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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MCU-NFIX (FusionGDB2 ID:52326)

Fusion Gene Summary for MCU-NFIX

check button Fusion gene summary
Fusion gene informationFusion gene name: MCU-NFIX
Fusion gene ID: 52326
HgeneTgene
Gene symbol

MCU

NFIX

Gene ID

90550

4784

Gene namemitochondrial calcium uniporternuclear factor I X
SynonymsC10orf42|CCDC109A|HsMCUCTF|MRSHSS|NF-I/X|NF1-X|NF1A|SOTOS2
Cytomap

10q22.1

19p13.13

Type of geneprotein-codingprotein-coding
Descriptioncalcium uniporter protein, mitochondrialcoiled-coil domain-containing protein 109Anuclear factor 1 X-typeCCAAT-box-binding transcription factorTGGCA-binding proteinnuclear factor 1/X
Modification date2020031320200329
UniProtAcc

Q8NE86

Q14938

Ensembl transtripts involved in fusion geneENST00000357157, ENST00000373053, 
ENST00000536019, ENST00000605416, 
ENST00000358552, ENST00000587260, 
ENST00000588228, ENST00000588680, 
ENST00000360105, ENST00000397661, 
ENST00000585575, ENST00000587760, 
ENST00000592199, 
Fusion gene scores* DoF score9 X 6 X 4=21622 X 13 X 10=2860
# samples 1026
** MAII scorelog2(10/216*10)=-1.11103131238874
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(26/2860*10)=-3.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MCU [Title/Abstract] AND NFIX [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMCU(74452059)-NFIX(13135835), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMCU

GO:0006851

mitochondrial calcium ion transmembrane transport

21685888|24560927

HgeneMCU

GO:0019722

calcium-mediated signaling

21685886|21685888

HgeneMCU

GO:0036444

calcium import into the mitochondrion

22925203

HgeneMCU

GO:0051259

protein complex oligomerization

21685886

HgeneMCU

GO:0051561

positive regulation of mitochondrial calcium ion concentration

21685888|24560927

TgeneNFIX

GO:0000122

negative regulation of transcription by RNA polymerase II

19706729

TgeneNFIX

GO:0045944

positive regulation of transcription by RNA polymerase II

19706729


check buttonFusion gene breakpoints across MCU (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NFIX (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E9-A1RH-01AMCUchr10

74452059

-NFIXchr19

13135835

+
ChimerDB4BRCATCGA-E9-A1RH-01AMCUchr10

74452059

+NFIXchr19

13135835

+


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Fusion Gene ORF analysis for MCU-NFIX

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000357157ENST00000358552MCUchr10

74452059

+NFIXchr19

13135835

+
5CDS-5UTRENST00000357157ENST00000587260MCUchr10

74452059

+NFIXchr19

13135835

+
5CDS-5UTRENST00000357157ENST00000588228MCUchr10

74452059

+NFIXchr19

13135835

+
5CDS-5UTRENST00000373053ENST00000358552MCUchr10

74452059

+NFIXchr19

13135835

+
5CDS-5UTRENST00000373053ENST00000587260MCUchr10

74452059

+NFIXchr19

13135835

+
5CDS-5UTRENST00000373053ENST00000588228MCUchr10

74452059

+NFIXchr19

13135835

+
5CDS-intronENST00000357157ENST00000588680MCUchr10

74452059

+NFIXchr19

13135835

+
5CDS-intronENST00000373053ENST00000588680MCUchr10

74452059

+NFIXchr19

13135835

+
In-frameENST00000357157ENST00000360105MCUchr10

74452059

+NFIXchr19

13135835

+
In-frameENST00000357157ENST00000397661MCUchr10

74452059

+NFIXchr19

13135835

+
In-frameENST00000357157ENST00000585575MCUchr10

74452059

+NFIXchr19

13135835

+
In-frameENST00000357157ENST00000587760MCUchr10

74452059

+NFIXchr19

13135835

+
In-frameENST00000357157ENST00000592199MCUchr10

74452059

+NFIXchr19

13135835

+
In-frameENST00000373053ENST00000360105MCUchr10

74452059

+NFIXchr19

13135835

+
In-frameENST00000373053ENST00000397661MCUchr10

74452059

+NFIXchr19

13135835

+
In-frameENST00000373053ENST00000585575MCUchr10

74452059

+NFIXchr19

13135835

+
In-frameENST00000373053ENST00000587760MCUchr10

74452059

+NFIXchr19

13135835

+
In-frameENST00000373053ENST00000592199MCUchr10

74452059

+NFIXchr19

13135835

+
intron-3CDSENST00000536019ENST00000360105MCUchr10

74452059

+NFIXchr19

13135835

+
intron-3CDSENST00000536019ENST00000397661MCUchr10

74452059

+NFIXchr19

13135835

+
intron-3CDSENST00000536019ENST00000585575MCUchr10

74452059

+NFIXchr19

13135835

+
intron-3CDSENST00000536019ENST00000587760MCUchr10

74452059

+NFIXchr19

13135835

+
intron-3CDSENST00000536019ENST00000592199MCUchr10

74452059

+NFIXchr19

13135835

+
intron-3CDSENST00000605416ENST00000360105MCUchr10

74452059

+NFIXchr19

13135835

+
intron-3CDSENST00000605416ENST00000397661MCUchr10

74452059

+NFIXchr19

13135835

+
intron-3CDSENST00000605416ENST00000585575MCUchr10

74452059

+NFIXchr19

13135835

+
intron-3CDSENST00000605416ENST00000587760MCUchr10

74452059

+NFIXchr19

13135835

+
intron-3CDSENST00000605416ENST00000592199MCUchr10

74452059

+NFIXchr19

13135835

+
intron-5UTRENST00000536019ENST00000358552MCUchr10

74452059

+NFIXchr19

13135835

+
intron-5UTRENST00000536019ENST00000587260MCUchr10

74452059

+NFIXchr19

13135835

+
intron-5UTRENST00000536019ENST00000588228MCUchr10

74452059

+NFIXchr19

13135835

+
intron-5UTRENST00000605416ENST00000358552MCUchr10

74452059

+NFIXchr19

13135835

+
intron-5UTRENST00000605416ENST00000587260MCUchr10

74452059

+NFIXchr19

13135835

+
intron-5UTRENST00000605416ENST00000588228MCUchr10

74452059

+NFIXchr19

13135835

+
intron-intronENST00000536019ENST00000588680MCUchr10

74452059

+NFIXchr19

13135835

+
intron-intronENST00000605416ENST00000588680MCUchr10

74452059

+NFIXchr19

13135835

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000373053MCUchr1074452059+ENST00000397661NFIXchr1913135835+3057171211469482
ENST00000373053MCUchr1074452059+ENST00000592199NFIXchr1913135835+1653171211652543
ENST00000373053MCUchr1074452059+ENST00000587760NFIXchr1913135835+1614171211469482
ENST00000373053MCUchr1074452059+ENST00000585575NFIXchr1913135835+1653171211652543
ENST00000373053MCUchr1074452059+ENST00000360105NFIXchr1913135835+5529171211346441
ENST00000357157MCUchr1074452059+ENST00000397661NFIXchr1913135835+304515991457482
ENST00000357157MCUchr1074452059+ENST00000592199NFIXchr1913135835+164115991640543
ENST00000357157MCUchr1074452059+ENST00000587760NFIXchr1913135835+160215991457482
ENST00000357157MCUchr1074452059+ENST00000585575NFIXchr1913135835+164115991640543
ENST00000357157MCUchr1074452059+ENST00000360105NFIXchr1913135835+551715991334441

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000373053ENST00000397661MCUchr1074452059+NFIXchr1913135835+0.048635780.95136416
ENST00000373053ENST00000592199MCUchr1074452059+NFIXchr1913135835+0.0466669870.953333
ENST00000373053ENST00000587760MCUchr1074452059+NFIXchr1913135835+0.062927190.93707275
ENST00000373053ENST00000585575MCUchr1074452059+NFIXchr1913135835+0.0466669870.953333
ENST00000373053ENST00000360105MCUchr1074452059+NFIXchr1913135835+0.0175740160.9824259
ENST00000357157ENST00000397661MCUchr1074452059+NFIXchr1913135835+0.049197060.9508029
ENST00000357157ENST00000592199MCUchr1074452059+NFIXchr1913135835+0.0470436630.9529564
ENST00000357157ENST00000587760MCUchr1074452059+NFIXchr1913135835+0.063112670.9368873
ENST00000357157ENST00000585575MCUchr1074452059+NFIXchr1913135835+0.0470436630.9529564
ENST00000357157ENST00000360105MCUchr1074452059+NFIXchr1913135835+0.0175319240.98246807

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Fusion Genomic Features for MCU-NFIX


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MCU-NFIX


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:74452059/chr19:13135835)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MCU

Q8NE86

NFIX

Q14938

FUNCTION: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria (PubMed:21685888, PubMed:21685886, PubMed:23101630, PubMed:22904319, PubMed:23178883, PubMed:22829870, PubMed:22822213, PubMed:24332854, PubMed:23755363, PubMed:26341627). Constitutes the pore-forming and calcium-conducting subunit of the uniporter complex (uniplex) (PubMed:23755363). Activity is regulated by MICU1 and MICU2. At low Ca(2+) levels MCU activity is down-regulated by MICU1 and MICU2; at higher Ca(2+) levels MICU1 increases MCU activity (PubMed:24560927, PubMed:26903221). Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. Involved in buffering the amplitude of systolic calcium rises in cardiomyocytes (PubMed:22822213). While dispensable for baseline homeostatic cardiac function, acts as a key regulator of short-term mitochondrial calcium loading underlying a 'fight-or-flight' response during acute stress: acts by mediating a rapid increase of mitochondrial calcium in pacemaker cells (PubMed:25603276). participates in mitochondrial permeability transition during ischemia-reperfusion injury (By similarity). Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake (PubMed:22904319, PubMed:22829870). Mitochondrial calcium uptake in skeletal muscle cells is involved in muscle size in adults (By similarity). Regulates synaptic vesicle endocytosis kinetics in central nerve terminal (By similarity). Involved in antigen processing and presentation (By similarity). {ECO:0000250|UniProtKB:Q3UMR5, ECO:0000269|PubMed:21685886, ECO:0000269|PubMed:21685888, ECO:0000269|PubMed:22822213, ECO:0000269|PubMed:22829870, ECO:0000269|PubMed:22904319, ECO:0000269|PubMed:23101630, ECO:0000269|PubMed:23178883, ECO:0000269|PubMed:23755363, ECO:0000269|PubMed:24332854, ECO:0000269|PubMed:24560927, ECO:0000269|PubMed:25603276, ECO:0000269|PubMed:26341627, ECO:0000269|PubMed:26903221}.FUNCTION: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNFIXchr10:74452059chr19:13135835ENST000005855750111_1941495.0DNA bindingCTF/NF-I
TgeneNFIXchr10:74452059chr19:13135835ENST00000587260091_1940281.6666666666667DNA bindingCTF/NF-I
TgeneNFIXchr10:74452059chr19:13135835ENST000005877600101_1941460.6666666666667DNA bindingCTF/NF-I
TgeneNFIXchr10:74452059chr19:13135835ENST00000397661010398_4069878.6666666666666Motif9aaTAD
TgeneNFIXchr10:74452059chr19:13135835ENST00000585575011398_4061495.0Motif9aaTAD
TgeneNFIXchr10:74452059chr19:13135835ENST0000058726009398_4060281.6666666666667Motif9aaTAD
TgeneNFIXchr10:74452059chr19:13135835ENST00000587760010398_4061460.6666666666667Motif9aaTAD
TgeneNFIXchr10:74452059chr19:13135835ENST00000592199011398_4069503.0Motif9aaTAD

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMCUchr10:74452059chr19:13135835ENST00000357157+18192_22350331.0Coiled coilOntology_term=ECO:0000255
HgeneMCUchr10:74452059chr19:13135835ENST00000357157+18311_33950331.0Coiled coilOntology_term=ECO:0000255
HgeneMCUchr10:74452059chr19:13135835ENST00000373053+18192_22350352.0Coiled coilOntology_term=ECO:0000255
HgeneMCUchr10:74452059chr19:13135835ENST00000373053+18311_33950352.0Coiled coilOntology_term=ECO:0000255
HgeneMCUchr10:74452059chr19:13135835ENST00000536019+18192_2230303.0Coiled coilOntology_term=ECO:0000255
HgeneMCUchr10:74452059chr19:13135835ENST00000536019+18311_3390303.0Coiled coilOntology_term=ECO:0000255
HgeneMCUchr10:74452059chr19:13135835ENST00000357157+18216_23450331.0RegionOuter juxtamembrane helix (OJMH)
HgeneMCUchr10:74452059chr19:13135835ENST00000357157+18283_29250331.0RegionInner juxtamembrane helix (IJMH)
HgeneMCUchr10:74452059chr19:13135835ENST00000357157+1875_16550331.0RegionN-terminal MCU domain
HgeneMCUchr10:74452059chr19:13135835ENST00000373053+18216_23450352.0RegionOuter juxtamembrane helix (OJMH)
HgeneMCUchr10:74452059chr19:13135835ENST00000373053+18283_29250352.0RegionInner juxtamembrane helix (IJMH)
HgeneMCUchr10:74452059chr19:13135835ENST00000373053+1875_16550352.0RegionN-terminal MCU domain
HgeneMCUchr10:74452059chr19:13135835ENST00000536019+18216_2340303.0RegionOuter juxtamembrane helix (OJMH)
HgeneMCUchr10:74452059chr19:13135835ENST00000536019+18283_2920303.0RegionInner juxtamembrane helix (IJMH)
HgeneMCUchr10:74452059chr19:13135835ENST00000536019+1875_1650303.0RegionN-terminal MCU domain
HgeneMCUchr10:74452059chr19:13135835ENST00000357157+18257_26550331.0Topological domainMitochondrial intermembrane
HgeneMCUchr10:74452059chr19:13135835ENST00000357157+18284_35150331.0Topological domainMitochondrial matrix
HgeneMCUchr10:74452059chr19:13135835ENST00000357157+1851_23350331.0Topological domainMitochondrial matrix
HgeneMCUchr10:74452059chr19:13135835ENST00000373053+18257_26550352.0Topological domainMitochondrial intermembrane
HgeneMCUchr10:74452059chr19:13135835ENST00000373053+18284_35150352.0Topological domainMitochondrial matrix
HgeneMCUchr10:74452059chr19:13135835ENST00000373053+1851_23350352.0Topological domainMitochondrial matrix
HgeneMCUchr10:74452059chr19:13135835ENST00000536019+18257_2650303.0Topological domainMitochondrial intermembrane
HgeneMCUchr10:74452059chr19:13135835ENST00000536019+18284_3510303.0Topological domainMitochondrial matrix
HgeneMCUchr10:74452059chr19:13135835ENST00000536019+1851_2330303.0Topological domainMitochondrial matrix
HgeneMCUchr10:74452059chr19:13135835ENST00000357157+18234_25650331.0TransmembraneHelical
HgeneMCUchr10:74452059chr19:13135835ENST00000357157+18266_28350331.0TransmembraneHelical
HgeneMCUchr10:74452059chr19:13135835ENST00000373053+18234_25650352.0TransmembraneHelical
HgeneMCUchr10:74452059chr19:13135835ENST00000373053+18266_28350352.0TransmembraneHelical
HgeneMCUchr10:74452059chr19:13135835ENST00000536019+18234_2560303.0TransmembraneHelical
HgeneMCUchr10:74452059chr19:13135835ENST00000536019+18266_2830303.0TransmembraneHelical
TgeneNFIXchr10:74452059chr19:13135835ENST000003976610101_1949878.6666666666666DNA bindingCTF/NF-I
TgeneNFIXchr10:74452059chr19:13135835ENST000005921990111_1949503.0DNA bindingCTF/NF-I


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Fusion Gene Sequence for MCU-NFIX


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>52326_52326_1_MCU-NFIX_MCU_chr10_74452059_ENST00000357157_NFIX_chr19_13135835_ENST00000360105_length(transcript)=5517nt_BP=159nt
AGTTGAGAGATGGCGGCCGCCGCAGGTAGATCGCTCCTGCTGCTCCTCTCCTCTCGGGGCGGCGGCGGCGGGGGCGCCGGCGGCTGCGGG
GCGCTGACTGCCGGCTGCTTCCCTGGGCTGGGCGTCAGCCGCCACCGGCAGCAGCAGCACCACCGGACGGATGAGTTCCACCCGTTCATC
GAGGCACTGCTGCCTCACGTCCGCGCTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAGAAGCATGAAAAG
CGGATGTCGAAGGACGAGGAGCGGGCGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCATCCCGGCTGCTG
GCCAAGCTGCGCAAGGACATCCGGCCCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGCTGCGTGCTCTCC
AACCCCGACCAGAAGGGCAAGATCCGGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTCATGGTGATTTTG
TTTAAGGGGATCCCCCTGGAAAGTACTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGCGTCCAGCCACAT
CACATTGGAGTCACAATCAAAGAACTGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGATAGTTCAAACCAG
CAAGGAGATGCGGACATCAAACCACTGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGGAATGTGACGGAG
CTGGTGAGAGTATCACAGACTCCTGTTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGCTACTACAACATC
AACCAGGTGACCCTGGGGCGGCGGTCCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGATGACAGTGAGATG
GAGAGCCCTGTTGATGACGTGTTCTATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGGCCCAACGATGTG
GATGCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCCTCCACGTCCATCATCCAGCAGTCGAGCCCGTATTTCACGCACCCG
ACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAGTTTGTGCAGTTTGTGTGCTCGGATGGCTCGGGCCAGGCCACCGGA
CAGCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCAGCATCGGACCCCGGGACGGCAACTTTCTGAACATCCCACAGCAGT
CTCAGTCCTGGTTCCTCTGATAAGATCGACAAAAGAAACAACAAAATGAGAAGAAGAGGTTCCTCGAAAGGGGGGAGAAGAAATTTTGAG
AATGGAAAAATCCCCCAGCCCAGCCCAGCCCCACCGAAAAGCAAAAATTACACGTCGTCAGCCACTCAGCCCTTCTCTCCTCCAGCCCGG
GGACCCCCGCGGGCCCCAGAAGCAGCCCAGTTCTCAGAGAGCCCTTGGAAGGGGTCTCGGTGGAGCTGTGCACCAGCAGCCAAGCAGAAA
GAAACACGCGACATGGACTCTGTCAAGTAGAGGACAGAAAGCAAGAAAGGATGCAGAACTGCCTTCCTCCCCCTGACCCCGCCCCGGCCT
TCTGGGGAAGGAACAAAGTCCCCAAACAAAGCAACCAGCACAATTCTGAAGGGGCCTGGCCTCCACCCTCACCCCTTCCTAGGGGAACCC
CACCCTCCACACAGCCGGAGCTGCCCTAGGGAGCCTGGAGGGCCAGCTTGTAAAGATGATGGGGTTTAGATCCCTCAGGCTCTCCCCTCC
AGACTCCGCCCTTCCCTCCCTCCCTCCCTCCCTCCCTCTCTGCCAAGGCTCCAGCTTCTTCCCCCAGCTGCTCCCGACCAGGAGGGGGAG
AGCAGCCTCCACTTACCCCACCCCACCCTTGGGCTAAAAGCCCCCAGGCGGGCAGGGGGTGACCCCTGGAGCTAGTTGCGTGTCCCAGAA
TGGAGGGTGTTCTGACACCCCACCCTGAGCCGCAAGAGCAGTCCTGGGGCCCTGGACCCCTCTGTACAGTCCGTAGGAAAAAGTCGGAAT
GCTCTCGACGGCCTCGTCCCAGCCTGGGACAGGCCCCCTTTCCCCTCTCTCTGCAGGCCAGGAGGGCCTCCTTCCTGCCACGAGGGAGGG
GAGTCGGGCCCCAGGTCGCCCCCGCCCCCAGCCCTGCATGCAGGTGCCCTCGCTCCGCCCCATCAGTTCCTGCCCCTGCCCCTCATGCAG
ACTGCCCTGCTGGGGCCGGGCCGGAGGGTGGAGCAGAAAGGGGACCCCGGAGCCGAGCGAGGAGGACCAGGCAGCCGCCGCTGCCGCGCT
AAGCCACCACCTGCGCTTAGGTAGGCGTCCTGCTCGCCGACTTTCAGTTCCTTGGGAGGGTGTTGGGTGTCGTCCTTTTCAAAAGTGTTT
TGGAGCTTTCTGTGCCCCCCGACTTTCCCCCGCCTCCCCGCCCCCCACGTGGCCACTTTTCTCTGGATTTTAGCTGTAATGTCTTTACTC
TTTATTTAGGGGTGGGGCATTCATTGTTTGGGTCTTTTGCTGTTGGAATGGGAACTCCTCCTCCATTTGAGCAACTTGGGAACAATTTGG
TAACACACCACAGGAAGTAGCTCTCCCCCCCAGCCCCCTCCTCCCTCAAGGGAGGGTTGGGGGGCCTGTCCAGAGGGTCTTCAGAAGCCC
CCCTGGGAGGGAGGGGAGGATGAGCACGCCCAGCTCCCCTCCAGGGTGTGACTTGGCCCCTCTGGCTTGTCTTTCTGTGCCTTACTCCTC
CTCCTGCGTCTCCCGTTCCTGGCCCCTTCTTGAGTCCTTGTGCCTCTCTCTTTCTCTCTCTTTCTTAATTGTATGAAAACACAAAGCACA
GGTCAGGATCCTCTGAGAGAAAATCAACATTGCACCACGTAGGGGTGGGCTATGGGCTGTATTTATTGTGAATCTAGTTTGTGAGGCTGT
GGCCCCGAGCTGGCGGAGGGAGGGAAGAGGAGGGAGTGACGGGAGGGGAGGAGGTCAGCGACCTGGGGCCGTAGCGGCAGGCGAACGGTG
CCTGCTACCCAGCTGGAAGCCACAAGGTGGCTGGCTCCAGGGGCGGCTTTTGTTGGAAGTTGAGTGAAGCCCTCCCCCTGTCCTCAGCGT
GCAGCCCTAGAGGACCCCAGGGCTGAGGGGCAGTGGATCCTGCGGGAGTCTCCCGGGGCGTGGGGAGTAAGGCCCCGGGGGTGGGGGGCC
GGGTGGGCCGGGCGTGACGCGCGGTCAAAGTGCAATGATTTTTCAGTTCGGTTGGCTAAACAGGGTCAGAGCTGAGAGCGAAGCAGAAGG
GGCTCCCTGTCCGGCCCACGTGCCCTTTCCCTCGACGACAGTCGAGGGCTCGGGCTCTGTGGGACTGTGGGAGCTAGGGTCTGCGGGGCG
CCTGCCCGGGCGAGGTCGGAAGCTGCAGGCCAGCTGGGCCCGGGCCGGAGCGTGCCCGGCGGGGCTGCCCGGGCGGGCAGGGGGTGGGGG
CTGCTCCTTTCCCAAGTGGTGTTGTGAGGGGCAATGAGGGCAACAGGAGATGTGGGGACGTGTTAGGAGAGAAAAAAAAAAAAACAAAAA
TATATATGGGGGAAATTAACTTTTTTTTTTCATTGAACCAAGTGCAATGCATCAGAGAGTTTTCCTATCTTTGTATGTTAAGAGATTAAG
AAAAAAAAATTCTATTTTTGTTGTAATGTCCTCGCGGCTCTGGGGACGCTAAAAGAACCGGGCCTGCCCCGCCCTGCGCGGGGATAACGA
AAGCTGAGTGTTTTTCCCTTTTTTTTGTTCGTTTTTAGTTTTTTTTTTTTTAAGTCGTTTTCCTGCGTTGACGAGGATGATCTGGGGTTT
TTATTTGTTTCGTCGTTCGTTCTGTTTCGGTGGGAGGGCTGAAGGAAACGTTCACATTTTAGAGTTTAAAAAAAACACCTCGACATTTAA
AAAATCAACCAACACAAGATCAAAAAGGAAAAGGACGAGAGAAAAATTATTTTTAAGATAATTAAACATAAAACCCTGGTGCTTCTTACA
TTATAAAGTACGTTTTAAAGAACCCACAAACTATTATACATAAGTTTATGAATCAATTAAATATCCTGCACTTGTTAGGAATACGCATAT
CCCTTCTTTGTTGAGTTTAACGGAACGGGACAGCGGCGTGCCCCCGGCGGCTGGACTGCTCCGGCCGCGGGTCTCCCCGGGCGCCCCTCC
CTGGGGCCCAGCACCCCTCCTCGCCCCATCCCCGTCCGGGTACGGGGGCGCGGCAGGGGTCCCCGGCCCCTCCCCCGCAGAGGTCAATGC
CAACGAACAAACGTCCCCTCCCTCCCTCCCTCTCCGCCCCGAGCGCCCTTCTTTGAGCCAGACGCCAACTTGACCCTCACCAGCATTATC
AGGAGCGCGCTCAGCAAGTTGGTAGTTTCCTCCCCCCTTTCCCGGCGCCCCTCCCGCCCCCATTCAACATCTCTCATCCTATCCCCGACC
CCCTCCGGGGAACACCGGGAAGGCTCGACGCTCCAGGACAGGACCAGCCACGCAGACAGGTCGATTTGCCCAGGCCCGCGCCCGCACGCA
CGCACGCACACGGCCCCGCACACAGCCCCGCCCCACCCCGCAACCAGCCCTGTCGACTGCCTTATACACCCGCCCCCGCGCTGGCCGGCC
GACCTAGTGCCTTGTTCTCACCCCCGTGCTGGCGGAGCGGACGCCGCGCTCTGGGTCCCAGAGGGGCCGGGTGGCTCAGACGACCCACCA
CTCCCCCACCCTGACCGTGCTGAACAGACCCCCCCACACGAGAGAAAATAAAGGAGCAATAAAGTCACGAGAACTTTCGTCCCCCAATCG
AGAGCCCGAGGGGCACCCCAGCCCCGCCTCTGCTCCCCCCCACCCCACCCACCCTCGGGGCGCCCCCCTCCCCCCGCAAGCCAGCCTGGG
CCAGCCCCGCTTCGGCCCCTCCCGGGAGATCCGTGCGCCCGACCAGCACCAGCATCGCGGACCGCAAAGGCCGCCCGTCCCGTCAAACAA
GTTTCTTCTTAGGCTAAGAAACGCAGTATATACGAGTATCTCTATATATAGTACTAATGGATTTGGTGTGCTTCCCCCTTAGCGTCCCCC
TCCCTCTGCTCCTCCTCCTTCAGCCTGGTCTCCCCCTCTTCTCTGCCCTCCACCCCCGTCTCTGCACTGAGATACATAAGAAACAAGGGT
AGTTTACTGTCTGTTTTGTTTTCTGGGTTTTCAGTGTCCTAGCGGAATGCAAGTAGGCAGCCAGCCCGTCTGTTCCCTCTCCGCCCCGCC
CCGCCCCGCCCCCGTCACTGCGCTTCTGTTATACCATCTTTGCCTGACTCTCTCCGGCTTCTCCATTGAATGGCTAATGTGTATGTGAAA

>52326_52326_1_MCU-NFIX_MCU_chr10_74452059_ENST00000357157_NFIX_chr19_13135835_ENST00000360105_length(amino acids)=441AA_BP=15
MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMS
KDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKG
IPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVR
VSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAG

--------------------------------------------------------------
>52326_52326_2_MCU-NFIX_MCU_chr10_74452059_ENST00000357157_NFIX_chr19_13135835_ENST00000397661_length(transcript)=3045nt_BP=159nt
AGTTGAGAGATGGCGGCCGCCGCAGGTAGATCGCTCCTGCTGCTCCTCTCCTCTCGGGGCGGCGGCGGCGGGGGCGCCGGCGGCTGCGGG
GCGCTGACTGCCGGCTGCTTCCCTGGGCTGGGCGTCAGCCGCCACCGGCAGCAGCAGCACCACCGGACGGATGAGTTCCACCCGTTCATC
GAGGCACTGCTGCCTCACGTCCGCGCTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAGAAGCATGAAAAG
CGGATGTCGAAGGACGAGGAGCGGGCGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCATCCCGGCTGCTG
GCCAAGCTGCGCAAGGACATCCGGCCCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGCTGCGTGCTCTCC
AACCCCGACCAGAAGGGCAAGATCCGGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTCATGGTGATTTTG
TTTAAGGGGATCCCCCTGGAAAGTACTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGCGTCCAGCCACAT
CACATTGGAGTCACAATCAAAGAACTGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGATAGTTCAAACCAG
CAAGGAGATGCGGACATCAAACCACTGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGGAATGTGACGGAG
CTGGTGAGAGTATCACAGACTCCTGTTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGCTACTACAACATC
AACCAGGTGACCCTGGGGCGGCGGTCCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGATGACAGTGAGATG
GAGAGCCCTGTTGATGACGTGTTCTATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGGCCCAACGATGTG
GATGCAGGCCCGGCTTCTCTAAAGAAGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCGCGCATGGCTTTC
ACCCACCACCCGCTGCCTGTGCTTGCTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCCTCCACGTCCATC
ATCCAGCAGTCGAGCCCGTATTTCACGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAGTTTGTGCAGTTT
GTGTGCTCGGATGGCTCGGGCCAGGCCACCGGACAGCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCAGCATCGGACCCC
GGGACGGCAACTTTCTGAACATCCCACAGCAGTCTCAGTCCTGGTTCCTCTGATAAGATCGACAAAAGAAACAACAAAATGAGAAGAAGA
GGTTCCTCGAAAGGGGGGAGAAGAAATTTTGAGAATGGAAAAATCCCCCAGCCCAGCCCAGCCCCACCGAAAAGCAAAAATTACACGTCG
TCAGCCACTCAGCCCTTCTCTCCTCCAGCCCGGGGACCCCCGCGGGCCCCAGAAGCAGCCCAGTTCTCAGAGAGCCCTTGGAAGGGGTCT
CGGTGGAGCTGTGCACCAGCAGCCAAGCAGAAAGAAACACGCGACATGGACTCTGTCAAGTAGAGGACAGAAAGCAAGAAAGGATGCAGA
ACTGCCTTCCTCCCCCTGACCCCGCCCCGGCCTTCTGGGGAAGGAACAAAGTCCCCAAACAAAGCAACCAGCACAATTCTGAAGGGGCCT
GGCCTCCACCCTCACCCCTTCCTAGGGGAACCCCACCCTCCACACAGCCGGAGCTGCCCTAGGGAGCCTGGAGGGCCAGCTTGTAAAGAT
GATGGGGTTTAGATCCCTCAGGCTCTCCCCTCCAGACTCCGCCCTTCCCTCCCTCCCTCCCTCCCTCCCTCTCTGCCAAGGCTCCAGCTT
CTTCCCCCAGCTGCTCCCGACCAGGAGGGGGAGAGCAGCCTCCACTTACCCCACCCCACCCTTGGGCTAAAAGCCCCCAGGCGGGCAGGG
GGTGACCCCTGGAGCTAGTTGCGTGTCCCAGAATGGAGGGTGTTCTGACACCCCACCCTGAGCCGCAAGAGCAGTCCTGGGGCCCTGGAC
CCCTCTGTACAGTCCGTAGGAAAAAGTCGGAATGCTCTCGACGGCCTCGTCCCAGCCTGGGACAGGCCCCCTTTCCCCTCTCTCTGCAGG
CCAGGAGGGCCTCCTTCCTGCCACGAGGGAGGGGAGTCGGGCCCCAGGTCGCCCCCGCCCCCAGCCCTGCATGCAGGTGCCCTCGCTCCG
CCCCATCAGTTCCTGCCCCTGCCCCTCATGCAGACTGCCCTGCTGGGGCCGGGCCGGAGGGTGGAGCAGAAAGGGGACCCCGGAGCCGAG
CGAGGAGGACCAGGCAGCCGCCGCTGCCGCGCTAAGCCACCACCTGCGCTTAGGTAGGCGTCCTGCTCGCCGACTTTCAGTTCCTTGGGA
GGGTGTTGGGTGTCGTCCTTTTCAAAAGTGTTTTGGAGCTTTCTGTGCCCCCCGACTTTCCCCCGCCTCCCCGCCCCCCACGTGGCCACT
TTTCTCTGGATTTTAGCTGTAATGTCTTTACTCTTTATTTAGGGGTGGGGCATTCATTGTTTGGGTCTTTTGCTGTTGGAATGGGAACTC
CTCCTCCATTTGAGCAACTTGGGAACAATTTGGTAACACACCACAGGAAGTAGCTCTCCCCCCCAGCCCCCTCCTCCCTCAAGGGAGGGT
TGGGGGGCCTGTCCAGAGGGTCTTCAGAAGCCCCCCTGGGAGGGAGGGGAGGATGAGCACGCCCAGCTCCCCTCCAGGGTGTGACTTGGC

>52326_52326_2_MCU-NFIX_MCU_chr10_74452059_ENST00000357157_NFIX_chr19_13135835_ENST00000397661_length(amino acids)=482AA_BP=15
MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMS
KDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKG
IPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVR
VSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAG
PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCS

--------------------------------------------------------------
>52326_52326_3_MCU-NFIX_MCU_chr10_74452059_ENST00000357157_NFIX_chr19_13135835_ENST00000585575_length(transcript)=1641nt_BP=159nt
AGTTGAGAGATGGCGGCCGCCGCAGGTAGATCGCTCCTGCTGCTCCTCTCCTCTCGGGGCGGCGGCGGCGGGGGCGCCGGCGGCTGCGGG
GCGCTGACTGCCGGCTGCTTCCCTGGGCTGGGCGTCAGCCGCCACCGGCAGCAGCAGCACCACCGGACGGATGAGTTCCACCCGTTCATC
GAGGCACTGCTGCCTCACGTCCGCGCTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAGAAGCATGAAAAG
CGGATGTCGAAGGACGAGGAGCGGGCGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCATCCCGGCTGCTG
GCCAAGCTGCGCAAGGACATCCGGCCCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGCTGCGTGCTCTCC
AACCCCGACCAGAAGGGCAAGATCCGGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTCATGGTGATTTTG
TTTAAGGGGATCCCCCTGGAAAGTACTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGCGTCCAGCCACAT
CACATTGGAGTCACAATCAAAGAACTGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGATAGTTCAAACCAG
CAAGGAGATGCGGACATCAAACCACTGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGGAATGTGACGGAG
CTGGTGAGAGTATCACAGACTCCTGTTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGCTACTACAACATC
AACCAGGTGACCCTGGGGCGGCGGTCCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGATGACAGTGAGATG
GAGAGCCCTGTTGATGACGTGTTCTATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGGCCCAACGATGTG
GATGCAGGCCCGGCTTCTCTAAAGAAGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCGCGCATGGCTTTC
ACCCACCACCCGCTGCCTGTGCTTGCTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCCTCCACGTCCATC
ATCCAGCAGTCGAGCCCGTATTTCACGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAGTTTGTGCAGTTT
GTGTGCTCGGATGGCTCGGGCCAGGCCACCGGACAGCCCAACGGTAGCGGCCAGGGCAAAGTCCCGGGGTCATTTTTGCTACCGCCGCCG
CCTCCAGTGGCCAGACCTGTGCCCCTTCCTATGCCTGATTCCAAATCCACCAGCACTGCCCCAGACGGCGCCGCCTTGACTCCTCCATCA
CCTTCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCAGCATCGGACCCCGGGACGGCAACTTTCTGAACATCCCACAGCAG

>52326_52326_3_MCU-NFIX_MCU_chr10_74452059_ENST00000357157_NFIX_chr19_13135835_ENST00000585575_length(amino acids)=543AA_BP=15
MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMS
KDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKG
IPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVR
VSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAG
PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCS
DGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPDGAALTPPSPSFATTGASSANRFVSIGPRDGNFLNIPQQSQS

--------------------------------------------------------------
>52326_52326_4_MCU-NFIX_MCU_chr10_74452059_ENST00000357157_NFIX_chr19_13135835_ENST00000587760_length(transcript)=1602nt_BP=159nt
AGTTGAGAGATGGCGGCCGCCGCAGGTAGATCGCTCCTGCTGCTCCTCTCCTCTCGGGGCGGCGGCGGCGGGGGCGCCGGCGGCTGCGGG
GCGCTGACTGCCGGCTGCTTCCCTGGGCTGGGCGTCAGCCGCCACCGGCAGCAGCAGCACCACCGGACGGATGAGTTCCACCCGTTCATC
GAGGCACTGCTGCCTCACGTCCGCGCTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAGAAGCATGAAAAG
CGGATGTCGAAGGACGAGGAGCGGGCGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCATCCCGGCTGCTG
GCCAAGCTGCGCAAGGACATCCGGCCCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGCTGCGTGCTCTCC
AACCCCGACCAGAAGGGCAAGATCCGGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTCATGGTGATTTTG
TTTAAGGGGATCCCCCTGGAAAGTACTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGCGTCCAGCCACAT
CACATTGGAGTCACAATCAAAGAACTGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGATAGTTCAAACCAG
CAAGGAGATGCGGACATCAAACCACTGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGGAATGTGACGGAG
CTGGTGAGAGTATCACAGACTCCTGTTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGCTACTACAACATC
AACCAGGTGACCCTGGGGCGGCGGTCCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGATGACAGTGAGATG
GAGAGCCCTGTTGATGACGTGTTCTATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGGCCCAACGATGTG
GATGCAGGCCCGGCTTCTCTAAAGAAGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCGCGCATGGCTTTC
ACCCACCACCCGCTGCCTGTGCTTGCTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCCTCCACGTCCATC
ATCCAGCAGTCGAGCCCGTATTTCACGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAGTTTGTGCAGTTT
GTGTGCTCGGATGGCTCGGGCCAGGCCACCGGACAGCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCAGCATCGGACCCC
GGGACGGCAACTTTCTGAACATCCCACAGCAGTCTCAGTCCTGGTTCCTCTGATAAGATCGACAAAAGAAACAACAAAATGAGAAGAAGA

>52326_52326_4_MCU-NFIX_MCU_chr10_74452059_ENST00000357157_NFIX_chr19_13135835_ENST00000587760_length(amino acids)=482AA_BP=15
MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMS
KDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKG
IPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVR
VSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAG
PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCS

--------------------------------------------------------------
>52326_52326_5_MCU-NFIX_MCU_chr10_74452059_ENST00000357157_NFIX_chr19_13135835_ENST00000592199_length(transcript)=1641nt_BP=159nt
AGTTGAGAGATGGCGGCCGCCGCAGGTAGATCGCTCCTGCTGCTCCTCTCCTCTCGGGGCGGCGGCGGCGGGGGCGCCGGCGGCTGCGGG
GCGCTGACTGCCGGCTGCTTCCCTGGGCTGGGCGTCAGCCGCCACCGGCAGCAGCAGCACCACCGGACGGATGAGTTCCACCCGTTCATC
GAGGCACTGCTGCCTCACGTCCGCGCTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAGAAGCATGAAAAG
CGGATGTCGAAGGACGAGGAGCGGGCGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCATCCCGGCTGCTG
GCCAAGCTGCGCAAGGACATCCGGCCCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGCTGCGTGCTCTCC
AACCCCGACCAGAAGGGCAAGATCCGGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTCATGGTGATTTTG
TTTAAGGGGATCCCCCTGGAAAGTACTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGCGTCCAGCCACAT
CACATTGGAGTCACAATCAAAGAACTGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGATAGTTCAAACCAG
CAAGGAGATGCGGACATCAAACCACTGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGGAATGTGACGGAG
CTGGTGAGAGTATCACAGACTCCTGTTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGCTACTACAACATC
AACCAGGTGACCCTGGGGCGGCGGTCCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGATGACAGTGAGATG
GAGAGCCCTGTTGATGACGTGTTCTATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGGCCCAACGATGTG
GATGCAGGCCCGGCTTCTCTAAAGAAGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCGCGCATGGCTTTC
ACCCACCACCCGCTGCCTGTGCTTGCTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCCTCCACGTCCATC
ATCCAGCAGTCGAGCCCGTATTTCACGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAGTTTGTGCAGTTT
GTGTGCTCGGATGGCTCGGGCCAGGCCACCGGACAGCCCAACGGTAGCGGCCAGGGCAAAGTCCCGGGGTCATTTTTGCTACCGCCGCCG
CCTCCAGTGGCCAGACCTGTGCCCCTTCCTATGCCTGATTCCAAATCCACCAGCACTGCCCCAGACGGCGCCGCCTTGACTCCTCCATCA
CCTTCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCAGCATCGGACCCCGGGACGGCAACTTTCTGAACATCCCACAGCAG

>52326_52326_5_MCU-NFIX_MCU_chr10_74452059_ENST00000357157_NFIX_chr19_13135835_ENST00000592199_length(amino acids)=543AA_BP=15
MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMS
KDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKG
IPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVR
VSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAG
PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCS
DGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPDGAALTPPSPSFATTGASSANRFVSIGPRDGNFLNIPQQSQS

--------------------------------------------------------------
>52326_52326_6_MCU-NFIX_MCU_chr10_74452059_ENST00000373053_NFIX_chr19_13135835_ENST00000360105_length(transcript)=5529nt_BP=171nt
GGCGCCGTTTCCAGTTGAGAGATGGCGGCCGCCGCAGGTAGATCGCTCCTGCTGCTCCTCTCCTCTCGGGGCGGCGGCGGCGGGGGCGCC
GGCGGCTGCGGGGCGCTGACTGCCGGCTGCTTCCCTGGGCTGGGCGTCAGCCGCCACCGGCAGCAGCAGCACCACCGGACGGATGAGTTC
CACCCGTTCATCGAGGCACTGCTGCCTCACGTCCGCGCTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAG
AAGCATGAAAAGCGGATGTCGAAGGACGAGGAGCGGGCGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCA
TCCCGGCTGCTGGCCAAGCTGCGCAAGGACATCCGGCCCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGC
TGCGTGCTCTCCAACCCCGACCAGAAGGGCAAGATCCGGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTC
ATGGTGATTTTGTTTAAGGGGATCCCCCTGGAAAGTACTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGC
GTCCAGCCACATCACATTGGAGTCACAATCAAAGAACTGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGAT
AGTTCAAACCAGCAAGGAGATGCGGACATCAAACCACTGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGG
AATGTGACGGAGCTGGTGAGAGTATCACAGACTCCTGTTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGC
TACTACAACATCAACCAGGTGACCCTGGGGCGGCGGTCCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGAT
GACAGTGAGATGGAGAGCCCTGTTGATGACGTGTTCTATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGG
CCCAACGATGTGGATGCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCCTCCACGTCCATCATCCAGCAGTCGAGCCCGTAT
TTCACGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAGTTTGTGCAGTTTGTGTGCTCGGATGGCTCGGGC
CAGGCCACCGGACAGCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCAGCATCGGACCCCGGGACGGCAACTTTCTGAACA
TCCCACAGCAGTCTCAGTCCTGGTTCCTCTGATAAGATCGACAAAAGAAACAACAAAATGAGAAGAAGAGGTTCCTCGAAAGGGGGGAGA
AGAAATTTTGAGAATGGAAAAATCCCCCAGCCCAGCCCAGCCCCACCGAAAAGCAAAAATTACACGTCGTCAGCCACTCAGCCCTTCTCT
CCTCCAGCCCGGGGACCCCCGCGGGCCCCAGAAGCAGCCCAGTTCTCAGAGAGCCCTTGGAAGGGGTCTCGGTGGAGCTGTGCACCAGCA
GCCAAGCAGAAAGAAACACGCGACATGGACTCTGTCAAGTAGAGGACAGAAAGCAAGAAAGGATGCAGAACTGCCTTCCTCCCCCTGACC
CCGCCCCGGCCTTCTGGGGAAGGAACAAAGTCCCCAAACAAAGCAACCAGCACAATTCTGAAGGGGCCTGGCCTCCACCCTCACCCCTTC
CTAGGGGAACCCCACCCTCCACACAGCCGGAGCTGCCCTAGGGAGCCTGGAGGGCCAGCTTGTAAAGATGATGGGGTTTAGATCCCTCAG
GCTCTCCCCTCCAGACTCCGCCCTTCCCTCCCTCCCTCCCTCCCTCCCTCTCTGCCAAGGCTCCAGCTTCTTCCCCCAGCTGCTCCCGAC
CAGGAGGGGGAGAGCAGCCTCCACTTACCCCACCCCACCCTTGGGCTAAAAGCCCCCAGGCGGGCAGGGGGTGACCCCTGGAGCTAGTTG
CGTGTCCCAGAATGGAGGGTGTTCTGACACCCCACCCTGAGCCGCAAGAGCAGTCCTGGGGCCCTGGACCCCTCTGTACAGTCCGTAGGA
AAAAGTCGGAATGCTCTCGACGGCCTCGTCCCAGCCTGGGACAGGCCCCCTTTCCCCTCTCTCTGCAGGCCAGGAGGGCCTCCTTCCTGC
CACGAGGGAGGGGAGTCGGGCCCCAGGTCGCCCCCGCCCCCAGCCCTGCATGCAGGTGCCCTCGCTCCGCCCCATCAGTTCCTGCCCCTG
CCCCTCATGCAGACTGCCCTGCTGGGGCCGGGCCGGAGGGTGGAGCAGAAAGGGGACCCCGGAGCCGAGCGAGGAGGACCAGGCAGCCGC
CGCTGCCGCGCTAAGCCACCACCTGCGCTTAGGTAGGCGTCCTGCTCGCCGACTTTCAGTTCCTTGGGAGGGTGTTGGGTGTCGTCCTTT
TCAAAAGTGTTTTGGAGCTTTCTGTGCCCCCCGACTTTCCCCCGCCTCCCCGCCCCCCACGTGGCCACTTTTCTCTGGATTTTAGCTGTA
ATGTCTTTACTCTTTATTTAGGGGTGGGGCATTCATTGTTTGGGTCTTTTGCTGTTGGAATGGGAACTCCTCCTCCATTTGAGCAACTTG
GGAACAATTTGGTAACACACCACAGGAAGTAGCTCTCCCCCCCAGCCCCCTCCTCCCTCAAGGGAGGGTTGGGGGGCCTGTCCAGAGGGT
CTTCAGAAGCCCCCCTGGGAGGGAGGGGAGGATGAGCACGCCCAGCTCCCCTCCAGGGTGTGACTTGGCCCCTCTGGCTTGTCTTTCTGT
GCCTTACTCCTCCTCCTGCGTCTCCCGTTCCTGGCCCCTTCTTGAGTCCTTGTGCCTCTCTCTTTCTCTCTCTTTCTTAATTGTATGAAA
ACACAAAGCACAGGTCAGGATCCTCTGAGAGAAAATCAACATTGCACCACGTAGGGGTGGGCTATGGGCTGTATTTATTGTGAATCTAGT
TTGTGAGGCTGTGGCCCCGAGCTGGCGGAGGGAGGGAAGAGGAGGGAGTGACGGGAGGGGAGGAGGTCAGCGACCTGGGGCCGTAGCGGC
AGGCGAACGGTGCCTGCTACCCAGCTGGAAGCCACAAGGTGGCTGGCTCCAGGGGCGGCTTTTGTTGGAAGTTGAGTGAAGCCCTCCCCC
TGTCCTCAGCGTGCAGCCCTAGAGGACCCCAGGGCTGAGGGGCAGTGGATCCTGCGGGAGTCTCCCGGGGCGTGGGGAGTAAGGCCCCGG
GGGTGGGGGGCCGGGTGGGCCGGGCGTGACGCGCGGTCAAAGTGCAATGATTTTTCAGTTCGGTTGGCTAAACAGGGTCAGAGCTGAGAG
CGAAGCAGAAGGGGCTCCCTGTCCGGCCCACGTGCCCTTTCCCTCGACGACAGTCGAGGGCTCGGGCTCTGTGGGACTGTGGGAGCTAGG
GTCTGCGGGGCGCCTGCCCGGGCGAGGTCGGAAGCTGCAGGCCAGCTGGGCCCGGGCCGGAGCGTGCCCGGCGGGGCTGCCCGGGCGGGC
AGGGGGTGGGGGCTGCTCCTTTCCCAAGTGGTGTTGTGAGGGGCAATGAGGGCAACAGGAGATGTGGGGACGTGTTAGGAGAGAAAAAAA
AAAAAACAAAAATATATATGGGGGAAATTAACTTTTTTTTTTCATTGAACCAAGTGCAATGCATCAGAGAGTTTTCCTATCTTTGTATGT
TAAGAGATTAAGAAAAAAAAATTCTATTTTTGTTGTAATGTCCTCGCGGCTCTGGGGACGCTAAAAGAACCGGGCCTGCCCCGCCCTGCG
CGGGGATAACGAAAGCTGAGTGTTTTTCCCTTTTTTTTGTTCGTTTTTAGTTTTTTTTTTTTTAAGTCGTTTTCCTGCGTTGACGAGGAT
GATCTGGGGTTTTTATTTGTTTCGTCGTTCGTTCTGTTTCGGTGGGAGGGCTGAAGGAAACGTTCACATTTTAGAGTTTAAAAAAAACAC
CTCGACATTTAAAAAATCAACCAACACAAGATCAAAAAGGAAAAGGACGAGAGAAAAATTATTTTTAAGATAATTAAACATAAAACCCTG
GTGCTTCTTACATTATAAAGTACGTTTTAAAGAACCCACAAACTATTATACATAAGTTTATGAATCAATTAAATATCCTGCACTTGTTAG
GAATACGCATATCCCTTCTTTGTTGAGTTTAACGGAACGGGACAGCGGCGTGCCCCCGGCGGCTGGACTGCTCCGGCCGCGGGTCTCCCC
GGGCGCCCCTCCCTGGGGCCCAGCACCCCTCCTCGCCCCATCCCCGTCCGGGTACGGGGGCGCGGCAGGGGTCCCCGGCCCCTCCCCCGC
AGAGGTCAATGCCAACGAACAAACGTCCCCTCCCTCCCTCCCTCTCCGCCCCGAGCGCCCTTCTTTGAGCCAGACGCCAACTTGACCCTC
ACCAGCATTATCAGGAGCGCGCTCAGCAAGTTGGTAGTTTCCTCCCCCCTTTCCCGGCGCCCCTCCCGCCCCCATTCAACATCTCTCATC
CTATCCCCGACCCCCTCCGGGGAACACCGGGAAGGCTCGACGCTCCAGGACAGGACCAGCCACGCAGACAGGTCGATTTGCCCAGGCCCG
CGCCCGCACGCACGCACGCACACGGCCCCGCACACAGCCCCGCCCCACCCCGCAACCAGCCCTGTCGACTGCCTTATACACCCGCCCCCG
CGCTGGCCGGCCGACCTAGTGCCTTGTTCTCACCCCCGTGCTGGCGGAGCGGACGCCGCGCTCTGGGTCCCAGAGGGGCCGGGTGGCTCA
GACGACCCACCACTCCCCCACCCTGACCGTGCTGAACAGACCCCCCCACACGAGAGAAAATAAAGGAGCAATAAAGTCACGAGAACTTTC
GTCCCCCAATCGAGAGCCCGAGGGGCACCCCAGCCCCGCCTCTGCTCCCCCCCACCCCACCCACCCTCGGGGCGCCCCCCTCCCCCCGCA
AGCCAGCCTGGGCCAGCCCCGCTTCGGCCCCTCCCGGGAGATCCGTGCGCCCGACCAGCACCAGCATCGCGGACCGCAAAGGCCGCCCGT
CCCGTCAAACAAGTTTCTTCTTAGGCTAAGAAACGCAGTATATACGAGTATCTCTATATATAGTACTAATGGATTTGGTGTGCTTCCCCC
TTAGCGTCCCCCTCCCTCTGCTCCTCCTCCTTCAGCCTGGTCTCCCCCTCTTCTCTGCCCTCCACCCCCGTCTCTGCACTGAGATACATA
AGAAACAAGGGTAGTTTACTGTCTGTTTTGTTTTCTGGGTTTTCAGTGTCCTAGCGGAATGCAAGTAGGCAGCCAGCCCGTCTGTTCCCT
CTCCGCCCCGCCCCGCCCCGCCCCCGTCACTGCGCTTCTGTTATACCATCTTTGCCTGACTCTCTCCGGCTTCTCCATTGAATGGCTAAT

>52326_52326_6_MCU-NFIX_MCU_chr10_74452059_ENST00000373053_NFIX_chr19_13135835_ENST00000360105_length(amino acids)=441AA_BP=15
MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMS
KDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKG
IPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVR
VSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAG

--------------------------------------------------------------
>52326_52326_7_MCU-NFIX_MCU_chr10_74452059_ENST00000373053_NFIX_chr19_13135835_ENST00000397661_length(transcript)=3057nt_BP=171nt
GGCGCCGTTTCCAGTTGAGAGATGGCGGCCGCCGCAGGTAGATCGCTCCTGCTGCTCCTCTCCTCTCGGGGCGGCGGCGGCGGGGGCGCC
GGCGGCTGCGGGGCGCTGACTGCCGGCTGCTTCCCTGGGCTGGGCGTCAGCCGCCACCGGCAGCAGCAGCACCACCGGACGGATGAGTTC
CACCCGTTCATCGAGGCACTGCTGCCTCACGTCCGCGCTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAG
AAGCATGAAAAGCGGATGTCGAAGGACGAGGAGCGGGCGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCA
TCCCGGCTGCTGGCCAAGCTGCGCAAGGACATCCGGCCCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGC
TGCGTGCTCTCCAACCCCGACCAGAAGGGCAAGATCCGGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTC
ATGGTGATTTTGTTTAAGGGGATCCCCCTGGAAAGTACTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGC
GTCCAGCCACATCACATTGGAGTCACAATCAAAGAACTGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGAT
AGTTCAAACCAGCAAGGAGATGCGGACATCAAACCACTGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGG
AATGTGACGGAGCTGGTGAGAGTATCACAGACTCCTGTTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGC
TACTACAACATCAACCAGGTGACCCTGGGGCGGCGGTCCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGAT
GACAGTGAGATGGAGAGCCCTGTTGATGACGTGTTCTATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGG
CCCAACGATGTGGATGCAGGCCCGGCTTCTCTAAAGAAGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCG
CGCATGGCTTTCACCCACCACCCGCTGCCTGTGCTTGCTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCC
TCCACGTCCATCATCCAGCAGTCGAGCCCGTATTTCACGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAG
TTTGTGCAGTTTGTGTGCTCGGATGGCTCGGGCCAGGCCACCGGACAGCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCA
GCATCGGACCCCGGGACGGCAACTTTCTGAACATCCCACAGCAGTCTCAGTCCTGGTTCCTCTGATAAGATCGACAAAAGAAACAACAAA
ATGAGAAGAAGAGGTTCCTCGAAAGGGGGGAGAAGAAATTTTGAGAATGGAAAAATCCCCCAGCCCAGCCCAGCCCCACCGAAAAGCAAA
AATTACACGTCGTCAGCCACTCAGCCCTTCTCTCCTCCAGCCCGGGGACCCCCGCGGGCCCCAGAAGCAGCCCAGTTCTCAGAGAGCCCT
TGGAAGGGGTCTCGGTGGAGCTGTGCACCAGCAGCCAAGCAGAAAGAAACACGCGACATGGACTCTGTCAAGTAGAGGACAGAAAGCAAG
AAAGGATGCAGAACTGCCTTCCTCCCCCTGACCCCGCCCCGGCCTTCTGGGGAAGGAACAAAGTCCCCAAACAAAGCAACCAGCACAATT
CTGAAGGGGCCTGGCCTCCACCCTCACCCCTTCCTAGGGGAACCCCACCCTCCACACAGCCGGAGCTGCCCTAGGGAGCCTGGAGGGCCA
GCTTGTAAAGATGATGGGGTTTAGATCCCTCAGGCTCTCCCCTCCAGACTCCGCCCTTCCCTCCCTCCCTCCCTCCCTCCCTCTCTGCCA
AGGCTCCAGCTTCTTCCCCCAGCTGCTCCCGACCAGGAGGGGGAGAGCAGCCTCCACTTACCCCACCCCACCCTTGGGCTAAAAGCCCCC
AGGCGGGCAGGGGGTGACCCCTGGAGCTAGTTGCGTGTCCCAGAATGGAGGGTGTTCTGACACCCCACCCTGAGCCGCAAGAGCAGTCCT
GGGGCCCTGGACCCCTCTGTACAGTCCGTAGGAAAAAGTCGGAATGCTCTCGACGGCCTCGTCCCAGCCTGGGACAGGCCCCCTTTCCCC
TCTCTCTGCAGGCCAGGAGGGCCTCCTTCCTGCCACGAGGGAGGGGAGTCGGGCCCCAGGTCGCCCCCGCCCCCAGCCCTGCATGCAGGT
GCCCTCGCTCCGCCCCATCAGTTCCTGCCCCTGCCCCTCATGCAGACTGCCCTGCTGGGGCCGGGCCGGAGGGTGGAGCAGAAAGGGGAC
CCCGGAGCCGAGCGAGGAGGACCAGGCAGCCGCCGCTGCCGCGCTAAGCCACCACCTGCGCTTAGGTAGGCGTCCTGCTCGCCGACTTTC
AGTTCCTTGGGAGGGTGTTGGGTGTCGTCCTTTTCAAAAGTGTTTTGGAGCTTTCTGTGCCCCCCGACTTTCCCCCGCCTCCCCGCCCCC
CACGTGGCCACTTTTCTCTGGATTTTAGCTGTAATGTCTTTACTCTTTATTTAGGGGTGGGGCATTCATTGTTTGGGTCTTTTGCTGTTG
GAATGGGAACTCCTCCTCCATTTGAGCAACTTGGGAACAATTTGGTAACACACCACAGGAAGTAGCTCTCCCCCCCAGCCCCCTCCTCCC
TCAAGGGAGGGTTGGGGGGCCTGTCCAGAGGGTCTTCAGAAGCCCCCCTGGGAGGGAGGGGAGGATGAGCACGCCCAGCTCCCCTCCAGG

>52326_52326_7_MCU-NFIX_MCU_chr10_74452059_ENST00000373053_NFIX_chr19_13135835_ENST00000397661_length(amino acids)=482AA_BP=15
MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMS
KDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKG
IPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVR
VSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAG
PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCS

--------------------------------------------------------------
>52326_52326_8_MCU-NFIX_MCU_chr10_74452059_ENST00000373053_NFIX_chr19_13135835_ENST00000585575_length(transcript)=1653nt_BP=171nt
GGCGCCGTTTCCAGTTGAGAGATGGCGGCCGCCGCAGGTAGATCGCTCCTGCTGCTCCTCTCCTCTCGGGGCGGCGGCGGCGGGGGCGCC
GGCGGCTGCGGGGCGCTGACTGCCGGCTGCTTCCCTGGGCTGGGCGTCAGCCGCCACCGGCAGCAGCAGCACCACCGGACGGATGAGTTC
CACCCGTTCATCGAGGCACTGCTGCCTCACGTCCGCGCTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAG
AAGCATGAAAAGCGGATGTCGAAGGACGAGGAGCGGGCGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCA
TCCCGGCTGCTGGCCAAGCTGCGCAAGGACATCCGGCCCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGC
TGCGTGCTCTCCAACCCCGACCAGAAGGGCAAGATCCGGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTC
ATGGTGATTTTGTTTAAGGGGATCCCCCTGGAAAGTACTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGC
GTCCAGCCACATCACATTGGAGTCACAATCAAAGAACTGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGAT
AGTTCAAACCAGCAAGGAGATGCGGACATCAAACCACTGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGG
AATGTGACGGAGCTGGTGAGAGTATCACAGACTCCTGTTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGC
TACTACAACATCAACCAGGTGACCCTGGGGCGGCGGTCCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGAT
GACAGTGAGATGGAGAGCCCTGTTGATGACGTGTTCTATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGG
CCCAACGATGTGGATGCAGGCCCGGCTTCTCTAAAGAAGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCG
CGCATGGCTTTCACCCACCACCCGCTGCCTGTGCTTGCTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCC
TCCACGTCCATCATCCAGCAGTCGAGCCCGTATTTCACGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAG
TTTGTGCAGTTTGTGTGCTCGGATGGCTCGGGCCAGGCCACCGGACAGCCCAACGGTAGCGGCCAGGGCAAAGTCCCGGGGTCATTTTTG
CTACCGCCGCCGCCTCCAGTGGCCAGACCTGTGCCCCTTCCTATGCCTGATTCCAAATCCACCAGCACTGCCCCAGACGGCGCCGCCTTG
ACTCCTCCATCACCTTCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCAGCATCGGACCCCGGGACGGCAACTTTCTGAAC

>52326_52326_8_MCU-NFIX_MCU_chr10_74452059_ENST00000373053_NFIX_chr19_13135835_ENST00000585575_length(amino acids)=543AA_BP=15
MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMS
KDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKG
IPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVR
VSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAG
PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCS
DGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPDGAALTPPSPSFATTGASSANRFVSIGPRDGNFLNIPQQSQS

--------------------------------------------------------------
>52326_52326_9_MCU-NFIX_MCU_chr10_74452059_ENST00000373053_NFIX_chr19_13135835_ENST00000587760_length(transcript)=1614nt_BP=171nt
GGCGCCGTTTCCAGTTGAGAGATGGCGGCCGCCGCAGGTAGATCGCTCCTGCTGCTCCTCTCCTCTCGGGGCGGCGGCGGCGGGGGCGCC
GGCGGCTGCGGGGCGCTGACTGCCGGCTGCTTCCCTGGGCTGGGCGTCAGCCGCCACCGGCAGCAGCAGCACCACCGGACGGATGAGTTC
CACCCGTTCATCGAGGCACTGCTGCCTCACGTCCGCGCTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAG
AAGCATGAAAAGCGGATGTCGAAGGACGAGGAGCGGGCGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCA
TCCCGGCTGCTGGCCAAGCTGCGCAAGGACATCCGGCCCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGC
TGCGTGCTCTCCAACCCCGACCAGAAGGGCAAGATCCGGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTC
ATGGTGATTTTGTTTAAGGGGATCCCCCTGGAAAGTACTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGC
GTCCAGCCACATCACATTGGAGTCACAATCAAAGAACTGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGAT
AGTTCAAACCAGCAAGGAGATGCGGACATCAAACCACTGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGG
AATGTGACGGAGCTGGTGAGAGTATCACAGACTCCTGTTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGC
TACTACAACATCAACCAGGTGACCCTGGGGCGGCGGTCCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGAT
GACAGTGAGATGGAGAGCCCTGTTGATGACGTGTTCTATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGG
CCCAACGATGTGGATGCAGGCCCGGCTTCTCTAAAGAAGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCG
CGCATGGCTTTCACCCACCACCCGCTGCCTGTGCTTGCTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCC
TCCACGTCCATCATCCAGCAGTCGAGCCCGTATTTCACGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAG
TTTGTGCAGTTTGTGTGCTCGGATGGCTCGGGCCAGGCCACCGGACAGCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCA
GCATCGGACCCCGGGACGGCAACTTTCTGAACATCCCACAGCAGTCTCAGTCCTGGTTCCTCTGATAAGATCGACAAAAGAAACAACAAA

>52326_52326_9_MCU-NFIX_MCU_chr10_74452059_ENST00000373053_NFIX_chr19_13135835_ENST00000587760_length(amino acids)=482AA_BP=15
MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMS
KDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKG
IPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVR
VSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAG
PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCS

--------------------------------------------------------------
>52326_52326_10_MCU-NFIX_MCU_chr10_74452059_ENST00000373053_NFIX_chr19_13135835_ENST00000592199_length(transcript)=1653nt_BP=171nt
GGCGCCGTTTCCAGTTGAGAGATGGCGGCCGCCGCAGGTAGATCGCTCCTGCTGCTCCTCTCCTCTCGGGGCGGCGGCGGCGGGGGCGCC
GGCGGCTGCGGGGCGCTGACTGCCGGCTGCTTCCCTGGGCTGGGCGTCAGCCGCCACCGGCAGCAGCAGCACCACCGGACGGATGAGTTC
CACCCGTTCATCGAGGCACTGCTGCCTCACGTCCGCGCTTTCTCCTACACCTGGTTCAACCTGCAGGCGCGGAAGCGCAAGTACTTCAAG
AAGCATGAAAAGCGGATGTCGAAGGACGAGGAGCGGGCGGTGAAGGACGAGCTGCTGGGCGAGAAGCCCGAGATCAAGCAGAAGTGGGCA
TCCCGGCTGCTGGCCAAGCTGCGCAAGGACATCCGGCCCGAGTTCCGCGAGGACTTCGTGCTGACCATCACGGGCAAGAAGCCCCCCTGC
TGCGTGCTCTCCAACCCCGACCAGAAGGGCAAGATCCGGCGGATTGACTGCCTGCGCCAGGCTGACAAGGTGTGGCGGCTGGACCTGGTC
ATGGTGATTTTGTTTAAGGGGATCCCCCTGGAAAGTACTGATGGGGAGCGGCTCTACAAGTCGCCTCAGTGCTCGAACCCCGGCCTGTGC
GTCCAGCCACATCACATTGGAGTCACAATCAAAGAACTGGATCTTTATCTGGCTTACTTTGTCCACACTCCGGAATCCGGACAATCAGAT
AGTTCAAACCAGCAAGGAGATGCGGACATCAAACCACTGCCCAACGGGCACTTAAGTTTCCAGGACTGTTTTGTGACTTCCGGGGTCTGG
AATGTGACGGAGCTGGTGAGAGTATCACAGACTCCTGTTGCAACAGCATCAGGGCCCAACTTCTCCCTGGCGGACCTGGAGAGTCCCAGC
TACTACAACATCAACCAGGTGACCCTGGGGCGGCGGTCCATCACCTCCCCTCCTTCCACCAGCACCACCAAGCGCCCCAAGTCCATCGAT
GACAGTGAGATGGAGAGCCCTGTTGATGACGTGTTCTATCCCGGGACAGGCCGTTCCCCAGCAGCTGGCAGCAGCCAGTCCAGCGGGTGG
CCCAACGATGTGGATGCAGGCCCGGCTTCTCTAAAGAAGTCAGGAAAGCTGGACTTCTGCAGTGCCCTCTCCTCTCAGGGCAGCTCCCCG
CGCATGGCTTTCACCCACCACCCGCTGCCTGTGCTTGCTGGAGTCAGACCAGGGAGCCCCCGGGCCACAGCATCAGCCCTGCACTTCCCC
TCCACGTCCATCATCCAGCAGTCGAGCCCGTATTTCACGCACCCGACCATCCGCTACCACCACCACCACGGGCAGGACTCACTGAAGGAG
TTTGTGCAGTTTGTGTGCTCGGATGGCTCGGGCCAGGCCACCGGACAGCCCAACGGTAGCGGCCAGGGCAAAGTCCCGGGGTCATTTTTG
CTACCGCCGCCGCCTCCAGTGGCCAGACCTGTGCCCCTTCCTATGCCTGATTCCAAATCCACCAGCACTGCCCCAGACGGCGCCGCCTTG
ACTCCTCCATCACCTTCATTCGCAACGACAGGCGCCTCCTCTGCCAACCGGTTTGTCAGCATCGGACCCCGGGACGGCAACTTTCTGAAC

>52326_52326_10_MCU-NFIX_MCU_chr10_74452059_ENST00000373053_NFIX_chr19_13135835_ENST00000592199_length(amino acids)=543AA_BP=15
MAAAAGRSLLLLLSSRGGGGGGAGGCGALTAGCFPGLGVSRHRQQQHHRTDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMS
KDEERAVKDELLGEKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRLDLVMVILFKG
IPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESGQSDSSNQQGDADIKPLPNGHLSFQDCFVTSGVWNVTELVR
VSQTPVATASGPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGSSQSSGWPNDVDAG
PASLKKSGKLDFCSALSSQGSSPRMAFTHHPLPVLAGVRPGSPRATASALHFPSTSIIQQSSPYFTHPTIRYHHHHGQDSLKEFVQFVCS
DGSGQATGQPNGSGQGKVPGSFLLPPPPPVARPVPLPMPDSKSTSTAPDGAALTPPSPSFATTGASSANRFVSIGPRDGNFLNIPQQSQS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MCU-NFIX


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MCU-NFIX


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MCU-NFIX


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource