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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MED29-MYO1D (FusionGDB2 ID:52769)

Fusion Gene Summary for MED29-MYO1D

check button Fusion gene summary
Fusion gene informationFusion gene name: MED29-MYO1D
Fusion gene ID: 52769
HgeneTgene
Gene symbol

MED29

MYO1D

Gene ID

55588

4642

Gene namemediator complex subunit 29myosin ID
SynonymsIXL|MED2PPP1R108|myr4
Cytomap

19q13.2

17q11.2

Type of geneprotein-codingprotein-coding
Descriptionmediator of RNA polymerase II transcription subunit 29intersex-like proteinunconventional myosin-Idmyosin-I gammaprotein phosphatase 1, regulatory subunit 108
Modification date2020031320200313
UniProtAcc

Q9NX70

O94832

Ensembl transtripts involved in fusion geneENST00000315588, ENST00000594368, 
ENST00000599213, 		ENST00000584232, 
ENST00000583621, ENST00000318217, 
ENST00000394649, ENST00000579584, 
Fusion gene scores* DoF score4 X 2 X 3=2428 X 20 X 9=5040
# samples 429
** MAII scorelog2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(29/5040*10)=-4.11929892837234
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MED29 [Title/Abstract] AND MYO1D [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMED29(39884277)-MYO1D(31076024), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneMYO1D

GO:0010923

negative regulation of phosphatase activity

19389623


check buttonFusion gene breakpoints across MED29 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MYO1D (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-C8-A8HP-01AMED29chr19

39884277

-MYO1Dchr17

31076024

-
ChimerDB4BRCATCGA-C8-A8HP-01AMED29chr19

39884277

+MYO1Dchr17

31076024

-


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Fusion Gene ORF analysis for MED29-MYO1D

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000315588ENST00000584232MED29chr19

39884277

+MYO1Dchr17

31076024

-
5CDS-5UTRENST00000594368ENST00000584232MED29chr19

39884277

+MYO1Dchr17

31076024

-
5CDS-5UTRENST00000599213ENST00000584232MED29chr19

39884277

+MYO1Dchr17

31076024

-
5CDS-intronENST00000315588ENST00000583621MED29chr19

39884277

+MYO1Dchr17

31076024

-
5CDS-intronENST00000594368ENST00000583621MED29chr19

39884277

+MYO1Dchr17

31076024

-
5CDS-intronENST00000599213ENST00000583621MED29chr19

39884277

+MYO1Dchr17

31076024

-
In-frameENST00000315588ENST00000318217MED29chr19

39884277

+MYO1Dchr17

31076024

-
In-frameENST00000315588ENST00000394649MED29chr19

39884277

+MYO1Dchr17

31076024

-
In-frameENST00000315588ENST00000579584MED29chr19

39884277

+MYO1Dchr17

31076024

-
In-frameENST00000594368ENST00000318217MED29chr19

39884277

+MYO1Dchr17

31076024

-
In-frameENST00000594368ENST00000394649MED29chr19

39884277

+MYO1Dchr17

31076024

-
In-frameENST00000594368ENST00000579584MED29chr19

39884277

+MYO1Dchr17

31076024

-
In-frameENST00000599213ENST00000318217MED29chr19

39884277

+MYO1Dchr17

31076024

-
In-frameENST00000599213ENST00000394649MED29chr19

39884277

+MYO1Dchr17

31076024

-
In-frameENST00000599213ENST00000579584MED29chr19

39884277

+MYO1Dchr17

31076024

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000315588MED29chr1939884277+ENST00000318217MYO1Dchr1731076024-4263472492025658
ENST00000315588MED29chr1939884277+ENST00000394649MYO1Dchr1731076024-4176472492025658
ENST00000315588MED29chr1939884277+ENST00000579584MYO1Dchr1731076024-2233472491890613
ENST00000594368MED29chr1939884277+ENST00000318217MYO1Dchr1731076024-4181390301943637
ENST00000594368MED29chr1939884277+ENST00000394649MYO1Dchr1731076024-4094390301943637
ENST00000594368MED29chr1939884277+ENST00000579584MYO1Dchr1731076024-2151390301808592
ENST00000599213MED29chr1939884277+ENST00000318217MYO1Dchr1731076024-4178387271940637
ENST00000599213MED29chr1939884277+ENST00000394649MYO1Dchr1731076024-4091387271940637
ENST00000599213MED29chr1939884277+ENST00000579584MYO1Dchr1731076024-2148387271805592

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000315588ENST00000318217MED29chr1939884277+MYO1Dchr1731076024-0.0068857370.9931143
ENST00000315588ENST00000394649MED29chr1939884277+MYO1Dchr1731076024-0.0080353270.9919647
ENST00000315588ENST00000579584MED29chr1939884277+MYO1Dchr1731076024-0.0040544980.9959455
ENST00000594368ENST00000318217MED29chr1939884277+MYO1Dchr1731076024-0.0017565770.99824345
ENST00000594368ENST00000394649MED29chr1939884277+MYO1Dchr1731076024-0.0021243790.9978756
ENST00000594368ENST00000579584MED29chr1939884277+MYO1Dchr1731076024-0.0010345590.9989655
ENST00000599213ENST00000318217MED29chr1939884277+MYO1Dchr1731076024-0.0017608830.99823916
ENST00000599213ENST00000394649MED29chr1939884277+MYO1Dchr1731076024-0.0021292850.9978707
ENST00000599213ENST00000579584MED29chr1939884277+MYO1Dchr1731076024-0.0010377280.9989623

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Fusion Genomic Features for MED29-MYO1D


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MED29-MYO1D


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:39884277/chr17:31076024)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MED29

Q9NX70

MYO1D

O94832

FUNCTION: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. {ECO:0000269|PubMed:15555573}.FUNCTION: Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity). Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity). Required for normal planar cell polarity in ciliated tracheal cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement in the trachea. Required for normal, polarized cilia organization in brain ependymal epithelial cells (By similarity). {ECO:0000250|UniProtKB:F1PRN2, ECO:0000250|UniProtKB:Q63357}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMED29chr19:39884277chr17:31076024ENST00000599213+3429_84120201.0Compositional biasNote=Gln-rich
TgeneMYO1Dchr19:39884277chr17:31076024ENST000003182171022699_7194891007.0DomainIQ 1
TgeneMYO1Dchr19:39884277chr17:31076024ENST000003182171022721_7414891007.0DomainIQ 2
TgeneMYO1Dchr19:39884277chr17:31076024ENST000003182171022812_10054891007.0DomainTH1
TgeneMYO1Dchr19:39884277chr17:31076024ENST000003182171022572_5944891007.0RegionActin-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMYO1Dchr19:39884277chr17:31076024ENST0000031821710229_6954891007.0DomainMyosin motor
TgeneMYO1Dchr19:39884277chr17:31076024ENST000003182171022102_1094891007.0Nucleotide bindingATP


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Fusion Gene Sequence for MED29-MYO1D


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>52769_52769_1_MED29-MYO1D_MED29_chr19_39884277_ENST00000315588_MYO1D_chr17_31076024_ENST00000318217_length(transcript)=4263nt_BP=472nt
AATTGCCTAGGGGGCGGGACTAACTAGCAAACGGGGACTAGAAATAGGGATGCTGAAAAGCAACGGGGAGAGACGCAGTCGTAACGCACT
TCCGGCGGTCTACGCGAGGAAGATGGCTGCATCCCAGCAGCAAGCTTCAGCGGCTTCCTCAGCTGCTGGTGTATCGGGTCCTAGTTCGGC
TGGCGGCCCGGGTCCCCAGCAGCAGCCGCAACCGCCAGCACAACTGGTGGGCCCTGCCCAGAGCGGCCTCCTGCAGCAACAGCAACAGGA
CTTCGATCCTGTGCAGCGTTATAAGATGCTCATCCCGCAGCTGAAGGAGAGTCTACAGACCTTGATGAAGGTTGCGGCCCAAAACTTGAT
TCAGAACACTAACATCGACAATGGACAAAAGAGCAGTGATGGACCCATACAGCGCTTTGACAAGTGCCTGGAAGAGTTCTATGCACTCTG
TGACCAGCTGGAGCTGTGCCTGCTCTGTGCCTCAGACAAAATTCTGGAGTTTGATCGAGATTTTCGAATTCGACATTATGCAGGCGATGT
AGTCTATTCTGTCATTGGTTTTATTGACAAAAATAAAGATACTTTATTTCAAGATTTCAAGCGCCTTATGTATAACAGTTCAAATCCTGT
GCTCAAGAATATGTGGCCTGAAGGCAAACTGAGCATTACAGAGGTGACCAAGCGACCTCTGACTGCTGCTACCTTGTTTAAGAATTCTAT
GATTGCTCTAGTAGACAACCTTGCATCAAAGGAACCATATTACGTTCGTTGCATCAAACCCAATGACAAGAAATCTCCACAGATATTTGA
TGATGAACGCTGCCGGCACCAAGTAGAATATCTTGGACTACTGGAAAATGTGAGAGTGCGTCGGGCAGGATTTGCCTTCCGCCAGACATA
CGAGAAGTTTCTTCACAGGTATAAGATGATCTCTGAATTCACCTGGCCCAACCATGACCTTCCTTCAGACAAAGAGGCTGTCAAGAAACT
AATTGAACGGTGTGGTTTTCAGGATGATGTAGCTTATGGGAAGACCAAAATTTTCATTCGAACACCCCGAACATTGTTTACCTTGGAAGA
ACTCCGTGCCCAGATGCTCATAAGGATTGTCCTCTTTCTACAAAAGGTGTGGCGGGGCACCCTGGCCCGCATGCGGTACAAAAGAACCAA
GGCAGCTCTGACAATAATCAGGTACTACCGGCGCTACAAAGTGAAGTCGTACATCCACGAGGTGGCCAGACGCTTCCATGGCGTCAAGAC
CATGCGAGACTACGGGAAGCACGTGAAGTGGCCAAGCCCTCCTAAAGTTCTTCGCCGTTTTGAGGAGGCCCTGCAGACGATTTTCAATAG
ATGGAGAGCATCCCAGCTCATCAAGAGCATTCCGGCCTCAGACCTGCCCCAGGTCAGGGCAAAGGTTGCAGCCGTGGAAATGTTGAAGGG
TCAAAGGGCTGACCTCGGGCTCCAGAGGGCCTGGGAGGGCAACTATCTTGCTTCAAAGCCAGATACACCTCAGACCTCAGGCACTTTTGT
CCCTGTTGCTAATGAATTGAAACGGAAGGACAAATACATGAATGTCCTCTTTTCCTGTCACGTCCGTAAGGTAAATCGATTTAGTAAGGT
GGAAGACAGAGCAATTTTTGTCACTGACCGTCACCTGTATAAAATGGATCCCACTAAACAGTACAAGGTGATGAAGACTATCCCTCTATA
CAATTTGACTGGTCTGAGTGTCTCCAATGGAAAGGACCAACTTGTAGTGTTCCATACGAAAGACAACAAAGACCTCATTGTCTGCCTCTT
CAGCAAACAGCCAACCCATGAGAGTCGAATTGGAGAACTTGTTGGAGTGCTGGTGAATCATTTCAAGAGTGAGAAGCGCCACCTTCAAGT
GAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCCCCAGCCCGACTT
CACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCCACACTCCGAGTC
CTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCCCGCCCCTGTAAG
ATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAAGACCCTGGTGCC
CCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGATGCCCCGTGGCCA
GGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCCACTCTGCGGGAG
CCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCGGACCCACCCCAA
CCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGTGGCAGGAGCGGA
ACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACCAGGGCCTCTGAC
CACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTTATAGATACTTTC
ACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGCCAGGGTGAGGGC
AGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGTCAAGACACGGGA
TGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGCCCTCTACACGGC
CCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTATGCTTCAGGGGC
CTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCCCATGCGGTGAGA
GGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCAGAGGTGCAAGAG
AGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACCAAGTGCCTGTGT
GCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCTGCTTCCCAAAAA
TTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTGGTCAGCTGCCTG
CACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCATCTAACTGGAACT
TCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCAAAACAGATCATG
CCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATGGTGCCTTGGGCC
CCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTATGTGGCAACTGC
AAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTAGACAATGAGGGG
GTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCTAAAGCATATTTT
GATTTGCCATCAAGAGCAATAAAGCATTAAATCTTATTTTTAAAGGTGTTCTGCTTATCTGTCACTGAAAACTTGGTGAAATTTTTGCTT

>52769_52769_1_MED29-MYO1D_MED29_chr19_39884277_ENST00000315588_MYO1D_chr17_31076024_ENST00000318217_length(amino acids)=658AA_BP=141
MLKSNGERRSRNALPAVYARKMAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKE
SLQTLMKVAAQNLIQNTNIDNGQKSSDGPIQRFDKCLEEFYALCDQLELCLLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLF
QDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLEN
VRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKV
WRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLP
QVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMD
PTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLHGKKCT

--------------------------------------------------------------
>52769_52769_2_MED29-MYO1D_MED29_chr19_39884277_ENST00000315588_MYO1D_chr17_31076024_ENST00000394649_length(transcript)=4176nt_BP=472nt
AATTGCCTAGGGGGCGGGACTAACTAGCAAACGGGGACTAGAAATAGGGATGCTGAAAAGCAACGGGGAGAGACGCAGTCGTAACGCACT
TCCGGCGGTCTACGCGAGGAAGATGGCTGCATCCCAGCAGCAAGCTTCAGCGGCTTCCTCAGCTGCTGGTGTATCGGGTCCTAGTTCGGC
TGGCGGCCCGGGTCCCCAGCAGCAGCCGCAACCGCCAGCACAACTGGTGGGCCCTGCCCAGAGCGGCCTCCTGCAGCAACAGCAACAGGA
CTTCGATCCTGTGCAGCGTTATAAGATGCTCATCCCGCAGCTGAAGGAGAGTCTACAGACCTTGATGAAGGTTGCGGCCCAAAACTTGAT
TCAGAACACTAACATCGACAATGGACAAAAGAGCAGTGATGGACCCATACAGCGCTTTGACAAGTGCCTGGAAGAGTTCTATGCACTCTG
TGACCAGCTGGAGCTGTGCCTGCTCTGTGCCTCAGACAAAATTCTGGAGTTTGATCGAGATTTTCGAATTCGACATTATGCAGGCGATGT
AGTCTATTCTGTCATTGGTTTTATTGACAAAAATAAAGATACTTTATTTCAAGATTTCAAGCGCCTTATGTATAACAGTTCAAATCCTGT
GCTCAAGAATATGTGGCCTGAAGGCAAACTGAGCATTACAGAGGTGACCAAGCGACCTCTGACTGCTGCTACCTTGTTTAAGAATTCTAT
GATTGCTCTAGTAGACAACCTTGCATCAAAGGAACCATATTACGTTCGTTGCATCAAACCCAATGACAAGAAATCTCCACAGATATTTGA
TGATGAACGCTGCCGGCACCAAGTAGAATATCTTGGACTACTGGAAAATGTGAGAGTGCGTCGGGCAGGATTTGCCTTCCGCCAGACATA
CGAGAAGTTTCTTCACAGGTATAAGATGATCTCTGAATTCACCTGGCCCAACCATGACCTTCCTTCAGACAAAGAGGCTGTCAAGAAACT
AATTGAACGGTGTGGTTTTCAGGATGATGTAGCTTATGGGAAGACCAAAATTTTCATTCGAACACCCCGAACATTGTTTACCTTGGAAGA
ACTCCGTGCCCAGATGCTCATAAGGATTGTCCTCTTTCTACAAAAGGTGTGGCGGGGCACCCTGGCCCGCATGCGGTACAAAAGAACCAA
GGCAGCTCTGACAATAATCAGGTACTACCGGCGCTACAAAGTGAAGTCGTACATCCACGAGGTGGCCAGACGCTTCCATGGCGTCAAGAC
CATGCGAGACTACGGGAAGCACGTGAAGTGGCCAAGCCCTCCTAAAGTTCTTCGCCGTTTTGAGGAGGCCCTGCAGACGATTTTCAATAG
ATGGAGAGCATCCCAGCTCATCAAGAGCATTCCGGCCTCAGACCTGCCCCAGGTCAGGGCAAAGGTTGCAGCCGTGGAAATGTTGAAGGG
TCAAAGGGCTGACCTCGGGCTCCAGAGGGCCTGGGAGGGCAACTATCTTGCTTCAAAGCCAGATACACCTCAGACCTCAGGCACTTTTGT
CCCTGTTGCTAATGAATTGAAACGGAAGGACAAATACATGAATGTCCTCTTTTCCTGTCACGTCCGTAAGGTAAATCGATTTAGTAAGGT
GGAAGACAGAGCAATTTTTGTCACTGACCGTCACCTGTATAAAATGGATCCCACTAAACAGTACAAGGTGATGAAGACTATCCCTCTATA
CAATTTGACTGGTCTGAGTGTCTCCAATGGAAAGGACCAACTTGTAGTGTTCCATACGAAAGACAACAAAGACCTCATTGTCTGCCTCTT
CAGCAAACAGCCAACCCATGAGAGTCGAATTGGAGAACTTGTTGGAGTGCTGGTGAATCATTTCAAGAGTGAGAAGCGCCACCTTCAAGT
GAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCCCCAGCCCGACTT
CACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCCACACTCCGAGTC
CTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCCCGCCCCTGTAAG
ATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAAGACCCTGGTGCC
CCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGATGCCCCGTGGCCA
GGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCCACTCTGCGGGAG
CCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCGGACCCACCCCAA
CCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGTGGCAGGAGCGGA
ACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACCAGGGCCTCTGAC
CACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTTATAGATACTTTC
ACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGCCAGGGTGAGGGC
AGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGTCAAGACACGGGA
TGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGCCCTCTACACGGC
CCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTATGCTTCAGGGGC
CTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCCCATGCGGTGAGA
GGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCAGAGGTGCAAGAG
AGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACCAAGTGCCTGTGT
GCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCTGCTTCCCAAAAA
TTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTGGTCAGCTGCCTG
CACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCATCTAACTGGAACT
TCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCAAAACAGATCATG
CCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATGGTGCCTTGGGCC
CCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTATGTGGCAACTGC
AAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTAGACAATGAGGGG
GTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCTAAAGCATATTTT

>52769_52769_2_MED29-MYO1D_MED29_chr19_39884277_ENST00000315588_MYO1D_chr17_31076024_ENST00000394649_length(amino acids)=658AA_BP=141
MLKSNGERRSRNALPAVYARKMAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKE
SLQTLMKVAAQNLIQNTNIDNGQKSSDGPIQRFDKCLEEFYALCDQLELCLLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLF
QDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLEN
VRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKV
WRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLP
QVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMD
PTKQYKVMKTIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLHGKKCT

--------------------------------------------------------------
>52769_52769_3_MED29-MYO1D_MED29_chr19_39884277_ENST00000315588_MYO1D_chr17_31076024_ENST00000579584_length(transcript)=2233nt_BP=472nt
AATTGCCTAGGGGGCGGGACTAACTAGCAAACGGGGACTAGAAATAGGGATGCTGAAAAGCAACGGGGAGAGACGCAGTCGTAACGCACT
TCCGGCGGTCTACGCGAGGAAGATGGCTGCATCCCAGCAGCAAGCTTCAGCGGCTTCCTCAGCTGCTGGTGTATCGGGTCCTAGTTCGGC
TGGCGGCCCGGGTCCCCAGCAGCAGCCGCAACCGCCAGCACAACTGGTGGGCCCTGCCCAGAGCGGCCTCCTGCAGCAACAGCAACAGGA
CTTCGATCCTGTGCAGCGTTATAAGATGCTCATCCCGCAGCTGAAGGAGAGTCTACAGACCTTGATGAAGGTTGCGGCCCAAAACTTGAT
TCAGAACACTAACATCGACAATGGACAAAAGAGCAGTGATGGACCCATACAGCGCTTTGACAAGTGCCTGGAAGAGTTCTATGCACTCTG
TGACCAGCTGGAGCTGTGCCTGCTCTGTGCCTCAGACAAAATTCTGGAGTTTGATCGAGATTTTCGAATTCGACATTATGCAGGCGATGT
AGTCTATTCTGTCATTGGTTTTATTGACAAAAATAAAGATACTTTATTTCAAGATTTCAAGCGCCTTATGTATAACAGTTCAAATCCTGT
GCTCAAGAATATGTGGCCTGAAGGCAAACTGAGCATTACAGAGGTGACCAAGCGACCTCTGACTGCTGCTACCTTGTTTAAGAATTCTAT
GATTGCTCTAGTAGACAACCTTGCATCAAAGGAACCATATTACGTTCGTTGCATCAAACCCAATGACAAGAAATCTCCACAGATATTTGA
TGATGAACGCTGCCGGCACCAAGTAGAATATCTTGGACTACTGGAAAATGTGAGAGTGCGTCGGGCAGGATTTGCCTTCCGCCAGACATA
CGAGAAGTTTCTTCACAGGTATAAGATGATCTCTGAATTCACCTGGCCCAACCATGACCTTCCTTCAGACAAAGAGGCTGTCAAGAAACT
AATTGAACGGTGTGGTTTTCAGGATGATGTAGCTTATGGGAAGACCAAAATTTTCATTCGAACACCCCGAACATTGTTTACCTTGGAAGA
ACTCCGTGCCCAGATGCTCATAAGGATTGTCCTCTTTCTACAAAAGGTGTGGCGGGGCACCCTGGCCCGCATGCGGTACAAAAGAACCAA
GGCAGCTCTGACAATAATCAGGTACTACCGGCGCTACAAAGTGAAGTCGTACATCCACGAGGTGGCCAGACGCTTCCATGGCGTCAAGAC
CATGCGAGACTACGGGAAGCACGTGAAGTGGCCAAGCCCTCCTAAAGTTCTTCGCCGTTTTGAGGAGGCCCTGCAGACGATTTTCAATAG
ATGGAGAGCATCCCAGCTCATCAAGAGCATTCCGGCCTCAGACCTGCCCCAGGTCAGGGCAAAGGTTGCAGCCGTGGAAATGTTGAAGGG
TCAAAGGGCTGACCTCGGGCTCCAGAGGGCCTGGGAGGGCAACTATCTTGCTTCAAAGCCAGATACACCTCAGACCTCAGGCACTTTTGT
CCCTGTTGCTAATGAATTGAAACGGAAGGACAAATACATGAATGTCCTCTTTTCCTGTCACGTCCGTAAGGTAAATCGATTTAGTAAGGT
GGAAGACAGAGCAATTTTTGTCACTGACCGTCACCTGTATAAAATGGATCCCACTAAACAGTACAAGGTGATGAAGACTATCCCTCTATA
CAATTTGACTGGTCTGAGTGTCTCCAATGGAAAGGACCAACTTGTAGTGTTCCATACGAAAGACAACAAAGACCTCATTGTCTGCCTCTT
CAGCAAACAGCCAACCCATGAGAGTCGAATTGGAGAACTTGTTGGAGTGCTGGTGAATCATTTCAAGAGAAACCATCTGCTTATACTCTG
AATAAAATTCAAGAAAGCATAGATTCTACATAAACAGGCCCAAGATTACATGGCAAACTGAGATGAAGAGGATGCTGGCTGAGAAACAAA
CAAAAGTGTTCAATTATTTGAATGAAGTAAGGAAAGATATTTTAAAATGTAAATCAACATTAAAATCTGAAAATGGCACAGTTGATATTG
CAGAAAATAGAATTGATGTGAAAGGAAAGTTTGAAGTCTCTCAGTGTGCAGAATTTACTGTTATAATGGGCAACATGTTAACTTTCTTAG

>52769_52769_3_MED29-MYO1D_MED29_chr19_39884277_ENST00000315588_MYO1D_chr17_31076024_ENST00000579584_length(amino acids)=613AA_BP=141
MLKSNGERRSRNALPAVYARKMAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKE
SLQTLMKVAAQNLIQNTNIDNGQKSSDGPIQRFDKCLEEFYALCDQLELCLLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLF
QDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLEN
VRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKV
WRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLP
QVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMD

--------------------------------------------------------------
>52769_52769_4_MED29-MYO1D_MED29_chr19_39884277_ENST00000594368_MYO1D_chr17_31076024_ENST00000318217_length(transcript)=4181nt_BP=390nt
AACGCACTTCCGGCGGTCTACGCGAGGAAGATGGCTGCATCCCAGCAGCAAGCTTCAGCGGCTTCCTCAGCTGCTGGTGTATCGGGTCCT
AGTTCGGCTGGCGGCCCGGGTCCCCAGCAGCAGCCGCAACCGCCAGCACAACTGGTGGGCCCTGCCCAGAGCGGCCTCCTGCAGCAACAG
CAACAGGACTTCGATCCTGTGCAGCGTTATAAGATGCTCATCCCGCAGCTGAAGGAGAGTCTACAGACCTTGATGAAGGTTGCGGCCCAA
AACTTGATTCAGAACACTAACATCGACAATGGACAAAAGAGCAGTGATGGACCCATACAGCGCTTTGACAAGTGCCTGGAAGAGTTCTAT
GCACTCTGTGACCAGCTGGAGCTGTGCCTGCTCTGTGCCTCAGACAAAATTCTGGAGTTTGATCGAGATTTTCGAATTCGACATTATGCA
GGCGATGTAGTCTATTCTGTCATTGGTTTTATTGACAAAAATAAAGATACTTTATTTCAAGATTTCAAGCGCCTTATGTATAACAGTTCA
AATCCTGTGCTCAAGAATATGTGGCCTGAAGGCAAACTGAGCATTACAGAGGTGACCAAGCGACCTCTGACTGCTGCTACCTTGTTTAAG
AATTCTATGATTGCTCTAGTAGACAACCTTGCATCAAAGGAACCATATTACGTTCGTTGCATCAAACCCAATGACAAGAAATCTCCACAG
ATATTTGATGATGAACGCTGCCGGCACCAAGTAGAATATCTTGGACTACTGGAAAATGTGAGAGTGCGTCGGGCAGGATTTGCCTTCCGC
CAGACATACGAGAAGTTTCTTCACAGGTATAAGATGATCTCTGAATTCACCTGGCCCAACCATGACCTTCCTTCAGACAAAGAGGCTGTC
AAGAAACTAATTGAACGGTGTGGTTTTCAGGATGATGTAGCTTATGGGAAGACCAAAATTTTCATTCGAACACCCCGAACATTGTTTACC
TTGGAAGAACTCCGTGCCCAGATGCTCATAAGGATTGTCCTCTTTCTACAAAAGGTGTGGCGGGGCACCCTGGCCCGCATGCGGTACAAA
AGAACCAAGGCAGCTCTGACAATAATCAGGTACTACCGGCGCTACAAAGTGAAGTCGTACATCCACGAGGTGGCCAGACGCTTCCATGGC
GTCAAGACCATGCGAGACTACGGGAAGCACGTGAAGTGGCCAAGCCCTCCTAAAGTTCTTCGCCGTTTTGAGGAGGCCCTGCAGACGATT
TTCAATAGATGGAGAGCATCCCAGCTCATCAAGAGCATTCCGGCCTCAGACCTGCCCCAGGTCAGGGCAAAGGTTGCAGCCGTGGAAATG
TTGAAGGGTCAAAGGGCTGACCTCGGGCTCCAGAGGGCCTGGGAGGGCAACTATCTTGCTTCAAAGCCAGATACACCTCAGACCTCAGGC
ACTTTTGTCCCTGTTGCTAATGAATTGAAACGGAAGGACAAATACATGAATGTCCTCTTTTCCTGTCACGTCCGTAAGGTAAATCGATTT
AGTAAGGTGGAAGACAGAGCAATTTTTGTCACTGACCGTCACCTGTATAAAATGGATCCCACTAAACAGTACAAGGTGATGAAGACTATC
CCTCTATACAATTTGACTGGTCTGAGTGTCTCCAATGGAAAGGACCAACTTGTAGTGTTCCATACGAAAGACAACAAAGACCTCATTGTC
TGCCTCTTCAGCAAACAGCCAACCCATGAGAGTCGAATTGGAGAACTTGTTGGAGTGCTGGTGAATCATTTCAAGAGTGAGAAGCGCCAC
CTTCAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCCCCAG
CCCGACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCCACAC
TCCGAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCCCGCC
CCTGTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAAGACC
CTGGTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGATGCCC
CGTGGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCCACTC
TGCGGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCGGACC
CACCCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGTGGCA
GGAGCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACCAGGG
CCTCTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTTATAG
ATACTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGCCAGG
GTGAGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGTCAAG
ACACGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGCCCTC
TACACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTATGCT
TCAGGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCCCATG
CGGTGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCAGAGG
TGCAAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACCAAGT
GCCTGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCTGCTT
CCCAAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTGGTCA
GCTGCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCATCTAA
CTGGAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCAAAAC
AGATCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATGGTGC
CTTGGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTATGTG
GCAACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTAGACA
ATGAGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCTAAAG
CATATTTTGATTTGCCATCAAGAGCAATAAAGCATTAAATCTTATTTTTAAAGGTGTTCTGCTTATCTGTCACTGAAAACTTGGTGAAAT

>52769_52769_4_MED29-MYO1D_MED29_chr19_39884277_ENST00000594368_MYO1D_chr17_31076024_ENST00000318217_length(amino acids)=637AA_BP=120
MAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDN
GQKSSDGPIQRFDKCLEEFYALCDQLELCLLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPE
GKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRY
KMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKRTKAALTIIR
YYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGL
QRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSV
SNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGF

--------------------------------------------------------------
>52769_52769_5_MED29-MYO1D_MED29_chr19_39884277_ENST00000594368_MYO1D_chr17_31076024_ENST00000394649_length(transcript)=4094nt_BP=390nt
AACGCACTTCCGGCGGTCTACGCGAGGAAGATGGCTGCATCCCAGCAGCAAGCTTCAGCGGCTTCCTCAGCTGCTGGTGTATCGGGTCCT
AGTTCGGCTGGCGGCCCGGGTCCCCAGCAGCAGCCGCAACCGCCAGCACAACTGGTGGGCCCTGCCCAGAGCGGCCTCCTGCAGCAACAG
CAACAGGACTTCGATCCTGTGCAGCGTTATAAGATGCTCATCCCGCAGCTGAAGGAGAGTCTACAGACCTTGATGAAGGTTGCGGCCCAA
AACTTGATTCAGAACACTAACATCGACAATGGACAAAAGAGCAGTGATGGACCCATACAGCGCTTTGACAAGTGCCTGGAAGAGTTCTAT
GCACTCTGTGACCAGCTGGAGCTGTGCCTGCTCTGTGCCTCAGACAAAATTCTGGAGTTTGATCGAGATTTTCGAATTCGACATTATGCA
GGCGATGTAGTCTATTCTGTCATTGGTTTTATTGACAAAAATAAAGATACTTTATTTCAAGATTTCAAGCGCCTTATGTATAACAGTTCA
AATCCTGTGCTCAAGAATATGTGGCCTGAAGGCAAACTGAGCATTACAGAGGTGACCAAGCGACCTCTGACTGCTGCTACCTTGTTTAAG
AATTCTATGATTGCTCTAGTAGACAACCTTGCATCAAAGGAACCATATTACGTTCGTTGCATCAAACCCAATGACAAGAAATCTCCACAG
ATATTTGATGATGAACGCTGCCGGCACCAAGTAGAATATCTTGGACTACTGGAAAATGTGAGAGTGCGTCGGGCAGGATTTGCCTTCCGC
CAGACATACGAGAAGTTTCTTCACAGGTATAAGATGATCTCTGAATTCACCTGGCCCAACCATGACCTTCCTTCAGACAAAGAGGCTGTC
AAGAAACTAATTGAACGGTGTGGTTTTCAGGATGATGTAGCTTATGGGAAGACCAAAATTTTCATTCGAACACCCCGAACATTGTTTACC
TTGGAAGAACTCCGTGCCCAGATGCTCATAAGGATTGTCCTCTTTCTACAAAAGGTGTGGCGGGGCACCCTGGCCCGCATGCGGTACAAA
AGAACCAAGGCAGCTCTGACAATAATCAGGTACTACCGGCGCTACAAAGTGAAGTCGTACATCCACGAGGTGGCCAGACGCTTCCATGGC
GTCAAGACCATGCGAGACTACGGGAAGCACGTGAAGTGGCCAAGCCCTCCTAAAGTTCTTCGCCGTTTTGAGGAGGCCCTGCAGACGATT
TTCAATAGATGGAGAGCATCCCAGCTCATCAAGAGCATTCCGGCCTCAGACCTGCCCCAGGTCAGGGCAAAGGTTGCAGCCGTGGAAATG
TTGAAGGGTCAAAGGGCTGACCTCGGGCTCCAGAGGGCCTGGGAGGGCAACTATCTTGCTTCAAAGCCAGATACACCTCAGACCTCAGGC
ACTTTTGTCCCTGTTGCTAATGAATTGAAACGGAAGGACAAATACATGAATGTCCTCTTTTCCTGTCACGTCCGTAAGGTAAATCGATTT
AGTAAGGTGGAAGACAGAGCAATTTTTGTCACTGACCGTCACCTGTATAAAATGGATCCCACTAAACAGTACAAGGTGATGAAGACTATC
CCTCTATACAATTTGACTGGTCTGAGTGTCTCCAATGGAAAGGACCAACTTGTAGTGTTCCATACGAAAGACAACAAAGACCTCATTGTC
TGCCTCTTCAGCAAACAGCCAACCCATGAGAGTCGAATTGGAGAACTTGTTGGAGTGCTGGTGAATCATTTCAAGAGTGAGAAGCGCCAC
CTTCAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCCCCAG
CCCGACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCCACAC
TCCGAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCCCGCC
CCTGTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAAGACC
CTGGTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGATGCCC
CGTGGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCCACTC
TGCGGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCGGACC
CACCCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGTGGCA
GGAGCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACCAGGG
CCTCTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTTATAG
ATACTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGCCAGG
GTGAGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGTCAAG
ACACGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGCCCTC
TACACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTATGCT
TCAGGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCCCATG
CGGTGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCAGAGG
TGCAAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACCAAGT
GCCTGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCTGCTT
CCCAAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTGGTCA
GCTGCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCATCTAA
CTGGAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCAAAAC
AGATCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATGGTGC
CTTGGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTATGTG
GCAACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTAGACA
ATGAGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCTAAAG

>52769_52769_5_MED29-MYO1D_MED29_chr19_39884277_ENST00000594368_MYO1D_chr17_31076024_ENST00000394649_length(amino acids)=637AA_BP=120
MAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDN
GQKSSDGPIQRFDKCLEEFYALCDQLELCLLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPE
GKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRY
KMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKRTKAALTIIR
YYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGL
QRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSV
SNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGF

--------------------------------------------------------------
>52769_52769_6_MED29-MYO1D_MED29_chr19_39884277_ENST00000594368_MYO1D_chr17_31076024_ENST00000579584_length(transcript)=2151nt_BP=390nt
AACGCACTTCCGGCGGTCTACGCGAGGAAGATGGCTGCATCCCAGCAGCAAGCTTCAGCGGCTTCCTCAGCTGCTGGTGTATCGGGTCCT
AGTTCGGCTGGCGGCCCGGGTCCCCAGCAGCAGCCGCAACCGCCAGCACAACTGGTGGGCCCTGCCCAGAGCGGCCTCCTGCAGCAACAG
CAACAGGACTTCGATCCTGTGCAGCGTTATAAGATGCTCATCCCGCAGCTGAAGGAGAGTCTACAGACCTTGATGAAGGTTGCGGCCCAA
AACTTGATTCAGAACACTAACATCGACAATGGACAAAAGAGCAGTGATGGACCCATACAGCGCTTTGACAAGTGCCTGGAAGAGTTCTAT
GCACTCTGTGACCAGCTGGAGCTGTGCCTGCTCTGTGCCTCAGACAAAATTCTGGAGTTTGATCGAGATTTTCGAATTCGACATTATGCA
GGCGATGTAGTCTATTCTGTCATTGGTTTTATTGACAAAAATAAAGATACTTTATTTCAAGATTTCAAGCGCCTTATGTATAACAGTTCA
AATCCTGTGCTCAAGAATATGTGGCCTGAAGGCAAACTGAGCATTACAGAGGTGACCAAGCGACCTCTGACTGCTGCTACCTTGTTTAAG
AATTCTATGATTGCTCTAGTAGACAACCTTGCATCAAAGGAACCATATTACGTTCGTTGCATCAAACCCAATGACAAGAAATCTCCACAG
ATATTTGATGATGAACGCTGCCGGCACCAAGTAGAATATCTTGGACTACTGGAAAATGTGAGAGTGCGTCGGGCAGGATTTGCCTTCCGC
CAGACATACGAGAAGTTTCTTCACAGGTATAAGATGATCTCTGAATTCACCTGGCCCAACCATGACCTTCCTTCAGACAAAGAGGCTGTC
AAGAAACTAATTGAACGGTGTGGTTTTCAGGATGATGTAGCTTATGGGAAGACCAAAATTTTCATTCGAACACCCCGAACATTGTTTACC
TTGGAAGAACTCCGTGCCCAGATGCTCATAAGGATTGTCCTCTTTCTACAAAAGGTGTGGCGGGGCACCCTGGCCCGCATGCGGTACAAA
AGAACCAAGGCAGCTCTGACAATAATCAGGTACTACCGGCGCTACAAAGTGAAGTCGTACATCCACGAGGTGGCCAGACGCTTCCATGGC
GTCAAGACCATGCGAGACTACGGGAAGCACGTGAAGTGGCCAAGCCCTCCTAAAGTTCTTCGCCGTTTTGAGGAGGCCCTGCAGACGATT
TTCAATAGATGGAGAGCATCCCAGCTCATCAAGAGCATTCCGGCCTCAGACCTGCCCCAGGTCAGGGCAAAGGTTGCAGCCGTGGAAATG
TTGAAGGGTCAAAGGGCTGACCTCGGGCTCCAGAGGGCCTGGGAGGGCAACTATCTTGCTTCAAAGCCAGATACACCTCAGACCTCAGGC
ACTTTTGTCCCTGTTGCTAATGAATTGAAACGGAAGGACAAATACATGAATGTCCTCTTTTCCTGTCACGTCCGTAAGGTAAATCGATTT
AGTAAGGTGGAAGACAGAGCAATTTTTGTCACTGACCGTCACCTGTATAAAATGGATCCCACTAAACAGTACAAGGTGATGAAGACTATC
CCTCTATACAATTTGACTGGTCTGAGTGTCTCCAATGGAAAGGACCAACTTGTAGTGTTCCATACGAAAGACAACAAAGACCTCATTGTC
TGCCTCTTCAGCAAACAGCCAACCCATGAGAGTCGAATTGGAGAACTTGTTGGAGTGCTGGTGAATCATTTCAAGAGAAACCATCTGCTT
ATACTCTGAATAAAATTCAAGAAAGCATAGATTCTACATAAACAGGCCCAAGATTACATGGCAAACTGAGATGAAGAGGATGCTGGCTGA
GAAACAAACAAAAGTGTTCAATTATTTGAATGAAGTAAGGAAAGATATTTTAAAATGTAAATCAACATTAAAATCTGAAAATGGCACAGT
TGATATTGCAGAAAATAGAATTGATGTGAAAGGAAAGTTTGAAGTCTCTCAGTGTGCAGAATTTACTGTTATAATGGGCAACATGTTAAC

>52769_52769_6_MED29-MYO1D_MED29_chr19_39884277_ENST00000594368_MYO1D_chr17_31076024_ENST00000579584_length(amino acids)=592AA_BP=120
MAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDN
GQKSSDGPIQRFDKCLEEFYALCDQLELCLLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPE
GKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRY
KMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKRTKAALTIIR
YYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGL
QRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSV

--------------------------------------------------------------
>52769_52769_7_MED29-MYO1D_MED29_chr19_39884277_ENST00000599213_MYO1D_chr17_31076024_ENST00000318217_length(transcript)=4178nt_BP=387nt
GCACTTCCGGCGGTCTACGCGAGGAAGATGGCTGCATCCCAGCAGCAAGCTTCAGCGGCTTCCTCAGCTGCTGGTGTATCGGGTCCTAGT
TCGGCTGGCGGCCCGGGTCCCCAGCAGCAGCCGCAACCGCCAGCACAACTGGTGGGCCCTGCCCAGAGCGGCCTCCTGCAGCAACAGCAA
CAGGACTTCGATCCTGTGCAGCGTTATAAGATGCTCATCCCGCAGCTGAAGGAGAGTCTACAGACCTTGATGAAGGTTGCGGCCCAAAAC
TTGATTCAGAACACTAACATCGACAATGGACAAAAGAGCAGTGATGGACCCATACAGCGCTTTGACAAGTGCCTGGAAGAGTTCTATGCA
CTCTGTGACCAGCTGGAGCTGTGCCTGCTCTGTGCCTCAGACAAAATTCTGGAGTTTGATCGAGATTTTCGAATTCGACATTATGCAGGC
GATGTAGTCTATTCTGTCATTGGTTTTATTGACAAAAATAAAGATACTTTATTTCAAGATTTCAAGCGCCTTATGTATAACAGTTCAAAT
CCTGTGCTCAAGAATATGTGGCCTGAAGGCAAACTGAGCATTACAGAGGTGACCAAGCGACCTCTGACTGCTGCTACCTTGTTTAAGAAT
TCTATGATTGCTCTAGTAGACAACCTTGCATCAAAGGAACCATATTACGTTCGTTGCATCAAACCCAATGACAAGAAATCTCCACAGATA
TTTGATGATGAACGCTGCCGGCACCAAGTAGAATATCTTGGACTACTGGAAAATGTGAGAGTGCGTCGGGCAGGATTTGCCTTCCGCCAG
ACATACGAGAAGTTTCTTCACAGGTATAAGATGATCTCTGAATTCACCTGGCCCAACCATGACCTTCCTTCAGACAAAGAGGCTGTCAAG
AAACTAATTGAACGGTGTGGTTTTCAGGATGATGTAGCTTATGGGAAGACCAAAATTTTCATTCGAACACCCCGAACATTGTTTACCTTG
GAAGAACTCCGTGCCCAGATGCTCATAAGGATTGTCCTCTTTCTACAAAAGGTGTGGCGGGGCACCCTGGCCCGCATGCGGTACAAAAGA
ACCAAGGCAGCTCTGACAATAATCAGGTACTACCGGCGCTACAAAGTGAAGTCGTACATCCACGAGGTGGCCAGACGCTTCCATGGCGTC
AAGACCATGCGAGACTACGGGAAGCACGTGAAGTGGCCAAGCCCTCCTAAAGTTCTTCGCCGTTTTGAGGAGGCCCTGCAGACGATTTTC
AATAGATGGAGAGCATCCCAGCTCATCAAGAGCATTCCGGCCTCAGACCTGCCCCAGGTCAGGGCAAAGGTTGCAGCCGTGGAAATGTTG
AAGGGTCAAAGGGCTGACCTCGGGCTCCAGAGGGCCTGGGAGGGCAACTATCTTGCTTCAAAGCCAGATACACCTCAGACCTCAGGCACT
TTTGTCCCTGTTGCTAATGAATTGAAACGGAAGGACAAATACATGAATGTCCTCTTTTCCTGTCACGTCCGTAAGGTAAATCGATTTAGT
AAGGTGGAAGACAGAGCAATTTTTGTCACTGACCGTCACCTGTATAAAATGGATCCCACTAAACAGTACAAGGTGATGAAGACTATCCCT
CTATACAATTTGACTGGTCTGAGTGTCTCCAATGGAAAGGACCAACTTGTAGTGTTCCATACGAAAGACAACAAAGACCTCATTGTCTGC
CTCTTCAGCAAACAGCCAACCCATGAGAGTCGAATTGGAGAACTTGTTGGAGTGCTGGTGAATCATTTCAAGAGTGAGAAGCGCCACCTT
CAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCCCCAGCCC
GACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCCACACTCC
GAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCCCGCCCCT
GTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAAGACCCTG
GTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGATGCCCCGT
GGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCCACTCTGC
GGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCGGACCCAC
CCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGTGGCAGGA
GCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACCAGGGCCT
CTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTTATAGATA
CTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGCCAGGGTG
AGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGTCAAGACA
CGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGCCCTCTAC
ACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTATGCTTCA
GGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCCCATGCGG
TGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCAGAGGTGC
AAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACCAAGTGCC
TGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCTGCTTCCC
AAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTGGTCAGCT
GCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCATCTAACTG
GAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCAAAACAGA
TCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATGGTGCCTT
GGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTATGTGGCA
ACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTAGACAATG
AGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCTAAAGCAT
ATTTTGATTTGCCATCAAGAGCAATAAAGCATTAAATCTTATTTTTAAAGGTGTTCTGCTTATCTGTCACTGAAAACTTGGTGAAATTTT

>52769_52769_7_MED29-MYO1D_MED29_chr19_39884277_ENST00000599213_MYO1D_chr17_31076024_ENST00000318217_length(amino acids)=637AA_BP=120
MAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDN
GQKSSDGPIQRFDKCLEEFYALCDQLELCLLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPE
GKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRY
KMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKRTKAALTIIR
YYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGL
QRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSV
SNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGF

--------------------------------------------------------------
>52769_52769_8_MED29-MYO1D_MED29_chr19_39884277_ENST00000599213_MYO1D_chr17_31076024_ENST00000394649_length(transcript)=4091nt_BP=387nt
GCACTTCCGGCGGTCTACGCGAGGAAGATGGCTGCATCCCAGCAGCAAGCTTCAGCGGCTTCCTCAGCTGCTGGTGTATCGGGTCCTAGT
TCGGCTGGCGGCCCGGGTCCCCAGCAGCAGCCGCAACCGCCAGCACAACTGGTGGGCCCTGCCCAGAGCGGCCTCCTGCAGCAACAGCAA
CAGGACTTCGATCCTGTGCAGCGTTATAAGATGCTCATCCCGCAGCTGAAGGAGAGTCTACAGACCTTGATGAAGGTTGCGGCCCAAAAC
TTGATTCAGAACACTAACATCGACAATGGACAAAAGAGCAGTGATGGACCCATACAGCGCTTTGACAAGTGCCTGGAAGAGTTCTATGCA
CTCTGTGACCAGCTGGAGCTGTGCCTGCTCTGTGCCTCAGACAAAATTCTGGAGTTTGATCGAGATTTTCGAATTCGACATTATGCAGGC
GATGTAGTCTATTCTGTCATTGGTTTTATTGACAAAAATAAAGATACTTTATTTCAAGATTTCAAGCGCCTTATGTATAACAGTTCAAAT
CCTGTGCTCAAGAATATGTGGCCTGAAGGCAAACTGAGCATTACAGAGGTGACCAAGCGACCTCTGACTGCTGCTACCTTGTTTAAGAAT
TCTATGATTGCTCTAGTAGACAACCTTGCATCAAAGGAACCATATTACGTTCGTTGCATCAAACCCAATGACAAGAAATCTCCACAGATA
TTTGATGATGAACGCTGCCGGCACCAAGTAGAATATCTTGGACTACTGGAAAATGTGAGAGTGCGTCGGGCAGGATTTGCCTTCCGCCAG
ACATACGAGAAGTTTCTTCACAGGTATAAGATGATCTCTGAATTCACCTGGCCCAACCATGACCTTCCTTCAGACAAAGAGGCTGTCAAG
AAACTAATTGAACGGTGTGGTTTTCAGGATGATGTAGCTTATGGGAAGACCAAAATTTTCATTCGAACACCCCGAACATTGTTTACCTTG
GAAGAACTCCGTGCCCAGATGCTCATAAGGATTGTCCTCTTTCTACAAAAGGTGTGGCGGGGCACCCTGGCCCGCATGCGGTACAAAAGA
ACCAAGGCAGCTCTGACAATAATCAGGTACTACCGGCGCTACAAAGTGAAGTCGTACATCCACGAGGTGGCCAGACGCTTCCATGGCGTC
AAGACCATGCGAGACTACGGGAAGCACGTGAAGTGGCCAAGCCCTCCTAAAGTTCTTCGCCGTTTTGAGGAGGCCCTGCAGACGATTTTC
AATAGATGGAGAGCATCCCAGCTCATCAAGAGCATTCCGGCCTCAGACCTGCCCCAGGTCAGGGCAAAGGTTGCAGCCGTGGAAATGTTG
AAGGGTCAAAGGGCTGACCTCGGGCTCCAGAGGGCCTGGGAGGGCAACTATCTTGCTTCAAAGCCAGATACACCTCAGACCTCAGGCACT
TTTGTCCCTGTTGCTAATGAATTGAAACGGAAGGACAAATACATGAATGTCCTCTTTTCCTGTCACGTCCGTAAGGTAAATCGATTTAGT
AAGGTGGAAGACAGAGCAATTTTTGTCACTGACCGTCACCTGTATAAAATGGATCCCACTAAACAGTACAAGGTGATGAAGACTATCCCT
CTATACAATTTGACTGGTCTGAGTGTCTCCAATGGAAAGGACCAACTTGTAGTGTTCCATACGAAAGACAACAAAGACCTCATTGTCTGC
CTCTTCAGCAAACAGCCAACCCATGAGAGTCGAATTGGAGAACTTGTTGGAGTGCTGGTGAATCATTTCAAGAGTGAGAAGCGCCACCTT
CAAGTGAACGTCACCAACCCAGTACAGTGCAGCCTGCACGGGAAGAAGTGCACCGTCTCCGTGGAGACGCGGCTCAACCAGCCCCAGCCC
GACTTCACCAAGAATCGCTCGGGCTTCATCCTCAGCGTGCCCGGGAACTGACGCCCCGCGGAGGCCTGGCCCGGAGCCCGGCCACACTCC
GAGTCCTGGGTCCCAGTCCAGCTGCTGCCTCCCAACCCATGCCCGCTAGAAACCTGCTGCGAGGGCCCCTCCCAGAGGAGCCCCGCCCCT
GTAAGATTTCCTTCCTGGTTTTCTGCCTTTGGTATCATCTTCCTCTGTCCTTACTGTCCACGGTCCCTGTTCAATAAGCCAAAGACCCTG
GTGCCCCGCCCAGACCCCTGGGCTGACGTCCAGACCAATCTCACCCCAGAGGCAACTGGATGGTGCCTTTAGTTGGTGCGGATGCCCCGT
GGCCAGGTCAAGTCAGAGCACCTGGACAGGTGTCCTCCCTGCTGCTGACCCTGCAGAGGGAAGGGGTGGGGATGCAGGACCCCACTCTGC
GGGAGCCCCATAGCCACCTCTCTTGCCCAAGGTGAGCCAGCCCTGGGGACCCAGCTCAGGGAGGCTCTGCTCAGAGTTCGGCGGACCCAC
CCCAACCCAACTCCCAGCCGCCAGCCAAAGCCACTGGGTGAGCAGAGTCACCCACAGGGCCAGCCCCTCAGCCAGGAGCCAGTGGCAGGA
GCGGAACAGCCCATCCAGCAGAGTGAGTCCATCCTTCCCAGGTTCTCCCCTGGGAGACTCCCTTTGCCACCAAGGCCCCCACCAGGGCCT
CTGACCACCGCTCTGGAGAGGACAGTGTGGCATGCTCCAAGGATCATCTTACTTAACTCGCAGCCTGTGGCTGTGGTCCTCTTATAGATA
CTTTCACCGTTTGCAGGGTTGCTAATCAGATACCTGCTGTCACCACACTTGGGTCAGGAACCCTAATGAGAACGGGGAGCTGCCAGGGTG
AGGGCAGCCCTCAGGGTCGGCCGCTTTCCCTCTGGACCACCTCCCGCTGCGTTTCCTACTCAGAGAAACAGCAAGGGCGGGGTCAAGACA
CGGGATGACGGGAAGCAGGAAGCGGGGCAGCAGCACAGCGTGGGGTCCTGGCACTGCAGGCCAGGCCAGGATGCCCACCCCGCCCTCTAC
ACGGCCCCTTGGGGCCTGCGCCCGTGAAACTGGTGCCAGGGAGCACTGCCAGCTTGCCAGTTTCTGCCCAGCAAAAGCACGTATGCTTCA
GGGGCCTTCTGAGACCACCTTCCCCACTGAGCCCCAGCTGCTGAGAAGGCCTTGAGGGAAGTAGAGGCTGGGAGCAAATGCCCCATGCGG
TGAGAGGATGAGGGGAGCCTACGCCTCAGGCATGTGGTGAGAGGATGAGGGGGAGGGAGCCAACGCCTCAGGTGGAGTGGGCAGAGGTGC
AAGAGAGGGATGTACTGAAGCTTCTTCCCGTCCTGCCACAGACACTTCTCCTGCCTTCCCACCCTGACCCGGCAGAACCCACCAAGTGCC
TGTGTGCAGCCTCCTGTGCCTCACCCAGGGCCTGACCCCAGAGTGGTCCCAACAACCCGGTCTCATGCCCACTCCCCATCCCTGCTTCCC
AAAAATTGCACTGTGTGCAGTTTGCAACAAAGAATCCCGCTGGCATCCTGTCCTTGGGAACCCTTTCTCATTCTCCAAGCCTGGTCAGCT
GCCTGCACAGGCAGAGGTGCCCTCAGCCCAGATTAGCAACACTCATAGTTTTGCCAATTACCAGTAGACACTAGTGGAACCATCTAACTG
GAACTTCCTCTCTCCTTCCACTTATTTCCTCAAACTTGTTGCTTTACACTAGACACATGCAAATGTATGTTTTAAACACACCAAAACAGA
TCATGCCAAATGAGTTGCCTGTCAAAGGCTGGAGGGCAGGAGGAGGGCCTGGGTTTGGGTTCTTTCCTCCCAGCCTTTGGATGGTGCCTT
GGGCCCCTTAGCCCCAGCGCCAGGGCCTCCCAGCTGAGGCCACAGGACAAGCACTTTTTTATGATGTACTAAAAGCCACAGTATGTGGCA
ACTGCAAAAGGATCAGGAATTTAGGGTATGATCTCGGTCACGTGTCCCGGGCGCTGAGGGGAAAGGAAGCGGGCATGATTGTAGACAATG
AGGGGGTTCTCTTGATGTAATGAAATGCAATTTTATGGTTTGGTGCAAAAACTCCTATTTTCCAGTAAATTAACTTTATTTCTAAAGCAT

>52769_52769_8_MED29-MYO1D_MED29_chr19_39884277_ENST00000599213_MYO1D_chr17_31076024_ENST00000394649_length(amino acids)=637AA_BP=120
MAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDN
GQKSSDGPIQRFDKCLEEFYALCDQLELCLLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPE
GKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRY
KMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKRTKAALTIIR
YYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGL
QRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSV
SNGKDQLVVFHTKDNKDLIVCLFSKQPTHESRIGELVGVLVNHFKSEKRHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGF

--------------------------------------------------------------
>52769_52769_9_MED29-MYO1D_MED29_chr19_39884277_ENST00000599213_MYO1D_chr17_31076024_ENST00000579584_length(transcript)=2148nt_BP=387nt
GCACTTCCGGCGGTCTACGCGAGGAAGATGGCTGCATCCCAGCAGCAAGCTTCAGCGGCTTCCTCAGCTGCTGGTGTATCGGGTCCTAGT
TCGGCTGGCGGCCCGGGTCCCCAGCAGCAGCCGCAACCGCCAGCACAACTGGTGGGCCCTGCCCAGAGCGGCCTCCTGCAGCAACAGCAA
CAGGACTTCGATCCTGTGCAGCGTTATAAGATGCTCATCCCGCAGCTGAAGGAGAGTCTACAGACCTTGATGAAGGTTGCGGCCCAAAAC
TTGATTCAGAACACTAACATCGACAATGGACAAAAGAGCAGTGATGGACCCATACAGCGCTTTGACAAGTGCCTGGAAGAGTTCTATGCA
CTCTGTGACCAGCTGGAGCTGTGCCTGCTCTGTGCCTCAGACAAAATTCTGGAGTTTGATCGAGATTTTCGAATTCGACATTATGCAGGC
GATGTAGTCTATTCTGTCATTGGTTTTATTGACAAAAATAAAGATACTTTATTTCAAGATTTCAAGCGCCTTATGTATAACAGTTCAAAT
CCTGTGCTCAAGAATATGTGGCCTGAAGGCAAACTGAGCATTACAGAGGTGACCAAGCGACCTCTGACTGCTGCTACCTTGTTTAAGAAT
TCTATGATTGCTCTAGTAGACAACCTTGCATCAAAGGAACCATATTACGTTCGTTGCATCAAACCCAATGACAAGAAATCTCCACAGATA
TTTGATGATGAACGCTGCCGGCACCAAGTAGAATATCTTGGACTACTGGAAAATGTGAGAGTGCGTCGGGCAGGATTTGCCTTCCGCCAG
ACATACGAGAAGTTTCTTCACAGGTATAAGATGATCTCTGAATTCACCTGGCCCAACCATGACCTTCCTTCAGACAAAGAGGCTGTCAAG
AAACTAATTGAACGGTGTGGTTTTCAGGATGATGTAGCTTATGGGAAGACCAAAATTTTCATTCGAACACCCCGAACATTGTTTACCTTG
GAAGAACTCCGTGCCCAGATGCTCATAAGGATTGTCCTCTTTCTACAAAAGGTGTGGCGGGGCACCCTGGCCCGCATGCGGTACAAAAGA
ACCAAGGCAGCTCTGACAATAATCAGGTACTACCGGCGCTACAAAGTGAAGTCGTACATCCACGAGGTGGCCAGACGCTTCCATGGCGTC
AAGACCATGCGAGACTACGGGAAGCACGTGAAGTGGCCAAGCCCTCCTAAAGTTCTTCGCCGTTTTGAGGAGGCCCTGCAGACGATTTTC
AATAGATGGAGAGCATCCCAGCTCATCAAGAGCATTCCGGCCTCAGACCTGCCCCAGGTCAGGGCAAAGGTTGCAGCCGTGGAAATGTTG
AAGGGTCAAAGGGCTGACCTCGGGCTCCAGAGGGCCTGGGAGGGCAACTATCTTGCTTCAAAGCCAGATACACCTCAGACCTCAGGCACT
TTTGTCCCTGTTGCTAATGAATTGAAACGGAAGGACAAATACATGAATGTCCTCTTTTCCTGTCACGTCCGTAAGGTAAATCGATTTAGT
AAGGTGGAAGACAGAGCAATTTTTGTCACTGACCGTCACCTGTATAAAATGGATCCCACTAAACAGTACAAGGTGATGAAGACTATCCCT
CTATACAATTTGACTGGTCTGAGTGTCTCCAATGGAAAGGACCAACTTGTAGTGTTCCATACGAAAGACAACAAAGACCTCATTGTCTGC
CTCTTCAGCAAACAGCCAACCCATGAGAGTCGAATTGGAGAACTTGTTGGAGTGCTGGTGAATCATTTCAAGAGAAACCATCTGCTTATA
CTCTGAATAAAATTCAAGAAAGCATAGATTCTACATAAACAGGCCCAAGATTACATGGCAAACTGAGATGAAGAGGATGCTGGCTGAGAA
ACAAACAAAAGTGTTCAATTATTTGAATGAAGTAAGGAAAGATATTTTAAAATGTAAATCAACATTAAAATCTGAAAATGGCACAGTTGA
TATTGCAGAAAATAGAATTGATGTGAAAGGAAAGTTTGAAGTCTCTCAGTGTGCAGAATTTACTGTTATAATGGGCAACATGTTAACTTT

>52769_52769_9_MED29-MYO1D_MED29_chr19_39884277_ENST00000599213_MYO1D_chr17_31076024_ENST00000579584_length(amino acids)=592AA_BP=120
MAASQQQASAASSAAGVSGPSSAGGPGPQQQPQPPAQLVGPAQSGLLQQQQQDFDPVQRYKMLIPQLKESLQTLMKVAAQNLIQNTNIDN
GQKSSDGPIQRFDKCLEEFYALCDQLELCLLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPE
GKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRY
KMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKRTKAALTIIR
YYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGL
QRAWEGNYLASKPDTPQTSGTFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTKQYKVMKTIPLYNLTGLSV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MED29-MYO1D


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MED29-MYO1D


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MED29-MYO1D


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource