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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:MBP-OSBPL1A (FusionGDB2 ID:52076)

Fusion Gene Summary for MBP-OSBPL1A

Fusion gene summary

Fusion gene information	Fusion gene name: MBP-OSBPL1A
	Fusion gene ID: 52076
		Hgene	Tgene
	Gene symbol	MBP	OSBPL1A
	Gene ID	5553	114876
	Gene name	proteoglycan 2, pro eosinophil major basic protein	oxysterol binding protein like 1A
	Synonyms	BMPG\|MBP\|MBP1\|proMBP	ORP-1\|ORP1\|OSBPL1B
	Cytomap	11q12.1	18q11.2
	Type of gene	protein-coding	protein-coding
	Description	bone marrow proteoglycaneosinophil granule major basic proteineosinophil major basic proteinnatural killer cell activatorproteoglycan 2 preproproteinproteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)	oxysterol-binding protein-related protein 1OSBP-related protein 1oxysterol binding protein-like 1Boxysterol-binding protein-related protein 1 variant 1oxysterol-binding protein-related protein 1 variant 2
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000354542, ENST00000355994, ENST00000359645, ENST00000382582, ENST00000397865, ENST00000397866, ENST00000397869, ENST00000397875, ENST00000526111, ENST00000527041, ENST00000578193, ENST00000579129, ENST00000580402, ENST00000397860, ENST00000397863, ENST00000487778, ENST00000528160,	ENST00000357041, ENST00000399443, ENST00000399441, ENST00000582618, ENST00000319481,
Fusion gene scores	* DoF score	26 X 20 X 7=3640	18 X 15 X 10=2700
	# samples	26	19
	** MAII score	log2(26/3640*10)=-3.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(19/2700*10)=-3.82888808360725 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: MBP [Title/Abstract] AND OSBPL1A [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	MBP(74728783)-OSBPL1A(21819348), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across MBP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across OSBPL1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS5.0	N/A	DA198061	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-

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Fusion Gene ORF analysis for MBP-OSBPL1A

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000354542	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000354542	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000355994	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000355994	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000359645	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000359645	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000382582	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000382582	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000397865	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000397865	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000397866	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000397866	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000397869	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000397869	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000397875	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000397875	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000526111	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000526111	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000527041	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000527041	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000578193	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000578193	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000579129	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000579129	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000580402	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-5UTR	ENST00000580402	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000354542	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000354542	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000355994	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000355994	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000359645	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000359645	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000382582	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000382582	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000397865	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000397865	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000397866	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000397866	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000397869	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000397869	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000397875	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000397875	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000526111	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000526111	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000527041	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000527041	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000578193	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000578193	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000579129	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000579129	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000580402	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
5CDS-intron	ENST00000580402	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
Frame-shift	ENST00000355994	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
Frame-shift	ENST00000579129	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
In-frame	ENST00000354542	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
In-frame	ENST00000359645	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
In-frame	ENST00000382582	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
In-frame	ENST00000397865	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
In-frame	ENST00000397866	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
In-frame	ENST00000397869	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
In-frame	ENST00000397875	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
In-frame	ENST00000526111	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
In-frame	ENST00000527041	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
In-frame	ENST00000578193	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
In-frame	ENST00000580402	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-3CDS	ENST00000397860	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-3CDS	ENST00000397863	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-3CDS	ENST00000487778	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-3CDS	ENST00000528160	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-5UTR	ENST00000397860	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-5UTR	ENST00000397860	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-5UTR	ENST00000397863	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-5UTR	ENST00000397863	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-5UTR	ENST00000487778	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-5UTR	ENST00000487778	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-5UTR	ENST00000528160	ENST00000357041	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-5UTR	ENST00000528160	ENST00000399443	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-intron	ENST00000397860	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-intron	ENST00000397860	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-intron	ENST00000397863	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-intron	ENST00000397863	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-intron	ENST00000487778	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-intron	ENST00000487778	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-intron	ENST00000528160	ENST00000399441	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-
intron-intron	ENST00000528160	ENST00000582618	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000382582	MBP	chr18	74728783	-	ENST00000319481	OSBPL1A	chr18	21819348	-	2971	264	78	1835	585
ENST00000397875	MBP	chr18	74728783	-	ENST00000319481	OSBPL1A	chr18	21819348	-	2931	224	38	1795	585
ENST00000397866	MBP	chr18	74728783	-	ENST00000319481	OSBPL1A	chr18	21819348	-	2938	231	45	1802	585
ENST00000397865	MBP	chr18	74728783	-	ENST00000319481	OSBPL1A	chr18	21819348	-	2962	255	69	1826	585
ENST00000527041	MBP	chr18	74728783	-	ENST00000319481	OSBPL1A	chr18	21819348	-	2941	234	48	1805	585
ENST00000359645	MBP	chr18	74728783	-	ENST00000319481	OSBPL1A	chr18	21819348	-	2918	211	25	1782	585
ENST00000397869	MBP	chr18	74728783	-	ENST00000319481	OSBPL1A	chr18	21819348	-	2931	224	38	1795	585
ENST00000354542	MBP	chr18	74728783	-	ENST00000319481	OSBPL1A	chr18	21819348	-	3137	430	124	2001	625
ENST00000526111	MBP	chr18	74728783	-	ENST00000319481	OSBPL1A	chr18	21819348	-	2875	168	48	1739	563
ENST00000580402	MBP	chr18	74728783	-	ENST00000319481	OSBPL1A	chr18	21819348	-	3283	576	0	2147	715
ENST00000578193	MBP	chr18	74728783	-	ENST00000319481	OSBPL1A	chr18	21819348	-	2931	224	38	1795	585

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000382582	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-	0.000410819	0.99958915
ENST00000397875	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-	0.000396897	0.9996031
ENST00000397866	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-	0.000406259	0.9995938
ENST00000397865	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-	0.000407924	0.9995921
ENST00000527041	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-	0.000408276	0.99959177
ENST00000359645	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-	0.00038927	0.9996107
ENST00000397869	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-	0.000396897	0.9996031
ENST00000354542	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-	0.000467048	0.99953294
ENST00000526111	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-	0.000684089	0.999316
ENST00000580402	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-	0.000255547	0.9997445
ENST00000578193	ENST00000319481	MBP	chr18	74728783	-	OSBPL1A	chr18	21819348	-	0.000396897	0.9996031

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Fusion Genomic Features for MBP-OSBPL1A

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MBP-OSBPL1A

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:74728783/chr18:21819348)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000319481

430_463

427

951.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000319481

877_913

427

951.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000357041

430_463

569.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000357041

877_913

569.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000399443

430_463

438.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000399443

877_913

438.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000357041

235_334

569.0

Domain

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000399443

235_334

438.0

Domain

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000319481

469_483

427

951.0

Motif

FFAT

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000357041

469_483

569.0

Motif

FFAT

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000399443

469_483

438.0

Motif

FFAT

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000357041

175_204

569.0

Repeat

Note=ANK 3

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000357041

47_76

569.0

Repeat

Note=ANK 1

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000357041

80_109

569.0

Repeat

Note=ANK 2

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000399443

175_204

438.0

Repeat

Note=ANK 3

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000399443

47_76

438.0

Repeat

Note=ANK 1

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000399443

80_109

438.0

Repeat

Note=ANK 2

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000355994

179_222

192

305.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 1

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000355994

246_256

192

305.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 2

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000359645

179_222

187.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 1

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000359645

246_256

187.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 2

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000382582

179_222

198.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 1

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000382582

246_256

198.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 2

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000397860

179_222

198.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 1

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000397860

246_256

198.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 2

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000397863

179_222

198.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 1

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000397863

246_256

198.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 2

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000397865

179_222

161.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 1

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000397865

246_256

161.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 2

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000397866

179_222

172.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 1

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000397866

246_256

172.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 2

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000580402

179_222

192

305.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 1

Hgene

MBP

chr18:74728783

chr18:21819348

ENST00000580402

246_256

192

305.0

Region

Note=Induces experimental autoimmune encephalomyelitis (EAE) 2

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000319481

235_334

427

951.0

Domain

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000319481

175_204

427

951.0

Repeat

Note=ANK 3

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000319481

47_76

427

951.0

Repeat

Note=ANK 1

Tgene

OSBPL1A

chr18:74728783

chr18:21819348

ENST00000319481

80_109

427

951.0

Repeat

Note=ANK 2

Top

Fusion Gene Sequence for MBP-OSBPL1A

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>52076_52076_1_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000354542_OSBPL1A_chr18_21819348_ENST00000319481_length(transcript)=3137nt_BP=430nt
AGATGCGAACCAGAACAATGGGACCTCCTCTCAGGACACAGCGGTGACTGACTCCAAGCGCACAGCGGACCCGAAGAATGCCTGGCAGGA
TGCCCACCCAGCTGACCCAGGGAGCCGCCCCCACTTGATCCGCCTCTTTTCCCGAGATGCCCCGGGGAGGGAGGACAACACCTTCAAAGA
CAGGCCCTCTGAGTCCGACGAGCTCCAGACCATCCAAGAAGACAGTGCAGCCACCTCCGAGAGCCTGGATGTGATGGCGTCACAGAAGAG
ACCCTCCCAGAGGCACGGATCCAAGTACCTGGCCACAGCAAGTACCATGGACCATGCCAGGCATGGCTTCCTCCCAAGGCACAGAGACAC
GGGCATCCTTGACTCCATCGGGCGCTTCTTTGGCGGTGACAGGGGTGCGCCCAAGCGGGGCTCTGGCAAGGTGAGGAATTTTAAATTGGA
ACAAGAGCAAGAAAAAAACAAAATCTTGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTGAAAGG
CTCTCCACCCGCCAGCATCCTTAGCGAGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTGGAAGC
AGTGACAGCACGCTCCTTTGAAGAGGAAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGCGGAGA
TGCTCTCTCCAATGGCATCAAGAAACACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATCCTCAG
AAAATGTATTGGAATGGAACTATCCAAGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAATACAT
GGAGCATACTTACCTCATCCACAAGGCCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCTGCTGT
TGCTTCTCAGTGGGAACGGACTGGAAAACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTTAGACT
CATCTCCGAACAGGTCAGCCATCACCCACCAATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCTATCTA
TCCCAAACTGAAATTCTGGGGGAAGAGTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCATATAC
ATGGACAAATCCCACCTGCTGTGTGCATAATATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAACCACAA
GACTGGGGACAAATGTGTGTTGAATTTTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGATAAAAG
CAAAAAGAAGCTCTGTGCCCTCTATGGGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAAAATGA
TAAGAAAAATACAGAAGAGAAGAAGAACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAAAGTGT
ATTCATTATCCCTGGAAGCGTTCTTCTATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTTGCAAT
GGTTTTGAATGAAGTAGACAAAGACATGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAAAATGG
AGAGATAGATCAAGCTAGTGAAGAAAAAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTG
GAAGACGAGGTGGTTCCATCAAGGTCCTAATCCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAATTACTT
CAATTTGCCTGACATTTATTAAAATGCATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAATTTTTT
TCCCTTGGTTTCTACTTATCTTTTAAAAAAAAAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTATAAGG
CGATATTGGTGATGAAAGTCTTAGGAAAAATGCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTAAGAGA
ACACTGCTGGGGAATATGCTTTTTATGGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGAACTAT
ATAGTAATCCCAAATCAAGTTATTTTGAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAACTCTC
CTCCTATACAATGTTTATTCTCAGATATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAATCCTC
CCAATGTTACCCCTTCCATCTTCCAAGAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGAATTAA
ACTGGAAAAGTATTTCATTTACTTAGTGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTACATTT
GAACTGAAAATATGTATAAAATCTAGCAATTCACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACCTTGTT
AAATGCTTCCACTTCCAGTGGCAAATGCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTTGTGCA
TTTCAAGTTTGCAAAGTACCTGTGTACTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACATTCATC
TTAAATCTTATAGTATTTATCCACCCAAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTAATTGC

>52076_52076_1_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000354542_OSBPL1A_chr18_21819348_ENST00000319481_length(amino acids)=625AA_BP=102
MIRLFSRDAPGREDNTFKDRPSESDELQTIQEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFG
GDRGAPKRGSGKVRNFKLEQEQEKNKILSEALETLATEHHELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGE
HLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASS
LSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVE
AEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKW
TECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMES

--------------------------------------------------------------
>52076_52076_2_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000359645_OSBPL1A_chr18_21819348_ENST00000319481_length(transcript)=2918nt_BP=211nt
AGACAGTGCAGCCACCTCCGAGAGCCTGGATGTGATGGCGTCACAGAAGAGACCCTCCCAGAGGCACGGATCCAAGTACCTGGCCACAGC
AAGTACCATGGACCATGCCAGGCATGGCTTCCTCCCAAGGCACAGAGACACGGGCATCCTTGACTCCATCGGGCGCTTCTTTGGCGGTGA
CAGGGGTGCGCCCAAGCGGGGCTCTGGCAAGGTGAGGAATTTTAAATTGGAACAAGAGCAAGAAAAAAACAAAATCTTGTCAGAAGCACT
GGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTGAAAGGCTCTCCACCCGCCAGCATCCTTAGCGAGGACGAGTTCTA
TGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTGGAAGCAGTGACAGCACGCTCCTTTGAAGAGGAAGGAGAGCATTT
GGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGCGGAGATGCTCTCTCCAATGGCATCAAGAAACACAGAACAAGTTT
GCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATCCTCAGAAAATGTATTGGAATGGAACTATCCAAGATCACGATGCC
AGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAATACATGGAGCATACTTACCTCATCCACAAGGCCAGTTCACTCTC
TGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCTGCTGTTGCTTCTCAGTGGGAACGGACTGGAAAACCTTTCAACCC
ACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTTAGACTCATCTCCGAACAGGTCAGCCATCACCCACCAATCAGTGC
ATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCTATCTATCCCAAACTGAAATTCTGGGGGAAGAGTGTAGAAGCAGA
ACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCATATACATGGACAAATCCCACCTGCTGTGTGCATAATATCATTGT
GGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAACCACAAGACTGGGGACAAATGTGTGTTGAATTTTAAGCCATGTGG
CCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGATAAAAGCAAAAAGAAGCTCTGTGCCCTCTATGGGAAGTGGACTGA
ATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAAAATGATAAGAAAAATACAGAAGAGAAGAAGAACAGCAAACAGAT
GAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAAAGTGTATTCATTATCCCTGGAAGCGTTCTTCTATGGCGAATAGC
CCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTTGCAATGGTTTTGAATGAAGTAGACAAAGACATGGAGAGTGTGAT
TCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAAAATGGAGAGATAGATCAAGCTAGTGAAGAAAAAAAACGACTTGA
GGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTGGAAGACGAGGTGGTTCCATCAAGGTCCTAATCCCTACAA
TGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAATTACTTCAATTTGCCTGACATTTATTAAAATGCATACAAGTCAGG
GTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAATTTTTTTCCCTTGGTTTCTACTTATCTTTTAAAAAAAAAAATGAA
AAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTATAAGGCGATATTGGTGATGAAAGTCTTAGGAAAAATGCATAATT
TTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTAAGAGAACACTGCTGGGGAATATGCTTTTTATGGTTGCTGTTGCC
ATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGAACTATATAGTAATCCCAAATCAAGTTATTTTGAATATTTTTATG
CTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAACTCTCCTCCTATACAATGTTTATTCTCAGATATAGAGGTTATGT
CATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAATCCTCCCAATGTTACCCCTTCCATCTTCCAAGAAGAAAAAAAAT
GCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGAATTAAACTGGAAAAGTATTTCATTTACTTAGTGCTCTGAATTTA
CTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTACATTTGAACTGAAAATATGTATAAAATCTAGCAATTCACAAAAA
TGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACCTTGTTAAATGCTTCCACTTCCAGTGGCAAATGCCACTAGGGAAA
GTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTTGTGCATTTCAAGTTTGCAAAGTACCTGTGTACTTAAAATATGTG
TGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACATTCATCTTAAATCTTATAGTATTTATCCACCCAAACCCCAGACTG
AGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTAATTGCTGTCTTGAAGTTAACAAGTGTTATAATGAAATAATCTAC

>52076_52076_2_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000359645_OSBPL1A_chr18_21819348_ENST00000319481_length(amino acids)=585AA_BP=62
MDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKVRNFKLEQEQEKNKILSEALETLATEHH
ELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRN
DFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYEL
VRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQY
GNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDE
MPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARK

--------------------------------------------------------------
>52076_52076_3_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000382582_OSBPL1A_chr18_21819348_ENST00000319481_length(transcript)=2971nt_BP=264nt
AACACCTTCAAAGACAGGCCCTCTGAGTCCGACGAGCTCCAGACCATCCAAGAAGACAGTGCAGCCACCTCCGAGAGCCTGGATGTGATG
GCGTCACAGAAGAGACCCTCCCAGAGGCACGGATCCAAGTACCTGGCCACAGCAAGTACCATGGACCATGCCAGGCATGGCTTCCTCCCA
AGGCACAGAGACACGGGCATCCTTGACTCCATCGGGCGCTTCTTTGGCGGTGACAGGGGTGCGCCCAAGCGGGGCTCTGGCAAGGTGAGG
AATTTTAAATTGGAACAAGAGCAAGAAAAAAACAAAATCTTGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAG
TCTCTGGTGAAAGGCTCTCCACCCGCCAGCATCCTTAGCGAGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTG
AGTAGATTGGAAGCAGTGACAGCACGCTCCTTTGAAGAGGAAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGAC
TGTGGTGGCGGAGATGCTCTCTCCAATGGCATCAAGAAACACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATC
TGGAGCATCCTCAGAAAATGTATTGGAATGGAACTATCCAAGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGC
CTAACTGAATACATGGAGCATACTTACCTCATCCACAAGGCCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTT
GCTGTATCTGCTGTTGCTTCTCAGTGGGAACGGACTGGAAAACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGAC
CTTGGATTTAGACTCATCTCCGAACAGGTCAGCCATCACCCACCAATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTT
CATGGCTCTATCTATCCCAAACTGAAATTCTGGGGGAAGAGTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACAC
AATGAGGCATATACATGGACAAATCCCACCTGCTGTGTGCATAATATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAA
ATTATAAACCACAAGACTGGGGACAAATGTGTGTTGAATTTTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTAC
ATTCAAGATAAAAGCAAAAAGAAGCTCTGTGCCCTCTATGGGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCT
TACAAAAAAAATGATAAGAAAAATACAGAAGAGAAGAAGAACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCG
GATTCTGAAAGTGTATTCATTATCCCTGGAAGCGTTCTTCTATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTT
ACTAGTTTTGCAATGGTTTTGAATGAAGTAGACAAAGACATGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGA
GCCATGGAAAATGGAGAGATAGATCAAGCTAGTGAAGAAAAAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAG
TCAGAAGAGGACTGGAAGACGAGGTGGTTCCATCAAGGTCCTAATCCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGG
GACAGAAATTACTTCAATTTGCCTGACATTTATTAAAATGCATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATG
TTTTTAAATTTTTTTCCCTTGGTTTCTACTTATCTTTTAAAAAAAAAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAA
AGCAGGGTATAAGGCGATATTGGTGATGAAAGTCTTAGGAAAAATGCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTAT
ATAGAGGTAAGAGAACACTGCTGGGGAATATGCTTTTTATGGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAG
CTTTATGGAACTATATAGTAATCCCAAATCAAGTTATTTTGAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACA
TATTTAGAACTCTCCTCCTATACAATGTTTATTCTCAGATATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTAT
TCATACTAATCCTCCCAATGTTACCCCTTCCATCTTCCAAGAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAA
TTCTAAAGAATTAAACTGGAAAAGTATTTCATTTACTTAGTGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGG
TTAAGTTTACATTTGAACTGAAAATATGTATAAAATCTAGCAATTCACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAA
TGACAAACCTTGTTAAATGCTTCCACTTCCAGTGGCAAATGCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAA
GGAGGCCTTGTGCATTTCAAGTTTGCAAAGTACCTGTGTACTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATT
GGGGCACATTCATCTTAAATCTTATAGTATTTATCCACCCAAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCC
GTGATTTTAATTGCTGTCTTGAAGTTAACAAGTGTTATAATGAAATAATCTACCTGATGCTAAATAAAGGCTTTAGAATGTTCCCCAAAA

>52076_52076_3_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000382582_OSBPL1A_chr18_21819348_ENST00000319481_length(amino acids)=585AA_BP=62
MDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKVRNFKLEQEQEKNKILSEALETLATEHH
ELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRN
DFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYEL
VRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQY
GNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDE
MPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARK

--------------------------------------------------------------
>52076_52076_4_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000397865_OSBPL1A_chr18_21819348_ENST00000319481_length(transcript)=2962nt_BP=255nt
AAAGACAGGCCCTCTGAGTCCGACGAGCTCCAGACCATCCAAGAAGACAGTGCAGCCACCTCCGAGAGCCTGGATGTGATGGCGTCACAG
AAGAGACCCTCCCAGAGGCACGGATCCAAGTACCTGGCCACAGCAAGTACCATGGACCATGCCAGGCATGGCTTCCTCCCAAGGCACAGA
GACACGGGCATCCTTGACTCCATCGGGCGCTTCTTTGGCGGTGACAGGGGTGCGCCCAAGCGGGGCTCTGGCAAGGTGAGGAATTTTAAA
TTGGAACAAGAGCAAGAAAAAAACAAAATCTTGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTG
AAAGGCTCTCCACCCGCCAGCATCCTTAGCGAGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTG
GAAGCAGTGACAGCACGCTCCTTTGAAGAGGAAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGC
GGAGATGCTCTCTCCAATGGCATCAAGAAACACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATC
CTCAGAAAATGTATTGGAATGGAACTATCCAAGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAA
TACATGGAGCATACTTACCTCATCCACAAGGCCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCT
GCTGTTGCTTCTCAGTGGGAACGGACTGGAAAACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTT
AGACTCATCTCCGAACAGGTCAGCCATCACCCACCAATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCT
ATCTATCCCAAACTGAAATTCTGGGGGAAGAGTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCA
TATACATGGACAAATCCCACCTGCTGTGTGCATAATATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAAC
CACAAGACTGGGGACAAATGTGTGTTGAATTTTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGAT
AAAAGCAAAAAGAAGCTCTGTGCCCTCTATGGGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAA
AATGATAAGAAAAATACAGAAGAGAAGAAGAACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAA
AGTGTATTCATTATCCCTGGAAGCGTTCTTCTATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTT
GCAATGGTTTTGAATGAAGTAGACAAAGACATGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAA
AATGGAGAGATAGATCAAGCTAGTGAAGAAAAAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAG
GACTGGAAGACGAGGTGGTTCCATCAAGGTCCTAATCCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAAT
TACTTCAATTTGCCTGACATTTATTAAAATGCATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAAT
TTTTTTCCCTTGGTTTCTACTTATCTTTTAAAAAAAAAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTA
TAAGGCGATATTGGTGATGAAAGTCTTAGGAAAAATGCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTA
AGAGAACACTGCTGGGGAATATGCTTTTTATGGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGA
ACTATATAGTAATCCCAAATCAAGTTATTTTGAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAA
CTCTCCTCCTATACAATGTTTATTCTCAGATATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAA
TCCTCCCAATGTTACCCCTTCCATCTTCCAAGAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGA
ATTAAACTGGAAAAGTATTTCATTTACTTAGTGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTA
CATTTGAACTGAAAATATGTATAAAATCTAGCAATTCACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACC
TTGTTAAATGCTTCCACTTCCAGTGGCAAATGCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTT
GTGCATTTCAAGTTTGCAAAGTACCTGTGTACTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACAT
TCATCTTAAATCTTATAGTATTTATCCACCCAAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTA

>52076_52076_4_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000397865_OSBPL1A_chr18_21819348_ENST00000319481_length(amino acids)=585AA_BP=62
MDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKVRNFKLEQEQEKNKILSEALETLATEHH
ELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRN
DFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYEL
VRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQY
GNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDE
MPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARK

--------------------------------------------------------------
>52076_52076_5_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000397866_OSBPL1A_chr18_21819348_ENST00000319481_length(transcript)=2938nt_BP=231nt
GAGCTCCAGACCATCCAAGAAGACAGTGCAGCCACCTCCGAGAGCCTGGATGTGATGGCGTCACAGAAGAGACCCTCCCAGAGGCACGGA
TCCAAGTACCTGGCCACAGCAAGTACCATGGACCATGCCAGGCATGGCTTCCTCCCAAGGCACAGAGACACGGGCATCCTTGACTCCATC
GGGCGCTTCTTTGGCGGTGACAGGGGTGCGCCCAAGCGGGGCTCTGGCAAGGTGAGGAATTTTAAATTGGAACAAGAGCAAGAAAAAAAC
AAAATCTTGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTGAAAGGCTCTCCACCCGCCAGCATC
CTTAGCGAGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTGGAAGCAGTGACAGCACGCTCCTTT
GAAGAGGAAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGCGGAGATGCTCTCTCCAATGGCATC
AAGAAACACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATCCTCAGAAAATGTATTGGAATGGAA
CTATCCAAGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAATACATGGAGCATACTTACCTCATC
CACAAGGCCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCTGCTGTTGCTTCTCAGTGGGAACGG
ACTGGAAAACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTTAGACTCATCTCCGAACAGGTCAGC
CATCACCCACCAATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCTATCTATCCCAAACTGAAATTCTGG
GGGAAGAGTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCATATACATGGACAAATCCCACCTGC
TGTGTGCATAATATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAACCACAAGACTGGGGACAAATGTGTG
TTGAATTTTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGATAAAAGCAAAAAGAAGCTCTGTGCC
CTCTATGGGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAAAATGATAAGAAAAATACAGAAGAG
AAGAAGAACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAAAGTGTATTCATTATCCCTGGAAGC
GTTCTTCTATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTTGCAATGGTTTTGAATGAAGTAGAC
AAAGACATGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAAAATGGAGAGATAGATCAAGCTAGT
GAAGAAAAAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTGGAAGACGAGGTGGTTCCAT
CAAGGTCCTAATCCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAATTACTTCAATTTGCCTGACATTTAT
TAAAATGCATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAATTTTTTTCCCTTGGTTTCTACTTAT
CTTTTAAAAAAAAAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTATAAGGCGATATTGGTGATGAAAGT
CTTAGGAAAAATGCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTAAGAGAACACTGCTGGGGAATATGC
TTTTTATGGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGAACTATATAGTAATCCCAAATCAAG
TTATTTTGAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAACTCTCCTCCTATACAATGTTTATT
CTCAGATATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAATCCTCCCAATGTTACCCCTTCCAT
CTTCCAAGAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGAATTAAACTGGAAAAGTATTTCATT
TACTTAGTGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTACATTTGAACTGAAAATATGTATAA
AATCTAGCAATTCACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACCTTGTTAAATGCTTCCACTTCCAGT
GGCAAATGCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTTGTGCATTTCAAGTTTGCAAAGTAC
CTGTGTACTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACATTCATCTTAAATCTTATAGTATTTA
TCCACCCAAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTAATTGCTGTCTTGAAGTTAACAAGT

>52076_52076_5_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000397866_OSBPL1A_chr18_21819348_ENST00000319481_length(amino acids)=585AA_BP=62
MDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKVRNFKLEQEQEKNKILSEALETLATEHH
ELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRN
DFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYEL
VRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQY
GNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDE
MPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARK

--------------------------------------------------------------
>52076_52076_6_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000397869_OSBPL1A_chr18_21819348_ENST00000319481_length(transcript)=2931nt_BP=224nt
AGACCATCCAAGAAGACAGTGCAGCCACCTCCGAGAGCCTGGATGTGATGGCGTCACAGAAGAGACCCTCCCAGAGGCACGGATCCAAGT
ACCTGGCCACAGCAAGTACCATGGACCATGCCAGGCATGGCTTCCTCCCAAGGCACAGAGACACGGGCATCCTTGACTCCATCGGGCGCT
TCTTTGGCGGTGACAGGGGTGCGCCCAAGCGGGGCTCTGGCAAGGTGAGGAATTTTAAATTGGAACAAGAGCAAGAAAAAAACAAAATCT
TGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTGAAAGGCTCTCCACCCGCCAGCATCCTTAGCG
AGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTGGAAGCAGTGACAGCACGCTCCTTTGAAGAGG
AAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGCGGAGATGCTCTCTCCAATGGCATCAAGAAAC
ACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATCCTCAGAAAATGTATTGGAATGGAACTATCCA
AGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAATACATGGAGCATACTTACCTCATCCACAAGG
CCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCTGCTGTTGCTTCTCAGTGGGAACGGACTGGAA
AACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTTAGACTCATCTCCGAACAGGTCAGCCATCACC
CACCAATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCTATCTATCCCAAACTGAAATTCTGGGGGAAGA
GTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCATATACATGGACAAATCCCACCTGCTGTGTGC
ATAATATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAACCACAAGACTGGGGACAAATGTGTGTTGAATT
TTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGATAAAAGCAAAAAGAAGCTCTGTGCCCTCTATG
GGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAAAATGATAAGAAAAATACAGAAGAGAAGAAGA
ACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAAAGTGTATTCATTATCCCTGGAAGCGTTCTTC
TATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTTGCAATGGTTTTGAATGAAGTAGACAAAGACA
TGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAAAATGGAGAGATAGATCAAGCTAGTGAAGAAA
AAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTGGAAGACGAGGTGGTTCCATCAAGGTC
CTAATCCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAATTACTTCAATTTGCCTGACATTTATTAAAATG
CATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAATTTTTTTCCCTTGGTTTCTACTTATCTTTTAA
AAAAAAAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTATAAGGCGATATTGGTGATGAAAGTCTTAGGA
AAAATGCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTAAGAGAACACTGCTGGGGAATATGCTTTTTAT
GGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGAACTATATAGTAATCCCAAATCAAGTTATTTT
GAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAACTCTCCTCCTATACAATGTTTATTCTCAGAT
ATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAATCCTCCCAATGTTACCCCTTCCATCTTCCAA
GAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGAATTAAACTGGAAAAGTATTTCATTTACTTAG
TGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTACATTTGAACTGAAAATATGTATAAAATCTAG
CAATTCACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACCTTGTTAAATGCTTCCACTTCCAGTGGCAAAT
GCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTTGTGCATTTCAAGTTTGCAAAGTACCTGTGTA
CTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACATTCATCTTAAATCTTATAGTATTTATCCACCC
AAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTAATTGCTGTCTTGAAGTTAACAAGTGTTATAA

>52076_52076_6_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000397869_OSBPL1A_chr18_21819348_ENST00000319481_length(amino acids)=585AA_BP=62
MDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKVRNFKLEQEQEKNKILSEALETLATEHH
ELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRN
DFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYEL
VRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQY
GNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDE
MPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARK

--------------------------------------------------------------
>52076_52076_7_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000397875_OSBPL1A_chr18_21819348_ENST00000319481_length(transcript)=2931nt_BP=224nt
AGACCATCCAAGAAGACAGTGCAGCCACCTCCGAGAGCCTGGATGTGATGGCGTCACAGAAGAGACCCTCCCAGAGGCACGGATCCAAGT
ACCTGGCCACAGCAAGTACCATGGACCATGCCAGGCATGGCTTCCTCCCAAGGCACAGAGACACGGGCATCCTTGACTCCATCGGGCGCT
TCTTTGGCGGTGACAGGGGTGCGCCCAAGCGGGGCTCTGGCAAGGTGAGGAATTTTAAATTGGAACAAGAGCAAGAAAAAAACAAAATCT
TGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTGAAAGGCTCTCCACCCGCCAGCATCCTTAGCG
AGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTGGAAGCAGTGACAGCACGCTCCTTTGAAGAGG
AAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGCGGAGATGCTCTCTCCAATGGCATCAAGAAAC
ACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATCCTCAGAAAATGTATTGGAATGGAACTATCCA
AGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAATACATGGAGCATACTTACCTCATCCACAAGG
CCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCTGCTGTTGCTTCTCAGTGGGAACGGACTGGAA
AACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTTAGACTCATCTCCGAACAGGTCAGCCATCACC
CACCAATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCTATCTATCCCAAACTGAAATTCTGGGGGAAGA
GTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCATATACATGGACAAATCCCACCTGCTGTGTGC
ATAATATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAACCACAAGACTGGGGACAAATGTGTGTTGAATT
TTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGATAAAAGCAAAAAGAAGCTCTGTGCCCTCTATG
GGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAAAATGATAAGAAAAATACAGAAGAGAAGAAGA
ACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAAAGTGTATTCATTATCCCTGGAAGCGTTCTTC
TATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTTGCAATGGTTTTGAATGAAGTAGACAAAGACA
TGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAAAATGGAGAGATAGATCAAGCTAGTGAAGAAA
AAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTGGAAGACGAGGTGGTTCCATCAAGGTC
CTAATCCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAATTACTTCAATTTGCCTGACATTTATTAAAATG
CATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAATTTTTTTCCCTTGGTTTCTACTTATCTTTTAA
AAAAAAAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTATAAGGCGATATTGGTGATGAAAGTCTTAGGA
AAAATGCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTAAGAGAACACTGCTGGGGAATATGCTTTTTAT
GGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGAACTATATAGTAATCCCAAATCAAGTTATTTT
GAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAACTCTCCTCCTATACAATGTTTATTCTCAGAT
ATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAATCCTCCCAATGTTACCCCTTCCATCTTCCAA
GAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGAATTAAACTGGAAAAGTATTTCATTTACTTAG
TGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTACATTTGAACTGAAAATATGTATAAAATCTAG
CAATTCACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACCTTGTTAAATGCTTCCACTTCCAGTGGCAAAT
GCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTTGTGCATTTCAAGTTTGCAAAGTACCTGTGTA
CTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACATTCATCTTAAATCTTATAGTATTTATCCACCC
AAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTAATTGCTGTCTTGAAGTTAACAAGTGTTATAA

>52076_52076_7_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000397875_OSBPL1A_chr18_21819348_ENST00000319481_length(amino acids)=585AA_BP=62
MDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKVRNFKLEQEQEKNKILSEALETLATEHH
ELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRN
DFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYEL
VRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQY
GNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDE
MPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARK

--------------------------------------------------------------
>52076_52076_8_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000526111_OSBPL1A_chr18_21819348_ENST00000319481_length(transcript)=2875nt_BP=168nt
GACGAGCTCCAGACCATCCAAGAAGACAGTGCAGCCACCTCCGAGAGCCTGGATGTGATGGCGTCACAGAAGAGACCCTCCCAGAGGCAC
AGAGACACGGGCATCCTTGACTCCATCGGGCGCTTCTTTGGCGGTGACAGGGGTGCGCCCAAGCGGGGCTCTGGCAAGGTGAGGAATTTT
AAATTGGAACAAGAGCAAGAAAAAAACAAAATCTTGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTG
GTGAAAGGCTCTCCACCCGCCAGCATCCTTAGCGAGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGA
TTGGAAGCAGTGACAGCACGCTCCTTTGAAGAGGAAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGT
GGCGGAGATGCTCTCTCCAATGGCATCAAGAAACACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGC
ATCCTCAGAAAATGTATTGGAATGGAACTATCCAAGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACT
GAATACATGGAGCATACTTACCTCATCCACAAGGCCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTA
TCTGCTGTTGCTTCTCAGTGGGAACGGACTGGAAAACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGA
TTTAGACTCATCTCCGAACAGGTCAGCCATCACCCACCAATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGC
TCTATCTATCCCAAACTGAAATTCTGGGGGAAGAGTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAG
GCATATACATGGACAAATCCCACCTGCTGTGTGCATAATATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATA
AACCACAAGACTGGGGACAAATGTGTGTTGAATTTTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAA
GATAAAAGCAAAAAGAAGCTCTGTGCCCTCTATGGGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAA
AAAAATGATAAGAAAAATACAGAAGAGAAGAAGAACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCT
GAAAGTGTATTCATTATCCCTGGAAGCGTTCTTCTATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGT
TTTGCAATGGTTTTGAATGAAGTAGACAAAGACATGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATG
GAAAATGGAGAGATAGATCAAGCTAGTGAAGAAAAAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAA
GAGGACTGGAAGACGAGGTGGTTCCATCAAGGTCCTAATCCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGA
AATTACTTCAATTTGCCTGACATTTATTAAAATGCATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTA
AATTTTTTTCCCTTGGTTTCTACTTATCTTTTAAAAAAAAAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGG
GTATAAGGCGATATTGGTGATGAAAGTCTTAGGAAAAATGCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAG
GTAAGAGAACACTGCTGGGGAATATGCTTTTTATGGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTAT
GGAACTATATAGTAATCCCAAATCAAGTTATTTTGAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTA
GAACTCTCCTCCTATACAATGTTTATTCTCAGATATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATAC
TAATCCTCCCAATGTTACCCCTTCCATCTTCCAAGAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAA
AGAATTAAACTGGAAAAGTATTTCATTTACTTAGTGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGT
TTACATTTGAACTGAAAATATGTATAAAATCTAGCAATTCACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAA
ACCTTGTTAAATGCTTCCACTTCCAGTGGCAAATGCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGC
CTTGTGCATTTCAAGTTTGCAAAGTACCTGTGTACTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCA
CATTCATCTTAAATCTTATAGTATTTATCCACCCAAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATT

>52076_52076_8_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000526111_OSBPL1A_chr18_21819348_ENST00000319481_length(amino acids)=563AA_BP=40
MDVMASQKRPSQRHRDTGILDSIGRFFGGDRGAPKRGSGKVRNFKLEQEQEKNKILSEALETLATEHHELEQSLVKGSPPASILSEDEFY
DALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMP
VIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISA
FHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCG
LFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIA
PRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYN

--------------------------------------------------------------
>52076_52076_9_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000527041_OSBPL1A_chr18_21819348_ENST00000319481_length(transcript)=2941nt_BP=234nt
GACGAGCTCCAGACCATCCAAGAAGACAGTGCAGCCACCTCCGAGAGCCTGGATGTGATGGCGTCACAGAAGAGACCCTCCCAGAGGCAC
GGATCCAAGTACCTGGCCACAGCAAGTACCATGGACCATGCCAGGCATGGCTTCCTCCCAAGGCACAGAGACACGGGCATCCTTGACTCC
ATCGGGCGCTTCTTTGGCGGTGACAGGGGTGCGCCCAAGCGGGGCTCTGGCAAGGTGAGGAATTTTAAATTGGAACAAGAGCAAGAAAAA
AACAAAATCTTGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTGAAAGGCTCTCCACCCGCCAGC
ATCCTTAGCGAGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTGGAAGCAGTGACAGCACGCTCC
TTTGAAGAGGAAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGCGGAGATGCTCTCTCCAATGGC
ATCAAGAAACACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATCCTCAGAAAATGTATTGGAATG
GAACTATCCAAGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAATACATGGAGCATACTTACCTC
ATCCACAAGGCCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCTGCTGTTGCTTCTCAGTGGGAA
CGGACTGGAAAACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTTAGACTCATCTCCGAACAGGTC
AGCCATCACCCACCAATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCTATCTATCCCAAACTGAAATTC
TGGGGGAAGAGTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCATATACATGGACAAATCCCACC
TGCTGTGTGCATAATATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAACCACAAGACTGGGGACAAATGT
GTGTTGAATTTTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGATAAAAGCAAAAAGAAGCTCTGT
GCCCTCTATGGGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAAAATGATAAGAAAAATACAGAA
GAGAAGAAGAACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAAAGTGTATTCATTATCCCTGGA
AGCGTTCTTCTATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTTGCAATGGTTTTGAATGAAGTA
GACAAAGACATGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAAAATGGAGAGATAGATCAAGCT
AGTGAAGAAAAAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTGGAAGACGAGGTGGTTC
CATCAAGGTCCTAATCCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAATTACTTCAATTTGCCTGACATT
TATTAAAATGCATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAATTTTTTTCCCTTGGTTTCTACT
TATCTTTTAAAAAAAAAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTATAAGGCGATATTGGTGATGAA
AGTCTTAGGAAAAATGCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTAAGAGAACACTGCTGGGGAATA
TGCTTTTTATGGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGAACTATATAGTAATCCCAAATC
AAGTTATTTTGAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAACTCTCCTCCTATACAATGTTT
ATTCTCAGATATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAATCCTCCCAATGTTACCCCTTC
CATCTTCCAAGAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGAATTAAACTGGAAAAGTATTTC
ATTTACTTAGTGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTACATTTGAACTGAAAATATGTA
TAAAATCTAGCAATTCACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACCTTGTTAAATGCTTCCACTTCC
AGTGGCAAATGCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTTGTGCATTTCAAGTTTGCAAAG
TACCTGTGTACTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACATTCATCTTAAATCTTATAGTAT
TTATCCACCCAAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTAATTGCTGTCTTGAAGTTAACA

>52076_52076_9_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000527041_OSBPL1A_chr18_21819348_ENST00000319481_length(amino acids)=585AA_BP=62
MDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKVRNFKLEQEQEKNKILSEALETLATEHH
ELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRN
DFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYEL
VRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQY
GNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDE
MPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARK

--------------------------------------------------------------
>52076_52076_10_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000578193_OSBPL1A_chr18_21819348_ENST00000319481_length(transcript)=2931nt_BP=224nt
AGACCATCCAAGAAGACAGTGCAGCCACCTCCGAGAGCCTGGATGTGATGGCGTCACAGAAGAGACCCTCCCAGAGGCACGGATCCAAGT
ACCTGGCCACAGCAAGTACCATGGACCATGCCAGGCATGGCTTCCTCCCAAGGCACAGAGACACGGGCATCCTTGACTCCATCGGGCGCT
TCTTTGGCGGTGACAGGGGTGCGCCCAAGCGGGGCTCTGGCAAGGTGAGGAATTTTAAATTGGAACAAGAGCAAGAAAAAAACAAAATCT
TGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTGAAAGGCTCTCCACCCGCCAGCATCCTTAGCG
AGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTGGAAGCAGTGACAGCACGCTCCTTTGAAGAGG
AAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGCGGAGATGCTCTCTCCAATGGCATCAAGAAAC
ACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATCCTCAGAAAATGTATTGGAATGGAACTATCCA
AGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAATACATGGAGCATACTTACCTCATCCACAAGG
CCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCTGCTGTTGCTTCTCAGTGGGAACGGACTGGAA
AACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTTAGACTCATCTCCGAACAGGTCAGCCATCACC
CACCAATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCTATCTATCCCAAACTGAAATTCTGGGGGAAGA
GTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCATATACATGGACAAATCCCACCTGCTGTGTGC
ATAATATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAACCACAAGACTGGGGACAAATGTGTGTTGAATT
TTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGATAAAAGCAAAAAGAAGCTCTGTGCCCTCTATG
GGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAAAATGATAAGAAAAATACAGAAGAGAAGAAGA
ACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAAAGTGTATTCATTATCCCTGGAAGCGTTCTTC
TATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTTGCAATGGTTTTGAATGAAGTAGACAAAGACA
TGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAAAATGGAGAGATAGATCAAGCTAGTGAAGAAA
AAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTGGAAGACGAGGTGGTTCCATCAAGGTC
CTAATCCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAATTACTTCAATTTGCCTGACATTTATTAAAATG
CATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAATTTTTTTCCCTTGGTTTCTACTTATCTTTTAA
AAAAAAAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTATAAGGCGATATTGGTGATGAAAGTCTTAGGA
AAAATGCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTAAGAGAACACTGCTGGGGAATATGCTTTTTAT
GGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGAACTATATAGTAATCCCAAATCAAGTTATTTT
GAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAACTCTCCTCCTATACAATGTTTATTCTCAGAT
ATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAATCCTCCCAATGTTACCCCTTCCATCTTCCAA
GAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGAATTAAACTGGAAAAGTATTTCATTTACTTAG
TGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTACATTTGAACTGAAAATATGTATAAAATCTAG
CAATTCACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACCTTGTTAAATGCTTCCACTTCCAGTGGCAAAT
GCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTTGTGCATTTCAAGTTTGCAAAGTACCTGTGTA
CTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACATTCATCTTAAATCTTATAGTATTTATCCACCC
AAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTAATTGCTGTCTTGAAGTTAACAAGTGTTATAA

>52076_52076_10_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000578193_OSBPL1A_chr18_21819348_ENST00000319481_length(amino acids)=585AA_BP=62
MDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKVRNFKLEQEQEKNKILSEALETLATEHH
ELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRN
DFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYEL
VRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQY
GNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDE
MPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARK

--------------------------------------------------------------
>52076_52076_11_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000580402_OSBPL1A_chr18_21819348_ENST00000319481_length(transcript)=3283nt_BP=576nt
ATGGGAAACCACGCAGGCAAACGAGAATTAAATGCCGAGAAGGCCAGTACGAATAGTGAAACTAACAGAGGAGAATCTGAAAAAAAGAGA
AACCTGGGTGAACTTTCACGGACAACCTCAGAGGACAACGAAGTGTTCGGAGAGGCAGATGCGAACCAGAACAATGGGACCTCCTCTCAG
GACACAGCGGTGACTGACTCCAAGCGCACAGCGGACCCGAAGAATGCCTGGCAGGATGCCCACCCAGCTGACCCAGGGAGCCGCCCCCAC
TTGATCCGCCTCTTTTCCCGAGATGCCCCGGGGAGGGAGGACAACACCTTCAAAGACAGGCCCTCTGAGTCCGACGAGCTCCAGACCATC
CAAGAAGACAGTGCAGCCACCTCCGAGAGCCTGGATGTGATGGCGTCACAGAAGAGACCCTCCCAGAGGCACGGATCCAAGTACCTGGCC
ACAGCAAGTACCATGGACCATGCCAGGCATGGCTTCCTCCCAAGGCACAGAGACACGGGCATCCTTGACTCCATCGGGCGCTTCTTTGGC
GGTGACAGGGGTGCGCCCAAGCGGGGCTCTGGCAAGGTGAGGAATTTTAAATTGGAACAAGAGCAAGAAAAAAACAAAATCTTGTCAGAA
GCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTGAAAGGCTCTCCACCCGCCAGCATCCTTAGCGAGGACGAG
TTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTGGAAGCAGTGACAGCACGCTCCTTTGAAGAGGAAGGAGAG
CATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGCGGAGATGCTCTCTCCAATGGCATCAAGAAACACAGAACA
AGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATCCTCAGAAAATGTATTGGAATGGAACTATCCAAGATCACG
ATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAATACATGGAGCATACTTACCTCATCCACAAGGCCAGTTCA
CTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCTGCTGTTGCTTCTCAGTGGGAACGGACTGGAAAACCTTTC
AACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTTAGACTCATCTCCGAACAGGTCAGCCATCACCCACCAATC
AGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCTATCTATCCCAAACTGAAATTCTGGGGGAAGAGTGTAGAA
GCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCATATACATGGACAAATCCCACCTGCTGTGTGCATAATATC
ATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAACCACAAGACTGGGGACAAATGTGTGTTGAATTTTAAGCCA
TGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGATAAAAGCAAAAAGAAGCTCTGTGCCCTCTATGGGAAGTGG
ACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAAAATGATAAGAAAAATACAGAAGAGAAGAAGAACAGCAAA
CAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAAAGTGTATTCATTATCCCTGGAAGCGTTCTTCTATGGCGA
ATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTTGCAATGGTTTTGAATGAAGTAGACAAAGACATGGAGAGT
GTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAAAATGGAGAGATAGATCAAGCTAGTGAAGAAAAAAAACGA
CTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTGGAAGACGAGGTGGTTCCATCAAGGTCCTAATCCC
TACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAATTACTTCAATTTGCCTGACATTTATTAAAATGCATACAAG
TCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAATTTTTTTCCCTTGGTTTCTACTTATCTTTTAAAAAAAAAA
ATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTATAAGGCGATATTGGTGATGAAAGTCTTAGGAAAAATGCA
TAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTAAGAGAACACTGCTGGGGAATATGCTTTTTATGGTTGCTG
TTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGAACTATATAGTAATCCCAAATCAAGTTATTTTGAATATTT
TTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAACTCTCCTCCTATACAATGTTTATTCTCAGATATAGAGGT
TATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAATCCTCCCAATGTTACCCCTTCCATCTTCCAAGAAGAAAA
AAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGAATTAAACTGGAAAAGTATTTCATTTACTTAGTGCTCTGA
ATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTACATTTGAACTGAAAATATGTATAAAATCTAGCAATTCAC
AAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACCTTGTTAAATGCTTCCACTTCCAGTGGCAAATGCCACTAG
GGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTTGTGCATTTCAAGTTTGCAAAGTACCTGTGTACTTAAAAT
ATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACATTCATCTTAAATCTTATAGTATTTATCCACCCAAACCCCA
GACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTAATTGCTGTCTTGAAGTTAACAAGTGTTATAATGAAATAA

>52076_52076_11_MBP-OSBPL1A_MBP_chr18_74728783_ENST00000580402_OSBPL1A_chr18_21819348_ENST00000319481_length(amino acids)=715AA_BP=192
MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQDTAVTDSKRTADPKNAWQDAHPADPGSRPH
LIRLFSRDAPGREDNTFKDRPSESDELQTIQEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFG
GDRGAPKRGSGKVRNFKLEQEQEKNKILSEALETLATEHHELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGE
HLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASS
LSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVE
AEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKW
TECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMES

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for MBP-OSBPL1A

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Tgene	OSBPL1A	chr18:74728783	chr18:21819348	ENST00000399443		0	14	1_237	0	438.0	RAB7A

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Tgene	OSBPL1A	chr18:74728783	chr18:21819348	ENST00000319481		14	28	1_237	427.0	951.0	RAB7A
Tgene	OSBPL1A	chr18:74728783	chr18:21819348	ENST00000357041		2	16	1_237	45.0	569.0	RAB7A

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for MBP-OSBPL1A

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for MBP-OSBPL1A

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source