FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:MED1-STAG1 (FusionGDB2 ID:52675)

Fusion Gene Summary for MED1-STAG1

check button Fusion gene summary
Fusion gene informationFusion gene name: MED1-STAG1
Fusion gene ID: 52675
HgeneTgene
Gene symbol

MED1

STAG1

Gene ID

8930

56937

Gene namemethyl-CpG binding domain 4, DNA glycosylaseprostate transmembrane protein, androgen induced 1
SynonymsMED1STAG1|TMEPAI
Cytomap

3q21.3

20q13.31

Type of geneprotein-codingprotein-coding
Descriptionmethyl-CpG-binding domain protein 43,N(4)-ethenocytosine glycosylaseG/5-fluorouracil mismatch glycosylase with biphasic kineticsG/T mismatch glycosylaseG/U mismatch glycosylasemethyl-CpG binding domain protein 4methyl-CpG-binding endonuclease 1methprotein TMEPAIsolid tumor-associated 1 proteintransmembrane, prostate androgen induced RNA
Modification date2020031320200313
UniProtAcc

Q15648

.
Ensembl transtripts involved in fusion geneENST00000300651, ENST00000394287, 
ENST00000434713, ENST00000480733, 
ENST00000536929, ENST00000236698, 
ENST00000383202, 
Fusion gene scores* DoF score42 X 23 X 11=1062616 X 17 X 8=2176
# samples 4123
** MAII scorelog2(41/10626*10)=-4.69583089796762
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(23/2176*10)=-3.24197279030596
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MED1 [Title/Abstract] AND STAG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMED1(37587367)-STAG1(136221621), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSTAG1

GO:0010991

negative regulation of SMAD protein complex assembly

20129061

TgeneSTAG1

GO:0030512

negative regulation of transforming growth factor beta receptor signaling pathway

24627487

TgeneSTAG1

GO:0060394

negative regulation of pathway-restricted SMAD protein phosphorylation

24627487


check buttonFusion gene breakpoints across MED1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across STAG1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A06OMED1chr17

37587367

-STAG1chr3

136221621

-


Top

Fusion Gene ORF analysis for MED1-STAG1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000300651ENST00000434713MED1chr17

37587367

-STAG1chr3

136221621

-
5CDS-5UTRENST00000394287ENST00000434713MED1chr17

37587367

-STAG1chr3

136221621

-
5CDS-intronENST00000300651ENST00000480733MED1chr17

37587367

-STAG1chr3

136221621

-
5CDS-intronENST00000300651ENST00000536929MED1chr17

37587367

-STAG1chr3

136221621

-
5CDS-intronENST00000394287ENST00000480733MED1chr17

37587367

-STAG1chr3

136221621

-
5CDS-intronENST00000394287ENST00000536929MED1chr17

37587367

-STAG1chr3

136221621

-
In-frameENST00000300651ENST00000236698MED1chr17

37587367

-STAG1chr3

136221621

-
In-frameENST00000300651ENST00000383202MED1chr17

37587367

-STAG1chr3

136221621

-
In-frameENST00000394287ENST00000236698MED1chr17

37587367

-STAG1chr3

136221621

-
In-frameENST00000394287ENST00000383202MED1chr17

37587367

-STAG1chr3

136221621

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394287MED1chr1737587367-ENST00000383202STAG1chr3136221621-597585520639551249
ENST00000394287MED1chr1737587367-ENST00000236698STAG1chr3136221621-586385520638441212
ENST00000300651MED1chr1737587367-ENST00000383202STAG1chr3136221621-599387322439731249
ENST00000300651MED1chr1737587367-ENST00000236698STAG1chr3136221621-588187322438621212

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394287ENST00000383202MED1chr1737587367-STAG1chr3136221621-0.0001471960.9998528
ENST00000394287ENST00000236698MED1chr1737587367-STAG1chr3136221621-0.0001713670.9998286
ENST00000300651ENST00000383202MED1chr1737587367-STAG1chr3136221621-0.000148230.9998517
ENST00000300651ENST00000236698MED1chr1737587367-STAG1chr3136221621-0.0001723710.9998276

Top

Fusion Genomic Features for MED1-STAG1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for MED1-STAG1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:37587367/chr3:136221621)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MED1

Q15648

.
FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (PubMed:10406464, PubMed:11867769, PubMed:12037571, PubMed:12218053, PubMed:12556447, PubMed:14636573, PubMed:15340084, PubMed:15471764, PubMed:15989967, PubMed:16574658, PubMed:9653119). Acts as a coactivator for GATA1-mediated transcriptional activation during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781). {ECO:0000269|PubMed:10406464, ECO:0000269|PubMed:11867769, ECO:0000269|PubMed:12037571, ECO:0000269|PubMed:12218053, ECO:0000269|PubMed:12556447, ECO:0000269|PubMed:14636573, ECO:0000269|PubMed:15340084, ECO:0000269|PubMed:15471764, ECO:0000269|PubMed:15989967, ECO:0000269|PubMed:16574658, ECO:0000269|PubMed:24245781, ECO:0000269|PubMed:9653119}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSTAG1chr17:37587367chr3:136221621ENST000003832026341065_10702251259.0Compositional biasNote=Poly-Ser
TgeneSTAG1chr17:37587367chr3:136221621ENST00000383202634684_6872251259.0Compositional biasNote=Poly-Asp
TgeneSTAG1chr17:37587367chr3:136221621ENST00000383202634296_3812251259.0DomainSCD

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-9171078_14822161582.0Compositional biasNote=Ser-rich
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-9171496_15292161582.0Compositional biasNote=Lys-rich
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-9181078_1482216557.0Compositional biasNote=Ser-rich
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-9181496_1529216557.0Compositional biasNote=Lys-rich
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-917604_6082161582.0MotifNote=LXXLL motif 1
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-917645_6492161582.0MotifNote=LXXLL motif 2
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-917875_9022161582.0MotifIntegrase domain-binding motif (IBM)
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-918604_608216557.0MotifNote=LXXLL motif 1
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-918645_649216557.0MotifNote=LXXLL motif 2
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-918875_902216557.0MotifIntegrase domain-binding motif (IBM)


Top

Fusion Gene Sequence for MED1-STAG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>52675_52675_1_MED1-STAG1_MED1_chr17_37587367_ENST00000300651_STAG1_chr3_136221621_ENST00000236698_length(transcript)=5881nt_BP=873nt
ACGGTTTATCTCGCGAATTTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAG
ATTGATCCTTCCCGGGAAGAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAG
GGCTTATCCTTTTGTGGCGGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGA
TGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGGAGA
AGAGGGTTGTGATGAGTTCTGGAGGGCATCAACATTTGGTCAGCTGTTTGGAGACATTGCAGAAGGCTCTCAAAGTAACATCTTTACCAG
CAATGACTGATCGTTTGGAGTCCATAGCAAGACAGAATGGACTGGGCTCTCATCTCAGTGCCAGTGGCACTGAATGTTACATCACGTCAG
ATATGTTCTATGTGGAAGTGCAGTTAGATCCTGCAGGACAGCTTTGTGATGTAAAAGTGGCTCACCATGGGGAGAATCCTGTGAGCTGTC
CGGAGCTTGTACAGCAGCTAAGGGAAAAAAATTTTGATGAATTTTCTAAGCACCTTAAGGGCCTTGTTAATCTGTATAACCTTCCAGGGG
ACAACAAACTGAAGACTAAAATGTACTTGGCTCTCCAATCCTTAGAACAAGATCTTTCTAAAATGGCAATTATGTACTGGAAAGCAACTA
ATGCTGGTCCCTTGGATAAGATTCTTCATGGAAGTGTTGGCTATCTCACACCAAGGAGTGGGGCCATGAAGCTCATGACTGCTCTGGTGA
ATGTTGCCTTAAACCTCAGTATTCATCAGGATAATACCCAGAGACAATATGAAGCCGAGAGAAATAAAATGATTGGGAAGAGAGCCAATG
AAAGGTTGGAGTTACTACTTCAGAAACGCAAAGAGCTGCAAGAAAATCAGGATGAAATCGAAAATATGATGAACTCTATTTTTAAGGGTA
TATTTGTTCATAGATACCGTGATGCTATTGCTGAGATTAGAGCCATTTGTATTGAAGAAATTGGAGTATGGATGAAAATGTATAGTGATG
CCTTCCTAAATGACAGTTACCTAAAATATGTTGGCTGGACTCTTCATGACAGGCAAGGGGAAGTCAGGCTGAAGTGTTTGAAAGCTCTGC
AGAGTCTATATACCAATAGAGAATTATTCCCCAAATTGGAACTATTCACTAACCGATTCAAGGATCGCATTGTATCAATGACACTTGATA
AAGAATATGATGTTGCTGTGGAAGCTATTCGATTGGTTACTCTGATACTTCATGGAAGTGAAGAAGCTCTTTCCAATGAAGACTGTGAAA
ATGTTTACCACTTGGTGTACTCGGCACATCGCCCTGTTGCTGTGGCAGCTGGAGAGTTCCTTCACAAAAAGCTATTTAGCAGACATGACC
CACAAGCAGAAGAAGCATTAGCAAAGAGGAGGGGAAGAAACAGCCCGAATGGAAACCTCATTAGGATGCTGGTTCTTTTCTTTCTTGAAA
GTGAGTTACATGAACATGCAGCCTACTTGGTGGACAGTTTATGGGAGAGCTCTCAAGAACTGTTGAAAGACTGGGAATGTATGACAGAGT
TGCTATTAGAAGAACCTGTTCAAGGAGAGGAAGCAATGTCTGATCGTCAAGAGAGTGCTCTTATAGAGCTAATGGTTTGTACAATTCGTC
AAGCTGCTGAGGCACATCCTCCAGTGGGAAGGGGTACCGGCAAGAGAGTGCTAACTGCCAAAGAAAGGAAAACTCAAATTGATGATAGAA
ACAAATTGACTGAACATTTTATTATTACACTTCCTATGTTACTGTCAAAGTATTCTGCAGATGCAGAGAAGGTAGCAAACTTGCTACAAA
TCCCACAGTATTTTGATTTAGAAATCTACAGCACAGGTAGAATGGAAAAGCATCTGGATGCTTTATTAAAACAGATTAAGTTTGTTGTGG
AGAAACACGTAGAATCAGATGTTCTAGAAGCCTGCAGTAAAACCTATAGTATCTTATGCAGTGAAGAATATACCATCCAGAACAGAGTTG
ACATAGCTCGAAGCCAGCTGATTGATGAGTTTGTAGATCGATTCAATCATTCTGTGGAAGACCTATTGCAAGAGGGAGAAGAAGCTGATG
ATGATGACATTTACAATGTTCTTTCTACATTAAAGCGGTTAACTTCTTTTCACAATGCACATGATCTCACAAAATGGGATCTCTTTGGTA
ATTGCTACAGATTATTGAAGACTGGAATTGAACATGGAGCCATGCCAGAACAGATAGTCGTGCAAGCACTGCAGTGTTCCCATTATTCGA
TTCTTTGGCAGTTGGTGAAAATTACTGATGGCTCTCCTTCCAAAGAGGATTTGTTGGTATTGAGGAAAACGGTGAAATCCTTTTTGGCTG
TTTGCCAGCAGTGCCTGTCTAATGTTAATACTCCAGTGAAAGAACAGGCTTTCATGTTACTCTGTGATCTTCTGATGATTTTCAGCCACC
AATTAATGACAGGTGGCAGAGAGGGCCTTCAGCCTTTGGTGTTCAATCCAGATACTGGACTCCAATCTGAACTCCTCAGTTTTGTGATGG
ATCACGTTTTTATTGACCAAGACGAGGAGAACCAGAGCATGGAGGGTGATGAAGAAGATGAAGCTAATAAAATTGAGGCCTTACATAAAA
GAAGGAATCTACTTGCTGCTTTCAGCAAACTTATCATTTATGACATTGTTGACATGCATGCAGCTGCAGACATCTTCAAACACTACATGA
AGTATTACAATGACTATGGTGATATTATTAAGGAAACACTGAGTAAAACCAGGCAGATTGATAAAATTCAGTGTGCCAAGACTCTCATTC
TCAGTTTGCAACAGTTATTTAATGAACTTGTTCAAGAGCAAGGTCCCAACCTAGATAGGACATCTGCCCATGTCAGTGGCATTAAAGAAC
TGGCACGTCGCTTTGCCCTTACATTTGGATTGGACCAGATTAAGACACGAGAAGCAGTTGCCACACTTCACAAGGATGGCATAGAGTTTG
CATTTAAATACCAAAATCAGAAAGGACAAGAGTATCCACCTCCTAATCTGGCTTTTCTTGAAGTACTAAGTGAATTTTCTTCTAAACTTC
TTCGACAGGACAAAAAGACAGTTCATTCATACCTAGAGAAATTCCTTACCGAGCAGATGATGGAAAGGAGGGAGGATGTATGGCTTCCAC
TCATCTCCTATAGAAATTCATTAGTCACTGGGGGTGAAGATGATAGAATGTCTGTGAACAGTGGAAGTAGCAGCAGCAAAACCTCATCAG
TAAGGAATAAGAAAGGACGACCTCCACTTCATAAAAAACGAGTAGAAGATGAGAGTCTGGATAACACATGGCTAAACAGGACTGACACCA
TGATTCAGACTCCTGGCCCCCTGCCAGCACCACAACTCACATCCACTGTACTGCGGGAGAACAGTCGGCCCATGGGAGACCAGATTCAAG
AACCTGAGTCTGAACATGGTTCTGAACCAGACTTTTTACACAATCGGGGTCTAATGGAGGAAGATGCTGAGCCCATCTTTGAAGATGTGA
TGATGTCATCCCGAAGCCAGTTAGAAGATATGAATGAAGAATTTGAGGACACCATGGTTATTGATCTGCCTCCATCAAGAAATCGGCGAG
AGAGAGCTGAGCTAAGGCCAGACTTCTTTGACTCTGCAGCTATCATAGAAGATGATTCAGGATTTGGAATGCCTATGTTCTGAAGTCTGA
AGAAAATTTACAAATCTGGAACTCTATTATTTAGAGCTAGAGGCCTATATACTGTGATAGCTTGTATGGGGAAAAACACTTTTGATGTGA
TCTGATTTGTTTTTTAATCAAATGATTAAGGTCAATCCCTTTTTGCAGTGACAGAAGAGGAGCATGTAAATTACCCAAGGGAATGTTGGT
GAATGTCAACTCAGAAAGACTGACCTGAAAATCATTTGTGTCCTACTATTGGACTTATCCCAATACAGATGTGTGTGTTTTTCTGGAGGG
AGGAAGAAATTTTAAATTTTTAAAACAGCTGTCAAGATAAACACTGTTATACACCTGTTTTATGAAAACTCAACATTGAGTAAAAAAAAA
CATATTTTTAACTTTATTTTCCTGTTGTACAATTTAAAAACCGTTTTAACATTTTGCCTTTTTATGTTTTAAAAGCTAACCATTTTTATT
AAACCTATGAGTAAGCAGCTCATCCTAATTGCGAAGAGTGTTTTGGAGTTCACTGGATTTGGTTGACCTTTGTGGAACACAAATAATGAA
GGAGCAGAACATTGACAAGCTAAGATGAAATTCTGACATAGTACATCTCTGCCAAAAACCACACACCCTCTGTGGATATGGATATGAATT
CCCAGATTTTATATACTCTTGAATAAAAGGTTTATTTTTATTTATAAGTGGGCATAAAATAAGAAATGTCCATGCAGCCATTTTTCCAAC
AGATGCTGTACACCGTTCATTTTATATAGACTAGGGAGATTCAAATACAGTGCATTTTCTATTGGTATTTGTTCTGTGCATTTTTAGCAA
CTTCTACCAGCAAATAAAGTATTCTCAGTAAAACGAAAATGATTCTCAAGTTATCAGTTTGCTGTTTTTACCACTTATTTCATGCCCTGC
CAAATTCAAGTTACACAGACTTCCATTTTCTTAAGATAATCAATCATGAAGAAATCCTTTATCAATCATTCAAAAGTAATTTTAAGTGTA
ACATAACTGTGTTTACTTCCCATGCACTTAATACCCTTATGCGCTAATTTTGTGAATTAAGTTTACTGATTATAGAAGTATGTGCTGCAT
AGAAGTCTGTGCTTAGAGGGTGAAGTTCCTAAGCTTACCTTGAATTACAGCTACATTTCAGTGTTAAATGTGCATATTAAGAATAATTCT
TTTGGGGAAAGAAATTATGAATCTTCAGGACAGTCTACAATGGTTTAGAGTTACATTCTGCCTAGACTTTTATGACTTGCTGCTATTGTT
TTAAAAACCCCACTTAGTCTCTCTCTTCCTTTCTGATTTCTAAAGTAAGCCTCAGAATTTCCAAACCAATTCATCCACAGCTGTTTCTGG
GCTGGTTTTTAAAGTAGCTGCAACAGAATCATGAGGCTTTCCCTTTTTATCAAATACGAAAAACATTTTTTAAAATTCTGCACACCCAGT
GATCATCTTTTGTGCGGGAAAGCAAGATGATGATGGATGATTTTATTCATCCTTTTAGTAAAGACACAAAACATTTTTCTCAACATTTGT
ACAGTTCTGAAAAAAACCTGGTCACCAAAAATATCTTCTCTGCTAATTCAGCAATTCTTGGGCTCCAGTTAGGGGAGCTGGGGCCTCACT
TTCTCCCAGAATTGTGGGCTTCACTGGAAGTGAAGGTGCAGGAATGACTGGACTGTCCACCCCAGCCCTGCCTGCCTGTGGTTTTGGCCA
GGGAGCAAGCCATGAGGTGCCCTGGCACATGCACAAATTGATCCTTTGCGTGACAGTCTTGTATGGAAAACAGATGCTGACAGAATTGTA
GACTACCATGCCACACAAAAAGGCTAAATATCTACTCCAATGGGTTTCCAGTTCAGTTTGAAGTCAATCAAATTTTTGTATTTTCGGTGT
CTCCTTGATTGGTTTTGCTAGTAATTCTGTAAATTGTACATTTGCAATATGAGGTTTTTTTTCCTTTTGTACAATTTGAAACTGATGCTT

>52675_52675_1_MED1-STAG1_MED1_chr17_37587367_ENST00000300651_STAG1_chr3_136221621_ENST00000236698_length(amino acids)=1212AA_BP=216
MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVSCLETLQKALKVTSLPAMTDRLESIARQNGL
GSHLSASGTECYITSDMFYVEVQLDPAGQLCDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSL
EQDLSKMAIMYWKATNAGPLDKILHGSVGYLTPRSGAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQE
NQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPKLEL
FTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNS
PNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTGK
RVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKHVESDVLEACSKT
YSILCSEEYTIQNRVDIARSQLIDEFVDRFNHSVEDLLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIEHGAM
PEQIVVQALQCSHYSILWQLVKITDGSPSKEDLLVLRKTVKSFLAVCQQCLSNVNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVF
NPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDYGDIIKETLS
KTRQIDKIQCAKTLILSLQQLFNELVQEQGPNLDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPP
NLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSSSKTSSVRNKKGRPPLHKKRV
EDESLDNTWLNRTDTMIQTPGPLPAPQLTSTVLRENSRPMGDQIQEPESEHGSEPDFLHNRGLMEEDAEPIFEDVMMSSRSQLEDMNEEF

--------------------------------------------------------------
>52675_52675_2_MED1-STAG1_MED1_chr17_37587367_ENST00000300651_STAG1_chr3_136221621_ENST00000383202_length(transcript)=5993nt_BP=873nt
ACGGTTTATCTCGCGAATTTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAG
ATTGATCCTTCCCGGGAAGAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAG
GGCTTATCCTTTTGTGGCGGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGA
TGAGTTCTCTCCTGGAACGGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGGAGA
AGAGGGTTGTGATGAGTTCTGGAGGGCATCAACATTTGGTCAGCTGTTTGGAGACATTGCAGAAGGCTCTCAAAGTAACATCTTTACCAG
CAATGACTGATCGTTTGGAGTCCATAGCAAGACAGAATGGACTGGGCTCTCATCTCAGTGCCAGTGGCACTGAATGTTACATCACGTCAG
ATATGTTCTATGTGGAAGTGCAGTTAGATCCTGCAGGACAGCTTTGTGATGTAAAAGTGGCTCACCATGGGGAGAATCCTGTGAGCTGTC
CGGAGCTTGTACAGCAGCTAAGGGAAAAAAATTTTGATGAATTTTCTAAGCACCTTAAGGGCCTTGTTAATCTGTATAACCTTCCAGGGG
ACAACAAACTGAAGACTAAAATGTACTTGGCTCTCCAATCCTTAGAACAAGATCTTTCTAAAATGGCAATTATGTACTGGAAAGCAACTA
ATGCTGGTCCCTTGGATAAGATTCTTCATGGAAGTGTTGGCTATCTCACACCAAGGAGTGGGGCCATGAAGCTCATGACTGCTCTGGTGA
ATGTTGCCTTAAACCTCAGTATTCATCAGGATAATACCCAGAGACAATATGAAGCCGAGAGAAATAAAATGATTGGGAAGAGAGCCAATG
AAAGGTTGGAGTTACTACTTCAGAAACGCAAAGAGCTGCAAGAAAATCAGGATGAAATCGAAAATATGATGAACTCTATTTTTAAGGGTA
TATTTGTTCATAGATACCGTGATGCTATTGCTGAGATTAGAGCCATTTGTATTGAAGAAATTGGAGTATGGATGAAAATGTATAGTGATG
CCTTCCTAAATGACAGTTACCTAAAATATGTTGGCTGGACTCTTCATGACAGGCAAGGGGAAGTCAGGCTGAAGTGTTTGAAAGCTCTGC
AGAGTCTATATACCAATAGAGAATTATTCCCCAAATTGGAACTATTCACTAACCGATTCAAGGATCGCATTGTATCAATGACACTTGATA
AAGAATATGATGTTGCTGTGGAAGCTATTCGATTGGTTACTCTGATACTTCATGGAAGTGAAGAAGCTCTTTCCAATGAAGACTGTGAAA
ATGTTTACCACTTGGTGTACTCGGCACATCGCCCTGTTGCTGTGGCAGCTGGAGAGTTCCTTCACAAAAAGCTATTTAGCAGACATGACC
CACAAGCAGAAGAAGCATTAGCAAAGAGGAGGGGAAGAAACAGCCCGAATGGAAACCTCATTAGGATGCTGGTTCTTTTCTTTCTTGAAA
GTGAGTTACATGAACATGCAGCCTACTTGGTGGACAGTTTATGGGAGAGCTCTCAAGAACTGTTGAAAGACTGGGAATGTATGACAGAGT
TGCTATTAGAAGAACCTGTTCAAGGAGAGGAAGCAATGTCTGATCGTCAAGAGAGTGCTCTTATAGAGCTAATGGTTTGTACAATTCGTC
AAGCTGCTGAGGCACATCCTCCAGTGGGAAGGGGTACCGGCAAGAGAGTGCTAACTGCCAAAGAAAGGAAAACTCAAATTGATGATAGAA
ACAAATTGACTGAACATTTTATTATTACACTTCCTATGTTACTGTCAAAGTATTCTGCAGATGCAGAGAAGGTAGCAAACTTGCTACAAA
TCCCACAGTATTTTGATTTAGAAATCTACAGCACAGGTAGAATGGAAAAGCATCTGGATGCTTTATTAAAACAGATTAAGTTTGTTGTGG
AGAAACACGTAGAATCAGATGTTCTAGAAGCCTGCAGTAAAACCTATAGTATCTTATGCAGTGAAGAATATACCATCCAGAACAGAGTTG
ACATAGCTCGAAGCCAGCTGATTGATGAGTTTGTAGATCGATTCAATCATTCTGTGGAAGACCTATTGCAAGAGGGAGAAGAAGCTGATG
ATGATGACATTTACAATGTTCTTTCTACATTAAAGCGGTTAACTTCTTTTCACAATGCACATGATCTCACAAAATGGGATCTCTTTGGTA
ATTGCTACAGATTATTGAAGACTGGAATTGAACATGGAGCCATGCCAGAACAGATAGTCGTGCAAGCACTGCAGTGTTCCCATTATTCGA
TTCTTTGGCAGTTGGTGAAAATTACTGATGGCTCTCCTTCCAAAGAGGATTTGTTGGTATTGAGGAAAACGGTGAAATCCTTTTTGGCTG
TTTGCCAGCAGTGCCTGTCTAATGTTAATACTCCAGTGAAAGAACAGGCTTTCATGTTACTCTGTGATCTTCTGATGATTTTCAGCCACC
AATTAATGACAGGTGGCAGAGAGGGCCTTCAGCCTTTGGTGTTCAATCCAGATACTGGACTCCAATCTGAACTCCTCAGTTTTGTGATGG
ATCACGTTTTTATTGACCAAGACGAGGAGAACCAGAGCATGGAGGGTGATGAAGAAGATGAAGCTAATAAAATTGAGGCCTTACATAAAA
GAAGGAATCTACTTGCTGCTTTCAGCAAACTTATCATTTATGACATTGTTGACATGCATGCAGCTGCAGACATCTTCAAACACTACATGA
AGTATTACAATGACTATGGTGATATTATTAAGGAAACACTGAGTAAAACCAGGCAGATTGATAAAATTCAGTGTGCCAAGACTCTCATTC
TCAGTTTGCAACAGTTATTTAATGAACTTGTTCAAGAGCAAGGTCCCAACCTAGATAGGACATCTGCCCATGTCAGTGGCATTAAAGAAC
TGGCACGTCGCTTTGCCCTTACATTTGGATTGGACCAGATTAAGACACGAGAAGCAGTTGCCACACTTCACAAGGATGGCATAGAGTTTG
CATTTAAATACCAAAATCAGAAAGGACAAGAGTATCCACCTCCTAATCTGGCTTTTCTTGAAGTACTAAGTGAATTTTCTTCTAAACTTC
TTCGACAGGACAAAAAGACAGTTCATTCATACCTAGAGAAATTCCTTACCGAGCAGATGATGGAAAGGAGGGAGGATGTATGGCTTCCAC
TCATCTCCTATAGAAATTCATTAGTCACTGGGGGTGAAGATGATAGAATGTCTGTGAACAGTGGAAGTAGCAGCAGCAAAACCTCATCAG
TAAGGAATAAGAAAGGACGACCTCCACTTCATAAAAAACGAGTAGAAGATGAGAGTCTGGATAACACATGGCTAAACAGGACTGACACCA
TGATTCAGACTCCTGGCCCCCTGCCAGCACCACAACTCACATCCACTGTACTGCGGGAGAACAGTCGGCCCATGGGAGACCAGATTCAAG
AACCTGAGTCTGAACATGGTTCTGAACCAGACTTTTTACACAATCCTCAGATGCAGATCTCTTGGTTAGGCCAGCCGAAGTTAGAAGACT
TAAATCGGAAGGACAGAACAGGAATGAACTACATGAAAGTGAGAACTGGAGTGAGGCATGCTGTTCGGGGTCTAATGGAGGAAGATGCTG
AGCCCATCTTTGAAGATGTGATGATGTCATCCCGAAGCCAGTTAGAAGATATGAATGAAGAATTTGAGGACACCATGGTTATTGATCTGC
CTCCATCAAGAAATCGGCGAGAGAGAGCTGAGCTAAGGCCAGACTTCTTTGACTCTGCAGCTATCATAGAAGATGATTCAGGATTTGGAA
TGCCTATGTTCTGAAGTCTGAAGAAAATTTACAAATCTGGAACTCTATTATTTAGAGCTAGAGGCCTATATACTGTGATAGCTTGTATGG
GGAAAAACACTTTTGATGTGATCTGATTTGTTTTTTAATCAAATGATTAAGGTCAATCCCTTTTTGCAGTGACAGAAGAGGAGCATGTAA
ATTACCCAAGGGAATGTTGGTGAATGTCAACTCAGAAAGACTGACCTGAAAATCATTTGTGTCCTACTATTGGACTTATCCCAATACAGA
TGTGTGTGTTTTTCTGGAGGGAGGAAGAAATTTTAAATTTTTAAAACAGCTGTCAAGATAAACACTGTTATACACCTGTTTTATGAAAAC
TCAACATTGAGTAAAAAAAAACATATTTTTAACTTTATTTTCCTGTTGTACAATTTAAAAACCGTTTTAACATTTTGCCTTTTTATGTTT
TAAAAGCTAACCATTTTTATTAAACCTATGAGTAAGCAGCTCATCCTAATTGCGAAGAGTGTTTTGGAGTTCACTGGATTTGGTTGACCT
TTGTGGAACACAAATAATGAAGGAGCAGAACATTGACAAGCTAAGATGAAATTCTGACATAGTACATCTCTGCCAAAAACCACACACCCT
CTGTGGATATGGATATGAATTCCCAGATTTTATATACTCTTGAATAAAAGGTTTATTTTTATTTATAAGTGGGCATAAAATAAGAAATGT
CCATGCAGCCATTTTTCCAACAGATGCTGTACACCGTTCATTTTATATAGACTAGGGAGATTCAAATACAGTGCATTTTCTATTGGTATT
TGTTCTGTGCATTTTTAGCAACTTCTACCAGCAAATAAAGTATTCTCAGTAAAACGAAAATGATTCTCAAGTTATCAGTTTGCTGTTTTT
ACCACTTATTTCATGCCCTGCCAAATTCAAGTTACACAGACTTCCATTTTCTTAAGATAATCAATCATGAAGAAATCCTTTATCAATCAT
TCAAAAGTAATTTTAAGTGTAACATAACTGTGTTTACTTCCCATGCACTTAATACCCTTATGCGCTAATTTTGTGAATTAAGTTTACTGA
TTATAGAAGTATGTGCTGCATAGAAGTCTGTGCTTAGAGGGTGAAGTTCCTAAGCTTACCTTGAATTACAGCTACATTTCAGTGTTAAAT
GTGCATATTAAGAATAATTCTTTTGGGGAAAGAAATTATGAATCTTCAGGACAGTCTACAATGGTTTAGAGTTACATTCTGCCTAGACTT
TTATGACTTGCTGCTATTGTTTTAAAAACCCCACTTAGTCTCTCTCTTCCTTTCTGATTTCTAAAGTAAGCCTCAGAATTTCCAAACCAA
TTCATCCACAGCTGTTTCTGGGCTGGTTTTTAAAGTAGCTGCAACAGAATCATGAGGCTTTCCCTTTTTATCAAATACGAAAAACATTTT
TTAAAATTCTGCACACCCAGTGATCATCTTTTGTGCGGGAAAGCAAGATGATGATGGATGATTTTATTCATCCTTTTAGTAAAGACACAA
AACATTTTTCTCAACATTTGTACAGTTCTGAAAAAAACCTGGTCACCAAAAATATCTTCTCTGCTAATTCAGCAATTCTTGGGCTCCAGT
TAGGGGAGCTGGGGCCTCACTTTCTCCCAGAATTGTGGGCTTCACTGGAAGTGAAGGTGCAGGAATGACTGGACTGTCCACCCCAGCCCT
GCCTGCCTGTGGTTTTGGCCAGGGAGCAAGCCATGAGGTGCCCTGGCACATGCACAAATTGATCCTTTGCGTGACAGTCTTGTATGGAAA
ACAGATGCTGACAGAATTGTAGACTACCATGCCACACAAAAAGGCTAAATATCTACTCCAATGGGTTTCCAGTTCAGTTTGAAGTCAATC
AAATTTTTGTATTTTCGGTGTCTCCTTGATTGGTTTTGCTAGTAATTCTGTAAATTGTACATTTGCAATATGAGGTTTTTTTTCCTTTTG

>52675_52675_2_MED1-STAG1_MED1_chr17_37587367_ENST00000300651_STAG1_chr3_136221621_ENST00000383202_length(amino acids)=1249AA_BP=216
MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVSCLETLQKALKVTSLPAMTDRLESIARQNGL
GSHLSASGTECYITSDMFYVEVQLDPAGQLCDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSL
EQDLSKMAIMYWKATNAGPLDKILHGSVGYLTPRSGAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQE
NQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPKLEL
FTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNS
PNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTGK
RVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKHVESDVLEACSKT
YSILCSEEYTIQNRVDIARSQLIDEFVDRFNHSVEDLLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIEHGAM
PEQIVVQALQCSHYSILWQLVKITDGSPSKEDLLVLRKTVKSFLAVCQQCLSNVNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVF
NPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDYGDIIKETLS
KTRQIDKIQCAKTLILSLQQLFNELVQEQGPNLDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPP
NLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSSSKTSSVRNKKGRPPLHKKRV
EDESLDNTWLNRTDTMIQTPGPLPAPQLTSTVLRENSRPMGDQIQEPESEHGSEPDFLHNPQMQISWLGQPKLEDLNRKDRTGMNYMKVR

--------------------------------------------------------------
>52675_52675_3_MED1-STAG1_MED1_chr17_37587367_ENST00000394287_STAG1_chr3_136221621_ENST00000236698_length(transcript)=5863nt_BP=855nt
TTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAGATTGATCCTTCCCGGGAA
GAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAGGGCTTATCCTTTTGTGGC
GGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAAC
GGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGGAGAAGAGGGTTGTGATGAGTT
CTGGAGGGCATCAACATTTGGTCAGCTGTTTGGAGACATTGCAGAAGGCTCTCAAAGTAACATCTTTACCAGCAATGACTGATCGTTTGG
AGTCCATAGCAAGACAGAATGGACTGGGCTCTCATCTCAGTGCCAGTGGCACTGAATGTTACATCACGTCAGATATGTTCTATGTGGAAG
TGCAGTTAGATCCTGCAGGACAGCTTTGTGATGTAAAAGTGGCTCACCATGGGGAGAATCCTGTGAGCTGTCCGGAGCTTGTACAGCAGC
TAAGGGAAAAAAATTTTGATGAATTTTCTAAGCACCTTAAGGGCCTTGTTAATCTGTATAACCTTCCAGGGGACAACAAACTGAAGACTA
AAATGTACTTGGCTCTCCAATCCTTAGAACAAGATCTTTCTAAAATGGCAATTATGTACTGGAAAGCAACTAATGCTGGTCCCTTGGATA
AGATTCTTCATGGAAGTGTTGGCTATCTCACACCAAGGAGTGGGGCCATGAAGCTCATGACTGCTCTGGTGAATGTTGCCTTAAACCTCA
GTATTCATCAGGATAATACCCAGAGACAATATGAAGCCGAGAGAAATAAAATGATTGGGAAGAGAGCCAATGAAAGGTTGGAGTTACTAC
TTCAGAAACGCAAAGAGCTGCAAGAAAATCAGGATGAAATCGAAAATATGATGAACTCTATTTTTAAGGGTATATTTGTTCATAGATACC
GTGATGCTATTGCTGAGATTAGAGCCATTTGTATTGAAGAAATTGGAGTATGGATGAAAATGTATAGTGATGCCTTCCTAAATGACAGTT
ACCTAAAATATGTTGGCTGGACTCTTCATGACAGGCAAGGGGAAGTCAGGCTGAAGTGTTTGAAAGCTCTGCAGAGTCTATATACCAATA
GAGAATTATTCCCCAAATTGGAACTATTCACTAACCGATTCAAGGATCGCATTGTATCAATGACACTTGATAAAGAATATGATGTTGCTG
TGGAAGCTATTCGATTGGTTACTCTGATACTTCATGGAAGTGAAGAAGCTCTTTCCAATGAAGACTGTGAAAATGTTTACCACTTGGTGT
ACTCGGCACATCGCCCTGTTGCTGTGGCAGCTGGAGAGTTCCTTCACAAAAAGCTATTTAGCAGACATGACCCACAAGCAGAAGAAGCAT
TAGCAAAGAGGAGGGGAAGAAACAGCCCGAATGGAAACCTCATTAGGATGCTGGTTCTTTTCTTTCTTGAAAGTGAGTTACATGAACATG
CAGCCTACTTGGTGGACAGTTTATGGGAGAGCTCTCAAGAACTGTTGAAAGACTGGGAATGTATGACAGAGTTGCTATTAGAAGAACCTG
TTCAAGGAGAGGAAGCAATGTCTGATCGTCAAGAGAGTGCTCTTATAGAGCTAATGGTTTGTACAATTCGTCAAGCTGCTGAGGCACATC
CTCCAGTGGGAAGGGGTACCGGCAAGAGAGTGCTAACTGCCAAAGAAAGGAAAACTCAAATTGATGATAGAAACAAATTGACTGAACATT
TTATTATTACACTTCCTATGTTACTGTCAAAGTATTCTGCAGATGCAGAGAAGGTAGCAAACTTGCTACAAATCCCACAGTATTTTGATT
TAGAAATCTACAGCACAGGTAGAATGGAAAAGCATCTGGATGCTTTATTAAAACAGATTAAGTTTGTTGTGGAGAAACACGTAGAATCAG
ATGTTCTAGAAGCCTGCAGTAAAACCTATAGTATCTTATGCAGTGAAGAATATACCATCCAGAACAGAGTTGACATAGCTCGAAGCCAGC
TGATTGATGAGTTTGTAGATCGATTCAATCATTCTGTGGAAGACCTATTGCAAGAGGGAGAAGAAGCTGATGATGATGACATTTACAATG
TTCTTTCTACATTAAAGCGGTTAACTTCTTTTCACAATGCACATGATCTCACAAAATGGGATCTCTTTGGTAATTGCTACAGATTATTGA
AGACTGGAATTGAACATGGAGCCATGCCAGAACAGATAGTCGTGCAAGCACTGCAGTGTTCCCATTATTCGATTCTTTGGCAGTTGGTGA
AAATTACTGATGGCTCTCCTTCCAAAGAGGATTTGTTGGTATTGAGGAAAACGGTGAAATCCTTTTTGGCTGTTTGCCAGCAGTGCCTGT
CTAATGTTAATACTCCAGTGAAAGAACAGGCTTTCATGTTACTCTGTGATCTTCTGATGATTTTCAGCCACCAATTAATGACAGGTGGCA
GAGAGGGCCTTCAGCCTTTGGTGTTCAATCCAGATACTGGACTCCAATCTGAACTCCTCAGTTTTGTGATGGATCACGTTTTTATTGACC
AAGACGAGGAGAACCAGAGCATGGAGGGTGATGAAGAAGATGAAGCTAATAAAATTGAGGCCTTACATAAAAGAAGGAATCTACTTGCTG
CTTTCAGCAAACTTATCATTTATGACATTGTTGACATGCATGCAGCTGCAGACATCTTCAAACACTACATGAAGTATTACAATGACTATG
GTGATATTATTAAGGAAACACTGAGTAAAACCAGGCAGATTGATAAAATTCAGTGTGCCAAGACTCTCATTCTCAGTTTGCAACAGTTAT
TTAATGAACTTGTTCAAGAGCAAGGTCCCAACCTAGATAGGACATCTGCCCATGTCAGTGGCATTAAAGAACTGGCACGTCGCTTTGCCC
TTACATTTGGATTGGACCAGATTAAGACACGAGAAGCAGTTGCCACACTTCACAAGGATGGCATAGAGTTTGCATTTAAATACCAAAATC
AGAAAGGACAAGAGTATCCACCTCCTAATCTGGCTTTTCTTGAAGTACTAAGTGAATTTTCTTCTAAACTTCTTCGACAGGACAAAAAGA
CAGTTCATTCATACCTAGAGAAATTCCTTACCGAGCAGATGATGGAAAGGAGGGAGGATGTATGGCTTCCACTCATCTCCTATAGAAATT
CATTAGTCACTGGGGGTGAAGATGATAGAATGTCTGTGAACAGTGGAAGTAGCAGCAGCAAAACCTCATCAGTAAGGAATAAGAAAGGAC
GACCTCCACTTCATAAAAAACGAGTAGAAGATGAGAGTCTGGATAACACATGGCTAAACAGGACTGACACCATGATTCAGACTCCTGGCC
CCCTGCCAGCACCACAACTCACATCCACTGTACTGCGGGAGAACAGTCGGCCCATGGGAGACCAGATTCAAGAACCTGAGTCTGAACATG
GTTCTGAACCAGACTTTTTACACAATCGGGGTCTAATGGAGGAAGATGCTGAGCCCATCTTTGAAGATGTGATGATGTCATCCCGAAGCC
AGTTAGAAGATATGAATGAAGAATTTGAGGACACCATGGTTATTGATCTGCCTCCATCAAGAAATCGGCGAGAGAGAGCTGAGCTAAGGC
CAGACTTCTTTGACTCTGCAGCTATCATAGAAGATGATTCAGGATTTGGAATGCCTATGTTCTGAAGTCTGAAGAAAATTTACAAATCTG
GAACTCTATTATTTAGAGCTAGAGGCCTATATACTGTGATAGCTTGTATGGGGAAAAACACTTTTGATGTGATCTGATTTGTTTTTTAAT
CAAATGATTAAGGTCAATCCCTTTTTGCAGTGACAGAAGAGGAGCATGTAAATTACCCAAGGGAATGTTGGTGAATGTCAACTCAGAAAG
ACTGACCTGAAAATCATTTGTGTCCTACTATTGGACTTATCCCAATACAGATGTGTGTGTTTTTCTGGAGGGAGGAAGAAATTTTAAATT
TTTAAAACAGCTGTCAAGATAAACACTGTTATACACCTGTTTTATGAAAACTCAACATTGAGTAAAAAAAAACATATTTTTAACTTTATT
TTCCTGTTGTACAATTTAAAAACCGTTTTAACATTTTGCCTTTTTATGTTTTAAAAGCTAACCATTTTTATTAAACCTATGAGTAAGCAG
CTCATCCTAATTGCGAAGAGTGTTTTGGAGTTCACTGGATTTGGTTGACCTTTGTGGAACACAAATAATGAAGGAGCAGAACATTGACAA
GCTAAGATGAAATTCTGACATAGTACATCTCTGCCAAAAACCACACACCCTCTGTGGATATGGATATGAATTCCCAGATTTTATATACTC
TTGAATAAAAGGTTTATTTTTATTTATAAGTGGGCATAAAATAAGAAATGTCCATGCAGCCATTTTTCCAACAGATGCTGTACACCGTTC
ATTTTATATAGACTAGGGAGATTCAAATACAGTGCATTTTCTATTGGTATTTGTTCTGTGCATTTTTAGCAACTTCTACCAGCAAATAAA
GTATTCTCAGTAAAACGAAAATGATTCTCAAGTTATCAGTTTGCTGTTTTTACCACTTATTTCATGCCCTGCCAAATTCAAGTTACACAG
ACTTCCATTTTCTTAAGATAATCAATCATGAAGAAATCCTTTATCAATCATTCAAAAGTAATTTTAAGTGTAACATAACTGTGTTTACTT
CCCATGCACTTAATACCCTTATGCGCTAATTTTGTGAATTAAGTTTACTGATTATAGAAGTATGTGCTGCATAGAAGTCTGTGCTTAGAG
GGTGAAGTTCCTAAGCTTACCTTGAATTACAGCTACATTTCAGTGTTAAATGTGCATATTAAGAATAATTCTTTTGGGGAAAGAAATTAT
GAATCTTCAGGACAGTCTACAATGGTTTAGAGTTACATTCTGCCTAGACTTTTATGACTTGCTGCTATTGTTTTAAAAACCCCACTTAGT
CTCTCTCTTCCTTTCTGATTTCTAAAGTAAGCCTCAGAATTTCCAAACCAATTCATCCACAGCTGTTTCTGGGCTGGTTTTTAAAGTAGC
TGCAACAGAATCATGAGGCTTTCCCTTTTTATCAAATACGAAAAACATTTTTTAAAATTCTGCACACCCAGTGATCATCTTTTGTGCGGG
AAAGCAAGATGATGATGGATGATTTTATTCATCCTTTTAGTAAAGACACAAAACATTTTTCTCAACATTTGTACAGTTCTGAAAAAAACC
TGGTCACCAAAAATATCTTCTCTGCTAATTCAGCAATTCTTGGGCTCCAGTTAGGGGAGCTGGGGCCTCACTTTCTCCCAGAATTGTGGG
CTTCACTGGAAGTGAAGGTGCAGGAATGACTGGACTGTCCACCCCAGCCCTGCCTGCCTGTGGTTTTGGCCAGGGAGCAAGCCATGAGGT
GCCCTGGCACATGCACAAATTGATCCTTTGCGTGACAGTCTTGTATGGAAAACAGATGCTGACAGAATTGTAGACTACCATGCCACACAA
AAAGGCTAAATATCTACTCCAATGGGTTTCCAGTTCAGTTTGAAGTCAATCAAATTTTTGTATTTTCGGTGTCTCCTTGATTGGTTTTGC
TAGTAATTCTGTAAATTGTACATTTGCAATATGAGGTTTTTTTTCCTTTTGTACAATTTGAAACTGATGCTTCACCTTTCCTTTAATAAA

>52675_52675_3_MED1-STAG1_MED1_chr17_37587367_ENST00000394287_STAG1_chr3_136221621_ENST00000236698_length(amino acids)=1212AA_BP=216
MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVSCLETLQKALKVTSLPAMTDRLESIARQNGL
GSHLSASGTECYITSDMFYVEVQLDPAGQLCDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSL
EQDLSKMAIMYWKATNAGPLDKILHGSVGYLTPRSGAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQE
NQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPKLEL
FTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNS
PNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTGK
RVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKHVESDVLEACSKT
YSILCSEEYTIQNRVDIARSQLIDEFVDRFNHSVEDLLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIEHGAM
PEQIVVQALQCSHYSILWQLVKITDGSPSKEDLLVLRKTVKSFLAVCQQCLSNVNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVF
NPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDYGDIIKETLS
KTRQIDKIQCAKTLILSLQQLFNELVQEQGPNLDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPP
NLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSSSKTSSVRNKKGRPPLHKKRV
EDESLDNTWLNRTDTMIQTPGPLPAPQLTSTVLRENSRPMGDQIQEPESEHGSEPDFLHNRGLMEEDAEPIFEDVMMSSRSQLEDMNEEF

--------------------------------------------------------------
>52675_52675_4_MED1-STAG1_MED1_chr17_37587367_ENST00000394287_STAG1_chr3_136221621_ENST00000383202_length(transcript)=5975nt_BP=855nt
TTTGGGAAGTTCCGTTGGGGAAGATGGCGGCGGCCTCGAGCACCCTTCTCTTCTTGCCGCCGGGGACTTCAGATTGATCCTTCCCGGGAA
GAGTAGGGACTGCTGGTGCCCTGCGTCCCGGGATCCCGAGCCAACTTGTTTCCTCCGTTAGTGGTGGGGAAGGGCTTATCCTTTTGTGGC
GGATCTAGCTTCTCCTCGCCTTCAGGATGAAAGCTCAGGGGGAAACCGAGGAGTCAGAAAAGCTGAGTAAGATGAGTTCTCTCCTGGAAC
GGCTCCATGCAAAATTTAACCAAAATAGACCCTGGAGTGAAACCATTAAGCTTGTGCGTCAAGTCATGGAGAAGAGGGTTGTGATGAGTT
CTGGAGGGCATCAACATTTGGTCAGCTGTTTGGAGACATTGCAGAAGGCTCTCAAAGTAACATCTTTACCAGCAATGACTGATCGTTTGG
AGTCCATAGCAAGACAGAATGGACTGGGCTCTCATCTCAGTGCCAGTGGCACTGAATGTTACATCACGTCAGATATGTTCTATGTGGAAG
TGCAGTTAGATCCTGCAGGACAGCTTTGTGATGTAAAAGTGGCTCACCATGGGGAGAATCCTGTGAGCTGTCCGGAGCTTGTACAGCAGC
TAAGGGAAAAAAATTTTGATGAATTTTCTAAGCACCTTAAGGGCCTTGTTAATCTGTATAACCTTCCAGGGGACAACAAACTGAAGACTA
AAATGTACTTGGCTCTCCAATCCTTAGAACAAGATCTTTCTAAAATGGCAATTATGTACTGGAAAGCAACTAATGCTGGTCCCTTGGATA
AGATTCTTCATGGAAGTGTTGGCTATCTCACACCAAGGAGTGGGGCCATGAAGCTCATGACTGCTCTGGTGAATGTTGCCTTAAACCTCA
GTATTCATCAGGATAATACCCAGAGACAATATGAAGCCGAGAGAAATAAAATGATTGGGAAGAGAGCCAATGAAAGGTTGGAGTTACTAC
TTCAGAAACGCAAAGAGCTGCAAGAAAATCAGGATGAAATCGAAAATATGATGAACTCTATTTTTAAGGGTATATTTGTTCATAGATACC
GTGATGCTATTGCTGAGATTAGAGCCATTTGTATTGAAGAAATTGGAGTATGGATGAAAATGTATAGTGATGCCTTCCTAAATGACAGTT
ACCTAAAATATGTTGGCTGGACTCTTCATGACAGGCAAGGGGAAGTCAGGCTGAAGTGTTTGAAAGCTCTGCAGAGTCTATATACCAATA
GAGAATTATTCCCCAAATTGGAACTATTCACTAACCGATTCAAGGATCGCATTGTATCAATGACACTTGATAAAGAATATGATGTTGCTG
TGGAAGCTATTCGATTGGTTACTCTGATACTTCATGGAAGTGAAGAAGCTCTTTCCAATGAAGACTGTGAAAATGTTTACCACTTGGTGT
ACTCGGCACATCGCCCTGTTGCTGTGGCAGCTGGAGAGTTCCTTCACAAAAAGCTATTTAGCAGACATGACCCACAAGCAGAAGAAGCAT
TAGCAAAGAGGAGGGGAAGAAACAGCCCGAATGGAAACCTCATTAGGATGCTGGTTCTTTTCTTTCTTGAAAGTGAGTTACATGAACATG
CAGCCTACTTGGTGGACAGTTTATGGGAGAGCTCTCAAGAACTGTTGAAAGACTGGGAATGTATGACAGAGTTGCTATTAGAAGAACCTG
TTCAAGGAGAGGAAGCAATGTCTGATCGTCAAGAGAGTGCTCTTATAGAGCTAATGGTTTGTACAATTCGTCAAGCTGCTGAGGCACATC
CTCCAGTGGGAAGGGGTACCGGCAAGAGAGTGCTAACTGCCAAAGAAAGGAAAACTCAAATTGATGATAGAAACAAATTGACTGAACATT
TTATTATTACACTTCCTATGTTACTGTCAAAGTATTCTGCAGATGCAGAGAAGGTAGCAAACTTGCTACAAATCCCACAGTATTTTGATT
TAGAAATCTACAGCACAGGTAGAATGGAAAAGCATCTGGATGCTTTATTAAAACAGATTAAGTTTGTTGTGGAGAAACACGTAGAATCAG
ATGTTCTAGAAGCCTGCAGTAAAACCTATAGTATCTTATGCAGTGAAGAATATACCATCCAGAACAGAGTTGACATAGCTCGAAGCCAGC
TGATTGATGAGTTTGTAGATCGATTCAATCATTCTGTGGAAGACCTATTGCAAGAGGGAGAAGAAGCTGATGATGATGACATTTACAATG
TTCTTTCTACATTAAAGCGGTTAACTTCTTTTCACAATGCACATGATCTCACAAAATGGGATCTCTTTGGTAATTGCTACAGATTATTGA
AGACTGGAATTGAACATGGAGCCATGCCAGAACAGATAGTCGTGCAAGCACTGCAGTGTTCCCATTATTCGATTCTTTGGCAGTTGGTGA
AAATTACTGATGGCTCTCCTTCCAAAGAGGATTTGTTGGTATTGAGGAAAACGGTGAAATCCTTTTTGGCTGTTTGCCAGCAGTGCCTGT
CTAATGTTAATACTCCAGTGAAAGAACAGGCTTTCATGTTACTCTGTGATCTTCTGATGATTTTCAGCCACCAATTAATGACAGGTGGCA
GAGAGGGCCTTCAGCCTTTGGTGTTCAATCCAGATACTGGACTCCAATCTGAACTCCTCAGTTTTGTGATGGATCACGTTTTTATTGACC
AAGACGAGGAGAACCAGAGCATGGAGGGTGATGAAGAAGATGAAGCTAATAAAATTGAGGCCTTACATAAAAGAAGGAATCTACTTGCTG
CTTTCAGCAAACTTATCATTTATGACATTGTTGACATGCATGCAGCTGCAGACATCTTCAAACACTACATGAAGTATTACAATGACTATG
GTGATATTATTAAGGAAACACTGAGTAAAACCAGGCAGATTGATAAAATTCAGTGTGCCAAGACTCTCATTCTCAGTTTGCAACAGTTAT
TTAATGAACTTGTTCAAGAGCAAGGTCCCAACCTAGATAGGACATCTGCCCATGTCAGTGGCATTAAAGAACTGGCACGTCGCTTTGCCC
TTACATTTGGATTGGACCAGATTAAGACACGAGAAGCAGTTGCCACACTTCACAAGGATGGCATAGAGTTTGCATTTAAATACCAAAATC
AGAAAGGACAAGAGTATCCACCTCCTAATCTGGCTTTTCTTGAAGTACTAAGTGAATTTTCTTCTAAACTTCTTCGACAGGACAAAAAGA
CAGTTCATTCATACCTAGAGAAATTCCTTACCGAGCAGATGATGGAAAGGAGGGAGGATGTATGGCTTCCACTCATCTCCTATAGAAATT
CATTAGTCACTGGGGGTGAAGATGATAGAATGTCTGTGAACAGTGGAAGTAGCAGCAGCAAAACCTCATCAGTAAGGAATAAGAAAGGAC
GACCTCCACTTCATAAAAAACGAGTAGAAGATGAGAGTCTGGATAACACATGGCTAAACAGGACTGACACCATGATTCAGACTCCTGGCC
CCCTGCCAGCACCACAACTCACATCCACTGTACTGCGGGAGAACAGTCGGCCCATGGGAGACCAGATTCAAGAACCTGAGTCTGAACATG
GTTCTGAACCAGACTTTTTACACAATCCTCAGATGCAGATCTCTTGGTTAGGCCAGCCGAAGTTAGAAGACTTAAATCGGAAGGACAGAA
CAGGAATGAACTACATGAAAGTGAGAACTGGAGTGAGGCATGCTGTTCGGGGTCTAATGGAGGAAGATGCTGAGCCCATCTTTGAAGATG
TGATGATGTCATCCCGAAGCCAGTTAGAAGATATGAATGAAGAATTTGAGGACACCATGGTTATTGATCTGCCTCCATCAAGAAATCGGC
GAGAGAGAGCTGAGCTAAGGCCAGACTTCTTTGACTCTGCAGCTATCATAGAAGATGATTCAGGATTTGGAATGCCTATGTTCTGAAGTC
TGAAGAAAATTTACAAATCTGGAACTCTATTATTTAGAGCTAGAGGCCTATATACTGTGATAGCTTGTATGGGGAAAAACACTTTTGATG
TGATCTGATTTGTTTTTTAATCAAATGATTAAGGTCAATCCCTTTTTGCAGTGACAGAAGAGGAGCATGTAAATTACCCAAGGGAATGTT
GGTGAATGTCAACTCAGAAAGACTGACCTGAAAATCATTTGTGTCCTACTATTGGACTTATCCCAATACAGATGTGTGTGTTTTTCTGGA
GGGAGGAAGAAATTTTAAATTTTTAAAACAGCTGTCAAGATAAACACTGTTATACACCTGTTTTATGAAAACTCAACATTGAGTAAAAAA
AAACATATTTTTAACTTTATTTTCCTGTTGTACAATTTAAAAACCGTTTTAACATTTTGCCTTTTTATGTTTTAAAAGCTAACCATTTTT
ATTAAACCTATGAGTAAGCAGCTCATCCTAATTGCGAAGAGTGTTTTGGAGTTCACTGGATTTGGTTGACCTTTGTGGAACACAAATAAT
GAAGGAGCAGAACATTGACAAGCTAAGATGAAATTCTGACATAGTACATCTCTGCCAAAAACCACACACCCTCTGTGGATATGGATATGA
ATTCCCAGATTTTATATACTCTTGAATAAAAGGTTTATTTTTATTTATAAGTGGGCATAAAATAAGAAATGTCCATGCAGCCATTTTTCC
AACAGATGCTGTACACCGTTCATTTTATATAGACTAGGGAGATTCAAATACAGTGCATTTTCTATTGGTATTTGTTCTGTGCATTTTTAG
CAACTTCTACCAGCAAATAAAGTATTCTCAGTAAAACGAAAATGATTCTCAAGTTATCAGTTTGCTGTTTTTACCACTTATTTCATGCCC
TGCCAAATTCAAGTTACACAGACTTCCATTTTCTTAAGATAATCAATCATGAAGAAATCCTTTATCAATCATTCAAAAGTAATTTTAAGT
GTAACATAACTGTGTTTACTTCCCATGCACTTAATACCCTTATGCGCTAATTTTGTGAATTAAGTTTACTGATTATAGAAGTATGTGCTG
CATAGAAGTCTGTGCTTAGAGGGTGAAGTTCCTAAGCTTACCTTGAATTACAGCTACATTTCAGTGTTAAATGTGCATATTAAGAATAAT
TCTTTTGGGGAAAGAAATTATGAATCTTCAGGACAGTCTACAATGGTTTAGAGTTACATTCTGCCTAGACTTTTATGACTTGCTGCTATT
GTTTTAAAAACCCCACTTAGTCTCTCTCTTCCTTTCTGATTTCTAAAGTAAGCCTCAGAATTTCCAAACCAATTCATCCACAGCTGTTTC
TGGGCTGGTTTTTAAAGTAGCTGCAACAGAATCATGAGGCTTTCCCTTTTTATCAAATACGAAAAACATTTTTTAAAATTCTGCACACCC
AGTGATCATCTTTTGTGCGGGAAAGCAAGATGATGATGGATGATTTTATTCATCCTTTTAGTAAAGACACAAAACATTTTTCTCAACATT
TGTACAGTTCTGAAAAAAACCTGGTCACCAAAAATATCTTCTCTGCTAATTCAGCAATTCTTGGGCTCCAGTTAGGGGAGCTGGGGCCTC
ACTTTCTCCCAGAATTGTGGGCTTCACTGGAAGTGAAGGTGCAGGAATGACTGGACTGTCCACCCCAGCCCTGCCTGCCTGTGGTTTTGG
CCAGGGAGCAAGCCATGAGGTGCCCTGGCACATGCACAAATTGATCCTTTGCGTGACAGTCTTGTATGGAAAACAGATGCTGACAGAATT
GTAGACTACCATGCCACACAAAAAGGCTAAATATCTACTCCAATGGGTTTCCAGTTCAGTTTGAAGTCAATCAAATTTTTGTATTTTCGG
TGTCTCCTTGATTGGTTTTGCTAGTAATTCTGTAAATTGTACATTTGCAATATGAGGTTTTTTTTCCTTTTGTACAATTTGAAACTGATG

>52675_52675_4_MED1-STAG1_MED1_chr17_37587367_ENST00000394287_STAG1_chr3_136221621_ENST00000383202_length(amino acids)=1249AA_BP=216
MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVSCLETLQKALKVTSLPAMTDRLESIARQNGL
GSHLSASGTECYITSDMFYVEVQLDPAGQLCDVKVAHHGENPVSCPELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSL
EQDLSKMAIMYWKATNAGPLDKILHGSVGYLTPRSGAMKLMTALVNVALNLSIHQDNTQRQYEAERNKMIGKRANERLELLLQKRKELQE
NQDEIENMMNSIFKGIFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTLHDRQGEVRLKCLKALQSLYTNRELFPKLEL
FTNRFKDRIVSMTLDKEYDVAVEAIRLVTLILHGSEEALSNEDCENVYHLVYSAHRPVAVAAGEFLHKKLFSRHDPQAEEALAKRRGRNS
PNGNLIRMLVLFFLESELHEHAAYLVDSLWESSQELLKDWECMTELLLEEPVQGEEAMSDRQESALIELMVCTIRQAAEAHPPVGRGTGK
RVLTAKERKTQIDDRNKLTEHFIITLPMLLSKYSADAEKVANLLQIPQYFDLEIYSTGRMEKHLDALLKQIKFVVEKHVESDVLEACSKT
YSILCSEEYTIQNRVDIARSQLIDEFVDRFNHSVEDLLQEGEEADDDDIYNVLSTLKRLTSFHNAHDLTKWDLFGNCYRLLKTGIEHGAM
PEQIVVQALQCSHYSILWQLVKITDGSPSKEDLLVLRKTVKSFLAVCQQCLSNVNTPVKEQAFMLLCDLLMIFSHQLMTGGREGLQPLVF
NPDTGLQSELLSFVMDHVFIDQDEENQSMEGDEEDEANKIEALHKRRNLLAAFSKLIIYDIVDMHAAADIFKHYMKYYNDYGDIIKETLS
KTRQIDKIQCAKTLILSLQQLFNELVQEQGPNLDRTSAHVSGIKELARRFALTFGLDQIKTREAVATLHKDGIEFAFKYQNQKGQEYPPP
NLAFLEVLSEFSSKLLRQDKKTVHSYLEKFLTEQMMERREDVWLPLISYRNSLVTGGEDDRMSVNSGSSSSKTSSVRNKKGRPPLHKKRV
EDESLDNTWLNRTDTMIQTPGPLPAPQLTSTVLRENSRPMGDQIQEPESEHGSEPDFLHNPQMQISWLGQPKLEDLNRKDRTGMNYMKVR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for MED1-STAG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-917108_212216.333333333333341582.0the Mediator complex
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-918108_212216.33333333333334557.0the Mediator complex


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-91716_590216.333333333333341582.0ESR1
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-917656_1066216.333333333333341582.0ESR1
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-91816_590216.33333333333334557.0ESR1
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-918656_1066216.33333333333334557.0ESR1
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-917681_715216.333333333333341582.0GATA1
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-918681_715216.33333333333334557.0GATA1
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-917622_701216.333333333333341582.0PPARGC1A and THRA
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-918622_701216.33333333333334557.0PPARGC1A and THRA
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-917215_390216.333333333333341582.0the Mediator complex
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-918215_390216.33333333333334557.0the Mediator complex
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-9171_670216.333333333333341582.0the Mediator complex and THRA
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-9181_670216.33333333333334557.0the Mediator complex and THRA
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-917405_644216.333333333333341582.0THRA
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-918405_644216.33333333333334557.0THRA
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-9171249_1421216.333333333333341582.0TP53
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-9181249_1421216.33333333333334557.0TP53
HgeneMED1chr17:37587367chr3:136221621ENST00000300651-917542_789216.333333333333341582.0VDR
HgeneMED1chr17:37587367chr3:136221621ENST00000394287-918542_789216.33333333333334557.0VDR


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for MED1-STAG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for MED1-STAG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource