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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ABLIM3-AZU1 (FusionGDB2 ID:523)

Fusion Gene Summary for ABLIM3-AZU1

Fusion gene summary

Fusion gene information	Fusion gene name: ABLIM3-AZU1
	Fusion gene ID: 523
		Hgene	Tgene
	Gene symbol	ABLIM3	AZU1
	Gene ID	22885	566
	Gene name	actin binding LIM protein family member 3	azurocidin 1
	Synonyms	HMFN1661	AZAMP\|AZU\|CAP37\|HBP\|HUMAZUR\|NAZC\|hHBP
	Cytomap	5q32	19p13.3
	Type of gene	protein-coding	protein-coding
	Description	actin-binding LIM protein 3abLIM-3	azurocidincationic antimicrobial protein 37cationic antimicrobial protein CAP37heparin-binding proteinneutrophil azurocidin
	Modification date	20200313	20200313
	UniProtAcc	O94929	P20160
	Ensembl transtripts involved in fusion gene	ENST00000309868, ENST00000326685, ENST00000356541, ENST00000504238, ENST00000506113, ENST00000508983, ENST00000517451, ENST00000519549,	ENST00000233997,
Fusion gene scores	* DoF score	4 X 4 X 3=48	3 X 2 X 3=18
	# samples	4	4
	** MAII score	log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(4/18*10)=1.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: ABLIM3 [Title/Abstract] AND AZU1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ABLIM3(148627492)-AZU1(828230), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	AZU1	GO:0006508	proteolysis	21550830
Tgene	AZU1	GO:0008347	glial cell migration	12465046
Tgene	AZU1	GO:0010800	positive regulation of peptidyl-threonine phosphorylation	24008408
Tgene	AZU1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	12465046
Tgene	AZU1	GO:0045785	positive regulation of cell adhesion	12826073\|15879141
Tgene	AZU1	GO:0045860	positive regulation of protein kinase activity	24008408
Tgene	AZU1	GO:0050725	positive regulation of interleukin-1 beta biosynthetic process	12465046
Tgene	AZU1	GO:0050754	positive regulation of fractalkine biosynthetic process	12465046
Tgene	AZU1	GO:0050766	positive regulation of phagocytosis	12465046
Tgene	AZU1	GO:0070944	neutrophil mediated killing of bacterium	2312733

Fusion gene breakpoints across ABLIM3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across AZU1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-C8-A12X-01A	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+

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Fusion Gene ORF analysis for ABLIM3-AZU1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
In-frame	ENST00000309868	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+
In-frame	ENST00000326685	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+
In-frame	ENST00000356541	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+
In-frame	ENST00000504238	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+
In-frame	ENST00000506113	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+
In-frame	ENST00000508983	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+
In-frame	ENST00000517451	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+
intron-3CDS	ENST00000519549	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000326685	ABLIM3	chr5	148627492	+	ENST00000233997	AZU1	chr19	828230	+	2511	1673	259	2370	703
ENST00000356541	ABLIM3	chr5	148627492	+	ENST00000233997	AZU1	chr19	828230	+	2455	1617	251	2314	687
ENST00000309868	ABLIM3	chr5	148627492	+	ENST00000233997	AZU1	chr19	828230	+	2776	1938	239	2635	798
ENST00000506113	ABLIM3	chr5	148627492	+	ENST00000233997	AZU1	chr19	828230	+	3019	2181	482	2878	798
ENST00000504238	ABLIM3	chr5	148627492	+	ENST00000233997	AZU1	chr19	828230	+	2479	1641	275	2338	687
ENST00000508983	ABLIM3	chr5	148627492	+	ENST00000233997	AZU1	chr19	828230	+	2487	1649	49	2346	765
ENST00000517451	ABLIM3	chr5	148627492	+	ENST00000233997	AZU1	chr19	828230	+	2719	1881	2359	1292	355

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000326685	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+	0.02446399	0.97553605
ENST00000356541	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+	0.029264534	0.9707355
ENST00000309868	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+	0.013013917	0.9869861
ENST00000506113	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+	0.00969195	0.990308
ENST00000504238	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+	0.024338929	0.97566104
ENST00000508983	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+	0.013139925	0.9868601
ENST00000517451	ENST00000233997	ABLIM3	chr5	148627492	+	AZU1	chr19	828230	+	0.35011834	0.64988166

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Fusion Genomic Features for ABLIM3-AZU1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
ABLIM3	chr5	148627492	+	AZU1	chr19	828229	+	0.021719752	0.9782802
ABLIM3	chr5	148627492	+	AZU1	chr19	828229	+	0.021719752	0.9782802

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ABLIM3-AZU1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:148627492/chr19:828230)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ABLIM3 O94929	AZU1 P20160
FUNCTION: May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity. {ECO:0000269\|PubMed:17194709}.	FUNCTION: This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. It may play a role in mediating recruitment of monocytes in the second wave of inflammation. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. Acting alone, it does not have antimicrobial activity against the Gram-negative bacteria A.actinomycetemcomitans ATCC 29532, A.actinomycetemcomitans NCTC 9709, A.actinomycetemcomitans FDC-Y4, H.aphrophilus ATCC 13252, E.corrodens ATCC 23834, C.sputigena ATCC 33123, Capnocytophaga sp ATCC 33124, Capnocytophaga sp ATCC 27872 or E.coli ML-35. Has antibacterial activity against C.sputigena ATCC 33123 when acting synergistically with either elastase or cathepsin G. {ECO:0000269\|PubMed:1399008, ECO:0000269\|PubMed:1937776, ECO:0000269\|PubMed:2312733}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000309868

149_208

566

684.0

Domain

LIM zinc-binding 3

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000309868

208_268

566

684.0

Domain

LIM zinc-binding 4

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000309868

21_80

566

684.0

Domain

LIM zinc-binding 1

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000309868

80_140

566

684.0

Domain

LIM zinc-binding 2

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000326685

149_208

471

589.0

Domain

LIM zinc-binding 3

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000326685

208_268

471

589.0

Domain

LIM zinc-binding 4

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000326685

21_80

471

589.0

Domain

LIM zinc-binding 1

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000326685

80_140

471

589.0

Domain

LIM zinc-binding 2

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000356541

149_208

455

545.0

Domain

LIM zinc-binding 3

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000356541

208_268

455

545.0

Domain

LIM zinc-binding 4

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000356541

21_80

455

545.0

Domain

LIM zinc-binding 1

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000356541

80_140

455

545.0

Domain

LIM zinc-binding 2

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000504238

149_208

455

545.0

Domain

LIM zinc-binding 3

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000504238

208_268

455

545.0

Domain

LIM zinc-binding 4

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000504238

21_80

455

545.0

Domain

LIM zinc-binding 1

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000504238

80_140

455

545.0

Domain

LIM zinc-binding 2

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000506113

149_208

566

684.0

Domain

LIM zinc-binding 3

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000506113

208_268

566

684.0

Domain

LIM zinc-binding 4

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000506113

21_80

566

684.0

Domain

LIM zinc-binding 1

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000506113

80_140

566

684.0

Domain

LIM zinc-binding 2

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000508983

149_208

533

651.0

Domain

LIM zinc-binding 3

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000508983

208_268

533

651.0

Domain

LIM zinc-binding 4

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000508983

21_80

533

651.0

Domain

LIM zinc-binding 1

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000508983

80_140

533

651.0

Domain

LIM zinc-binding 2

Tgene

AZU1

chr5:148627492

chr19:828230

ENST00000233997

27_244

252.0

Domain

Peptidase S1

Tgene

AZU1

chr5:148627492

chr19:828230

ENST00000233997

46_70

252.0

Region

Possesses antibiotic activity

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000309868

615_683

566

684.0

Domain

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000326685

615_683

471

589.0

Domain

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000356541

615_683

455

545.0

Domain

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000504238

615_683

455

545.0

Domain

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000506113

615_683

566

684.0

Domain

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000508983

615_683

533

651.0

Domain

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000517451

149_208

170.0

Domain

LIM zinc-binding 3

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000517451

208_268

170.0

Domain

LIM zinc-binding 4

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000517451

21_80

170.0

Domain

LIM zinc-binding 1

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000517451

615_683

170.0

Domain

Hgene

ABLIM3

chr5:148627492

chr19:828230

ENST00000517451

80_140

170.0

Domain

LIM zinc-binding 2

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Fusion Gene Sequence for ABLIM3-AZU1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>523_523_1_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000309868_AZU1_chr19_828230_ENST00000233997_length(transcript)=2776nt_BP=1938nt
CTGCCAACCCGCGAGCCCGCATCATGGATGTCGAGCTCCCCTATTTCGCATTGCTAGCCCTGGAATTCGAGACCCCAGACGAGGACCAGG
ATTCATGAAATCAGTCGCAGGGGCCGGGGCAGGGGCCTCTGGCTCCCGACACTGGCCGAGAGGTGATGAGTGAGGTTCGAAGAACGGAAG
ATTTAAAAAGCAGCCGGGGCCTCCGTATTGAATGAAAGACCCAGTGCAAAGACATCACCATGAACACTAGCATTCCTTATCAGCAGAATC
CTTACAATCCACGGGGCAGCTCCAATGTCATCCAGTGCTACCGCTGTGGAGACACCTGCAAAGGGGAAGTGGTCCGCGTGCACAACAACC
ACTTCCACATCAGATGCTTCACCTGTCAAGTATGTGGCTGTGGCCTGGCCCAGTCAGGCTTCTTCTTCAAGAACCAGGAGTACATCTGCA
CCCAGGACTACCAGCAACTCTATGGCACCCGCTGTGACAGCTGCCGGGACTTCATCACAGGCGAAGTCATCTCGGCCCTGGGCCGCACTT
ACCACCCCAAGTGCTTCGTGTGCAGCTTGTGCAGGAAGCCTTTCCCCATTGGAGACAAGGTGACCTTCAGCGGTAAAGAATGTGTGTGCC
AAACGTGCTCCCAGTCCATGGCCAGCAGTAAGCCCATCAAGATTCGTGGACCAAGCCACTGTGCCGGGTGCAAGGAGGAGATCAAGCACG
GCCAGTCACTCCTGGCTCTGGACAAGCAGTGGCACGTCAGCTGCTTCAAGTGCCAGACCTGCAGCGTCATCCTCACCGGGGAGTATATCA
GCAAGGATGGTGTTCCATACTGTGAGTCCGACTACCATGCCCAGTTTGGCATTAAATGTGAGACTTGTGACCGATACATCAGTGGCAGAG
TCTTGGAGGCAGGAGGGAAGCACTACCACCCAACCTGTGCCAGGTGTGTACGCTGCCACCAGATGTTCACCGAAGGAGAGGAAATGTACC
TCACAGGTTCCGAGGTTTGGCACCCCATCTGCAAACAGGCAGCCCGGGCAGAGAAGAAGTTAAAGCATAGACGGACATCTGAAACCTCCA
TCTCACCCCCTGGATCCAGCATTGGGTCACCCAACCGAGTCATCTGCGCTAAAGTGGATAATGAGATCCTTAATTACAAAGACCTGGCGG
CTCTCCCCAAGGTTAAGTCTATCTACGAGGTACAACGCCCCGACCTCATTTCCTATGAGCCTCATTCCAGATACATGTCCGACGAGATGC
TGGAGAGATGTGGCTATGGAGAGTCGCTGGGAACATTATCTCCCTACTCCCAGGACATCTACGAGAACCTGGACCTCCGGCAGAGACGGG
CCTCCAGCCCGGGGTACATAGACTCCCCCACCTACAGCCGGCAGGGCATGTCCCCCACCTTCTCCCGCTCACCTCACCACTACTACCGCT
CTGGGCCCGAGAGTGGCCGGAGCTCTCCATACCATAGCCAGTTAGATGTGAGGTCCTCCACTCCAACCTCTTACCAGGCTCCCAAGCACT
TTCACATCCCAGCTGGAGACAGTAACATCTACCGGAAACCCCCGATCTACAAACGGCATGGTGATTTGTCTACAGCAACCAAGAGCAAAA
CAAGTGAAGACATCAGCCAGACCTCCAAGTACAGTCCCATCTACTCGCCAGACCCCTACTATGCTTCGGAGTCTGAGTACTGGACCTACC
ATGGGTCCCCCAAAGTGCCCCGAGCCAGAAGGTTCTCGTCTGGAGGAGAGGAGGATGATTTTGACCGCAGCATGCACAAGCTCCAAAGTG
GAATTGGCCGGCTGATTCTGAAGGAAGAAATGAAGGCCCGGTCGAGCTCCTATGCAGATCCCTGGACCCCTCCCCGGAGCTCCACCAGCA
GCCGGGAAGCCCTGCACACAGCTGGCTATGAGATGTCCCTCAATGGCTGCTCCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAAGGCGA
GGCCCCGCCAGTTCCCGTTCCTGGCCTCCATTCAGAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGTGATGA
CCGCGGCCAGCTGCTTCCAAAGCCAGAACCCCGGGGTTAGCACCGTGGTGCTGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCAGTCCC
GCCAGACGTTTTCCATCAGCAGCATGAGCGAGAATGGCTACGACCCCCAGCAGAACCTGAACGACCTGATGCTGCTTCAGCTGGACCGTG
AGGCCAACCTCACCAGCAGCGTGACGATACTGCCACTGCCTCTGCAGAACGCCACGGTGGAAGCCGGCACCAGATGCCAGGTGGCCGGCT
GGGGGAGCCAGCGCAGTGGGGGGCGTCTCTCCCGTTTTCCCAGGTTTGTCAACGTGACTGTGACCCCCGAGGACCAGTGTCGCCCCAACA
ACGTGTGCACCGGTGTGCTCACCCGCCGCGGTGGCATCTGCAATGGGGACGGGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCG
TGGCCTCCTTTTCCCTGGGGCCCTGTGGCCGAGGCCCTGACTTCTTCACCCGAGTGGCGCTCTTCCGAGACTGGATCGATGGTGTTCTCA
ACAACCCGGGACCGGGGCCAGCCTAGGGGGGCCTGTGACCTCCCATGGAGCCCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCACCCAC

>523_523_1_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000309868_AZU1_chr19_828230_ENST00000233997_length(amino acids)=798AA_BP=567
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICAKVDNEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI
YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSSTPTSYQAPKHFHIPAGDSNIYRKPPIYKRH
GDLSTATKSKTSEDISQTSKYSPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD
PWTPPRSSTSSREALHTAGYEMSLNGCSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA
YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVT

--------------------------------------------------------------
>523_523_2_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000326685_AZU1_chr19_828230_ENST00000233997_length(transcript)=2511nt_BP=1673nt
GAGCGGCCGCGCCCCCTGCGCTGCCAACCCGCGAGCCCGCATCATGGATGTCGAGCTCCCCTATTTCGCATTGCTAGCCCTGGAATTCGA
GACCCCAGACGAGGACCAGGATTCATGAAATCAGTCGCAGGGGCCGGGGCAGGGGCCTCTGGCTCCCGACACTGGCCGAGAGGTGATGAG
TGAGGTTCGAAGAACGGAAGATTTAAAAAGCAGCCGGGGCCTCCGTATTGAATGAAAGACCCAGTGCAAAGACATCACCATGAACACTAG
CATTCCTTATCAGCAGAATCCTTACAATCCACGGGGCAGCTCCAATGTCATCCAGTGCTACCGCTGTGGAGACACCTGCAAAGGGGAAGT
GGTCCGCGTGCACAACAACCACTTCCACATCAGATGCTTCACCTGTCAAGTATGTGGCTGTGGCCTGGCCCAGTCAGGCTTCTTCTTCAA
GAACCAGGAGTACATCTGCACCCAGGACTACCAGCAACTCTATGGCACCCGCTGTGACAGCTGCCGGGACTTCATCACAGGCGAAGTCAT
CTCGGCCCTGGGCCGCACTTACCACCCCAAGTGCTTCGTGTGCAGCTTGTGCAGGAAGCCTTTCCCCATTGGAGACAAGGTGACCTTCAG
CGGTAAAGAATGTGTGTGCCAAACGTGCTCCCAGTCCATGGCCAGCAGTAAGCCCATCAAGATTCGTGGACCAAGCCACTGTGCCGGGTG
CAAGGAGGAGATCAAGCACGGCCAGTCACTCCTGGCTCTGGACAAGCAGTGGCACGTCAGCTGCTTCAAGTGCCAGACCTGCAGCGTCAT
CCTCACCGGGGAGTATATCAGCAAGGATGGTGTTCCATACTGTGAGTCCGACTACCATGCCCAGTTTGGCATTAAATGTGAGACTTGTGA
CCGATACATCAGTGGCAGAGTCTTGGAGGCAGGAGGGAAGCACTACCACCCAACCTGTGCCAGGTGTGTACGCTGCCACCAGATGTTCAC
CGAAGGAGAGGAAATGTACCTCACAGGTTCCGAGGTTTGGCACCCCATCTGCAAACAGGCAGCCCGGGCAGAGAAGAAGTTAAAGCATAG
ACGGACATCTGAAACCTCCATCTCACCCCCTGGATCCAGCATTGGGTCACCCAACCGAGTCATCTGCGACATCTACGAGAACCTGGACCT
CCGGCAGAGACGGGCCTCCAGCCCGGGGTACATAGACTCCCCCACCTACAGCCGGCAGGGCATGTCCCCCACCTTCTCCCGCTCACCTCA
CCACTACTACCGCTCTGCTGGAGACAGTAACATCTACCGGAAACCCCCGATCTACAAACGGCATGGTGATTTGTCTACAGCAACCAAGAG
CAAAACAAGTGAAGACATCAGCCAGACCTCCAAGTACAGTCCCATCTACTCGCCAGACCCCTACTATGCTTCGGAGTCTGAGTACTGGAC
CTACCATGGGTCCCCCAAAGTGCCCCGAGCCAGAAGGTTCTCGTCTGGAGGAGAGGAGGATGATTTTGACCGCAGCATGCACAAGCTCCA
AAGTGGAATTGGCCGGCTGATTCTGAAGGAAGAAATGAAGGCCCGGTCGAGCTCCTATGCAGATCCCTGGACCCCTCCCCGGAGCTCCAC
CAGCAGCCGGGAAGCCCTGCACACAGCTGGCTATGAGATGTCCCTCAATGGCTGCTCCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAA
GGCGAGGCCCCGCCAGTTCCCGTTCCTGGCCTCCATTCAGAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGT
GATGACCGCGGCCAGCTGCTTCCAAAGCCAGAACCCCGGGGTTAGCACCGTGGTGCTGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCA
GTCCCGCCAGACGTTTTCCATCAGCAGCATGAGCGAGAATGGCTACGACCCCCAGCAGAACCTGAACGACCTGATGCTGCTTCAGCTGGA
CCGTGAGGCCAACCTCACCAGCAGCGTGACGATACTGCCACTGCCTCTGCAGAACGCCACGGTGGAAGCCGGCACCAGATGCCAGGTGGC
CGGCTGGGGGAGCCAGCGCAGTGGGGGGCGTCTCTCCCGTTTTCCCAGGTTTGTCAACGTGACTGTGACCCCCGAGGACCAGTGTCGCCC
CAACAACGTGTGCACCGGTGTGCTCACCCGCCGCGGTGGCATCTGCAATGGGGACGGGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCA
CGGCGTGGCCTCCTTTTCCCTGGGGCCCTGTGGCCGAGGCCCTGACTTCTTCACCCGAGTGGCGCTCTTCCGAGACTGGATCGATGGTGT
TCTCAACAACCCGGGACCGGGGCCAGCCTAGGGGGGCCTGTGACCTCCCATGGAGCCCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCA

>523_523_2_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000326685_AZU1_chr19_828230_ENST00000233997_length(amino acids)=703AA_BP=472
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICDIYENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSAGDSNIYRKPPIYKRHGDLST
ATKSKTSEDISQTSKYSPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYADPWTPP
RSSTSSREALHTAGYEMSLNGCSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRR
RERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPED

--------------------------------------------------------------
>523_523_3_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000356541_AZU1_chr19_828230_ENST00000233997_length(transcript)=2455nt_BP=1617nt
GCGCCCCCTGCGCTGCCAACCCGCGAGCCCGCATCATGGATGTCGAGCTCCCCTATTTCGCATTGCTAGCCCTGGAATTCGAGACCCCAG
ACGAGGACCAGGATTCATGAAATCAGTCGCAGGGGCCGGGGCAGGGGCCTCTGGCTCCCGACACTGGCCGAGAGGTGATGAGTGAGGTTC
GAAGAACGGAAGATTTAAAAAGCAGCCGGGGCCTCCGTATTGAATGAAAGACCCAGTGCAAAGACATCACCATGAACACTAGCATTCCTT
ATCAGCAGAATCCTTACAATCCACGGGGCAGCTCCAATGTCATCCAGTGCTACCGCTGTGGAGACACCTGCAAAGGGGAAGTGGTCCGCG
TGCACAACAACCACTTCCACATCAGATGCTTCACCTGTCAAGTATGTGGCTGTGGCCTGGCCCAGTCAGGCTTCTTCTTCAAGAACCAGG
AGTACATCTGCACCCAGGACTACCAGCAACTCTATGGCACCCGCTGTGACAGCTGCCGGGACTTCATCACAGGCGAAGTCATCTCGGCCC
TGGGCCGCACTTACCACCCCAAGTGCTTCGTGTGCAGCTTGTGCAGGAAGCCTTTCCCCATTGGAGACAAGGTGACCTTCAGCGGTAAAG
AATGTGTGTGCCAAACGTGCTCCCAGTCCATGGCCAGCAGTAAGCCCATCAAGATTCGTGGACCAAGCCACTGTGCCGGGTGCAAGGAGG
AGATCAAGCACGGCCAGTCACTCCTGGCTCTGGACAAGCAGTGGCACGTCAGCTGCTTCAAGTGCCAGACCTGCAGCGTCATCCTCACCG
GGGAGTATATCAGCAAGGATGGTGTTCCATACTGTGAGTCCGACTACCATGCCCAGTTTGGCATTAAATGTGAGACTTGTGACCGATACA
TCAGTGGCAGAGTCTTGGAGGCAGGAGGGAAGCACTACCACCCAACCTGTGCCAGGTGTGTACGCTGCCACCAGATGTTCACCGAAGGAG
AGGAAATGTACCTCACAGGTTCCGAGGTTTGGCACCCCATCTGCAAACAGGCAGCCCGGGCAGAGAAGAAGTTAAAGCATAGACGGACAT
CTGAAACCTCCATCTCACCCCCTGGATCCAGCATTGGGTCACCCAACCGAGTCATCTGCGACATCTACGAGAACCTGGACCTCCGGCAGA
GACGGGCCTCCAGCCCGGGGTACATAGACTCCCCCACCTACAGCCGGCAGGGCATGTCCCCCACCTTCTCCCGCTCACCTCACCACTACT
ACCGCTCTGGTGATTTGTCTACAGCAACCAAGAGCAAAACAAGTGAAGACATCAGCCAGACCTCCAAGTACAGTCCCATCTACTCGCCAG
ACCCCTACTATGCTTCGGAGTCTGAGTACTGGACCTACCATGGGTCCCCCAAAGTGCCCCGAGCCAGAAGGTTCTCGTCTGGAGGAGAGG
AGGATGATTTTGACCGCAGCATGCACAAGCTCCAAAGTGGAATTGGCCGGCTGATTCTGAAGGAAGAAATGAAGGCCCGGTCGAGCTCCT
ATGCAGATCCCTGGACCCCTCCCCGGAGCTCCACCAGCAGCCGGGAAGCCCTGCACACAGCTGGCTATGAGATGTCCCTCAATGGCTGCT
CCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTTCCTGGCCTCCATTCAGAATCAAGGCAGGCACT
TCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGTGATGACCGCGGCCAGCTGCTTCCAAAGCCAGAACCCCGGGGTTAGCACCGTGGTGC
TGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCAGTCCCGCCAGACGTTTTCCATCAGCAGCATGAGCGAGAATGGCTACGACCCCCAGC
AGAACCTGAACGACCTGATGCTGCTTCAGCTGGACCGTGAGGCCAACCTCACCAGCAGCGTGACGATACTGCCACTGCCTCTGCAGAACG
CCACGGTGGAAGCCGGCACCAGATGCCAGGTGGCCGGCTGGGGGAGCCAGCGCAGTGGGGGGCGTCTCTCCCGTTTTCCCAGGTTTGTCA
ACGTGACTGTGACCCCCGAGGACCAGTGTCGCCCCAACAACGTGTGCACCGGTGTGCTCACCCGCCGCGGTGGCATCTGCAATGGGGACG
GGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCGTGGCCTCCTTTTCCCTGGGGCCCTGTGGCCGAGGCCCTGACTTCTTCACCC
GAGTGGCGCTCTTCCGAGACTGGATCGATGGTGTTCTCAACAACCCGGGACCGGGGCCAGCCTAGGGGGGCCTGTGACCTCCCATGGAGC
CCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCACCCACCTCCCACGGCCCCGCCCCTGCCCCCGCTCCGGCCAGAGGGGCCCTGGCTGT

>523_523_3_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000356541_AZU1_chr19_828230_ENST00000233997_length(amino acids)=687AA_BP=456
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICDIYENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGDLSTATKSKTSEDISQTSKY
SPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYADPWTPPRSSTSSREALHTAGYE
MSLNGCSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE
NGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRG

--------------------------------------------------------------
>523_523_4_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000504238_AZU1_chr19_828230_ENST00000233997_length(transcript)=2479nt_BP=1641nt
CAATCTGAGGAGCAGGAGGACCGGGGCGCCGGTGTCCTGCCGCCTCCTTCTCCTTGCTCTCACCTGCGCCTATTAGTCCACGCGCCTTCA
AGGCCAGGGGCTACAGCCCAGACAGAGAGGGGACAGCAGAGGGAGAGAGAGCACCTGAGGATACAGAGCTGGCACTGGACTGCCTTTTCA
CCCCCCAGGTGATGAGTGAGGTTCGAAGAACGGAAGATTTAAAAAGCAGCCGGGGCCTCCGTATTGAATGAAAGACCCAGTGCAAAGACA
TCACCATGAACACTAGCATTCCTTATCAGCAGAATCCTTACAATCCACGGGGCAGCTCCAATGTCATCCAGTGCTACCGCTGTGGAGACA
CCTGCAAAGGGGAAGTGGTCCGCGTGCACAACAACCACTTCCACATCAGATGCTTCACCTGTCAAGTATGTGGCTGTGGCCTGGCCCAGT
CAGGCTTCTTCTTCAAGAACCAGGAGTACATCTGCACCCAGGACTACCAGCAACTCTATGGCACCCGCTGTGACAGCTGCCGGGACTTCA
TCACAGGCGAAGTCATCTCGGCCCTGGGCCGCACTTACCACCCCAAGTGCTTCGTGTGCAGCTTGTGCAGGAAGCCTTTCCCCATTGGAG
ACAAGGTGACCTTCAGCGGTAAAGAATGTGTGTGCCAAACGTGCTCCCAGTCCATGGCCAGCAGTAAGCCCATCAAGATTCGTGGACCAA
GCCACTGTGCCGGGTGCAAGGAGGAGATCAAGCACGGCCAGTCACTCCTGGCTCTGGACAAGCAGTGGCACGTCAGCTGCTTCAAGTGCC
AGACCTGCAGCGTCATCCTCACCGGGGAGTATATCAGCAAGGATGGTGTTCCATACTGTGAGTCCGACTACCATGCCCAGTTTGGCATTA
AATGTGAGACTTGTGACCGATACATCAGTGGCAGAGTCTTGGAGGCAGGAGGGAAGCACTACCACCCAACCTGTGCCAGGTGTGTACGCT
GCCACCAGATGTTCACCGAAGGAGAGGAAATGTACCTCACAGGTTCCGAGGTTTGGCACCCCATCTGCAAACAGGCAGCCCGGGCAGAGA
AGAAGTTAAAGCATAGACGGACATCTGAAACCTCCATCTCACCCCCTGGATCCAGCATTGGGTCACCCAACCGAGTCATCTGCGACATCT
ACGAGAACCTGGACCTCCGGCAGAGACGGGCCTCCAGCCCGGGGTACATAGACTCCCCCACCTACAGCCGGCAGGGCATGTCCCCCACCT
TCTCCCGCTCACCTCACCACTACTACCGCTCTGGTGATTTGTCTACAGCAACCAAGAGCAAAACAAGTGAAGACATCAGCCAGACCTCCA
AGTACAGTCCCATCTACTCGCCAGACCCCTACTATGCTTCGGAGTCTGAGTACTGGACCTACCATGGGTCCCCCAAAGTGCCCCGAGCCA
GAAGGTTCTCGTCTGGAGGAGAGGAGGATGATTTTGACCGCAGCATGCACAAGCTCCAAAGTGGAATTGGCCGGCTGATTCTGAAGGAAG
AAATGAAGGCCCGGTCGAGCTCCTATGCAGATCCCTGGACCCCTCCCCGGAGCTCCACCAGCAGCCGGGAAGCCCTGCACACAGCTGGCT
ATGAGATGTCCCTCAATGGCTGCTCCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTTCCTGGCCT
CCATTCAGAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGTGATGACCGCGGCCAGCTGCTTCCAAAGCCAGA
ACCCCGGGGTTAGCACCGTGGTGCTGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCAGTCCCGCCAGACGTTTTCCATCAGCAGCATGA
GCGAGAATGGCTACGACCCCCAGCAGAACCTGAACGACCTGATGCTGCTTCAGCTGGACCGTGAGGCCAACCTCACCAGCAGCGTGACGA
TACTGCCACTGCCTCTGCAGAACGCCACGGTGGAAGCCGGCACCAGATGCCAGGTGGCCGGCTGGGGGAGCCAGCGCAGTGGGGGGCGTC
TCTCCCGTTTTCCCAGGTTTGTCAACGTGACTGTGACCCCCGAGGACCAGTGTCGCCCCAACAACGTGTGCACCGGTGTGCTCACCCGCC
GCGGTGGCATCTGCAATGGGGACGGGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCGTGGCCTCCTTTTCCCTGGGGCCCTGTG
GCCGAGGCCCTGACTTCTTCACCCGAGTGGCGCTCTTCCGAGACTGGATCGATGGTGTTCTCAACAACCCGGGACCGGGGCCAGCCTAGG
GGGGCCTGTGACCTCCCATGGAGCCCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCACCCACCTCCCACGGCCCCGCCCCTGCCCCCGC

>523_523_4_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000504238_AZU1_chr19_828230_ENST00000233997_length(amino acids)=687AA_BP=456
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICDIYENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGDLSTATKSKTSEDISQTSKY
SPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYADPWTPPRSSTSSREALHTAGYE
MSLNGCSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSE
NGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRG

--------------------------------------------------------------
>523_523_5_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000506113_AZU1_chr19_828230_ENST00000233997_length(transcript)=3019nt_BP=2181nt
GGCCGGGGCAGGGGCCTCTGGCTCCCGACACTGGCCGAGAGGTGGGTTCCGGGGCGGGTCGCTGCTCCTTGAAGCCGGGCGGGGACGCGC
TGCCCCCGCCCTGCCTCCCTGTGGTCCACACCCCCTTTGGGCTCCGGAGCCGCTGGGCAGGAATAGTCCGGGGTGCGCGCGAGCAGGCGC
TGCCAACCCCACTTCTGCCCGGGATTCCAATCTGAGGAGCAGGAGGACCGGGGCGCCGGTGTCCTGCCGCCTCCTTCTCCTTGCTCTCAC
CTGCGCCTATTAGTCCACGCGCCTTCAAGGCCAGGGGCTACAGCCCAGACAGAGAGGGGACAGCAGAGGGAGAGAGAGCACCTGAGGATA
CAGAGCTGGCACTGGACTGCCTTTTCACCCCCCAGGTGATGAGTGAGGTTCGAAGAACGGAAGATTTAAAAAGCAGCCGGGGCCTCCGTA
TTGAATGAAAGACCCAGTGCAAAGACATCACCATGAACACTAGCATTCCTTATCAGCAGAATCCTTACAATCCACGGGGCAGCTCCAATG
TCATCCAGTGCTACCGCTGTGGAGACACCTGCAAAGGGGAAGTGGTCCGCGTGCACAACAACCACTTCCACATCAGATGCTTCACCTGTC
AAGTATGTGGCTGTGGCCTGGCCCAGTCAGGCTTCTTCTTCAAGAACCAGGAGTACATCTGCACCCAGGACTACCAGCAACTCTATGGCA
CCCGCTGTGACAGCTGCCGGGACTTCATCACAGGCGAAGTCATCTCGGCCCTGGGCCGCACTTACCACCCCAAGTGCTTCGTGTGCAGCT
TGTGCAGGAAGCCTTTCCCCATTGGAGACAAGGTGACCTTCAGCGGTAAAGAATGTGTGTGCCAAACGTGCTCCCAGTCCATGGCCAGCA
GTAAGCCCATCAAGATTCGTGGACCAAGCCACTGTGCCGGGTGCAAGGAGGAGATCAAGCACGGCCAGTCACTCCTGGCTCTGGACAAGC
AGTGGCACGTCAGCTGCTTCAAGTGCCAGACCTGCAGCGTCATCCTCACCGGGGAGTATATCAGCAAGGATGGTGTTCCATACTGTGAGT
CCGACTACCATGCCCAGTTTGGCATTAAATGTGAGACTTGTGACCGATACATCAGTGGCAGAGTCTTGGAGGCAGGAGGGAAGCACTACC
ACCCAACCTGTGCCAGGTGTGTACGCTGCCACCAGATGTTCACCGAAGGAGAGGAAATGTACCTCACAGGTTCCGAGGTTTGGCACCCCA
TCTGCAAACAGGCAGCCCGGGCAGAGAAGAAGTTAAAGCATAGACGGACATCTGAAACCTCCATCTCACCCCCTGGATCCAGCATTGGGT
CACCCAACCGAGTCATCTGCGCTAAAGTGGATAATGAGATCCTTAATTACAAAGACCTGGCGGCTCTCCCCAAGGTTAAGTCTATCTACG
AGGTACAACGCCCCGACCTCATTTCCTATGAGCCTCATTCCAGATACATGTCCGACGAGATGCTGGAGAGATGTGGCTATGGAGAGTCGC
TGGGAACATTATCTCCCTACTCCCAGGACATCTACGAGAACCTGGACCTCCGGCAGAGACGGGCCTCCAGCCCGGGGTACATAGACTCCC
CCACCTACAGCCGGCAGGGCATGTCCCCCACCTTCTCCCGCTCACCTCACCACTACTACCGCTCTGGGCCCGAGAGTGGCCGGAGCTCTC
CATACCATAGCCAGTTAGATGTGAGGTCCTCCACTCCAACCTCTTACCAGGCTCCCAAGCACTTTCACATCCCAGCTGGAGACAGTAACA
TCTACCGGAAACCCCCGATCTACAAACGGCATGGTGATTTGTCTACAGCAACCAAGAGCAAAACAAGTGAAGACATCAGCCAGACCTCCA
AGTACAGTCCCATCTACTCGCCAGACCCCTACTATGCTTCGGAGTCTGAGTACTGGACCTACCATGGGTCCCCCAAAGTGCCCCGAGCCA
GAAGGTTCTCGTCTGGAGGAGAGGAGGATGATTTTGACCGCAGCATGCACAAGCTCCAAAGTGGAATTGGCCGGCTGATTCTGAAGGAAG
AAATGAAGGCCCGGTCGAGCTCCTATGCAGATCCCTGGACCCCTCCCCGGAGCTCCACCAGCAGCCGGGAAGCCCTGCACACAGCTGGCT
ATGAGATGTCCCTCAATGGCTGCTCCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTTCCTGGCCT
CCATTCAGAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGTGATGACCGCGGCCAGCTGCTTCCAAAGCCAGA
ACCCCGGGGTTAGCACCGTGGTGCTGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCAGTCCCGCCAGACGTTTTCCATCAGCAGCATGA
GCGAGAATGGCTACGACCCCCAGCAGAACCTGAACGACCTGATGCTGCTTCAGCTGGACCGTGAGGCCAACCTCACCAGCAGCGTGACGA
TACTGCCACTGCCTCTGCAGAACGCCACGGTGGAAGCCGGCACCAGATGCCAGGTGGCCGGCTGGGGGAGCCAGCGCAGTGGGGGGCGTC
TCTCCCGTTTTCCCAGGTTTGTCAACGTGACTGTGACCCCCGAGGACCAGTGTCGCCCCAACAACGTGTGCACCGGTGTGCTCACCCGCC
GCGGTGGCATCTGCAATGGGGACGGGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCGTGGCCTCCTTTTCCCTGGGGCCCTGTG
GCCGAGGCCCTGACTTCTTCACCCGAGTGGCGCTCTTCCGAGACTGGATCGATGGTGTTCTCAACAACCCGGGACCGGGGCCAGCCTAGG
GGGGCCTGTGACCTCCCATGGAGCCCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCACCCACCTCCCACGGCCCCGCCCCTGCCCCCGC

>523_523_5_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000506113_AZU1_chr19_828230_ENST00000233997_length(amino acids)=798AA_BP=567
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICAKVDNEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI
YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSGPESGRSSPYHSQLDVRSSTPTSYQAPKHFHIPAGDSNIYRKPPIYKRH
GDLSTATKSKTSEDISQTSKYSPIYSPDPYYASESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYAD
PWTPPRSSTSSREALHTAGYEMSLNGCSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGA
YDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVT

--------------------------------------------------------------
>523_523_6_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000508983_AZU1_chr19_828230_ENST00000233997_length(transcript)=2487nt_BP=1649nt
CAGCCGGGGCCTCCGTATTGAATGAAAGACCCAGTGCAAAGACATCACCATGAACACTAGCATTCCTTATCAGCAGAATCCTTACAATCC
ACGGGGCAGCTCCAATGTCATCCAGTGCTACCGCTGTGGAGACACCTGCAAAGGGGAAGTGGTCCGCGTGCACAACAACCACTTCCACAT
CAGATGCTTCACCTGTCAAGTATGTGGCTGTGGCCTGGCCCAGTCAGGCTTCTTCTTCAAGAACCAGGAGTACATCTGCACCCAGGACTA
CCAGCAACTCTATGGCACCCGCTGTGACAGCTGCCGGGACTTCATCACAGGCGAAGTCATCTCGGCCCTGGGCCGCACTTACCACCCCAA
GTGCTTCGTGTGCAGCTTGTGCAGGAAGCCTTTCCCCATTGGAGACAAGGTGACCTTCAGCGGTAAAGAATGTGTGTGCCAAACGTGCTC
CCAGTCCATGGCCAGCAGTAAGCCCATCAAGATTCGTGGACCAAGCCACTGTGCCGGGTGCAAGGAGGAGATCAAGCACGGCCAGTCACT
CCTGGCTCTGGACAAGCAGTGGCACGTCAGCTGCTTCAAGTGCCAGACCTGCAGCGTCATCCTCACCGGGGAGTATATCAGCAAGGATGG
TGTTCCATACTGTGAGTCCGACTACCATGCCCAGTTTGGCATTAAATGTGAGACTTGTGACCGATACATCAGTGGCAGAGTCTTGGAGGC
AGGAGGGAAGCACTACCACCCAACCTGTGCCAGGTGTGTACGCTGCCACCAGATGTTCACCGAAGGAGAGGAAATGTACCTCACAGGTTC
CGAGGTTTGGCACCCCATCTGCAAACAGGCAGCCCGGGCAGAGAAGAAGTTAAAGCATAGACGGACATCTGAAACCTCCATCTCACCCCC
TGGATCCAGCATTGGGTCACCCAACCGAGTCATCTGCGCTAAAGTGGATAATGAGATCCTTAATTACAAAGACCTGGCGGCTCTCCCCAA
GGTTAAGTCTATCTACGAGGTACAACGCCCCGACCTCATTTCCTATGAGCCTCATTCCAGATACATGTCCGACGAGATGCTGGAGAGATG
TGGCTATGGAGAGTCGCTGGGAACATTATCTCCCTACTCCCAGGACATCTACGAGAACCTGGACCTCCGGCAGAGACGGGCCTCCAGCCC
GGGGTACATAGACTCCCCCACCTACAGCCGGCAGGGCATGTCCCCCACCTTCTCCCGCTCACCTCACCACTACTACCGCTCTGCTGGAGA
CAGTAACATCTACCGGAAACCCCCGATCTACAAACGGCATGGTGATTTGTCTACAGCAACCAAGAGCAAAACAAGTGAAGACATCAGCCA
GACCTCCAAGTACAGTCCCATCTACTCGCCAGACCCCTACTATGCTTCGGAGTCTGAGTACTGGACCTACCATGGGTCCCCCAAAGTGCC
CCGAGCCAGAAGGTTCTCGTCTGGAGGAGAGGAGGATGATTTTGACCGCAGCATGCACAAGCTCCAAAGTGGAATTGGCCGGCTGATTCT
GAAGGAAGAAATGAAGGCCCGGTCGAGCTCCTATGCAGATCCCTGGACCCCTCCCCGGAGCTCCACCAGCAGCCGGGAAGCCCTGCACAC
AGCTGGCTATGAGATGTCCCTCAATGGCTGCTCCAGCCCCCTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTT
CCTGGCCTCCATTCAGAATCAAGGCAGGCACTTCTGCGGGGGTGCCCTGATCCATGCCCGCTTCGTGATGACCGCGGCCAGCTGCTTCCA
AAGCCAGAACCCCGGGGTTAGCACCGTGGTGCTGGGTGCCTATGACCTGAGGCGGCGGGAGAGGCAGTCCCGCCAGACGTTTTCCATCAG
CAGCATGAGCGAGAATGGCTACGACCCCCAGCAGAACCTGAACGACCTGATGCTGCTTCAGCTGGACCGTGAGGCCAACCTCACCAGCAG
CGTGACGATACTGCCACTGCCTCTGCAGAACGCCACGGTGGAAGCCGGCACCAGATGCCAGGTGGCCGGCTGGGGGAGCCAGCGCAGTGG
GGGGCGTCTCTCCCGTTTTCCCAGGTTTGTCAACGTGACTGTGACCCCCGAGGACCAGTGTCGCCCCAACAACGTGTGCACCGGTGTGCT
CACCCGCCGCGGTGGCATCTGCAATGGGGACGGGGGCACCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCGTGGCCTCCTTTTCCCTGGG
GCCCTGTGGCCGAGGCCCTGACTTCTTCACCCGAGTGGCGCTCTTCCGAGACTGGATCGATGGTGTTCTCAACAACCCGGGACCGGGGCC
AGCCTAGGGGGGCCTGTGACCTCCCATGGAGCCCAGCCCCGCCCTCCACACCTCCGGCGCTCCGCACCCACCTCCCACGGCCCCGCCCCT

>523_523_6_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000508983_AZU1_chr19_828230_ENST00000233997_length(amino acids)=765AA_BP=534
MNTSIPYQQNPYNPRGSSNVIQCYRCGDTCKGEVVRVHNNHFHIRCFTCQVCGCGLAQSGFFFKNQEYICTQDYQQLYGTRCDSCRDFIT
GEVISALGRTYHPKCFVCSLCRKPFPIGDKVTFSGKECVCQTCSQSMASSKPIKIRGPSHCAGCKEEIKHGQSLLALDKQWHVSCFKCQT
CSVILTGEYISKDGVPYCESDYHAQFGIKCETCDRYISGRVLEAGGKHYHPTCARCVRCHQMFTEGEEMYLTGSEVWHPICKQAARAEKK
LKHRRTSETSISPPGSSIGSPNRVICAKVDNEILNYKDLAALPKVKSIYEVQRPDLISYEPHSRYMSDEMLERCGYGESLGTLSPYSQDI
YENLDLRQRRASSPGYIDSPTYSRQGMSPTFSRSPHHYYRSAGDSNIYRKPPIYKRHGDLSTATKSKTSEDISQTSKYSPIYSPDPYYAS
ESEYWTYHGSPKVPRARRFSSGGEEDDFDRSMHKLQSGIGRLILKEEMKARSSSYADPWTPPRSSTSSREALHTAGYEMSLNGCSSPLLD
IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDL
MLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLV

--------------------------------------------------------------
>523_523_7_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000517451_AZU1_chr19_828230_ENST00000233997_length(transcript)=2719nt_BP=1881nt
CTAAGCCTCGATTGAAGGAGCACATCCCTTCCATTGAAGCTGCAGAGGAGCAGCTGCCACCCTGTGCACCCACACTTGCTTAAGGGTCTA
GCTGGATAACAAAAGGAGGCCCAGAATCGGTGGAGCTTGGAGATGAGCGAAGCAGTCCTGCACCAGGTTCTGAACTAATTAGCTGGTGGA
GGGGACAATACGAGTTTAAACAGCGGCTCTGGGTGCCTAAGATTCTACATTTTATACAGACATCCTTGGTTCCAGAGGGGGCTGAGCAGG
GGGGTCCGAGGTGAGTCTGTGAGCATGTGCAAGTCTGTACCAGCTTGTGAAGGACATGCCATGTCCCCTGAGTACTCATAGAAAGACACC
AACATGACAAAGGTAGTTTGGCTTTATACCTAGAAAAGGCCCCCAGGTCACAAGCTTCTCAGGACTTTGTGGGATTTTCCAGGTGGGCCC
TGAGGGGTGGCACTAAAGCAGACTCAAGAGGAGTCTGGGGTGGAGGTGGGTTGCTTGGAAAAGAGGGCGGAGGAAAAAGCTAAATGCAGT
CAGCCAGGAGGGGCTGCCCAGGACCCAAGTCAAAGAGAAGAATTTGAAAGCTTTGGAAGCAAGTGCTGTTGTGGGGGCTGCATAGCCCAG
GGCTGGCTGAAGCTGATCCACCACGCTCTGCCACTCTGGCTCCACAGAGCACAGAGCTTGTCCCTAAAGCTTCCTGTAGCTGACCATGAG
AAATGGTCATGCAGCCACACACACTTCCCCAGCCCCTCTCTCTGCTCTACCAGCCTGTCACCCACGTTTGGGCCACGAGAAGTCACTGCT
CTGTAAGTAGTTGTGACTGCAGTGGGTCTTTTTGGTCACCCCTGTCCTGGGCTTACTTCAGGTGGAAGCTTGAAGCTGGATGGCAGCTGA
GCCAGCAGACCGATTCTGACACTTACAGATGAGGAAACTAAGGCAGAGATGGTAGGACCTGCCCAGTGTTACAGCTGAGTAAAGTGGCAG
AGCTGGGACCAGAACCCAGGTTTGCTGACTCCCTGTCTAGCACTCCTTCCTTCAGGCTATGTAGTCCCTGAGCAGAATGTGGCATCTCAG
GTTGTGAGAAATGATGGAGTTCAAATTTATAACAAGGAAGGCTTCTAAAGGGCTAGGAAGGCTTCTAAAGGGCTGGGGCTCACCTGGGAC
CTGTCCAGTCTTATTTGAGGAGCCACACCCTTAGAGGTCATTCTGGAACAGACCTGGGAATCCATGGAATGTGCTGGAAAGAGCCCTGGG
CTGGGATCTGGTCCAGTTCTGGTGCTCACATGCTATGTGGTCTTAAGCAAGCCCCTTCCCCTCTCTGGTGCTCCAATTACTAAATGCAAA
ATGAGGGTTTGGCCCCAGTGCTTTTCCAGCTCCGATGCTCCATGGCCCAGTTCTAACAGAGAGCCCTGATCTTGAAGTGGACTCACTCCC
CTGGGCTGGAGCCTGGTAAAGATAGGAAAAGGGTACACAGTCCCATCCCGGTCACTCTGCCTTCCTGAAGTGCTCTCCTTGGGTCCTCTG
CAGGTGATTTGTCTACAGCAACCAAGAGCAAAACAAGTGAAGACATCAGCCAGACCTCCAAGTACAGTCCCATCTACTCGCCAGACCCCT
ACTATGCTTCGGAGTCTGAGTACTGGACCTACCATGGGTCCCCCAAAGTGCCCCGAGCCAGAAGGTTCTCGTCTGGAGGAGAGGAGGATG
ATTTTGACCGCAGCATGCACAAGCTCCAAAGTGGAATTGGCCGGCTGATTCTGAAGGAAGAAATGAAGGCCCGGTCGAGCTCCTATGCAG
ATCCCTGGACCCCTCCCCGGAGCTCCACCAGCAGCCGGGAAGCCCTGCACACAGCTGGCTATGAGATGTCCCTCAATGGCTGCTCCAGCC
CCCTTTTGGACATCGTTGGCGGCCGGAAGGCGAGGCCCCGCCAGTTCCCGTTCCTGGCCTCCATTCAGAATCAAGGCAGGCACTTCTGCG
GGGGTGCCCTGATCCATGCCCGCTTCGTGATGACCGCGGCCAGCTGCTTCCAAAGCCAGAACCCCGGGGTTAGCACCGTGGTGCTGGGTG
CCTATGACCTGAGGCGGCGGGAGAGGCAGTCCCGCCAGACGTTTTCCATCAGCAGCATGAGCGAGAATGGCTACGACCCCCAGCAGAACC
TGAACGACCTGATGCTGCTTCAGCTGGACCGTGAGGCCAACCTCACCAGCAGCGTGACGATACTGCCACTGCCTCTGCAGAACGCCACGG
TGGAAGCCGGCACCAGATGCCAGGTGGCCGGCTGGGGGAGCCAGCGCAGTGGGGGGCGTCTCTCCCGTTTTCCCAGGTTTGTCAACGTGA
CTGTGACCCCCGAGGACCAGTGTCGCCCCAACAACGTGTGCACCGGTGTGCTCACCCGCCGCGGTGGCATCTGCAATGGGGACGGGGGCA
CCCCCCTCGTCTGCGAGGGCCTGGCCCACGGCGTGGCCTCCTTTTCCCTGGGGCCCTGTGGCCGAGGCCCTGACTTCTTCACCCGAGTGG
CGCTCTTCCGAGACTGGATCGATGGTGTTCTCAACAACCCGGGACCGGGGCCAGCCTAGGGGGGCCTGTGACCTCCCATGGAGCCCAGCC
CCGCCCTCCACACCTCCGGCGCTCCGCACCCACCTCCCACGGCCCCGCCCCTGCCCCCGCTCCGGCCAGAGGGGCCCTGGCTGTAATAAA

>523_523_7_ABLIM3-AZU1_ABLIM3_chr5_148627492_ENST00000517451_AZU1_chr19_828230_ENST00000233997_length(amino acids)=355AA_BP=1
MVLGGHSHVDKPGKTGETPPTALAPPAGHLASGAGFHRGVLQRQWQYRHAAGEVGLTVQLKQHQVVQVLLGVVAILAHAADGKRLAGLPL
PPPQVIGTQHHGANPGVLALEAAGRGHHEAGMDQGTPAEVPALILNGGQERELAGPRLPAANDVQKGAGAAIEGHLIASCVQGFPAAGGA
PGRGPGICIGARPGLHFFLQNQPANSTLELVHAAVKIILLSSRREPSGSGHFGGPMVGPVLRLRSIVGVWRVDGTVLGGLADVFTCFALG

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Fusion Gene PPI Analysis for ABLIM3-AZU1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for ABLIM3-AZU1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ABLIM3-AZU1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source