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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MBNL1-RPIA (FusionGDB2 ID:52012)

Fusion Gene Summary for MBNL1-RPIA

check button Fusion gene summary
Fusion gene informationFusion gene name: MBNL1-RPIA
Fusion gene ID: 52012
HgeneTgene
Gene symbol

MBNL1

RPIA

Gene ID

4154

22934

Gene namemuscleblind like splicing regulator 1ribose 5-phosphate isomerase A
SynonymsEXP|MBNLRPI|RPIAD
Cytomap

3q25.1-q25.2

2p11.2

Type of geneprotein-codingprotein-coding
Descriptionmuscleblind-like protein 1muscleblind-liketriplet-expansion RNA-binding proteinribose-5-phosphate isomerasephosphoriboisomeraseribose 5-phosphate epimerase
Modification date2020032720200327
UniProtAcc

Q9NR56

.
Ensembl transtripts involved in fusion geneENST00000282486, ENST00000282488, 
ENST00000324210, ENST00000355460, 
ENST00000357472, ENST00000463374, 
ENST00000485910, ENST00000492948, 
ENST00000493459, ENST00000498502, 
ENST00000545754, ENST00000324196, 
ENST00000461436, ENST00000485509, 
ENST00000283646, 
Fusion gene scores* DoF score19 X 10 X 10=19004 X 3 X 3=36
# samples 214
** MAII scorelog2(21/1900*10)=-3.17753818555219
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: MBNL1 [Title/Abstract] AND RPIA [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMBNL1(152165562)-RPIA(89049498), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMBNL1

GO:0008380

RNA splicing

18335541

HgeneMBNL1

GO:0043484

regulation of RNA splicing

15257297|16946708


check buttonFusion gene breakpoints across MBNL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RPIA (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8366-01AMBNL1chr3

152165562

+RPIAchr2

89049498

+


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Fusion Gene ORF analysis for MBNL1-RPIA

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000282486ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
In-frameENST00000282488ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
In-frameENST00000324210ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
In-frameENST00000355460ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
In-frameENST00000357472ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
In-frameENST00000463374ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
In-frameENST00000485910ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
In-frameENST00000492948ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
In-frameENST00000493459ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
In-frameENST00000498502ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
In-frameENST00000545754ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
intron-3CDSENST00000324196ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
intron-3CDSENST00000461436ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+
intron-3CDSENST00000485509ENST00000283646MBNL1chr3

152165562

+RPIAchr2

89049498

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000282488MBNL1chr3152165562+ENST00000283646RPIAchr289049498+3554259918422696284
ENST00000282486MBNL1chr3152165562+ENST00000283646RPIAchr289049498+3812285718422954370
ENST00000355460MBNL1chr3152165562+ENST00000283646RPIAchr289049498+3330237514142472352
ENST00000493459MBNL1chr3152165562+ENST00000283646RPIAchr289049498+212011653211262313
ENST00000324210MBNL1chr3152165562+ENST00000283646RPIAchr289049498+283518809191977352
ENST00000498502MBNL1chr3152165562+ENST00000283646RPIAchr289049498+275918047891901370
ENST00000545754MBNL1chr3152165562+ENST00000283646RPIAchr289049498+250115467891643284
ENST00000357472MBNL1chr3152165562+ENST00000283646RPIAchr289049498+270517507891847352
ENST00000485910MBNL1chr3152165562+ENST00000283646RPIAchr289049498+222312685111365284
ENST00000463374MBNL1chr3152165562+ENST00000283646RPIAchr289049498+248115265111623370
ENST00000492948MBNL1chr3152165562+ENST00000283646RPIAchr289049498+191696101058352

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000282488ENST00000283646MBNL1chr3152165562+RPIAchr289049498+0.0007287640.9992712
ENST00000282486ENST00000283646MBNL1chr3152165562+RPIAchr289049498+0.000530970.9994691
ENST00000355460ENST00000283646MBNL1chr3152165562+RPIAchr289049498+0.0004716520.9995284
ENST00000493459ENST00000283646MBNL1chr3152165562+RPIAchr289049498+0.001374880.99862516
ENST00000324210ENST00000283646MBNL1chr3152165562+RPIAchr289049498+0.000316190.99968386
ENST00000498502ENST00000283646MBNL1chr3152165562+RPIAchr289049498+0.000495920.9995041
ENST00000545754ENST00000283646MBNL1chr3152165562+RPIAchr289049498+0.000795760.9992042
ENST00000357472ENST00000283646MBNL1chr3152165562+RPIAchr289049498+0.0003419320.9996581
ENST00000485910ENST00000283646MBNL1chr3152165562+RPIAchr289049498+0.0006509280.99934906
ENST00000463374ENST00000283646MBNL1chr3152165562+RPIAchr289049498+0.0004236680.9995764
ENST00000492948ENST00000283646MBNL1chr3152165562+RPIAchr289049498+0.0002979030.99970204

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Fusion Genomic Features for MBNL1-RPIA


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MBNL1-RPIA


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:152165562/chr2:89049498)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MBNL1

Q9NR56

.
FUNCTION: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. Regulates the TNNT2 exon 5 skipping through competition with U2AF2. Inhibits the formation of the spliceosome A complex on intron 4 of TNNT2 pre-mRNA. Binds to the stem-loop structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Binds to the 5'-YGCU(U/G)Y-3'consensus sequence. Binds to the IR RNA. Binds to expanded CUG repeat RNA, which folds into a hairpin structure containing GC base pairs and bulged, unpaired U residues. {ECO:0000269|PubMed:10970838, ECO:0000269|PubMed:15257297, ECO:0000269|PubMed:16946708, ECO:0000269|PubMed:18335541, ECO:0000269|PubMed:19470458}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMBNL1chr3:152165562chr2:89049498ENST00000282486+71013_413381169.6666666666667Zinc fingerC3H1-type 1
HgeneMBNL1chr3:152165562chr2:89049498ENST00000282486+710179_2073381169.6666666666667Zinc fingerC3H1-type 3
HgeneMBNL1chr3:152165562chr2:89049498ENST00000282486+710215_2413381169.6666666666667Zinc fingerC3H1-type 4
HgeneMBNL1chr3:152165562chr2:89049498ENST00000282486+71047_733381169.6666666666667Zinc fingerC3H1-type 2
HgeneMBNL1chr3:152165562chr2:89049498ENST00000282488+5813_412521083.6666666666667Zinc fingerC3H1-type 1
HgeneMBNL1chr3:152165562chr2:89049498ENST00000282488+58179_2072521083.6666666666667Zinc fingerC3H1-type 3
HgeneMBNL1chr3:152165562chr2:89049498ENST00000282488+58215_2412521083.6666666666667Zinc fingerC3H1-type 4
HgeneMBNL1chr3:152165562chr2:89049498ENST00000282488+5847_732521083.6666666666667Zinc fingerC3H1-type 2
HgeneMBNL1chr3:152165562chr2:89049498ENST00000324210+61013_413201466.0Zinc fingerC3H1-type 1
HgeneMBNL1chr3:152165562chr2:89049498ENST00000324210+610179_2073201466.0Zinc fingerC3H1-type 3
HgeneMBNL1chr3:152165562chr2:89049498ENST00000324210+610215_2413201466.0Zinc fingerC3H1-type 4
HgeneMBNL1chr3:152165562chr2:89049498ENST00000324210+61047_733201466.0Zinc fingerC3H1-type 2
HgeneMBNL1chr3:152165562chr2:89049498ENST00000355460+6913_413201294.6666666666667Zinc fingerC3H1-type 1
HgeneMBNL1chr3:152165562chr2:89049498ENST00000355460+69179_2073201294.6666666666667Zinc fingerC3H1-type 3
HgeneMBNL1chr3:152165562chr2:89049498ENST00000355460+69215_2413201294.6666666666667Zinc fingerC3H1-type 4
HgeneMBNL1chr3:152165562chr2:89049498ENST00000355460+6947_733201294.6666666666667Zinc fingerC3H1-type 2
HgeneMBNL1chr3:152165562chr2:89049498ENST00000357472+5813_413201153.6666666666667Zinc fingerC3H1-type 1
HgeneMBNL1chr3:152165562chr2:89049498ENST00000357472+58179_2073201153.6666666666667Zinc fingerC3H1-type 3
HgeneMBNL1chr3:152165562chr2:89049498ENST00000357472+58215_2413201153.6666666666667Zinc fingerC3H1-type 4
HgeneMBNL1chr3:152165562chr2:89049498ENST00000357472+5847_733201153.6666666666667Zinc fingerC3H1-type 2
HgeneMBNL1chr3:152165562chr2:89049498ENST00000463374+6913_413381292.6666666666667Zinc fingerC3H1-type 1
HgeneMBNL1chr3:152165562chr2:89049498ENST00000463374+69179_2073381292.6666666666667Zinc fingerC3H1-type 3
HgeneMBNL1chr3:152165562chr2:89049498ENST00000463374+69215_2413381292.6666666666667Zinc fingerC3H1-type 4
HgeneMBNL1chr3:152165562chr2:89049498ENST00000463374+6947_733381292.6666666666667Zinc fingerC3H1-type 2
HgeneMBNL1chr3:152165562chr2:89049498ENST00000485910+4713_412521014.3333333333334Zinc fingerC3H1-type 1
HgeneMBNL1chr3:152165562chr2:89049498ENST00000485910+47179_2072521014.3333333333334Zinc fingerC3H1-type 3
HgeneMBNL1chr3:152165562chr2:89049498ENST00000485910+47215_2412521014.3333333333334Zinc fingerC3H1-type 4
HgeneMBNL1chr3:152165562chr2:89049498ENST00000485910+4747_732521014.3333333333334Zinc fingerC3H1-type 2
HgeneMBNL1chr3:152165562chr2:89049498ENST00000492948+5713_41320343.0Zinc fingerC3H1-type 1
HgeneMBNL1chr3:152165562chr2:89049498ENST00000492948+57179_207320343.0Zinc fingerC3H1-type 3
HgeneMBNL1chr3:152165562chr2:89049498ENST00000492948+57215_241320343.0Zinc fingerC3H1-type 4
HgeneMBNL1chr3:152165562chr2:89049498ENST00000492948+5747_73320343.0Zinc fingerC3H1-type 2
HgeneMBNL1chr3:152165562chr2:89049498ENST00000545754+4813_412521125.6666666666667Zinc fingerC3H1-type 1
HgeneMBNL1chr3:152165562chr2:89049498ENST00000545754+48179_2072521125.6666666666667Zinc fingerC3H1-type 3
HgeneMBNL1chr3:152165562chr2:89049498ENST00000545754+48215_2412521125.6666666666667Zinc fingerC3H1-type 4
HgeneMBNL1chr3:152165562chr2:89049498ENST00000545754+4847_732521125.6666666666667Zinc fingerC3H1-type 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMBNL1chr3:152165562chr2:89049498ENST00000324196+1813_4101151.6666666666667Zinc fingerC3H1-type 1
HgeneMBNL1chr3:152165562chr2:89049498ENST00000324196+18179_20701151.6666666666667Zinc fingerC3H1-type 3
HgeneMBNL1chr3:152165562chr2:89049498ENST00000324196+18215_24101151.6666666666667Zinc fingerC3H1-type 4
HgeneMBNL1chr3:152165562chr2:89049498ENST00000324196+1847_7301151.6666666666667Zinc fingerC3H1-type 2
HgeneMBNL1chr3:152165562chr2:89049498ENST00000485509+1713_410341.0Zinc fingerC3H1-type 1
HgeneMBNL1chr3:152165562chr2:89049498ENST00000485509+17179_2070341.0Zinc fingerC3H1-type 3
HgeneMBNL1chr3:152165562chr2:89049498ENST00000485509+17215_2410341.0Zinc fingerC3H1-type 4
HgeneMBNL1chr3:152165562chr2:89049498ENST00000485509+1747_730341.0Zinc fingerC3H1-type 2


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Fusion Gene Sequence for MBNL1-RPIA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>52012_52012_1_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000282486_RPIA_chr2_89049498_ENST00000283646_length(transcript)=3812nt_BP=2857nt
TTACATCTTATAGCACCCAGTGAATTATGATATGGGGCTGCGGTTTATTTGCTCTGGCGACAATATGGCTTACTTGCCGTGGAATATCCC
GGTATTTCAGAAGTAACATATTATTTTTAAAGAGGGAGCTTTGCTTTCTCTAAATCACATGGTGCAAAGTTGGGAATACAGTGGCCTGTA
AATTACAAATATTATTTACAAACTAGAAGGAAAGCTGACATGTGTTTGTGCCTGTGTGACAGTTTCACTAAGGAATTCCAAAACTGTGGA
TAGCCTGTTACTTGAGAAAAATACACGGTGGCAGTCTTGCAGATGTTTTTCCCGCCTGTTAGCCCTCCAGGTTCAAAAACTGTTTGGTGC
ATTTTAAGGCGGCAGTCTCACCAGATCGCAGGATTCTAGTCTAATTGGCTTCTAACCTTCAATCTAACCTTGCCGGCTTCCTTGCAAAGC
CCGGTGCAAGGGCCTCTTTCAAAATGAACCCACTGGTGTGCCTAGCAGTCGGTAGAAGAAGCGGGAGGGCGTCCGGTCTGCACGCCCGCC
GCGAGGTTACAATGCTGAACGCATGAGATGGAAGATACCAACGGGAGGCCGAGGGGATCCACGGCGCCCGCGCGGGCTCCGGCTTCCTCC
TGCTCTCGGCGCCGCTGGGCGACCGCCCATGACCCGCTCTTGCGGGCTCTGTCCGGTTGACAGGCGACCCTGTGGCCCGGGGAAGCGCGG
GAGGGCGCCGGCGGAAAGTTGAAGAGCGTTTTTCTCGCCGCCGCGTGCATTAGGAGCTCGACGAGTCCGCCCTGGGCTTCCTGGTGGGGC
TGGGCGGGCGGGGGAGGGGCCGCGCAGCAGCAGCGGAAGCCAGACCTCGGCGATAAGAGGCTGCACAGCGACATGCAACAGTCTTTTCAC
TGCAGCTGAATGAGTTGTGGCGCCCACAATGCTCCCATGACAAGGAGCTGACAAGTTCCATTTTCCGTCGCGGGCATCTTGGAATCATGA
CTCCCACAATGCCTTGGGCACTTGGTCGACAGTGGGGCCGCCTCTGAAAAAAAAATGTGAGAGGTTGGTACTAAGAAGTGCCTTTCCTGA
CGTCTCTGCTGCTTGGAACCGCTTCTAGAGCAGTCTCTGCTTTTGCCTTGCTTGCTGCCAGCTAGACTGTGACGACAGCACATCCACCCT
CCACCTCTAGCCCAGACACCCCCATTTCTACTTATAATCAAGAGAAAAGCTCTAAGTATCTGGCATTGCCCTAGGCTGCTTTAGTGTTAA
AAGAAAAGTTTGCTGAAAAAGTAAGATATCTTCTGCCAGGAAATCAAGGAGGAAAAAAAAAATCATTTTCTCGATTTTGCTCTAAACTGC
TGCATCTGTCTATGCCAAACTAATCAATACCGATTGCACCACCAAACTCCATTGCAAATTCAGCTGTGAGGAGATTCCCTTTCAGACAAC
TTTGCTGAAAGCAGCTTGGAAATTCGGTGTCGAAGGGTCTGCCACGTTTTCATGCTTGCATTTTGGGCTCCAAATTGGCACTGGGAAGGG
GTTACTGAGAGCACAAGGCTGATACCAGGCCCTACTTTTAAACGTTCATCTACTTACAATCCTAGTATTTCTCTAAAAACCAAAACCTCT
TTGAATTAACAGTTTCATGCTGTGAATTTCTAGTGGGAGATCTTTTCCTTGATATTGACGACACAATTTTCCATGTACTTTTAAAGCAGG
GAGTGGGGAAAAGTATTTTGAGGGGACATTTTCATCATCAGTTCAGCTTTTTTTTTTTGGTTGTTGCTCTTTTTTGGGGGGGTTGGGTTT
GTTGGTTTCACTGAAACATTTAACTACCTGTAAAATCTAAACATGGCTGTTAGTGTCACACCAATTCGGGACACAAAATGGCTAACACTG
GAAGTATGTAGAGAGTTCCAGAGGGGGACTTGCTCACGGCCAGACACGGAATGTAAATTTGCACATCCTTCGAAAAGCTGCCAAGTTGAA
AATGGACGAGTAATCGCCTGCTTTGATTCATTGAAAGGCCGTTGCTCCAGGGAGAACTGCAAATATCTTCATCCACCCCCACATTTAAAA
ACGCAGTTGGAGATAAATGGACGCAATAACTTGATTCAGCAGAAGAACATGGCCATGTTGGCCCAGCAAATGCAACTAGCCAATGCCATG
ATGCCTGGTGCCCCATTACAACCCGTGCCAATGTTTTCAGTTGCACCAAGCTTAGCCACCAATGCATCAGCAGCCGCCTTTAATCCCTAT
CTGGGACCTGTTTCTCCAAGCCTGGTCCCGGCAGAGATCTTGCCGACTGCACCAATGTTGGTTACAGGGAATCCGGGTGTCCCTGTACCT
GCAGCTGCTGCAGCTGCTGCACAGAAATTAATGCGAACAGACAGACTTGAGGTATGTCGAGAGTACCAACGTGGCAATTGCAACCGAGGA
GAAAATGATTGTCGGTTTGCTCATCCTGCTGACAGCACAATGATTGACACCAATGACAACACAGTCACTGTGTGTATGGATTACATCAAA
GGGAGATGCTCTCGGGAAAAGTGCAAATACTTTCATCCCCCTGCACATTTGCAAGCCAAGATCAAGGCTGCCCAATACCAGGTCAACCAG
GCTGCAGCTGCACAGGCTGCAGCCACCGCAGCTGCCATGACTCAGTCGGCTGTCAAATCACTGAAGCGACCCCTCGAGGCAACCTTTGAC
CTGGGAATTCCTCAAGCTGTACTTCCCCCATTACCAAAGAGGCCTGCTCTTGAAAAAACCAACGGTGCCACCGCAGTCTTTAACACTGGT
ATTTTCCAATACCAACAGGCTCTAGCCAACATGCAGTTACAACAGCATACAGCATTTCTCCCACCAGGTGTGGTGGACACAGGCCTATTC
ATCAACATGGCTGAGAGAGTCTACTTTGGGATGCAGGATGGCTCAGTGAACATGAGGGAGAAGCCTTTCTGTTGACCCTGCAAGGAGCAG
AGTGTGTTCACCTTGAGTCTCCAGCCCACAGCCAAGGTGGACGTACCTCTCCAGGAGCCTTTGCCTTAATGTATCTCTGCCTGGACAACT
TGTGGTGGGGGGTGGGGGGAAGAGTGGGAGGGGGAGTTAAATCCAGTCTTATGAAGTATTGTTATTAAATGTCTTTTTAAAAAGAGAAAT
ATAAACATATATTTTTACTATTAAAATATTCAGTTTTTTAAATGAAGTAGAACTTGAGTTCATGTTTTATATGAAATATTTACCAAAAAA
AAAAAATGAGGTAAACTGTATTTAAAACCTTTGACTTGAGTCTGCTGGTAAAGCTTCTGAATATTGAGTTTGCTGAGAAATAAAAATCAA
AACTTCTTTAAGCTGGTAAAGTGAGGGGCCCACCAGCAGTGATCTCCTGATGCCTTACTGGAAACTTTGTTTACTTGTCTGCTACCCTCT
GATTTGTTTTTAGTTAGTTTTTATTGTGAGCACACATAGTACCTAGTTACATCTTAAGATCAGGTTTATAAAACTGTGGAGTGGAGCGGT
ATGGTATGGAATGACTTGGAATGTAAGCTGTCAGGGAGAAAATGTTGTTACACTTTTGCTAAGATCTGGGGGTTTCTTCATATTCCTGCT
GTTGGAAGCAGTTGACCAGAAATGCTTGCCAGTACTGCCAAAGCACTGCTGTGAAATGTGAAGTACTTTGTTTTTTTATTTTTAATGATT
TTCTTTTTGTTATTAATATTTTTCTCTGTTCCTTTGTTATTACTTGCATGGTTTGGCGTCAGAAGTCCTTACCTCTTTATATTGTTTGCA

>52012_52012_1_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000282486_RPIA_chr2_89049498_ENST00000283646_length(amino acids)=370AA_BP=336
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQ
KNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTD
RLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMT
QSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGVVDTGLFINMAERVYFGMQDG

--------------------------------------------------------------
>52012_52012_2_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000282488_RPIA_chr2_89049498_ENST00000283646_length(transcript)=3554nt_BP=2599nt
TTACATCTTATAGCACCCAGTGAATTATGATATGGGGCTGCGGTTTATTTGCTCTGGCGACAATATGGCTTACTTGCCGTGGAATATCCC
GGTATTTCAGAAGTAACATATTATTTTTAAAGAGGGAGCTTTGCTTTCTCTAAATCACATGGTGCAAAGTTGGGAATACAGTGGCCTGTA
AATTACAAATATTATTTACAAACTAGAAGGAAAGCTGACATGTGTTTGTGCCTGTGTGACAGTTTCACTAAGGAATTCCAAAACTGTGGA
TAGCCTGTTACTTGAGAAAAATACACGGTGGCAGTCTTGCAGATGTTTTTCCCGCCTGTTAGCCCTCCAGGTTCAAAAACTGTTTGGTGC
ATTTTAAGGCGGCAGTCTCACCAGATCGCAGGATTCTAGTCTAATTGGCTTCTAACCTTCAATCTAACCTTGCCGGCTTCCTTGCAAAGC
CCGGTGCAAGGGCCTCTTTCAAAATGAACCCACTGGTGTGCCTAGCAGTCGGTAGAAGAAGCGGGAGGGCGTCCGGTCTGCACGCCCGCC
GCGAGGTTACAATGCTGAACGCATGAGATGGAAGATACCAACGGGAGGCCGAGGGGATCCACGGCGCCCGCGCGGGCTCCGGCTTCCTCC
TGCTCTCGGCGCCGCTGGGCGACCGCCCATGACCCGCTCTTGCGGGCTCTGTCCGGTTGACAGGCGACCCTGTGGCCCGGGGAAGCGCGG
GAGGGCGCCGGCGGAAAGTTGAAGAGCGTTTTTCTCGCCGCCGCGTGCATTAGGAGCTCGACGAGTCCGCCCTGGGCTTCCTGGTGGGGC
TGGGCGGGCGGGGGAGGGGCCGCGCAGCAGCAGCGGAAGCCAGACCTCGGCGATAAGAGGCTGCACAGCGACATGCAACAGTCTTTTCAC
TGCAGCTGAATGAGTTGTGGCGCCCACAATGCTCCCATGACAAGGAGCTGACAAGTTCCATTTTCCGTCGCGGGCATCTTGGAATCATGA
CTCCCACAATGCCTTGGGCACTTGGTCGACAGTGGGGCCGCCTCTGAAAAAAAAATGTGAGAGGTTGGTACTAAGAAGTGCCTTTCCTGA
CGTCTCTGCTGCTTGGAACCGCTTCTAGAGCAGTCTCTGCTTTTGCCTTGCTTGCTGCCAGCTAGACTGTGACGACAGCACATCCACCCT
CCACCTCTAGCCCAGACACCCCCATTTCTACTTATAATCAAGAGAAAAGCTCTAAGTATCTGGCATTGCCCTAGGCTGCTTTAGTGTTAA
AAGAAAAGTTTGCTGAAAAAGTAAGATATCTTCTGCCAGGAAATCAAGGAGGAAAAAAAAAATCATTTTCTCGATTTTGCTCTAAACTGC
TGCATCTGTCTATGCCAAACTAATCAATACCGATTGCACCACCAAACTCCATTGCAAATTCAGCTGTGAGGAGATTCCCTTTCAGACAAC
TTTGCTGAAAGCAGCTTGGAAATTCGGTGTCGAAGGGTCTGCCACGTTTTCATGCTTGCATTTTGGGCTCCAAATTGGCACTGGGAAGGG
GTTACTGAGAGCACAAGGCTGATACCAGGCCCTACTTTTAAACGTTCATCTACTTACAATCCTAGTATTTCTCTAAAAACCAAAACCTCT
TTGAATTAACAGTTTCATGCTGTGAATTTCTAGTGGGAGATCTTTTCCTTGATATTGACGACACAATTTTCCATGTACTTTTAAAGCAGG
GAGTGGGGAAAAGTATTTTGAGGGGACATTTTCATCATCAGTTCAGCTTTTTTTTTTTGGTTGTTGCTCTTTTTTGGGGGGGTTGGGTTT
GTTGGTTTCACTGAAACATTTAACTACCTGTAAAATCTAAACATGGCTGTTAGTGTCACACCAATTCGGGACACAAAATGGCTAACACTG
GAAGTATGTAGAGAGTTCCAGAGGGGGACTTGCTCACGGCCAGACACGGAATGTAAATTTGCACATCCTTCGAAAAGCTGCCAAGTTGAA
AATGGACGAGTAATCGCCTGCTTTGATTCATTGAAAGGCCGTTGCTCCAGGGAGAACTGCAAATATCTTCATCCACCCCCACATTTAAAA
ACGCAGTTGGAGATAAATGGACGCAATAACTTGATTCAGCAGAAGAACATGGCCATGTTGGCCCAGCAAATGCAACTAGCCAATGCCATG
ATGCCTGGTGCCCCATTACAACCCGTGGTATGTCGAGAGTACCAACGTGGCAATTGCAACCGAGGAGAAAATGATTGTCGGTTTGCTCAT
CCTGCTGACAGCACAATGATTGACACCAATGACAACACAGTCACTGTGTGTATGGATTACATCAAAGGGAGATGCTCTCGGGAAAAGTGC
AAATACTTTCATCCCCCTGCACATTTGCAAGCCAAGATCAAGGCTGCCCAATACCAGGTCAACCAGGCTGCAGCTGCACAGGCTGCAGCC
ACCGCAGCTGCCATGGGAATTCCTCAAGCTGTACTTCCCCCATTACCAAAGAGGCCTGCTCTTGAAAAAACCAACGGTGCCACCGCAGTC
TTTAACACTGGTATTTTCCAATACCAACAGGCTCTAGCCAACATGCAGTTACAACAGCATACAGCATTTCTCCCACCAGGTGTGGTGGAC
ACAGGCCTATTCATCAACATGGCTGAGAGAGTCTACTTTGGGATGCAGGATGGCTCAGTGAACATGAGGGAGAAGCCTTTCTGTTGACCC
TGCAAGGAGCAGAGTGTGTTCACCTTGAGTCTCCAGCCCACAGCCAAGGTGGACGTACCTCTCCAGGAGCCTTTGCCTTAATGTATCTCT
GCCTGGACAACTTGTGGTGGGGGGTGGGGGGAAGAGTGGGAGGGGGAGTTAAATCCAGTCTTATGAAGTATTGTTATTAAATGTCTTTTT
AAAAAGAGAAATATAAACATATATTTTTACTATTAAAATATTCAGTTTTTTAAATGAAGTAGAACTTGAGTTCATGTTTTATATGAAATA
TTTACCAAAAAAAAAAAATGAGGTAAACTGTATTTAAAACCTTTGACTTGAGTCTGCTGGTAAAGCTTCTGAATATTGAGTTTGCTGAGA
AATAAAAATCAAAACTTCTTTAAGCTGGTAAAGTGAGGGGCCCACCAGCAGTGATCTCCTGATGCCTTACTGGAAACTTTGTTTACTTGT
CTGCTACCCTCTGATTTGTTTTTAGTTAGTTTTTATTGTGAGCACACATAGTACCTAGTTACATCTTAAGATCAGGTTTATAAAACTGTG
GAGTGGAGCGGTATGGTATGGAATGACTTGGAATGTAAGCTGTCAGGGAGAAAATGTTGTTACACTTTTGCTAAGATCTGGGGGTTTCTT
CATATTCCTGCTGTTGGAAGCAGTTGACCAGAAATGCTTGCCAGTACTGCCAAAGCACTGCTGTGAAATGTGAAGTACTTTGTTTTTTTA
TTTTTAATGATTTTCTTTTTGTTATTAATATTTTTCTCTGTTCCTTTGTTATTACTTGCATGGTTTGGCGTCAGAAGTCCTTACCTCTTT

>52012_52012_2_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000282488_RPIA_chr2_89049498_ENST00000283646_length(amino acids)=284AA_BP=250
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQ
KNMAMLAQQMQLANAMMPGAPLQPVVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIK
AAQYQVNQAAAAQAAATAAAMGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGVVDTGLFINMAERVYFG

--------------------------------------------------------------
>52012_52012_3_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000324210_RPIA_chr2_89049498_ENST00000283646_length(transcript)=2835nt_BP=1880nt
CCACAATGCTCCCATGACAAGGAGCTGACAAGTTCCATTTTCCGTCGCGGGCATCTTGGAATCATGACTCCCACAATGCCTTGGGCACTT
GGTCGACAGTGGGGCCGCCTCTGAAAAAAAAATGTGAGAGGTTGGTACTAAGAAGTGCCTTTCCTGACGTCTCTGCTGCTTGGAACCGCT
TCTAGAGCAGTCTCTGCTTTTGCCTTGCTTGCTGCCAGCTAGACTGTGACGACAGCACATCCACCCTCCACCTCTAGCCCAGACACCCCC
ATTTCTACTTATAATCAAGAGAAAAGCTCTAAGTATCTGGCATTGCCCTAGGCTGCTTTAGTGTTAAAAGAAAAGTTTGCTGAAAAAGTA
AGATATCTTCTGCCAGGAAATCAAGGAGGAAAAAAAAAATCATTTTCTCGATTTTGCTCTAAACTGCTGCATCTGTCTATGCCAAACTAA
TCAATACCGATTGCACCACCAAACTCCATTGCAAATTCAGCTGTGAGGAGATTCCCTTTCAGACAACTTTGCTGAAAGCAGCTTGGAAAT
TCGGTGTCGAAGGGTCTGCCACGTTTTCATGCTTGCATTTTGGGCTCCAAATTGGCACTGGGAAGGGGTTACTGAGAGCACAAGGCTGAT
ACCAGGCCCTACTTTTAAACGTTCATCTACTTACAATCCTAGTATTTCTCTAAAAACCAAAACCTCTTTGAATTAACAGTTTCATGCTGT
GAATTTCTAGTGGGAGATCTTTTCCTTGATATTGACGACACAATTTTCCATGTACTTTTAAAGCAGGGAGTGGGGAAAAGTATTTTGAGG
GGACATTTTCATCATCAGTTCAGCTTTTTTTTTTTGGTTGTTGCTCTTTTTTGGGGGGGTTGGGTTTGTTGGTTTCACTGAAACATTTAA
CTACCTGTAAAATCTAAACATGGCTGTTAGTGTCACACCAATTCGGGACACAAAATGGCTAACACTGGAAGTATGTAGAGAGTTCCAGAG
GGGGACTTGCTCACGGCCAGACACGGAATGTAAATTTGCACATCCTTCGAAAAGCTGCCAAGTTGAAAATGGACGAGTAATCGCCTGCTT
TGATTCATTGAAAGGCCGTTGCTCCAGGGAGAACTGCAAATATCTTCATCCACCCCCACATTTAAAAACGCAGTTGGAGATAAATGGACG
CAATAACTTGATTCAGCAGAAGAACATGGCCATGTTGGCCCAGCAAATGCAACTAGCCAATGCCATGATGCCTGGTGCCCCATTACAACC
CGTGCCAATGTTTTCAGTTGCACCAAGCTTAGCCACCAATGCATCAGCAGCCGCCTTTAATCCCTATCTGGGACCTGTTTCTCCAAGCCT
GGTCCCGGCAGAGATCTTGCCGACTGCACCAATGTTGGTTACAGGGAATCCGGGTGTCCCTGTACCTGCAGCTGCTGCAGCTGCTGCACA
GAAATTAATGCGAACAGACAGACTTGAGGTATGTCGAGAGTACCAACGTGGCAATTGCAACCGAGGAGAAAATGATTGTCGGTTTGCTCA
TCCTGCTGACAGCACAATGATTGACACCAATGACAACACAGTCACTGTGTGTATGGATTACATCAAAGGGAGATGCTCTCGGGAAAAGTG
CAAATACTTTCATCCCCCTGCACATTTGCAAGCCAAGATCAAGGCTGCCCAATACCAGGTCAACCAGGCTGCAGCTGCACAGGCTGCAGC
CACCGCAGCTGCCATGGGAATTCCTCAAGCTGTACTTCCCCCATTACCAAAGAGGCCTGCTCTTGAAAAAACCAACGGTGCCACCGCAGT
CTTTAACACTGGTATTTTCCAATACCAACAGGCTCTAGCCAACATGCAGTTACAACAGCATACAGCATTTCTCCCACCAGGTGTGGTGGA
CACAGGCCTATTCATCAACATGGCTGAGAGAGTCTACTTTGGGATGCAGGATGGCTCAGTGAACATGAGGGAGAAGCCTTTCTGTTGACC
CTGCAAGGAGCAGAGTGTGTTCACCTTGAGTCTCCAGCCCACAGCCAAGGTGGACGTACCTCTCCAGGAGCCTTTGCCTTAATGTATCTC
TGCCTGGACAACTTGTGGTGGGGGGTGGGGGGAAGAGTGGGAGGGGGAGTTAAATCCAGTCTTATGAAGTATTGTTATTAAATGTCTTTT
TAAAAAGAGAAATATAAACATATATTTTTACTATTAAAATATTCAGTTTTTTAAATGAAGTAGAACTTGAGTTCATGTTTTATATGAAAT
ATTTACCAAAAAAAAAAAATGAGGTAAACTGTATTTAAAACCTTTGACTTGAGTCTGCTGGTAAAGCTTCTGAATATTGAGTTTGCTGAG
AAATAAAAATCAAAACTTCTTTAAGCTGGTAAAGTGAGGGGCCCACCAGCAGTGATCTCCTGATGCCTTACTGGAAACTTTGTTTACTTG
TCTGCTACCCTCTGATTTGTTTTTAGTTAGTTTTTATTGTGAGCACACATAGTACCTAGTTACATCTTAAGATCAGGTTTATAAAACTGT
GGAGTGGAGCGGTATGGTATGGAATGACTTGGAATGTAAGCTGTCAGGGAGAAAATGTTGTTACACTTTTGCTAAGATCTGGGGGTTTCT
TCATATTCCTGCTGTTGGAAGCAGTTGACCAGAAATGCTTGCCAGTACTGCCAAAGCACTGCTGTGAAATGTGAAGTACTTTGTTTTTTT
ATTTTTAATGATTTTCTTTTTGTTATTAATATTTTTCTCTGTTCCTTTGTTATTACTTGCATGGTTTGGCGTCAGAAGTCCTTACCTCTT

>52012_52012_3_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000324210_RPIA_chr2_89049498_ENST00000283646_length(amino acids)=352AA_BP=318
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQ
KNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTD
RLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMG

--------------------------------------------------------------
>52012_52012_4_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000355460_RPIA_chr2_89049498_ENST00000283646_length(transcript)=3330nt_BP=2375nt
CTTGCCGGCTTCCTTGCAAAGCCCGGTGCAAGGGCCTCTTTCAAAATGAACCCACTGGTGTGCCTAGCAGTCGGTAGAAGAAGCGGGAGG
GCGTCCGGTCTGCACGCCCGCCGCGAGGTTACAATGCTGAACGCATGAGATGGAAGATACCAACGGGAGGCCGAGGGGATCCACGGCGCC
CGCGCGGGCTCCGGCTTCCTCCTGCTCTCGGCGCCGCTGGGCGACCGCCCATGACCCGCTCTTGCGGGCTCTGTCCGGTTGACAGGCGAC
CCTGTGGCCCGGGGAAGCGCGGGAGGGCGCCGGCGGAAAGTTGAAGAGCGTTTTTCTCGCCGCCGCGTGCATTAGGAGCTCGACGAGTCC
GCCCTGGGCTTCCTGGTGGGGCTGGGCGGGCGGGGGAGGGGCCGCGCAGCAGCAGCGGAAGCCAGACCTCGGCGATAAGAGGCTGCACAG
CGACATGCAACAGTCTTTTCACTGCAGCTGAATGAGTTGTGGCGCCCACAATGCTCCCATGACAAGGAGCTGACAAGTTCCATTTTCCGT
CGCGGGCATCTTGGAATCATGACTCCCACAATGCCTTGGGCACTTGGTCGACAGTGGGGCCGCCTCTGAAAAAAAAATGTGAGAGGTTGG
TACTAAGAAGTGCCTTTCCTGACGTCTCTGCTGCTTGGAACCGCTTCTAGAGCAGTCTCTGCTTTTGCCTTGCTTGCTGCCAGCTAGACT
GTGACGACAGCACATCCACCCTCCACCTCTAGCCCAGACACCCCCATTTCTACTTATAATCAAGAGAAAAGCTCTAAGTATCTGGCATTG
CCCTAGGCTGCTTTAGTGTTAAAAGAAAAGTTTGCTGAAAAAGTAAGATATCTTCTGCCAGGAAATCAAGGAGGAAAAAAAAAATCATTT
TCTCGATTTTGCTCTAAACTGCTGCATCTGTCTATGCCAAACTAATCAATACCGATTGCACCACCAAACTCCATTGCAAATTCAGCTGTG
AGGAGATTCCCTTTCAGACAACTTTGCTGAAAGCAGCTTGGAAATTCGGTGTCGAAGGGTCTGCCACGTTTTCATGCTTGCATTTTGGGC
TCCAAATTGGCACTGGGAAGGGGTTACTGAGAGCACAAGGCTGATACCAGGCCCTACTTTTAAACGTTCATCTACTTACAATCCTAGTAT
TTCTCTAAAAACCAAAACCTCTTTGAATTAACAGTTTCATGCTGTGAATTTCTAGTGGGAGATCTTTTCCTTGATATTGACGACACAATT
TTCCATGTACTTTTAAAGCAGGGAGTGGGGAAAAGTATTTTGAGGGGACATTTTCATCATCAGTTCAGCTTTTTTTTTTTGGTTGTTGCT
CTTTTTTGGGGGGGTTGGGTTTGTTGGTTTCACTGAAACATTTAACTACCTGTAAAATCTAAACATGGCTGTTAGTGTCACACCAATTCG
GGACACAAAATGGCTAACACTGGAAGTATGTAGAGAGTTCCAGAGGGGGACTTGCTCACGGCCAGACACGGAATGTAAATTTGCACATCC
TTCGAAAAGCTGCCAAGTTGAAAATGGACGAGTAATCGCCTGCTTTGATTCATTGAAAGGCCGTTGCTCCAGGGAGAACTGCAAATATCT
TCATCCACCCCCACATTTAAAAACGCAGTTGGAGATAAATGGACGCAATAACTTGATTCAGCAGAAGAACATGGCCATGTTGGCCCAGCA
AATGCAACTAGCCAATGCCATGATGCCTGGTGCCCCATTACAACCCGTGCCAATGTTTTCAGTTGCACCAAGCTTAGCCACCAATGCATC
AGCAGCCGCCTTTAATCCCTATCTGGGACCTGTTTCTCCAAGCCTGGTCCCGGCAGAGATCTTGCCGACTGCACCAATGTTGGTTACAGG
GAATCCGGGTGTCCCTGTACCTGCAGCTGCTGCAGCTGCTGCACAGAAATTAATGCGAACAGACAGACTTGAGGTATGTCGAGAGTACCA
ACGTGGCAATTGCAACCGAGGAGAAAATGATTGTCGGTTTGCTCATCCTGCTGACAGCACAATGATTGACACCAATGACAACACAGTCAC
TGTGTGTATGGATTACATCAAAGGGAGATGCTCTCGGGAAAAGTGCAAATACTTTCATCCCCCTGCACATTTGCAAGCCAAGATCAAGGC
TGCCCAATACCAGGTCAACCAGGCTGCAGCTGCACAGGCTGCAGCCACCGCAGCTGCCATGGGAATTCCTCAAGCTGTACTTCCCCCATT
ACCAAAGAGGCCTGCTCTTGAAAAAACCAACGGTGCCACCGCAGTCTTTAACACTGGTATTTTCCAATACCAACAGGCTCTAGCCAACAT
GCAGTTACAACAGCATACAGCATTTCTCCCACCAGGTGTGGTGGACACAGGCCTATTCATCAACATGGCTGAGAGAGTCTACTTTGGGAT
GCAGGATGGCTCAGTGAACATGAGGGAGAAGCCTTTCTGTTGACCCTGCAAGGAGCAGAGTGTGTTCACCTTGAGTCTCCAGCCCACAGC
CAAGGTGGACGTACCTCTCCAGGAGCCTTTGCCTTAATGTATCTCTGCCTGGACAACTTGTGGTGGGGGGTGGGGGGAAGAGTGGGAGGG
GGAGTTAAATCCAGTCTTATGAAGTATTGTTATTAAATGTCTTTTTAAAAAGAGAAATATAAACATATATTTTTACTATTAAAATATTCA
GTTTTTTAAATGAAGTAGAACTTGAGTTCATGTTTTATATGAAATATTTACCAAAAAAAAAAAATGAGGTAAACTGTATTTAAAACCTTT
GACTTGAGTCTGCTGGTAAAGCTTCTGAATATTGAGTTTGCTGAGAAATAAAAATCAAAACTTCTTTAAGCTGGTAAAGTGAGGGGCCCA
CCAGCAGTGATCTCCTGATGCCTTACTGGAAACTTTGTTTACTTGTCTGCTACCCTCTGATTTGTTTTTAGTTAGTTTTTATTGTGAGCA
CACATAGTACCTAGTTACATCTTAAGATCAGGTTTATAAAACTGTGGAGTGGAGCGGTATGGTATGGAATGACTTGGAATGTAAGCTGTC
AGGGAGAAAATGTTGTTACACTTTTGCTAAGATCTGGGGGTTTCTTCATATTCCTGCTGTTGGAAGCAGTTGACCAGAAATGCTTGCCAG
TACTGCCAAAGCACTGCTGTGAAATGTGAAGTACTTTGTTTTTTTATTTTTAATGATTTTCTTTTTGTTATTAATATTTTTCTCTGTTCC
TTTGTTATTACTTGCATGGTTTGGCGTCAGAAGTCCTTACCTCTTTATATTGTTTGCAGGTTTAAATAAAACAGTGTGGTGCCATTTTGA

>52012_52012_4_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000355460_RPIA_chr2_89049498_ENST00000283646_length(amino acids)=352AA_BP=318
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQ
KNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTD
RLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMG

--------------------------------------------------------------
>52012_52012_5_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000357472_RPIA_chr2_89049498_ENST00000283646_length(transcript)=2705nt_BP=1750nt
GTTGGTACTAAGAAGTGCCTTTCCTGACGTCTCTGCTGCTTGGAACCGCTTCTAGAGCAGTCTCTGCTTTTGCCTTGCTTGCTGCCAGCT
AGACTGTGACGACAGCACATCCACCCTCCACCTCTAGCCCAGACACCCCCATTTCTACTTATAATCAAGAGAAAAGCTCTAAGTATCTGG
CATTGCCCTAGGCTGCTTTAGTGTTAAAAGAAAAGTTTGCTGAAAAAGTAAGATATCTTCTGCCAGGAAATCAAGGAGGAAAAAAAAAAT
CATTTTCTCGATTTTGCTCTAAACTGCTGCATCTGTCTATGCCAAACTAATCAATACCGATTGCACCACCAAACTCCATTGCAAATTCAG
CTGTGAGGAGATTCCCTTTCAGACAACTTTGCTGAAAGCAGCTTGGAAATTCGGTGTCGAAGGGTCTGCCACGTTTTCATGCTTGCATTT
TGGGCTCCAAATTGGCACTGGGAAGGGGTTACTGAGAGCACAAGGCTGATACCAGGCCCTACTTTTAAACGTTCATCTACTTACAATCCT
AGTATTTCTCTAAAAACCAAAACCTCTTTGAATTAACAGTTTCATGCTGTGAATTTCTAGTGGGAGATCTTTTCCTTGATATTGACGACA
CAATTTTCCATGTACTTTTAAAGCAGGGAGTGGGGAAAAGTATTTTGAGGGGACATTTTCATCATCAGTTCAGCTTTTTTTTTTTGGTTG
TTGCTCTTTTTTGGGGGGGTTGGGTTTGTTGGTTTCACTGAAACATTTAACTACCTGTAAAATCTAAACATGGCTGTTAGTGTCACACCA
ATTCGGGACACAAAATGGCTAACACTGGAAGTATGTAGAGAGTTCCAGAGGGGGACTTGCTCACGGCCAGACACGGAATGTAAATTTGCA
CATCCTTCGAAAAGCTGCCAAGTTGAAAATGGACGAGTAATCGCCTGCTTTGATTCATTGAAAGGCCGTTGCTCCAGGGAGAACTGCAAA
TATCTTCATCCACCCCCACATTTAAAAACGCAGTTGGAGATAAATGGACGCAATAACTTGATTCAGCAGAAGAACATGGCCATGTTGGCC
CAGCAAATGCAACTAGCCAATGCCATGATGCCTGGTGCCCCATTACAACCCGTGCCAATGTTTTCAGTTGCACCAAGCTTAGCCACCAAT
GCATCAGCAGCCGCCTTTAATCCCTATCTGGGACCTGTTTCTCCAAGCCTGGTCCCGGCAGAGATCTTGCCGACTGCACCAATGTTGGTT
ACAGGGAATCCGGGTGTCCCTGTACCTGCAGCTGCTGCAGCTGCTGCACAGAAATTAATGCGAACAGACAGACTTGAGGTATGTCGAGAG
TACCAACGTGGCAATTGCAACCGAGGAGAAAATGATTGTCGGTTTGCTCATCCTGCTGACAGCACAATGATTGACACCAATGACAACACA
GTCACTGTGTGTATGGATTACATCAAAGGGAGATGCTCTCGGGAAAAGTGCAAATACTTTCATCCCCCTGCACATTTGCAAGCCAAGATC
AAGGCTGCCCAATACCAGGTCAACCAGGCTGCAGCTGCACAGGCTGCAGCCACCGCAGCTGCCATGGGAATTCCTCAAGCTGTACTTCCC
CCATTACCAAAGAGGCCTGCTCTTGAAAAAACCAACGGTGCCACCGCAGTCTTTAACACTGGTATTTTCCAATACCAACAGGCTCTAGCC
AACATGCAGTTACAACAGCATACAGCATTTCTCCCACCAGGTGTGGTGGACACAGGCCTATTCATCAACATGGCTGAGAGAGTCTACTTT
GGGATGCAGGATGGCTCAGTGAACATGAGGGAGAAGCCTTTCTGTTGACCCTGCAAGGAGCAGAGTGTGTTCACCTTGAGTCTCCAGCCC
ACAGCCAAGGTGGACGTACCTCTCCAGGAGCCTTTGCCTTAATGTATCTCTGCCTGGACAACTTGTGGTGGGGGGTGGGGGGAAGAGTGG
GAGGGGGAGTTAAATCCAGTCTTATGAAGTATTGTTATTAAATGTCTTTTTAAAAAGAGAAATATAAACATATATTTTTACTATTAAAAT
ATTCAGTTTTTTAAATGAAGTAGAACTTGAGTTCATGTTTTATATGAAATATTTACCAAAAAAAAAAAATGAGGTAAACTGTATTTAAAA
CCTTTGACTTGAGTCTGCTGGTAAAGCTTCTGAATATTGAGTTTGCTGAGAAATAAAAATCAAAACTTCTTTAAGCTGGTAAAGTGAGGG
GCCCACCAGCAGTGATCTCCTGATGCCTTACTGGAAACTTTGTTTACTTGTCTGCTACCCTCTGATTTGTTTTTAGTTAGTTTTTATTGT
GAGCACACATAGTACCTAGTTACATCTTAAGATCAGGTTTATAAAACTGTGGAGTGGAGCGGTATGGTATGGAATGACTTGGAATGTAAG
CTGTCAGGGAGAAAATGTTGTTACACTTTTGCTAAGATCTGGGGGTTTCTTCATATTCCTGCTGTTGGAAGCAGTTGACCAGAAATGCTT
GCCAGTACTGCCAAAGCACTGCTGTGAAATGTGAAGTACTTTGTTTTTTTATTTTTAATGATTTTCTTTTTGTTATTAATATTTTTCTCT
GTTCCTTTGTTATTACTTGCATGGTTTGGCGTCAGAAGTCCTTACCTCTTTATATTGTTTGCAGGTTTAAATAAAACAGTGTGGTGCCAT

>52012_52012_5_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000357472_RPIA_chr2_89049498_ENST00000283646_length(amino acids)=352AA_BP=318
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQ
KNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTD
RLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMG

--------------------------------------------------------------
>52012_52012_6_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000463374_RPIA_chr2_89049498_ENST00000283646_length(transcript)=2481nt_BP=1526nt
CGATTTTGCTCTAAACTGCTGCATCTGTCTATGCCAAACTAATCAATACCGATTGCACCACCAAACTCCATTGCAAATTCAGCTGTGAGG
AGATTCCCTTTCAGACAACTTTGCTGAAAGCAGCTTGGAAATTCGGTGTCGAAGGGTCTGCCACGTTTTCATGCTTGCATTTTGGGCTCC
AAATTGGCACTGGGAAGGGGTTACTGAGAGCACAAGGCTGATACCAGGCCCTACTTTTAAACGTTCATCTACTTACAATCCTAGTATTTC
TCTAAAAACCAAAACCTCTTTGAATTAACAGTTTCATGCTGTGAATTTCTAGTGGGAGATCTTTTCCTTGATATTGACGACACAATTTTC
CATGTACTTTTAAAGCAGGGAGTGGGGAAAAGTATTTTGAGGGGACATTTTCATCATCAGTTCAGCTTTTTTTTTTTGGTTGTTGCTCTT
TTTTGGGGGGGTTGGGTTTGTTGGTTTCACTGAAACATTTAACTACCTGTAAAATCTAAACATGGCTGTTAGTGTCACACCAATTCGGGA
CACAAAATGGCTAACACTGGAAGTATGTAGAGAGTTCCAGAGGGGGACTTGCTCACGGCCAGACACGGAATGTAAATTTGCACATCCTTC
GAAAAGCTGCCAAGTTGAAAATGGACGAGTAATCGCCTGCTTTGATTCATTGAAAGGCCGTTGCTCCAGGGAGAACTGCAAATATCTTCA
TCCACCCCCACATTTAAAAACGCAGTTGGAGATAAATGGACGCAATAACTTGATTCAGCAGAAGAACATGGCCATGTTGGCCCAGCAAAT
GCAACTAGCCAATGCCATGATGCCTGGTGCCCCATTACAACCCGTGCCAATGTTTTCAGTTGCACCAAGCTTAGCCACCAATGCATCAGC
AGCCGCCTTTAATCCCTATCTGGGACCTGTTTCTCCAAGCCTGGTCCCGGCAGAGATCTTGCCGACTGCACCAATGTTGGTTACAGGGAA
TCCGGGTGTCCCTGTACCTGCAGCTGCTGCAGCTGCTGCACAGAAATTAATGCGAACAGACAGACTTGAGGTATGTCGAGAGTACCAACG
TGGCAATTGCAACCGAGGAGAAAATGATTGTCGGTTTGCTCATCCTGCTGACAGCACAATGATTGACACCAATGACAACACAGTCACTGT
GTGTATGGATTACATCAAAGGGAGATGCTCTCGGGAAAAGTGCAAATACTTTCATCCCCCTGCACATTTGCAAGCCAAGATCAAGGCTGC
CCAATACCAGGTCAACCAGGCTGCAGCTGCACAGGCTGCAGCCACCGCAGCTGCCATGACTCAGTCGGCTGTCAAATCACTGAAGCGACC
CCTCGAGGCAACCTTTGACCTGGGAATTCCTCAAGCTGTACTTCCCCCATTACCAAAGAGGCCTGCTCTTGAAAAAACCAACGGTGCCAC
CGCAGTCTTTAACACTGGTATTTTCCAATACCAACAGGCTCTAGCCAACATGCAGTTACAACAGCATACAGCATTTCTCCCACCAGGTGT
GGTGGACACAGGCCTATTCATCAACATGGCTGAGAGAGTCTACTTTGGGATGCAGGATGGCTCAGTGAACATGAGGGAGAAGCCTTTCTG
TTGACCCTGCAAGGAGCAGAGTGTGTTCACCTTGAGTCTCCAGCCCACAGCCAAGGTGGACGTACCTCTCCAGGAGCCTTTGCCTTAATG
TATCTCTGCCTGGACAACTTGTGGTGGGGGGTGGGGGGAAGAGTGGGAGGGGGAGTTAAATCCAGTCTTATGAAGTATTGTTATTAAATG
TCTTTTTAAAAAGAGAAATATAAACATATATTTTTACTATTAAAATATTCAGTTTTTTAAATGAAGTAGAACTTGAGTTCATGTTTTATA
TGAAATATTTACCAAAAAAAAAAAATGAGGTAAACTGTATTTAAAACCTTTGACTTGAGTCTGCTGGTAAAGCTTCTGAATATTGAGTTT
GCTGAGAAATAAAAATCAAAACTTCTTTAAGCTGGTAAAGTGAGGGGCCCACCAGCAGTGATCTCCTGATGCCTTACTGGAAACTTTGTT
TACTTGTCTGCTACCCTCTGATTTGTTTTTAGTTAGTTTTTATTGTGAGCACACATAGTACCTAGTTACATCTTAAGATCAGGTTTATAA
AACTGTGGAGTGGAGCGGTATGGTATGGAATGACTTGGAATGTAAGCTGTCAGGGAGAAAATGTTGTTACACTTTTGCTAAGATCTGGGG
GTTTCTTCATATTCCTGCTGTTGGAAGCAGTTGACCAGAAATGCTTGCCAGTACTGCCAAAGCACTGCTGTGAAATGTGAAGTACTTTGT
TTTTTTATTTTTAATGATTTTCTTTTTGTTATTAATATTTTTCTCTGTTCCTTTGTTATTACTTGCATGGTTTGGCGTCAGAAGTCCTTA

>52012_52012_6_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000463374_RPIA_chr2_89049498_ENST00000283646_length(amino acids)=370AA_BP=336
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQ
KNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTD
RLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMT
QSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGVVDTGLFINMAERVYFGMQDG

--------------------------------------------------------------
>52012_52012_7_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000485910_RPIA_chr2_89049498_ENST00000283646_length(transcript)=2223nt_BP=1268nt
CGATTTTGCTCTAAACTGCTGCATCTGTCTATGCCAAACTAATCAATACCGATTGCACCACCAAACTCCATTGCAAATTCAGCTGTGAGG
AGATTCCCTTTCAGACAACTTTGCTGAAAGCAGCTTGGAAATTCGGTGTCGAAGGGTCTGCCACGTTTTCATGCTTGCATTTTGGGCTCC
AAATTGGCACTGGGAAGGGGTTACTGAGAGCACAAGGCTGATACCAGGCCCTACTTTTAAACGTTCATCTACTTACAATCCTAGTATTTC
TCTAAAAACCAAAACCTCTTTGAATTAACAGTTTCATGCTGTGAATTTCTAGTGGGAGATCTTTTCCTTGATATTGACGACACAATTTTC
CATGTACTTTTAAAGCAGGGAGTGGGGAAAAGTATTTTGAGGGGACATTTTCATCATCAGTTCAGCTTTTTTTTTTTGGTTGTTGCTCTT
TTTTGGGGGGGTTGGGTTTGTTGGTTTCACTGAAACATTTAACTACCTGTAAAATCTAAACATGGCTGTTAGTGTCACACCAATTCGGGA
CACAAAATGGCTAACACTGGAAGTATGTAGAGAGTTCCAGAGGGGGACTTGCTCACGGCCAGACACGGAATGTAAATTTGCACATCCTTC
GAAAAGCTGCCAAGTTGAAAATGGACGAGTAATCGCCTGCTTTGATTCATTGAAAGGCCGTTGCTCCAGGGAGAACTGCAAATATCTTCA
TCCACCCCCACATTTAAAAACGCAGTTGGAGATAAATGGACGCAATAACTTGATTCAGCAGAAGAACATGGCCATGTTGGCCCAGCAAAT
GCAACTAGCCAATGCCATGATGCCTGGTGCCCCATTACAACCCGTGGTATGTCGAGAGTACCAACGTGGCAATTGCAACCGAGGAGAAAA
TGATTGTCGGTTTGCTCATCCTGCTGACAGCACAATGATTGACACCAATGACAACACAGTCACTGTGTGTATGGATTACATCAAAGGGAG
ATGCTCTCGGGAAAAGTGCAAATACTTTCATCCCCCTGCACATTTGCAAGCCAAGATCAAGGCTGCCCAATACCAGGTCAACCAGGCTGC
AGCTGCACAGGCTGCAGCCACCGCAGCTGCCATGGGAATTCCTCAAGCTGTACTTCCCCCATTACCAAAGAGGCCTGCTCTTGAAAAAAC
CAACGGTGCCACCGCAGTCTTTAACACTGGTATTTTCCAATACCAACAGGCTCTAGCCAACATGCAGTTACAACAGCATACAGCATTTCT
CCCACCAGGTGTGGTGGACACAGGCCTATTCATCAACATGGCTGAGAGAGTCTACTTTGGGATGCAGGATGGCTCAGTGAACATGAGGGA
GAAGCCTTTCTGTTGACCCTGCAAGGAGCAGAGTGTGTTCACCTTGAGTCTCCAGCCCACAGCCAAGGTGGACGTACCTCTCCAGGAGCC
TTTGCCTTAATGTATCTCTGCCTGGACAACTTGTGGTGGGGGGTGGGGGGAAGAGTGGGAGGGGGAGTTAAATCCAGTCTTATGAAGTAT
TGTTATTAAATGTCTTTTTAAAAAGAGAAATATAAACATATATTTTTACTATTAAAATATTCAGTTTTTTAAATGAAGTAGAACTTGAGT
TCATGTTTTATATGAAATATTTACCAAAAAAAAAAAATGAGGTAAACTGTATTTAAAACCTTTGACTTGAGTCTGCTGGTAAAGCTTCTG
AATATTGAGTTTGCTGAGAAATAAAAATCAAAACTTCTTTAAGCTGGTAAAGTGAGGGGCCCACCAGCAGTGATCTCCTGATGCCTTACT
GGAAACTTTGTTTACTTGTCTGCTACCCTCTGATTTGTTTTTAGTTAGTTTTTATTGTGAGCACACATAGTACCTAGTTACATCTTAAGA
TCAGGTTTATAAAACTGTGGAGTGGAGCGGTATGGTATGGAATGACTTGGAATGTAAGCTGTCAGGGAGAAAATGTTGTTACACTTTTGC
TAAGATCTGGGGGTTTCTTCATATTCCTGCTGTTGGAAGCAGTTGACCAGAAATGCTTGCCAGTACTGCCAAAGCACTGCTGTGAAATGT
GAAGTACTTTGTTTTTTTATTTTTAATGATTTTCTTTTTGTTATTAATATTTTTCTCTGTTCCTTTGTTATTACTTGCATGGTTTGGCGT

>52012_52012_7_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000485910_RPIA_chr2_89049498_ENST00000283646_length(amino acids)=284AA_BP=250
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQ
KNMAMLAQQMQLANAMMPGAPLQPVVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIK
AAQYQVNQAAAAQAAATAAAMGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGVVDTGLFINMAERVYFG

--------------------------------------------------------------
>52012_52012_8_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000492948_RPIA_chr2_89049498_ENST00000283646_length(transcript)=1916nt_BP=961nt
ATGGCTGTTAGTGTCACACCAATTCGGGACACAAAATGGCTAACACTGGAAGTATGTAGAGAGTTCCAGAGGGGGACTTGCTCACGGCCA
GACACGGAATGTAAATTTGCACATCCTTCGAAAAGCTGCCAAGTTGAAAATGGACGAGTAATCGCCTGCTTTGATTCATTGAAAGGCCGT
TGCTCCAGGGAGAACTGCAAATATCTTCATCCACCCCCACATTTAAAAACGCAGTTGGAGATAAATGGACGCAATAACTTGATTCAGCAG
AAGAACATGGCCATGTTGGCCCAGCAAATGCAACTAGCCAATGCCATGATGCCTGGTGCCCCATTACAACCCGTGCCAATGTTTTCAGTT
GCACCAAGCTTAGCCACCAATGCATCAGCAGCCGCCTTTAATCCCTATCTGGGACCTGTTTCTCCAAGCCTGGTCCCGGCAGAGATCTTG
CCGACTGCACCAATGTTGGTTACAGGGAATCCGGGTGTCCCTGTACCTGCAGCTGCTGCAGCTGCTGCACAGAAATTAATGCGAACAGAC
AGACTTGAGGTATGTCGAGAGTACCAACGTGGCAATTGCAACCGAGGAGAAAATGATTGTCGGTTTGCTCATCCTGCTGACAGCACAATG
ATTGACACCAATGACAACACAGTCACTGTGTGTATGGATTACATCAAAGGGAGATGCTCTCGGGAAAAGTGCAAATACTTTCATCCCCCT
GCACATTTGCAAGCCAAGATCAAGGCTGCCCAATACCAGGTCAACCAGGCTGCAGCTGCACAGGCTGCAGCCACCGCAGCTGCCATGGGA
ATTCCTCAAGCTGTACTTCCCCCATTACCAAAGAGGCCTGCTCTTGAAAAAACCAACGGTGCCACCGCAGTCTTTAACACTGGTATTTTC
CAATACCAACAGGCTCTAGCCAACATGCAGTTACAACAGCATACAGCATTTCTCCCACCAGGTGTGGTGGACACAGGCCTATTCATCAAC
ATGGCTGAGAGAGTCTACTTTGGGATGCAGGATGGCTCAGTGAACATGAGGGAGAAGCCTTTCTGTTGACCCTGCAAGGAGCAGAGTGTG
TTCACCTTGAGTCTCCAGCCCACAGCCAAGGTGGACGTACCTCTCCAGGAGCCTTTGCCTTAATGTATCTCTGCCTGGACAACTTGTGGT
GGGGGGTGGGGGGAAGAGTGGGAGGGGGAGTTAAATCCAGTCTTATGAAGTATTGTTATTAAATGTCTTTTTAAAAAGAGAAATATAAAC
ATATATTTTTACTATTAAAATATTCAGTTTTTTAAATGAAGTAGAACTTGAGTTCATGTTTTATATGAAATATTTACCAAAAAAAAAAAA
TGAGGTAAACTGTATTTAAAACCTTTGACTTGAGTCTGCTGGTAAAGCTTCTGAATATTGAGTTTGCTGAGAAATAAAAATCAAAACTTC
TTTAAGCTGGTAAAGTGAGGGGCCCACCAGCAGTGATCTCCTGATGCCTTACTGGAAACTTTGTTTACTTGTCTGCTACCCTCTGATTTG
TTTTTAGTTAGTTTTTATTGTGAGCACACATAGTACCTAGTTACATCTTAAGATCAGGTTTATAAAACTGTGGAGTGGAGCGGTATGGTA
TGGAATGACTTGGAATGTAAGCTGTCAGGGAGAAAATGTTGTTACACTTTTGCTAAGATCTGGGGGTTTCTTCATATTCCTGCTGTTGGA
AGCAGTTGACCAGAAATGCTTGCCAGTACTGCCAAAGCACTGCTGTGAAATGTGAAGTACTTTGTTTTTTTATTTTTAATGATTTTCTTT
TTGTTATTAATATTTTTCTCTGTTCCTTTGTTATTACTTGCATGGTTTGGCGTCAGAAGTCCTTACCTCTTTATATTGTTTGCAGGTTTA

>52012_52012_8_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000492948_RPIA_chr2_89049498_ENST00000283646_length(amino acids)=352AA_BP=318
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQ
KNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTD
RLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMG

--------------------------------------------------------------
>52012_52012_9_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000493459_RPIA_chr2_89049498_ENST00000283646_length(transcript)=2120nt_BP=1165nt
GAATGAGTTGTGGCGCCCACAATGCTCCCATGACAAGGAGCTGACAAGTTCCATTTTCCGTCGCGGGCATCTTGGAATCATGACTCCCAC
AATGCCTTGGGCACTTGGTCGACAGTGGGGCCGCCTCTGAAAAAAAAATGTGAGAGCAGTCACTCAGGAAATGTTGTTTAAGGGGAACCT
TCTGGATCCTTTTCATGGCACCATGGCAAGAAGAAGCTGTATCTTATCTATGGAAGATAAAGCATGGAGTTGGCTAATGGATGCTGATAG
GACCATCTAGTTGCAGGAAAACAAGCTCAGGGCTCCCACTGATTCTACATTATGGGCCGTTGCTCCAGGGAGAACTGCAAATATCTTCAT
CCACCCCCACATTTAAAAACGCAGTTGGAGATAAATGGACGCAATAACTTGATTCAGCAGAAGAACATGGCCATGTTGGCCCAGCAAATG
CAACTAGCCAATGCCATGATGCCTGGTGCCCCATTACAACCCGTGCCAATGTTTTCAGTTGCACCAAGCTTAGCCACCAATGCATCAGCA
GCCGCCTTTAATCCCTATCTGGGACCTGTTTCTCCAAGCCTGGTCCCGGCAGAGATCTTGCCGACTGCACCAATGTTGGTTACAGGGAAT
CCGGGTGTCCCTGTACCTGCAGCTGCTGCAGCTGCTGCACAGAAATTAATGCGAACAGACAGACTTGAGGTATGTCGAGAGTACCAACGT
GGCAATTGCAACCGAGGAGAAAATGATTGTCGGTTTGCTCATCCTGCTGACAGCACAATGATTGACACCAATGACAACACAGTCACTGTG
TGTATGGATTACATCAAAGGGAGATGCTCTCGGGAAAAGTGCAAATACTTTCATCCCCCTGCACATTTGCAAGCCAAGATCAAGGCTGCC
CAATACCAGGTCAACCAGGCTGCAGCTGCACAGGCTGCAGCCACCGCAGCTGCCATGACTCAGTCGGCTGTCAAATCACTGAAGCGACCC
CTCGAGGCAACCTTTGACCTGGGAATTCCTCAAGCTGTACTTCCCCCATTACCAAAGAGGCCTGCTCTTGAAAAAACCAACGGTGCCACC
GCAGTCTTTAACACTGGTATTTTCCAATACCAACAGGCTCTAGCCAACATGCAGTTACAACAGCATACAGCATTTCTCCCACCAGGTGTG
GTGGACACAGGCCTATTCATCAACATGGCTGAGAGAGTCTACTTTGGGATGCAGGATGGCTCAGTGAACATGAGGGAGAAGCCTTTCTGT
TGACCCTGCAAGGAGCAGAGTGTGTTCACCTTGAGTCTCCAGCCCACAGCCAAGGTGGACGTACCTCTCCAGGAGCCTTTGCCTTAATGT
ATCTCTGCCTGGACAACTTGTGGTGGGGGGTGGGGGGAAGAGTGGGAGGGGGAGTTAAATCCAGTCTTATGAAGTATTGTTATTAAATGT
CTTTTTAAAAAGAGAAATATAAACATATATTTTTACTATTAAAATATTCAGTTTTTTAAATGAAGTAGAACTTGAGTTCATGTTTTATAT
GAAATATTTACCAAAAAAAAAAAATGAGGTAAACTGTATTTAAAACCTTTGACTTGAGTCTGCTGGTAAAGCTTCTGAATATTGAGTTTG
CTGAGAAATAAAAATCAAAACTTCTTTAAGCTGGTAAAGTGAGGGGCCCACCAGCAGTGATCTCCTGATGCCTTACTGGAAACTTTGTTT
ACTTGTCTGCTACCCTCTGATTTGTTTTTAGTTAGTTTTTATTGTGAGCACACATAGTACCTAGTTACATCTTAAGATCAGGTTTATAAA
ACTGTGGAGTGGAGCGGTATGGTATGGAATGACTTGGAATGTAAGCTGTCAGGGAGAAAATGTTGTTACACTTTTGCTAAGATCTGGGGG
TTTCTTCATATTCCTGCTGTTGGAAGCAGTTGACCAGAAATGCTTGCCAGTACTGCCAAAGCACTGCTGTGAAATGTGAAGTACTTTGTT
TTTTTATTTTTAATGATTTTCTTTTTGTTATTAATATTTTTCTCTGTTCCTTTGTTATTACTTGCATGGTTTGGCGTCAGAAGTCCTTAC

>52012_52012_9_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000493459_RPIA_chr2_89049498_ENST00000283646_length(amino acids)=313AA_BP=279
MGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPA
EILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYF
HPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANM

--------------------------------------------------------------
>52012_52012_10_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000498502_RPIA_chr2_89049498_ENST00000283646_length(transcript)=2759nt_BP=1804nt
GTTGGTACTAAGAAGTGCCTTTCCTGACGTCTCTGCTGCTTGGAACCGCTTCTAGAGCAGTCTCTGCTTTTGCCTTGCTTGCTGCCAGCT
AGACTGTGACGACAGCACATCCACCCTCCACCTCTAGCCCAGACACCCCCATTTCTACTTATAATCAAGAGAAAAGCTCTAAGTATCTGG
CATTGCCCTAGGCTGCTTTAGTGTTAAAAGAAAAGTTTGCTGAAAAAGTAAGATATCTTCTGCCAGGAAATCAAGGAGGAAAAAAAAAAT
CATTTTCTCGATTTTGCTCTAAACTGCTGCATCTGTCTATGCCAAACTAATCAATACCGATTGCACCACCAAACTCCATTGCAAATTCAG
CTGTGAGGAGATTCCCTTTCAGACAACTTTGCTGAAAGCAGCTTGGAAATTCGGTGTCGAAGGGTCTGCCACGTTTTCATGCTTGCATTT
TGGGCTCCAAATTGGCACTGGGAAGGGGTTACTGAGAGCACAAGGCTGATACCAGGCCCTACTTTTAAACGTTCATCTACTTACAATCCT
AGTATTTCTCTAAAAACCAAAACCTCTTTGAATTAACAGTTTCATGCTGTGAATTTCTAGTGGGAGATCTTTTCCTTGATATTGACGACA
CAATTTTCCATGTACTTTTAAAGCAGGGAGTGGGGAAAAGTATTTTGAGGGGACATTTTCATCATCAGTTCAGCTTTTTTTTTTTGGTTG
TTGCTCTTTTTTGGGGGGGTTGGGTTTGTTGGTTTCACTGAAACATTTAACTACCTGTAAAATCTAAACATGGCTGTTAGTGTCACACCA
ATTCGGGACACAAAATGGCTAACACTGGAAGTATGTAGAGAGTTCCAGAGGGGGACTTGCTCACGGCCAGACACGGAATGTAAATTTGCA
CATCCTTCGAAAAGCTGCCAAGTTGAAAATGGACGAGTAATCGCCTGCTTTGATTCATTGAAAGGCCGTTGCTCCAGGGAGAACTGCAAA
TATCTTCATCCACCCCCACATTTAAAAACGCAGTTGGAGATAAATGGACGCAATAACTTGATTCAGCAGAAGAACATGGCCATGTTGGCC
CAGCAAATGCAACTAGCCAATGCCATGATGCCTGGTGCCCCATTACAACCCGTGCCAATGTTTTCAGTTGCACCAAGCTTAGCCACCAAT
GCATCAGCAGCCGCCTTTAATCCCTATCTGGGACCTGTTTCTCCAAGCCTGGTCCCGGCAGAGATCTTGCCGACTGCACCAATGTTGGTT
ACAGGGAATCCGGGTGTCCCTGTACCTGCAGCTGCTGCAGCTGCTGCACAGAAATTAATGCGAACAGACAGACTTGAGGTATGTCGAGAG
TACCAACGTGGCAATTGCAACCGAGGAGAAAATGATTGTCGGTTTGCTCATCCTGCTGACAGCACAATGATTGACACCAATGACAACACA
GTCACTGTGTGTATGGATTACATCAAAGGGAGATGCTCTCGGGAAAAGTGCAAATACTTTCATCCCCCTGCACATTTGCAAGCCAAGATC
AAGGCTGCCCAATACCAGGTCAACCAGGCTGCAGCTGCACAGGCTGCAGCCACCGCAGCTGCCATGACTCAGTCGGCTGTCAAATCACTG
AAGCGACCCCTCGAGGCAACCTTTGACCTGGGAATTCCTCAAGCTGTACTTCCCCCATTACCAAAGAGGCCTGCTCTTGAAAAAACCAAC
GGTGCCACCGCAGTCTTTAACACTGGTATTTTCCAATACCAACAGGCTCTAGCCAACATGCAGTTACAACAGCATACAGCATTTCTCCCA
CCAGGTGTGGTGGACACAGGCCTATTCATCAACATGGCTGAGAGAGTCTACTTTGGGATGCAGGATGGCTCAGTGAACATGAGGGAGAAG
CCTTTCTGTTGACCCTGCAAGGAGCAGAGTGTGTTCACCTTGAGTCTCCAGCCCACAGCCAAGGTGGACGTACCTCTCCAGGAGCCTTTG
CCTTAATGTATCTCTGCCTGGACAACTTGTGGTGGGGGGTGGGGGGAAGAGTGGGAGGGGGAGTTAAATCCAGTCTTATGAAGTATTGTT
ATTAAATGTCTTTTTAAAAAGAGAAATATAAACATATATTTTTACTATTAAAATATTCAGTTTTTTAAATGAAGTAGAACTTGAGTTCAT
GTTTTATATGAAATATTTACCAAAAAAAAAAAATGAGGTAAACTGTATTTAAAACCTTTGACTTGAGTCTGCTGGTAAAGCTTCTGAATA
TTGAGTTTGCTGAGAAATAAAAATCAAAACTTCTTTAAGCTGGTAAAGTGAGGGGCCCACCAGCAGTGATCTCCTGATGCCTTACTGGAA
ACTTTGTTTACTTGTCTGCTACCCTCTGATTTGTTTTTAGTTAGTTTTTATTGTGAGCACACATAGTACCTAGTTACATCTTAAGATCAG
GTTTATAAAACTGTGGAGTGGAGCGGTATGGTATGGAATGACTTGGAATGTAAGCTGTCAGGGAGAAAATGTTGTTACACTTTTGCTAAG
ATCTGGGGGTTTCTTCATATTCCTGCTGTTGGAAGCAGTTGACCAGAAATGCTTGCCAGTACTGCCAAAGCACTGCTGTGAAATGTGAAG
TACTTTGTTTTTTTATTTTTAATGATTTTCTTTTTGTTATTAATATTTTTCTCTGTTCCTTTGTTATTACTTGCATGGTTTGGCGTCAGA

>52012_52012_10_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000498502_RPIA_chr2_89049498_ENST00000283646_length(amino acids)=370AA_BP=336
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQ
KNMAMLAQQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYLGPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLMRTD
RLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQAAAAQAAATAAAMT
QSAVKSLKRPLEATFDLGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGVVDTGLFINMAERVYFGMQDG

--------------------------------------------------------------
>52012_52012_11_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000545754_RPIA_chr2_89049498_ENST00000283646_length(transcript)=2501nt_BP=1546nt
GTTGGTACTAAGAAGTGCCTTTCCTGACGTCTCTGCTGCTTGGAACCGCTTCTAGAGCAGTCTCTGCTTTTGCCTTGCTTGCTGCCAGCT
AGACTGTGACGACAGCACATCCACCCTCCACCTCTAGCCCAGACACCCCCATTTCTACTTATAATCAAGAGAAAAGCTCTAAGTATCTGG
CATTGCCCTAGGCTGCTTTAGTGTTAAAAGAAAAGTTTGCTGAAAAAGTAAGATATCTTCTGCCAGGAAATCAAGGAGGAAAAAAAAAAT
CATTTTCTCGATTTTGCTCTAAACTGCTGCATCTGTCTATGCCAAACTAATCAATACCGATTGCACCACCAAACTCCATTGCAAATTCAG
CTGTGAGGAGATTCCCTTTCAGACAACTTTGCTGAAAGCAGCTTGGAAATTCGGTGTCGAAGGGTCTGCCACGTTTTCATGCTTGCATTT
TGGGCTCCAAATTGGCACTGGGAAGGGGTTACTGAGAGCACAAGGCTGATACCAGGCCCTACTTTTAAACGTTCATCTACTTACAATCCT
AGTATTTCTCTAAAAACCAAAACCTCTTTGAATTAACAGTTTCATGCTGTGAATTTCTAGTGGGAGATCTTTTCCTTGATATTGACGACA
CAATTTTCCATGTACTTTTAAAGCAGGGAGTGGGGAAAAGTATTTTGAGGGGACATTTTCATCATCAGTTCAGCTTTTTTTTTTTGGTTG
TTGCTCTTTTTTGGGGGGGTTGGGTTTGTTGGTTTCACTGAAACATTTAACTACCTGTAAAATCTAAACATGGCTGTTAGTGTCACACCA
ATTCGGGACACAAAATGGCTAACACTGGAAGTATGTAGAGAGTTCCAGAGGGGGACTTGCTCACGGCCAGACACGGAATGTAAATTTGCA
CATCCTTCGAAAAGCTGCCAAGTTGAAAATGGACGAGTAATCGCCTGCTTTGATTCATTGAAAGGCCGTTGCTCCAGGGAGAACTGCAAA
TATCTTCATCCACCCCCACATTTAAAAACGCAGTTGGAGATAAATGGACGCAATAACTTGATTCAGCAGAAGAACATGGCCATGTTGGCC
CAGCAAATGCAACTAGCCAATGCCATGATGCCTGGTGCCCCATTACAACCCGTGGTATGTCGAGAGTACCAACGTGGCAATTGCAACCGA
GGAGAAAATGATTGTCGGTTTGCTCATCCTGCTGACAGCACAATGATTGACACCAATGACAACACAGTCACTGTGTGTATGGATTACATC
AAAGGGAGATGCTCTCGGGAAAAGTGCAAATACTTTCATCCCCCTGCACATTTGCAAGCCAAGATCAAGGCTGCCCAATACCAGGTCAAC
CAGGCTGCAGCTGCACAGGCTGCAGCCACCGCAGCTGCCATGGGAATTCCTCAAGCTGTACTTCCCCCATTACCAAAGAGGCCTGCTCTT
GAAAAAACCAACGGTGCCACCGCAGTCTTTAACACTGGTATTTTCCAATACCAACAGGCTCTAGCCAACATGCAGTTACAACAGCATACA
GCATTTCTCCCACCAGGTGTGGTGGACACAGGCCTATTCATCAACATGGCTGAGAGAGTCTACTTTGGGATGCAGGATGGCTCAGTGAAC
ATGAGGGAGAAGCCTTTCTGTTGACCCTGCAAGGAGCAGAGTGTGTTCACCTTGAGTCTCCAGCCCACAGCCAAGGTGGACGTACCTCTC
CAGGAGCCTTTGCCTTAATGTATCTCTGCCTGGACAACTTGTGGTGGGGGGTGGGGGGAAGAGTGGGAGGGGGAGTTAAATCCAGTCTTA
TGAAGTATTGTTATTAAATGTCTTTTTAAAAAGAGAAATATAAACATATATTTTTACTATTAAAATATTCAGTTTTTTAAATGAAGTAGA
ACTTGAGTTCATGTTTTATATGAAATATTTACCAAAAAAAAAAAATGAGGTAAACTGTATTTAAAACCTTTGACTTGAGTCTGCTGGTAA
AGCTTCTGAATATTGAGTTTGCTGAGAAATAAAAATCAAAACTTCTTTAAGCTGGTAAAGTGAGGGGCCCACCAGCAGTGATCTCCTGAT
GCCTTACTGGAAACTTTGTTTACTTGTCTGCTACCCTCTGATTTGTTTTTAGTTAGTTTTTATTGTGAGCACACATAGTACCTAGTTACA
TCTTAAGATCAGGTTTATAAAACTGTGGAGTGGAGCGGTATGGTATGGAATGACTTGGAATGTAAGCTGTCAGGGAGAAAATGTTGTTAC
ACTTTTGCTAAGATCTGGGGGTTTCTTCATATTCCTGCTGTTGGAAGCAGTTGACCAGAAATGCTTGCCAGTACTGCCAAAGCACTGCTG
TGAAATGTGAAGTACTTTGTTTTTTTATTTTTAATGATTTTCTTTTTGTTATTAATATTTTTCTCTGTTCCTTTGTTATTACTTGCATGG

>52012_52012_11_MBNL1-RPIA_MBNL1_chr3_152165562_ENST00000545754_RPIA_chr2_89049498_ENST00000283646_length(amino acids)=284AA_BP=250
MAVSVTPIRDTKWLTLEVCREFQRGTCSRPDTECKFAHPSKSCQVENGRVIACFDSLKGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQ
KNMAMLAQQMQLANAMMPGAPLQPVVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNTVTVCMDYIKGRCSREKCKYFHPPAHLQAKIK
AAQYQVNQAAAAQAAATAAAMGIPQAVLPPLPKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLPPGVVDTGLFINMAERVYFG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MBNL1-RPIA


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MBNL1-RPIA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MBNL1-RPIA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource