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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MDM2-XPOT (FusionGDB2 ID:52427)

Fusion Gene Summary for MDM2-XPOT

check button Fusion gene summary
Fusion gene informationFusion gene name: MDM2-XPOT
Fusion gene ID: 52427
HgeneTgene
Gene symbol

MDM2

XPOT

Gene ID

4193

11260

Gene nameMDM2 proto-oncogeneexportin for tRNA
SynonymsACTFS|HDMX|LSKB|hdm2XPO3
Cytomap

12q15

12q14.2

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase Mdm2MDM2 oncogene, E3 ubiquitin protein ligaseMDM2 proto-oncogene, E3 ubiquitin protein ligaseMdm2, p53 E3 ubiquitin protein ligase homologMdm2, transformed 3T3 cell double minute 2, p53 binding proteindouble minute 2, humexportin-Texportin(tRNA)exportin, tRNA (nuclear export receptor for tRNAs)tRNA exportin
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000258148, ENST00000258149, 
ENST00000350057, ENST00000462284, 
ENST00000299252, ENST00000348801, 
ENST00000356290, ENST00000360430, 
ENST00000393410, ENST00000393412, 
ENST00000393413, ENST00000428863, 
ENST00000478070, ENST00000517852, 
ENST00000540827, ENST00000544125, 
ENST00000544561, ENST00000545204, 
ENST00000332707, 
Fusion gene scores* DoF score39 X 20 X 11=858010 X 11 X 6=660
# samples 4712
** MAII scorelog2(47/8580*10)=-4.19024498582191
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/660*10)=-2.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MDM2 [Title/Abstract] AND XPOT [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMDM2(69222710)-XPOT(64833023), # samples:1
MDM2(69222711)-XPOT(64833023), # samples:1
MDM2(69222711)-XPOT(64833024), # samples:1
MDM2(69222711)-XPOT(64838855), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMDM2

GO:0000122

negative regulation of transcription by RNA polymerase II

9271120|17310983

HgeneMDM2

GO:0006511

ubiquitin-dependent protein catabolic process

11278372|15314173|16173922|17310983

HgeneMDM2

GO:0016567

protein ubiquitination

9450543|15878855|19656744|20153724

HgeneMDM2

GO:0031648

protein destabilization

9529249|10360174|15314173

HgeneMDM2

GO:0032436

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

11278372

HgeneMDM2

GO:0034504

protein localization to nucleus

10360174

HgeneMDM2

GO:0042176

regulation of protein catabolic process

9153395

HgeneMDM2

GO:0043518

negative regulation of DNA damage response, signal transduction by p53 class mediator

9529249|10360174

HgeneMDM2

GO:0045184

establishment of protein localization

10360174

HgeneMDM2

GO:0045892

negative regulation of transcription, DNA-templated

9271120

HgeneMDM2

GO:0065003

protein-containing complex assembly

10608892|12915590

HgeneMDM2

GO:0071157

negative regulation of cell cycle arrest

9529249

HgeneMDM2

GO:0071480

cellular response to gamma radiation

16213212

HgeneMDM2

GO:0072717

cellular response to actinomycin D

15314173

HgeneMDM2

GO:1901797

negative regulation of signal transduction by p53 class mediator

16173922

TgeneXPOT

GO:0006409

tRNA export from nucleus

9660920


check buttonFusion gene breakpoints across MDM2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across XPOT (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AN-A0AM-01AMDM2chr12

69222710

+XPOTchr12

64833023

+
ChimerDB4BRCATCGA-AN-A0AM-01AMDM2chr12

69222711

+XPOTchr12

64833024

+
ChimerDB4BRCATCGA-AN-A0AM-01AMDM2chr12

69222711

+XPOTchr12

64838855

+
ChimerDB4BRCATCGA-AN-A0AMMDM2chr12

69222711

+XPOTchr12

64833023

+


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Fusion Gene ORF analysis for MDM2-XPOT

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000258148ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
In-frameENST00000258148ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
In-frameENST00000258148ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
In-frameENST00000258148ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
In-frameENST00000258149ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
In-frameENST00000258149ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
In-frameENST00000258149ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
In-frameENST00000258149ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
In-frameENST00000350057ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
In-frameENST00000350057ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
In-frameENST00000350057ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
In-frameENST00000350057ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
In-frameENST00000462284ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
In-frameENST00000462284ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
In-frameENST00000462284ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
In-frameENST00000462284ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000299252ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000299252ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000299252ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000299252ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000348801ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000348801ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000348801ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000348801ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000356290ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000356290ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000356290ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000356290ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000360430ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000360430ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000360430ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000360430ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000393410ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000393410ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000393410ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000393410ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000393412ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000393412ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000393412ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000393412ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000393413ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000393413ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000393413ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000393413ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000428863ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000428863ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000428863ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000428863ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000478070ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000478070ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000478070ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000478070ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000517852ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000517852ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000517852ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000517852ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000540827ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000540827ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000540827ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000540827ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000544125ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000544125ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000544125ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000544125ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000544561ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000544561ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000544561ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000544561ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+
intron-3CDSENST00000545204ENST00000332707MDM2chr12

69222710

+XPOTchr12

64833023

+
intron-3CDSENST00000545204ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833024

+
intron-3CDSENST00000545204ENST00000332707MDM2chr12

69222711

+XPOTchr12

64838855

+
intron-3CDSENST00000545204ENST00000332707MDM2chr12

69222711

+XPOTchr12

64833023

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000462284MDM2chr1269222710+ENST00000332707XPOTchr1264833023+41389862661141291
ENST00000258149MDM2chr1269222710+ENST00000332707XPOTchr1264833023+3958806251961236
ENST00000258148MDM2chr1269222710+ENST00000332707XPOTchr1264833023+368553314688224
ENST00000350057MDM2chr1269222710+ENST00000332707XPOTchr1264833023+37435910746248
ENST00000462284MDM2chr1269222711+ENST00000332707XPOTchr1264833023+41389862661141291
ENST00000258149MDM2chr1269222711+ENST00000332707XPOTchr1264833023+3958806251961236
ENST00000258148MDM2chr1269222711+ENST00000332707XPOTchr1264833023+368553314688224
ENST00000350057MDM2chr1269222711+ENST00000332707XPOTchr1264833023+37435910746248
ENST00000462284MDM2chr1269222711+ENST00000332707XPOTchr1264833024+41389862661141291
ENST00000258149MDM2chr1269222711+ENST00000332707XPOTchr1264833024+3958806251961236
ENST00000258148MDM2chr1269222711+ENST00000332707XPOTchr1264833024+368553314688224
ENST00000350057MDM2chr1269222711+ENST00000332707XPOTchr1264833024+37435910746248
ENST00000462284MDM2chr1269222711+ENST00000332707XPOTchr1264838855+40669862661069267
ENST00000258149MDM2chr1269222711+ENST00000332707XPOTchr1264838855+3886806251889212
ENST00000258148MDM2chr1269222711+ENST00000332707XPOTchr1264838855+361353314616200
ENST00000350057MDM2chr1269222711+ENST00000332707XPOTchr1264838855+36715910674224

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000462284ENST00000332707MDM2chr1269222710+XPOTchr1264833023+0.0006698070.99933016
ENST00000258149ENST00000332707MDM2chr1269222710+XPOTchr1264833023+0.0013103360.9986897
ENST00000258148ENST00000332707MDM2chr1269222710+XPOTchr1264833023+0.0010465070.99895346
ENST00000350057ENST00000332707MDM2chr1269222710+XPOTchr1264833023+0.0013161930.99868375
ENST00000462284ENST00000332707MDM2chr1269222711+XPOTchr1264833023+0.0006698070.99933016
ENST00000258149ENST00000332707MDM2chr1269222711+XPOTchr1264833023+0.0013103360.9986897
ENST00000258148ENST00000332707MDM2chr1269222711+XPOTchr1264833023+0.0010465070.99895346
ENST00000350057ENST00000332707MDM2chr1269222711+XPOTchr1264833023+0.0013161930.99868375
ENST00000462284ENST00000332707MDM2chr1269222711+XPOTchr1264833024+0.0006698070.99933016
ENST00000258149ENST00000332707MDM2chr1269222711+XPOTchr1264833024+0.0013103360.9986897
ENST00000258148ENST00000332707MDM2chr1269222711+XPOTchr1264833024+0.0010465070.99895346
ENST00000350057ENST00000332707MDM2chr1269222711+XPOTchr1264833024+0.0013161930.99868375
ENST00000462284ENST00000332707MDM2chr1269222711+XPOTchr1264838855+0.0027446240.9972554
ENST00000258149ENST00000332707MDM2chr1269222711+XPOTchr1264838855+0.0048979730.99510205
ENST00000258148ENST00000332707MDM2chr1269222711+XPOTchr1264838855+0.0039396580.9960603
ENST00000350057ENST00000332707MDM2chr1269222711+XPOTchr1264838855+0.0011237850.99887615

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Fusion Genomic Features for MDM2-XPOT


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MDM2-XPOT


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:69222710/chr12:64833023)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811210_215228498.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811210_215228498.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811210_215228498.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811210_215228498.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+6926_109167437.0DomainSWIB/MDM2
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+81126_109228498.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+6926_109167437.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+81126_109228498.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+6926_109167437.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+81126_109228498.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+6926_109167437.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+81126_109228498.0DomainSWIB/MDM2
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811179_185228498.0MotifNuclear localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811190_202228498.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811179_185228498.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811190_202228498.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811179_185228498.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811190_202228498.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811179_185228498.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811190_202228498.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+691_101167437.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+8111_101228498.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+691_101167437.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+8111_101228498.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+691_101167437.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+8111_101228498.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+691_101167437.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+8111_101228498.0RegionSufficient to promote the mitochondrial pathway of apoptosis

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69210_215167437.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69243_301167437.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15210_2150322.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15243_3010322.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13210_2150266.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13243_3010266.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16210_2150322.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16243_3010322.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14210_2150297.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14243_3010297.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13210_2150219.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13243_3010219.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12210_2150219.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12243_3010219.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14210_2150271.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14243_3010271.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811243_301228498.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15210_2150297.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15243_3010297.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69210_215167437.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69243_301167437.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15210_2150322.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15243_3010322.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13210_2150266.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13243_3010266.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16210_2150322.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16243_3010322.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14210_2150297.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14243_3010297.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13210_2150219.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13243_3010219.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12210_2150219.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12243_3010219.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14210_2150271.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14243_3010271.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811243_301228498.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15210_2150297.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15243_3010297.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69210_215167437.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69243_301167437.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15210_2150322.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15243_3010322.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13210_2150266.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13243_3010266.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16210_2150322.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16243_3010322.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14210_2150297.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14243_3010297.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13210_2150219.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13243_3010219.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12210_2150219.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12243_3010219.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14210_2150271.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14243_3010271.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811243_301228498.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15210_2150297.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15243_3010297.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69210_215167437.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69243_301167437.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15210_2150322.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15243_3010322.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13210_2150266.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13243_3010266.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16210_2150322.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16243_3010322.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14210_2150297.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14243_3010297.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13210_2150219.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13243_3010219.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12210_2150219.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12243_3010219.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14210_2150271.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14243_3010271.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811243_301228498.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15210_2150297.0Compositional biasNote=Poly-Ser
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15243_3010297.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+1526_1090322.0DomainSWIB/MDM2
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+1326_1090266.0DomainSWIB/MDM2
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+1626_1090322.0DomainSWIB/MDM2
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+1426_1090297.0DomainSWIB/MDM2
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+1326_1090219.0DomainSWIB/MDM2
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+1226_1090219.0DomainSWIB/MDM2
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+1426_1090271.0DomainSWIB/MDM2
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+1526_1090297.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+1526_1090322.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+1326_1090266.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+1626_1090322.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+1426_1090297.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+1326_1090219.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+1226_1090219.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+1426_1090271.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+1526_1090297.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+1526_1090322.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+1326_1090266.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+1626_1090322.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+1426_1090297.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+1326_1090219.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+1226_1090219.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+1426_1090271.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+1526_1090297.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+1526_1090322.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+1326_1090266.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+1626_1090322.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+1426_1090297.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+1326_1090219.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+1226_1090219.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+1426_1090271.0DomainSWIB/MDM2
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+1526_1090297.0DomainSWIB/MDM2
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69179_185167437.0MotifNuclear localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69190_202167437.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69466_473167437.0MotifNucleolar localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15179_1850322.0MotifNuclear localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15190_2020322.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15466_4730322.0MotifNucleolar localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13179_1850266.0MotifNuclear localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13190_2020266.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13466_4730266.0MotifNucleolar localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16179_1850322.0MotifNuclear localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16190_2020322.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16466_4730322.0MotifNucleolar localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14179_1850297.0MotifNuclear localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14190_2020297.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14466_4730297.0MotifNucleolar localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13179_1850219.0MotifNuclear localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13190_2020219.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13466_4730219.0MotifNucleolar localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12179_1850219.0MotifNuclear localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12190_2020219.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12466_4730219.0MotifNucleolar localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14179_1850271.0MotifNuclear localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14190_2020271.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14466_4730271.0MotifNucleolar localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811466_473228498.0MotifNucleolar localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15179_1850297.0MotifNuclear localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15190_2020297.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15466_4730297.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69179_185167437.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69190_202167437.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69466_473167437.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15179_1850322.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15190_2020322.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15466_4730322.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13179_1850266.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13190_2020266.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13466_4730266.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16179_1850322.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16190_2020322.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16466_4730322.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14179_1850297.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14190_2020297.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14466_4730297.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13179_1850219.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13190_2020219.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13466_4730219.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12179_1850219.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12190_2020219.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12466_4730219.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14179_1850271.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14190_2020271.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14466_4730271.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811466_473228498.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15179_1850297.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15190_2020297.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15466_4730297.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69179_185167437.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69190_202167437.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69466_473167437.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15179_1850322.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15190_2020322.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15466_4730322.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13179_1850266.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13190_2020266.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13466_4730266.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16179_1850322.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16190_2020322.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16466_4730322.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14179_1850297.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14190_2020297.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14466_4730297.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13179_1850219.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13190_2020219.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13466_4730219.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12179_1850219.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12190_2020219.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12466_4730219.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14179_1850271.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14190_2020271.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14466_4730271.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811466_473228498.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15179_1850297.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15190_2020297.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15466_4730297.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69179_185167437.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69190_202167437.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69466_473167437.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15179_1850322.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15190_2020322.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15466_4730322.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13179_1850266.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13190_2020266.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13466_4730266.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16179_1850322.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16190_2020322.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16466_4730322.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14179_1850297.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14190_2020297.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14466_4730297.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13179_1850219.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13190_2020219.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13466_4730219.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12179_1850219.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12190_2020219.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12466_4730219.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14179_1850271.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14190_2020271.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14466_4730271.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811466_473228498.0MotifNucleolar localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15179_1850297.0MotifNuclear localization signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15190_2020297.0MotifNote=Nuclear export signal
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15466_4730297.0MotifNucleolar localization signal
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69210_304167437.0RegionNote=ARF-binding
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69242_331167437.0RegionNote=Region II
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+151_1010322.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15210_3040322.0RegionNote=ARF-binding
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15242_3310322.0RegionNote=Region II
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+131_1010266.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13210_3040266.0RegionNote=ARF-binding
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13242_3310266.0RegionNote=Region II
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+161_1010322.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16210_3040322.0RegionNote=ARF-binding
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16242_3310322.0RegionNote=Region II
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+141_1010297.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14210_3040297.0RegionNote=ARF-binding
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14242_3310297.0RegionNote=Region II
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+131_1010219.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13210_3040219.0RegionNote=ARF-binding
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13242_3310219.0RegionNote=Region II
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+121_1010219.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12210_3040219.0RegionNote=ARF-binding
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12242_3310219.0RegionNote=Region II
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+141_1010271.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14210_3040271.0RegionNote=ARF-binding
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14242_3310271.0RegionNote=Region II
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811210_304228498.0RegionNote=ARF-binding
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811242_331228498.0RegionNote=Region II
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+151_1010297.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15210_3040297.0RegionNote=ARF-binding
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15242_3310297.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69210_304167437.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69242_331167437.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+151_1010322.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15210_3040322.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15242_3310322.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+131_1010266.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13210_3040266.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13242_3310266.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+161_1010322.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16210_3040322.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16242_3310322.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+141_1010297.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14210_3040297.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14242_3310297.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+131_1010219.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13210_3040219.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13242_3310219.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+121_1010219.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12210_3040219.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12242_3310219.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+141_1010271.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14210_3040271.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14242_3310271.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811210_304228498.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811242_331228498.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+151_1010297.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15210_3040297.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15242_3310297.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69210_304167437.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69242_331167437.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+151_1010322.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15210_3040322.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15242_3310322.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+131_1010266.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13210_3040266.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13242_3310266.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+161_1010322.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16210_3040322.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16242_3310322.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+141_1010297.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14210_3040297.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14242_3310297.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+131_1010219.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13210_3040219.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13242_3310219.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+121_1010219.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12210_3040219.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12242_3310219.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+141_1010271.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14210_3040271.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14242_3310271.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811210_304228498.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811242_331228498.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+151_1010297.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15210_3040297.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15242_3310297.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69210_304167437.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69242_331167437.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+151_1010322.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15210_3040322.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15242_3310322.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+131_1010266.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13210_3040266.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13242_3310266.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+161_1010322.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16210_3040322.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16242_3310322.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+141_1010297.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14210_3040297.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14242_3310297.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+131_1010219.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13210_3040219.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13242_3310219.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+121_1010219.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12210_3040219.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12242_3310219.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+141_1010271.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14210_3040271.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14242_3310271.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811210_304228498.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811242_331228498.0RegionNote=Region II
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+151_1010297.0RegionSufficient to promote the mitochondrial pathway of apoptosis
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15210_3040297.0RegionNote=ARF-binding
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15242_3310297.0RegionNote=Region II
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69299_328167437.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69438_479167437.0Zinc fingerRING-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15299_3280322.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15438_4790322.0Zinc fingerRING-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13299_3280266.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13438_4790266.0Zinc fingerRING-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16299_3280322.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16438_4790322.0Zinc fingerRING-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14299_3280297.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14438_4790297.0Zinc fingerRING-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13299_3280219.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13438_4790219.0Zinc fingerRING-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12299_3280219.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12438_4790219.0Zinc fingerRING-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14299_3280271.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14438_4790271.0Zinc fingerRING-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811299_328228498.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811438_479228498.0Zinc fingerRING-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15299_3280297.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15438_4790297.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69299_328167437.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69438_479167437.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15299_3280322.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15438_4790322.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13299_3280266.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13438_4790266.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16299_3280322.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16438_4790322.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14299_3280297.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14438_4790297.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13299_3280219.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13438_4790219.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12299_3280219.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12438_4790219.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14299_3280271.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14438_4790271.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811299_328228498.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811438_479228498.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15299_3280297.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15438_4790297.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69299_328167437.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69438_479167437.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15299_3280322.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15438_4790322.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13299_3280266.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13438_4790266.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16299_3280322.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16438_4790322.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14299_3280297.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14438_4790297.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13299_3280219.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13438_4790219.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12299_3280219.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12438_4790219.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14299_3280271.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14438_4790271.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811299_328228498.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811438_479228498.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15299_3280297.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15438_4790297.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69299_328167437.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69438_479167437.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15299_3280322.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15438_4790322.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13299_3280266.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13438_4790266.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16299_3280322.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16438_4790322.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14299_3280297.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14438_4790297.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13299_3280219.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13438_4790219.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12299_3280219.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12438_4790219.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14299_3280271.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14438_4790271.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811299_328228498.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811438_479228498.0Zinc fingerRING-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15299_3280297.0Zinc fingerRanBP2-type
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15438_4790297.0Zinc fingerRING-type
TgeneXPOTchr12:69222710chr12:64833023ENST000003327072125443_962911963.0RegionNote=Necessary for tRNA-binding%2C cytoplasmic localization and nuclear export
TgeneXPOTchr12:69222711chr12:64833023ENST000003327072125443_962911963.0RegionNote=Necessary for tRNA-binding%2C cytoplasmic localization and nuclear export
TgeneXPOTchr12:69222711chr12:64833024ENST000003327072125443_962911963.0RegionNote=Necessary for tRNA-binding%2C cytoplasmic localization and nuclear export
TgeneXPOTchr12:69222711chr12:64838855ENST000003327072225443_962935963.0RegionNote=Necessary for tRNA-binding%2C cytoplasmic localization and nuclear export


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Fusion Gene Sequence for MDM2-XPOT


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>52427_52427_1_MDM2-XPOT_MDM2_chr12_69222710_ENST00000258148_XPOT_chr12_64833023_ENST00000332707_length(transcript)=3685nt_BP=533nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC
CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA
TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG
ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG
TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG
AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCCCAG
AATGTGTTCAGTATCTTCAACAAGAATACCTGCCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGCAGC
CTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCATGAT
CATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTATAT
GTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAATTGT
TCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTATAAA
GACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAAGTA
TGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAAAAG
AGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTTCTG
GAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGGATG
CTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAAAGC
CTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGCAGG
TGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGATGG
TGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATTGTG
CCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACTCTT
TTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTAGAA
GTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGGAAA
GAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAGGGT
TTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGTACA
TTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTATAA
AAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGTTCC
CCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAAGAG
TTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTAAAG
AATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAACTTG
AAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATAGTG
TATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTCACT
GTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACATTT
TTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAATGTT
GGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTTAAA
GCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCATGTT
ATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTTATT
TCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTGACT
AGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGTTGG
TTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAACTTT
GAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTGTAA

>52427_52427_1_MDM2-XPOT_MDM2_chr12_69222710_ENST00000258148_XPOT_chr12_64833023_ENST00000332707_length(amino acids)=224AA_BP=173
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGD
LFGVPSFSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPGPECVQY

--------------------------------------------------------------
>52427_52427_2_MDM2-XPOT_MDM2_chr12_69222710_ENST00000258149_XPOT_chr12_64833023_ENST00000332707_length(transcript)=3958nt_BP=806nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA
ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG
TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCC
CAGAATGTGTTCAGTATCTTCAACAAGAATACCTGCCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGC
AGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCAT
GATCATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTA
TATGTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAAT
TGTTCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTAT
AAAGACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAA
GTATGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAA
AAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTT
CTGGAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGG
ATGCTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAA
AGCCTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGC
AGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGA
TGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATT
GTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACT
CTTTTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTA
GAAGTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGG
AAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAG
GGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGT
ACATTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTA
TAAAAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGT
TCCCCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAA
GAGTTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTA
AAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAAC
TTGAAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATA
GTGTATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTC
ACTGTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACA
TTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAAT
GTTGGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTT
AAAGCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCAT
GTTATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTT
ATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTG
ACTAGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGT
TGGTTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAAC
TTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTG

>52427_52427_2_MDM2-XPOT_MDM2_chr12_69222710_ENST00000258149_XPOT_chr12_64833023_ENST00000332707_length(amino acids)=236AA_BP=185
MRDPRLQARKPRMVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQ
HIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTG

--------------------------------------------------------------
>52427_52427_3_MDM2-XPOT_MDM2_chr12_69222710_ENST00000350057_XPOT_chr12_64833023_ENST00000332707_length(transcript)=3743nt_BP=591nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCCCAGAATGTGTTCAGTATCTTCAACAAGAATACCTG
CCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGCAGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAG
GTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCATGATCATGAATTCCAGTTAATTTATAAAGAGGCGAT
TTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTATATGTTTTGGGATTTTTCTGTAAAATGGGTGTAAT
TTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAATTGTTCTGTATAAAGATGCTCTTAAAAGACACAAGA
GTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTATAAAGACCATAGCAGTGGAAAACAGTGTACTTTTTA
AAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAAGTATGGGGGAAGACAGCAATCAAAACTAACTTTTT
GTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAAAAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTT
TTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTTCTGGAATTATTATAAATACTTTAGTTTTATTTTCT
CATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGGATGCTTTAATTCATTTAACCTCACTCCTCAAAGGT
AACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAAAGCCTATGTGAATCTGTTGATAGAATTTAAAATTC
CAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAG
CCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGATGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGC
TGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAG
ACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACTCTTTTATTGGATGTATTTAGAACACAGTATACCTA
TAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTAGAAGTACTTACCCCTGCCTTCCTCCATTTTTATTC
ATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGGAAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAA
TTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAGGGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTT
CATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGTACATTTATTTTGTTCCGGTTAATTCCAGAAGACAT
TTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTATAAAAATAAATCAGTGAAATGTACCTTATACTTTA
ATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGTTCCCCTGTACTATAGGAGTGATAATTGCAGCTATT
GCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAAGAGTTTATATAGCACAGGCTCTAGAATCAGATTAA
GTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTAAAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTA
AAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAACTTGAAAAGACTTATTACAGTAGCTGGCACATAAAG
ACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATAGTGTATCACTATACTTTTTTTTTCTTTTTTTTTTT
TGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTCACTGTAACTTCTCCCATACTCTACCAATCCTCCTG
CCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACATTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTA
CCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAATGTTGGGATTACAGGTATAAGCCACTGCACACGGCC
TTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTTAAAGCTCTGCAGAAGATTTACATGTGTTTATAGAG
CTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCATGTTATATAATCATGCATAACTTCTATCTTCATTCT
CTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTTATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAA
GAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTGACTAGGGAACCACAAGTTTTCATATAATGCCTGAT
TTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGTTGGTTGACCTTATAAGAAAACACTGTGTGGTATTT
TAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAACTTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTT
AACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTGTAAGCAGTGAATAGATGTGTTGTTAGAATGATTCC

>52427_52427_3_MDM2-XPOT_MDM2_chr12_69222710_ENST00000350057_XPOT_chr12_64833023_ENST00000332707_length(amino acids)=248AA_BP=197
MCNTNMSVPTDGAVTTSQIPASEQETLVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQES
SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI

--------------------------------------------------------------
>52427_52427_4_MDM2-XPOT_MDM2_chr12_69222710_ENST00000462284_XPOT_chr12_64833023_ENST00000332707_length(transcript)=4138nt_BP=986nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG
TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC
AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA
TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT
ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG
ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG
CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCC
CAGAATGTGTTCAGTATCTTCAACAAGAATACCTGCCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGC
AGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCAT
GATCATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTA
TATGTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAAT
TGTTCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTAT
AAAGACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAA
GTATGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAA
AAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTT
CTGGAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGG
ATGCTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAA
AGCCTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGC
AGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGA
TGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATT
GTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACT
CTTTTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTA
GAAGTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGG
AAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAG
GGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGT
ACATTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTA
TAAAAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGT
TCCCCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAA
GAGTTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTA
AAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAAC
TTGAAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATA
GTGTATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTC
ACTGTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACA
TTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAAT
GTTGGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTT
AAAGCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCAT
GTTATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTT
ATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTG
ACTAGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGT
TGGTTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAAC
TTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTG

>52427_52427_4_MDM2-XPOT_MDM2_chr12_69222710_ENST00000462284_XPOT_chr12_64833023_ENST00000332707_length(amino acids)=291AA_BP=240
MRDPRLQARKPRMVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQ
HIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRR
RAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPGPECVQYLQQEYLPSLQVAPEIIQEFCQAL

--------------------------------------------------------------
>52427_52427_5_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258148_XPOT_chr12_64833023_ENST00000332707_length(transcript)=3685nt_BP=533nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC
CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA
TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG
ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG
TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG
AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCCCAG
AATGTGTTCAGTATCTTCAACAAGAATACCTGCCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGCAGC
CTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCATGAT
CATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTATAT
GTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAATTGT
TCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTATAAA
GACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAAGTA
TGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAAAAG
AGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTTCTG
GAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGGATG
CTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAAAGC
CTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGCAGG
TGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGATGG
TGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATTGTG
CCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACTCTT
TTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTAGAA
GTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGGAAA
GAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAGGGT
TTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGTACA
TTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTATAA
AAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGTTCC
CCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAAGAG
TTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTAAAG
AATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAACTTG
AAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATAGTG
TATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTCACT
GTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACATTT
TTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAATGTT
GGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTTAAA
GCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCATGTT
ATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTTATT
TCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTGACT
AGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGTTGG
TTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAACTTT
GAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTGTAA

>52427_52427_5_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258148_XPOT_chr12_64833023_ENST00000332707_length(amino acids)=224AA_BP=173
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGD
LFGVPSFSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPGPECVQY

--------------------------------------------------------------
>52427_52427_6_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258148_XPOT_chr12_64833024_ENST00000332707_length(transcript)=3685nt_BP=533nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC
CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA
TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG
ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG
TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG
AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCCCAG
AATGTGTTCAGTATCTTCAACAAGAATACCTGCCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGCAGC
CTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCATGAT
CATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTATAT
GTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAATTGT
TCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTATAAA
GACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAAGTA
TGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAAAAG
AGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTTCTG
GAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGGATG
CTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAAAGC
CTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGCAGG
TGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGATGG
TGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATTGTG
CCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACTCTT
TTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTAGAA
GTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGGAAA
GAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAGGGT
TTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGTACA
TTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTATAA
AAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGTTCC
CCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAAGAG
TTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTAAAG
AATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAACTTG
AAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATAGTG
TATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTCACT
GTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACATTT
TTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAATGTT
GGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTTAAA
GCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCATGTT
ATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTTATT
TCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTGACT
AGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGTTGG
TTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAACTTT
GAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTGTAA

>52427_52427_6_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258148_XPOT_chr12_64833024_ENST00000332707_length(amino acids)=224AA_BP=173
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGD
LFGVPSFSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPGPECVQY

--------------------------------------------------------------
>52427_52427_7_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258148_XPOT_chr12_64838855_ENST00000332707_length(transcript)=3613nt_BP=533nt
CGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTC
CAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATACTA
TGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATG
ATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAG
TCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATG
AAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGAGTTTT
GTCAAGCGCTTCAGCAGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCC
CTGTGCCTACTTCATGATCATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTT
GAGCTTATTGCAGTATATGTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTG
CATGCCGGTCCAAATTGTTCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTA
AGTCAAGTCCTTTATAAAGACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTAT
GTGTGAAGACACAAAGTATGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCA
ATATGTATTCTACAAAAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTGAAA
TCTTCCAAGTCTTTTCTGGAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACA
AATATGAGTGTGTGGATGCTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTT
TAATGTACTGGAAAAAGCCTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACT
TTGGGAGGCCAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATAC
AACAGCCAGGTGTGATGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTG
CAGTGAGCTGAGATTGTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCA
ATTTATTTTCTAACTCTTTTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACT
GACATTTAATTATTAGAAGTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTAT
CAGTAGTGTCACTGGAAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATT
GAGATGTTCAGGGAGGGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTC
TATTCTAAATTTTGTACATTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACTTAA
CTAAATTGACAGTTATAAAAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGT
GTTTCTTTGATAGGTTCCCCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCA
TAGCATAGTGGGTAAGAGTTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGA
ACCTTGGGCAAGTTAAAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAA
TTCAATGAGTTAAACTTGAAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCA
TATATGGAATTAATAGTGTATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTG
GTGACATCATAGCTCACTGTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCA
CCACACCCAGCTACATTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCC
CACTGGCCTCACAATGTTGGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCC
CTTTCAGAGCTCTTTAAAGCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAA
AATTAAACTCTTCATGTTATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCC
ATCATGAATTACCTTATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGG
GATTTGTTTGACTTGACTAGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGT
TAATTGCTTCCCAGTTGGTTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTT
AATCACTCCCACAACTTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGA
AATTAGTTGGAATTGTAAGCAGTGAATAGATGTGTTGTTAGAATGATTCCATCACTTATACATTGTTTAAAATGCTAATAAAGTAACTTG

>52427_52427_7_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258148_XPOT_chr12_64838855_ENST00000332707_length(amino acids)=200AA_BP=173
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGD
LFGVPSFSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPEFCQALQ

--------------------------------------------------------------
>52427_52427_8_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258149_XPOT_chr12_64833023_ENST00000332707_length(transcript)=3958nt_BP=806nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA
ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG
TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCC
CAGAATGTGTTCAGTATCTTCAACAAGAATACCTGCCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGC
AGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCAT
GATCATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTA
TATGTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAAT
TGTTCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTAT
AAAGACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAA
GTATGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAA
AAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTT
CTGGAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGG
ATGCTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAA
AGCCTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGC
AGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGA
TGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATT
GTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACT
CTTTTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTA
GAAGTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGG
AAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAG
GGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGT
ACATTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTA
TAAAAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGT
TCCCCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAA
GAGTTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTA
AAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAAC
TTGAAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATA
GTGTATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTC
ACTGTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACA
TTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAAT
GTTGGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTT
AAAGCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCAT
GTTATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTT
ATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTG
ACTAGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGT
TGGTTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAAC
TTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTG

>52427_52427_8_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258149_XPOT_chr12_64833023_ENST00000332707_length(amino acids)=236AA_BP=185
MRDPRLQARKPRMVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQ
HIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTG

--------------------------------------------------------------
>52427_52427_9_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258149_XPOT_chr12_64833024_ENST00000332707_length(transcript)=3958nt_BP=806nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA
ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG
TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCC
CAGAATGTGTTCAGTATCTTCAACAAGAATACCTGCCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGC
AGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCAT
GATCATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTA
TATGTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAAT
TGTTCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTAT
AAAGACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAA
GTATGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAA
AAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTT
CTGGAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGG
ATGCTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAA
AGCCTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGC
AGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGA
TGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATT
GTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACT
CTTTTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTA
GAAGTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGG
AAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAG
GGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGT
ACATTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTA
TAAAAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGT
TCCCCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAA
GAGTTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTA
AAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAAC
TTGAAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATA
GTGTATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTC
ACTGTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACA
TTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAAT
GTTGGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTT
AAAGCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCAT
GTTATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTT
ATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTG
ACTAGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGT
TGGTTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAAC
TTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTG

>52427_52427_9_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258149_XPOT_chr12_64833024_ENST00000332707_length(amino acids)=236AA_BP=185
MRDPRLQARKPRMVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQ
HIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTG

--------------------------------------------------------------
>52427_52427_10_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258149_XPOT_chr12_64838855_ENST00000332707_length(transcript)=3886nt_BP=806nt
GCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGCCCGAGGGGCGGCCGC
GACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGCCCAGTGCCCTGGCCC
GGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGAGGGACCCCCGACTCC
AAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGA
TTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCACAAAAAGACACTTATA
CTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAA
ATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAG
TAGTCAATCAGCAGGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGAGT
TTTGTCAAGCGCTTCAGCAGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATT
TCCCTGTGCCTACTTCATGATCATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGT
TTTGAGCTTATTGCAGTATATGTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGC
CTGCATGCCGGTCCAAATTGTTCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATT
TTAAGTCAAGTCCTTTATAAAGACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTT
TATGTGTGAAGACACAAAGTATGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACG
CCAATATGTATTCTACAAAAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTG
AAATCTTCCAAGTCTTTTCTGGAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTT
ACAAATATGAGTGTGTGGATGCTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTT
CTTTAATGTACTGGAAAAAGCCTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGA
ACTTTGGGAGGCCAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAA
TACAACAGCCAGGTGTGATGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGG
TTGCAGTGAGCTGAGATTGTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATC
CCAATTTATTTTCTAACTCTTTTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTA
ACTGACATTTAATTATTAGAAGTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGT
TATCAGTAGTGTCACTGGAAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCA
ATTGAGATGTTCAGGGAGGGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAA
TTCTATTCTAAATTTTGTACATTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACT
TAACTAAATTGACAGTTATAAAAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTG
AGTGTTTCTTTGATAGGTTCCCCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATA
GCATAGCATAGTGGGTAAGAGTTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTT
AGAACCTTGGGCAAGTTAAAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTAC
GAATTCAATGAGTTAAACTTGAAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTA
GCATATATGGAATTAATAGTGTATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCA
GTGGTGACATCATAGCTCACTGTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCA
CCACCACACCCAGCTACATTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCC
TCCCACTGGCCTCACAATGTTGGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTT
TCCCTTTCAGAGCTCTTTAAAGCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAAT
AAAAATTAAACTCTTCATGTTATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCT
TCCATCATGAATTACCTTATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTT
GGGGATTTGTTTGACTTGACTAGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAA
TGTTAATTGCTTCCCAGTTGGTTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCA
GTTAATCACTCCCACAACTTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAAC
TGAAATTAGTTGGAATTGTAAGCAGTGAATAGATGTGTTGTTAGAATGATTCCATCACTTATACATTGTTTAAAATGCTAATAAAGTAAC

>52427_52427_10_MDM2-XPOT_MDM2_chr12_69222711_ENST00000258149_XPOT_chr12_64838855_ENST00000332707_length(amino acids)=212AA_BP=185
MRDPRLQARKPRMVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQ
HIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTG

--------------------------------------------------------------
>52427_52427_11_MDM2-XPOT_MDM2_chr12_69222711_ENST00000350057_XPOT_chr12_64833023_ENST00000332707_length(transcript)=3743nt_BP=591nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCCCAGAATGTGTTCAGTATCTTCAACAAGAATACCTG
CCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGCAGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAG
GTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCATGATCATGAATTCCAGTTAATTTATAAAGAGGCGAT
TTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTATATGTTTTGGGATTTTTCTGTAAAATGGGTGTAAT
TTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAATTGTTCTGTATAAAGATGCTCTTAAAAGACACAAGA
GTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTATAAAGACCATAGCAGTGGAAAACAGTGTACTTTTTA
AAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAAGTATGGGGGAAGACAGCAATCAAAACTAACTTTTT
GTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAAAAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTT
TTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTTCTGGAATTATTATAAATACTTTAGTTTTATTTTCT
CATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGGATGCTTTAATTCATTTAACCTCACTCCTCAAAGGT
AACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAAAGCCTATGTGAATCTGTTGATAGAATTTAAAATTC
CAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAG
CCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGATGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGC
TGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAG
ACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACTCTTTTATTGGATGTATTTAGAACACAGTATACCTA
TAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTAGAAGTACTTACCCCTGCCTTCCTCCATTTTTATTC
ATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGGAAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAA
TTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAGGGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTT
CATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGTACATTTATTTTGTTCCGGTTAATTCCAGAAGACAT
TTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTATAAAAATAAATCAGTGAAATGTACCTTATACTTTA
ATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGTTCCCCTGTACTATAGGAGTGATAATTGCAGCTATT
GCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAAGAGTTTATATAGCACAGGCTCTAGAATCAGATTAA
GTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTAAAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTA
AAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAACTTGAAAAGACTTATTACAGTAGCTGGCACATAAAG
ACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATAGTGTATCACTATACTTTTTTTTTCTTTTTTTTTTT
TGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTCACTGTAACTTCTCCCATACTCTACCAATCCTCCTG
CCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACATTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTA
CCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAATGTTGGGATTACAGGTATAAGCCACTGCACACGGCC
TTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTTAAAGCTCTGCAGAAGATTTACATGTGTTTATAGAG
CTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCATGTTATATAATCATGCATAACTTCTATCTTCATTCT
CTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTTATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAA
GAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTGACTAGGGAACCACAAGTTTTCATATAATGCCTGAT
TTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGTTGGTTGACCTTATAAGAAAACACTGTGTGGTATTT
TAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAACTTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTT
AACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTGTAAGCAGTGAATAGATGTGTTGTTAGAATGATTCC

>52427_52427_11_MDM2-XPOT_MDM2_chr12_69222711_ENST00000350057_XPOT_chr12_64833023_ENST00000332707_length(amino acids)=248AA_BP=197
MCNTNMSVPTDGAVTTSQIPASEQETLVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQES
SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI

--------------------------------------------------------------
>52427_52427_12_MDM2-XPOT_MDM2_chr12_69222711_ENST00000350057_XPOT_chr12_64833024_ENST00000332707_length(transcript)=3743nt_BP=591nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCCCAGAATGTGTTCAGTATCTTCAACAAGAATACCTG
CCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGCAGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAG
GTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCATGATCATGAATTCCAGTTAATTTATAAAGAGGCGAT
TTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTATATGTTTTGGGATTTTTCTGTAAAATGGGTGTAAT
TTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAATTGTTCTGTATAAAGATGCTCTTAAAAGACACAAGA
GTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTATAAAGACCATAGCAGTGGAAAACAGTGTACTTTTTA
AAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAAGTATGGGGGAAGACAGCAATCAAAACTAACTTTTT
GTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAAAAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTT
TTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTTCTGGAATTATTATAAATACTTTAGTTTTATTTTCT
CATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGGATGCTTTAATTCATTTAACCTCACTCCTCAAAGGT
AACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAAAGCCTATGTGAATCTGTTGATAGAATTTAAAATTC
CAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAG
CCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGATGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGC
TGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAG
ACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACTCTTTTATTGGATGTATTTAGAACACAGTATACCTA
TAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTAGAAGTACTTACCCCTGCCTTCCTCCATTTTTATTC
ATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGGAAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAA
TTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAGGGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTT
CATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGTACATTTATTTTGTTCCGGTTAATTCCAGAAGACAT
TTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTATAAAAATAAATCAGTGAAATGTACCTTATACTTTA
ATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGTTCCCCTGTACTATAGGAGTGATAATTGCAGCTATT
GCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAAGAGTTTATATAGCACAGGCTCTAGAATCAGATTAA
GTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTAAAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTA
AAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAACTTGAAAAGACTTATTACAGTAGCTGGCACATAAAG
ACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATAGTGTATCACTATACTTTTTTTTTCTTTTTTTTTTT
TGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTCACTGTAACTTCTCCCATACTCTACCAATCCTCCTG
CCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACATTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTA
CCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAATGTTGGGATTACAGGTATAAGCCACTGCACACGGCC
TTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTTAAAGCTCTGCAGAAGATTTACATGTGTTTATAGAG
CTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCATGTTATATAATCATGCATAACTTCTATCTTCATTCT
CTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTTATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAA
GAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTGACTAGGGAACCACAAGTTTTCATATAATGCCTGAT
TTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGTTGGTTGACCTTATAAGAAAACACTGTGTGGTATTT
TAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAACTTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTT
AACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTGTAAGCAGTGAATAGATGTGTTGTTAGAATGATTCC

>52427_52427_12_MDM2-XPOT_MDM2_chr12_69222711_ENST00000350057_XPOT_chr12_64833024_ENST00000332707_length(amino acids)=248AA_BP=197
MCNTNMSVPTDGAVTTSQIPASEQETLVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQES
SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI

--------------------------------------------------------------
>52427_52427_13_MDM2-XPOT_MDM2_chr12_69222711_ENST00000350057_XPOT_chr12_64838855_ENST00000332707_length(transcript)=3671nt_BP=591nt
ATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTGTAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTCTTTTT
TATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATATTGTATATTGTTCAAATGATCTTCTAGGAGATTTG
TTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCTACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCA
TCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTGATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAG
AAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAGCAATTAGTGAGACAGAAGAAAATTCAGATGAATTA
TCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTGATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATA
TGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGAGTTTTGTCAAGCGCTTCAGCAGCCTGATGCTAAAGTT
TTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCATGATCATGAATTCCAGTT
AATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTATATGTTTTGGGATTTTT
CTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAATTGTTCTGTATAAAGATG
CTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTATAAAGACCATAGCAGTGG
AAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAAGTATGGGGGAAGACAGC
AATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAAAAGAGAATGGTTTTAGG
CTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTTCTGGAATTATTATAAAT
ACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGGATGCTTTAATTCATTTA
ACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAAAGCCTATGTGAATCTGT
TGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGCAGGTGGATCACTTGAGG
TCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGATGGTGCACGCTCGTAAT
CCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATTGTGCCACTGCACGCCAG
CCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACTCTTTTATTGGATGTATT
TAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTAGAAGTACTTACCCCTGC
CTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGGAAAGAAGAGAGGAGGGA
CAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAGGGTTTGTTTTGCCCTTT
GGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGTACATTTATTTTGTTCCG
GTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTATAAAAATAAATCAGTGA
AATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGTTCCCCTGTACTATAGGA
GTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAAGAGTTTATATAGCACAG
GCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTAAAGAATGTCTCCCAGCC
TCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAACTTGAAAAGACTTATTAC
AGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATAGTGTATCACTATACTTT
TTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTCACTGTAACTTCTCCCAT
ACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACATTTTTTTTTGGTAGAGA
CAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAATGTTGGGATTACAGGTAT
AAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTTAAAGCTCTGCAGAAGAT
TTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCATGTTATATAATCATGCAT
AACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTTATTTCCAAAAGCAAGTA
CTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTGACTAGGGAACCACAAGT
TTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGTTGGTTGACCTTATAAGA
AAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAACTTTGAGCTGTGAGTTTT
ACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTGTAAGCAGTGAATAGATG

>52427_52427_13_MDM2-XPOT_MDM2_chr12_69222711_ENST00000350057_XPOT_chr12_64838855_ENST00000332707_length(amino acids)=224AA_BP=197
MCNTNMSVPTDGAVTTSQIPASEQETLVLFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQES
SDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREI

--------------------------------------------------------------
>52427_52427_14_MDM2-XPOT_MDM2_chr12_69222711_ENST00000462284_XPOT_chr12_64833023_ENST00000332707_length(transcript)=4138nt_BP=986nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG
TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC
AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA
TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT
ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG
ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG
CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCC
CAGAATGTGTTCAGTATCTTCAACAAGAATACCTGCCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGC
AGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCAT
GATCATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTA
TATGTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAAT
TGTTCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTAT
AAAGACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAA
GTATGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAA
AAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTT
CTGGAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGG
ATGCTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAA
AGCCTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGC
AGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGA
TGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATT
GTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACT
CTTTTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTA
GAAGTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGG
AAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAG
GGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGT
ACATTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTA
TAAAAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGT
TCCCCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAA
GAGTTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTA
AAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAAC
TTGAAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATA
GTGTATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTC
ACTGTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACA
TTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAAT
GTTGGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTT
AAAGCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCAT
GTTATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTT
ATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTG
ACTAGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGT
TGGTTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAAC
TTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTG

>52427_52427_14_MDM2-XPOT_MDM2_chr12_69222711_ENST00000462284_XPOT_chr12_64833023_ENST00000332707_length(amino acids)=291AA_BP=240
MRDPRLQARKPRMVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQ
HIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRR
RAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPGPECVQYLQQEYLPSLQVAPEIIQEFCQAL

--------------------------------------------------------------
>52427_52427_15_MDM2-XPOT_MDM2_chr12_69222711_ENST00000462284_XPOT_chr12_64833024_ENST00000332707_length(transcript)=4138nt_BP=986nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG
TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC
AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA
TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT
ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG
ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG
CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGGCC
CAGAATGTGTTCAGTATCTTCAACAAGAATACCTGCCCTCCTTGCAAGTAGCTCCAGAAATAATTCAGGAGTTTTGTCAAGCGCTTCAGC
AGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATTTCCCTGTGCCTACTTCAT
GATCATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGTTTTGAGCTTATTGCAGTA
TATGTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGCCTGCATGCCGGTCCAAAT
TGTTCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATTTTAAGTCAAGTCCTTTAT
AAAGACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTTTATGTGTGAAGACACAAA
GTATGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACGCCAATATGTATTCTACAA
AAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTGAAATCTTCCAAGTCTTTT
CTGGAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTTACAAATATGAGTGTGTGG
ATGCTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTTCTTTAATGTACTGGAAAA
AGCCTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGAACTTTGGGAGGCCAAGGC
AGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAACAGCCAGGTGTGA
TGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGGTTGCAGTGAGCTGAGATT
GTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATCCCAATTTATTTTCTAACT
CTTTTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTAACTGACATTTAATTATTA
GAAGTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGTTATCAGTAGTGTCACTGG
AAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCAATTGAGATGTTCAGGGAG
GGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAATTCTATTCTAAATTTTGT
ACATTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACTTAACTAAATTGACAGTTA
TAAAAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTGAGTGTTTCTTTGATAGGT
TCCCCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATAGCATAGCATAGTGGGTAA
GAGTTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTTAGAACCTTGGGCAAGTTA
AAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTACGAATTCAATGAGTTAAAC
TTGAAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTAGCATATATGGAATTAATA
GTGTATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCAGTGGTGACATCATAGCTC
ACTGTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCACCACCACACCCAGCTACA
TTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCCTCCCACTGGCCTCACAAT
GTTGGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTTTCCCTTTCAGAGCTCTTT
AAAGCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAATAAAAATTAAACTCTTCAT
GTTATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCTTCCATCATGAATTACCTT
ATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTTGGGGATTTGTTTGACTTG
ACTAGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAATGTTAATTGCTTCCCAGT
TGGTTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCAGTTAATCACTCCCACAAC
TTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAACTGAAATTAGTTGGAATTG

>52427_52427_15_MDM2-XPOT_MDM2_chr12_69222711_ENST00000462284_XPOT_chr12_64833024_ENST00000332707_length(amino acids)=291AA_BP=240
MRDPRLQARKPRMVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQ
HIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRR
RAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPGPECVQYLQQEYLPSLQVAPEIIQEFCQAL

--------------------------------------------------------------
>52427_52427_16_MDM2-XPOT_MDM2_chr12_69222711_ENST00000462284_XPOT_chr12_64838855_ENST00000332707_length(transcript)=4066nt_BP=986nt
GGGGCGCGCACCGAGGCACCGCGGCGAGCTTGGCTGCTTCTGGGGCCTGTGTGGCCCTGTGTGTCGGAAAGATGGAGCAAGAAGCCGAGC
CCGAGGGGCGGCCGCGACCCCTCTGACCGAGATCCTGCTGCTTTCGCAGCCAGGAGCACCGTCCCTCCCCGGATTAGTGCGTACGAGCGC
CCAGTGCCCTGGCCCGGAGAGTGGAATGATCCCCGAGGCCCAGGGCGTCGTGCTTCCGCGCGCCCCGTGAAGGAAACTGGGGAGTCTTGA
GGGACCCCCGACTCCAAGCGCGAAAACCCCGGATGGTGAGGAGCAGGCAAATGTGCAATACCAACATGTCTGTACCTACTGATGGTGCTG
TAACCACCTCACAGATTCCAGCTTCGGAACAAGAGACCCTGGTTAGACCAAAGCCATTGCTTTTGAAGTTATTAAAGTCTGTTGGTGCAC
AAAAAGACACTTATACTATGAAAGAGGTTCTTTTTTATCTTGGCCAGTATATTATGACTAAACGATTATATGATGAGAAGCAACAACATA
TTGTATATTGTTCAAATGATCTTCTAGGAGATTTGTTTGGCGTGCCAAGCTTCTCTGTGAAAGAGCACAGGAAAATATATACCATGATCT
ACAGGAACTTGGTAGTAGTCAATCAGCAGGAATCATCGGACTCAGGTACATCTGTGAGTGAGAACAGGTGTCACCTTGAAGGTGGGAGTG
ATCAAAAGGACCTTGTACAAGAGCTTCAGGAAGAGAAACCTTCATCTTCACATTTGGTTTCTAGACCATCTACCTCATCTAGAAGGAGAG
CAATTAGTGAGACAGAAGAAAATTCAGATGAATTATCTGGTGAACGACAAAGAAAACGCCACAAATCTGATAGTATTTCCCTTTCCTTTG
ATGAAAGCCTGGCTCTGTGTGTAATAAGGGAGATATGTTGTGAAAGAAGCAGTAGCAGTGAATCTACAGGGACGCCATCGAATCCGGAGT
TTTGTCAAGCGCTTCAGCAGCCTGATGCTAAAGTTTTTAAAAATTACTTAAAGGTGTTCTTCCAGAGAGCAAAGCCCTGAGGACTGGATT
TCCCTGTGCCTACTTCATGATCATGAATTCCAGTTAATTTATAAAGAGGCGATTTTTGTGTGCCATTCACACTGGTCTTTTTCACATTGT
TTTGAGCTTATTGCAGTATATGTTTTGGGATTTTTCTGTAAAATGGGTGTAATTTTCCTAATACAGGTATGTAACAACAAAAGAAGTTGC
CTGCATGCCGGTCCAAATTGTTCTGTATAAAGATGCTCTTAAAAGACACAAGAGTTATCCTAGAACCTTAATTCTTTTTTATTTGAAATT
TTAAGTCAAGTCCTTTATAAAGACCATAGCAGTGGAAAACAGTGTACTTTTTAAAAAATTGCTGAATATAAAATCTTTGAAAATTTTCTT
TATGTGTGAAGACACAAAGTATGGGGGAAGACAGCAATCAAAACTAACTTTTTGTAGATAGCCATTTCATTTCTTTAAACTGTTTCAACG
CCAATATGTATTCTACAAAAGAGAATGGTTTTAGGCTCCAGTGTTATACTTTTTTTTATATATATATATAAAAATAAACTTTACGTAGTG
AAATCTTCCAAGTCTTTTCTGGAATTATTATAAATACTTTAGTTTTATTTTCTCATCTTAATCTCTCCATAATTTCCCATTTAAAGGTTT
ACAAATATGAGTGTGTGGATGCTTTAATTCATTTAACCTCACTCCTCAAAGGTAACATGCAACTTAGTTCTGTTATATGAGAGTCTTTTT
CTTTAATGTACTGGAAAAAGCCTATGTGAATCTGTTGATAGAATTTAAAATTCCAGGCCGGGCGTGGTGGCTCACGACTGTAATCCCAGA
ACTTTGGGAGGCCAAGGCAGGTGGATCACTTGAGGTCAGGAGTTCGAGACTAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAA
TACAACAGCCAGGTGTGATGGTGCACGCTCGTAATCCCGGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGAAGGCAGAGG
TTGCAGTGAGCTGAGATTGTGCCACTGCACGCCAGCCTGGGCAAGAGAGTAAGACTCTCTCTCAAAAAAAAAAAAAAAGAATTTAAAATC
CCAATTTATTTTCTAACTCTTTTATTGGATGTATTTAGAACACAGTATACCTATAGTATACCTATGTGTTTATTATGTTTGTAAATGGTA
ACTGACATTTAATTATTAGAAGTACTTACCCCTGCCTTCCTCCATTTTTATTCATGGCTACTTGAGAAAGCAAAAGGAAAAAATAATAGT
TATCAGTAGTGTCACTGGAAAGAAGAGAGGAGGGACAAAACTGAGCAGCAGAATTCGTATAGACATTTACGTTTAAATTCTAAAAGCCCA
ATTGAGATGTTCAGGGAGGGTTTGTTTTGCCCTTTGGCCTCATGAATGGGTTTCATGAATGGGCTTCAGTGGCTTATAAACTCTGTAAAA
TTCTATTCTAAATTTTGTACATTTATTTTGTTCCGGTTAATTCCAGAAGACATTTCAAACATTTTTCTTACACCATATAATAAAAATACT
TAACTAAATTGACAGTTATAAAAATAAATCAGTGAAATGTACCTTATACTTTAATAAAAAATGTTTTCAGAAATAGATAAGTGAAAGCTG
AGTGTTTCTTTGATAGGTTCCCCTGTACTATAGGAGTGATAATTGCAGCTATTGCAATAGTAGTAATTGTTAAATGGATACTAATGAATA
GCATAGCATAGTGGGTAAGAGTTTATATAGCACAGGCTCTAGAATCAGATTAAGTAGGTTCAAATACCAGTTCTGCCAGTAACTGGTTTT
AGAACCTTGGGCAAGTTAAAGAATGTCTCCCAGCCTCAGTTTCCCTATTTGTAAAATGGAAATAATGGTAGCTACCTCAAACCTCATTAC
GAATTCAATGAGTTAAACTTGAAAAGACTTATTACAGTAGCTGGCACATAAAGACTTGATAGTAGTTTATATGGATGCTATCTCATATTA
GCATATATGGAATTAATAGTGTATCACTATACTTTTTTTTTCTTTTTTTTTTTTGAATAGAGATCAGTCTATCACCCAGGCTGGAGTGCA
GTGGTGACATCATAGCTCACTGTAACTTCTCCCATACTCTACCAATCCTCCTGCCTCAGCATCCAGACTAGCTGTGATTACAGGTGTGCA
CCACCACACCCAGCTACATTTTTTTTTGGTAGAGACAGGGTCTCACTATGTTACCCAGTCTGGTCTCAAACTCCCGGCCTCAAGCAATCC
TCCCACTGGCCTCACAATGTTGGGATTACAGGTATAAGCCACTGCACACGGCCTTACTATGCTATCAATTCCATATATGGAAAGGTGTTT
TCCCTTTCAGAGCTCTTTAAAGCTCTGCAGAAGATTTACATGTGTTTATAGAGCTAAGAGAAATCAGGGCATGGAAATTGAGTGTGTAAT
AAAAATTAAACTCTTCATGTTATATAATCATGCATAACTTCTATCTTCATTCTCTGAAGTTGCCTAGAGCACCATCACAGCTAGGAAGCT
TCCATCATGAATTACCTTATTTCCAAAAGCAAGTACTCAAATAATTGTCTCAAGAGAGGAAGGACAAAACTGTTACAAGCTGAAATATTT
GGGGATTTGTTTGACTTGACTAGGGAACCACAAGTTTTCATATAATGCCTGATTTAGCCCTGTGCCTAACAGTTTAAATCTTAATGCTAA
TGTTAATTGCTTCCCAGTTGGTTGACCTTATAAGAAAACACTGTGTGGTATTTTAATGTGGTAAACATGTGAATGAAGGCCTGTGGCTCA
GTTAATCACTCCCACAACTTTGAGCTGTGAGTTTTACTGGTGGAAGGAACTTTAACAGGTCTTCGCTCTTGTCATTAGATATCAAAGAAC
TGAAATTAGTTGGAATTGTAAGCAGTGAATAGATGTGTTGTTAGAATGATTCCATCACTTATACATTGTTTAAAATGCTAATAAAGTAAC

>52427_52427_16_MDM2-XPOT_MDM2_chr12_69222711_ENST00000462284_XPOT_chr12_64838855_ENST00000332707_length(amino acids)=267AA_BP=240
MRDPRLQARKPRMVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTKRLYDEKQQ
HIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for MDM2-XPOT


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811150_230228.0498.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811150_230228.0498.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811150_230228.0498.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811150_230228.0498.0PYHIN1 and necessary for interaction with RFFL and RNF34


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69170_306167.0437.0MTBP
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15170_3060.0322.0MTBP
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13170_3060.0266.0MTBP
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16170_3060322.0MTBP
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14170_3060.0297.0MTBP
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13170_3060219.0MTBP
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12170_3060.0219.0MTBP
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14170_3060271.0MTBP
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811170_306228.0498.0MTBP
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15170_3060297.0MTBP
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69170_306167.0437.0MTBP
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15170_3060.0322.0MTBP
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13170_3060.0266.0MTBP
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16170_3060322.0MTBP
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14170_3060.0297.0MTBP
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13170_3060219.0MTBP
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12170_3060.0219.0MTBP
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14170_3060271.0MTBP
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811170_306228.0498.0MTBP
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15170_3060297.0MTBP
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69170_306167.0437.0MTBP
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15170_3060.0322.0MTBP
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13170_3060.0266.0MTBP
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16170_3060322.0MTBP
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14170_3060.0297.0MTBP
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13170_3060219.0MTBP
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12170_3060.0219.0MTBP
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14170_3060271.0MTBP
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811170_306228.0498.0MTBP
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15170_3060297.0MTBP
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69170_306167.0437.0MTBP
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15170_3060.0322.0MTBP
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13170_3060.0266.0MTBP
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16170_3060322.0MTBP
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14170_3060.0297.0MTBP
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13170_3060219.0MTBP
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12170_3060.0219.0MTBP
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14170_3060271.0MTBP
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811170_306228.0498.0MTBP
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15170_3060297.0MTBP
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69150_230167.0437.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15150_2300.0322.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13150_2300.0266.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16150_2300322.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14150_2300.0297.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13150_2300219.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12150_2300.0219.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14150_2300271.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15150_2300297.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69150_230167.0437.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15150_2300.0322.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13150_2300.0266.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16150_2300322.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14150_2300.0297.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13150_2300219.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12150_2300.0219.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14150_2300271.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15150_2300297.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69150_230167.0437.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15150_2300.0322.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13150_2300.0266.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16150_2300322.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14150_2300.0297.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13150_2300219.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12150_2300.0219.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14150_2300271.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15150_2300297.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69150_230167.0437.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15150_2300.0322.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13150_2300.0266.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16150_2300322.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14150_2300.0297.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13150_2300219.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12150_2300.0219.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14150_2300271.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15150_2300297.0PYHIN1 and necessary for interaction with RFFL and RNF34
HgeneMDM2chr12:69222710chr12:64833023ENST00000258149+69223_232167.0437.0USP7
HgeneMDM2chr12:69222710chr12:64833023ENST00000299252+15223_2320.0322.0USP7
HgeneMDM2chr12:69222710chr12:64833023ENST00000348801+13223_2320.0266.0USP7
HgeneMDM2chr12:69222710chr12:64833023ENST00000356290+16223_2320322.0USP7
HgeneMDM2chr12:69222710chr12:64833023ENST00000360430+14223_2320.0297.0USP7
HgeneMDM2chr12:69222710chr12:64833023ENST00000393412+13223_2320219.0USP7
HgeneMDM2chr12:69222710chr12:64833023ENST00000393413+12223_2320.0219.0USP7
HgeneMDM2chr12:69222710chr12:64833023ENST00000428863+14223_2320271.0USP7
HgeneMDM2chr12:69222710chr12:64833023ENST00000462284+811223_232228.0498.0USP7
HgeneMDM2chr12:69222710chr12:64833023ENST00000540827+15223_2320297.0USP7
HgeneMDM2chr12:69222711chr12:64833023ENST00000258149+69223_232167.0437.0USP7
HgeneMDM2chr12:69222711chr12:64833023ENST00000299252+15223_2320.0322.0USP7
HgeneMDM2chr12:69222711chr12:64833023ENST00000348801+13223_2320.0266.0USP7
HgeneMDM2chr12:69222711chr12:64833023ENST00000356290+16223_2320322.0USP7
HgeneMDM2chr12:69222711chr12:64833023ENST00000360430+14223_2320.0297.0USP7
HgeneMDM2chr12:69222711chr12:64833023ENST00000393412+13223_2320219.0USP7
HgeneMDM2chr12:69222711chr12:64833023ENST00000393413+12223_2320.0219.0USP7
HgeneMDM2chr12:69222711chr12:64833023ENST00000428863+14223_2320271.0USP7
HgeneMDM2chr12:69222711chr12:64833023ENST00000462284+811223_232228.0498.0USP7
HgeneMDM2chr12:69222711chr12:64833023ENST00000540827+15223_2320297.0USP7
HgeneMDM2chr12:69222711chr12:64833024ENST00000258149+69223_232167.0437.0USP7
HgeneMDM2chr12:69222711chr12:64833024ENST00000299252+15223_2320.0322.0USP7
HgeneMDM2chr12:69222711chr12:64833024ENST00000348801+13223_2320.0266.0USP7
HgeneMDM2chr12:69222711chr12:64833024ENST00000356290+16223_2320322.0USP7
HgeneMDM2chr12:69222711chr12:64833024ENST00000360430+14223_2320.0297.0USP7
HgeneMDM2chr12:69222711chr12:64833024ENST00000393412+13223_2320219.0USP7
HgeneMDM2chr12:69222711chr12:64833024ENST00000393413+12223_2320.0219.0USP7
HgeneMDM2chr12:69222711chr12:64833024ENST00000428863+14223_2320271.0USP7
HgeneMDM2chr12:69222711chr12:64833024ENST00000462284+811223_232228.0498.0USP7
HgeneMDM2chr12:69222711chr12:64833024ENST00000540827+15223_2320297.0USP7
HgeneMDM2chr12:69222711chr12:64838855ENST00000258149+69223_232167.0437.0USP7
HgeneMDM2chr12:69222711chr12:64838855ENST00000299252+15223_2320.0322.0USP7
HgeneMDM2chr12:69222711chr12:64838855ENST00000348801+13223_2320.0266.0USP7
HgeneMDM2chr12:69222711chr12:64838855ENST00000356290+16223_2320322.0USP7
HgeneMDM2chr12:69222711chr12:64838855ENST00000360430+14223_2320.0297.0USP7
HgeneMDM2chr12:69222711chr12:64838855ENST00000393412+13223_2320219.0USP7
HgeneMDM2chr12:69222711chr12:64838855ENST00000393413+12223_2320.0219.0USP7
HgeneMDM2chr12:69222711chr12:64838855ENST00000428863+14223_2320271.0USP7
HgeneMDM2chr12:69222711chr12:64838855ENST00000462284+811223_232228.0498.0USP7
HgeneMDM2chr12:69222711chr12:64838855ENST00000540827+15223_2320297.0USP7


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MDM2-XPOT


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MDM2-XPOT


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource