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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MECOM-LPP (FusionGDB2 ID:52502)

Fusion Gene Summary for MECOM-LPP

check button Fusion gene summary
Fusion gene informationFusion gene name: MECOM-LPP
Fusion gene ID: 52502
HgeneTgene
Gene symbol

MECOM

LPP

Gene ID

2122

4026

Gene nameMDS1 and EVI1 complex locusLIM domain containing preferred translocation partner in lipoma
SynonymsAML1-EVI-1|EVI1|KMT8E|MDS1|MDS1-EVI1|PRDM3|RUSAT2-
Cytomap

3q26.2

3q27.3-q28

Type of geneprotein-codingprotein-coding
Descriptionhistone-lysine N-methyltransferase MECOMAML1-EVI-1 fusion proteinMDS1 and EVI1 complex locus protein EVI1MDS1 and EVI1 complex locus protein MDS1PR domain 3ecotropic virus integration site 1 protein homologmyelodysplasia syndrome-associated protein lipoma-preferred partnerLIM proteinlipoma preferred partner
Modification date2020031320200313
UniProtAcc

Q03112

Q93052

Ensembl transtripts involved in fusion geneENST00000494292, ENST00000485957, 
ENST00000264674, ENST00000392736, 
ENST00000433243, ENST00000460814, 
ENST00000464456, ENST00000468789, 
ENST00000472280, 		ENST00000471917, 
ENST00000312675, ENST00000448637, 
ENST00000543006, 
Fusion gene scores* DoF score33 X 21 X 11=762325 X 27 X 9=6075
# samples 4334
** MAII scorelog2(43/7623*10)=-4.14795031118505
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(34/6075*10)=-4.1592777572428
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MECOM [Title/Abstract] AND LPP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMECOM(169381124)-LPP(188242453), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMECOM

GO:0045892

negative regulation of transcription, DNA-templated

10856240|11568182

HgeneMECOM

GO:0045893

positive regulation of transcription, DNA-templated

11568182|19767769

HgeneMECOM

GO:0051726

regulation of cell cycle

11568182


check buttonFusion gene breakpoints across MECOM (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LPP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-A4GN-01AMECOMchr3

169381124

-LPPchr3

188242453

+


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Fusion Gene ORF analysis for MECOM-LPP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000494292ENST00000471917MECOMchr3

169381124

-LPPchr3

188242453

+
5UTR-3CDSENST00000485957ENST00000312675MECOMchr3

169381124

-LPPchr3

188242453

+
5UTR-3CDSENST00000485957ENST00000448637MECOMchr3

169381124

-LPPchr3

188242453

+
5UTR-3CDSENST00000485957ENST00000543006MECOMchr3

169381124

-LPPchr3

188242453

+
5UTR-intronENST00000485957ENST00000471917MECOMchr3

169381124

-LPPchr3

188242453

+
In-frameENST00000494292ENST00000312675MECOMchr3

169381124

-LPPchr3

188242453

+
In-frameENST00000494292ENST00000448637MECOMchr3

169381124

-LPPchr3

188242453

+
In-frameENST00000494292ENST00000543006MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000264674ENST00000312675MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000264674ENST00000448637MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000264674ENST00000543006MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000392736ENST00000312675MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000392736ENST00000448637MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000392736ENST00000543006MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000433243ENST00000312675MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000433243ENST00000448637MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000433243ENST00000543006MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000460814ENST00000312675MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000460814ENST00000448637MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000460814ENST00000543006MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000464456ENST00000312675MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000464456ENST00000448637MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000464456ENST00000543006MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000468789ENST00000312675MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000468789ENST00000448637MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000468789ENST00000543006MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000472280ENST00000312675MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000472280ENST00000448637MECOMchr3

169381124

-LPPchr3

188242453

+
intron-3CDSENST00000472280ENST00000543006MECOMchr3

169381124

-LPPchr3

188242453

+
intron-intronENST00000264674ENST00000471917MECOMchr3

169381124

-LPPchr3

188242453

+
intron-intronENST00000392736ENST00000471917MECOMchr3

169381124

-LPPchr3

188242453

+
intron-intronENST00000433243ENST00000471917MECOMchr3

169381124

-LPPchr3

188242453

+
intron-intronENST00000460814ENST00000471917MECOMchr3

169381124

-LPPchr3

188242453

+
intron-intronENST00000464456ENST00000471917MECOMchr3

169381124

-LPPchr3

188242453

+
intron-intronENST00000468789ENST00000471917MECOMchr3

169381124

-LPPchr3

188242453

+
intron-intronENST00000472280ENST00000471917MECOMchr3

169381124

-LPPchr3

188242453

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000494292MECOMchr3169381124-ENST00000448637LPPchr3188242453+55181351771115312
ENST00000494292MECOMchr3169381124-ENST00000312675LPPchr3188242453+178611351771667496
ENST00000494292MECOMchr3169381124-ENST00000543006LPPchr3188242453+178611351771667496

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000494292ENST00000448637MECOMchr3169381124-LPPchr3188242453+0.0013658930.99863404
ENST00000494292ENST00000312675MECOMchr3169381124-LPPchr3188242453+0.0002754720.99972457
ENST00000494292ENST00000543006MECOMchr3169381124-LPPchr3188242453+0.0002754720.99972457

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Fusion Genomic Features for MECOM-LPP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for MECOM-LPP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:169381124/chr3:188242453)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MECOM

Q03112

LPP

Q93052

FUNCTION: [Isoform 1]: Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis. {ECO:0000269|PubMed:10856240, ECO:0000269|PubMed:11568182, ECO:0000269|PubMed:15897867, ECO:0000269|PubMed:16462766, ECO:0000269|PubMed:19767769, ECO:0000269|PubMed:9665135}.; FUNCTION: [Isoform 7]: Displays histone methyltransferase activity and monomethylates 'Lys-9' of histone H3 (H3K9me1) in vitro. Probably catalyzes the monomethylation of free histone H3 in the cytoplasm which is then transported to the nucleus and incorporated into nucleosomes where SUV39H methyltransferases use it as a substrate to catalyze histone H3 'Lys-9' trimethylation. Likely to be one of the primary histone methyltransferases along with PRDM16 that direct cytoplasmic H3K9me1 methylation. {ECO:0000250|UniProtKB:P14404}.FUNCTION: May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus. {ECO:0000269|PubMed:10637295}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLPPchr3:169381124chr3:188242453ENST00000312675311414_473102613.0DomainLIM zinc-binding 1
TgeneLPPchr3:169381124chr3:188242453ENST00000312675311474_534102613.0DomainLIM zinc-binding 2
TgeneLPPchr3:169381124chr3:188242453ENST00000312675311535_603102613.0DomainLIM zinc-binding 3
TgeneLPPchr3:169381124chr3:188242453ENST00000543006311414_473102613.0DomainLIM zinc-binding 1
TgeneLPPchr3:169381124chr3:188242453ENST00000543006311474_534102613.0DomainLIM zinc-binding 2
TgeneLPPchr3:169381124chr3:188242453ENST00000543006311535_603102613.0DomainLIM zinc-binding 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-1171065_111601117.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-1161065_111601052.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-1171065_111601053.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-1151065_111601043.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-1161065_111601052.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-1161065_111601053.0Compositional biasNote=Asp/Glu-rich (acidic)
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-11778_19001117.0DomainSET
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-11678_19001052.0DomainSET
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-11778_19001053.0DomainSET
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-11578_19001043.0DomainSET
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-11678_19001052.0DomainSET
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-11678_19001053.0DomainSET
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117609_62201117.0MotifNuclear localization signal
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117741_74501117.0MotifCTBP-binding motif 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117772_77601117.0MotifCTBP-binding motif 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116609_62201052.0MotifNuclear localization signal
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116741_74501052.0MotifCTBP-binding motif 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116772_77601052.0MotifCTBP-binding motif 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117609_62201053.0MotifNuclear localization signal
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117741_74501053.0MotifCTBP-binding motif 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117772_77601053.0MotifCTBP-binding motif 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115609_62201043.0MotifNuclear localization signal
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115741_74501043.0MotifCTBP-binding motif 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115772_77601043.0MotifCTBP-binding motif 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116609_62201052.0MotifNuclear localization signal
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116741_74501052.0MotifCTBP-binding motif 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116772_77601052.0MotifCTBP-binding motif 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116609_62201053.0MotifNuclear localization signal
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116741_74501053.0MotifCTBP-binding motif 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116772_77601053.0MotifCTBP-binding motif 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117209_23601117.0Zinc fingerC2H2-type 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117263_28501117.0Zinc fingerC2H2-type 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117291_31301117.0Zinc fingerC2H2-type 3
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117319_34201117.0Zinc fingerC2H2-type 4
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117348_37001117.0Zinc fingerC2H2-type 5
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117376_39801117.0Zinc fingerC2H2-type 6
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117405_42701117.0Zinc fingerC2H2-type 7%3B atypical
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117912_93401117.0Zinc fingerC2H2-type 8
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117940_96301117.0Zinc fingerC2H2-type 9
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117969_99101117.0Zinc fingerC2H2-type 10
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116209_23601052.0Zinc fingerC2H2-type 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116263_28501052.0Zinc fingerC2H2-type 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116291_31301052.0Zinc fingerC2H2-type 3
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116319_34201052.0Zinc fingerC2H2-type 4
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116348_37001052.0Zinc fingerC2H2-type 5
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116376_39801052.0Zinc fingerC2H2-type 6
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116405_42701052.0Zinc fingerC2H2-type 7%3B atypical
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116912_93401052.0Zinc fingerC2H2-type 8
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116940_96301052.0Zinc fingerC2H2-type 9
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116969_99101052.0Zinc fingerC2H2-type 10
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117209_23601053.0Zinc fingerC2H2-type 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117263_28501053.0Zinc fingerC2H2-type 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117291_31301053.0Zinc fingerC2H2-type 3
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117319_34201053.0Zinc fingerC2H2-type 4
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117348_37001053.0Zinc fingerC2H2-type 5
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117376_39801053.0Zinc fingerC2H2-type 6
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117405_42701053.0Zinc fingerC2H2-type 7%3B atypical
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117912_93401053.0Zinc fingerC2H2-type 8
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117940_96301053.0Zinc fingerC2H2-type 9
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117969_99101053.0Zinc fingerC2H2-type 10
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115209_23601043.0Zinc fingerC2H2-type 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115263_28501043.0Zinc fingerC2H2-type 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115291_31301043.0Zinc fingerC2H2-type 3
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115319_34201043.0Zinc fingerC2H2-type 4
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115348_37001043.0Zinc fingerC2H2-type 5
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115376_39801043.0Zinc fingerC2H2-type 6
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115405_42701043.0Zinc fingerC2H2-type 7%3B atypical
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115912_93401043.0Zinc fingerC2H2-type 8
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115940_96301043.0Zinc fingerC2H2-type 9
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115969_99101043.0Zinc fingerC2H2-type 10
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116209_23601052.0Zinc fingerC2H2-type 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116263_28501052.0Zinc fingerC2H2-type 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116291_31301052.0Zinc fingerC2H2-type 3
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116319_34201052.0Zinc fingerC2H2-type 4
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116348_37001052.0Zinc fingerC2H2-type 5
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116376_39801052.0Zinc fingerC2H2-type 6
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116405_42701052.0Zinc fingerC2H2-type 7%3B atypical
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116912_93401052.0Zinc fingerC2H2-type 8
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116940_96301052.0Zinc fingerC2H2-type 9
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116969_99101052.0Zinc fingerC2H2-type 10
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116209_23601053.0Zinc fingerC2H2-type 1
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116263_28501053.0Zinc fingerC2H2-type 2
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116291_31301053.0Zinc fingerC2H2-type 3
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116319_34201053.0Zinc fingerC2H2-type 4
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116348_37001053.0Zinc fingerC2H2-type 5
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116376_39801053.0Zinc fingerC2H2-type 6
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116405_42701053.0Zinc fingerC2H2-type 7%3B atypical
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116912_93401053.0Zinc fingerC2H2-type 8
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116940_96301053.0Zinc fingerC2H2-type 9
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116969_99101053.0Zinc fingerC2H2-type 10
TgeneLPPchr3:169381124chr3:188242453ENST0000031267531141_370102613.0Compositional biasNote=Pro-rich
TgeneLPPchr3:169381124chr3:188242453ENST0000054300631141_370102613.0Compositional biasNote=Pro-rich


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Fusion Gene Sequence for MECOM-LPP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>52502_52502_1_MECOM-LPP_MECOM_chr3_169381124_ENST00000494292_LPP_chr3_188242453_ENST00000312675_length(transcript)=17861nt_BP=135nt
AGAGAGAGGGAGGGAGCGAGAGGGAGAGCAAAAGAAGGAAAGGATCCAAGAAAAAAAAGCCCCAACCACACACCAGCGGCTGCAGGACTG
GGCACAGCATGAGATCCAAAGGCAGGGCAAGGAAACTGGCCACAAGGGAATCCCGGAGGCAAGACACTTGAGGAGAGGCGCTCCAGCCTG
GACGCTGAGATTGACTCCTTGACCAGCATCTTGGCTGACCTTGAGTGCAGCTCCCCCTATAAGCCTCGGCCTCCACAGAGCTCCACTGGT
TCAACAGCCTCTCCTCCAGTTTCGACCCCAGTCACAGGACACAAGAGAATGGTCATCCCGAACCAACCCCCTCTAACAGCAACCAAGAAG
TCTACATTGAAACCACAGCCTGCACCCCAGGCTGGACCCATCCCTGTGGCTCCAATCGGAACACTCAAACCCCAGCCTCAGCCAGTCCCA
GCCTCCTACACCACGGCCTCCACTTCTTCAAGGCCTACCTTTAATGTGCAGGTGAAGTCAGCCCAGCCCAGCCCTCATTATATGGCTGCC
CCTTCATCAGGACAAATTTATGGCTCAGGGCCCCAGGGCTATAACACTCAGCCAGTTCCTGTCTCTGGGCAGTGTCCACCTCCTTCAACA
CGGGGAGGCATGGATTATGCCTACATTCCACCACCAGGACTTCAGCCGGAGCCTGGGTATGGGTATGCCCCCAACCAGGGACGCTATTAT
GAAGGCTACTATGCAGCAGGGCCAGGCTATGGGGGCAGAAATGACTCTGACCCTACCTATGGTCAACAAGGTCACCCAAATACCTGGAAA
CGGGAACCAGGGTACACTCCTCCTGGAGCAGGGAACCAGAACCCTCCTGGGATGTATCCAGTCACTGGTCCCAAGAAGACCTATATCACA
GATCCTGTTTCAGCCCCCTGTGCGCCACCATTGCAGCCAAAGGGTGGCCATTCAGGGCAACTGGGGCCTTCGTCAGTTGCCCCTTCATTC
CGCCCAGAGGATGAGCTTGAGCACCTGACCAAAAAGATGCTGTATGACATGGAAAATCCACCTGCTGACGAATACTTTGGCCGCTGTGCT
CGCTGTGGAGAAAACGTAGTTGGGGAAGGTACAGGATGCACTGCCATGGATCAGGTCTTCCACGTGGATTGTTTTACCTGCATCATCTGC
AACAACAAGCTCCGAGGGCAGCCATTCTATGCTGTGGAAAAGAAAGCATACTGCGAGCCCTGCTACATTAATACTCTGGAGCAGTGCAAT
GTGTGTTCCAAGCCCATCATGGAGCGGATTCTCCGAGCCACCGGGAAGGCCTATCATCCTCACTGTTTCACCTGCGTGATGTGCCACCGC
AGCCTGGATGGGATCCCATTCACTGTGGATGCTGGCGGGCTCATTCACTGCATTGAGGACTTCCACAAGAAATTTGCCCCGCGATGTTCT
GTGTGCAAGGAGCCTATTATGCCAGCCCCGGGCCAGGAGGAGACTGTCCGTATTGTGGCTTTGGATCGAGATTTCCATGTTCACTGCTAC
CGATGCGAGGATTGCGGTGGTCTCCTGTCTGAAGGAGATAACCAAGGCTGCTACCCCTTGGATGGGCACATCCTCTGCAAGACCTGCAAC
TCTGCCCGCATCAGGGTGTTGACCGCCAAGGCGAGCACTGACCTTTAGATTCAGTCACCTGTTCAGCCGGCACTGAGAAGAACGAACACA
AGAAAAAGATAAGAAATACTAGAGTAAAGGCCATCAAACTACGCGATAGTCTCTGTTCTTCATCTGCTATTAACCTTGCCTTAGAAACAC
ATAAATTATGAGATTTTTTTTAAAAGTTGTTACCAAATACACATTTCACATTGAATCATGTAGGATCTTGATGGGCCTTTGTTCCCAAGG
ACTTCCACATTTTTGCACAGATTATGCTCCATCCCATTCACTTCTGCATTCCTGTAACTTTTAATCCCTATGTTTGTCTCACTTTTCATC
TGGTTGAATGGCTTTTCTTAGTGTGGTATTTGCTGTCACATAGTTTTTCCTGGGTGAGTCTGCCAACTCACAGGTGCTTTTAGGCTTGAA
ATCTCCATCCTATCATTTCCGTTTTGCCTGTGACTGTAAAGAGTAGCCATTCTTTTCCCATGTATTGAAGAGGATATTCTTCTCTTGCTT
TATACTACTCACGTCCTTGGGGAGGGAAATGCACAATTTTTTTTTGTTAGGCTGTAAAGAATTTAAGCTGTAAATTACATAAGTTAGAAC
AAGCCCAAATTTAATTTGCAACCATCAGAATTCAGAATCTATAGTGACCAGTGATCAAGGCTAATTGGAAAAGAGTTATCGGCCCATAGC
TAATAAGTAGTGACAGACAACCAAGCTTCAATATTTTTCTAAAGAAATTACAGGTGGGATATGCTAGAAAAGGCATTTTGGGGTTATGTT
TAAAAAAACATTATTGTCCCACAATATTACCTTAAGATTTTTCTTTTCCGCACTACCTGAACATTGTAATACAGACAAACTTGATTTCTT
CTAGAAGATAACATTTTCAATACTGTCCCACTTCTCATCTTAAAAATATTGTCATGTTTATTCTAATATCCAACACAACTATCAAAATTG
CCTTTTTCTCTAGAGGATGAAGGCTGTGAAAAAACCGTTCAAATTCTCTTCTTTTTCTTTTTTATTACCAGGTCCATTTTGCCTGACAAT
TGCAAATCAGAGCATACAAAATAAAACTGTGCAGTTTTGTTTGGTTTACTTTCAAAAGAGTAGAAAGCTTGAAAAGATTCTGAAACCACA
GTTTCATTATTCTCATAATCCTTCTGCAACTGAAATTACATATTGCAGGAGACATTTTCATATCATCAATGTGACATTTACACCACACTT
TCAAAGACAATCACTGAAACAAAAATTGTCTTTATGAGCTAAAAATATGCAGAATCTCTGCCTAGAATCTTTATTCAAACTTTTATTAGC
CAGTGAAACACTTGCTTGCCAACTGCCAAGCCATACTTATTAAGTTCGAACATGTTTCACTTAAGGAGAGACACCTAGCTTAGTCATGGC
AAGTTGCCATTTTGTAAACTAAGGATTTTGGACTGAGATTTCTTAAATCTTTCTTCAAATCTCCCACAAGTATATACTTTTAAATTATGG
AGTATTTTAAGTCTACAAAAAGGTATAAATAATAATATAATGAATTCCTATATACCTAATACCCAGTTTAAGACACCAAATATAACAAGT
ATAATTACATCCTCCAATGTACCGTTTCCTTATTCCACAGATATCTTTTTCATTATTGTGAAGTGATGTTCAGATTTCTAGTTTTTTTTC
TAGTTTTTAATTTTAACATCAGAACTGAAATAAAAAATTATGGATACGTGTTTTGAATTGCAAACTATTCCTCAGGAATTCCAATTAAAT
TTATTTTACTTGAATAGGAATGATCATAAAAGTGATTCTTTTTTTGTGACTAGAAATTCTTAAGCCGATGGTCACTATAGCTCATCCTTA
ATGTATGGCTCATTTGCTTTTGTCACTAAACGGTTTTGTGTTAGAACCACCAAAATTATAGCTTTTAAGAGCTTCCTTTGACCACTGTCT
TTTTCTTACCCTAGTTCTCTTATCTTTGATCGTATATTTCTCATAATGTGAAATATGATGAGATTCACTTAGGGGCAGCATGTTAGTTTT
GGGAGGCAATGTCAACTGTGTCTCTGAATTCCTGTCTTCCAAATTGAAGCCAGACCATGCTGATGACCTCAAGTAGCACTGACTATTTGA
CAATAGGGCTGATAATGTAATCGGCTTGAATTTTGACTTAGTAACTTTTTATGTAATACTTTCGGAGAAATTCTCTTTAGGACAAAGCAG
AGAGTCCAATTTATTGAGGGATAGATTGTATCTCTTAAAGTGGTCATATTATTATTAATTTTGCCAAAAGAAGAAGAATTTATTGAATAT
TTATACTATAAAATGCAGTAACATTCTACTTGCTTATTACATTTAAATCCTTGTGTAACTGAATGTTTACATGTCAAGAGGAAAAGCTGT
AAGAAAATGCTGTCACAGACCCATCCCTGTGGCATCGTCAGCAGAATACTGCTTGCTTACAATCTTTATTATGCATTCTTATAACATAAC
CTCAGAGTATCTTTACCAAAGGTTTTTAAAGTAAATCTCTTTTTAAGATAGACTTATTCTTTTATAATAATGAATGTGCACTCATACATA
TGTAGAAACATTTAGATTTAGAGTTTTTTTTTTCTTTCACAAGGTATAATAAGGAAAGGATCCTACAATATTTTATTCTAGGGTTTCTTA
AATATATGATTTATATTACTGTCTTTTCTATTAATCATTTGATTTAAACAATGCCAAGTCACTCTTTTTTAGTTGCATGAAATTTTGCCT
GCAACAGAGAGAAAAAGATTGTATTACTTTAATGATTATAATCATACTGTCTGCTGATATAATATCATAATTGTTGTGGTTTAAATACAT
AAATAGTAGAAAAATCAGAGTCTATAACAGAAAGTTTGTAAAAATATACTGATTTTGAAAAGTATCAGGAATATAAATATTTGGTAATTC
TGTGTAACAAGAGAGACATGGAAAAGGAAAAAAATCCACTATATCATGGGCTCTGCAGAACATATCAAAATAGGATTTCTTAAATTTTTC
AACCCCCAGACCATACTGACTCAACATGGAGTCTCACTGGCCAAGAAAATTGCCTTTAAAACTCGAAAATAAGGCCAGGTGTGGTGACTC
ACACTTGTAATCCCAGCAATTTGGGAGGCTGAGACAGGAGGATTGCCTGAGGCCAGGAGTTTGACACCAGCCTGGGCAACATAGTGAGAC
CTTGTCTCTACAAAAAATAAAATAAAATAAAAACCAAATTAGCCAGACATGGTGGCATGCGCTTGTTTAAAAAAACAAATAAATAAATAA
TCGACTCAAAAATAAGTCATGTGTCCCAGCATAAGGCATCAGGTTGTTAGATGCTGGCATCTCTGCAGCTCAAAGATGTGGGTTCTTTTT
CTTGTCATTAACACATTGTTATTTCTGTAGGAGCAACTTCTCTGATCAAAATTACTTTTCTGGGTATGTGCTGATTAAGGGGGTGGACTT
ATCAACACTATAATTGTTCCCTATGAAAGATTCCACAGAGATGTTTATGGTGAGGTTTAAAGGATATGAAACTCTACATTTAAACAAGTA
TTTTATATTTGGGTACAGAGGAAGAAAGAGAGGGCTTTTTCCATGGGGCTATAGTAGAGAGTTAGTGGAATATAGACAGGACTCTGAAAA
CACAACTTCCAGCCATTTTTTTAGTTAGTAAAAATCCTATTAATGTGAACCAGCCAGGAATAACAGTGTTATTTCTATTGGATATGGTTT
GGGCTTCTCTTGTCAAATCTGTGTCGGCTGCCCCCTGATCCTTCCATTATCAAGTTTTGAAGGGTGTTGGGGAAATTATGGCAGCTGCTA
GGGAGATCAGGGAAACACTGATGTAACCTCAAAGCCTCTCACCATTCCTCTTGGCTTGGAAAGGCTTTATTTTTTCATATACATTTCTAG
AAATATTGCTATTCTACCTTAGTATTTCACATTTGTAGTTCAAACAAGCGATTGTCCATCTGTTGCCTAGAGCTATAGTACATGTGTGTT
ATGAATGAAATATGACAGCATGTTCCATACCCCTGCTTTAGCCATCTGTGGGAAACCAGCAAACTGAAAAAGACACCTCTGCAAAATGTG
CCTCAAGTCCATTTCTTGGGATCGCTCGTTTGGTGCACTCTCGTGGGAGACAATCAGAGAACAACATATACTTGTGCCTTATTTTCAAAG
AATCTATTTACACTACTATGAATATTCCACTGAAGAGTCAATGATGTAAATGATAACCACCAAATCTCAAAAATATACTCACCAAAAAGT
AAAAAAGTAAAAAAAAAAAAAAAAGAAAGAAAGAAAAGAAAGAGAGAGAAGTCAACTTTTCATCTTAATATATTCTAGTAGTATTTATTT
TTTCCTTGTCTTGGAAGTATCTCATAGGTCTTTAAATGAGTAAAACATTTTTATGCCAGAAGGTGATATAATGGATGTTAGTGTTTTTTA
TTTGATTTTACAGTAGTTTTAGTCAGATAATGAGGACAGAGACTTCAACTTGATTCTTTACCACCATTCAGCATATTTTTTAATTGTCTT
CATTGTATTTGCTTAATAGTGGTCCAGACAAGTTCAAAACTTGTTCTCAGTGAGGCATTAATATGGTGCAACCATGAATATTTCAGGCCA
AGTTATTCACTTGACAGATAACTAGAATGAAACTTTTCTCATGAGGCTGTTGTTTGGTTAGCATAGCCTTATTTCAAACCTTAAAAAGTT
ACCTGACTGAAGCTACTATGACTTGGTAAGGATTCTTCCTCTCTTGCTTTCTTCCTCCCTTCCTTTCTTCCTCTTCCTTCCTCCTCTTCT
TATTTTCTTTCCTACTTTCCATCCTACCTATTAGTGTTGCTGTACTTGGATTTTTTGTAAATTAAATCAATGCATTATGATTTTAGGGAA
TTATGATTATATTCATAAGGGGAAGGCTACCAGAAAATATATGTGGCATCCATAAAATCTTCTTTTATAGGGGCATATTTTTTAGGTTGT
ATTTATTCGTAAAGTGAAATGAGATAATAGAGTCTTTCTGTTTCATGTTAATGAATTTTCATCAGGGACTGAGGTCATAGATTCTTGGAA
AATTCATTTGTGACTGATCTAGTTTTCTCAGCTGTATGCAAAGTAATCTTTCAAAGACTAGGTTAAGATTTTTTTTTTAAGTCTGAAGCA
ATGTAACCCCAAAAAATTATAATTTTAATGATGGCATTTTATTTTATTCCATTGCAGCTTGATAACTTTCCTTATAGCAAAGGAATAACT
ATTGTATTTTCAGAATTTTAACACAGATTAACACTTAGCCTGTAAGACTAATAATATATTGTAATAGTTGATACTAAAATATTTTTCAGC
AGGTTGGACAGCACCAGTTTTTCTTAGATCACAGACTACAGGCAGAATTTCCCTTCAATCCAGAAAAAAGGACACTAATTTCCTTTTCTA
TTTAATTTTCCTGGCCCTTGTGCAAAAAATTGTGGACTCTATCTTAGTTACAACATGCATGTCCCTTATTTTGTGGAGAGCTGTGTGAAA
GATGCGTTTTTTTTCTTTTTTTCTTTTTTTTTTTTTTGAGACGGAGTCTGGCTCTGTCACCCAGGCTGGAGTGCAATGGCACGATCTCCT
CTCACTGCAAGCTCCGCCTCCCAGGTTCACGCCATTCTCCTGTCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCTGCCACCACGCCC
GGCTAATTTTTTTGTATTTTTAGTAGAGATGGAGTTTCACAGTGTTAGCCAGGATGGCCTCGATCTCCTGACCTCGTGATCCACCCGCCT
CGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCCCGCGTGTTTTTTTCTTTAGCTGATTGACAGGTCCCCTTCAAAGTT
ACAAAAAAAAGTGCTAATTTTTGCTGTTAAATTCTGGTTGTTATTTAATTGACAGAAGTCTCTTGATGCACGAATAAATATCTCTACATC
TAGCCTTTGTTAAAAATAAAAATTAATATTCTACAAACACCTACATATACTAGAGAGGGGTGAAACACTGCAGCTAATTCCTTTATAATA
CTTTCAGATGATTGCATTAAGCCTTTCATGTTATGTGGCATTGTTAATTTTTCCTAGATACCCATCCACTTAAGGGCCAGAGAAATCCTT
ATTCATTTAACTCTGGTGGGCATTTATGTAACATACCCAAATAAAAACGTTATTAAACAGCCACAATCGCATTCAGTCAACTTGGCACTG
AATGTAGCTTCTAAAATCAGTTCTCTACCCTACGAATGGAATGTTCTACCAAGAAAGAGAAGCATCACCATGTCATCTTGTGTTCTACAC
CACTATAGAGAGTTACAGTTGCCCCCAAACACGAATGCTATTCCCAAATAAAATAGAATCATGCTTTGGGAGGCCAAGGCGGGCCGATCA
CGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAAAAAAAAAAAATACAAAAAATTAGCCTGGCT
CAGTGGCGGGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAAGCGGAGCTTTCAGTGAGCCGAG
ATAGCGCCACTGCAGTCCGGCCTGGGCGAAAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAATAGGATCATGGCCCTTTTAAAGA
TCTGAATCTTCTCTGTTATTTTCCTGATGAATCACCATCCCATATCTTCTTAGTCCTGGCCAGTATGTAGTTGCGCTCACATACGTCTAT
TCTAGCTCTGTAGCTCCACAAAACAAGTCTTAAGTCCAAATCTTTGCCTCTTCATGTCTGATATCACCAACTCATTCAGCTTTTCTTCAC
TTATTGACATAGTGTCATGTCCTATCACTCTCTGCTGCTTCTTTAAACAGTGGACACAAACATATTTTCTAATTTTCAGTGTACTCAGTG
AAACTTGGCAGTTCACCATGAGTCAGGCTAGGTTGAAAGGCTTTCTTTAGGGTTGAAAGTAAACGAAATTGGAATCACCCAAAGAGAATT
TCCCCAAAAAACCTCAGACCCAGAAGTGTAAAAGCTACAGAAGGATAGAACTCCCATGTCTACAGACAGTTCTGTTACTTTTTGTTCTGT
ACTATTTTGGATGTTGCCAAAATCAAATTCATCCTGAAAACAGGAAGCAAGCTAATGCATATGCCATCCATGAGATTCCCACTTCTGGGT
CAGTTCATATTCCATTCAACCTTTTCCTTTTATCCTTGTCTTCTTCAGAATAAGACATTTTTCCTCCATATTTTCATATTAAATATTAAC
ACTTTATAGGTTCTACTTTAATATATGGACACTTTACAGGTTATACATAAATATTTGCTGGTTGATTGATTTCGAGATTCATTCATTCTG
TGCTCAAATATTTGTACCTAGAGACGTTACATGTTAGAAAAAGTGAGCAGCTTCTTTCTCTAATCATTTAGGAGTCCATATTTTTCTTTT
CTTTTTGTTCTCCCAACATCCTTATCTCTTACTCAGCTCTTCAATTTATAATTACCAAATAATCACTGTTAGAGAATCAGCCCCTAAGTA
ACTTTGATTCTGGCCAACTGTAATAAGATCCAACCACTTAAATCTGTACTTACTCAATAGGAAGGAATGTGACATCAGGAAGAGTCATTC
CAGTGACATTAGTAAGACTTTATGGAGTACATAAAATTTGATAAGAAATCTTGAGCTGATTCTTTGACTTGATTTAGAAGTTGAGAAAAG
AGTATTTAAGGCACAACAGGGAAACATGGGCTATACTCAGAGAAGACCCTCTGCATTGGCCAAAATATCATGGATTCTGGAAATTCCTTC
TTAACAGAAAAAAAAGGCTTCCAAATAATCAGGCTGAATGGGAAGAAAAAGGCATAGAGGAAGCCTGAGGAAGTATTTACTTGCTTTTCC
CATCTCTTTATAATTGGAAGAGAAGATGATCTGCCAAAATATAACCCAGCATGCACAGTATGGACAGGAAGCAGCCCTCCATGAACTTTA
TTATCACAGAATATGAGCATTCTTATTGATCCACAGCTACATCTTCTATTCTTGCAGCAAGGGTACATGTCCTTTGACCCTCCACAAAAG
AACAAGCAGGACATCTCTATTTTCCTATTGAGTCTGAGTCCATTATTAGAAAGGACTTCCCAGCCATCTTTTCTACTTGGTATTAAAATT
CCCTTACAGATTCATTGCTAAGTGCCAATTCTTTTTTTTTCTTTTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGC
AATCTCGGCTCACTGCAAGCTCCGCTTCTCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGACGCCCGCCA
CCGCGCCCAGCTAATTTTTTTTGTACTTTTAGTAGAGACGGGGTTTCACCGTGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGG
CCTCCCAAAGTGCCAATTCTGACTCTACTTAAACATCACCTGTATCAGGGAGCTCATTATTCCTTGAGGTCTTACATTTCTTTCAGCACA
TTTTGTTCCAAGCTACACGACTTTAAAACAGAGCCAGCCTTTGGGGCATATGTTCTCTTTGGTGCCACACAAAACCTGTAGTACATGATA
CAGTGTTGCTTCCCCCCTCCTTTTCCTTCCATATATATTTGTTTTGTTTTGGGCATTGCATTACTTTTTTGAATTTTTAAGAATCTCTAA
AATTAGTCTGAAGGATGTTCTGAGGGCCAGACATTAGAATTTGTGAGTTTTTTTGTTGCTGGTTGTACTTTCCTATTTAGAAGACAGACC
GTTCTGACAGTTGTTGTGTAGCTTCATGCCTTCCCCAGTAACTAACCCATGAACAGTACACCCCTTTTATCTGACTTGTTGATAATGACC
TTAAAAATGTTAGGAAATGGGCCGGGCGCGGTGGCTCGTGCCTGTAATCCAGCACTTTGGGAGGCCGAGGCGAGCGGATCATGAGGTCAA
GAGATCGAGACCATCCTGGTCAACATGGTGAAACCCCGACTCTACTAAAAAAAATACAAAAATTAGCCGGGCGTGTTGGCGGGCGCCTGT
AGTCCCAACTACTTGGGAGGCTGAGGCAGGAGAATCACCTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTGCGCCACTGCACTC
CAGCCTGGGCGACAGAACGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAGGTTGGGAAATATTGGTGTATAATCCCCATGTCTAAC
AAGGAAGAAGTCAAAAGCAAAAGATAGTGGTATTGCCGAAAACTCATTATTTCTAGTTAGTTCATCTGTGGAAAAGGATATCGTTCTTGA
GGAGAGGGGTTCTATTATGCTATAGTTTTCTATGGAAATGTACAAATGCTTTCCTCATTGCTCTGGATGACTATTTAGTTTAAATAATAT
ACCTTTGTCATGGGGAAGACCATGATTGTGGCTTCTTCTACCCCAACTTTGAATGAGAGAGCACTGTAAGCAGAAACTGCCATCAGTCTC
CTGGGCAGGACCTGGAGGTAACTTTCTGAGCTGTAAAATAGTAATTCCTAAGAGAGCTTACAAACTGCTTCCACACAGAAAATAGCGCAG
GGAGGACAGTTATTAGTACCCCTATTCTAGAAGAGAAAGCTGAGGCTCAAGCCATTAAGTGACTTGCCAAAAGCTGTGACATAGCTGGGA
AGTGGCAGATTTGGGGATATAACCAGGTCTTGCAAGTCCAGTGCTGTCTCCAAAGTAGCCACGCTCACAGCTGAGAACACCTTAGAGGAC
AATATCGACTTCTTACAGACTACCAAGCCCCCAGTCATCCAGGGAAATTCAGAGACCAATTGACTGCCAGGTGGCAAATCCACATGTGTA
CTGCGGTCTTTAGAGATCATTTAGAGCTTGCACACATCTGTGTCTTCTTGTGGGAAACCTCTAGGTATTCTGTCTGATCAGCACTGTGAG
GAAGTTGGTGGGAAAAGGCCACTGATAAGAACAAACAATGGGCAGAAGGAAGCACATTGCAATAAATTTCCCCAGAGAGAGTTCCTTTAC
ATTCCATTCACCAAAAACCTCTCTGGAACTGTCAGGTTCAGAATATCAACCAAGACCATATCATTTAGAATTCATTGGCATGTAGAGGTG
ACTCGATTCCTAAAAGAAGCCTCTCTCCCATGAACCACGATGTACGTTCCACAGAGGCAGAAACCGCCGTAGGTTAGCAATGCATTTTAG
TCTTTCTCTCCATTCACATTTACTGAGAGCACACCACGTGCATGTTGCTGCAACAGGCATTTCCGATAGAGCCGATCCATGAGCTAACAA
TGTCTGAAAACAAATGTTATGGAACTGTTGGCATTTCTGAGATTTGGCCTTTGCCATTTGATAGACTTTGCTTCCCAGGATGCTGTCATT
TTGTGATTTTTTATAATTACAAGGAATTTGGTACCATGTTGTTTTCAAAAAACCTCCTAGAAAGTCTCCATGTATGCTCTAGAAGTTGCT
CTACGTAACAGTTCAGCAAGCAAGTGTTCCTTCTCTTGAGCTGCGTCCCTCAGGAAGCTGTACCTTTAGGGTGTGCTTTCCACTTTTTAT
TTCCTCTCATTTCACTCCTTTCATTGTTTGCTATATCCTAAAATATGTGAAGTGAGAGAAAAAATATCATTTCTTCTCATTAAATCTCCT
GCATTAAATCTAAGAATCCTTTAAAATAATCACACCTGATAAGTGTTTTATGCATTTCCCTCCCTGGAGTGTTATCATCCATCAAGCCAG
TATCATCATCCACCTGCTTATTCCTTGGGACTAATGAGAGCCAAGTTAAATAGCAAATGACTTCTCACCCCTTCCTAGTCCTCATGCCTG
AGGAATAAGGGCGACATTAATGGGAGCGGGAGAGTGGTGGCTTTGGTTGAGATGCACGTTCACAGACTAGAAAAGTGCCTCACCTCCATG
GTGTATATGTGCCACCTTTTCTTAATCCAGTCTATCATTGTTGGACATTTGGGTTGGTTCCAAGTCTTTGCTATTGTGAATAGTGCCGCA
ATAAACATAAGTGTGCATGTGTCTTTATAGCAGCATGATTTATAATCCTTTGGGTATATACCCAGTAATGGGATGGCTGGGTCAAATGGT
ATTTCTAGTTCTAGATCCCTGAGGAATCTCCACACTGACTTCCACAATGGTTGAACTAGTTCACAGTCCCACCAACAGTGTAAAAGTGTT
CTTATTTCTCCACATCCTCTCCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCCATTCTAACTGGTGTGAGATGGTATCTCATAGTG
GTTTTGATTTGCATTTCTCTGATGGCCAGTGATGGTGAGCATTTTTTCATGTGTTTCTTGGCTGCATAAATGTCTTCTTTTGAGAAGTGT
CTGTTCAATACTATGCAGCCATAAAAAATGATGAGTTCATGTCCTTTGTAGGGACATGGATGAAATTGGAAATCATCATTCTCAGTAAAC
TATCTCAAGGACAAAAAACCAAACACCACATGTTCTCACTCACAGGTGGGAATTGAACAATGAGAACACATGGACACAGGAAGGGGAACA
TCACACTCTGGGGACTGTTGTGGGGTGGAGGGAGGAGGGAGGGATAGCATTAGGAGATATACCTAATGCTAAATGACGAGTTAATGGGTG
CAGCACACCAGCATGGCACATGTATACATATGTAACTAACCTGCACATTGTGCACATGTACCCTAAAACTTAAAGTATAATAATAATGAA
ATAAAATTAAAAAAAAAAAAGAAAAGTGCCTCACCTCCCTGTGAGGCTTGATGAATATTGTGGCCAGTGAGTGGAAAATGATTCTTGTCG
AATAGACAGAGTATTCCCACCCCAGGAATGGATTAATAGAAGACACAATTTGAGCACTTCTCAGAATTATCTAGTATGCCTGAGTAGAGA
CTCACATGGGTGGAATCTGTGTTGTCTCATCAGAGGGAATAAAAAGACAATGAGGTGGTAAATGTGAAAAAAGCAGCCTTTTAGAAAAAC
ATTATTTTCAAATACCTTTATAAATCATCTAATTTATCTTCACATAATATAAAGAAAAAACTAATAAAAATTTTCGTATTTCACTTTACA
TAATATGTTCTCCCATATTTAGGGATCATACAATTGTATTGTCTTCAAAACACACACACACACACATACACACACACACACACACACACA
CACACCCCTTCCAAGAAAGCTGATCCTTCAGAAAATAAATCTTATTTTTAAGCACTTGGGTTTTCAGGCCAGAAAATTAATAAATCCTAA
ACCTGACCCATTTTTGTAACAGCTAAAAAGGAGAAGAAAAAGCTAGTTAAATTTTGTGTGGATCCATTTATCTCTTAAAATATGCCAAAG
CAATTTGAGGTGGGGGTGGAAACAGGTATTTATCTCTCATGCGTGATTCTCTCTTTATATTTCTATCTGTTGGGAAAAGGGTAAAGAACT
ATTCTTGGTCATTATTGATGTATTGTGTTGCCACTTTGTATGGTGCCTGCTGTGCTTTATCCCGAGGCATAGCAGTAATCGTTACTATCT
TGACTCTTTCCTTCATCACAAGAGAGTAAATATGAAGTCTGAATGTCGTTCCTCACCCCCAAATTGTTTAACTCTGCTTCCAAACTAGTT
TAAGAAATGCAAAATGGGAAGAGCTAGCTTTTCTTAGATACATTTCTTCCTTTTTTATTCTTTCTTGGGAGACGTTAAGTATAAAAGGGA
AAAAGTCAGTTCCTTCTTCTCTCTCTTTCTCTTTGGGTGACAGCAATGCTCACTTAGTAATTATAAACTGGAAATAGGAGAGTAGCTTGA
GCAGGTTATGATATATCTGCCCAATGTGTTTCATTCCTTCAAACATAAACTTTGAGAGTAAAAGAGATTTTTATAATTTAAATGCCAACG
ACAGGAATGGCCTCATGTTTTAACTTTCAAATAATAAATGGGGAGTTGGTATTTGGGCAGAGTTTGCATTTTACTAATCCTATATACTTT
GAGCTTAGTTTTTAGAATTGTGTCAAATACATCAACATATCAGGATTATAGTGCCAAAAATAGTTAAAGTGCCTTGGTCCTCCCTCTGTA
GGCAGCAAATTGAAACTAACATGGGACCATGCCATCCTTCTAGCATAATGGAGAAGTCTGAACTGAGGAGTATCTTTGATGAAAGACATT
TAGGACCCTAGAAACTAAATCTTGTCACCAAGACTTTATAGTAAAGTAGTAGCAAAATTATTTTTAAAAGACTTTCTTCCTTTTACTACC
CATTTCCTCTCTTGGGAAAGCTGATGAGCAAATTATCCAAGACTCATTTCTTTATTAGGCAAAGTCAGAATATTTCCCCTCTGAAAATCT
GAATTATGCCCTCATTCTTTTTCAAGAAATATCTCAAAGAGCAAATAGAATTAAACATGACACTTGATTGTCTGATTATTTGGCATGTAT
AAAATTATCATGTGGCTTAATGTGCCTTAAGTGAAAATTTAAACTTAGACCTGAAACCTTTACAGTTGGATGTAGCGTTGAGCTTTTGCA
TGTTTTCTGTATAATAAACCACTTTTGTTTTGTTTGTTTTGTCTTTTAACCTACACCTTTATCATTACTCTAACAGATTTAGGGCTTCTC
TTTCTCTACAGCTAAGTAAGGGAATATGTGCAATTATGAGACATACAAAAAAGGAAAGGGAAAGGACTTTCTAAGTAGCAAATCTGTGCC
ATGAAGTAGATGTGGCGTGAAGATACAGAGCCTGAGGATAGTAATTTTCCCTGAGCCACGCACACAGGCTTTTATTTCATGCCTTTTCTC
TTTCTGTGCCGTCACCTTTGAGAAAAACGATTGCACCTTCTCCAAGTCTGCCTTTTTAACAGCTACAGTTAAGTTGGCAAGACTTCCCCA
GCTCTGAATATAGCCATTTGCCGACTCCGGCCTCTTTGCGAGACTGACTCAAATCTGTGATCTTCTGTTCAGCATACACATCAGCAAAGT
GAGAAGATGAGCACTAAATATAGGCTCTATTAACTTTACTTTTAGATTTACTGCCTTCAAAAAGTGCCTATTCTGAGCAACATAAACGTT
ATTCCTTACATATGTATGTACACACGGTACCCAGAGTCGTACTGTGCAGCCTTCAAAAACATACCATCAGAAAGAGTAGGTGCTGAGATA
AGGAAACTTTGCCAAATGAAAGAAAGTCACTCACTTCCAATATCCCCTCTCAAGCGGCTACCGTGAAACGGGCTGCAAACACATTCCCTG
AGCATCCCTTGCTGATACAGCTTCTTTATATTTATATCCTACTGGATGGTAGCATATTGCTAAGGTTTCCTGTACTCTGCTTCAAGGGAA
TGTAAGCTTTATGGCATTGAAACATTTAGGGAAAAAAAAGATGTTTAAGAGAATTAATAGAGCCGTAGTCTGTATTAGGATGTGTGTCAT
ATGTGTGTTCTATAAACTAAGCATCGGTGGGTTTAGAGTGTTAAAGTGTCAGCACATTCCTTCTCCTTTTGTCTCTCAGGCTAACATGAG
AGAAAATAGAAAAGTCTTGGCTGTGGGGATTGGAAGCTCAGGGGGCCAAATGTCCTTGCCAGATCCTTAGAGCATTACTTTGACTCCTAA
AAATAGTAGTGTATGTTATTTGATGGCTTTTGTTTCCATAGTTCCATCACTGACAAAACTGTCAATACTGTTGATGGAGCAGCAGCATAG
CCTAGAGTGATGCATTCTTACCCAGAGGTGGCAATAGGAGAGGGTCCATGTAAATAGGACGAGGTAGACAGTGCATGATTGTAGGAGAAG
GGTTGAAGGGAGGACATGATTCCAAAAAAGATCGTTCTCAATGTGTCGTCTGACTCAACCAGCTGGCAGATTACACTTGCCAAGTCGTTC
CCTTTCCTTCTAAGTCAGTTGGCTCCATATTCACTTGAATATGCCTCTGTTTGGGCAAAGCAAGATACCTCCACTTAACCTTTATCCAAG
GAAGCTCTTGGTGTCCTCTTGGTCATAAAGTTGTCTCCTACCTAACCCAGTTTTACCAAATGGAAGTAAAAGGGGACAAACTATGGAAGA
TGGACTCCATGCCATTGCAGTCAGCCACCATTCTCTTTTCCATATAAGGAGCCCCATTACATAAGCTACGGGTGAGGTTGGAACAGCTAT
GTTTCATAATTTCAAGAGTGTGACCACCCTGCTCTAGTCATCATCATTGGATGAATCCAGTTGACTCTTTGGCAAAAGGGTGATACTTTT
CACTAAAAATGCCTACTCTTCCTGTTGATGTTCCTTTTCTGTTTTTACCTTGTCCAATTTCCACACTAGTCATTTTTTTTATTTTTTAGA
GGATCAGATTTTAGCGCTGGAAAATGAGTTCAAAAATTTCAGTGTAATGTCATAAGGATGTTGGGATACAGAGATTTTTTTTTTCCTTGG
AAACAAATGGACTGGGAAGAAACACAGCATGGCTTTGCTCTGAGTTTCAATCTGATGATTATGACCATGGAAGATAGTCTTATGTAAAGG
TTAAATGGTGTTTACAAGTGGATAGATAAGGCGGAGATGGTGAGAAGCCGGGTTTTCTCTATGCTAAATGTGTCTACTAAGAGCAGCACT
TCCTACTAGCTAAGCACAATCATAGCCCCACCGTGATGAGCTGCTAGTCTGAATAACATTCCCTGACTTAGGGAAAGGCACACAAAAACA
TATAAAGAATATGTCTATTTTCATATGTGTGATACTGACAGAGCCATGGTATTCCTAAAATATAGGTTTCTCTTTTTTCTTGTATTCTTA
GCAAATTGCATTTATTCACTACATTACAAACCATCACTGATGTATCCAAAATAGCACACATAGTTCAGTATGAAAATAAGAGAATAAAAT
CTGTTATAAGCAAGTGATTTAGGTATTTTCTTTTGTGTTTATGCATTATCTGACTATATTAAAACCTGTTTTTCTATTTACCTTCTATCA
GTTTTCTCTACCAATTATGTTTTTTCAATGCTCTATAAGAATGAATATGGAAATTATATTTCTTTTTTCTGTAAAAGAGTTGCAACTACT

>52502_52502_1_MECOM-LPP_MECOM_chr3_169381124_ENST00000494292_LPP_chr3_188242453_ENST00000312675_length(amino acids)=496AA_BP=
MDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPV
PASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRY
YEGYYAAGPGYGGRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPSSVAPS
FRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQC
NVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHC

--------------------------------------------------------------
>52502_52502_2_MECOM-LPP_MECOM_chr3_169381124_ENST00000494292_LPP_chr3_188242453_ENST00000448637_length(transcript)=5518nt_BP=135nt
AGAGAGAGGGAGGGAGCGAGAGGGAGAGCAAAAGAAGGAAAGGATCCAAGAAAAAAAAGCCCCAACCACACACCAGCGGCTGCAGGACTG
GGCACAGCATGAGATCCAAAGGCAGGGCAAGGAAACTGGCCACAAGGGAATCCCGGAGGCAAGACACTTGAGGAGAGGCGCTCCAGCCTG
GACGCTGAGATTGACTCCTTGACCAGCATCTTGGCTGACCTTGAGTGCAGCTCCCCCTATAAGCCTCGGCCTCCACAGAGCTCCACTGGT
TCAACAGCCTCTCCTCCAGTTTCGACCCCAGTCACAGGACACAAGAGAATGGTCATCCCGAACCAACCCCCTCTAACAGCAACCAAGAAG
TCTACATTGAAACCACAGCCTGCACCCCAGGCTGGACCCATCCCTGTGGCTCCAATCGGAACACTCAAACCCCAGCCTCAGCCAGTCCCA
GCCTCCTACACCACGGCCTCCACTTCTTCAAGGCCTACCTTTAATGTGCAGGTGAAGTCAGCCCAGCCCAGCCCTCATTATATGGCTGCC
CCTTCATCAGGACAAATTTATGGCTCAGGGCCCCAGGGCTATAACACTCAGCCAGTTCCTGTCTCTGGGCAGTGTCCACCTCCTTCAACA
CGGGGAGGCATGGATTATGCCTACATTCCACCACCAGGACTTCAGCCGGAGCCTGGGTATGGGTATGCCCCCAACCAGGGACGCTATTAT
GAAGGCTACTATGCAGCAGGGCCAGGCTATGGGGGCAGAAATGACTCTGACCCTACCTATGGTCAACAAGGTCACCCAAATACCTGGAAA
CGGGAACCAGGGTACACTCCTCCTGGAGCAGGGAACCAGAACCCTCCTGGGATGTATCCAGTCACTGGTCCCAAGAAGACCTATATCACA
GATCCTGTTTCAGCCCCCTGTGCGCCACCATTGCAGCCAAAGGGTGGCCATTCAGGGCAACTGGGGCCTTCGTCAGTTGCCCCTTCATTC
CGCCCAGAGGATGAGCTTGAGCACCTGACCAAAAAGATGCTGTATGACATGGAAAATCCACCTGCTGACGAATACTTTGGTGAGTGGGGC
CTAGAGCTGACTTCTGAAGTAACTATCTTGCTCTGATTTCCTTCCTTAGTAATTGGAACTATTATCAGCTCCACTGGTAAAGTATTTGAG
TCCAGATGCATGAGAGTTGATATACATCCCCGCACAACTAAGTAATTGTAGGATTTGCATTTGCAAGACTGCCATAGATGTGATGTCTAC
TTAGCTTATACTAAAATTTCAGTGGTCCTTAGAGTTTCCTTAGATACAAATTTTATTGTTGAGACTTATTTTTTACCAGTCTAGGCAACA
TGGGGAGACCCTGTCTCCATTAAAAATACAAAAATTAGCTGAGTGTGGTGGCATGTGCCTGCAGTCCCAGCTACTCAGAAGGCTGAGGCT
GGAGAATCACCTGAGCCTGGGAGGTCGAGGCTGCAGTGAGCTGTGGCTCAGTGAGCTGTGGTTGTGCCACTGCACTCCAGCCTGGACAAC
AGAGTGAGACCCTGTTTTTTTGTTTTTTGTTTTTGTTTTTGTTTTTTGTTTTAAAAAAGAAGACATTTTTTGACAACTTATTAGCTTCCC
ATTAGGCAGAAATAGGATTTCTGTGTATGTTCCCATTTCTCACTGGTCTAAAGATTCAAGTAAAAAATGTGGAATTGGATATTGTCTGAT
ATCCAATTTCCAGATTGTACTCTTAATTTTTTTTTCTATCTCAGTTGAAGAAATGATGTTTTCTTTGTAGTTTTAATTTTCCCCTCTTCA
AACTTGTTAATAACTAGGAATGGTTAATCCTTCCAATCCATGAATATAATGCAAATTTATGAATTATATGCCGATTGTGAGGTTCTGTGG
ACGCATAACCTGTCCTCAGTGAGGTTAAAATTGTTCAGAAAGAGGTAAGACAAGCATACAAATAATTACTAGTCTAGGTAGAAAGTGATA
AAAGACATGAGAAGGCTTAGGTCAATTGTTGCAAATTTTATTTTTATTTTATTTTATTTTATTTATTTTTGAGACAGAGCCTTGCTCTGT
CACCCAGGCTAGAGTATACTGGCGTGATCTTGGCTCACTGCAACCTCCACCTCCGGATTTTGAGCAATTCTCCTGCCTCAGCCTCCCGAG
TAGCTGGGATTACAGGTGCCCACCGCCACACCTGGCTAGTTTTTGTATTTTTAGTAGAGACGAGGTTTCGCCATGTTGGCCAGGCTGGTC
TTGAACTCCTGACCTCAGGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCGCCCGGCCAGAAGTTT
TAAAAGCTCCATTTATTAGGAGCATCCGGAATACTTTGGTAAAGAATTGGTGGCACTTGAATCTGAGCCCTTTAAACCAGTGCCTTTCAC
ATTTTCTGTGGTAGAAGACCATTTTCCTCCCAATCTGTTGGAGACCAGTATTTTTGTTGAGTCAGTTAAAATTAATTACTAGGGAAATAA
AAGACACAAAATAAAATGGAAGATGAAATTTTATCATTATTAGAGTTAACTGTTAACGAATTACTCTTTTAAATTTTTATACTAGTTTCT
AAATATTAATCCTTTGTTCCTGTATTTATCTCATCCAGGGTGATAAGCATTTCTTAGACACCCATCCATGGACCACTTTTTGAGTGGCAC
TGCTTTAAGGACAAATAGAGAAACGACATTTGGGGAACAGTATTAGTAAAGGCACAAAGATGGGGAAATTGCACAGGATTTTTGCTTCTT
CAAATATTTTCTATTTTCATGTCTTTTTTGCTCCTATATGGGAATATGTAATGACAGGTCAACTGACCACACCAGTCCAAAAACACACAG
TAGATGAAGTAGGAGGTATTAGGATATGAAAACCCTGGCTTTTATTTGTGTTGGGGTGGCAGTTTAGCTTAGCTAAAAGAGCAAAAAGAG
TGGGAATGAAACATCTGGTTGTGGTCTCTTCTCTGTCCCTCGCTGGCCAAGCAATACTGGCATGTCACCCATCTGCCTGAGCCCCATTTC
CCACCTCACTATATCAACGGTTGGGGCAAATGTTCTCTAGCATTTCTTTCAACAGTAATAAGTTCAATGTACAAACATCCTTAATCTAAA
GTATAACAATAAAGCTAAACATAAATTGATGGAGATTAACAACAATGCATGGAGAACAGTAAAACAAAACATAGAAAATCCACGAAGGTT
TCTAGTTACATCAAAATACACAAAAAGTTTATTAATGCTCTTGTCATTGCCATGTGAGGAGGGTTTATAATGGGGTCTAAAATACATTTT
TTAAAAGTGAAAAATAAGGTCTCTGTATTTAGGTCCTATTAAAAAGGAAAAGCTGACTTACCAAGTATATATGCTTCAAATATCATAGCA
ACAAAATATATTGCCACAAAAAAAAAACTGAACATAGATGCTAATTGCATGAATGAATATATATTGAACACTCTGGGAAACAGATATAAA
TTATTACCTTTCCCTTCAAGAACTGTCCAAGCTCTACTACTTAGTAGCTTAGAAAACTTGAACAAGTATTATTCCCTCTAAACCTTCATT
TTTGTTTTGTTTTATCTGTAATATGGGAATAATAACTAGCTTATACTGTTGTTTTAAGAAATGGATGAAATATTTATACAAAGCACTTAG
CCAAGTTCTTGGCATGTAGAATATGCTCAATACAATACTCAAGGTTCTCCCATGCTCTTGGGGCTTATAGTTTATTTAAGACATAAGATA
TGCTCGTTAAAAATCCATTAATAATGCTCAATTTAAGTTTAAGTTCCTAGCAACAATAGAACGTATGTCACTGGTAAGTAATCATTGCCA
AATGGGGATGAATAACCATTTGAGAATTTGGAAAAATGGCTAACTTTTATTGAGTGCTTATGATATGGCAGCACTATATTTTATTTACAT
TATAGGAATTAACTCATTTCACTCTTATAGGAAAACATAACCCTGTGAAATAGATACTATTATCATTTTCAGATTTTGAAATTAAGGCAC
AGAAATATTAATTTGCCTAATGTCAACAGCTAATACATTGCAGAACTGAATTAGAATGCAGATCTGTACATTTACACACCACACTGTAAA
AGATGGGGAAAGCTAGCCAGGCTACATATTTAGAAGAGTGTTTATGGTGGAGATTAGCTTTGGACAGATGGGAAATAAGAGATGAGCATT
CTCTTCTAGGTACACAGAATTAACAAAATATAAGTTGAGGCCAGGATTATTTAAAGAAAATTTACGTTATGTAGAAAACAAAAAAAAAAG
TGCCTATGGTAATATTCAGGCTGCTCTGCTAGGTGGTGGTGGGGGTAGATGTGGGTCTTACCTTTGAAGTTCTTATAGTCTAATAGGATA
TGTGTACAGAGTTATGGTGTTATAAGCACAAGGCAGAAAGTGACAAGTGACTTAATCAATGTTCACCAAGTGTTCTTTGAGAATTCAGAA
AAAGGAAAGAGAAAATCAAGAGAGAGAAATGGAAAAGTATTTATGGAATACTTAGCCTTTGAGTAAGTCTTTAAAATTGTGCTAATTGAG
ATTTGGAAGTAGGAAGATAGTAGAGAAGTGAAGTCATTTCTCATGAGGGGAGTTTTTGACATAACAGGGAATAAAACCACTGGAGTGAAG
TGTCCACGTGAGAAGTAGCAAATATTGGGAAATAAGGTTCAAGTAGTAGGTTAGGACCAATCTAGGGAAGGCTGTCAATGTCCGGCTAAA
GGCTAAGAACGTTATTGTCTATAATGAGCCCTTGCACATTGAGATCACATGCCATGAGAACTGCTCTGTGGATAGTGGTTAAAAACATGC
ACTCCAGAGCCAGGATGCACTTCTTACCAGCAAGATGAAATCAAGAGGCAAAGGACTAGTGAAAAGAACTGTCCTTTATTGTTCCGTGCT
TTAAACATTTCTCAAGCACCTTCTCTGTGCCTGCTACTGTGCTGGGTGTTCAGGACACCCAAATGCAGAGGCTCTGCCCTCATGGGGCTC
ACGGGTTCCTAGGAAGGACAAGAGAGTCACAGATGTCAAGGATTTTAGTGCAGATATTAGCACTGTGTTGGGTGTGACTGAGCTGCTATG
TGAGAGTCCATAAGTCTGCCTGAGGATGAGCGGAAAGAATACATAGCAGTGTGTTTGCATCAGCAGGGCCTGACCCAAGAGCGATAAAGT
CTTCTCTTCCTTTCTGTCAGAGTTTTACCTTTGGCCTATTCTGGACTGCAAATAGCATTGCCAAGCACTTCCCTTAAATAACTTCTCTTT
TTTGCAGGACTATCCTCTCAGCCCTGCCAAAACCCCATCACCTACTCTTTCTTTACTACTTTGCCTATTTAATGCTGGAATTTTTATTTA
AACTGTAGCTGATTTACTGAAGGTAATTAAGTGCTTTCATGCTGTAGATCTCCTGCTAGACTACAGGCTGTACTTGGGAGTGAGAGTGAA

>52502_52502_2_MECOM-LPP_MECOM_chr3_169381124_ENST00000494292_LPP_chr3_188242453_ENST00000448637_length(amino acids)=312AA_BP=
MDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPV
PASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRY
YEGYYAAGPGYGGRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPSSVAPS

--------------------------------------------------------------
>52502_52502_3_MECOM-LPP_MECOM_chr3_169381124_ENST00000494292_LPP_chr3_188242453_ENST00000543006_length(transcript)=17861nt_BP=135nt
AGAGAGAGGGAGGGAGCGAGAGGGAGAGCAAAAGAAGGAAAGGATCCAAGAAAAAAAAGCCCCAACCACACACCAGCGGCTGCAGGACTG
GGCACAGCATGAGATCCAAAGGCAGGGCAAGGAAACTGGCCACAAGGGAATCCCGGAGGCAAGACACTTGAGGAGAGGCGCTCCAGCCTG
GACGCTGAGATTGACTCCTTGACCAGCATCTTGGCTGACCTTGAGTGCAGCTCCCCCTATAAGCCTCGGCCTCCACAGAGCTCCACTGGT
TCAACAGCCTCTCCTCCAGTTTCGACCCCAGTCACAGGACACAAGAGAATGGTCATCCCGAACCAACCCCCTCTAACAGCAACCAAGAAG
TCTACATTGAAACCACAGCCTGCACCCCAGGCTGGACCCATCCCTGTGGCTCCAATCGGAACACTCAAACCCCAGCCTCAGCCAGTCCCA
GCCTCCTACACCACGGCCTCCACTTCTTCAAGGCCTACCTTTAATGTGCAGGTGAAGTCAGCCCAGCCCAGCCCTCATTATATGGCTGCC
CCTTCATCAGGACAAATTTATGGCTCAGGGCCCCAGGGCTATAACACTCAGCCAGTTCCTGTCTCTGGGCAGTGTCCACCTCCTTCAACA
CGGGGAGGCATGGATTATGCCTACATTCCACCACCAGGACTTCAGCCGGAGCCTGGGTATGGGTATGCCCCCAACCAGGGACGCTATTAT
GAAGGCTACTATGCAGCAGGGCCAGGCTATGGGGGCAGAAATGACTCTGACCCTACCTATGGTCAACAAGGTCACCCAAATACCTGGAAA
CGGGAACCAGGGTACACTCCTCCTGGAGCAGGGAACCAGAACCCTCCTGGGATGTATCCAGTCACTGGTCCCAAGAAGACCTATATCACA
GATCCTGTTTCAGCCCCCTGTGCGCCACCATTGCAGCCAAAGGGTGGCCATTCAGGGCAACTGGGGCCTTCGTCAGTTGCCCCTTCATTC
CGCCCAGAGGATGAGCTTGAGCACCTGACCAAAAAGATGCTGTATGACATGGAAAATCCACCTGCTGACGAATACTTTGGCCGCTGTGCT
CGCTGTGGAGAAAACGTAGTTGGGGAAGGTACAGGATGCACTGCCATGGATCAGGTCTTCCACGTGGATTGTTTTACCTGCATCATCTGC
AACAACAAGCTCCGAGGGCAGCCATTCTATGCTGTGGAAAAGAAAGCATACTGCGAGCCCTGCTACATTAATACTCTGGAGCAGTGCAAT
GTGTGTTCCAAGCCCATCATGGAGCGGATTCTCCGAGCCACCGGGAAGGCCTATCATCCTCACTGTTTCACCTGCGTGATGTGCCACCGC
AGCCTGGATGGGATCCCATTCACTGTGGATGCTGGCGGGCTCATTCACTGCATTGAGGACTTCCACAAGAAATTTGCCCCGCGATGTTCT
GTGTGCAAGGAGCCTATTATGCCAGCCCCGGGCCAGGAGGAGACTGTCCGTATTGTGGCTTTGGATCGAGATTTCCATGTTCACTGCTAC
CGATGCGAGGATTGCGGTGGTCTCCTGTCTGAAGGAGATAACCAAGGCTGCTACCCCTTGGATGGGCACATCCTCTGCAAGACCTGCAAC
TCTGCCCGCATCAGGGTGTTGACCGCCAAGGCGAGCACTGACCTTTAGATTCAGTCACCTGTTCAGCCGGCACTGAGAAGAACGAACACA
AGAAAAAGATAAGAAATACTAGAGTAAAGGCCATCAAACTACGCGATAGTCTCTGTTCTTCATCTGCTATTAACCTTGCCTTAGAAACAC
ATAAATTATGAGATTTTTTTTAAAAGTTGTTACCAAATACACATTTCACATTGAATCATGTAGGATCTTGATGGGCCTTTGTTCCCAAGG
ACTTCCACATTTTTGCACAGATTATGCTCCATCCCATTCACTTCTGCATTCCTGTAACTTTTAATCCCTATGTTTGTCTCACTTTTCATC
TGGTTGAATGGCTTTTCTTAGTGTGGTATTTGCTGTCACATAGTTTTTCCTGGGTGAGTCTGCCAACTCACAGGTGCTTTTAGGCTTGAA
ATCTCCATCCTATCATTTCCGTTTTGCCTGTGACTGTAAAGAGTAGCCATTCTTTTCCCATGTATTGAAGAGGATATTCTTCTCTTGCTT
TATACTACTCACGTCCTTGGGGAGGGAAATGCACAATTTTTTTTTGTTAGGCTGTAAAGAATTTAAGCTGTAAATTACATAAGTTAGAAC
AAGCCCAAATTTAATTTGCAACCATCAGAATTCAGAATCTATAGTGACCAGTGATCAAGGCTAATTGGAAAAGAGTTATCGGCCCATAGC
TAATAAGTAGTGACAGACAACCAAGCTTCAATATTTTTCTAAAGAAATTACAGGTGGGATATGCTAGAAAAGGCATTTTGGGGTTATGTT
TAAAAAAACATTATTGTCCCACAATATTACCTTAAGATTTTTCTTTTCCGCACTACCTGAACATTGTAATACAGACAAACTTGATTTCTT
CTAGAAGATAACATTTTCAATACTGTCCCACTTCTCATCTTAAAAATATTGTCATGTTTATTCTAATATCCAACACAACTATCAAAATTG
CCTTTTTCTCTAGAGGATGAAGGCTGTGAAAAAACCGTTCAAATTCTCTTCTTTTTCTTTTTTATTACCAGGTCCATTTTGCCTGACAAT
TGCAAATCAGAGCATACAAAATAAAACTGTGCAGTTTTGTTTGGTTTACTTTCAAAAGAGTAGAAAGCTTGAAAAGATTCTGAAACCACA
GTTTCATTATTCTCATAATCCTTCTGCAACTGAAATTACATATTGCAGGAGACATTTTCATATCATCAATGTGACATTTACACCACACTT
TCAAAGACAATCACTGAAACAAAAATTGTCTTTATGAGCTAAAAATATGCAGAATCTCTGCCTAGAATCTTTATTCAAACTTTTATTAGC
CAGTGAAACACTTGCTTGCCAACTGCCAAGCCATACTTATTAAGTTCGAACATGTTTCACTTAAGGAGAGACACCTAGCTTAGTCATGGC
AAGTTGCCATTTTGTAAACTAAGGATTTTGGACTGAGATTTCTTAAATCTTTCTTCAAATCTCCCACAAGTATATACTTTTAAATTATGG
AGTATTTTAAGTCTACAAAAAGGTATAAATAATAATATAATGAATTCCTATATACCTAATACCCAGTTTAAGACACCAAATATAACAAGT
ATAATTACATCCTCCAATGTACCGTTTCCTTATTCCACAGATATCTTTTTCATTATTGTGAAGTGATGTTCAGATTTCTAGTTTTTTTTC
TAGTTTTTAATTTTAACATCAGAACTGAAATAAAAAATTATGGATACGTGTTTTGAATTGCAAACTATTCCTCAGGAATTCCAATTAAAT
TTATTTTACTTGAATAGGAATGATCATAAAAGTGATTCTTTTTTTGTGACTAGAAATTCTTAAGCCGATGGTCACTATAGCTCATCCTTA
ATGTATGGCTCATTTGCTTTTGTCACTAAACGGTTTTGTGTTAGAACCACCAAAATTATAGCTTTTAAGAGCTTCCTTTGACCACTGTCT
TTTTCTTACCCTAGTTCTCTTATCTTTGATCGTATATTTCTCATAATGTGAAATATGATGAGATTCACTTAGGGGCAGCATGTTAGTTTT
GGGAGGCAATGTCAACTGTGTCTCTGAATTCCTGTCTTCCAAATTGAAGCCAGACCATGCTGATGACCTCAAGTAGCACTGACTATTTGA
CAATAGGGCTGATAATGTAATCGGCTTGAATTTTGACTTAGTAACTTTTTATGTAATACTTTCGGAGAAATTCTCTTTAGGACAAAGCAG
AGAGTCCAATTTATTGAGGGATAGATTGTATCTCTTAAAGTGGTCATATTATTATTAATTTTGCCAAAAGAAGAAGAATTTATTGAATAT
TTATACTATAAAATGCAGTAACATTCTACTTGCTTATTACATTTAAATCCTTGTGTAACTGAATGTTTACATGTCAAGAGGAAAAGCTGT
AAGAAAATGCTGTCACAGACCCATCCCTGTGGCATCGTCAGCAGAATACTGCTTGCTTACAATCTTTATTATGCATTCTTATAACATAAC
CTCAGAGTATCTTTACCAAAGGTTTTTAAAGTAAATCTCTTTTTAAGATAGACTTATTCTTTTATAATAATGAATGTGCACTCATACATA
TGTAGAAACATTTAGATTTAGAGTTTTTTTTTTCTTTCACAAGGTATAATAAGGAAAGGATCCTACAATATTTTATTCTAGGGTTTCTTA
AATATATGATTTATATTACTGTCTTTTCTATTAATCATTTGATTTAAACAATGCCAAGTCACTCTTTTTTAGTTGCATGAAATTTTGCCT
GCAACAGAGAGAAAAAGATTGTATTACTTTAATGATTATAATCATACTGTCTGCTGATATAATATCATAATTGTTGTGGTTTAAATACAT
AAATAGTAGAAAAATCAGAGTCTATAACAGAAAGTTTGTAAAAATATACTGATTTTGAAAAGTATCAGGAATATAAATATTTGGTAATTC
TGTGTAACAAGAGAGACATGGAAAAGGAAAAAAATCCACTATATCATGGGCTCTGCAGAACATATCAAAATAGGATTTCTTAAATTTTTC
AACCCCCAGACCATACTGACTCAACATGGAGTCTCACTGGCCAAGAAAATTGCCTTTAAAACTCGAAAATAAGGCCAGGTGTGGTGACTC
ACACTTGTAATCCCAGCAATTTGGGAGGCTGAGACAGGAGGATTGCCTGAGGCCAGGAGTTTGACACCAGCCTGGGCAACATAGTGAGAC
CTTGTCTCTACAAAAAATAAAATAAAATAAAAACCAAATTAGCCAGACATGGTGGCATGCGCTTGTTTAAAAAAACAAATAAATAAATAA
TCGACTCAAAAATAAGTCATGTGTCCCAGCATAAGGCATCAGGTTGTTAGATGCTGGCATCTCTGCAGCTCAAAGATGTGGGTTCTTTTT
CTTGTCATTAACACATTGTTATTTCTGTAGGAGCAACTTCTCTGATCAAAATTACTTTTCTGGGTATGTGCTGATTAAGGGGGTGGACTT
ATCAACACTATAATTGTTCCCTATGAAAGATTCCACAGAGATGTTTATGGTGAGGTTTAAAGGATATGAAACTCTACATTTAAACAAGTA
TTTTATATTTGGGTACAGAGGAAGAAAGAGAGGGCTTTTTCCATGGGGCTATAGTAGAGAGTTAGTGGAATATAGACAGGACTCTGAAAA
CACAACTTCCAGCCATTTTTTTAGTTAGTAAAAATCCTATTAATGTGAACCAGCCAGGAATAACAGTGTTATTTCTATTGGATATGGTTT
GGGCTTCTCTTGTCAAATCTGTGTCGGCTGCCCCCTGATCCTTCCATTATCAAGTTTTGAAGGGTGTTGGGGAAATTATGGCAGCTGCTA
GGGAGATCAGGGAAACACTGATGTAACCTCAAAGCCTCTCACCATTCCTCTTGGCTTGGAAAGGCTTTATTTTTTCATATACATTTCTAG
AAATATTGCTATTCTACCTTAGTATTTCACATTTGTAGTTCAAACAAGCGATTGTCCATCTGTTGCCTAGAGCTATAGTACATGTGTGTT
ATGAATGAAATATGACAGCATGTTCCATACCCCTGCTTTAGCCATCTGTGGGAAACCAGCAAACTGAAAAAGACACCTCTGCAAAATGTG
CCTCAAGTCCATTTCTTGGGATCGCTCGTTTGGTGCACTCTCGTGGGAGACAATCAGAGAACAACATATACTTGTGCCTTATTTTCAAAG
AATCTATTTACACTACTATGAATATTCCACTGAAGAGTCAATGATGTAAATGATAACCACCAAATCTCAAAAATATACTCACCAAAAAGT
AAAAAAGTAAAAAAAAAAAAAAAAGAAAGAAAGAAAAGAAAGAGAGAGAAGTCAACTTTTCATCTTAATATATTCTAGTAGTATTTATTT
TTTCCTTGTCTTGGAAGTATCTCATAGGTCTTTAAATGAGTAAAACATTTTTATGCCAGAAGGTGATATAATGGATGTTAGTGTTTTTTA
TTTGATTTTACAGTAGTTTTAGTCAGATAATGAGGACAGAGACTTCAACTTGATTCTTTACCACCATTCAGCATATTTTTTAATTGTCTT
CATTGTATTTGCTTAATAGTGGTCCAGACAAGTTCAAAACTTGTTCTCAGTGAGGCATTAATATGGTGCAACCATGAATATTTCAGGCCA
AGTTATTCACTTGACAGATAACTAGAATGAAACTTTTCTCATGAGGCTGTTGTTTGGTTAGCATAGCCTTATTTCAAACCTTAAAAAGTT
ACCTGACTGAAGCTACTATGACTTGGTAAGGATTCTTCCTCTCTTGCTTTCTTCCTCCCTTCCTTTCTTCCTCTTCCTTCCTCCTCTTCT
TATTTTCTTTCCTACTTTCCATCCTACCTATTAGTGTTGCTGTACTTGGATTTTTTGTAAATTAAATCAATGCATTATGATTTTAGGGAA
TTATGATTATATTCATAAGGGGAAGGCTACCAGAAAATATATGTGGCATCCATAAAATCTTCTTTTATAGGGGCATATTTTTTAGGTTGT
ATTTATTCGTAAAGTGAAATGAGATAATAGAGTCTTTCTGTTTCATGTTAATGAATTTTCATCAGGGACTGAGGTCATAGATTCTTGGAA
AATTCATTTGTGACTGATCTAGTTTTCTCAGCTGTATGCAAAGTAATCTTTCAAAGACTAGGTTAAGATTTTTTTTTTAAGTCTGAAGCA
ATGTAACCCCAAAAAATTATAATTTTAATGATGGCATTTTATTTTATTCCATTGCAGCTTGATAACTTTCCTTATAGCAAAGGAATAACT
ATTGTATTTTCAGAATTTTAACACAGATTAACACTTAGCCTGTAAGACTAATAATATATTGTAATAGTTGATACTAAAATATTTTTCAGC
AGGTTGGACAGCACCAGTTTTTCTTAGATCACAGACTACAGGCAGAATTTCCCTTCAATCCAGAAAAAAGGACACTAATTTCCTTTTCTA
TTTAATTTTCCTGGCCCTTGTGCAAAAAATTGTGGACTCTATCTTAGTTACAACATGCATGTCCCTTATTTTGTGGAGAGCTGTGTGAAA
GATGCGTTTTTTTTCTTTTTTTCTTTTTTTTTTTTTTGAGACGGAGTCTGGCTCTGTCACCCAGGCTGGAGTGCAATGGCACGATCTCCT
CTCACTGCAAGCTCCGCCTCCCAGGTTCACGCCATTCTCCTGTCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCTGCCACCACGCCC
GGCTAATTTTTTTGTATTTTTAGTAGAGATGGAGTTTCACAGTGTTAGCCAGGATGGCCTCGATCTCCTGACCTCGTGATCCACCCGCCT
CGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGTGCCCCGCGTGTTTTTTTCTTTAGCTGATTGACAGGTCCCCTTCAAAGTT
ACAAAAAAAAGTGCTAATTTTTGCTGTTAAATTCTGGTTGTTATTTAATTGACAGAAGTCTCTTGATGCACGAATAAATATCTCTACATC
TAGCCTTTGTTAAAAATAAAAATTAATATTCTACAAACACCTACATATACTAGAGAGGGGTGAAACACTGCAGCTAATTCCTTTATAATA
CTTTCAGATGATTGCATTAAGCCTTTCATGTTATGTGGCATTGTTAATTTTTCCTAGATACCCATCCACTTAAGGGCCAGAGAAATCCTT
ATTCATTTAACTCTGGTGGGCATTTATGTAACATACCCAAATAAAAACGTTATTAAACAGCCACAATCGCATTCAGTCAACTTGGCACTG
AATGTAGCTTCTAAAATCAGTTCTCTACCCTACGAATGGAATGTTCTACCAAGAAAGAGAAGCATCACCATGTCATCTTGTGTTCTACAC
CACTATAGAGAGTTACAGTTGCCCCCAAACACGAATGCTATTCCCAAATAAAATAGAATCATGCTTTGGGAGGCCAAGGCGGGCCGATCA
CGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAAAAAAAAAAAATACAAAAAATTAGCCTGGCT
CAGTGGCGGGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAAGCGGAGCTTTCAGTGAGCCGAG
ATAGCGCCACTGCAGTCCGGCCTGGGCGAAAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAATAGGATCATGGCCCTTTTAAAGA
TCTGAATCTTCTCTGTTATTTTCCTGATGAATCACCATCCCATATCTTCTTAGTCCTGGCCAGTATGTAGTTGCGCTCACATACGTCTAT
TCTAGCTCTGTAGCTCCACAAAACAAGTCTTAAGTCCAAATCTTTGCCTCTTCATGTCTGATATCACCAACTCATTCAGCTTTTCTTCAC
TTATTGACATAGTGTCATGTCCTATCACTCTCTGCTGCTTCTTTAAACAGTGGACACAAACATATTTTCTAATTTTCAGTGTACTCAGTG
AAACTTGGCAGTTCACCATGAGTCAGGCTAGGTTGAAAGGCTTTCTTTAGGGTTGAAAGTAAACGAAATTGGAATCACCCAAAGAGAATT
TCCCCAAAAAACCTCAGACCCAGAAGTGTAAAAGCTACAGAAGGATAGAACTCCCATGTCTACAGACAGTTCTGTTACTTTTTGTTCTGT
ACTATTTTGGATGTTGCCAAAATCAAATTCATCCTGAAAACAGGAAGCAAGCTAATGCATATGCCATCCATGAGATTCCCACTTCTGGGT
CAGTTCATATTCCATTCAACCTTTTCCTTTTATCCTTGTCTTCTTCAGAATAAGACATTTTTCCTCCATATTTTCATATTAAATATTAAC
ACTTTATAGGTTCTACTTTAATATATGGACACTTTACAGGTTATACATAAATATTTGCTGGTTGATTGATTTCGAGATTCATTCATTCTG
TGCTCAAATATTTGTACCTAGAGACGTTACATGTTAGAAAAAGTGAGCAGCTTCTTTCTCTAATCATTTAGGAGTCCATATTTTTCTTTT
CTTTTTGTTCTCCCAACATCCTTATCTCTTACTCAGCTCTTCAATTTATAATTACCAAATAATCACTGTTAGAGAATCAGCCCCTAAGTA
ACTTTGATTCTGGCCAACTGTAATAAGATCCAACCACTTAAATCTGTACTTACTCAATAGGAAGGAATGTGACATCAGGAAGAGTCATTC
CAGTGACATTAGTAAGACTTTATGGAGTACATAAAATTTGATAAGAAATCTTGAGCTGATTCTTTGACTTGATTTAGAAGTTGAGAAAAG
AGTATTTAAGGCACAACAGGGAAACATGGGCTATACTCAGAGAAGACCCTCTGCATTGGCCAAAATATCATGGATTCTGGAAATTCCTTC
TTAACAGAAAAAAAAGGCTTCCAAATAATCAGGCTGAATGGGAAGAAAAAGGCATAGAGGAAGCCTGAGGAAGTATTTACTTGCTTTTCC
CATCTCTTTATAATTGGAAGAGAAGATGATCTGCCAAAATATAACCCAGCATGCACAGTATGGACAGGAAGCAGCCCTCCATGAACTTTA
TTATCACAGAATATGAGCATTCTTATTGATCCACAGCTACATCTTCTATTCTTGCAGCAAGGGTACATGTCCTTTGACCCTCCACAAAAG
AACAAGCAGGACATCTCTATTTTCCTATTGAGTCTGAGTCCATTATTAGAAAGGACTTCCCAGCCATCTTTTCTACTTGGTATTAAAATT
CCCTTACAGATTCATTGCTAAGTGCCAATTCTTTTTTTTTCTTTTGAGACGGAGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGC
AATCTCGGCTCACTGCAAGCTCCGCTTCTCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGACGCCCGCCA
CCGCGCCCAGCTAATTTTTTTTGTACTTTTAGTAGAGACGGGGTTTCACCGTGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGG
CCTCCCAAAGTGCCAATTCTGACTCTACTTAAACATCACCTGTATCAGGGAGCTCATTATTCCTTGAGGTCTTACATTTCTTTCAGCACA
TTTTGTTCCAAGCTACACGACTTTAAAACAGAGCCAGCCTTTGGGGCATATGTTCTCTTTGGTGCCACACAAAACCTGTAGTACATGATA
CAGTGTTGCTTCCCCCCTCCTTTTCCTTCCATATATATTTGTTTTGTTTTGGGCATTGCATTACTTTTTTGAATTTTTAAGAATCTCTAA
AATTAGTCTGAAGGATGTTCTGAGGGCCAGACATTAGAATTTGTGAGTTTTTTTGTTGCTGGTTGTACTTTCCTATTTAGAAGACAGACC
GTTCTGACAGTTGTTGTGTAGCTTCATGCCTTCCCCAGTAACTAACCCATGAACAGTACACCCCTTTTATCTGACTTGTTGATAATGACC
TTAAAAATGTTAGGAAATGGGCCGGGCGCGGTGGCTCGTGCCTGTAATCCAGCACTTTGGGAGGCCGAGGCGAGCGGATCATGAGGTCAA
GAGATCGAGACCATCCTGGTCAACATGGTGAAACCCCGACTCTACTAAAAAAAATACAAAAATTAGCCGGGCGTGTTGGCGGGCGCCTGT
AGTCCCAACTACTTGGGAGGCTGAGGCAGGAGAATCACCTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTGCGCCACTGCACTC
CAGCCTGGGCGACAGAACGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAGGTTGGGAAATATTGGTGTATAATCCCCATGTCTAAC
AAGGAAGAAGTCAAAAGCAAAAGATAGTGGTATTGCCGAAAACTCATTATTTCTAGTTAGTTCATCTGTGGAAAAGGATATCGTTCTTGA
GGAGAGGGGTTCTATTATGCTATAGTTTTCTATGGAAATGTACAAATGCTTTCCTCATTGCTCTGGATGACTATTTAGTTTAAATAATAT
ACCTTTGTCATGGGGAAGACCATGATTGTGGCTTCTTCTACCCCAACTTTGAATGAGAGAGCACTGTAAGCAGAAACTGCCATCAGTCTC
CTGGGCAGGACCTGGAGGTAACTTTCTGAGCTGTAAAATAGTAATTCCTAAGAGAGCTTACAAACTGCTTCCACACAGAAAATAGCGCAG
GGAGGACAGTTATTAGTACCCCTATTCTAGAAGAGAAAGCTGAGGCTCAAGCCATTAAGTGACTTGCCAAAAGCTGTGACATAGCTGGGA
AGTGGCAGATTTGGGGATATAACCAGGTCTTGCAAGTCCAGTGCTGTCTCCAAAGTAGCCACGCTCACAGCTGAGAACACCTTAGAGGAC
AATATCGACTTCTTACAGACTACCAAGCCCCCAGTCATCCAGGGAAATTCAGAGACCAATTGACTGCCAGGTGGCAAATCCACATGTGTA
CTGCGGTCTTTAGAGATCATTTAGAGCTTGCACACATCTGTGTCTTCTTGTGGGAAACCTCTAGGTATTCTGTCTGATCAGCACTGTGAG
GAAGTTGGTGGGAAAAGGCCACTGATAAGAACAAACAATGGGCAGAAGGAAGCACATTGCAATAAATTTCCCCAGAGAGAGTTCCTTTAC
ATTCCATTCACCAAAAACCTCTCTGGAACTGTCAGGTTCAGAATATCAACCAAGACCATATCATTTAGAATTCATTGGCATGTAGAGGTG
ACTCGATTCCTAAAAGAAGCCTCTCTCCCATGAACCACGATGTACGTTCCACAGAGGCAGAAACCGCCGTAGGTTAGCAATGCATTTTAG
TCTTTCTCTCCATTCACATTTACTGAGAGCACACCACGTGCATGTTGCTGCAACAGGCATTTCCGATAGAGCCGATCCATGAGCTAACAA
TGTCTGAAAACAAATGTTATGGAACTGTTGGCATTTCTGAGATTTGGCCTTTGCCATTTGATAGACTTTGCTTCCCAGGATGCTGTCATT
TTGTGATTTTTTATAATTACAAGGAATTTGGTACCATGTTGTTTTCAAAAAACCTCCTAGAAAGTCTCCATGTATGCTCTAGAAGTTGCT
CTACGTAACAGTTCAGCAAGCAAGTGTTCCTTCTCTTGAGCTGCGTCCCTCAGGAAGCTGTACCTTTAGGGTGTGCTTTCCACTTTTTAT
TTCCTCTCATTTCACTCCTTTCATTGTTTGCTATATCCTAAAATATGTGAAGTGAGAGAAAAAATATCATTTCTTCTCATTAAATCTCCT
GCATTAAATCTAAGAATCCTTTAAAATAATCACACCTGATAAGTGTTTTATGCATTTCCCTCCCTGGAGTGTTATCATCCATCAAGCCAG
TATCATCATCCACCTGCTTATTCCTTGGGACTAATGAGAGCCAAGTTAAATAGCAAATGACTTCTCACCCCTTCCTAGTCCTCATGCCTG
AGGAATAAGGGCGACATTAATGGGAGCGGGAGAGTGGTGGCTTTGGTTGAGATGCACGTTCACAGACTAGAAAAGTGCCTCACCTCCATG
GTGTATATGTGCCACCTTTTCTTAATCCAGTCTATCATTGTTGGACATTTGGGTTGGTTCCAAGTCTTTGCTATTGTGAATAGTGCCGCA
ATAAACATAAGTGTGCATGTGTCTTTATAGCAGCATGATTTATAATCCTTTGGGTATATACCCAGTAATGGGATGGCTGGGTCAAATGGT
ATTTCTAGTTCTAGATCCCTGAGGAATCTCCACACTGACTTCCACAATGGTTGAACTAGTTCACAGTCCCACCAACAGTGTAAAAGTGTT
CTTATTTCTCCACATCCTCTCCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCCATTCTAACTGGTGTGAGATGGTATCTCATAGTG
GTTTTGATTTGCATTTCTCTGATGGCCAGTGATGGTGAGCATTTTTTCATGTGTTTCTTGGCTGCATAAATGTCTTCTTTTGAGAAGTGT
CTGTTCAATACTATGCAGCCATAAAAAATGATGAGTTCATGTCCTTTGTAGGGACATGGATGAAATTGGAAATCATCATTCTCAGTAAAC
TATCTCAAGGACAAAAAACCAAACACCACATGTTCTCACTCACAGGTGGGAATTGAACAATGAGAACACATGGACACAGGAAGGGGAACA
TCACACTCTGGGGACTGTTGTGGGGTGGAGGGAGGAGGGAGGGATAGCATTAGGAGATATACCTAATGCTAAATGACGAGTTAATGGGTG
CAGCACACCAGCATGGCACATGTATACATATGTAACTAACCTGCACATTGTGCACATGTACCCTAAAACTTAAAGTATAATAATAATGAA
ATAAAATTAAAAAAAAAAAAGAAAAGTGCCTCACCTCCCTGTGAGGCTTGATGAATATTGTGGCCAGTGAGTGGAAAATGATTCTTGTCG
AATAGACAGAGTATTCCCACCCCAGGAATGGATTAATAGAAGACACAATTTGAGCACTTCTCAGAATTATCTAGTATGCCTGAGTAGAGA
CTCACATGGGTGGAATCTGTGTTGTCTCATCAGAGGGAATAAAAAGACAATGAGGTGGTAAATGTGAAAAAAGCAGCCTTTTAGAAAAAC
ATTATTTTCAAATACCTTTATAAATCATCTAATTTATCTTCACATAATATAAAGAAAAAACTAATAAAAATTTTCGTATTTCACTTTACA
TAATATGTTCTCCCATATTTAGGGATCATACAATTGTATTGTCTTCAAAACACACACACACACACATACACACACACACACACACACACA
CACACCCCTTCCAAGAAAGCTGATCCTTCAGAAAATAAATCTTATTTTTAAGCACTTGGGTTTTCAGGCCAGAAAATTAATAAATCCTAA
ACCTGACCCATTTTTGTAACAGCTAAAAAGGAGAAGAAAAAGCTAGTTAAATTTTGTGTGGATCCATTTATCTCTTAAAATATGCCAAAG
CAATTTGAGGTGGGGGTGGAAACAGGTATTTATCTCTCATGCGTGATTCTCTCTTTATATTTCTATCTGTTGGGAAAAGGGTAAAGAACT
ATTCTTGGTCATTATTGATGTATTGTGTTGCCACTTTGTATGGTGCCTGCTGTGCTTTATCCCGAGGCATAGCAGTAATCGTTACTATCT
TGACTCTTTCCTTCATCACAAGAGAGTAAATATGAAGTCTGAATGTCGTTCCTCACCCCCAAATTGTTTAACTCTGCTTCCAAACTAGTT
TAAGAAATGCAAAATGGGAAGAGCTAGCTTTTCTTAGATACATTTCTTCCTTTTTTATTCTTTCTTGGGAGACGTTAAGTATAAAAGGGA
AAAAGTCAGTTCCTTCTTCTCTCTCTTTCTCTTTGGGTGACAGCAATGCTCACTTAGTAATTATAAACTGGAAATAGGAGAGTAGCTTGA
GCAGGTTATGATATATCTGCCCAATGTGTTTCATTCCTTCAAACATAAACTTTGAGAGTAAAAGAGATTTTTATAATTTAAATGCCAACG
ACAGGAATGGCCTCATGTTTTAACTTTCAAATAATAAATGGGGAGTTGGTATTTGGGCAGAGTTTGCATTTTACTAATCCTATATACTTT
GAGCTTAGTTTTTAGAATTGTGTCAAATACATCAACATATCAGGATTATAGTGCCAAAAATAGTTAAAGTGCCTTGGTCCTCCCTCTGTA
GGCAGCAAATTGAAACTAACATGGGACCATGCCATCCTTCTAGCATAATGGAGAAGTCTGAACTGAGGAGTATCTTTGATGAAAGACATT
TAGGACCCTAGAAACTAAATCTTGTCACCAAGACTTTATAGTAAAGTAGTAGCAAAATTATTTTTAAAAGACTTTCTTCCTTTTACTACC
CATTTCCTCTCTTGGGAAAGCTGATGAGCAAATTATCCAAGACTCATTTCTTTATTAGGCAAAGTCAGAATATTTCCCCTCTGAAAATCT
GAATTATGCCCTCATTCTTTTTCAAGAAATATCTCAAAGAGCAAATAGAATTAAACATGACACTTGATTGTCTGATTATTTGGCATGTAT
AAAATTATCATGTGGCTTAATGTGCCTTAAGTGAAAATTTAAACTTAGACCTGAAACCTTTACAGTTGGATGTAGCGTTGAGCTTTTGCA
TGTTTTCTGTATAATAAACCACTTTTGTTTTGTTTGTTTTGTCTTTTAACCTACACCTTTATCATTACTCTAACAGATTTAGGGCTTCTC
TTTCTCTACAGCTAAGTAAGGGAATATGTGCAATTATGAGACATACAAAAAAGGAAAGGGAAAGGACTTTCTAAGTAGCAAATCTGTGCC
ATGAAGTAGATGTGGCGTGAAGATACAGAGCCTGAGGATAGTAATTTTCCCTGAGCCACGCACACAGGCTTTTATTTCATGCCTTTTCTC
TTTCTGTGCCGTCACCTTTGAGAAAAACGATTGCACCTTCTCCAAGTCTGCCTTTTTAACAGCTACAGTTAAGTTGGCAAGACTTCCCCA
GCTCTGAATATAGCCATTTGCCGACTCCGGCCTCTTTGCGAGACTGACTCAAATCTGTGATCTTCTGTTCAGCATACACATCAGCAAAGT
GAGAAGATGAGCACTAAATATAGGCTCTATTAACTTTACTTTTAGATTTACTGCCTTCAAAAAGTGCCTATTCTGAGCAACATAAACGTT
ATTCCTTACATATGTATGTACACACGGTACCCAGAGTCGTACTGTGCAGCCTTCAAAAACATACCATCAGAAAGAGTAGGTGCTGAGATA
AGGAAACTTTGCCAAATGAAAGAAAGTCACTCACTTCCAATATCCCCTCTCAAGCGGCTACCGTGAAACGGGCTGCAAACACATTCCCTG
AGCATCCCTTGCTGATACAGCTTCTTTATATTTATATCCTACTGGATGGTAGCATATTGCTAAGGTTTCCTGTACTCTGCTTCAAGGGAA
TGTAAGCTTTATGGCATTGAAACATTTAGGGAAAAAAAAGATGTTTAAGAGAATTAATAGAGCCGTAGTCTGTATTAGGATGTGTGTCAT
ATGTGTGTTCTATAAACTAAGCATCGGTGGGTTTAGAGTGTTAAAGTGTCAGCACATTCCTTCTCCTTTTGTCTCTCAGGCTAACATGAG
AGAAAATAGAAAAGTCTTGGCTGTGGGGATTGGAAGCTCAGGGGGCCAAATGTCCTTGCCAGATCCTTAGAGCATTACTTTGACTCCTAA
AAATAGTAGTGTATGTTATTTGATGGCTTTTGTTTCCATAGTTCCATCACTGACAAAACTGTCAATACTGTTGATGGAGCAGCAGCATAG
CCTAGAGTGATGCATTCTTACCCAGAGGTGGCAATAGGAGAGGGTCCATGTAAATAGGACGAGGTAGACAGTGCATGATTGTAGGAGAAG
GGTTGAAGGGAGGACATGATTCCAAAAAAGATCGTTCTCAATGTGTCGTCTGACTCAACCAGCTGGCAGATTACACTTGCCAAGTCGTTC
CCTTTCCTTCTAAGTCAGTTGGCTCCATATTCACTTGAATATGCCTCTGTTTGGGCAAAGCAAGATACCTCCACTTAACCTTTATCCAAG
GAAGCTCTTGGTGTCCTCTTGGTCATAAAGTTGTCTCCTACCTAACCCAGTTTTACCAAATGGAAGTAAAAGGGGACAAACTATGGAAGA
TGGACTCCATGCCATTGCAGTCAGCCACCATTCTCTTTTCCATATAAGGAGCCCCATTACATAAGCTACGGGTGAGGTTGGAACAGCTAT
GTTTCATAATTTCAAGAGTGTGACCACCCTGCTCTAGTCATCATCATTGGATGAATCCAGTTGACTCTTTGGCAAAAGGGTGATACTTTT
CACTAAAAATGCCTACTCTTCCTGTTGATGTTCCTTTTCTGTTTTTACCTTGTCCAATTTCCACACTAGTCATTTTTTTTATTTTTTAGA
GGATCAGATTTTAGCGCTGGAAAATGAGTTCAAAAATTTCAGTGTAATGTCATAAGGATGTTGGGATACAGAGATTTTTTTTTTCCTTGG
AAACAAATGGACTGGGAAGAAACACAGCATGGCTTTGCTCTGAGTTTCAATCTGATGATTATGACCATGGAAGATAGTCTTATGTAAAGG
TTAAATGGTGTTTACAAGTGGATAGATAAGGCGGAGATGGTGAGAAGCCGGGTTTTCTCTATGCTAAATGTGTCTACTAAGAGCAGCACT
TCCTACTAGCTAAGCACAATCATAGCCCCACCGTGATGAGCTGCTAGTCTGAATAACATTCCCTGACTTAGGGAAAGGCACACAAAAACA
TATAAAGAATATGTCTATTTTCATATGTGTGATACTGACAGAGCCATGGTATTCCTAAAATATAGGTTTCTCTTTTTTCTTGTATTCTTA
GCAAATTGCATTTATTCACTACATTACAAACCATCACTGATGTATCCAAAATAGCACACATAGTTCAGTATGAAAATAAGAGAATAAAAT
CTGTTATAAGCAAGTGATTTAGGTATTTTCTTTTGTGTTTATGCATTATCTGACTATATTAAAACCTGTTTTTCTATTTACCTTCTATCA
GTTTTCTCTACCAATTATGTTTTTTCAATGCTCTATAAGAATGAATATGGAAATTATATTTCTTTTTTCTGTAAAAGAGTTGCAACTACT

>52502_52502_3_MECOM-LPP_MECOM_chr3_169381124_ENST00000494292_LPP_chr3_188242453_ENST00000543006_length(amino acids)=496AA_BP=
MDAEIDSLTSILADLECSSPYKPRPPQSSTGSTASPPVSTPVTGHKRMVIPNQPPLTATKKSTLKPQPAPQAGPIPVAPIGTLKPQPQPV
PASYTTASTSSRPTFNVQVKSAQPSPHYMAAPSSGQIYGSGPQGYNTQPVPVSGQCPPPSTRGGMDYAYIPPPGLQPEPGYGYAPNQGRY
YEGYYAAGPGYGGRNDSDPTYGQQGHPNTWKREPGYTPPGAGNQNPPGMYPVTGPKKTYITDPVSAPCAPPLQPKGGHSGQLGPSSVAPS
FRPEDELEHLTKKMLYDMENPPADEYFGRCARCGENVVGEGTGCTAMDQVFHVDCFTCIICNNKLRGQPFYAVEKKAYCEPCYINTLEQC
NVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHC

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MECOM-LPP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneMECOMchr3:169381124chr3:188242453ENST00000264674-117189_44001117.0MAPK9%2C SMAD3 and probably SUV39H1
HgeneMECOMchr3:169381124chr3:188242453ENST00000392736-116189_44001052.0MAPK9%2C SMAD3 and probably SUV39H1
HgeneMECOMchr3:169381124chr3:188242453ENST00000433243-117189_44001053.0MAPK9%2C SMAD3 and probably SUV39H1
HgeneMECOMchr3:169381124chr3:188242453ENST00000464456-115189_44001043.0MAPK9%2C SMAD3 and probably SUV39H1
HgeneMECOMchr3:169381124chr3:188242453ENST00000468789-116189_44001052.0MAPK9%2C SMAD3 and probably SUV39H1
HgeneMECOMchr3:169381124chr3:188242453ENST00000472280-116189_44001053.0MAPK9%2C SMAD3 and probably SUV39H1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MECOM-LPP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MECOM-LPP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource