATGATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCCTTCTCGAACATACACCTACATCTCCAGATAAATAA
CCATACACTGACCTCATACTTGCCCAGGACCCATTAAAGTTGCGGTATTTAACGTATCTGCCAATACCAGGATGAGCAACAACAGTAACA
ATCAAACTACTGCCCAGTTTCCCTGGACTAGCCGAGGAGCAGGGCTTTGAGACTCCTGTTGGGACACAGTTGGTCTGCAGTCGGCCCAGG
ACGGTCTACTCAGCACAACTGACTGCTTCAGTGCTGCTATCAGAAGATGTCTTCTATCTTTTGTGAATGATTGGAACTTTTAAACCTCCC
CTCCTCTCCTCCTTTCACCTCTGCACCTAGTTTTTTCCCATTGGTTCCAGACAAAGGTGACTTATAAATATATTTAGTGTTTTGCCAGAA
TCTCTCTTGCTTTGCCATTAAGCAGAAGAACTAGTTTCCCTGTATAGCCTGCTGGGAGAGACCCACTTCTAGGGTATGGGGGATGCAGCT
TCAAGCCCAGTGCCCAGTGTCTCCCTGTTAACTGCAGGAATGCCAAGCACCTGGCCAGAGCAGCCCAGCCCCAATATGCTTAGGAGGAGA
CAGAGTTCCCTCTGTATAGCCTCTGGGACAAGAAAAAGAAAACACAAGAATGTATACACTGGAAGATTTGGGCCTCCTGCCTGCCTTCTC
TTTGTTTCTGTTCCTCTTCCCATCTACTCCCCTACGCCCCTTCAACCTTTTTTCTCTGTCTGCTTCACCTGAGAAGAAAGTGTACGAAGA
GAGTGTCCTCCTCTCACATGAGCCAGATCAGCCAGAAAATGCAACACTTGGAAGAGTTAAATGCTGTTCAGTGAAGATTTCAGCCCCAGG
CCTTTGCTGCAAGTGACCCTGTGGCAACAGTGGATTCTCAGACATGATACTCTCATCATATTTGCAACTCTTCTCTCTCTTTCTTCCCCA
CACCCAAGAGGAGGATTGGTGGTAGGGGGCAGGCAGAGGGGGTGGGGAGAAGTTTCCTGGGCTCCATCAATGGCTGCATCTTTTCTGGAC
TCAGCAGTCTCCTTGATTCCATGTAGAGTGTGGAAAGGAGTTGCTGATTGCATTTCCTCTCATTAACAATTGGGTGTGTAATAAAAAGCA
TTGTACTTCATCTTAAATCACTGGTAAGGCTCAGCCTACAGAAAGATTTGAAATGGCCAGAGCCAATCGCTTGGTGCATTCTGCGTAATG
GTTTCCATCTCCGATTTCCTCATCAGGGCCTGTGAATACCCAGGTGCCTGTATCTTTGCCAAGACCGTGATCAAGGTAGCTTAAGAGAGA
TGGTCAGGAGAAAACACTGTTTTTGTTTTTTTTGTTGTTTTGTTTTGTTTTGGCCAGTTAAATATCATCTCTCAAATATTGATCTCACCG
TGTCAACCTTGCACTGCACAACCTTCCTTCTGCTTCTCCCACACCCAGTATTTGCAGAAGGGCAAAGCTGCTTAAGAGAGAGGATCAGGG
TGAAGTTTGGCACACAGGGTTTATTAATGGGGCAAAAACTGCCTTTTCTTCCTCCTCCTGACCTTATTTTGCTCTTCACTCTCCCCAGCC
AATAAAGCGTCTGTGGCGATTGGTGAACAGCATAAACAGCTGGACCTCAGCAAGGGTCAGGCAAACCCAGTCACTCGGAAGGCAGCTGTG
TGAGCTGCCAAGCTAGTGGGCTTCAGGTGCAAGGGTACCTGTGCCACACCAACCTGGGAGCACACAGAATACTATTAATGTGCACCCAGC
TGGTCTCCCCAGGCAAGAAGGTATCCTCTTCCCAAGGTGTACCCACTGAATGTTGTTACTACATATTGAGAGTCATTTTATGCATATGCA
TTCTACCTTTCCTGCTTTATGAGTATTTTTAAGCTTTTAGTTCAAGGTTATATTCAGAAAATATTTCCCAGTATAATGATACATCGTAGC
CTAAGAAATATTTTCTCAATGTAATTCCCTTCCCAGCTACCCAAATGCTACAGAGAAATGTTTTCTACTTGGCCACTATCAGGGTTCGTC
ATCTATTGTGTTGACTATTAATGGCTTTTTGATTGGGTAAGGATTTTGCTATAGATGAAGGTAGAGGGCTGTCAGCCCTGAAAAACACAC
AGGTCAGACATTTAAAAGGCATGGGTTTCGAGCTGTCTCAAAATATTGCCCAATAGCCATAATTTTACCAGCCTTTCTGTCATATGCTGC
TATTACAAAGTGGAAGCTGTTGAATGTTTATTGGTGCCCAGGGTTTTGCTCTCCAATCTAGGTTCAGTTGAAGGAATATTGTTTCTAAGA
CTGTTTTGAGACATGTCCAGTACATCACAAAGGAGATCGGGGCGACCCCTGCAGATGTGGAGCCATTAGCCCAGTTGAGGATATTCTCCA
AGTTGTCCTCTCTCCTGCTGATGGAAATGGGAATGAAGTTAAGTGGTCTGAAAAACTTGAATCGTTCACATTTCTCAGCTCTGGGGGTCA
TTTACCAGTTTGTTGTAGAAGAAATAATCAGGTAAGTTAAAAGTTCATTTCCAGAGAAGGTAAACCCCACTTACCATCTCTGCATGATTT
CAGTGGGAATTGATTATCACTAATCCCCAACTGGGCTAGAATAAATGTAAAGTTTGACCTTTTTAAAACGAAAAGAGAGACAAAGTCTCA
GCACATTCCAAGGAGTGGTAGAAACAGAGCTGAAGGTGTCCCCATTGTAGATTAGTCTCTTCTCACTAAAATTTACTTTCCAACGTAGGG
CCTAAAGGAAACCTTTCTTAAAGACAGGCTGAAACCCCTTCAAAGGCAGATGAGGAGGTACAGACACGTGACCTTTTGGTGCACACTGGA
GCTACTTGGACAAGACCAGCATGCCTTGCTGCACGTGTGTGTATTTCACTGCTGAGAACATCCTTTAACTTGGTGTGCAATTTGAAAGGA
TGTGAATCATGGATGGAAGGCCATTTGTACATGTCCCTTGGCAAAATTCTTTCTGGTGTCTCCTAACTTCAGAGACAGGGACTCTTTTTG
GATCTCTATTGACAAGTAATAAAAGTCTGGCCCTCATAACTTGTTTCCGAACTAGAAAAGTCTGTGAGACCCCTACATCATTCTGGTTTT
TTTGCTTGAGTAAGAACAATCCTTTTTTATTTTTCTTCTGTACAGTCTAAAGCTACAGAGAAAAAAAAATGCACTCTTCCCTTGCCGGCT
CCTGGTACCATTGGTCTGAACAGCTGTAGTTGGTCTACTCCTTACTTAGCACTTGATTGTGTGGGGAAACAAAGGTGGGAGGGGTGGGGA
ATACTGGAAATAATCAGGGCAATTTTTTTCTTTCCCATAATTGGACTAGATACCTTGGTACTGTTGACCTTCTCAGCATCTCCCTTTTGC
CTTAGATGGCAACACCCTCCAGTCTGTAGCAGAGCAGTCCAACCCAGATTAGTGCAGCCCGGAGGCTTAGGGTGCAGCCTCCCTGGTCTT
CCTCCACACAGTTGTTCACCAACAGACCAGACCTCCTTTAACCACAGTGTCAACATAGTATCGGAAAGAGAGCCATTTCTTAGGGGAATA
AAACAGTTTCGCTTCTTTAGCTCATCTGTGGTGTCAGAATCCTTGGAGCTGAAGAGAGAAATCAAAAGAGCATGATGATGGCTGCCTGGT
TTCAGGTGGAACTTAATGCATTGATCTTTAGAAGCTCCTTCTGTTGGAAGTTGAGTACCTGTGATCTAAAATGTCCTGGAGGCAGATGAC
ATCTAAAATATGTGCTTTCCAACCAGCACAGCTGGCGCTCTTAGCTCCTGATTGGTTGTGTGTTTTATTAAGGATCAGTGCAGTTAAGTC
GTATTTTAAAGTGTTACCTCCCCTCCTAACCCTTCCCCTTCTTGGACACTGAAGGAAAAGGCCAACTAGGGTGTTAGCCCTCTGGGCACC
AAGGAAACTAACAGCTTTCTCAAAGCGGTGACCACTCAGGCCAGCCCAGACAAATCTGAGGGATGGCCAGTGCACTCCAATGATGGGACA
GGCCTAACAACACATGTAAGCTTCCCCGAGAGCTTTCAGCTGGTTCACCTCTTTGTTCTCTAGACTCTTAAGTACTGACTGCTTTGACTT
TTGTGATTATGTTATGGTGATGTGTAGTCAGTGTACCAATATGTTCACAACCTAGGATCATGATAATGGAGTGTGTTTTGGGTTTTTTTT

>51946_51946_1_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370315_BTRC_chr10_103281395_ENST00000370187_length(amino acids)=745AA_BP=248
MVSNSCCWLFLLRPFPETDSSFGEQKAPAMQPWHGKAMQRASEAGATAPKASARNARGAPMDPTESPAAPEAALPKAGKFGPARKSGSRQ
KKSAPDTQERPPVRATGARAKKAPQRAQDTQPSDATSAPGAEGLEPPAAREPALSRAGSCRQRGARCSTKPRPPPGPWDVPSPGLPVSAP
ILVRRDAAPGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKTKLANGTSSMIVPKQRKLSASY
EKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTS
DGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQ
YDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCS
KDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRL
WDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIW

--------------------------------------------------------------
>51946_51946_2_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370315_BTRC_chr10_103281395_ENST00000393441_length(transcript)=6420nt_BP=752nt
AGTAGTGCTTGGTTTCCAACAGCTGCTGCTGGCTCTTCCTCTTGCGGCCTTTTCCTGAAACGGATTCTTCTTTCGGGGAACAGAAAGCGC
CAGCCATGCAGCCTTGGCACGGAAAGGCCATGCAGAGAGCTTCCGAGGCCGGAGCCACTGCCCCCAAGGCTTCCGCACGGAATGCCAGGG
GCGCCCCGATGGATCCCACCGAGTCTCCGGCTGCCCCCGAGGCCGCCCTGCCTAAGGCGGGAAAGTTCGGCCCCGCCAGGAAGTCGGGAT
CCCGGCAGAAAAAGAGCGCCCCGGACACCCAGGAGAGGCCGCCCGTCCGCGCAACTGGGGCCCGCGCCAAAAAGGCCCCTCAGCGCGCCC
AGGACACGCAGCCGTCTGACGCCACCAGCGCCCCTGGGGCAGAGGGGCTGGAGCCTCCTGCGGCTCGGGAGCCGGCTCTTTCCAGGGCTG
GTTCTTGCCGCCAGAGGGGCGCGCGCTGCTCCACGAAGCCAAGACCTCCGCCCGGGCCCTGGGACGTGCCCAGCCCCGGCCTGCCGGTCT
CGGCCCCCATTCTCGTACGGAGGGATGCGGCGCCTGGGGCCTCGAAGCTCCGGGCGGTTTTGGAGAAGTTGAAGCTCAGCCGCGATGATA
TCTCCACGGCGGCGGGGATGGTGAAAGGGGTTGTGGACCACCTGCTGCTCAGACTGAAGTGCGACTCCGCGTTCAGAGGCGTCGGGCTGC
TGAACACCGGGAGCTACTATGAGCACGTGAAGACAAAACTTGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAACGGAAACTCTCAG
CAAGCTATGAAAAGGAAAAGGAACTGTGTGTCAAATACTTTGAGCAGTGGTCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATAT
CCCAAATGTGTCATTACCAACATGGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCTCTGCCAGCTCGGG
GATTGGATCATATTGCTGAGAACATTCTGTCATACCTGGATGCCAAATCACTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAG
TGACCTCTGATGGCATGCTGTGGAAGAAGCTTATCGAGAGAATGGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCAGAACGAAGAGGAT
GGGGACAGTATTTATTCAAAAACAAACCTCCTGACGGGAATGCTCCTCCCAACTCTTTTTATAGAGCACTTTATCCTAAAATTATACAAG
ACATTGAGACAATAGAATCTAATTGGAGATGTGGAAGACATAGTTTACAGAGAATTCACTGCCGAAGTGAAACAAGCAAAGGAGTTTACT
GTTTACAGTATGATGATCAGAAAATAGTAAGCGGCCTTCGAGACAACACAATCAAGATCTGGGATAAAAACACATTGGAATGCAAGCGAA
TTCTCACAGGCCATACAGGTTCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCATCGGATTCCACGGTCAGAGTGT
GGGATGTAAATACAGGTGAAATGCTAAACACGTTGATTCACCATTGTGAAGCAGTTCTGCACTTGCGTTTCAATAATGGCATGATGGTGA
CCTGCTCCAAAGATCGTTCCATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGGGTGCTGGTCGGACACCGAGCTG
CTGTCAATGTTGTAGACTTTGATGACAAGTACATTGTTTCTGCATCTGGGGATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAAT
TTGTAAGGACCTTAAATGGACACAAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTGAGTGGCTCATCTGACAACACTA
TCAGATTATGGGACATAGAATGTGGTGCATGTTTACGAGTGTTAGAAGGCCATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGA
GGATAGTCAGTGGGGCCTATGATGGAAAAATTAAAGTGTGGGATCTTGTGGCTGCTTTGGACCCCCGTGCTCCTGCAGGGACACTCTGTC
TACGGACCCTTGTGGAGCATTCCGGAAGAGTTTTTCGACTACAGTTTGATGAATTCCAGATTGTCAGTAGTTCACATGATGACACAATCC
TCATCTGGGACTTCCTAAATGATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCCTTCTCGAACATACACCTACATCTCCAGATAAATAA
CCATACACTGACCTCATACTTGCCCAGGACCCATTAAAGTTGCGGTATTTAACGTATCTGCCAATACCAGGATGAGCAACAACAGTAACA
ATCAAACTACTGCCCAGTTTCCCTGGACTAGCCGAGGAGCAGGGCTTTGAGACTCCTGTTGGGACACAGTTGGTCTGCAGTCGGCCCAGG
ACGGTCTACTCAGCACAACTGACTGCTTCAGTGCTGCTATCAGAAGATGTCTTCTATCTTTTGTGAATGATTGGAACTTTTAAACCTCCC
CTCCTCTCCTCCTTTCACCTCTGCACCTAGTTTTTTCCCATTGGTTCCAGACAAAGGTGACTTATAAATATATTTAGTGTTTTGCCAGAA
TCTCTCTTGCTTTGCCATTAAGCAGAAGAACTAGTTTCCCTGTATAGCCTGCTGGGAGAGACCCACTTCTAGGGTATGGGGGATGCAGCT
TCAAGCCCAGTGCCCAGTGTCTCCCTGTTAACTGCAGGAATGCCAAGCACCTGGCCAGAGCAGCCCAGCCCCAATATGCTTAGGAGGAGA
CAGAGTTCCCTCTGTATAGCCTCTGGGACAAGAAAAAGAAAACACAAGAATGTATACACTGGAAGATTTGGGCCTCCTGCCTGCCTTCTC
TTTGTTTCTGTTCCTCTTCCCATCTACTCCCCTACGCCCCTTCAACCTTTTTTCTCTGTCTGCTTCACCTGAGAAGAAAGTGTACGAAGA
GAGTGTCCTCCTCTCACATGAGCCAGATCAGCCAGAAAATGCAACACTTGGAAGAGTTAAATGCTGTTCAGTGAAGATTTCAGCCCCAGG
CCTTTGCTGCAAGTGACCCTGTGGCAACAGTGGATTCTCAGACATGATACTCTCATCATATTTGCAACTCTTCTCTCTCTTTCTTCCCCA
CACCCAAGAGGAGGATTGGTGGTAGGGGGCAGGCAGAGGGGGTGGGGAGAAGTTTCCTGGGCTCCATCAATGGCTGCATCTTTTCTGGAC
TCAGCAGTCTCCTTGATTCCATGTAGAGTGTGGAAAGGAGTTGCTGATTGCATTTCCTCTCATTAACAATTGGGTGTGTAATAAAAAGCA
TTGTACTTCATCTTAAATCACTGGTAAGGCTCAGCCTACAGAAAGATTTGAAATGGCCAGAGCCAATCGCTTGGTGCATTCTGCGTAATG
GTTTCCATCTCCGATTTCCTCATCAGGGCCTGTGAATACCCAGGTGCCTGTATCTTTGCCAAGACCGTGATCAAGGTAGCTTAAGAGAGA
TGGTCAGGAGAAAACACTGTTTTTGTTTTTTTTGTTGTTTTGTTTTGTTTTGGCCAGTTAAATATCATCTCTCAAATATTGATCTCACCG
TGTCAACCTTGCACTGCACAACCTTCCTTCTGCTTCTCCCACACCCAGTATTTGCAGAAGGGCAAAGCTGCTTAAGAGAGAGGATCAGGG
TGAAGTTTGGCACACAGGGTTTATTAATGGGGCAAAAACTGCCTTTTCTTCCTCCTCCTGACCTTATTTTGCTCTTCACTCTCCCCAGCC
AATAAAGCGTCTGTGGCGATTGGTGAACAGCATAAACAGCTGGACCTCAGCAAGGGTCAGGCAAACCCAGTCACTCGGAAGGCAGCTGTG
TGAGCTGCCAAGCTAGTGGGCTTCAGGTGCAAGGGTACCTGTGCCACACCAACCTGGGAGCACACAGAATACTATTAATGTGCACCCAGC
TGGTCTCCCCAGGCAAGAAGGTATCCTCTTCCCAAGGTGTACCCACTGAATGTTGTTACTACATATTGAGAGTCATTTTATGCATATGCA
TTCTACCTTTCCTGCTTTATGAGTATTTTTAAGCTTTTAGTTCAAGGTTATATTCAGAAAATATTTCCCAGTATAATGATACATCGTAGC
CTAAGAAATATTTTCTCAATGTAATTCCCTTCCCAGCTACCCAAATGCTACAGAGAAATGTTTTCTACTTGGCCACTATCAGGGTTCGTC
ATCTATTGTGTTGACTATTAATGGCTTTTTGATTGGGTAAGGATTTTGCTATAGATGAAGGTAGAGGGCTGTCAGCCCTGAAAAACACAC
AGGTCAGACATTTAAAAGGCATGGGTTTCGAGCTGTCTCAAAATATTGCCCAATAGCCATAATTTTACCAGCCTTTCTGTCATATGCTGC
TATTACAAAGTGGAAGCTGTTGAATGTTTATTGGTGCCCAGGGTTTTGCTCTCCAATCTAGGTTCAGTTGAAGGAATATTGTTTCTAAGA
CTGTTTTGAGACATGTCCAGTACATCACAAAGGAGATCGGGGCGACCCCTGCAGATGTGGAGCCATTAGCCCAGTTGAGGATATTCTCCA
AGTTGTCCTCTCTCCTGCTGATGGAAATGGGAATGAAGTTAAGTGGTCTGAAAAACTTGAATCGTTCACATTTCTCAGCTCTGGGGGTCA
TTTACCAGTTTGTTGTAGAAGAAATAATCAGGTAAGTTAAAAGTTCATTTCCAGAGAAGGTAAACCCCACTTACCATCTCTGCATGATTT
CAGTGGGAATTGATTATCACTAATCCCCAACTGGGCTAGAATAAATGTAAAGTTTGACCTTTTTAAAACGAAAAGAGAGACAAAGTCTCA
GCACATTCCAAGGAGTGGTAGAAACAGAGCTGAAGGTGTCCCCATTGTAGATTAGTCTCTTCTCACTAAAATTTACTTTCCAACGTAGGG
CCTAAAGGAAACCTTTCTTAAAGACAGGCTGAAACCCCTTCAAAGGCAGATGAGGAGGTACAGACACGTGACCTTTTGGTGCACACTGGA
GCTACTTGGACAAGACCAGCATGCCTTGCTGCACGTGTGTGTATTTCACTGCTGAGAACATCCTTTAACTTGGTGTGCAATTTGAAAGGA
TGTGAATCATGGATGGAAGGCCATTTGTACATGTCCCTTGGCAAAATTCTTTCTGGTGTCTCCTAACTTCAGAGACAGGGACTCTTTTTG
GATCTCTATTGACAAGTAATAAAAGTCTGGCCCTCATAACTTGTTTCCGAACTAGAAAAGTCTGTGAGACCCCTACATCATTCTGGTTTT
TTTGCTTGAGTAAGAACAATCCTTTTTTATTTTTCTTCTGTACAGTCTAAAGCTACAGAGAAAAAAAAATGCACTCTTCCCTTGCCGGCT
CCTGGTACCATTGGTCTGAACAGCTGTAGTTGGTCTACTCCTTACTTAGCACTTGATTGTGTGGGGAAACAAAGGTGGGAGGGGTGGGGA
ATACTGGAAATAATCAGGGCAATTTTTTTCTTTCCCATAATTGGACTAGATACCTTGGTACTGTTGACCTTCTCAGCATCTCCCTTTTGC
CTTAGATGGCAACACCCTCCAGTCTGTAGCAGAGCAGTCCAACCCAGATTAGTGCAGCCCGGAGGCTTAGGGTGCAGCCTCCCTGGTCTT
CCTCCACACAGTTGTTCACCAACAGACCAGACCTCCTTTAACCACAGTGTCAACATAGTATCGGAAAGAGAGCCATTTCTTAGGGGAATA
AAACAGTTTCGCTTCTTTAGCTCATCTGTGGTGTCAGAATCCTTGGAGCTGAAGAGAGAAATCAAAAGAGCATGATGATGGCTGCCTGGT
TTCAGGTGGAACTTAATGCATTGATCTTTAGAAGCTCCTTCTGTTGGAAGTTGAGTACCTGTGATCTAAAATGTCCTGGAGGCAGATGAC
ATCTAAAATATGTGCTTTCCAACCAGCACAGCTGGCGCTCTTAGCTCCTGATTGGTTGTGTGTTTTATTAAGGATCAGTGCAGTTAAGTC
GTATTTTAAAGTGTTACCTCCCCTCCTAACCCTTCCCCTTCTTGGACACTGAAGGAAAAGGCCAACTAGGGTGTTAGCCCTCTGGGCACC
AAGGAAACTAACAGCTTTCTCAAAGCGGTGACCACTCAGGCCAGCCCAGACAAATCTGAGGGATGGCCAGTGCACTCCAATGATGGGACA
GGCCTAACAACACATGTAAGCTTCCCCGAGAGCTTTCAGCTGGTTCACCTCTTTGTTCTCTAGACTCTTAAGTACTGACTGCTTTGACTT
TTGTGATTATGTTATGGTGATGTGTAGTCAGTGTACCAATATGTTCACAACCTAGGATCATGATAATGGAGTGTGTTTTGGGTTTTTTTT

>51946_51946_2_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370315_BTRC_chr10_103281395_ENST00000393441_length(amino acids)=745AA_BP=248
MVSNSCCWLFLLRPFPETDSSFGEQKAPAMQPWHGKAMQRASEAGATAPKASARNARGAPMDPTESPAAPEAALPKAGKFGPARKSGSRQ
KKSAPDTQERPPVRATGARAKKAPQRAQDTQPSDATSAPGAEGLEPPAAREPALSRAGSCRQRGARCSTKPRPPPGPWDVPSPGLPVSAP
ILVRRDAAPGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKTKLANGTSSMIVPKQRKLSASY
EKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTS
DGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQ
YDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCS
KDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRL
WDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIW

--------------------------------------------------------------
>51946_51946_3_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370315_BTRC_chr10_103281395_ENST00000408038_length(transcript)=6444nt_BP=752nt
AGTAGTGCTTGGTTTCCAACAGCTGCTGCTGGCTCTTCCTCTTGCGGCCTTTTCCTGAAACGGATTCTTCTTTCGGGGAACAGAAAGCGC
CAGCCATGCAGCCTTGGCACGGAAAGGCCATGCAGAGAGCTTCCGAGGCCGGAGCCACTGCCCCCAAGGCTTCCGCACGGAATGCCAGGG
GCGCCCCGATGGATCCCACCGAGTCTCCGGCTGCCCCCGAGGCCGCCCTGCCTAAGGCGGGAAAGTTCGGCCCCGCCAGGAAGTCGGGAT
CCCGGCAGAAAAAGAGCGCCCCGGACACCCAGGAGAGGCCGCCCGTCCGCGCAACTGGGGCCCGCGCCAAAAAGGCCCCTCAGCGCGCCC
AGGACACGCAGCCGTCTGACGCCACCAGCGCCCCTGGGGCAGAGGGGCTGGAGCCTCCTGCGGCTCGGGAGCCGGCTCTTTCCAGGGCTG
GTTCTTGCCGCCAGAGGGGCGCGCGCTGCTCCACGAAGCCAAGACCTCCGCCCGGGCCCTGGGACGTGCCCAGCCCCGGCCTGCCGGTCT
CGGCCCCCATTCTCGTACGGAGGGATGCGGCGCCTGGGGCCTCGAAGCTCCGGGCGGTTTTGGAGAAGTTGAAGCTCAGCCGCGATGATA
TCTCCACGGCGGCGGGGATGGTGAAAGGGGTTGTGGACCACCTGCTGCTCAGACTGAAGTGCGACTCCGCGTTCAGAGGCGTCGGGCTGC
TGAACACCGGGAGCTACTATGAGCACGTGAAGACAAAACTTGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAACGGAAACTCTCAG
CAAGCTATGAAAAGGAAAAGGAACTGTGTGTCAAATACTTTGAGCAGTGGTCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATAT
CCCAAATGTGTCATTACCAACATGGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCTCTGCCAGCTCGGG
GATTGGATCATATTGCTGAGAACATTCTGTCATACCTGGATGCCAAATCACTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAG
TGACCTCTGATGGCATGCTGTGGAAGAAGCTTATCGAGAGAATGGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCAGAACGAAGAGGAT
GGGGACAGTATTTATTCAAAAACAAACCTCCTGACGGGAATGCTCCTCCCAACTCTTTTTATAGAGCACTTTATCCTAAAATTATACAAG
ACATTGAGACAATAGAATCTAATTGGAGATGTGGAAGACATAGTTTACAGAGAATTCACTGCCGAAGTGAAACAAGCAAAGGAGTTTACT
GTTTACAGTATGATGATCAGAAAATAGTAAGCGGCCTTCGAGACAACACAATCAAGATCTGGGATAAAAACACATTGGAATGCAAGCGAA
TTCTCACAGGCCATACAGGTTCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCATCGGATTCCACGGTCAGAGTGT
GGGATGTAAATACAGGTGAAATGCTAAACACGTTGATTCACCATTGTGAAGCAGTTCTGCACTTGCGTTTCAATAATGGCATGATGGTGA
CCTGCTCCAAAGATCGTTCCATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGGGTGCTGGTCGGACACCGAGCTG
CTGTCAATGTTGTAGACTTTGATGACAAGTACATTGTTTCTGCATCTGGGGATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAAT
TTGTAAGGACCTTAAATGGACACAAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTGAGTGGCTCATCTGACAACACTA
TCAGATTATGGGACATAGAATGTGGTGCATGTTTACGAGTGTTAGAAGGCCATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGA
GGATAGTCAGTGGGGCCTATGATGGAAAAATTAAAGTGTGGGATCTTGTGGCTGCTTTGGACCCCCGTGCTCCTGCAGGGACACTCTGTC
TACGGACCCTTGTGGAGCATTCCGGAAGAGTTTTTCGACTACAGTTTGATGAATTCCAGATTGTCAGTAGTTCACATGATGACACAATCC
TCATCTGGGACTTCCTAAATGATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCCTTCTCGAACATACACCTACATCTCCAGATAAATAA
CCATACACTGACCTCATACTTGCCCAGGACCCATTAAAGTTGCGGTATTTAACGTATCTGCCAATACCAGGATGAGCAACAACAGTAACA
ATCAAACTACTGCCCAGTTTCCCTGGACTAGCCGAGGAGCAGGGCTTTGAGACTCCTGTTGGGACACAGTTGGTCTGCAGTCGGCCCAGG
ACGGTCTACTCAGCACAACTGACTGCTTCAGTGCTGCTATCAGAAGATGTCTTCTATCTTTTGTGAATGATTGGAACTTTTAAACCTCCC
CTCCTCTCCTCCTTTCACCTCTGCACCTAGTTTTTTCCCATTGGTTCCAGACAAAGGTGACTTATAAATATATTTAGTGTTTTGCCAGAA
TCTCTCTTGCTTTGCCATTAAGCAGAAGAACTAGTTTCCCTGTATAGCCTGCTGGGAGAGACCCACTTCTAGGGTATGGGGGATGCAGCT
TCAAGCCCAGTGCCCAGTGTCTCCCTGTTAACTGCAGGAATGCCAAGCACCTGGCCAGAGCAGCCCAGCCCCAATATGCTTAGGAGGAGA
CAGAGTTCCCTCTGTATAGCCTCTGGGACAAGAAAAAGAAAACACAAGAATGTATACACTGGAAGATTTGGGCCTCCTGCCTGCCTTCTC
TTTGTTTCTGTTCCTCTTCCCATCTACTCCCCTACGCCCCTTCAACCTTTTTTCTCTGTCTGCTTCACCTGAGAAGAAAGTGTACGAAGA
GAGTGTCCTCCTCTCACATGAGCCAGATCAGCCAGAAAATGCAACACTTGGAAGAGTTAAATGCTGTTCAGTGAAGATTTCAGCCCCAGG
CCTTTGCTGCAAGTGACCCTGTGGCAACAGTGGATTCTCAGACATGATACTCTCATCATATTTGCAACTCTTCTCTCTCTTTCTTCCCCA
CACCCAAGAGGAGGATTGGTGGTAGGGGGCAGGCAGAGGGGGTGGGGAGAAGTTTCCTGGGCTCCATCAATGGCTGCATCTTTTCTGGAC
TCAGCAGTCTCCTTGATTCCATGTAGAGTGTGGAAAGGAGTTGCTGATTGCATTTCCTCTCATTAACAATTGGGTGTGTAATAAAAAGCA
TTGTACTTCATCTTAAATCACTGGTAAGGCTCAGCCTACAGAAAGATTTGAAATGGCCAGAGCCAATCGCTTGGTGCATTCTGCGTAATG
GTTTCCATCTCCGATTTCCTCATCAGGGCCTGTGAATACCCAGGTGCCTGTATCTTTGCCAAGACCGTGATCAAGGTAGCTTAAGAGAGA
TGGTCAGGAGAAAACACTGTTTTTGTTTTTTTTGTTGTTTTGTTTTGTTTTGGCCAGTTAAATATCATCTCTCAAATATTGATCTCACCG
TGTCAACCTTGCACTGCACAACCTTCCTTCTGCTTCTCCCACACCCAGTATTTGCAGAAGGGCAAAGCTGCTTAAGAGAGAGGATCAGGG
TGAAGTTTGGCACACAGGGTTTATTAATGGGGCAAAAACTGCCTTTTCTTCCTCCTCCTGACCTTATTTTGCTCTTCACTCTCCCCAGCC
AATAAAGCGTCTGTGGCGATTGGTGAACAGCATAAACAGCTGGACCTCAGCAAGGGTCAGGCAAACCCAGTCACTCGGAAGGCAGCTGTG
TGAGCTGCCAAGCTAGTGGGCTTCAGGTGCAAGGGTACCTGTGCCACACCAACCTGGGAGCACACAGAATACTATTAATGTGCACCCAGC
TGGTCTCCCCAGGCAAGAAGGTATCCTCTTCCCAAGGTGTACCCACTGAATGTTGTTACTACATATTGAGAGTCATTTTATGCATATGCA
TTCTACCTTTCCTGCTTTATGAGTATTTTTAAGCTTTTAGTTCAAGGTTATATTCAGAAAATATTTCCCAGTATAATGATACATCGTAGC
CTAAGAAATATTTTCTCAATGTAATTCCCTTCCCAGCTACCCAAATGCTACAGAGAAATGTTTTCTACTTGGCCACTATCAGGGTTCGTC
ATCTATTGTGTTGACTATTAATGGCTTTTTGATTGGGTAAGGATTTTGCTATAGATGAAGGTAGAGGGCTGTCAGCCCTGAAAAACACAC
AGGTCAGACATTTAAAAGGCATGGGTTTCGAGCTGTCTCAAAATATTGCCCAATAGCCATAATTTTACCAGCCTTTCTGTCATATGCTGC
TATTACAAAGTGGAAGCTGTTGAATGTTTATTGGTGCCCAGGGTTTTGCTCTCCAATCTAGGTTCAGTTGAAGGAATATTGTTTCTAAGA
CTGTTTTGAGACATGTCCAGTACATCACAAAGGAGATCGGGGCGACCCCTGCAGATGTGGAGCCATTAGCCCAGTTGAGGATATTCTCCA
AGTTGTCCTCTCTCCTGCTGATGGAAATGGGAATGAAGTTAAGTGGTCTGAAAAACTTGAATCGTTCACATTTCTCAGCTCTGGGGGTCA
TTTACCAGTTTGTTGTAGAAGAAATAATCAGGTAAGTTAAAAGTTCATTTCCAGAGAAGGTAAACCCCACTTACCATCTCTGCATGATTT
CAGTGGGAATTGATTATCACTAATCCCCAACTGGGCTAGAATAAATGTAAAGTTTGACCTTTTTAAAACGAAAAGAGAGACAAAGTCTCA
GCACATTCCAAGGAGTGGTAGAAACAGAGCTGAAGGTGTCCCCATTGTAGATTAGTCTCTTCTCACTAAAATTTACTTTCCAACGTAGGG
CCTAAAGGAAACCTTTCTTAAAGACAGGCTGAAACCCCTTCAAAGGCAGATGAGGAGGTACAGACACGTGACCTTTTGGTGCACACTGGA
GCTACTTGGACAAGACCAGCATGCCTTGCTGCACGTGTGTGTATTTCACTGCTGAGAACATCCTTTAACTTGGTGTGCAATTTGAAAGGA
TGTGAATCATGGATGGAAGGCCATTTGTACATGTCCCTTGGCAAAATTCTTTCTGGTGTCTCCTAACTTCAGAGACAGGGACTCTTTTTG
GATCTCTATTGACAAGTAATAAAAGTCTGGCCCTCATAACTTGTTTCCGAACTAGAAAAGTCTGTGAGACCCCTACATCATTCTGGTTTT
TTTGCTTGAGTAAGAACAATCCTTTTTTATTTTTCTTCTGTACAGTCTAAAGCTACAGAGAAAAAAAAATGCACTCTTCCCTTGCCGGCT
CCTGGTACCATTGGTCTGAACAGCTGTAGTTGGTCTACTCCTTACTTAGCACTTGATTGTGTGGGGAAACAAAGGTGGGAGGGGTGGGGA
ATACTGGAAATAATCAGGGCAATTTTTTTCTTTCCCATAATTGGACTAGATACCTTGGTACTGTTGACCTTCTCAGCATCTCCCTTTTGC
CTTAGATGGCAACACCCTCCAGTCTGTAGCAGAGCAGTCCAACCCAGATTAGTGCAGCCCGGAGGCTTAGGGTGCAGCCTCCCTGGTCTT
CCTCCACACAGTTGTTCACCAACAGACCAGACCTCCTTTAACCACAGTGTCAACATAGTATCGGAAAGAGAGCCATTTCTTAGGGGAATA
AAACAGTTTCGCTTCTTTAGCTCATCTGTGGTGTCAGAATCCTTGGAGCTGAAGAGAGAAATCAAAAGAGCATGATGATGGCTGCCTGGT
TTCAGGTGGAACTTAATGCATTGATCTTTAGAAGCTCCTTCTGTTGGAAGTTGAGTACCTGTGATCTAAAATGTCCTGGAGGCAGATGAC
ATCTAAAATATGTGCTTTCCAACCAGCACAGCTGGCGCTCTTAGCTCCTGATTGGTTGTGTGTTTTATTAAGGATCAGTGCAGTTAAGTC
GTATTTTAAAGTGTTACCTCCCCTCCTAACCCTTCCCCTTCTTGGACACTGAAGGAAAAGGCCAACTAGGGTGTTAGCCCTCTGGGCACC
AAGGAAACTAACAGCTTTCTCAAAGCGGTGACCACTCAGGCCAGCCCAGACAAATCTGAGGGATGGCCAGTGCACTCCAATGATGGGACA
GGCCTAACAACACATGTAAGCTTCCCCGAGAGCTTTCAGCTGGTTCACCTCTTTGTTCTCTAGACTCTTAAGTACTGACTGCTTTGACTT
TTGTGATTATGTTATGGTGATGTGTAGTCAGTGTACCAATATGTTCACAACCTAGGATCATGATAATGGAGTGTGTTTTGGGTTTTTTTT

>51946_51946_3_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370315_BTRC_chr10_103281395_ENST00000408038_length(amino acids)=745AA_BP=248
MVSNSCCWLFLLRPFPETDSSFGEQKAPAMQPWHGKAMQRASEAGATAPKASARNARGAPMDPTESPAAPEAALPKAGKFGPARKSGSRQ
KKSAPDTQERPPVRATGARAKKAPQRAQDTQPSDATSAPGAEGLEPPAAREPALSRAGSCRQRGARCSTKPRPPPGPWDVPSPGLPVSAP
ILVRRDAAPGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKTKLANGTSSMIVPKQRKLSASY
EKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTS
DGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQ
YDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCS
KDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRL
WDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIW

--------------------------------------------------------------
>51946_51946_4_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370318_BTRC_chr10_103281395_ENST00000370187_length(transcript)=6427nt_BP=735nt
AACAGCTGCTGCTGGCTCTTCCTCTTGCGGCCTTTTCCTGAAACGGATTCTTCTTTCGGGGAACAGAAAGCGCCAGCCATGCAGCCTTGG
CACGGAAAGGCCATGCAGAGAGCTTCCGAGGCCGGAGCCACTGCCCCCAAGGCTTCCGCACGGAATGCCAGGGGCGCCCCGATGGATCCC
ACCGAGTCTCCGGCTGCCCCCGAGGCCGCCCTGCCTAAGGCGGGAAAGTTCGGCCCCGCCAGGAAGTCGGGATCCCGGCAGAAAAAGAGC
GCCCCGGACACCCAGGAGAGGCCGCCCGTCCGCGCAACTGGGGCCCGCGCCAAAAAGGCCCCTCAGCGCGCCCAGGACACGCAGCCGTCT
GACGCCACCAGCGCCCCTGGGGCAGAGGGGCTGGAGCCTCCTGCGGCTCGGGAGCCGGCTCTTTCCAGGGCTGGTTCTTGCCGCCAGAGG
GGCGCGCGCTGCTCCACGAAGCCAAGACCTCCGCCCGGGCCCTGGGACGTGCCCAGCCCCGGCCTGCCGGTCTCGGCCCCCATTCTCGTA
CGGAGGGATGCGGCGCCTGGGGCCTCGAAGCTCCGGGCGGTTTTGGAGAAGTTGAAGCTCAGCCGCGATGATATCTCCACGGCGGCGGGG
ATGGTGAAAGGGGTTGTGGACCACCTGCTGCTCAGACTGAAGTGCGACTCCGCGTTCAGAGGCGTCGGGCTGCTGAACACCGGGAGCTAC
TATGAGCACGTGAAGACAAAACTTGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAACGGAAACTCTCAGCAAGCTATGAAAAGGAA
AAGGAACTGTGTGTCAAATACTTTGAGCAGTGGTCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATATCCCAAATGTGTCATTAC
CAACATGGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCTCTGCCAGCTCGGGGATTGGATCATATTGCT
GAGAACATTCTGTCATACCTGGATGCCAAATCACTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAGTGACCTCTGATGGCATG
CTGTGGAAGAAGCTTATCGAGAGAATGGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCAGAACGAAGAGGATGGGGACAGTATTTATTC
AAAAACAAACCTCCTGACGGGAATGCTCCTCCCAACTCTTTTTATAGAGCACTTTATCCTAAAATTATACAAGACATTGAGACAATAGAA
TCTAATTGGAGATGTGGAAGACATAGTTTACAGAGAATTCACTGCCGAAGTGAAACAAGCAAAGGAGTTTACTGTTTACAGTATGATGAT
CAGAAAATAGTAAGCGGCCTTCGAGACAACACAATCAAGATCTGGGATAAAAACACATTGGAATGCAAGCGAATTCTCACAGGCCATACA
GGTTCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCATCGGATTCCACGGTCAGAGTGTGGGATGTAAATACAGGT
GAAATGCTAAACACGTTGATTCACCATTGTGAAGCAGTTCTGCACTTGCGTTTCAATAATGGCATGATGGTGACCTGCTCCAAAGATCGT
TCCATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGGGTGCTGGTCGGACACCGAGCTGCTGTCAATGTTGTAGAC
TTTGATGACAAGTACATTGTTTCTGCATCTGGGGATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAATTTGTAAGGACCTTAAAT
GGACACAAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTGAGTGGCTCATCTGACAACACTATCAGATTATGGGACATA
GAATGTGGTGCATGTTTACGAGTGTTAGAAGGCCATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGAGGATAGTCAGTGGGGCC
TATGATGGAAAAATTAAAGTGTGGGATCTTGTGGCTGCTTTGGACCCCCGTGCTCCTGCAGGGACACTCTGTCTACGGACCCTTGTGGAG
CATTCCGGAAGAGTTTTTCGACTACAGTTTGATGAATTCCAGATTGTCAGTAGTTCACATGATGACACAATCCTCATCTGGGACTTCCTA
AATGATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCCTTCTCGAACATACACCTACATCTCCAGATAAATAACCATACACTGACCTCAT
ACTTGCCCAGGACCCATTAAAGTTGCGGTATTTAACGTATCTGCCAATACCAGGATGAGCAACAACAGTAACAATCAAACTACTGCCCAG
TTTCCCTGGACTAGCCGAGGAGCAGGGCTTTGAGACTCCTGTTGGGACACAGTTGGTCTGCAGTCGGCCCAGGACGGTCTACTCAGCACA
ACTGACTGCTTCAGTGCTGCTATCAGAAGATGTCTTCTATCTTTTGTGAATGATTGGAACTTTTAAACCTCCCCTCCTCTCCTCCTTTCA
CCTCTGCACCTAGTTTTTTCCCATTGGTTCCAGACAAAGGTGACTTATAAATATATTTAGTGTTTTGCCAGAATCTCTCTTGCTTTGCCA
TTAAGCAGAAGAACTAGTTTCCCTGTATAGCCTGCTGGGAGAGACCCACTTCTAGGGTATGGGGGATGCAGCTTCAAGCCCAGTGCCCAG
TGTCTCCCTGTTAACTGCAGGAATGCCAAGCACCTGGCCAGAGCAGCCCAGCCCCAATATGCTTAGGAGGAGACAGAGTTCCCTCTGTAT
AGCCTCTGGGACAAGAAAAAGAAAACACAAGAATGTATACACTGGAAGATTTGGGCCTCCTGCCTGCCTTCTCTTTGTTTCTGTTCCTCT
TCCCATCTACTCCCCTACGCCCCTTCAACCTTTTTTCTCTGTCTGCTTCACCTGAGAAGAAAGTGTACGAAGAGAGTGTCCTCCTCTCAC
ATGAGCCAGATCAGCCAGAAAATGCAACACTTGGAAGAGTTAAATGCTGTTCAGTGAAGATTTCAGCCCCAGGCCTTTGCTGCAAGTGAC
CCTGTGGCAACAGTGGATTCTCAGACATGATACTCTCATCATATTTGCAACTCTTCTCTCTCTTTCTTCCCCACACCCAAGAGGAGGATT
GGTGGTAGGGGGCAGGCAGAGGGGGTGGGGAGAAGTTTCCTGGGCTCCATCAATGGCTGCATCTTTTCTGGACTCAGCAGTCTCCTTGAT
TCCATGTAGAGTGTGGAAAGGAGTTGCTGATTGCATTTCCTCTCATTAACAATTGGGTGTGTAATAAAAAGCATTGTACTTCATCTTAAA
TCACTGGTAAGGCTCAGCCTACAGAAAGATTTGAAATGGCCAGAGCCAATCGCTTGGTGCATTCTGCGTAATGGTTTCCATCTCCGATTT
CCTCATCAGGGCCTGTGAATACCCAGGTGCCTGTATCTTTGCCAAGACCGTGATCAAGGTAGCTTAAGAGAGATGGTCAGGAGAAAACAC
TGTTTTTGTTTTTTTTGTTGTTTTGTTTTGTTTTGGCCAGTTAAATATCATCTCTCAAATATTGATCTCACCGTGTCAACCTTGCACTGC
ACAACCTTCCTTCTGCTTCTCCCACACCCAGTATTTGCAGAAGGGCAAAGCTGCTTAAGAGAGAGGATCAGGGTGAAGTTTGGCACACAG
GGTTTATTAATGGGGCAAAAACTGCCTTTTCTTCCTCCTCCTGACCTTATTTTGCTCTTCACTCTCCCCAGCCAATAAAGCGTCTGTGGC
GATTGGTGAACAGCATAAACAGCTGGACCTCAGCAAGGGTCAGGCAAACCCAGTCACTCGGAAGGCAGCTGTGTGAGCTGCCAAGCTAGT
GGGCTTCAGGTGCAAGGGTACCTGTGCCACACCAACCTGGGAGCACACAGAATACTATTAATGTGCACCCAGCTGGTCTCCCCAGGCAAG
AAGGTATCCTCTTCCCAAGGTGTACCCACTGAATGTTGTTACTACATATTGAGAGTCATTTTATGCATATGCATTCTACCTTTCCTGCTT
TATGAGTATTTTTAAGCTTTTAGTTCAAGGTTATATTCAGAAAATATTTCCCAGTATAATGATACATCGTAGCCTAAGAAATATTTTCTC
AATGTAATTCCCTTCCCAGCTACCCAAATGCTACAGAGAAATGTTTTCTACTTGGCCACTATCAGGGTTCGTCATCTATTGTGTTGACTA
TTAATGGCTTTTTGATTGGGTAAGGATTTTGCTATAGATGAAGGTAGAGGGCTGTCAGCCCTGAAAAACACACAGGTCAGACATTTAAAA
GGCATGGGTTTCGAGCTGTCTCAAAATATTGCCCAATAGCCATAATTTTACCAGCCTTTCTGTCATATGCTGCTATTACAAAGTGGAAGC
TGTTGAATGTTTATTGGTGCCCAGGGTTTTGCTCTCCAATCTAGGTTCAGTTGAAGGAATATTGTTTCTAAGACTGTTTTGAGACATGTC
CAGTACATCACAAAGGAGATCGGGGCGACCCCTGCAGATGTGGAGCCATTAGCCCAGTTGAGGATATTCTCCAAGTTGTCCTCTCTCCTG
CTGATGGAAATGGGAATGAAGTTAAGTGGTCTGAAAAACTTGAATCGTTCACATTTCTCAGCTCTGGGGGTCATTTACCAGTTTGTTGTA
GAAGAAATAATCAGGTAAGTTAAAAGTTCATTTCCAGAGAAGGTAAACCCCACTTACCATCTCTGCATGATTTCAGTGGGAATTGATTAT
CACTAATCCCCAACTGGGCTAGAATAAATGTAAAGTTTGACCTTTTTAAAACGAAAAGAGAGACAAAGTCTCAGCACATTCCAAGGAGTG
GTAGAAACAGAGCTGAAGGTGTCCCCATTGTAGATTAGTCTCTTCTCACTAAAATTTACTTTCCAACGTAGGGCCTAAAGGAAACCTTTC
TTAAAGACAGGCTGAAACCCCTTCAAAGGCAGATGAGGAGGTACAGACACGTGACCTTTTGGTGCACACTGGAGCTACTTGGACAAGACC
AGCATGCCTTGCTGCACGTGTGTGTATTTCACTGCTGAGAACATCCTTTAACTTGGTGTGCAATTTGAAAGGATGTGAATCATGGATGGA
AGGCCATTTGTACATGTCCCTTGGCAAAATTCTTTCTGGTGTCTCCTAACTTCAGAGACAGGGACTCTTTTTGGATCTCTATTGACAAGT
AATAAAAGTCTGGCCCTCATAACTTGTTTCCGAACTAGAAAAGTCTGTGAGACCCCTACATCATTCTGGTTTTTTTGCTTGAGTAAGAAC
AATCCTTTTTTATTTTTCTTCTGTACAGTCTAAAGCTACAGAGAAAAAAAAATGCACTCTTCCCTTGCCGGCTCCTGGTACCATTGGTCT
GAACAGCTGTAGTTGGTCTACTCCTTACTTAGCACTTGATTGTGTGGGGAAACAAAGGTGGGAGGGGTGGGGAATACTGGAAATAATCAG
GGCAATTTTTTTCTTTCCCATAATTGGACTAGATACCTTGGTACTGTTGACCTTCTCAGCATCTCCCTTTTGCCTTAGATGGCAACACCC
TCCAGTCTGTAGCAGAGCAGTCCAACCCAGATTAGTGCAGCCCGGAGGCTTAGGGTGCAGCCTCCCTGGTCTTCCTCCACACAGTTGTTC
ACCAACAGACCAGACCTCCTTTAACCACAGTGTCAACATAGTATCGGAAAGAGAGCCATTTCTTAGGGGAATAAAACAGTTTCGCTTCTT
TAGCTCATCTGTGGTGTCAGAATCCTTGGAGCTGAAGAGAGAAATCAAAAGAGCATGATGATGGCTGCCTGGTTTCAGGTGGAACTTAAT
GCATTGATCTTTAGAAGCTCCTTCTGTTGGAAGTTGAGTACCTGTGATCTAAAATGTCCTGGAGGCAGATGACATCTAAAATATGTGCTT
TCCAACCAGCACAGCTGGCGCTCTTAGCTCCTGATTGGTTGTGTGTTTTATTAAGGATCAGTGCAGTTAAGTCGTATTTTAAAGTGTTAC
CTCCCCTCCTAACCCTTCCCCTTCTTGGACACTGAAGGAAAAGGCCAACTAGGGTGTTAGCCCTCTGGGCACCAAGGAAACTAACAGCTT
TCTCAAAGCGGTGACCACTCAGGCCAGCCCAGACAAATCTGAGGGATGGCCAGTGCACTCCAATGATGGGACAGGCCTAACAACACATGT
AAGCTTCCCCGAGAGCTTTCAGCTGGTTCACCTCTTTGTTCTCTAGACTCTTAAGTACTGACTGCTTTGACTTTTGTGATTATGTTATGG
TGATGTGTAGTCAGTGTACCAATATGTTCACAACCTAGGATCATGATAATGGAGTGTGTTTTGGGTTTTTTTTAACTGTTCAGAAAAAAA

>51946_51946_4_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370318_BTRC_chr10_103281395_ENST00000370187_length(amino acids)=734AA_BP=237
MRPFPETDSSFGEQKAPAMQPWHGKAMQRASEAGATAPKASARNARGAPMDPTESPAAPEAALPKAGKFGPARKSGSRQKKSAPDTQERP
PVRATGARAKKAPQRAQDTQPSDATSAPGAEGLEPPAAREPALSRAGSCRQRGARCSTKPRPPPGPWDVPSPGLPVSAPILVRRDAAPGA
SKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYF
EQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIER
MVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLR
DNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMA
SPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRV
LEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAE

--------------------------------------------------------------
>51946_51946_5_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370318_BTRC_chr10_103281395_ENST00000393441_length(transcript)=6403nt_BP=735nt
AACAGCTGCTGCTGGCTCTTCCTCTTGCGGCCTTTTCCTGAAACGGATTCTTCTTTCGGGGAACAGAAAGCGCCAGCCATGCAGCCTTGG
CACGGAAAGGCCATGCAGAGAGCTTCCGAGGCCGGAGCCACTGCCCCCAAGGCTTCCGCACGGAATGCCAGGGGCGCCCCGATGGATCCC
ACCGAGTCTCCGGCTGCCCCCGAGGCCGCCCTGCCTAAGGCGGGAAAGTTCGGCCCCGCCAGGAAGTCGGGATCCCGGCAGAAAAAGAGC
GCCCCGGACACCCAGGAGAGGCCGCCCGTCCGCGCAACTGGGGCCCGCGCCAAAAAGGCCCCTCAGCGCGCCCAGGACACGCAGCCGTCT
GACGCCACCAGCGCCCCTGGGGCAGAGGGGCTGGAGCCTCCTGCGGCTCGGGAGCCGGCTCTTTCCAGGGCTGGTTCTTGCCGCCAGAGG
GGCGCGCGCTGCTCCACGAAGCCAAGACCTCCGCCCGGGCCCTGGGACGTGCCCAGCCCCGGCCTGCCGGTCTCGGCCCCCATTCTCGTA
CGGAGGGATGCGGCGCCTGGGGCCTCGAAGCTCCGGGCGGTTTTGGAGAAGTTGAAGCTCAGCCGCGATGATATCTCCACGGCGGCGGGG
ATGGTGAAAGGGGTTGTGGACCACCTGCTGCTCAGACTGAAGTGCGACTCCGCGTTCAGAGGCGTCGGGCTGCTGAACACCGGGAGCTAC
TATGAGCACGTGAAGACAAAACTTGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAACGGAAACTCTCAGCAAGCTATGAAAAGGAA
AAGGAACTGTGTGTCAAATACTTTGAGCAGTGGTCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATATCCCAAATGTGTCATTAC
CAACATGGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCTCTGCCAGCTCGGGGATTGGATCATATTGCT
GAGAACATTCTGTCATACCTGGATGCCAAATCACTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAGTGACCTCTGATGGCATG
CTGTGGAAGAAGCTTATCGAGAGAATGGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCAGAACGAAGAGGATGGGGACAGTATTTATTC
AAAAACAAACCTCCTGACGGGAATGCTCCTCCCAACTCTTTTTATAGAGCACTTTATCCTAAAATTATACAAGACATTGAGACAATAGAA
TCTAATTGGAGATGTGGAAGACATAGTTTACAGAGAATTCACTGCCGAAGTGAAACAAGCAAAGGAGTTTACTGTTTACAGTATGATGAT
CAGAAAATAGTAAGCGGCCTTCGAGACAACACAATCAAGATCTGGGATAAAAACACATTGGAATGCAAGCGAATTCTCACAGGCCATACA
GGTTCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCATCGGATTCCACGGTCAGAGTGTGGGATGTAAATACAGGT
GAAATGCTAAACACGTTGATTCACCATTGTGAAGCAGTTCTGCACTTGCGTTTCAATAATGGCATGATGGTGACCTGCTCCAAAGATCGT
TCCATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGGGTGCTGGTCGGACACCGAGCTGCTGTCAATGTTGTAGAC
TTTGATGACAAGTACATTGTTTCTGCATCTGGGGATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAATTTGTAAGGACCTTAAAT
GGACACAAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTGAGTGGCTCATCTGACAACACTATCAGATTATGGGACATA
GAATGTGGTGCATGTTTACGAGTGTTAGAAGGCCATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGAGGATAGTCAGTGGGGCC
TATGATGGAAAAATTAAAGTGTGGGATCTTGTGGCTGCTTTGGACCCCCGTGCTCCTGCAGGGACACTCTGTCTACGGACCCTTGTGGAG
CATTCCGGAAGAGTTTTTCGACTACAGTTTGATGAATTCCAGATTGTCAGTAGTTCACATGATGACACAATCCTCATCTGGGACTTCCTA
AATGATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCCTTCTCGAACATACACCTACATCTCCAGATAAATAACCATACACTGACCTCAT
ACTTGCCCAGGACCCATTAAAGTTGCGGTATTTAACGTATCTGCCAATACCAGGATGAGCAACAACAGTAACAATCAAACTACTGCCCAG
TTTCCCTGGACTAGCCGAGGAGCAGGGCTTTGAGACTCCTGTTGGGACACAGTTGGTCTGCAGTCGGCCCAGGACGGTCTACTCAGCACA
ACTGACTGCTTCAGTGCTGCTATCAGAAGATGTCTTCTATCTTTTGTGAATGATTGGAACTTTTAAACCTCCCCTCCTCTCCTCCTTTCA
CCTCTGCACCTAGTTTTTTCCCATTGGTTCCAGACAAAGGTGACTTATAAATATATTTAGTGTTTTGCCAGAATCTCTCTTGCTTTGCCA
TTAAGCAGAAGAACTAGTTTCCCTGTATAGCCTGCTGGGAGAGACCCACTTCTAGGGTATGGGGGATGCAGCTTCAAGCCCAGTGCCCAG
TGTCTCCCTGTTAACTGCAGGAATGCCAAGCACCTGGCCAGAGCAGCCCAGCCCCAATATGCTTAGGAGGAGACAGAGTTCCCTCTGTAT
AGCCTCTGGGACAAGAAAAAGAAAACACAAGAATGTATACACTGGAAGATTTGGGCCTCCTGCCTGCCTTCTCTTTGTTTCTGTTCCTCT
TCCCATCTACTCCCCTACGCCCCTTCAACCTTTTTTCTCTGTCTGCTTCACCTGAGAAGAAAGTGTACGAAGAGAGTGTCCTCCTCTCAC
ATGAGCCAGATCAGCCAGAAAATGCAACACTTGGAAGAGTTAAATGCTGTTCAGTGAAGATTTCAGCCCCAGGCCTTTGCTGCAAGTGAC
CCTGTGGCAACAGTGGATTCTCAGACATGATACTCTCATCATATTTGCAACTCTTCTCTCTCTTTCTTCCCCACACCCAAGAGGAGGATT
GGTGGTAGGGGGCAGGCAGAGGGGGTGGGGAGAAGTTTCCTGGGCTCCATCAATGGCTGCATCTTTTCTGGACTCAGCAGTCTCCTTGAT
TCCATGTAGAGTGTGGAAAGGAGTTGCTGATTGCATTTCCTCTCATTAACAATTGGGTGTGTAATAAAAAGCATTGTACTTCATCTTAAA
TCACTGGTAAGGCTCAGCCTACAGAAAGATTTGAAATGGCCAGAGCCAATCGCTTGGTGCATTCTGCGTAATGGTTTCCATCTCCGATTT
CCTCATCAGGGCCTGTGAATACCCAGGTGCCTGTATCTTTGCCAAGACCGTGATCAAGGTAGCTTAAGAGAGATGGTCAGGAGAAAACAC
TGTTTTTGTTTTTTTTGTTGTTTTGTTTTGTTTTGGCCAGTTAAATATCATCTCTCAAATATTGATCTCACCGTGTCAACCTTGCACTGC
ACAACCTTCCTTCTGCTTCTCCCACACCCAGTATTTGCAGAAGGGCAAAGCTGCTTAAGAGAGAGGATCAGGGTGAAGTTTGGCACACAG
GGTTTATTAATGGGGCAAAAACTGCCTTTTCTTCCTCCTCCTGACCTTATTTTGCTCTTCACTCTCCCCAGCCAATAAAGCGTCTGTGGC
GATTGGTGAACAGCATAAACAGCTGGACCTCAGCAAGGGTCAGGCAAACCCAGTCACTCGGAAGGCAGCTGTGTGAGCTGCCAAGCTAGT
GGGCTTCAGGTGCAAGGGTACCTGTGCCACACCAACCTGGGAGCACACAGAATACTATTAATGTGCACCCAGCTGGTCTCCCCAGGCAAG
AAGGTATCCTCTTCCCAAGGTGTACCCACTGAATGTTGTTACTACATATTGAGAGTCATTTTATGCATATGCATTCTACCTTTCCTGCTT
TATGAGTATTTTTAAGCTTTTAGTTCAAGGTTATATTCAGAAAATATTTCCCAGTATAATGATACATCGTAGCCTAAGAAATATTTTCTC
AATGTAATTCCCTTCCCAGCTACCCAAATGCTACAGAGAAATGTTTTCTACTTGGCCACTATCAGGGTTCGTCATCTATTGTGTTGACTA
TTAATGGCTTTTTGATTGGGTAAGGATTTTGCTATAGATGAAGGTAGAGGGCTGTCAGCCCTGAAAAACACACAGGTCAGACATTTAAAA
GGCATGGGTTTCGAGCTGTCTCAAAATATTGCCCAATAGCCATAATTTTACCAGCCTTTCTGTCATATGCTGCTATTACAAAGTGGAAGC
TGTTGAATGTTTATTGGTGCCCAGGGTTTTGCTCTCCAATCTAGGTTCAGTTGAAGGAATATTGTTTCTAAGACTGTTTTGAGACATGTC
CAGTACATCACAAAGGAGATCGGGGCGACCCCTGCAGATGTGGAGCCATTAGCCCAGTTGAGGATATTCTCCAAGTTGTCCTCTCTCCTG
CTGATGGAAATGGGAATGAAGTTAAGTGGTCTGAAAAACTTGAATCGTTCACATTTCTCAGCTCTGGGGGTCATTTACCAGTTTGTTGTA
GAAGAAATAATCAGGTAAGTTAAAAGTTCATTTCCAGAGAAGGTAAACCCCACTTACCATCTCTGCATGATTTCAGTGGGAATTGATTAT
CACTAATCCCCAACTGGGCTAGAATAAATGTAAAGTTTGACCTTTTTAAAACGAAAAGAGAGACAAAGTCTCAGCACATTCCAAGGAGTG
GTAGAAACAGAGCTGAAGGTGTCCCCATTGTAGATTAGTCTCTTCTCACTAAAATTTACTTTCCAACGTAGGGCCTAAAGGAAACCTTTC
TTAAAGACAGGCTGAAACCCCTTCAAAGGCAGATGAGGAGGTACAGACACGTGACCTTTTGGTGCACACTGGAGCTACTTGGACAAGACC
AGCATGCCTTGCTGCACGTGTGTGTATTTCACTGCTGAGAACATCCTTTAACTTGGTGTGCAATTTGAAAGGATGTGAATCATGGATGGA
AGGCCATTTGTACATGTCCCTTGGCAAAATTCTTTCTGGTGTCTCCTAACTTCAGAGACAGGGACTCTTTTTGGATCTCTATTGACAAGT
AATAAAAGTCTGGCCCTCATAACTTGTTTCCGAACTAGAAAAGTCTGTGAGACCCCTACATCATTCTGGTTTTTTTGCTTGAGTAAGAAC
AATCCTTTTTTATTTTTCTTCTGTACAGTCTAAAGCTACAGAGAAAAAAAAATGCACTCTTCCCTTGCCGGCTCCTGGTACCATTGGTCT
GAACAGCTGTAGTTGGTCTACTCCTTACTTAGCACTTGATTGTGTGGGGAAACAAAGGTGGGAGGGGTGGGGAATACTGGAAATAATCAG
GGCAATTTTTTTCTTTCCCATAATTGGACTAGATACCTTGGTACTGTTGACCTTCTCAGCATCTCCCTTTTGCCTTAGATGGCAACACCC
TCCAGTCTGTAGCAGAGCAGTCCAACCCAGATTAGTGCAGCCCGGAGGCTTAGGGTGCAGCCTCCCTGGTCTTCCTCCACACAGTTGTTC
ACCAACAGACCAGACCTCCTTTAACCACAGTGTCAACATAGTATCGGAAAGAGAGCCATTTCTTAGGGGAATAAAACAGTTTCGCTTCTT
TAGCTCATCTGTGGTGTCAGAATCCTTGGAGCTGAAGAGAGAAATCAAAAGAGCATGATGATGGCTGCCTGGTTTCAGGTGGAACTTAAT
GCATTGATCTTTAGAAGCTCCTTCTGTTGGAAGTTGAGTACCTGTGATCTAAAATGTCCTGGAGGCAGATGACATCTAAAATATGTGCTT
TCCAACCAGCACAGCTGGCGCTCTTAGCTCCTGATTGGTTGTGTGTTTTATTAAGGATCAGTGCAGTTAAGTCGTATTTTAAAGTGTTAC
CTCCCCTCCTAACCCTTCCCCTTCTTGGACACTGAAGGAAAAGGCCAACTAGGGTGTTAGCCCTCTGGGCACCAAGGAAACTAACAGCTT
TCTCAAAGCGGTGACCACTCAGGCCAGCCCAGACAAATCTGAGGGATGGCCAGTGCACTCCAATGATGGGACAGGCCTAACAACACATGT
AAGCTTCCCCGAGAGCTTTCAGCTGGTTCACCTCTTTGTTCTCTAGACTCTTAAGTACTGACTGCTTTGACTTTTGTGATTATGTTATGG
TGATGTGTAGTCAGTGTACCAATATGTTCACAACCTAGGATCATGATAATGGAGTGTGTTTTGGGTTTTTTTTAACTGTTCAGAAAAAAA

>51946_51946_5_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370318_BTRC_chr10_103281395_ENST00000393441_length(amino acids)=734AA_BP=237
MRPFPETDSSFGEQKAPAMQPWHGKAMQRASEAGATAPKASARNARGAPMDPTESPAAPEAALPKAGKFGPARKSGSRQKKSAPDTQERP
PVRATGARAKKAPQRAQDTQPSDATSAPGAEGLEPPAAREPALSRAGSCRQRGARCSTKPRPPPGPWDVPSPGLPVSAPILVRRDAAPGA
SKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYF
EQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIER
MVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLR
DNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMA
SPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRV
LEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAE

--------------------------------------------------------------
>51946_51946_6_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370318_BTRC_chr10_103281395_ENST00000408038_length(transcript)=6427nt_BP=735nt
AACAGCTGCTGCTGGCTCTTCCTCTTGCGGCCTTTTCCTGAAACGGATTCTTCTTTCGGGGAACAGAAAGCGCCAGCCATGCAGCCTTGG
CACGGAAAGGCCATGCAGAGAGCTTCCGAGGCCGGAGCCACTGCCCCCAAGGCTTCCGCACGGAATGCCAGGGGCGCCCCGATGGATCCC
ACCGAGTCTCCGGCTGCCCCCGAGGCCGCCCTGCCTAAGGCGGGAAAGTTCGGCCCCGCCAGGAAGTCGGGATCCCGGCAGAAAAAGAGC
GCCCCGGACACCCAGGAGAGGCCGCCCGTCCGCGCAACTGGGGCCCGCGCCAAAAAGGCCCCTCAGCGCGCCCAGGACACGCAGCCGTCT
GACGCCACCAGCGCCCCTGGGGCAGAGGGGCTGGAGCCTCCTGCGGCTCGGGAGCCGGCTCTTTCCAGGGCTGGTTCTTGCCGCCAGAGG
GGCGCGCGCTGCTCCACGAAGCCAAGACCTCCGCCCGGGCCCTGGGACGTGCCCAGCCCCGGCCTGCCGGTCTCGGCCCCCATTCTCGTA
CGGAGGGATGCGGCGCCTGGGGCCTCGAAGCTCCGGGCGGTTTTGGAGAAGTTGAAGCTCAGCCGCGATGATATCTCCACGGCGGCGGGG
ATGGTGAAAGGGGTTGTGGACCACCTGCTGCTCAGACTGAAGTGCGACTCCGCGTTCAGAGGCGTCGGGCTGCTGAACACCGGGAGCTAC
TATGAGCACGTGAAGACAAAACTTGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAACGGAAACTCTCAGCAAGCTATGAAAAGGAA
AAGGAACTGTGTGTCAAATACTTTGAGCAGTGGTCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATATCCCAAATGTGTCATTAC
CAACATGGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCTCTGCCAGCTCGGGGATTGGATCATATTGCT
GAGAACATTCTGTCATACCTGGATGCCAAATCACTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAGTGACCTCTGATGGCATG
CTGTGGAAGAAGCTTATCGAGAGAATGGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCAGAACGAAGAGGATGGGGACAGTATTTATTC
AAAAACAAACCTCCTGACGGGAATGCTCCTCCCAACTCTTTTTATAGAGCACTTTATCCTAAAATTATACAAGACATTGAGACAATAGAA
TCTAATTGGAGATGTGGAAGACATAGTTTACAGAGAATTCACTGCCGAAGTGAAACAAGCAAAGGAGTTTACTGTTTACAGTATGATGAT
CAGAAAATAGTAAGCGGCCTTCGAGACAACACAATCAAGATCTGGGATAAAAACACATTGGAATGCAAGCGAATTCTCACAGGCCATACA
GGTTCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCATCGGATTCCACGGTCAGAGTGTGGGATGTAAATACAGGT
GAAATGCTAAACACGTTGATTCACCATTGTGAAGCAGTTCTGCACTTGCGTTTCAATAATGGCATGATGGTGACCTGCTCCAAAGATCGT
TCCATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGGGTGCTGGTCGGACACCGAGCTGCTGTCAATGTTGTAGAC
TTTGATGACAAGTACATTGTTTCTGCATCTGGGGATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAATTTGTAAGGACCTTAAAT
GGACACAAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTGAGTGGCTCATCTGACAACACTATCAGATTATGGGACATA
GAATGTGGTGCATGTTTACGAGTGTTAGAAGGCCATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGAGGATAGTCAGTGGGGCC
TATGATGGAAAAATTAAAGTGTGGGATCTTGTGGCTGCTTTGGACCCCCGTGCTCCTGCAGGGACACTCTGTCTACGGACCCTTGTGGAG
CATTCCGGAAGAGTTTTTCGACTACAGTTTGATGAATTCCAGATTGTCAGTAGTTCACATGATGACACAATCCTCATCTGGGACTTCCTA
AATGATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCCTTCTCGAACATACACCTACATCTCCAGATAAATAACCATACACTGACCTCAT
ACTTGCCCAGGACCCATTAAAGTTGCGGTATTTAACGTATCTGCCAATACCAGGATGAGCAACAACAGTAACAATCAAACTACTGCCCAG
TTTCCCTGGACTAGCCGAGGAGCAGGGCTTTGAGACTCCTGTTGGGACACAGTTGGTCTGCAGTCGGCCCAGGACGGTCTACTCAGCACA
ACTGACTGCTTCAGTGCTGCTATCAGAAGATGTCTTCTATCTTTTGTGAATGATTGGAACTTTTAAACCTCCCCTCCTCTCCTCCTTTCA
CCTCTGCACCTAGTTTTTTCCCATTGGTTCCAGACAAAGGTGACTTATAAATATATTTAGTGTTTTGCCAGAATCTCTCTTGCTTTGCCA
TTAAGCAGAAGAACTAGTTTCCCTGTATAGCCTGCTGGGAGAGACCCACTTCTAGGGTATGGGGGATGCAGCTTCAAGCCCAGTGCCCAG
TGTCTCCCTGTTAACTGCAGGAATGCCAAGCACCTGGCCAGAGCAGCCCAGCCCCAATATGCTTAGGAGGAGACAGAGTTCCCTCTGTAT
AGCCTCTGGGACAAGAAAAAGAAAACACAAGAATGTATACACTGGAAGATTTGGGCCTCCTGCCTGCCTTCTCTTTGTTTCTGTTCCTCT
TCCCATCTACTCCCCTACGCCCCTTCAACCTTTTTTCTCTGTCTGCTTCACCTGAGAAGAAAGTGTACGAAGAGAGTGTCCTCCTCTCAC
ATGAGCCAGATCAGCCAGAAAATGCAACACTTGGAAGAGTTAAATGCTGTTCAGTGAAGATTTCAGCCCCAGGCCTTTGCTGCAAGTGAC
CCTGTGGCAACAGTGGATTCTCAGACATGATACTCTCATCATATTTGCAACTCTTCTCTCTCTTTCTTCCCCACACCCAAGAGGAGGATT
GGTGGTAGGGGGCAGGCAGAGGGGGTGGGGAGAAGTTTCCTGGGCTCCATCAATGGCTGCATCTTTTCTGGACTCAGCAGTCTCCTTGAT
TCCATGTAGAGTGTGGAAAGGAGTTGCTGATTGCATTTCCTCTCATTAACAATTGGGTGTGTAATAAAAAGCATTGTACTTCATCTTAAA
TCACTGGTAAGGCTCAGCCTACAGAAAGATTTGAAATGGCCAGAGCCAATCGCTTGGTGCATTCTGCGTAATGGTTTCCATCTCCGATTT
CCTCATCAGGGCCTGTGAATACCCAGGTGCCTGTATCTTTGCCAAGACCGTGATCAAGGTAGCTTAAGAGAGATGGTCAGGAGAAAACAC
TGTTTTTGTTTTTTTTGTTGTTTTGTTTTGTTTTGGCCAGTTAAATATCATCTCTCAAATATTGATCTCACCGTGTCAACCTTGCACTGC
ACAACCTTCCTTCTGCTTCTCCCACACCCAGTATTTGCAGAAGGGCAAAGCTGCTTAAGAGAGAGGATCAGGGTGAAGTTTGGCACACAG
GGTTTATTAATGGGGCAAAAACTGCCTTTTCTTCCTCCTCCTGACCTTATTTTGCTCTTCACTCTCCCCAGCCAATAAAGCGTCTGTGGC
GATTGGTGAACAGCATAAACAGCTGGACCTCAGCAAGGGTCAGGCAAACCCAGTCACTCGGAAGGCAGCTGTGTGAGCTGCCAAGCTAGT
GGGCTTCAGGTGCAAGGGTACCTGTGCCACACCAACCTGGGAGCACACAGAATACTATTAATGTGCACCCAGCTGGTCTCCCCAGGCAAG
AAGGTATCCTCTTCCCAAGGTGTACCCACTGAATGTTGTTACTACATATTGAGAGTCATTTTATGCATATGCATTCTACCTTTCCTGCTT
TATGAGTATTTTTAAGCTTTTAGTTCAAGGTTATATTCAGAAAATATTTCCCAGTATAATGATACATCGTAGCCTAAGAAATATTTTCTC
AATGTAATTCCCTTCCCAGCTACCCAAATGCTACAGAGAAATGTTTTCTACTTGGCCACTATCAGGGTTCGTCATCTATTGTGTTGACTA
TTAATGGCTTTTTGATTGGGTAAGGATTTTGCTATAGATGAAGGTAGAGGGCTGTCAGCCCTGAAAAACACACAGGTCAGACATTTAAAA
GGCATGGGTTTCGAGCTGTCTCAAAATATTGCCCAATAGCCATAATTTTACCAGCCTTTCTGTCATATGCTGCTATTACAAAGTGGAAGC
TGTTGAATGTTTATTGGTGCCCAGGGTTTTGCTCTCCAATCTAGGTTCAGTTGAAGGAATATTGTTTCTAAGACTGTTTTGAGACATGTC
CAGTACATCACAAAGGAGATCGGGGCGACCCCTGCAGATGTGGAGCCATTAGCCCAGTTGAGGATATTCTCCAAGTTGTCCTCTCTCCTG
CTGATGGAAATGGGAATGAAGTTAAGTGGTCTGAAAAACTTGAATCGTTCACATTTCTCAGCTCTGGGGGTCATTTACCAGTTTGTTGTA
GAAGAAATAATCAGGTAAGTTAAAAGTTCATTTCCAGAGAAGGTAAACCCCACTTACCATCTCTGCATGATTTCAGTGGGAATTGATTAT
CACTAATCCCCAACTGGGCTAGAATAAATGTAAAGTTTGACCTTTTTAAAACGAAAAGAGAGACAAAGTCTCAGCACATTCCAAGGAGTG
GTAGAAACAGAGCTGAAGGTGTCCCCATTGTAGATTAGTCTCTTCTCACTAAAATTTACTTTCCAACGTAGGGCCTAAAGGAAACCTTTC
TTAAAGACAGGCTGAAACCCCTTCAAAGGCAGATGAGGAGGTACAGACACGTGACCTTTTGGTGCACACTGGAGCTACTTGGACAAGACC
AGCATGCCTTGCTGCACGTGTGTGTATTTCACTGCTGAGAACATCCTTTAACTTGGTGTGCAATTTGAAAGGATGTGAATCATGGATGGA
AGGCCATTTGTACATGTCCCTTGGCAAAATTCTTTCTGGTGTCTCCTAACTTCAGAGACAGGGACTCTTTTTGGATCTCTATTGACAAGT
AATAAAAGTCTGGCCCTCATAACTTGTTTCCGAACTAGAAAAGTCTGTGAGACCCCTACATCATTCTGGTTTTTTTGCTTGAGTAAGAAC
AATCCTTTTTTATTTTTCTTCTGTACAGTCTAAAGCTACAGAGAAAAAAAAATGCACTCTTCCCTTGCCGGCTCCTGGTACCATTGGTCT
GAACAGCTGTAGTTGGTCTACTCCTTACTTAGCACTTGATTGTGTGGGGAAACAAAGGTGGGAGGGGTGGGGAATACTGGAAATAATCAG
GGCAATTTTTTTCTTTCCCATAATTGGACTAGATACCTTGGTACTGTTGACCTTCTCAGCATCTCCCTTTTGCCTTAGATGGCAACACCC
TCCAGTCTGTAGCAGAGCAGTCCAACCCAGATTAGTGCAGCCCGGAGGCTTAGGGTGCAGCCTCCCTGGTCTTCCTCCACACAGTTGTTC
ACCAACAGACCAGACCTCCTTTAACCACAGTGTCAACATAGTATCGGAAAGAGAGCCATTTCTTAGGGGAATAAAACAGTTTCGCTTCTT
TAGCTCATCTGTGGTGTCAGAATCCTTGGAGCTGAAGAGAGAAATCAAAAGAGCATGATGATGGCTGCCTGGTTTCAGGTGGAACTTAAT
GCATTGATCTTTAGAAGCTCCTTCTGTTGGAAGTTGAGTACCTGTGATCTAAAATGTCCTGGAGGCAGATGACATCTAAAATATGTGCTT
TCCAACCAGCACAGCTGGCGCTCTTAGCTCCTGATTGGTTGTGTGTTTTATTAAGGATCAGTGCAGTTAAGTCGTATTTTAAAGTGTTAC
CTCCCCTCCTAACCCTTCCCCTTCTTGGACACTGAAGGAAAAGGCCAACTAGGGTGTTAGCCCTCTGGGCACCAAGGAAACTAACAGCTT
TCTCAAAGCGGTGACCACTCAGGCCAGCCCAGACAAATCTGAGGGATGGCCAGTGCACTCCAATGATGGGACAGGCCTAACAACACATGT
AAGCTTCCCCGAGAGCTTTCAGCTGGTTCACCTCTTTGTTCTCTAGACTCTTAAGTACTGACTGCTTTGACTTTTGTGATTATGTTATGG
TGATGTGTAGTCAGTGTACCAATATGTTCACAACCTAGGATCATGATAATGGAGTGTGTTTTGGGTTTTTTTTAACTGTTCAGAAAAAAA

>51946_51946_6_MB21D1-BTRC_MB21D1_chr6_74161247_ENST00000370318_BTRC_chr10_103281395_ENST00000408038_length(amino acids)=734AA_BP=237
MRPFPETDSSFGEQKAPAMQPWHGKAMQRASEAGATAPKASARNARGAPMDPTESPAAPEAALPKAGKFGPARKSGSRQKKSAPDTQERP
PVRATGARAKKAPQRAQDTQPSDATSAPGAEGLEPPAAREPALSRAGSCRQRGARCSTKPRPPPGPWDVPSPGLPVSAPILVRRDAAPGA
SKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYF
EQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIER
MVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLR
DNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMA
SPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRV
LEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAE

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Fusion Gene PPI Analysis for MB21D1-BTRC


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MB21D1-BTRC


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MB21D1-BTRC


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource