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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MED10-KIF21A (FusionGDB2 ID:52530)

Fusion Gene Summary for MED10-KIF21A

check button Fusion gene summary
Fusion gene informationFusion gene name: MED10-KIF21A
Fusion gene ID: 52530
HgeneTgene
Gene symbol

MED10

KIF21A

Gene ID

84246

55605

Gene namemediator complex subunit 10kinesin family member 21A
SynonymsL6|NUT2|TRG20CFEOM1|FEOM1|FEOM3A
Cytomap

5p15.31

12q12

Type of geneprotein-codingprotein-coding
Descriptionmediator of RNA polymerase II transcription subunit 10TRG-17TRG-20mediator of RNA polymerase II transcription, subunit 10transformation-related gene 17 proteintransformation-related gene 20 proteinkinesin-like protein KIF21Akinesin-like protein KIF2renal carcinoma antigen NY-REN-62
Modification date2020031320200313
UniProtAcc

Q9BTT4

Q7Z4S6

Ensembl transtripts involved in fusion geneENST00000255764, ENST00000547745, 
ENST00000361418, ENST00000361961, 
ENST00000395670, ENST00000541463, 
ENST00000544797, 
Fusion gene scores* DoF score4 X 4 X 2=328 X 7 X 5=280
# samples 48
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MED10 [Title/Abstract] AND KIF21A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMED10(6377279)-KIF21A(39752175), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MED10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KIF21A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A3XS-01AMED10chr5

6377279

-KIF21Achr12

39752175

-


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Fusion Gene ORF analysis for MED10-KIF21A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000255764ENST00000547745MED10chr5

6377279

-KIF21Achr12

39752175

-
In-frameENST00000255764ENST00000361418MED10chr5

6377279

-KIF21Achr12

39752175

-
In-frameENST00000255764ENST00000361961MED10chr5

6377279

-KIF21Achr12

39752175

-
In-frameENST00000255764ENST00000395670MED10chr5

6377279

-KIF21Achr12

39752175

-
In-frameENST00000255764ENST00000541463MED10chr5

6377279

-KIF21Achr12

39752175

-
In-frameENST00000255764ENST00000544797MED10chr5

6377279

-KIF21Achr12

39752175

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000255764MED10chr56377279-ENST00000361961KIF21Achr1239752175-547931711142831390
ENST00000255764MED10chr56377279-ENST00000395670KIF21Achr1239752175-552131711143251404
ENST00000255764MED10chr56377279-ENST00000544797KIF21Achr1239752175-424931711142111366
ENST00000255764MED10chr56377279-ENST00000361418KIF21Achr1239752175-432631711143221403
ENST00000255764MED10chr56377279-ENST00000541463KIF21Achr1239752175-416431711141631350

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000255764ENST00000361961MED10chr56377279-KIF21Achr1239752175-0.0004345790.9995654
ENST00000255764ENST00000395670MED10chr56377279-KIF21Achr1239752175-0.0003273940.99967265
ENST00000255764ENST00000544797MED10chr56377279-KIF21Achr1239752175-0.0023082020.99769187
ENST00000255764ENST00000361418MED10chr56377279-KIF21Achr1239752175-0.0016284220.99837166
ENST00000255764ENST00000541463MED10chr56377279-KIF21Achr1239752175-0.0017202770.9982797

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Fusion Genomic Features for MED10-KIF21A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MED10-KIF21A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:6377279/chr12:39752175)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MED10

Q9BTT4

KIF21A

Q7Z4S6

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.FUNCTION: Microtubule-binding motor protein probably involved in neuronal axonal transport. In vitro, has a plus-end directed motor activity (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneKIF21Achr5:6377279chr12:39752175ENST000003614186381053_10833391675.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST00000361418638365_5753391675.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST00000361418638931_10193391675.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST000003619616371053_10833391662.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST00000361961637365_5753391662.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST00000361961637931_10193391662.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST000005414636341053_10833391622.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST00000541463634365_5753391622.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST00000541463634931_10193391622.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST000005447976341053_10833391638.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST00000544797634365_5753391638.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST00000544797634931_10193391638.0Coiled coilOntology_term=ECO:0000255
TgeneKIF21Achr5:6377279chr12:39752175ENST000003614186381345_13823391675.0RepeatNote=WD 1
TgeneKIF21Achr5:6377279chr12:39752175ENST000003614186381385_14233391675.0RepeatNote=WD 2
TgeneKIF21Achr5:6377279chr12:39752175ENST000003614186381449_14873391675.0RepeatNote=WD 3
TgeneKIF21Achr5:6377279chr12:39752175ENST000003614186381490_15323391675.0RepeatNote=WD 4
TgeneKIF21Achr5:6377279chr12:39752175ENST000003614186381541_15783391675.0RepeatNote=WD 5
TgeneKIF21Achr5:6377279chr12:39752175ENST000003614186381582_16213391675.0RepeatNote=WD 6
TgeneKIF21Achr5:6377279chr12:39752175ENST000003614186381624_16613391675.0RepeatNote=WD 7
TgeneKIF21Achr5:6377279chr12:39752175ENST000003619616371345_13823391662.0RepeatNote=WD 1
TgeneKIF21Achr5:6377279chr12:39752175ENST000003619616371385_14233391662.0RepeatNote=WD 2
TgeneKIF21Achr5:6377279chr12:39752175ENST000003619616371449_14873391662.0RepeatNote=WD 3
TgeneKIF21Achr5:6377279chr12:39752175ENST000003619616371490_15323391662.0RepeatNote=WD 4
TgeneKIF21Achr5:6377279chr12:39752175ENST000003619616371541_15783391662.0RepeatNote=WD 5
TgeneKIF21Achr5:6377279chr12:39752175ENST000003619616371582_16213391662.0RepeatNote=WD 6
TgeneKIF21Achr5:6377279chr12:39752175ENST000003619616371624_16613391662.0RepeatNote=WD 7
TgeneKIF21Achr5:6377279chr12:39752175ENST000005414636341345_13823391622.0RepeatNote=WD 1
TgeneKIF21Achr5:6377279chr12:39752175ENST000005414636341385_14233391622.0RepeatNote=WD 2
TgeneKIF21Achr5:6377279chr12:39752175ENST000005414636341449_14873391622.0RepeatNote=WD 3
TgeneKIF21Achr5:6377279chr12:39752175ENST000005414636341490_15323391622.0RepeatNote=WD 4
TgeneKIF21Achr5:6377279chr12:39752175ENST000005414636341541_15783391622.0RepeatNote=WD 5
TgeneKIF21Achr5:6377279chr12:39752175ENST000005414636341582_16213391622.0RepeatNote=WD 6
TgeneKIF21Achr5:6377279chr12:39752175ENST000005414636341624_16613391622.0RepeatNote=WD 7
TgeneKIF21Achr5:6377279chr12:39752175ENST000005447976341345_13823391638.0RepeatNote=WD 1
TgeneKIF21Achr5:6377279chr12:39752175ENST000005447976341385_14233391638.0RepeatNote=WD 2
TgeneKIF21Achr5:6377279chr12:39752175ENST000005447976341449_14873391638.0RepeatNote=WD 3
TgeneKIF21Achr5:6377279chr12:39752175ENST000005447976341490_15323391638.0RepeatNote=WD 4
TgeneKIF21Achr5:6377279chr12:39752175ENST000005447976341541_15783391638.0RepeatNote=WD 5
TgeneKIF21Achr5:6377279chr12:39752175ENST000005447976341582_16213391638.0RepeatNote=WD 6
TgeneKIF21Achr5:6377279chr12:39752175ENST000005447976341624_16613391638.0RepeatNote=WD 7

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneKIF21Achr5:6377279chr12:39752175ENST000003614186389_3713391675.0DomainKinesin motor
TgeneKIF21Achr5:6377279chr12:39752175ENST000003619616379_3713391662.0DomainKinesin motor
TgeneKIF21Achr5:6377279chr12:39752175ENST000005414636349_3713391622.0DomainKinesin motor
TgeneKIF21Achr5:6377279chr12:39752175ENST000005447976349_3713391638.0DomainKinesin motor
TgeneKIF21Achr5:6377279chr12:39752175ENST0000036141863888_953391675.0Nucleotide bindingATP
TgeneKIF21Achr5:6377279chr12:39752175ENST0000036196163788_953391662.0Nucleotide bindingATP
TgeneKIF21Achr5:6377279chr12:39752175ENST0000054146363488_953391622.0Nucleotide bindingATP
TgeneKIF21Achr5:6377279chr12:39752175ENST0000054479763488_953391638.0Nucleotide bindingATP


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Fusion Gene Sequence for MED10-KIF21A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>52530_52530_1_MED10-KIF21A_MED10_chr5_6377279_ENST00000255764_KIF21A_chr12_39752175_ENST00000361418_length(transcript)=4326nt_BP=317nt
CAGAGGAAACGGAAGTCGTATCTGTCCGGACGGAAGCAGGAAGCGGGAGCGTAGGGCCACGCCTGCGGCGCTGCTGGTTGAGGCTGTGTG
GGTCGGGGACGGGCCGAGGCGATGGCGGAGAAGTTTGACCACCTAGAGGAGCACCTGGAGAAGTTCGTGGAGAACATTCGGCAGCTCGGC
ATCATCGTCAGTGACTTCCAGCCCAGCAGCCAGGCCGGGCTCAACCAAAAGCTGAATTTTATTGTTACTGGCTTACAGGATATTGACAAG
TGCAGACAGCAGCTTCATGATATTACTGTACCGTTAGAAGTTTTTGACCAAACAATCATGATAGCATGTGTCAGCCCTTCAGACAGAGAC
TTTATGGAAACGTTAAACACCCTGAAATACGCCAATCGAGCTAGAAATATCAAGAATAAGGTGATGGTCAATCAGGACAGAGCTAGTCAG
CAAATCAATGCACTTCGTAGTGAAATCACACGACTTCAGATGGAGCTCATGGAGTACAAAACAGGTAAAAGAATAATTGACGAAGAGGGT
GTGGAAAGCATCAATGACATGTTTCATGAGAATGCTATGCTACAGACTGAAAATAATAACCTGCGTGTAAGAATTAAAGCCATGCAAGAG
ACGGTTGATGCATTGAGGTCCAGAATTACACAGCTTGTTAGTGATCAGGCCAACCATGTTCTTGCCAGAGCAGGTGAAGGAAATGAGGAG
ATTAGTAATATGATTCATAGTTATATAAAAGAAATCGAAGATCTCAGGGCAAAATTATTAGAAAGTGAAGCAGTGAATGAGAACCTTCGA
AAAAACTTGACAAGAGCCACAGCAAGAGCGCCATATTTCAGCGGATCATCAACTTTTTCTCCTACCATACTATCCTCAGACAAAGAAACC
ATTGAAATTATAGACCTAGCAAAAAAAGATTTAGAGAAGTTGAAAAGAAAAGAAAAGAGGAAGAAAAAAAGGCTACAGAAACTTGAGGAA
AGCAATCGAGAAGAAAGAAGTGTGGCTGGTAAAGAGGATAATACAGACACTGACCAAGAGAAGAAAGAAGAAAAGGGTGTTTCGGAAAGA
GAAAACAATGAATTAGAAGTGGAAGAAAGTCAAGAAGTGAGTGATCATGAGGATGAAGAAGAGGAGGAGGAGGAGGAGGAAGATGACATT
GATGGGGGTGAAAGTTCTGATGAATCAGATTCTGAATCAGATGAAAAAGCCAATTATCAAGCAGACTTGGCAAACATTACTTGTGAAATT
GCAATTAAGCAAAAGCTGATTGATGAACTAGAAAACAGCCAGAAAAGACTGCAGACTCTGAAAAAGCAGTATGAAGAGAAGCTAATGATG
CTGCAACATAAAATTCGGGATACTCAGCTTGAAAGAGACCAGGTGCTTCAAAACTTAGGCTCGGTAGAATCTTACTCAGAAGAAAAAGCA
AAAAAAGTTAGGTCTGAATATGAAAAGAAACTCCAAGCCATGAACAAAGAACTGCAGAGACTTCAAGCAGCTCAAAAAGAACATGCAAGG
TTGCTTAAAAATCAGTCTCAGTATGAAAAGCAATTGAAGAAATTGCAGCAGGATGTGATGGAAATGAAAAAAACAAAGGTTCGCCTAATG
AAACAAATGAAAGAAGAACAAGAGAAAGCCAGACTGACTGAGTCTAGAAGAAACAGAGAGATTGCTCAGTTGAAAAAGGATCAACGTAAA
AGAGATCATCAACTTAGACTTCTGGAAGCCCAAAAAAGAAACCAAGAAGTGGTTCTACGTCGCAAAACTGAAGAGGTTACGGCTCTTCGT
CGGCAAGTAAGACCCATGTCAGATAAAGTGGCTGGGAAAGTTACTCGGAAGCTGAGTTCATCTGATGCACCTGCTCAGGACACAGGTTCC
AGTGCAGCTGCTGTCGAAACAGATGCATCAAGGACAGGAGCCCAGCAGAAAATGAGAATTCCTGTGGCGAGAGTCCAGGCCTTACCAACG
CCGGCAACAAATGGAAACAGGAAAAAATATCAGAGGAAAGGATTGACTGGCCGAGTGTTTATTTCCAAGACAGCTCGCATGAAGTGGCAG
CTCCTTGAGCGCAGGGTCACAGACATCATCATGCAGAAGATGACCATTTCCAACATGGAGGCAGATATGAATAGACTCCTCAAGCAACGG
GAGGAACTCACAAAAAGACGAGAGAAACTTTCAAAAAGAAGGGAGAAGATAGTCAAGGAGAATGGAGAGGGAGATAAAAATGTGGCTAAT
ATCAATGAAGAGATGGAGTCACTGACTGCTAATATCGATTACATCAATGACAGTATTTCTGATTGTCAGGCCAACATAATGCAGATGGAA
GAAGCAAAGGAAGAAGGTGAGACATTGGATGTTACTGCAGTCATTAATGCCTGCACCCTTACAGAAGCCCGATACCTGCTAGATCACTTC
CTGTCAATGGGCATCAATAAGGGTCTTCAGGCTGCCCAGAAAGAGGCTCAAATTAAAGTACTGGAAGGTCGACTCAAACAAACAGAAATA
ACCAGTGCTACCCAAAACCAGCTCTTATTCCATATGTTGAAAGAGAAGGCAGAATTAAATCCTGAGCTAGATGCTTTACTAGGCCATGCT
TTACAAGATCTAGATAGCGTACCATTAGAAAATGTAGAGGATAGTACTGATGAGGATGCTCCTTTAAACAGCCCAGGATCAGAAGGAAGC
ACGCTGTCTTCAGATCTCATGAAGCTTTGTGGTGAAGTGAAACCTAAGAACAAGGCCCGAAGGAGAACCACCACTCAGATGGAATTGCTG
TATGCAGATAGCAGTGAACTAGCTTCAGACACTAGTACAGGAGATGCCTCCTTGCCTGGCCCTCTCACACCTGTTGCAGAAGGGCAAGAG
ATTGGAATGAATACAGAGACAAGTGGTACTTCTGCTAGGGAAAAAGAGCTCTCTCCCCCACCTGGCTTACCTTCTAAGATAGGCAGCATT
TCCAGGCAGTCATCTCTATCAGAAAAAAAAATTCCAGAGCCTTCTCCTGTAACAAGGAGAAAGGCATATGAGAAAGCAGAAAAATCAAAG
GCCAAGGAACAAAAGCACTCAGATTCTGGAACTTCAGAGGCTAGTCTTTCACCTCCTTCTTCCCCACCAAGCCGGCCCCGTAATGAACTG
AATGTTTTTAATCGTCTTACTGTTTCTCAGGGAAACACATCAGTTCAGCAGGATAAGTCTGATGAAAGTGACTCCTCTCTCTCGGAGGTA
CACAGATCCTCCAGAAGGGGCATAATCAACCCATTTCCTGCTTCAAAAGGAATCAGAGCTTTTCCACTTCAGTGTATTCACATAGCTGAA
GGGCATACAAAAGCTGTGCTCTGTGTGGATTCTACTGATGATCTCCTCTTCACTGGATCAAAAGATCGTACTTGTAAAGTATGGAATCTG
GTGACTGGGCAGGAAATAATGTCACTGGGGGGTCATCCCAACAATGTCGTGTCTGTAAAATACTGTAATTATACCAGTTTGGTCTTCACT
GTATCAACATCTTATATTAAGGTGTGGGATATCAGAGATTCAGCAAAGTGCATTCGAACACTAACGTCTTCAGGTCAAGTTACTCTTGGA
GATGCTTGTTCTGCAAGTACCAGTCGAACAGTAGCTATTCCTTCTGGAGAGAACCAGATCAATCAAATTGCCCTAAACCCAACTGGCACC
TTCCTCTATGCTGCTTCTGGAAATGCTGTCAGGATGTGGGATCTTAAAAGGTTTCAGTCTACAGGAAAGTTAACAGGACACCTAGGCCCT
GTTATGTGCCTTACTGTGGATCAGATTTCCAGTGGACAAGATCTAATCATCACTGGCTCCAAGGATCATTACATCAAAATGTTTGATGTT
ACAGAAGGAGCTCTTGGGACTGTGAGTCCCACCCACAATTTTGAACCCCCTCATTATGATGGCATAGAAGCACTAACCATTCAAGGGGAT
AACCTATTTAGTGGGTCTAGAGATAATGGAATCAAGAAATGGGACTTAACTCAAAAAGACCTTCTTCAGCAAGTTCCAAATGCACATAAG
GATTGGGTCTGTGCCCTGGGAGTGGTGCCAGACCACCCAGTTTTGCTCAGTGGCTGCAGAGGGGGCATTTTGAAAGTCTGGAACATGGAT
ACTTTTATGCCAGTGGGAGAGATGAAGGGTCATGATAGTCCTATCAATGCCATATGTGTTAATTCCACCCACATTTTTACTGCAGCTGAT
GATCGAACTGTGAGAATTTGGAAGGCTCGCAATTTGCAAGATGGTCAGATCTCTGACACAGGAGATCTGGGGGAAGATATTGCCAGTAAT

>52530_52530_1_MED10-KIF21A_MED10_chr5_6377279_ENST00000255764_KIF21A_chr12_39752175_ENST00000361418_length(amino acids)=1403AA_BP=67
MAEKFDHLEEHLEKFVENIRQLGIIVSDFQPSSQAGLNQKLNFIVTGLQDIDKCRQQLHDITVPLEVFDQTIMIACVSPSDRDFMETLNT
LKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRS
RITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLA
KKDLEKLKRKEKRKKKRLQKLEESNREERSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSD
ESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEY
EKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRL
LEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNR
KKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMES
LTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQ
LLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSEL
ASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHS
DSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIRAFPLQCIHIAEGHTKAVL
CVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSAST
SRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHYIKMFDVTEGALGT
VSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGE

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>52530_52530_2_MED10-KIF21A_MED10_chr5_6377279_ENST00000255764_KIF21A_chr12_39752175_ENST00000361961_length(transcript)=5479nt_BP=317nt
CAGAGGAAACGGAAGTCGTATCTGTCCGGACGGAAGCAGGAAGCGGGAGCGTAGGGCCACGCCTGCGGCGCTGCTGGTTGAGGCTGTGTG
GGTCGGGGACGGGCCGAGGCGATGGCGGAGAAGTTTGACCACCTAGAGGAGCACCTGGAGAAGTTCGTGGAGAACATTCGGCAGCTCGGC
ATCATCGTCAGTGACTTCCAGCCCAGCAGCCAGGCCGGGCTCAACCAAAAGCTGAATTTTATTGTTACTGGCTTACAGGATATTGACAAG
TGCAGACAGCAGCTTCATGATATTACTGTACCGTTAGAAGTTTTTGACCAAACAATCATGATAGCATGTGTCAGCCCTTCAGACAGAGAC
TTTATGGAAACGTTAAACACCCTGAAATACGCCAATCGAGCTAGAAATATCAAGAATAAGGTGATGGTCAATCAGGACAGAGCTAGTCAG
CAAATCAATGCACTTCGTAGTGAAATCACACGACTTCAGATGGAGCTCATGGAGTACAAAACAGGTAAAAGAATAATTGACGAAGAGGGT
GTGGAAAGCATCAATGACATGTTTCATGAGAATGCTATGCTACAGACTGAAAATAATAACCTGCGTGTAAGAATTAAAGCCATGCAAGAG
ACGGTTGATGCATTGAGGTCCAGAATTACACAGCTTGTTAGTGATCAGGCCAACCATGTTCTTGCCAGAGCAGGTGAAGGAAATGAGGAG
ATTAGTAATATGATTCATAGTTATATAAAAGAAATCGAAGATCTCAGGGCAAAATTATTAGAAAGTGAAGCAGTGAATGAGAACCTTCGA
AAAAACTTGACAAGAGCCACAGCAAGAGCGCCATATTTCAGCGGATCATCAACTTTTTCTCCTACCATACTATCCTCAGACAAAGAAACC
ATTGAAATTATAGACCTAGCAAAAAAAGATTTAGAGAAGTTGAAAAGAAAAGAAAAGAGGAAGAAAAAAAGTGTGGCTGGTAAAGAGGAT
AATACAGACACTGACCAAGAGAAGAAAGAAGAAAAGGGTGTTTCGGAAAGAGAAAACAATGAATTAGAAGTGGAAGAAAGTCAAGAAGTG
AGTGATCATGAGGATGAAGAAGAGGAGGAGGAGGAGGAGGAAGATGACATTGATGGGGGTGAAAGTTCTGATGAATCAGATTCTGAATCA
GATGAAAAAGCCAATTATCAAGCAGACTTGGCAAACATTACTTGTGAAATTGCAATTAAGCAAAAGCTGATTGATGAACTAGAAAACAGC
CAGAAAAGACTGCAGACTCTGAAAAAGCAGTATGAAGAGAAGCTAATGATGCTGCAACATAAAATTCGGGATACTCAGCTTGAAAGAGAC
CAGGTGCTTCAAAACTTAGGCTCGGTAGAATCTTACTCAGAAGAAAAAGCAAAAAAAGTTAGGTCTGAATATGAAAAGAAACTCCAAGCC
ATGAACAAAGAACTGCAGAGACTTCAAGCAGCTCAAAAAGAACATGCAAGGTTGCTTAAAAATCAGTCTCAGTATGAAAAGCAATTGAAG
AAATTGCAGCAGGATGTGATGGAAATGAAAAAAACAAAGGTTCGCCTAATGAAACAAATGAAAGAAGAACAAGAGAAAGCCAGACTGACT
GAGTCTAGAAGAAACAGAGAGATTGCTCAGTTGAAAAAGGATCAACGTAAAAGAGATCATCAACTTAGACTTCTGGAAGCCCAAAAAAGA
AACCAAGAAGTGGTTCTACGTCGCAAAACTGAAGAGGTTACGGCTCTTCGTCGGCAAGTAAGACCCATGTCAGATAAAGTGGCTGGGAAA
GTTACTCGGAAGCTGAGTTCATCTGATGCACCTGCTCAGGACACAGGTTCCAGTGCAGCTGCTGTCGAAACAGATGCATCAAGGACAGGA
GCCCAGCAGAAAATGAGAATTCCTGTGGCGAGAGTCCAGGCCTTACCAACGCCGGCAACAAATGGAAACAGGAAAAAATATCAGAGGAAA
GGATTGACTGGCCGAGTGTTTATTTCCAAGACAGCTCGCATGAAGTGGCAGCTCCTTGAGCGCAGGGTCACAGACATCATCATGCAGAAG
ATGACCATTTCCAACATGGAGGCAGATATGAATAGACTCCTCAAGCAACGGGAGGAACTCACAAAAAGACGAGAGAAACTTTCAAAAAGA
AGGGAGAAGATAGTCAAGGAGAATGGAGAGGGAGATAAAAATGTGGCTAATATCAATGAAGAGATGGAGTCACTGACTGCTAATATCGAT
TACATCAATGACAGTATTTCTGATTGTCAGGCCAACATAATGCAGATGGAAGAAGCAAAGGAAGAAGGTGAGACATTGGATGTTACTGCA
GTCATTAATGCCTGCACCCTTACAGAAGCCCGATACCTGCTAGATCACTTCCTGTCAATGGGCATCAATAAGGGTCTTCAGGCTGCCCAG
AAAGAGGCTCAAATTAAAGTACTGGAAGGTCGACTCAAACAAACAGAAATAACCAGTGCTACCCAAAACCAGCTCTTATTCCATATGTTG
AAAGAGAAGGCAGAATTAAATCCTGAGCTAGATGCTTTACTAGGCCATGCTTTACAAGATCTAGATAGCGTACCATTAGAAAATGTAGAG
GATAGTACTGATGAGGATGCTCCTTTAAACAGCCCAGGATCAGAAGGAAGCACGCTGTCTTCAGATCTCATGAAGCTTTGTGGTGAAGTG
AAACCTAAGAACAAGGCCCGAAGGAGAACCACCACTCAGATGGAATTGCTGTATGCAGATAGCAGTGAACTAGCTTCAGACACTAGTACA
GGAGATGCCTCCTTGCCTGGCCCTCTCACACCTGTTGCAGAAGGGCAAGAGATTGGAATGAATACAGAGACAAGTGGTACTTCTGCTAGG
GAAAAAGAGCTCTCTCCCCCACCTGGCTTACCTTCTAAGATAGGCAGCATTTCCAGGCAGTCATCTCTATCAGAAAAAAAAATTCCAGAG
CCTTCTCCTGTAACAAGGAGAAAGGCATATGAGAAAGCAGAAAAATCAAAGGCCAAGGAACAAAAGCACTCAGATTCTGGAACTTCAGAG
GCTAGTCTTTCACCTCCTTCTTCCCCACCAAGCCGGCCCCGTAATGAACTGAATGTTTTTAATCGTCTTACTGTTTCTCAGGGAAACACA
TCAGTTCAGCAGGATAAGTCTGATGAAAGTGACTCCTCTCTCTCGGAGGTACACAGATCCTCCAGAAGGGGCATAATCAACCCATTTCCT
GCTTCAAAAGGAATCAGAGCTTTTCCACTTCAGTGTATTCACATAGCTGAAGGGCATACAAAAGCTGTGCTCTGTGTGGATTCTACTGAT
GATCTCCTCTTCACTGGATCAAAAGATCGTACTTGTAAAGTATGGAATCTGGTGACTGGGCAGGAAATAATGTCACTGGGGGGTCATCCC
AACAATGTCGTGTCTGTAAAATACTGTAATTATACCAGTTTGGTCTTCACTGTATCAACATCTTATATTAAGGTGTGGGATATCAGAGAT
TCAGCAAAGTGCATTCGAACACTAACGTCTTCAGGTCAAGTTACTCTTGGAGATGCTTGTTCTGCAAGTACCAGTCGAACAGTAGCTATT
CCTTCTGGAGAGAACCAGATCAATCAAATTGCCCTAAACCCAACTGGCACCTTCCTCTATGCTGCTTCTGGAAATGCTGTCAGGATGTGG
GATCTTAAAAGGTTTCAGTCTACAGGAAAGTTAACAGGACACCTAGGCCCTGTTATGTGCCTTACTGTGGATCAGATTTCCAGTGGACAA
GATCTAATCATCACTGGCTCCAAGGATCATTACATCAAAATGTTTGATGTTACAGAAGGAGCTCTTGGGACTGTGAGTCCCACCCACAAT
TTTGAACCCCCTCATTATGATGGCATAGAAGCACTAACCATTCAAGGGGATAACCTATTTAGTGGGTCTAGAGATAATGGAATCAAGAAA
TGGGACTTAACTCAAAAAGACCTTCTTCAGCAAGTTCCAAATGCACATAAGGATTGGGTCTGTGCCCTGGGAGTGGTGCCAGACCACCCA
GTTTTGCTCAGTGGCTGCAGAGGGGGCATTTTGAAAGTCTGGAACATGGATACTTTTATGCCAGTGGGAGAGATGAAGGGTCATGATAGT
CCTATCAATGCCATATGTGTTAATTCCACCCACATTTTTACTGCAGCTGATGATCGAACTGTGAGAATTTGGAAGGCTCGCAATTTGCAA
GATGGTCAGATCTCTGACACAGGAGATCTGGGGGAAGATATTGCCAGTAATTAAACATGAATGAAGATAGGTTGTAAACTGAATGCTGTG
ATAATACTCTGTATTCTTTATGGAAAATGTTGTCCTGTACTTACTAGGCAAAACGTATGAATCGGATTAACTGGAAAATATATCTGAATT
CAACTGCTGACTATAAATGGTATTCTAATAAAATTGTGTACTATCCTGTGTGCTTAGTTTTAAGATCAACCAATAGATATATATCCTACA
ATTGATATATTGCTTTATTCACACTTTTATTGTGGCTGAATTTTTGTGCCTATCTATAAAACACACTTTCAAATTATTTGAATTACCAAG
ACGTCTGCTTTTGTGACAGTCAGAAAACACACCTGGAATACGATGCAGCCCACCATTAACTCATTCATGTAGTTTATTCAAGTGATTTAT
GTATTTAAACTAAATATTGAAAATGTTAGTCAAATTGTGGTTTGCTTGTCAGGTATTTATATCAGTCTGTAGTGGATTCCCAAATTTCAA
AGCTCTTTTAATGTAATGGACAAAAATAAGATATGAGAATATTATTGATGAATTTTCATAAGGTGGAATTGATCTTAATCTACTAACAGA
GAAGGGTAGACAGTTTGTGTTAAATGTTGGCATTTACTTGTATTGACCAAAGTTTTGCAGCTCTACTATATTCTGTGCTCAGGACTAAAA
TGCTGTTAATTTTTTTTTTTTTTTCCAGTGCTGTGCATATATTCTGTGATGGGAAACATTGTTGATGTCCTAACAGAAATATATTTTGAT
CTATTTTCCTATGGAGTTGTTTCTATTATGACCATTTAATTTTGTTTTTATTTAATAGTAGTATTTCCTTCCCTTTTATCTAATTTTTTA
TATGCTGCTAAATATATTTTAAATATACTATGTTTGCGAACCTTGGTAGCTATGATGAGAGCTATTATCATCTGTGGTGGGAAAAGCTAT
GTAAATAGGTAGATTGTATAGAGAGACTATCTTGTGTTGTGCCTGTATGAATTTTTAAAAGTTGTTGACTGGATTTTGCAAAAGGATGTA
TAATATTTCTGTCTGCTCAGAATATTAATTTGTAAATTCTGCAAGTTTAATTTTTATGTAGATGGTATAACATTTGAAAATATTGTCTTA

>52530_52530_2_MED10-KIF21A_MED10_chr5_6377279_ENST00000255764_KIF21A_chr12_39752175_ENST00000361961_length(amino acids)=1390AA_BP=67
MAEKFDHLEEHLEKFVENIRQLGIIVSDFQPSSQAGLNQKLNFIVTGLQDIDKCRQQLHDITVPLEVFDQTIMIACVSPSDRDFMETLNT
LKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRS
RITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLA
KKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQ
ADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQR
LQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLR
RKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVF
ISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSIS
DCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELN
PELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPG
PLTPVAEGQEIGMNTETSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPPS
SPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGS
KDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQI
NQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYD
GIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAICV

--------------------------------------------------------------
>52530_52530_3_MED10-KIF21A_MED10_chr5_6377279_ENST00000255764_KIF21A_chr12_39752175_ENST00000395670_length(transcript)=5521nt_BP=317nt
CAGAGGAAACGGAAGTCGTATCTGTCCGGACGGAAGCAGGAAGCGGGAGCGTAGGGCCACGCCTGCGGCGCTGCTGGTTGAGGCTGTGTG
GGTCGGGGACGGGCCGAGGCGATGGCGGAGAAGTTTGACCACCTAGAGGAGCACCTGGAGAAGTTCGTGGAGAACATTCGGCAGCTCGGC
ATCATCGTCAGTGACTTCCAGCCCAGCAGCCAGGCCGGGCTCAACCAAAAGCTGAATTTTATTGTTACTGGCTTACAGGATATTGACAAG
TGCAGACAGCAGCTTCATGATATTACTGTACCGTTAGAAGTTTTTGACCAAACAATCATGATAGCATGTGTCAGCCCTTCAGACAGAGAC
TTTATGGAAACGTTAAACACCCTGAAATACGCCAATCGAGCTAGAAATATCAAGAATAAGGTGATGGTCAATCAGGACAGAGCTAGTCAG
CAAATCAATGCACTTCGTAGTGAAATCACACGACTTCAGATGGAGCTCATGGAGTACAAAACAGGTAAAAGAATAATTGACGAAGAGGGT
GTGGAAAGCATCAATGACATGTTTCATGAGAATGCTATGCTACAGACTGAAAATAATAACCTGCGTGTAAGAATTAAAGCCATGCAAGAG
ACGGTTGATGCATTGAGGTCCAGAATTACACAGCTTGTTAGTGATCAGGCCAACCATGTTCTTGCCAGAGCAGGTGAAGGAAATGAGGAG
ATTAGTAATATGATTCATAGTTATATAAAAGAAATCGAAGATCTCAGGGCAAAATTATTAGAAAGTGAAGCAGTGAATGAGAACCTTCGA
AAAAACTTGACAAGAGCCACAGCAAGAGCGCCATATTTCAGCGGATCATCAACTTTTTCTCCTACCATACTATCCTCAGACAAAGAAACC
ATTGAAATTATAGACCTAGCAAAAAAAGATTTAGAGAAGTTGAAAAGAAAAGAAAAGAGGAAGAAAAAAAGGCTACAGAAACTTGAGGAA
AGCAATCGAGAAGAAAGAAGTGTGGCTGGTAAAGAGGATAATACAGACACTGACCAAGAGAAGAAAGAAGAAAAGGGTGTTTCGGAAAGA
GAAAACAATGAATTAGAAGTGGAAGAAAGTCAAGAAGTGAGTGATCATGAGGATGAAGAAGAGGAGGAGGAGGAGGAGGAAGATGACATT
GATGGGGGTGAAAGTTCTGATGAATCAGATTCTGAATCAGATGAAAAAGCCAATTATCAAGCAGACTTGGCAAACATTACTTGTGAAATT
GCAATTAAGCAAAAGCTGATTGATGAACTAGAAAACAGCCAGAAAAGACTGCAGACTCTGAAAAAGCAGTATGAAGAGAAGCTAATGATG
CTGCAACATAAAATTCGGGATACTCAGCTTGAAAGAGACCAGGTGCTTCAAAACTTAGGCTCGGTAGAATCTTACTCAGAAGAAAAAGCA
AAAAAAGTTAGGTCTGAATATGAAAAGAAACTCCAAGCCATGAACAAAGAACTGCAGAGACTTCAAGCAGCTCAAAAAGAACATGCAAGG
TTGCTTAAAAATCAGTCTCAGTATGAAAAGCAATTGAAGAAATTGCAGCAGGATGTGATGGAAATGAAAAAAACAAAGGTTCGCCTAATG
AAACAAATGAAAGAAGAACAAGAGAAAGCCAGACTGACTGAGTCTAGAAGAAACAGAGAGATTGCTCAGTTGAAAAAGGATCAACGTAAA
AGAGATCATCAACTTAGACTTCTGGAAGCCCAAAAAAGAAACCAAGAAGTGGTTCTACGTCGCAAAACTGAAGAGGTTACGGCTCTTCGT
CGGCAAGTAAGACCCATGTCAGATAAAGTGGCTGGGAAAGTTACTCGGAAGCTGAGTTCATCTGATGCACCTGCTCAGGACACAGGTTCC
AGTGCAGCTGCTGTCGAAACAGATGCATCAAGGACAGGAGCCCAGCAGAAAATGAGAATTCCTGTGGCGAGAGTCCAGGCCTTACCAACG
CCGGCAACAAATGGAAACAGGAAAAAATATCAGAGGAAAGGATTGACTGGCCGAGTGTTTATTTCCAAGACAGCTCGCATGAAGTGGCAG
CTCCTTGAGCGCAGGGTCACAGACATCATCATGCAGAAGATGACCATTTCCAACATGGAGGCAGATATGAATAGACTCCTCAAGCAACGG
GAGGAACTCACAAAAAGACGAGAGAAACTTTCAAAAAGAAGGGAGAAGATAGTCAAGGAGAATGGAGAGGGAGATAAAAATGTGGCTAAT
ATCAATGAAGAGATGGAGTCACTGACTGCTAATATCGATTACATCAATGACAGTATTTCTGATTGTCAGGCCAACATAATGCAGATGGAA
GAAGCAAAGGAAGAAGGTGAGACATTGGATGTTACTGCAGTCATTAATGCCTGCACCCTTACAGAAGCCCGATACCTGCTAGATCACTTC
CTGTCAATGGGCATCAATAAGGGTCTTCAGGCTGCCCAGAAAGAGGCTCAAATTAAAGTACTGGAAGGTCGACTCAAACAAACAGAAATA
ACCAGTGCTACCCAAAACCAGCTCTTATTCCATATGTTGAAAGAGAAGGCAGAATTAAATCCTGAGCTAGATGCTTTACTAGGCCATGCT
TTACAAGATTTTAAACATTTTTTTGTAGAAAATGTAGAGGATAGTACTGATGAGGATGCTCCTTTAAACAGCCCAGGATCAGAAGGAAGC
ACGCTGTCTTCAGATCTCATGAAGCTTTGTGGTGAAGTGAAACCTAAGAACAAGGCCCGAAGGAGAACCACCACTCAGATGGAATTGCTG
TATGCAGATAGCAGTGAACTAGCTTCAGACACTAGTACAGGAGATGCCTCCTTGCCTGGCCCTCTCACACCTGTTGCAGAAGGGCAAGAG
ATTGGAATGAATACAGAGACAAGTGGTACTTCTGCTAGGGAAAAAGAGCTCTCTCCCCCACCTGGCTTACCTTCTAAGATAGGCAGCATT
TCCAGGCAGTCATCTCTATCAGAAAAAAAAATTCCAGAGCCTTCTCCTGTAACAAGGAGAAAGGCATATGAGAAAGCAGAAAAATCAAAG
GCCAAGGAACAAAAGCACTCAGATTCTGGAACTTCAGAGGCTAGTCTTTCACCTCCTTCTTCCCCACCAAGCCGGCCCCGTAATGAACTG
AATGTTTTTAATCGTCTTACTGTTTCTCAGGGAAACACATCAGTTCAGCAGGATAAGTCTGATGAAAGTGACTCCTCTCTCTCGGAGGTA
CACAGAAATTCTAACCTTAGGGGCATAATCAACCCATTTCCTGCTTCAAAAGGAATCAGAGCTTTTCCACTTCAGTGTATTCACATAGCT
GAAGGGCATACAAAAGCTGTGCTCTGTGTGGATTCTACTGATGATCTCCTCTTCACTGGATCAAAAGATCGTACTTGTAAAGTATGGAAT
CTGGTGACTGGGCAGGAAATAATGTCACTGGGGGGTCATCCCAACAATGTCGTGTCTGTAAAATACTGTAATTATACCAGTTTGGTCTTC
ACTGTATCAACATCTTATATTAAGGTGTGGGATATCAGAGATTCAGCAAAGTGCATTCGAACACTAACGTCTTCAGGTCAAGTTACTCTT
GGAGATGCTTGTTCTGCAAGTACCAGTCGAACAGTAGCTATTCCTTCTGGAGAGAACCAGATCAATCAAATTGCCCTAAACCCAACTGGC
ACCTTCCTCTATGCTGCTTCTGGAAATGCTGTCAGGATGTGGGATCTTAAAAGGTTTCAGTCTACAGGAAAGTTAACAGGACACCTAGGC
CCTGTTATGTGCCTTACTGTGGATCAGATTTCCAGTGGACAAGATCTAATCATCACTGGCTCCAAGGATCATTACATCAAAATGTTTGAT
GTTACAGAAGGAGCTCTTGGGACTGTGAGTCCCACCCACAATTTTGAACCCCCTCATTATGATGGCATAGAAGCACTAACCATTCAAGGG
GATAACCTATTTAGTGGGTCTAGAGATAATGGAATCAAGAAATGGGACTTAACTCAAAAAGACCTTCTTCAGCAAGTTCCAAATGCACAT
AAGGATTGGGTCTGTGCCCTGGGAGTGGTGCCAGACCACCCAGTTTTGCTCAGTGGCTGCAGAGGGGGCATTTTGAAAGTCTGGAACATG
GATACTTTTATGCCAGTGGGAGAGATGAAGGGTCATGATAGTCCTATCAATGCCATATGTGTTAATTCCACCCACATTTTTACTGCAGCT
GATGATCGAACTGTGAGAATTTGGAAGGCTCGCAATTTGCAAGATGGTCAGATCTCTGACACAGGAGATCTGGGGGAAGATATTGCCAGT
AATTAAACATGAATGAAGATAGGTTGTAAACTGAATGCTGTGATAATACTCTGTATTCTTTATGGAAAATGTTGTCCTGTACTTACTAGG
CAAAACGTATGAATCGGATTAACTGGAAAATATATCTGAATTCAACTGCTGACTATAAATGGTATTCTAATAAAATTGTGTACTATCCTG
TGTGCTTAGTTTTAAGATCAACCAATAGATATATATCCTACAATTGATATATTGCTTTATTCACACTTTTATTGTGGCTGAATTTTTGTG
CCTATCTATAAAACACACTTTCAAATTATTTGAATTACCAAGACGTCTGCTTTTGTGACAGTCAGAAAACACACCTGGAATACGATGCAG
CCCACCATTAACTCATTCATGTAGTTTATTCAAGTGATTTATGTATTTAAACTAAATATTGAAAATGTTAGTCAAATTGTGGTTTGCTTG
TCAGGTATTTATATCAGTCTGTAGTGGATTCCCAAATTTCAAAGCTCTTTTAATGTAATGGACAAAAATAAGATATGAGAATATTATTGA
TGAATTTTCATAAGGTGGAATTGATCTTAATCTACTAACAGAGAAGGGTAGACAGTTTGTGTTAAATGTTGGCATTTACTTGTATTGACC
AAAGTTTTGCAGCTCTACTATATTCTGTGCTCAGGACTAAAATGCTGTTAATTTTTTTTTTTTTTTCCAGTGCTGTGCATATATTCTGTG
ATGGGAAACATTGTTGATGTCCTAACAGAAATATATTTTGATCTATTTTCCTATGGAGTTGTTTCTATTATGACCATTTAATTTTGTTTT
TATTTAATAGTAGTATTTCCTTCCCTTTTATCTAATTTTTTATATGCTGCTAAATATATTTTAAATATACTATGTTTGCGAACCTTGGTA
GCTATGATGAGAGCTATTATCATCTGTGGTGGGAAAAGCTATGTAAATAGGTAGATTGTATAGAGAGACTATCTTGTGTTGTGCCTGTAT
GAATTTTTAAAAGTTGTTGACTGGATTTTGCAAAAGGATGTATAATATTTCTGTCTGCTCAGAATATTAATTTGTAAATTCTGCAAGTTT
AATTTTTATGTAGATGGTATAACATTTGAAAATATTGTCTTATGTGATTTTTTCCCCTGAAAATATTTGCTTGTAAATGAAAACTTAGCT

>52530_52530_3_MED10-KIF21A_MED10_chr5_6377279_ENST00000255764_KIF21A_chr12_39752175_ENST00000395670_length(amino acids)=1404AA_BP=67
MAEKFDHLEEHLEKFVENIRQLGIIVSDFQPSSQAGLNQKLNFIVTGLQDIDKCRQQLHDITVPLEVFDQTIMIACVSPSDRDFMETLNT
LKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRS
RITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLA
KKDLEKLKRKEKRKKKRLQKLEESNREERSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSD
ESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEY
EKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRL
LEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNR
KKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMES
LTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQ
LLFHMLKEKAELNPELDALLGHALQDFKHFFVENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSEL
ASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHS
DSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRNSNLRGIINPFPASKGIRAFPLQCIHIAEGHTKAV
LCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSAS
TSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHYIKMFDVTEGALG
TVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVG

--------------------------------------------------------------
>52530_52530_4_MED10-KIF21A_MED10_chr5_6377279_ENST00000255764_KIF21A_chr12_39752175_ENST00000541463_length(transcript)=4164nt_BP=317nt
CAGAGGAAACGGAAGTCGTATCTGTCCGGACGGAAGCAGGAAGCGGGAGCGTAGGGCCACGCCTGCGGCGCTGCTGGTTGAGGCTGTGTG
GGTCGGGGACGGGCCGAGGCGATGGCGGAGAAGTTTGACCACCTAGAGGAGCACCTGGAGAAGTTCGTGGAGAACATTCGGCAGCTCGGC
ATCATCGTCAGTGACTTCCAGCCCAGCAGCCAGGCCGGGCTCAACCAAAAGCTGAATTTTATTGTTACTGGCTTACAGGATATTGACAAG
TGCAGACAGCAGCTTCATGATATTACTGTACCGTTAGAAGTTTTTGACCAAACAATCATGATAGCATGTGTCAGCCCTTCAGACAGAGAC
TTTATGGAAACGTTAAACACCCTGAAATACGCCAATCGAGCTAGAAATATCAAGAATAAGGTGATGGTCAATCAGGACAGAGCTAGTCAG
CAAATCAATGCACTTCGTAGTGAAATCACACGACTTCAGATGGAGCTCATGGAGTACAAAACAGGTAAAAGAATAATTGACGAAGAGGGT
GTGGAAAGCATCAATGACATGTTTCATGAGAATGCTATGCTACAGACTGAAAATAATAACCTGCGTGTAAGAATTAAAGCCATGCAAGAG
ACGGTTGATGCATTGAGGTCCAGAATTACACAGCTTGTTAGTGATCAGGCCAACCATGTTCTTGCCAGAGCAGGTGAAGGAAATGAGGAG
ATTAGTAATATGATTCATAGTTATATAAAAGAAATCGAAGATCTCAGGGCAAAATTATTAGAAAGTGAAGCAGTGAATGAGAACCTTCGA
AAAAACTTGACAAGAGCCACAGCAAGAGCGCCATATTTCAGCGGATCATCAACTTTTTCTCCTACCATACTATCCTCAGACAAAGAAACC
ATTGAAATTATAGACCTAGCAAAAAAAGATTTAGAGAAGTTGAAAAGAAAAGAAAAGAGGAAGAAAAAAAGTGTGGCTGGTAAAGAGGAT
AATACAGACACTGACCAAGAGAAGAAAGAAGAAAAGGGTGTTTCGGAAAGAGAAAACAATGAATTAGAAGTGGAAGAAAGTCAAGAAGTG
AGTGATCATGAGGATGAAGAAGAGGAGGAGGAGGAGGAGGAAGATGACATTGATGGGGGTGAAAGTTCTGATGAATCAGATTCTGAATCA
GATGAAAAAGCCAATTATCAAGCAGACTTGGCAAACATTACTTGTGAAATTGCAATTAAGCAAAAGCTGATTGATGAACTAGAAAACAGC
CAGAAAAGACTGCAGACTCTGAAAAAGCAGTATGAAGAGAAGCTAATGATGCTGCAACATAAAATTCGGGATACTCAGCTTGAAAGAGAC
CAGGTGCTTCAAAACTTAGGCTCGGTAGAATCTTACTCAGAAGAAAAAGCAAAAAAAGTTAGGTCTGAATATGAAAAGAAACTCCAAGCC
ATGAACAAAGAACTGCAGAGACTTCAAGCAGCTCAAAAAGAACATGCAAGGTTGCTTAAAAATCAGTCTCAGTATGAAAAGCAATTGAAG
AAATTGCAGCAGGATGTGATGGAAATGAAAAAAACAAAGGTTCGCCTAATGAAACAAATGAAAGAAGAACAAGAGAAAGCCAGACTGACT
GAGTCTAGAAGAAACAGAGAGATTGCTCAGTTGAAAAAGGATCAACGTAAAAGAGATGTTACGGCTCTTCGTCGGCAAGTAAGACCCATG
TCAGATAAAGTGGCTGGGAAAGTTACTCGGAAGCTGAGTTCATCTGATGCACCTGCTCAGGACACAGGTTCCAGTGCAGCTGCTGTCGAA
ACAGATGCATCAAGGACAGGAGCCCAGCAGAAAATGAGAATTCCTGTGGCGAGAGTCCAGGCCTTACCAACGCCGGCAACAAATGGAAAC
AGGAAAAAATATCAGAGGAAAGGATTGACTGGCCGAGTGTTTATTTCCAAGACAGCTCGCATGAAGTGGCAGCTCCTTGAGCGCAGGGTC
ACAGACATCATCATGCAGAAGATGACCATTTCCAACATGGAGGCAGATATGAATAGACTCCTCAAGCAACGGGAGGAACTCACAAAAAGA
CGAGAGAAACTTTCAAAAAGAAGGGAGAAGATAGTCAAGGAGAATGGAGAGGGAGATAAAAATGTGGCTAATATCAATGAAGAGATGGAG
TCACTGACTGCTAATATCGATTACATCAATGACAGTATTTCTGATTGTCAGGCCAACATAATGCAGATGGAAGAAGCAAAGGAAGAAGGT
GAGACATTGGATGTTACTGCAGTCATTAATGCCTGCACCCTTACAGAAGCCCGATACCTGCTAGATCACTTCCTGTCAATGGGCATCAAT
AAGGGTCTTCAGGCTGCCCAGAAAGAGGCTCAAATTAAAGTACTGGAAGGTCGACTCAAACAAACAGAAATAACCAGTGCTACCCAAAAC
CAGCTCTTATTCCATATGTTGAAAGAGAAGGCAGAATTAAATCCTGAGCTAGATGCTTTACTAGGCCATGCTTTACAAGATCTAGATAGC
GTACCATTAGAAAATGTAGAGGATAGTACTGATGAGGATGCTCCTTTAAACAGCCCAGGATCAGAAGGAAGCACGCTGTCTTCAGATCTC
ATGAAGCTTTGTGGTGAAGTGAAACCTAAGAACAAGGCCCGAAGGAGAACCACCACTCAGATGGAATTGCTGTATGCAGATAGCAGTGAA
CTAGCTTCAGACACTAGTACAGGAGATGCCTCCTTGCCTGGCCCTCTCACACCTGTTGCAGAAGGGCAAGAGATTGGAATGAATACAGAG
ACAAGTGGTACTTCTGCTAGGGAAAAAGAGCTCTCTCCCCCACCTGGCTTACCTTCTAAGATAGGCAGCATTTCCAGGCAGTCATCTCTA
TCAGAAAAAAAAATTCCAGAGCCTTCTCCTGTAACAAGGAGAAAGGCATATGAGAAAGCAGAAAAATCAAAGGCCAAGGAACAAAAGCAC
TCAGATTCTGGAACTTCAGAGGCTAGTCTTTCACCTCCTTCTTCCCCACCAAGCCGGCCCCGTAATGAACTGAATGTTTTTAATCGTCTT
ACTGTTTCTCAGGGAAACACATCAGTTCAGCAGGATAAGGGCATAATCAACCCATTTCCTGCTTCAAAAGGAATCAGAGCTTTTCCACTT
CAGTGTATTCACATAGCTGAAGGGCATACAAAAGCTGTGCTCTGTGTGGATTCTACTGATGATCTCCTCTTCACTGGATCAAAAGATCGT
ACTTGTAAAGTATGGAATCTGGTGACTGGGCAGGAAATAATGTCACTGGGGGGTCATCCCAACAATGTCGTGTCTGTAAAATACTGTAAT
TATACCAGTTTGGTCTTCACTGTATCAACATCTTATATTAAGGTGTGGGATATCAGAGATTCAGCAAAGTGCATTCGAACACTAACGTCT
TCAGGTCAAGTTACTCTTGGAGATGCTTGTTCTGCAAGTACCAGTCGAACAGTAGCTATTCCTTCTGGAGAGAACCAGATCAATCAAATT
GCCCTAAACCCAACTGGCACCTTCCTCTATGCTGCTTCTGGAAATGCTGTCAGGATGTGGGATCTTAAAAGGTTTCAGTCTACAGGAAAG
TTAACAGGACACCTAGGCCCTGTTATGTGCCTTACTGTGGATCAGATTTCCAGTGGACAAGATCTAATCATCACTGGCTCCAAGGATCAT
TACATCAAAATGTTTGATGTTACAGAAGGAGCTCTTGGGACTGTGAGTCCCACCCACAATTTTGAACCCCCTCATTATGATGGCATAGAA
GCACTAACCATTCAAGGGGATAACCTATTTAGTGGGTCTAGAGATAATGGAATCAAGAAATGGGACTTAACTCAAAAAGACCTTCTTCAG
CAAGTTCCAAATGCACATAAGGATTGGGTCTGTGCCCTGGGAGTGGTGCCAGACCACCCAGTTTTGCTCAGTGGCTGCAGAGGGGGCATT
TTGAAAGTCTGGAACATGGATACTTTTATGCCAGTGGGAGAGATGAAGGGTCATGATAGTCCTATCAATGCCATATGTGTTAATTCCACC
CACATTTTTACTGCAGCTGATGATCGAACTGTGAGAATTTGGAAGGCTCGCAATTTGCAAGATGGTCAGATCTCTGACACAGGAGATCTG

>52530_52530_4_MED10-KIF21A_MED10_chr5_6377279_ENST00000255764_KIF21A_chr12_39752175_ENST00000541463_length(amino acids)=1350AA_BP=67
MAEKFDHLEEHLEKFVENIRQLGIIVSDFQPSSQAGLNQKLNFIVTGLQDIDKCRQQLHDITVPLEVFDQTIMIACVSPSDRDFMETLNT
LKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRS
RITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLA
KKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQ
ADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQR
LQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDVTALRRQVRPMSDKVAGK
VTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQK
MTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTA
VINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVE
DSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAR
EKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNT
SVQQDKGIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFT
VSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGP
VMCLTVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHK
DWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN

--------------------------------------------------------------
>52530_52530_5_MED10-KIF21A_MED10_chr5_6377279_ENST00000255764_KIF21A_chr12_39752175_ENST00000544797_length(transcript)=4249nt_BP=317nt
CAGAGGAAACGGAAGTCGTATCTGTCCGGACGGAAGCAGGAAGCGGGAGCGTAGGGCCACGCCTGCGGCGCTGCTGGTTGAGGCTGTGTG
GGTCGGGGACGGGCCGAGGCGATGGCGGAGAAGTTTGACCACCTAGAGGAGCACCTGGAGAAGTTCGTGGAGAACATTCGGCAGCTCGGC
ATCATCGTCAGTGACTTCCAGCCCAGCAGCCAGGCCGGGCTCAACCAAAAGCTGAATTTTATTGTTACTGGCTTACAGGATATTGACAAG
TGCAGACAGCAGCTTCATGATATTACTGTACCGTTAGAAGTTTTTGACCAAACAATCATGATAGCATGTGTCAGCCCTTCAGACAGAGAC
TTTATGGAAACGTTAAACACCCTGAAATACGCCAATCGAGCTAGAAATATCAAGAATAAGGTGATGGTCAATCAGGACAGAGCTAGTCAG
CAAATCAATGCACTTCGTAGTGAAATCACACGACTTCAGATGGAGCTCATGGAGTACAAAACAGGTAAAAGAATAATTGACGAAGAGGGT
GTGGAAAGCATCAATGACATGTTTCATGAGAATGCTATGCTACAGACTGAAAATAATAACCTGCGTGTAAGAATTAAAGCCATGCAAGAG
ACGGTTGATGCATTGAGGTCCAGAATTACACAGCTTGTTAGTGATCAGGCCAACCATGTTCTTGCCAGAGCAGGTGAAGGAAATGAGGAG
ATTAGTAATATGATTCATAGTTATATAAAAGAAATCGAAGATCTCAGGGCAAAATTATTAGAAAGTGAAGCAGTGAATGAGAACCTTCGA
AAAAACTTGACAAGAGCCACAGCAAGAGCGCCATATTTCAGCGGATCATCAACTTTTTCTCCTACCATACTATCCTCAGACAAAGAAACC
ATTGAAATTATAGACCTAGCAAAAAAAGATTTAGAGAAGTTGAAAAGAAAAGAAAAGAGGAAGAAAAAAAGTGTGGCTGGTAAAGAGGAT
AATACAGACACTGACCAAGAGAAGAAAGAAGAAAAGGGTGTTTCGGAAAGAGAAAACAATGAATTAGAAGTGGAAGAAAGTCAAGAAGTG
AGTGATCATGAGGATGAAGAAGAGGAGGAGGAGGAGGAGGAAGATGACATTGATGGGGGTGAAAGTTCTGATGAATCAGATTCTGAATCA
GATGAAAAAGCCAATTATCAAGCAGACTTGGCAAACATTACTTGTGAAATTGCAATTAAGCAAAAGCTGATTGATGAACTAGAAAACAGC
CAGAAAAGACTGCAGACTCTGAAAAAGCAGTATGAAGAGAAGCTAATGATGCTGCAACATAAAATTCGGGATACTCAGCTTGAAAGAGAC
CAGGTGCTTCAAAACTTAGGCTCGGTAGAATCTTACTCAGAAGAAAAAGCAAAAAAAGTTAGGTCTGAATATGAAAAGAAACTCCAAGCC
ATGAACAAAGAACTGCAGAGACTTCAAGCAGCTCAAAAAGAACATGCAAGGTTGCTTAAAAATCAGTCTCAGTATGAAAAGCAATTGAAG
AAATTGCAGCAGGATGTGATGGAAATGAAAAAAACAAAGGTTCGCCTAATGAAACAAATGAAAGAAGAACAAGAGAAAGCCAGACTGACT
GAGTCTAGAAGAAACAGAGAGATTGCTCAGTTGAAAAAGGATCAACGTAAAAGAGATCATCAACTTAGACTTCTGGAAGCCCAAAAAAGA
AACCAAGAAGTGGTTCTACGTCGCAAAACTGAAGAGGTTACGGCTCTTCGTCGGCAAGTAAGACCCATGTCAGATAAAGTGGCTGGGAAA
GTTACTCGGAAGCTGAGTTCATCTGATGCACCTGCTCAGGACACAGGTTCCAGTGCAGCTGCTGTCGAAACAGATGCATCAAGGACAGGA
GCCCAGCAGAAAATGAGAATTCCTGTGGCGAGAGTCCAGGCCTTACCAACGCCGGCAACAAATGGAAACAGGAAAAAATATCAGAGGAAA
GGATTGACTGGCCGAGTGTTTATTTCCAAGACAGCTCGCATGAAGTGGCAGCTCCTTGAGCGCAGGGTCACAGACATCATCATGCAGAAG
ATGACCATTTCCAACATGGAGGCAGATATGAATAGACTCCTCAAGCAACGGGAGGAACTCACAAAAAGACGAGAGAAACTTTCAAAAAGA
AGGGAGAAGATAGTCAAGGAGAATGGAGAGGGAGATAAAAATGTGGCTAATATCAATGAAGAGATGGAGTCACTGACTGCTAATATCGAT
TACATCAATGACAGTATTTCTGATTGTCAGGCCAACATAATGCAGATGGAAGAAGCAAAGGAAGAAGGTGAGACATTGGATGTTACTGCA
GTCATTAATGCCTGCACCCTTACAGAAGCCCGATACCTGCTAGATCACTTCCTGTCAATGGGCATCAATAAGGGTCTTCAGGCTGCCCAG
AAAGAGGCTCAAATTAAAGTACTGGAAGGTCGACTCAAACAAACAGAAATAACCAGTGCTACCCAAAACCAGCTCTTATTCCATATGTTG
AAAGAGAAGGCAGAATTAAATCCTGAGCTAGATGCTTTACTAGGCCATGCTTTACAAGAAAATGTAGAGGATAGTACTGATGAGGATGCT
CCTTTAAACAGCCCAGGATCAGAAGGAAGCACGCTGTCTTCAGATCTCATGAAGCTTTGTGGTGAAGTGAAACCTAAGAACAAGGCCCGA
AGGAGAACCACCACTCAGATGGAATTGCTGTATGCAGATAGCAGTGAACTAGCTTCAGACACTAGTACAGGAGATGCCTCCTTGCCTGGC
CCTCTCACACCTGTTGCAGAAGGGCAAGAGATTGGAATGAATACAGAGACAAGTGGTACTTCTGCTAGGGAAAAAGAGCTCTCTCCCCCA
CCTGGCTTACCTTCTAAGATAGGCAGCATTTCCAGGCAGTCATCTCTATCAGAAAAAAAAATTCCAGAGCCTTCTCCTGTAACAAGGAGA
AAGGCATATGAGAAAGCAGAAAAATCAAAGGCCAAGGAACAAAAGCACTCAGATTCTGGAACTTCAGAGGCTAGTCTTTCACCTCCTTCT
TCCCCACCAAGCCGGCCCCGTAATGAACTGAATGTTTTTAATCGTCTTACTGTTTCTCAGGGAAACACATCAGTTCAGCAGGATAAGGGC
ATAATCAACCCATTTCCTGCTTCAAAAGGAATCAGAGCTTTTCCACTTCAGTGTATTCACATAGCTGAAGGGCATACAAAAGCTGTGCTC
TGTGTGGATTCTACTGATGATCTCCTCTTCACTGGATCAAAAGATCGTACTTGTAAAGTATGGAATCTGGTGACTGGGCAGGAAATAATG
TCACTGGGGGGTCATCCCAACAATGTCGTGTCTGTAAAATACTGTAATTATACCAGTTTGGTCTTCACTGTATCAACATCTTATATTAAG
GTGTGGGATATCAGAGATTCAGCAAAGTGCATTCGAACACTAACGTCTTCAGGTCAAGTTACTCTTGGAGATGCTTGTTCTGCAAGTACC
AGTCGAACAGTAGCTATTCCTTCTGGAGAGAACCAGATCAATCAAATTGCCCTAAACCCAACTGGCACCTTCCTCTATGCTGCTTCTGGA
AATGCTGTCAGGATGTGGGATCTTAAAAGGTTTCAGTCTACAGGAAAGTTAACAGGACACCTAGGCCCTGTTATGTGCCTTACTGTGGAT
CAGATTTCCAGTGGACAAGATCTAATCATCACTGGCTCCAAGGATCATTACATCAAAATGTTTGATGTTACAGAAGGAGCTCTTGGGACT
GTGAGTCCCACCCACAATTTTGAACCCCCTCATTATGATGGCATAGAAGCACTAACCATTCAAGGGGATAACCTATTTAGTGGGTCTAGA
GATAATGGAATCAAGAAATGGGACTTAACTCAAAAAGACCTTCTTCAGCAAGTTCCAAATGCACATAAGGATTGGGTCTGTGCCCTGGGA
GTGGTGCCAGACCACCCAGTTTTGCTCAGTGGCTGCAGAGGGGGCATTTTGAAAGTCTGGAACATGGATACTTTTATGCCAGTGGGAGAG
ATGAAGGGTCATGATAGTCCTATCAATGCCATATGTGTTAATTCCACCCACATTTTTACTGCAGCTGATGATCGAACTGTGAGAATTTGG
AAGGCTCGCAATTTGCAAGATGGTCAGATCTCTGACACAGGAGATCTGGGGGAAGATATTGCCAGTAATTAAACATGAATGAAGATAGGT

>52530_52530_5_MED10-KIF21A_MED10_chr5_6377279_ENST00000255764_KIF21A_chr12_39752175_ENST00000544797_length(amino acids)=1366AA_BP=67
MAEKFDHLEEHLEKFVENIRQLGIIVSDFQPSSQAGLNQKLNFIVTGLQDIDKCRQQLHDITVPLEVFDQTIMIACVSPSDRDFMETLNT
LKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRS
RITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLA
KKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQ
ADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQR
LQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLR
RKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVF
ISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSIS
DCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELN
PELDALLGHALQENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAE
GQEIGMNTETSGTSAREKELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPPSSPPSRPR
NELNVFNRLTVSQGNTSVQQDKGIINPFPASKGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPN
NVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWD
LKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKW
DLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MED10-KIF21A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MED10-KIF21A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MED10-KIF21A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource