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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MCFD2-SRBD1 (FusionGDB2 ID:52193)

Fusion Gene Summary for MCFD2-SRBD1

check button Fusion gene summary
Fusion gene informationFusion gene name: MCFD2-SRBD1
Fusion gene ID: 52193
HgeneTgene
Gene symbol

MCFD2

SRBD1

Gene ID

90411

55133

Gene namemultiple coagulation factor deficiency 2, ER cargo receptor complex subunitS1 RNA binding domain 1
SynonymsF5F8D|F5F8D2|LMAN1IP|SDNSF-
Cytomap

2p21

2p21

Type of geneprotein-codingprotein-coding
Descriptionmultiple coagulation factor deficiency protein 2multiple coagulation factor deficiency 2neural stem cell-derived neuronal survival proteinS1 RNA-binding domain-containing protein 1H_NH0576F01.1WUGSC:H_NH0576F01.1
Modification date2020031320200313
UniProtAcc

Q8NI22

.
Ensembl transtripts involved in fusion geneENST00000319466, ENST00000409105, 
ENST00000409147, ENST00000409207, 
ENST00000409218, ENST00000409800, 
ENST00000409913, ENST00000409973, 
ENST00000444761, ENST00000493804, 
ENST00000490133, ENST00000263736, 
ENST00000535761, 
Fusion gene scores* DoF score5 X 7 X 4=1403 X 3 X 3=27
# samples 64
** MAII scorelog2(6/140*10)=-1.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/27*10)=0.567040592723894
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: MCFD2 [Title/Abstract] AND SRBD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMCFD2(47134949)-SRBD1(45647033), # samples:3
Anticipated loss of major functional domain due to fusion event.MCFD2-SRBD1 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
MCFD2-SRBD1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
MCFD2-SRBD1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MCFD2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SRBD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AR-A24H-01AMCFD2chr2

47134949

-SRBD1chr2

45647033

-
ChimerDB4BRCATCGA-AR-A24H-01AMCFD2chr2

47136162

-SRBD1chr2

45715470

-


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Fusion Gene ORF analysis for MCFD2-SRBD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000319466ENST00000490133MCFD2chr2

47134949

-SRBD1chr2

45647033

-
5CDS-5UTRENST00000409105ENST00000490133MCFD2chr2

47134949

-SRBD1chr2

45647033

-
5CDS-5UTRENST00000409147ENST00000490133MCFD2chr2

47134949

-SRBD1chr2

45647033

-
5CDS-5UTRENST00000409207ENST00000490133MCFD2chr2

47134949

-SRBD1chr2

45647033

-
5CDS-5UTRENST00000409218ENST00000490133MCFD2chr2

47134949

-SRBD1chr2

45647033

-
5CDS-5UTRENST00000409800ENST00000490133MCFD2chr2

47134949

-SRBD1chr2

45647033

-
5CDS-5UTRENST00000409913ENST00000490133MCFD2chr2

47134949

-SRBD1chr2

45647033

-
5CDS-5UTRENST00000409973ENST00000490133MCFD2chr2

47134949

-SRBD1chr2

45647033

-
5CDS-5UTRENST00000444761ENST00000490133MCFD2chr2

47134949

-SRBD1chr2

45647033

-
5CDS-intronENST00000319466ENST00000490133MCFD2chr2

47136162

-SRBD1chr2

45715470

-
5CDS-intronENST00000409105ENST00000490133MCFD2chr2

47136162

-SRBD1chr2

45715470

-
5CDS-intronENST00000409207ENST00000490133MCFD2chr2

47136162

-SRBD1chr2

45715470

-
5CDS-intronENST00000409218ENST00000490133MCFD2chr2

47136162

-SRBD1chr2

45715470

-
5CDS-intronENST00000409973ENST00000490133MCFD2chr2

47136162

-SRBD1chr2

45715470

-
Frame-shiftENST00000319466ENST00000263736MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000319466ENST00000263736MCFD2chr2

47136162

-SRBD1chr2

45715470

-
Frame-shiftENST00000319466ENST00000535761MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000319466ENST00000535761MCFD2chr2

47136162

-SRBD1chr2

45715470

-
Frame-shiftENST00000409147ENST00000263736MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000409147ENST00000535761MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000409218ENST00000263736MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000409218ENST00000263736MCFD2chr2

47136162

-SRBD1chr2

45715470

-
Frame-shiftENST00000409218ENST00000535761MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000409218ENST00000535761MCFD2chr2

47136162

-SRBD1chr2

45715470

-
Frame-shiftENST00000409800ENST00000263736MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000409800ENST00000535761MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000409913ENST00000263736MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000409913ENST00000535761MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000409973ENST00000263736MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000409973ENST00000263736MCFD2chr2

47136162

-SRBD1chr2

45715470

-
Frame-shiftENST00000409973ENST00000535761MCFD2chr2

47134949

-SRBD1chr2

45647033

-
Frame-shiftENST00000409973ENST00000535761MCFD2chr2

47136162

-SRBD1chr2

45715470

-
In-frameENST00000409105ENST00000263736MCFD2chr2

47134949

-SRBD1chr2

45647033

-
In-frameENST00000409105ENST00000263736MCFD2chr2

47136162

-SRBD1chr2

45715470

-
In-frameENST00000409105ENST00000535761MCFD2chr2

47134949

-SRBD1chr2

45647033

-
In-frameENST00000409105ENST00000535761MCFD2chr2

47136162

-SRBD1chr2

45715470

-
In-frameENST00000409207ENST00000263736MCFD2chr2

47134949

-SRBD1chr2

45647033

-
In-frameENST00000409207ENST00000263736MCFD2chr2

47136162

-SRBD1chr2

45715470

-
In-frameENST00000409207ENST00000535761MCFD2chr2

47134949

-SRBD1chr2

45647033

-
In-frameENST00000409207ENST00000535761MCFD2chr2

47136162

-SRBD1chr2

45715470

-
In-frameENST00000444761ENST00000263736MCFD2chr2

47134949

-SRBD1chr2

45647033

-
In-frameENST00000444761ENST00000535761MCFD2chr2

47134949

-SRBD1chr2

45647033

-
intron-3CDSENST00000409147ENST00000263736MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-3CDSENST00000409147ENST00000535761MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-3CDSENST00000409800ENST00000263736MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-3CDSENST00000409800ENST00000535761MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-3CDSENST00000409913ENST00000263736MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-3CDSENST00000409913ENST00000535761MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-3CDSENST00000444761ENST00000263736MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-3CDSENST00000444761ENST00000535761MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-3CDSENST00000493804ENST00000263736MCFD2chr2

47134949

-SRBD1chr2

45647033

-
intron-3CDSENST00000493804ENST00000263736MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-3CDSENST00000493804ENST00000535761MCFD2chr2

47134949

-SRBD1chr2

45647033

-
intron-3CDSENST00000493804ENST00000535761MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-5UTRENST00000493804ENST00000490133MCFD2chr2

47134949

-SRBD1chr2

45647033

-
intron-intronENST00000409147ENST00000490133MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-intronENST00000409800ENST00000490133MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-intronENST00000409913ENST00000490133MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-intronENST00000444761ENST00000490133MCFD2chr2

47136162

-SRBD1chr2

45715470

-
intron-intronENST00000493804ENST00000490133MCFD2chr2

47136162

-SRBD1chr2

45715470

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000444761MCFD2chr247134949-ENST00000263736SRBD1chr245647033-2013444511382443
ENST00000444761MCFD2chr247134949-ENST00000535761SRBD1chr245647033-1600444511382443
ENST00000409105MCFD2chr247134949-ENST00000263736SRBD1chr245647033-2058489991427442
ENST00000409105MCFD2chr247134949-ENST00000535761SRBD1chr245647033-1645489991427442
ENST00000409207MCFD2chr247134949-ENST00000263736SRBD1chr245647033-2045476801414444
ENST00000409207MCFD2chr247134949-ENST00000535761SRBD1chr245647033-1632476801414444
ENST00000409105MCFD2chr247136162-ENST00000263736SRBD1chr245715470-2073329991442447
ENST00000409105MCFD2chr247136162-ENST00000535761SRBD1chr245715470-1660329991442447
ENST00000409207MCFD2chr247136162-ENST00000263736SRBD1chr245715470-2060316801429449
ENST00000409207MCFD2chr247136162-ENST00000535761SRBD1chr245715470-1647316801429449

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000444761ENST00000263736MCFD2chr247134949-SRBD1chr245647033-0.0025291340.99747086
ENST00000444761ENST00000535761MCFD2chr247134949-SRBD1chr245647033-0.0053057240.9946943
ENST00000409105ENST00000263736MCFD2chr247134949-SRBD1chr245647033-0.0012968210.9987031
ENST00000409105ENST00000535761MCFD2chr247134949-SRBD1chr245647033-0.0030776070.9969223
ENST00000409207ENST00000263736MCFD2chr247134949-SRBD1chr245647033-0.0015822480.99841774
ENST00000409207ENST00000535761MCFD2chr247134949-SRBD1chr245647033-0.0033320020.99666804
ENST00000409105ENST00000263736MCFD2chr247136162-SRBD1chr245715470-0.0016553830.99834466
ENST00000409105ENST00000535761MCFD2chr247136162-SRBD1chr245715470-0.004889590.99511045
ENST00000409207ENST00000263736MCFD2chr247136162-SRBD1chr245715470-0.0021185580.9978815
ENST00000409207ENST00000535761MCFD2chr247136162-SRBD1chr245715470-0.0050560780.9949439

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Fusion Genomic Features for MCFD2-SRBD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MCFD2-SRBD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:47134949/chr2:45647033)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MCFD2

Q8NI22

.
FUNCTION: The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. Plays a role in the secretion of coagulation factors. {ECO:0000269|PubMed:12717434}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMCFD2chr2:47134949chr2:45647033ENST00000319466-3481_92103147.0Calcium bindingNote=1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409105-4581_92103147.0Calcium bindingNote=1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409207-3481_92103147.0Calcium bindingNote=1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409218-3481_92103147.0Calcium bindingNote=1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409973-4581_92103147.0Calcium bindingNote=1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000319466-3468_103103147.0DomainEF-hand 1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409105-4568_103103147.0DomainEF-hand 1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409207-3468_103103147.0DomainEF-hand 1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409218-3468_103103147.0DomainEF-hand 1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409973-4568_103103147.0DomainEF-hand 1
TgeneSRBD1chr2:47134949chr2:45647033ENST000002637361521919_992683996.0DomainS1 motif
TgeneSRBD1chr2:47136162chr2:45715470ENST000002637361321919_992624996.0DomainS1 motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMCFD2chr2:47134949chr2:45647033ENST00000319466-34129_140103147.0Calcium bindingNote=2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409105-45129_140103147.0Calcium bindingNote=2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409147-23129_1405195.0Calcium bindingNote=2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409147-2381_925195.0Calcium bindingNote=1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409207-34129_140103147.0Calcium bindingNote=2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409218-34129_140103147.0Calcium bindingNote=2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409800-23129_1405195.0Calcium bindingNote=2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409800-2381_925195.0Calcium bindingNote=1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409913-23129_1405195.0Calcium bindingNote=2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409913-2381_925195.0Calcium bindingNote=1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409973-45129_140103147.0Calcium bindingNote=2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000444761-23129_14084128.0Calcium bindingNote=2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000444761-2381_9284128.0Calcium bindingNote=1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000319466-24129_14049147.0Calcium bindingNote=2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000319466-2481_9249147.0Calcium bindingNote=1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409105-35129_14049147.0Calcium bindingNote=2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409105-3581_9249147.0Calcium bindingNote=1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409147-13129_140095.0Calcium bindingNote=2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409147-1381_92095.0Calcium bindingNote=1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409207-24129_14049147.0Calcium bindingNote=2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409207-2481_9249147.0Calcium bindingNote=1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409218-24129_14049147.0Calcium bindingNote=2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409218-2481_9249147.0Calcium bindingNote=1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409800-13129_140095.0Calcium bindingNote=2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409800-1381_92095.0Calcium bindingNote=1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409913-13129_140095.0Calcium bindingNote=2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409913-1381_92095.0Calcium bindingNote=1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409973-35129_14049147.0Calcium bindingNote=2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409973-3581_9249147.0Calcium bindingNote=1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000444761-13129_1400128.0Calcium bindingNote=2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000444761-1381_920128.0Calcium bindingNote=1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000319466-34116_146103147.0DomainEF-hand 2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409105-45116_146103147.0DomainEF-hand 2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409147-23116_1465195.0DomainEF-hand 2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409147-2368_1035195.0DomainEF-hand 1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409207-34116_146103147.0DomainEF-hand 2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409218-34116_146103147.0DomainEF-hand 2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409800-23116_1465195.0DomainEF-hand 2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409800-2368_1035195.0DomainEF-hand 1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409913-23116_1465195.0DomainEF-hand 2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409913-2368_1035195.0DomainEF-hand 1
HgeneMCFD2chr2:47134949chr2:45647033ENST00000409973-45116_146103147.0DomainEF-hand 2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000444761-23116_14684128.0DomainEF-hand 2
HgeneMCFD2chr2:47134949chr2:45647033ENST00000444761-2368_10384128.0DomainEF-hand 1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000319466-24116_14649147.0DomainEF-hand 2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000319466-2468_10349147.0DomainEF-hand 1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409105-35116_14649147.0DomainEF-hand 2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409105-3568_10349147.0DomainEF-hand 1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409147-13116_146095.0DomainEF-hand 2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409147-1368_103095.0DomainEF-hand 1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409207-24116_14649147.0DomainEF-hand 2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409207-2468_10349147.0DomainEF-hand 1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409218-24116_14649147.0DomainEF-hand 2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409218-2468_10349147.0DomainEF-hand 1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409800-13116_146095.0DomainEF-hand 2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409800-1368_103095.0DomainEF-hand 1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409913-13116_146095.0DomainEF-hand 2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409913-1368_103095.0DomainEF-hand 1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409973-35116_14649147.0DomainEF-hand 2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000409973-3568_10349147.0DomainEF-hand 1
HgeneMCFD2chr2:47136162chr2:45715470ENST00000444761-13116_1460128.0DomainEF-hand 2
HgeneMCFD2chr2:47136162chr2:45715470ENST00000444761-1368_1030128.0DomainEF-hand 1
TgeneSRBD1chr2:47134949chr2:45647033ENST000002637361521258_288683996.0Coiled coilOntology_term=ECO:0000255
TgeneSRBD1chr2:47136162chr2:45715470ENST000002637361321258_288624996.0Coiled coilOntology_term=ECO:0000255
TgeneSRBD1chr2:47134949chr2:45647033ENST00000263736152180_83683996.0Compositional biasNote=Poly-Val
TgeneSRBD1chr2:47136162chr2:45715470ENST00000263736132180_83624996.0Compositional biasNote=Poly-Val


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Fusion Gene Sequence for MCFD2-SRBD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>52193_52193_1_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000409105_SRBD1_chr2_45647033_ENST00000263736_length(transcript)=2058nt_BP=489nt
ACGGGGGCTGGTGAGGCTCACGTTGGAGGGCTTCGCGTCTGCTTCGGAGACCGTAAGGCTGTCATCAGCTGTGGACGGGAGCCTTCTGAA
GGGAAGCACTTGGGAGCCTGCAGGACGAATACCTACACCAGACTTGGAATTGAAAAGACCTCACTGGAGAAAGAGACATTTGATATATTG
ATGACCATGAGATCCCTGCTCAGAACCCCCTTCCTGTGTGGCCTGCTCTGGGCCTTTTGTGCCCCAGGCGCCAGGGCTGAGGAGCCTGCA
GCCAGCTTCTCCCAACCCGGCAGCATGGGCCTGGATAAGAACACAGTGCACGACCAAGAGCATATCATGGAGCATCTAGAAGGTGTCATC
AACAAACCAGAGGCGGAGATGTCGCCACAAGAATTGCAGCTCCATTACTTCAAAATGCATGATTATGATGGCAATAATTTGCTTGATGGC
TTAGAACTCTCCACAGCCATCACTCATGTCCATAAGGAGCATGACGTATCCCAGACTTTACTCAAGGCAACACTGGACAGTGTTGTAGAA
GAATGTGTCAGCTTTGTGGGAGTGGATATTAACATCTGTTCAGAAGTTTTGTTAAGGCATATTGCAGGACTCAATGCCAACAGGGCCAAA
AATATTATTGAATGGCGAGAGAAAAATGGACCCTTTATCAACCGAGAACAGCTGAAGAAAGTGAAAGGGCTGGGCCCAAAATCCTTCCAA
CAGTGTGCTGGCTTCATCAGAATCAACCAGGATTATATCCGAACGTTTTGCAGTCAGCAAACTGAAACTTCAGGCCAAATTCAAGGAGTT
GCTGTGACATCTTCAGCAGACGTTGAGGTCACAAATGAGAAGCAGGGCAAAAAGAAGAGCAAAACTGCAGTGAATGTTTTACTGAAGCCA
AATCCTTTGGACCAAACTTGTATTCATCCAGAATCATATGACATAGCAATGAGGTTTTTGTCATCCATTGGAGGGACACTGTATGAGGTT
GGAAAGCCTGAAATGCAACAAAAAATAAATTCATTCCTTGAAAAGGAAGGAATGGAGAAAATTGCAGAAAGATTGCAAACAACAGTACAC
ACCTTACAGGTCATCATAGATGGTCTCAGCCAGCCTGAAAGCTTTGACTTTCGAACAGATTTTGATAAACCTGATTTCAAGAGAAGCATA
GTATGCCTGGAAGATCTGCAGATTGGGACAGTTCTTACAGGCAAAGTTGAGAATGCCACTCTCTTTGGAATTTTTGTGGATATAGGAGTG
GGGAAATCTGGGCTGATTCCCATACGAAATGTAACAGAAGCAAAACTTTCAAAAACAAAGAAGAGAAGAAGCCTTGGACTGGGCCCCGGA
GAAAGAGTGGAAGTCCAAGTACTCAACATTGACATCCCCCGATCTAGGATTACTCTGGACCTCATTCGGGTGTTATGAGTATCCCACGAA
GGCCAGACGCTGATTTTATTTTCTCATTTCCACAGATTGACAAGGATAAGTCAGTTGTTTGTAAACTCTAGGTAGCAGATGAGAAATAAT
TCACTTAATATCAGAAATATTTTCCAAACACTTTCCTTTATTTTTTCTTCTGAATAAATAGAAAACCAACAGTTTGATTTCCTTTTCCCT
TAAAGGAAACAACTAATACACATTCTTATATGGCTTTATGTAGTAATAGTTTTCTGACTAAAATTTTGTTTTTTATTTTTTGTAATTTAT
CTTTAACTCCTTTTGCATTTTGTATAACAGATTGCTTAACTTCTACTTGCCAACATCTGCCTTGCTGGACTTGTATGGGATTGTCTTCTT
GATTTGAATTGTACCGTCTTTGTTGACACAGTAGGGCTGGGCAGTGTTTAATCCTTCCATTTTATAGATTTTTTTTTAATCAGGCCTTTT
GGACTTCATTCATAATTTTGCAATAATCTCTTTTCCCTTGTCATGCAAGCCAAAAATATACCAGTAAAACAGATTCTGACGTGTTTGTAG

>52193_52193_1_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000409105_SRBD1_chr2_45647033_ENST00000263736_length(amino acids)=442AA_BP=130
MGACRTNTYTRLGIEKTSLEKETFDILMTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQEHIMEHLEGVINKP
EAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKNII
EWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQTETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNVLLKPNPL
DQTCIHPESYDIAMRFLSSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTDFDKPDFKRSIVCL

--------------------------------------------------------------
>52193_52193_2_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000409105_SRBD1_chr2_45647033_ENST00000535761_length(transcript)=1645nt_BP=489nt
ACGGGGGCTGGTGAGGCTCACGTTGGAGGGCTTCGCGTCTGCTTCGGAGACCGTAAGGCTGTCATCAGCTGTGGACGGGAGCCTTCTGAA
GGGAAGCACTTGGGAGCCTGCAGGACGAATACCTACACCAGACTTGGAATTGAAAAGACCTCACTGGAGAAAGAGACATTTGATATATTG
ATGACCATGAGATCCCTGCTCAGAACCCCCTTCCTGTGTGGCCTGCTCTGGGCCTTTTGTGCCCCAGGCGCCAGGGCTGAGGAGCCTGCA
GCCAGCTTCTCCCAACCCGGCAGCATGGGCCTGGATAAGAACACAGTGCACGACCAAGAGCATATCATGGAGCATCTAGAAGGTGTCATC
AACAAACCAGAGGCGGAGATGTCGCCACAAGAATTGCAGCTCCATTACTTCAAAATGCATGATTATGATGGCAATAATTTGCTTGATGGC
TTAGAACTCTCCACAGCCATCACTCATGTCCATAAGGAGCATGACGTATCCCAGACTTTACTCAAGGCAACACTGGACAGTGTTGTAGAA
GAATGTGTCAGCTTTGTGGGAGTGGATATTAACATCTGTTCAGAAGTTTTGTTAAGGCATATTGCAGGACTCAATGCCAACAGGGCCAAA
AATATTATTGAATGGCGAGAGAAAAATGGACCCTTTATCAACCGAGAACAGCTGAAGAAAGTGAAAGGGCTGGGCCCAAAATCCTTCCAA
CAGTGTGCTGGCTTCATCAGAATCAACCAGGATTATATCCGAACGTTTTGCAGTCAGCAAACTGAAACTTCAGGCCAAATTCAAGGAGTT
GCTGTGACATCTTCAGCAGACGTTGAGGTCACAAATGAGAAGCAGGGCAAAAAGAAGAGCAAAACTGCAGTGAATGTTTTACTGAAGCCA
AATCCTTTGGACCAAACTTGTATTCATCCAGAATCATATGACATAGCAATGAGGTTTTTGTCATCCATTGGAGGGACACTGTATGAGGTT
GGAAAGCCTGAAATGCAACAAAAAATAAATTCATTCCTTGAAAAGGAAGGAATGGAGAAAATTGCAGAAAGATTGCAAACAACAGTACAC
ACCTTACAGGTCATCATAGATGGTCTCAGCCAGCCTGAAAGCTTTGACTTTCGAACAGATTTTGATAAACCTGATTTCAAGAGAAGCATA
GTATGCCTGGAAGATCTGCAGATTGGGACAGTTCTTACAGGCAAAGTTGAGAATGCCACTCTCTTTGGAATTTTTGTGGATATAGGAGTG
GGGAAATCTGGGCTGATTCCCATACGAAATGTAACAGAAGCAAAACTTTCAAAAACAAAGAAGAGAAGAAGCCTTGGACTGGGCCCCGGA
GAAAGAGTGGAAGTCCAAGTACTCAACATTGACATCCCCCGATCTAGGATTACTCTGGACCTCATTCGGGTGTTATGAGTATCCCACGAA
GGCCAGACGCTGATTTTATTTTCTCATTTCCACAGATTGACAAGGATAAGTCAGTTGTTTGTAAACTCTAGGTAGCAGATGAGAAATAAT
TCACTTAATATCAGAAATATTTTCCAAACACTTTCCTTTATTTTTTCTTCTGAATAAATAGAAAACCAACAGTTTGATTTCCTTTTCCCT

>52193_52193_2_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000409105_SRBD1_chr2_45647033_ENST00000535761_length(amino acids)=442AA_BP=130
MGACRTNTYTRLGIEKTSLEKETFDILMTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQEHIMEHLEGVINKP
EAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKNII
EWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQTETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNVLLKPNPL
DQTCIHPESYDIAMRFLSSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTDFDKPDFKRSIVCL

--------------------------------------------------------------
>52193_52193_3_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000409207_SRBD1_chr2_45647033_ENST00000263736_length(transcript)=2045nt_BP=476nt
TACTCACCGGTGTCCGGAAAGGTGAACGCTGCGCTCGGGCTGCCTCGCCTGTTACCTCCGCCGCCGGGCATGCTCAGCGTCTGCAGCTGC
CGGACCAGCTCCGGCATGCGGTCCCAGTGGCCCTCGGCGCGGCAGCGCTCCAGCTCGCTCTCCACCTTCAGATATTGATGACCATGAGAT
CCCTGCTCAGAACCCCCTTCCTGTGTGGCCTGCTCTGGGCCTTTTGTGCCCCAGGCGCCAGGGCTGAGGAGCCTGCAGCCAGCTTCTCCC
AACCCGGCAGCATGGGCCTGGATAAGAACACAGTGCACGACCAAGAGCATATCATGGAGCATCTAGAAGGTGTCATCAACAAACCAGAGG
CGGAGATGTCGCCACAAGAATTGCAGCTCCATTACTTCAAAATGCATGATTATGATGGCAATAATTTGCTTGATGGCTTAGAACTCTCCA
CAGCCATCACTCATGTCCATAAGGAGCATGACGTATCCCAGACTTTACTCAAGGCAACACTGGACAGTGTTGTAGAAGAATGTGTCAGCT
TTGTGGGAGTGGATATTAACATCTGTTCAGAAGTTTTGTTAAGGCATATTGCAGGACTCAATGCCAACAGGGCCAAAAATATTATTGAAT
GGCGAGAGAAAAATGGACCCTTTATCAACCGAGAACAGCTGAAGAAAGTGAAAGGGCTGGGCCCAAAATCCTTCCAACAGTGTGCTGGCT
TCATCAGAATCAACCAGGATTATATCCGAACGTTTTGCAGTCAGCAAACTGAAACTTCAGGCCAAATTCAAGGAGTTGCTGTGACATCTT
CAGCAGACGTTGAGGTCACAAATGAGAAGCAGGGCAAAAAGAAGAGCAAAACTGCAGTGAATGTTTTACTGAAGCCAAATCCTTTGGACC
AAACTTGTATTCATCCAGAATCATATGACATAGCAATGAGGTTTTTGTCATCCATTGGAGGGACACTGTATGAGGTTGGAAAGCCTGAAA
TGCAACAAAAAATAAATTCATTCCTTGAAAAGGAAGGAATGGAGAAAATTGCAGAAAGATTGCAAACAACAGTACACACCTTACAGGTCA
TCATAGATGGTCTCAGCCAGCCTGAAAGCTTTGACTTTCGAACAGATTTTGATAAACCTGATTTCAAGAGAAGCATAGTATGCCTGGAAG
ATCTGCAGATTGGGACAGTTCTTACAGGCAAAGTTGAGAATGCCACTCTCTTTGGAATTTTTGTGGATATAGGAGTGGGGAAATCTGGGC
TGATTCCCATACGAAATGTAACAGAAGCAAAACTTTCAAAAACAAAGAAGAGAAGAAGCCTTGGACTGGGCCCCGGAGAAAGAGTGGAAG
TCCAAGTACTCAACATTGACATCCCCCGATCTAGGATTACTCTGGACCTCATTCGGGTGTTATGAGTATCCCACGAAGGCCAGACGCTGA
TTTTATTTTCTCATTTCCACAGATTGACAAGGATAAGTCAGTTGTTTGTAAACTCTAGGTAGCAGATGAGAAATAATTCACTTAATATCA
GAAATATTTTCCAAACACTTTCCTTTATTTTTTCTTCTGAATAAATAGAAAACCAACAGTTTGATTTCCTTTTCCCTTAAAGGAAACAAC
TAATACACATTCTTATATGGCTTTATGTAGTAATAGTTTTCTGACTAAAATTTTGTTTTTTATTTTTTGTAATTTATCTTTAACTCCTTT
TGCATTTTGTATAACAGATTGCTTAACTTCTACTTGCCAACATCTGCCTTGCTGGACTTGTATGGGATTGTCTTCTTGATTTGAATTGTA
CCGTCTTTGTTGACACAGTAGGGCTGGGCAGTGTTTAATCCTTCCATTTTATAGATTTTTTTTTAATCAGGCCTTTTGGACTTCATTCAT
AATTTTGCAATAATCTCTTTTCCCTTGTCATGCAAGCCAAAAATATACCAGTAAAACAGATTCTGACGTGTTTGTAGTTATCAAATGAAT

>52193_52193_3_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000409207_SRBD1_chr2_45647033_ENST00000263736_length(amino acids)=444AA_BP=132
MQLPDQLRHAVPVALGAAALQLALHLQILMTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQEHIMEHLEGVIN
KPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKN
IIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQTETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNVLLKPN
PLDQTCIHPESYDIAMRFLSSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTDFDKPDFKRSIV

--------------------------------------------------------------
>52193_52193_4_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000409207_SRBD1_chr2_45647033_ENST00000535761_length(transcript)=1632nt_BP=476nt
TACTCACCGGTGTCCGGAAAGGTGAACGCTGCGCTCGGGCTGCCTCGCCTGTTACCTCCGCCGCCGGGCATGCTCAGCGTCTGCAGCTGC
CGGACCAGCTCCGGCATGCGGTCCCAGTGGCCCTCGGCGCGGCAGCGCTCCAGCTCGCTCTCCACCTTCAGATATTGATGACCATGAGAT
CCCTGCTCAGAACCCCCTTCCTGTGTGGCCTGCTCTGGGCCTTTTGTGCCCCAGGCGCCAGGGCTGAGGAGCCTGCAGCCAGCTTCTCCC
AACCCGGCAGCATGGGCCTGGATAAGAACACAGTGCACGACCAAGAGCATATCATGGAGCATCTAGAAGGTGTCATCAACAAACCAGAGG
CGGAGATGTCGCCACAAGAATTGCAGCTCCATTACTTCAAAATGCATGATTATGATGGCAATAATTTGCTTGATGGCTTAGAACTCTCCA
CAGCCATCACTCATGTCCATAAGGAGCATGACGTATCCCAGACTTTACTCAAGGCAACACTGGACAGTGTTGTAGAAGAATGTGTCAGCT
TTGTGGGAGTGGATATTAACATCTGTTCAGAAGTTTTGTTAAGGCATATTGCAGGACTCAATGCCAACAGGGCCAAAAATATTATTGAAT
GGCGAGAGAAAAATGGACCCTTTATCAACCGAGAACAGCTGAAGAAAGTGAAAGGGCTGGGCCCAAAATCCTTCCAACAGTGTGCTGGCT
TCATCAGAATCAACCAGGATTATATCCGAACGTTTTGCAGTCAGCAAACTGAAACTTCAGGCCAAATTCAAGGAGTTGCTGTGACATCTT
CAGCAGACGTTGAGGTCACAAATGAGAAGCAGGGCAAAAAGAAGAGCAAAACTGCAGTGAATGTTTTACTGAAGCCAAATCCTTTGGACC
AAACTTGTATTCATCCAGAATCATATGACATAGCAATGAGGTTTTTGTCATCCATTGGAGGGACACTGTATGAGGTTGGAAAGCCTGAAA
TGCAACAAAAAATAAATTCATTCCTTGAAAAGGAAGGAATGGAGAAAATTGCAGAAAGATTGCAAACAACAGTACACACCTTACAGGTCA
TCATAGATGGTCTCAGCCAGCCTGAAAGCTTTGACTTTCGAACAGATTTTGATAAACCTGATTTCAAGAGAAGCATAGTATGCCTGGAAG
ATCTGCAGATTGGGACAGTTCTTACAGGCAAAGTTGAGAATGCCACTCTCTTTGGAATTTTTGTGGATATAGGAGTGGGGAAATCTGGGC
TGATTCCCATACGAAATGTAACAGAAGCAAAACTTTCAAAAACAAAGAAGAGAAGAAGCCTTGGACTGGGCCCCGGAGAAAGAGTGGAAG
TCCAAGTACTCAACATTGACATCCCCCGATCTAGGATTACTCTGGACCTCATTCGGGTGTTATGAGTATCCCACGAAGGCCAGACGCTGA
TTTTATTTTCTCATTTCCACAGATTGACAAGGATAAGTCAGTTGTTTGTAAACTCTAGGTAGCAGATGAGAAATAATTCACTTAATATCA
GAAATATTTTCCAAACACTTTCCTTTATTTTTTCTTCTGAATAAATAGAAAACCAACAGTTTGATTTCCTTTTCCCTTAAAGGAAACAAC

>52193_52193_4_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000409207_SRBD1_chr2_45647033_ENST00000535761_length(amino acids)=444AA_BP=132
MQLPDQLRHAVPVALGAAALQLALHLQILMTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQEHIMEHLEGVIN
KPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKN
IIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQTETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNVLLKPN
PLDQTCIHPESYDIAMRFLSSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTDFDKPDFKRSIV

--------------------------------------------------------------
>52193_52193_5_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000444761_SRBD1_chr2_45647033_ENST00000263736_length(transcript)=2013nt_BP=444nt
GCTCTTAAGACTAGCACGGTGGGCTGGCAGGCGCCCGCTGTCGGCCGAGGACTGTCTGGGCGCGCTTCCTGGAGGAGGCGGTGCGTTTCG
CGCGCTCGCTGCCGGCGAGCCAGCCTCTTCCCTTACTCACCGGTGTCCGGAAAGGTGAACGCTGCGCTCGGGCTGCCTCGCCTGTTACCT
CCGCCGCCGGGCATGCTCAGCGTCTGCAGCTGCCGGACCAGCTCCGGCATGCGGTCCCAGTGGCCCTCGGCGCGGCAGCGCTCCAGCTCG
CTCTCCACCTTCAGGCATATCATGGAGCATCTAGAAGGTGTCATCAACAAACCAGAGGCGGAGATGTCGCCACAAGAATTGCAGCTCCAT
TACTTCAAAATGCATGATTATGATGGCAATAATTTGCTTGATGGCTTAGAACTCTCCACAGCCATCACTCATGTCCATAAGGAGCATGAC
GTATCCCAGACTTTACTCAAGGCAACACTGGACAGTGTTGTAGAAGAATGTGTCAGCTTTGTGGGAGTGGATATTAACATCTGTTCAGAA
GTTTTGTTAAGGCATATTGCAGGACTCAATGCCAACAGGGCCAAAAATATTATTGAATGGCGAGAGAAAAATGGACCCTTTATCAACCGA
GAACAGCTGAAGAAAGTGAAAGGGCTGGGCCCAAAATCCTTCCAACAGTGTGCTGGCTTCATCAGAATCAACCAGGATTATATCCGAACG
TTTTGCAGTCAGCAAACTGAAACTTCAGGCCAAATTCAAGGAGTTGCTGTGACATCTTCAGCAGACGTTGAGGTCACAAATGAGAAGCAG
GGCAAAAAGAAGAGCAAAACTGCAGTGAATGTTTTACTGAAGCCAAATCCTTTGGACCAAACTTGTATTCATCCAGAATCATATGACATA
GCAATGAGGTTTTTGTCATCCATTGGAGGGACACTGTATGAGGTTGGAAAGCCTGAAATGCAACAAAAAATAAATTCATTCCTTGAAAAG
GAAGGAATGGAGAAAATTGCAGAAAGATTGCAAACAACAGTACACACCTTACAGGTCATCATAGATGGTCTCAGCCAGCCTGAAAGCTTT
GACTTTCGAACAGATTTTGATAAACCTGATTTCAAGAGAAGCATAGTATGCCTGGAAGATCTGCAGATTGGGACAGTTCTTACAGGCAAA
GTTGAGAATGCCACTCTCTTTGGAATTTTTGTGGATATAGGAGTGGGGAAATCTGGGCTGATTCCCATACGAAATGTAACAGAAGCAAAA
CTTTCAAAAACAAAGAAGAGAAGAAGCCTTGGACTGGGCCCCGGAGAAAGAGTGGAAGTCCAAGTACTCAACATTGACATCCCCCGATCT
AGGATTACTCTGGACCTCATTCGGGTGTTATGAGTATCCCACGAAGGCCAGACGCTGATTTTATTTTCTCATTTCCACAGATTGACAAGG
ATAAGTCAGTTGTTTGTAAACTCTAGGTAGCAGATGAGAAATAATTCACTTAATATCAGAAATATTTTCCAAACACTTTCCTTTATTTTT
TCTTCTGAATAAATAGAAAACCAACAGTTTGATTTCCTTTTCCCTTAAAGGAAACAACTAATACACATTCTTATATGGCTTTATGTAGTA
ATAGTTTTCTGACTAAAATTTTGTTTTTTATTTTTTGTAATTTATCTTTAACTCCTTTTGCATTTTGTATAACAGATTGCTTAACTTCTA
CTTGCCAACATCTGCCTTGCTGGACTTGTATGGGATTGTCTTCTTGATTTGAATTGTACCGTCTTTGTTGACACAGTAGGGCTGGGCAGT
GTTTAATCCTTCCATTTTATAGATTTTTTTTTAATCAGGCCTTTTGGACTTCATTCATAATTTTGCAATAATCTCTTTTCCCTTGTCATG
CAAGCCAAAAATATACCAGTAAAACAGATTCTGACGTGTTTGTAGTTATCAAATGAATGGCTCGAAACACTTCTCAAAAGGATATACGTA

>52193_52193_5_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000444761_SRBD1_chr2_45647033_ENST00000263736_length(amino acids)=443AA_BP=131
MSGRASWRRRCVSRARCRRASLFPYSPVSGKVNAALGLPRLLPPPPGMLSVCSCRTSSGMRSQWPSARQRSSSLSTFRHIMEHLEGVINK
PEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKNI
IEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQTETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNVLLKPNP
LDQTCIHPESYDIAMRFLSSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTDFDKPDFKRSIVC

--------------------------------------------------------------
>52193_52193_6_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000444761_SRBD1_chr2_45647033_ENST00000535761_length(transcript)=1600nt_BP=444nt
GCTCTTAAGACTAGCACGGTGGGCTGGCAGGCGCCCGCTGTCGGCCGAGGACTGTCTGGGCGCGCTTCCTGGAGGAGGCGGTGCGTTTCG
CGCGCTCGCTGCCGGCGAGCCAGCCTCTTCCCTTACTCACCGGTGTCCGGAAAGGTGAACGCTGCGCTCGGGCTGCCTCGCCTGTTACCT
CCGCCGCCGGGCATGCTCAGCGTCTGCAGCTGCCGGACCAGCTCCGGCATGCGGTCCCAGTGGCCCTCGGCGCGGCAGCGCTCCAGCTCG
CTCTCCACCTTCAGGCATATCATGGAGCATCTAGAAGGTGTCATCAACAAACCAGAGGCGGAGATGTCGCCACAAGAATTGCAGCTCCAT
TACTTCAAAATGCATGATTATGATGGCAATAATTTGCTTGATGGCTTAGAACTCTCCACAGCCATCACTCATGTCCATAAGGAGCATGAC
GTATCCCAGACTTTACTCAAGGCAACACTGGACAGTGTTGTAGAAGAATGTGTCAGCTTTGTGGGAGTGGATATTAACATCTGTTCAGAA
GTTTTGTTAAGGCATATTGCAGGACTCAATGCCAACAGGGCCAAAAATATTATTGAATGGCGAGAGAAAAATGGACCCTTTATCAACCGA
GAACAGCTGAAGAAAGTGAAAGGGCTGGGCCCAAAATCCTTCCAACAGTGTGCTGGCTTCATCAGAATCAACCAGGATTATATCCGAACG
TTTTGCAGTCAGCAAACTGAAACTTCAGGCCAAATTCAAGGAGTTGCTGTGACATCTTCAGCAGACGTTGAGGTCACAAATGAGAAGCAG
GGCAAAAAGAAGAGCAAAACTGCAGTGAATGTTTTACTGAAGCCAAATCCTTTGGACCAAACTTGTATTCATCCAGAATCATATGACATA
GCAATGAGGTTTTTGTCATCCATTGGAGGGACACTGTATGAGGTTGGAAAGCCTGAAATGCAACAAAAAATAAATTCATTCCTTGAAAAG
GAAGGAATGGAGAAAATTGCAGAAAGATTGCAAACAACAGTACACACCTTACAGGTCATCATAGATGGTCTCAGCCAGCCTGAAAGCTTT
GACTTTCGAACAGATTTTGATAAACCTGATTTCAAGAGAAGCATAGTATGCCTGGAAGATCTGCAGATTGGGACAGTTCTTACAGGCAAA
GTTGAGAATGCCACTCTCTTTGGAATTTTTGTGGATATAGGAGTGGGGAAATCTGGGCTGATTCCCATACGAAATGTAACAGAAGCAAAA
CTTTCAAAAACAAAGAAGAGAAGAAGCCTTGGACTGGGCCCCGGAGAAAGAGTGGAAGTCCAAGTACTCAACATTGACATCCCCCGATCT
AGGATTACTCTGGACCTCATTCGGGTGTTATGAGTATCCCACGAAGGCCAGACGCTGATTTTATTTTCTCATTTCCACAGATTGACAAGG
ATAAGTCAGTTGTTTGTAAACTCTAGGTAGCAGATGAGAAATAATTCACTTAATATCAGAAATATTTTCCAAACACTTTCCTTTATTTTT

>52193_52193_6_MCFD2-SRBD1_MCFD2_chr2_47134949_ENST00000444761_SRBD1_chr2_45647033_ENST00000535761_length(amino acids)=443AA_BP=131
MSGRASWRRRCVSRARCRRASLFPYSPVSGKVNAALGLPRLLPPPPGMLSVCSCRTSSGMRSQWPSARQRSSSLSTFRHIMEHLEGVINK
PEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANRAKNI
IEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQTETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNVLLKPNP
LDQTCIHPESYDIAMRFLSSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTDFDKPDFKRSIVC

--------------------------------------------------------------
>52193_52193_7_MCFD2-SRBD1_MCFD2_chr2_47136162_ENST00000409105_SRBD1_chr2_45715470_ENST00000263736_length(transcript)=2073nt_BP=329nt
ACGGGGGCTGGTGAGGCTCACGTTGGAGGGCTTCGCGTCTGCTTCGGAGACCGTAAGGCTGTCATCAGCTGTGGACGGGAGCCTTCTGAA
GGGAAGCACTTGGGAGCCTGCAGGACGAATACCTACACCAGACTTGGAATTGAAAAGACCTCACTGGAGAAAGAGACATTTGATATATTG
ATGACCATGAGATCCCTGCTCAGAACCCCCTTCCTGTGTGGCCTGCTCTGGGCCTTTTGTGCCCCAGGCGCCAGGGCTGAGGAGCCTGCA
GCCAGCTTCTCCCAACCCGGCAGCATGGGCCTGGATAAGAACACAGTGCACGACCAAGATATCGTCAGTGAAGCAGGAGCATCAATCTAC
AGTGTCAGCCCTGAAGCTAACAAAGAGATGCCAGGGCTGGACCCTAATTTGAGAAGTGCAGTTTCCATAGCAAGGCGTGTACAAGATCCA
TTAGCTGAGCTAGTGAAAATTGAGCCAAAGCACATTGGAGTTGGAATGTATCAGCATGACGTATCCCAGACTTTACTCAAGGCAACACTG
GACAGTGTTGTAGAAGAATGTGTCAGCTTTGTGGGAGTGGATATTAACATCTGTTCAGAAGTTTTGTTAAGGCATATTGCAGGACTCAAT
GCCAACAGGGCCAAAAATATTATTGAATGGCGAGAGAAAAATGGACCCTTTATCAACCGAGAACAGCTGAAGAAAGTGAAAGGGCTGGGC
CCAAAATCCTTCCAACAGTGTGCTGGCTTCATCAGAATCAACCAGGATTATATCCGAACGTTTTGCAGTCAGCAAACTGAAACTTCAGGC
CAAATTCAAGGAGTTGCTGTGACATCTTCAGCAGACGTTGAGGTCACAAATGAGAAGCAGGGCAAAAAGAAGAGCAAAACTGCAGTGAAT
GTTTTACTGAAGCCAAATCCTTTGGACCAAACTTGTATTCATCCAGAATCATATGACATAGCAATGAGGTTTTTGTCATCCATTGGAGGG
ACACTGTATGAGGTTGGAAAGCCTGAAATGCAACAAAAAATAAATTCATTCCTTGAAAAGGAAGGAATGGAGAAAATTGCAGAAAGATTG
CAAACAACAGTACACACCTTACAGGTCATCATAGATGGTCTCAGCCAGCCTGAAAGCTTTGACTTTCGAACAGATTTTGATAAACCTGAT
TTCAAGAGAAGCATAGTATGCCTGGAAGATCTGCAGATTGGGACAGTTCTTACAGGCAAAGTTGAGAATGCCACTCTCTTTGGAATTTTT
GTGGATATAGGAGTGGGGAAATCTGGGCTGATTCCCATACGAAATGTAACAGAAGCAAAACTTTCAAAAACAAAGAAGAGAAGAAGCCTT
GGACTGGGCCCCGGAGAAAGAGTGGAAGTCCAAGTACTCAACATTGACATCCCCCGATCTAGGATTACTCTGGACCTCATTCGGGTGTTA
TGAGTATCCCACGAAGGCCAGACGCTGATTTTATTTTCTCATTTCCACAGATTGACAAGGATAAGTCAGTTGTTTGTAAACTCTAGGTAG
CAGATGAGAAATAATTCACTTAATATCAGAAATATTTTCCAAACACTTTCCTTTATTTTTTCTTCTGAATAAATAGAAAACCAACAGTTT
GATTTCCTTTTCCCTTAAAGGAAACAACTAATACACATTCTTATATGGCTTTATGTAGTAATAGTTTTCTGACTAAAATTTTGTTTTTTA
TTTTTTGTAATTTATCTTTAACTCCTTTTGCATTTTGTATAACAGATTGCTTAACTTCTACTTGCCAACATCTGCCTTGCTGGACTTGTA
TGGGATTGTCTTCTTGATTTGAATTGTACCGTCTTTGTTGACACAGTAGGGCTGGGCAGTGTTTAATCCTTCCATTTTATAGATTTTTTT
TTAATCAGGCCTTTTGGACTTCATTCATAATTTTGCAATAATCTCTTTTCCCTTGTCATGCAAGCCAAAAATATACCAGTAAAACAGATT
CTGACGTGTTTGTAGTTATCAAATGAATGGCTCGAAACACTTCTCAAAAGGATATACGTATTGACCCCAACAATAAATGTTTGTGGCTAG

>52193_52193_7_MCFD2-SRBD1_MCFD2_chr2_47136162_ENST00000409105_SRBD1_chr2_45715470_ENST00000263736_length(amino acids)=447AA_BP=77
MGACRTNTYTRLGIEKTSLEKETFDILMTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQDIVSEAGASIYSVS
PEANKEMPGLDPNLRSAVSIARRVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANR
AKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQTETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNVLL
KPNPLDQTCIHPESYDIAMRFLSSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTDFDKPDFKR

--------------------------------------------------------------
>52193_52193_8_MCFD2-SRBD1_MCFD2_chr2_47136162_ENST00000409105_SRBD1_chr2_45715470_ENST00000535761_length(transcript)=1660nt_BP=329nt
ACGGGGGCTGGTGAGGCTCACGTTGGAGGGCTTCGCGTCTGCTTCGGAGACCGTAAGGCTGTCATCAGCTGTGGACGGGAGCCTTCTGAA
GGGAAGCACTTGGGAGCCTGCAGGACGAATACCTACACCAGACTTGGAATTGAAAAGACCTCACTGGAGAAAGAGACATTTGATATATTG
ATGACCATGAGATCCCTGCTCAGAACCCCCTTCCTGTGTGGCCTGCTCTGGGCCTTTTGTGCCCCAGGCGCCAGGGCTGAGGAGCCTGCA
GCCAGCTTCTCCCAACCCGGCAGCATGGGCCTGGATAAGAACACAGTGCACGACCAAGATATCGTCAGTGAAGCAGGAGCATCAATCTAC
AGTGTCAGCCCTGAAGCTAACAAAGAGATGCCAGGGCTGGACCCTAATTTGAGAAGTGCAGTTTCCATAGCAAGGCGTGTACAAGATCCA
TTAGCTGAGCTAGTGAAAATTGAGCCAAAGCACATTGGAGTTGGAATGTATCAGCATGACGTATCCCAGACTTTACTCAAGGCAACACTG
GACAGTGTTGTAGAAGAATGTGTCAGCTTTGTGGGAGTGGATATTAACATCTGTTCAGAAGTTTTGTTAAGGCATATTGCAGGACTCAAT
GCCAACAGGGCCAAAAATATTATTGAATGGCGAGAGAAAAATGGACCCTTTATCAACCGAGAACAGCTGAAGAAAGTGAAAGGGCTGGGC
CCAAAATCCTTCCAACAGTGTGCTGGCTTCATCAGAATCAACCAGGATTATATCCGAACGTTTTGCAGTCAGCAAACTGAAACTTCAGGC
CAAATTCAAGGAGTTGCTGTGACATCTTCAGCAGACGTTGAGGTCACAAATGAGAAGCAGGGCAAAAAGAAGAGCAAAACTGCAGTGAAT
GTTTTACTGAAGCCAAATCCTTTGGACCAAACTTGTATTCATCCAGAATCATATGACATAGCAATGAGGTTTTTGTCATCCATTGGAGGG
ACACTGTATGAGGTTGGAAAGCCTGAAATGCAACAAAAAATAAATTCATTCCTTGAAAAGGAAGGAATGGAGAAAATTGCAGAAAGATTG
CAAACAACAGTACACACCTTACAGGTCATCATAGATGGTCTCAGCCAGCCTGAAAGCTTTGACTTTCGAACAGATTTTGATAAACCTGAT
TTCAAGAGAAGCATAGTATGCCTGGAAGATCTGCAGATTGGGACAGTTCTTACAGGCAAAGTTGAGAATGCCACTCTCTTTGGAATTTTT
GTGGATATAGGAGTGGGGAAATCTGGGCTGATTCCCATACGAAATGTAACAGAAGCAAAACTTTCAAAAACAAAGAAGAGAAGAAGCCTT
GGACTGGGCCCCGGAGAAAGAGTGGAAGTCCAAGTACTCAACATTGACATCCCCCGATCTAGGATTACTCTGGACCTCATTCGGGTGTTA
TGAGTATCCCACGAAGGCCAGACGCTGATTTTATTTTCTCATTTCCACAGATTGACAAGGATAAGTCAGTTGTTTGTAAACTCTAGGTAG
CAGATGAGAAATAATTCACTTAATATCAGAAATATTTTCCAAACACTTTCCTTTATTTTTTCTTCTGAATAAATAGAAAACCAACAGTTT

>52193_52193_8_MCFD2-SRBD1_MCFD2_chr2_47136162_ENST00000409105_SRBD1_chr2_45715470_ENST00000535761_length(amino acids)=447AA_BP=77
MGACRTNTYTRLGIEKTSLEKETFDILMTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQDIVSEAGASIYSVS
PEANKEMPGLDPNLRSAVSIARRVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNANR
AKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQTETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNVLL
KPNPLDQTCIHPESYDIAMRFLSSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTDFDKPDFKR

--------------------------------------------------------------
>52193_52193_9_MCFD2-SRBD1_MCFD2_chr2_47136162_ENST00000409207_SRBD1_chr2_45715470_ENST00000263736_length(transcript)=2060nt_BP=316nt
TACTCACCGGTGTCCGGAAAGGTGAACGCTGCGCTCGGGCTGCCTCGCCTGTTACCTCCGCCGCCGGGCATGCTCAGCGTCTGCAGCTGC
CGGACCAGCTCCGGCATGCGGTCCCAGTGGCCCTCGGCGCGGCAGCGCTCCAGCTCGCTCTCCACCTTCAGATATTGATGACCATGAGAT
CCCTGCTCAGAACCCCCTTCCTGTGTGGCCTGCTCTGGGCCTTTTGTGCCCCAGGCGCCAGGGCTGAGGAGCCTGCAGCCAGCTTCTCCC
AACCCGGCAGCATGGGCCTGGATAAGAACACAGTGCACGACCAAGATATCGTCAGTGAAGCAGGAGCATCAATCTACAGTGTCAGCCCTG
AAGCTAACAAAGAGATGCCAGGGCTGGACCCTAATTTGAGAAGTGCAGTTTCCATAGCAAGGCGTGTACAAGATCCATTAGCTGAGCTAG
TGAAAATTGAGCCAAAGCACATTGGAGTTGGAATGTATCAGCATGACGTATCCCAGACTTTACTCAAGGCAACACTGGACAGTGTTGTAG
AAGAATGTGTCAGCTTTGTGGGAGTGGATATTAACATCTGTTCAGAAGTTTTGTTAAGGCATATTGCAGGACTCAATGCCAACAGGGCCA
AAAATATTATTGAATGGCGAGAGAAAAATGGACCCTTTATCAACCGAGAACAGCTGAAGAAAGTGAAAGGGCTGGGCCCAAAATCCTTCC
AACAGTGTGCTGGCTTCATCAGAATCAACCAGGATTATATCCGAACGTTTTGCAGTCAGCAAACTGAAACTTCAGGCCAAATTCAAGGAG
TTGCTGTGACATCTTCAGCAGACGTTGAGGTCACAAATGAGAAGCAGGGCAAAAAGAAGAGCAAAACTGCAGTGAATGTTTTACTGAAGC
CAAATCCTTTGGACCAAACTTGTATTCATCCAGAATCATATGACATAGCAATGAGGTTTTTGTCATCCATTGGAGGGACACTGTATGAGG
TTGGAAAGCCTGAAATGCAACAAAAAATAAATTCATTCCTTGAAAAGGAAGGAATGGAGAAAATTGCAGAAAGATTGCAAACAACAGTAC
ACACCTTACAGGTCATCATAGATGGTCTCAGCCAGCCTGAAAGCTTTGACTTTCGAACAGATTTTGATAAACCTGATTTCAAGAGAAGCA
TAGTATGCCTGGAAGATCTGCAGATTGGGACAGTTCTTACAGGCAAAGTTGAGAATGCCACTCTCTTTGGAATTTTTGTGGATATAGGAG
TGGGGAAATCTGGGCTGATTCCCATACGAAATGTAACAGAAGCAAAACTTTCAAAAACAAAGAAGAGAAGAAGCCTTGGACTGGGCCCCG
GAGAAAGAGTGGAAGTCCAAGTACTCAACATTGACATCCCCCGATCTAGGATTACTCTGGACCTCATTCGGGTGTTATGAGTATCCCACG
AAGGCCAGACGCTGATTTTATTTTCTCATTTCCACAGATTGACAAGGATAAGTCAGTTGTTTGTAAACTCTAGGTAGCAGATGAGAAATA
ATTCACTTAATATCAGAAATATTTTCCAAACACTTTCCTTTATTTTTTCTTCTGAATAAATAGAAAACCAACAGTTTGATTTCCTTTTCC
CTTAAAGGAAACAACTAATACACATTCTTATATGGCTTTATGTAGTAATAGTTTTCTGACTAAAATTTTGTTTTTTATTTTTTGTAATTT
ATCTTTAACTCCTTTTGCATTTTGTATAACAGATTGCTTAACTTCTACTTGCCAACATCTGCCTTGCTGGACTTGTATGGGATTGTCTTC
TTGATTTGAATTGTACCGTCTTTGTTGACACAGTAGGGCTGGGCAGTGTTTAATCCTTCCATTTTATAGATTTTTTTTTAATCAGGCCTT
TTGGACTTCATTCATAATTTTGCAATAATCTCTTTTCCCTTGTCATGCAAGCCAAAAATATACCAGTAAAACAGATTCTGACGTGTTTGT

>52193_52193_9_MCFD2-SRBD1_MCFD2_chr2_47136162_ENST00000409207_SRBD1_chr2_45715470_ENST00000263736_length(amino acids)=449AA_BP=79
MQLPDQLRHAVPVALGAAALQLALHLQILMTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQDIVSEAGASIYS
VSPEANKEMPGLDPNLRSAVSIARRVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNA
NRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQTETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNV
LLKPNPLDQTCIHPESYDIAMRFLSSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTDFDKPDF

--------------------------------------------------------------
>52193_52193_10_MCFD2-SRBD1_MCFD2_chr2_47136162_ENST00000409207_SRBD1_chr2_45715470_ENST00000535761_length(transcript)=1647nt_BP=316nt
TACTCACCGGTGTCCGGAAAGGTGAACGCTGCGCTCGGGCTGCCTCGCCTGTTACCTCCGCCGCCGGGCATGCTCAGCGTCTGCAGCTGC
CGGACCAGCTCCGGCATGCGGTCCCAGTGGCCCTCGGCGCGGCAGCGCTCCAGCTCGCTCTCCACCTTCAGATATTGATGACCATGAGAT
CCCTGCTCAGAACCCCCTTCCTGTGTGGCCTGCTCTGGGCCTTTTGTGCCCCAGGCGCCAGGGCTGAGGAGCCTGCAGCCAGCTTCTCCC
AACCCGGCAGCATGGGCCTGGATAAGAACACAGTGCACGACCAAGATATCGTCAGTGAAGCAGGAGCATCAATCTACAGTGTCAGCCCTG
AAGCTAACAAAGAGATGCCAGGGCTGGACCCTAATTTGAGAAGTGCAGTTTCCATAGCAAGGCGTGTACAAGATCCATTAGCTGAGCTAG
TGAAAATTGAGCCAAAGCACATTGGAGTTGGAATGTATCAGCATGACGTATCCCAGACTTTACTCAAGGCAACACTGGACAGTGTTGTAG
AAGAATGTGTCAGCTTTGTGGGAGTGGATATTAACATCTGTTCAGAAGTTTTGTTAAGGCATATTGCAGGACTCAATGCCAACAGGGCCA
AAAATATTATTGAATGGCGAGAGAAAAATGGACCCTTTATCAACCGAGAACAGCTGAAGAAAGTGAAAGGGCTGGGCCCAAAATCCTTCC
AACAGTGTGCTGGCTTCATCAGAATCAACCAGGATTATATCCGAACGTTTTGCAGTCAGCAAACTGAAACTTCAGGCCAAATTCAAGGAG
TTGCTGTGACATCTTCAGCAGACGTTGAGGTCACAAATGAGAAGCAGGGCAAAAAGAAGAGCAAAACTGCAGTGAATGTTTTACTGAAGC
CAAATCCTTTGGACCAAACTTGTATTCATCCAGAATCATATGACATAGCAATGAGGTTTTTGTCATCCATTGGAGGGACACTGTATGAGG
TTGGAAAGCCTGAAATGCAACAAAAAATAAATTCATTCCTTGAAAAGGAAGGAATGGAGAAAATTGCAGAAAGATTGCAAACAACAGTAC
ACACCTTACAGGTCATCATAGATGGTCTCAGCCAGCCTGAAAGCTTTGACTTTCGAACAGATTTTGATAAACCTGATTTCAAGAGAAGCA
TAGTATGCCTGGAAGATCTGCAGATTGGGACAGTTCTTACAGGCAAAGTTGAGAATGCCACTCTCTTTGGAATTTTTGTGGATATAGGAG
TGGGGAAATCTGGGCTGATTCCCATACGAAATGTAACAGAAGCAAAACTTTCAAAAACAAAGAAGAGAAGAAGCCTTGGACTGGGCCCCG
GAGAAAGAGTGGAAGTCCAAGTACTCAACATTGACATCCCCCGATCTAGGATTACTCTGGACCTCATTCGGGTGTTATGAGTATCCCACG
AAGGCCAGACGCTGATTTTATTTTCTCATTTCCACAGATTGACAAGGATAAGTCAGTTGTTTGTAAACTCTAGGTAGCAGATGAGAAATA
ATTCACTTAATATCAGAAATATTTTCCAAACACTTTCCTTTATTTTTTCTTCTGAATAAATAGAAAACCAACAGTTTGATTTCCTTTTCC

>52193_52193_10_MCFD2-SRBD1_MCFD2_chr2_47136162_ENST00000409207_SRBD1_chr2_45715470_ENST00000535761_length(amino acids)=449AA_BP=79
MQLPDQLRHAVPVALGAAALQLALHLQILMTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQDIVSEAGASIYS
VSPEANKEMPGLDPNLRSAVSIARRVQDPLAELVKIEPKHIGVGMYQHDVSQTLLKATLDSVVEECVSFVGVDINICSEVLLRHIAGLNA
NRAKNIIEWREKNGPFINREQLKKVKGLGPKSFQQCAGFIRINQDYIRTFCSQQTETSGQIQGVAVTSSADVEVTNEKQGKKKSKTAVNV
LLKPNPLDQTCIHPESYDIAMRFLSSIGGTLYEVGKPEMQQKINSFLEKEGMEKIAERLQTTVHTLQVIIDGLSQPESFDFRTDFDKPDF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MCFD2-SRBD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MCFD2-SRBD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MCFD2-SRBD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource