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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:MET-CAPZA2 (FusionGDB2 ID:53019) |
Fusion Gene Summary for MET-CAPZA2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MET-CAPZA2 | Fusion gene ID: 53019 | Hgene | Tgene | Gene symbol | MET | CAPZA2 | Gene ID | 8731 | 830 |
| Gene name | RNA guanine-7 methyltransferase | capping actin protein of muscle Z-line subunit alpha 2 | |
| Synonyms | CMT1|CMT1c|MET|Met|RG7MT1|cm1p|hCMT1|hMet | CAPPA2|CAPZ | |
| Cytomap | 18p11.21 | 7q31.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mRNA cap guanine-N7 methyltransferaseRNA (guanine-7-) methyltransferasehcm1pmRNA (guanine-7-)methyltransferasemRNA (guanine-N(7)-)-methyltransferasemRNA cap methyltransferase | F-actin-capping protein subunit alpha-2F-actin capping protein alpha-2 subunitcapZ alpha-2capping actin protein of muscle Z-line alpha subunit 2capping protein (actin filament) muscle Z-line, alpha 2epididymis secretory sperm binding protein | |
| Modification date | 20200329 | 20200313 | |
| UniProtAcc | . | P47755 | |
| Ensembl transtripts involved in fusion gene | ENST00000318493, ENST00000397752, ENST00000436117, ENST00000495962, ENST00000539704, | ENST00000466023, ENST00000361183, ENST00000458284, ENST00000490693, | |
| Fusion gene scores | * DoF score | 11 X 10 X 9=990 | 8 X 5 X 7=280 |
| # samples | 16 | 8 | |
| ** MAII score | log2(16/990*10)=-2.62935662007961 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/280*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MET [Title/Abstract] AND CAPZA2 [Title/Abstract] AND fusion [Title/Abstract] Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer (pmid: 28512244) | ||
| Most frequent breakpoint | CAPZA2(116550365)-MET(116409699), # samples:2 CAPZA2(116528244)-MET(116395409), # samples:2 CAPZA2(116528244)-MET(116414935), # samples:2 MET(116399544)-CAPZA2(116528181), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | CAPZA2-MET seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. CAPZA2-MET seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. CAPZA2-MET seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. CAPZA2-MET seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MET | GO:0006370 | 7-methylguanosine mRNA capping | 27422871 |
| Fusion gene breakpoints across MET (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across CAPZA2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | UCEC | TCGA-BK-A139-01A | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| ChimerDB4 | UCEC | TCGA-BK-A139-02A | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
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Fusion Gene ORF analysis for MET-CAPZA2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000318493 | ENST00000466023 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| 5CDS-intron | ENST00000397752 | ENST00000466023 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| In-frame | ENST00000318493 | ENST00000361183 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| In-frame | ENST00000318493 | ENST00000458284 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| In-frame | ENST00000318493 | ENST00000490693 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| In-frame | ENST00000397752 | ENST00000361183 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| In-frame | ENST00000397752 | ENST00000458284 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| In-frame | ENST00000397752 | ENST00000490693 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-3CDS | ENST00000436117 | ENST00000361183 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-3CDS | ENST00000436117 | ENST00000458284 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-3CDS | ENST00000436117 | ENST00000490693 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-3CDS | ENST00000495962 | ENST00000361183 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-3CDS | ENST00000495962 | ENST00000458284 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-3CDS | ENST00000495962 | ENST00000490693 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-3CDS | ENST00000539704 | ENST00000361183 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-3CDS | ENST00000539704 | ENST00000458284 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-3CDS | ENST00000539704 | ENST00000490693 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-intron | ENST00000436117 | ENST00000466023 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-intron | ENST00000495962 | ENST00000466023 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| intron-intron | ENST00000539704 | ENST00000466023 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000397752 | MET | chr7 | 116399544 | + | ENST00000361183 | CAPZA2 | chr7 | 116528181 | + | 7568 | 2564 | 200 | 3385 | 1061 |
| ENST00000397752 | MET | chr7 | 116399544 | + | ENST00000458284 | CAPZA2 | chr7 | 116528181 | + | 3895 | 2564 | 200 | 3043 | 947 |
| ENST00000397752 | MET | chr7 | 116399544 | + | ENST00000490693 | CAPZA2 | chr7 | 116528181 | + | 3322 | 2564 | 200 | 2965 | 921 |
| ENST00000318493 | MET | chr7 | 116399544 | + | ENST00000361183 | CAPZA2 | chr7 | 116528181 | + | 7609 | 2605 | 187 | 3426 | 1079 |
| ENST00000318493 | MET | chr7 | 116399544 | + | ENST00000458284 | CAPZA2 | chr7 | 116528181 | + | 3936 | 2605 | 187 | 3084 | 965 |
| ENST00000318493 | MET | chr7 | 116399544 | + | ENST00000490693 | CAPZA2 | chr7 | 116528181 | + | 3363 | 2605 | 187 | 3006 | 939 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000397752 | ENST00000361183 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + | 8.52E-05 | 0.99991477 |
| ENST00000397752 | ENST00000458284 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + | 0.000121268 | 0.99987876 |
| ENST00000397752 | ENST00000490693 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + | 0.000137402 | 0.99986255 |
| ENST00000318493 | ENST00000361183 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + | 0.000217308 | 0.99978274 |
| ENST00000318493 | ENST00000458284 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + | 0.000106795 | 0.9998932 |
| ENST00000318493 | ENST00000490693 | MET | chr7 | 116399544 | + | CAPZA2 | chr7 | 116528181 | + | 0.000113002 | 0.999887 |
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Fusion Genomic Features for MET-CAPZA2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for MET-CAPZA2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:116550365/chr7:116409699) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | CAPZA2 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000318493 | + | 10 | 21 | 27_515 | 806 | 1409.0 | Domain | Sema |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000318493 | + | 10 | 21 | 563_655 | 806 | 1409.0 | Domain | Note=IPT/TIG 1 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000318493 | + | 10 | 21 | 657_739 | 806 | 1409.0 | Domain | Note=IPT/TIG 2 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000397752 | + | 10 | 21 | 27_515 | 788 | 1391.0 | Domain | Sema |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000397752 | + | 10 | 21 | 563_655 | 788 | 1391.0 | Domain | Note=IPT/TIG 1 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000397752 | + | 10 | 21 | 657_739 | 788 | 1391.0 | Domain | Note=IPT/TIG 2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000318493 | + | 10 | 21 | 1078_1345 | 806 | 1409.0 | Domain | Protein kinase |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000318493 | + | 10 | 21 | 742_836 | 806 | 1409.0 | Domain | Note=IPT/TIG 3 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000397752 | + | 10 | 21 | 1078_1345 | 788 | 1391.0 | Domain | Protein kinase |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000397752 | + | 10 | 21 | 742_836 | 788 | 1391.0 | Domain | Note=IPT/TIG 3 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000436117 | + | 1 | 9 | 1078_1345 | 0 | 765.0 | Domain | Protein kinase |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000436117 | + | 1 | 9 | 27_515 | 0 | 765.0 | Domain | Sema |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000436117 | + | 1 | 9 | 563_655 | 0 | 765.0 | Domain | Note=IPT/TIG 1 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000436117 | + | 1 | 9 | 657_739 | 0 | 765.0 | Domain | Note=IPT/TIG 2 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000436117 | + | 1 | 9 | 742_836 | 0 | 765.0 | Domain | Note=IPT/TIG 3 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000318493 | + | 10 | 21 | 1084_1092 | 806 | 1409.0 | Nucleotide binding | ATP |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000397752 | + | 10 | 21 | 1084_1092 | 788 | 1391.0 | Nucleotide binding | ATP |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000436117 | + | 1 | 9 | 1084_1092 | 0 | 765.0 | Nucleotide binding | ATP |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000318493 | + | 10 | 21 | 25_932 | 806 | 1409.0 | Topological domain | Extracellular |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000318493 | + | 10 | 21 | 956_1390 | 806 | 1409.0 | Topological domain | Cytoplasmic |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000397752 | + | 10 | 21 | 25_932 | 788 | 1391.0 | Topological domain | Extracellular |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000397752 | + | 10 | 21 | 956_1390 | 788 | 1391.0 | Topological domain | Cytoplasmic |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000436117 | + | 1 | 9 | 25_932 | 0 | 765.0 | Topological domain | Extracellular |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000436117 | + | 1 | 9 | 956_1390 | 0 | 765.0 | Topological domain | Cytoplasmic |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000318493 | + | 10 | 21 | 933_955 | 806 | 1409.0 | Transmembrane | Helical |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000397752 | + | 10 | 21 | 933_955 | 788 | 1391.0 | Transmembrane | Helical |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000436117 | + | 1 | 9 | 933_955 | 0 | 765.0 | Transmembrane | Helical |
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Fusion Gene Sequence for MET-CAPZA2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >53019_53019_1_MET-CAPZA2_MET_chr7_116399544_ENST00000318493_CAPZA2_chr7_116528181_ENST00000361183_length(transcript)=7609nt_BP=2605nt GCCCTCGCCGCCCGCGGCGCCCCGAGCGCTTTGTGAGCAGATGCGGAGCCGAGTGGAGGGCGCGAGCCAGATGCGGGGCGACAGCTGACT TGCTGAGAGGAGGCGGGGAGGCGCGGAGCGCGCGTGTGGTCCTTGCGCCGCTGACTTCTCCACTGGTTCCTGGGCACCGAAAGATAAACC TCTCATAATGAAGGCCCCCGCTGTGCTTGCACCTGGCATCCTCGTGCTCCTGTTTACCTTGGTGCAGAGGAGCAATGGGGAGTGTAAAGA GGCACTAGCAAAGTCCGAGATGAATGTGAATATGAAGTATCAGCTTCCCAACTTCACCGCGGAAACACCCATCCAGAATGTCATTCTACA TGAGCATCACATTTTCCTTGGTGCCACTAACTACATTTATGTTTTAAATGAGGAAGACCTTCAGAAGGTTGCTGAGTACAAGACTGGGCC TGTGCTGGAACACCCAGATTGTTTCCCATGTCAGGACTGCAGCAGCAAAGCCAATTTATCAGGAGGTGTTTGGAAAGATAACATCAACAT GGCTCTAGTTGTCGACACCTACTATGATGATCAACTCATTAGCTGTGGCAGCGTCAACAGAGGGACCTGCCAGCGACATGTCTTTCCCCA CAATCATACTGCTGACATACAGTCGGAGGTTCACTGCATATTCTCCCCACAGATAGAAGAGCCCAGCCAGTGTCCTGACTGTGTGGTGAG CGCCCTGGGAGCCAAAGTCCTTTCATCTGTAAAGGACCGGTTCATCAACTTCTTTGTAGGCAATACCATAAATTCTTCTTATTTCCCAGA TCATCCATTGCATTCGATATCAGTGAGAAGGCTAAAGGAAACGAAAGATGGTTTTATGTTTTTGACGGACCAGTCCTACATTGATGTTTT ACCTGAGTTCAGAGATTCTTACCCCATTAAGTATGTCCATGCCTTTGAAAGCAACAATTTTATTTACTTCTTGACGGTCCAAAGGGAAAC TCTAGATGCTCAGACTTTTCACACAAGAATAATCAGGTTCTGTTCCATAAACTCTGGATTGCATTCCTACATGGAAATGCCTCTGGAGTG TATTCTCACAGAAAAGAGAAAAAAGAGATCCACAAAGAAGGAAGTGTTTAATATACTTCAGGCTGCGTATGTCAGCAAGCCTGGGGCCCA GCTTGCTAGACAAATAGGAGCCAGCCTGAATGATGACATTCTTTTCGGGGTGTTCGCACAAAGCAAGCCAGATTCTGCCGAACCAATGGA TCGATCTGCCATGTGTGCATTCCCTATCAAATATGTCAACGACTTCTTCAACAAGATCGTCAACAAAAACAATGTGAGATGTCTCCAGCA TTTTTACGGACCCAATCATGAGCACTGCTTTAATAGGACACTTCTGAGAAATTCATCAGGCTGTGAAGCGCGCCGTGATGAATATCGAAC AGAGTTTACCACAGCTTTGCAGCGCGTTGACTTATTCATGGGTCAATTCAGCGAAGTCCTCTTAACATCTATATCCACCTTCATTAAAGG AGACCTCACCATAGCTAATCTTGGGACATCAGAGGGTCGCTTCATGCAGGTTGTGGTTTCTCGATCAGGACCATCAACCCCTCATGTGAA TTTTCTCCTGGACTCCCATCCAGTGTCTCCAGAAGTGATTGTGGAGCATACATTAAACCAAAATGGCTACACACTGGTTATCACTGGGAA GAAGATCACGAAGATCCCATTGAATGGCTTGGGCTGCAGACATTTCCAGTCCTGCAGTCAATGCCTCTCTGCCCCACCCTTTGTTCAGTG TGGCTGGTGCCACGACAAATGTGTGCGATCGGAGGAATGCCTGAGCGGGACATGGACTCAACAGATCTGTCTGCCTGCAATCTACAAGGT TTTCCCAAATAGTGCACCCCTTGAAGGAGGGACAAGGCTGACCATATGTGGCTGGGACTTTGGATTTCGGAGGAATAATAAATTTGATTT AAAGAAAACTAGAGTTCTCCTTGGAAATGAGAGCTGCACCTTGACTTTAAGTGAGAGCACGATGAATACATTGAAATGCACAGTTGGTCC TGCCATGAATAAGCATTTCAATATGTCCATAATTATTTCAAATGGCCACGGGACAACACAATACAGTACATTCTCCTATGTGGATCCTGT AATAACAAGTATTTCGCCGAAATACGGTCCTATGGCTGGTGGCACTTTACTTACTTTAACTGGAAATTACCTAAACAGTGGGAATTCTAG ACACATTTCAATTGGTGGAAAAACATGTACTTTAAAAAGTGTGTCAAACAGTATTCTTGAATGTTATACCCCAGCCCAAACCATTTCAAC TGAGTTTGCTGTTAAATTGAAAATTGACTTAGCCAACCGAGAGACAAGCATCTTCAGTTACCGTGAAGATCCCATTGTCTATGAAATTCA TCCAACCAAATCTTTTATTAGTACTTGGTGGAAAGAACCTCTCAACATTGTCAGTTTTCTATTTTGCTTTGCCAGTGGTGGGAGCACAAT AACAGGTGTTGGGAAAAACCTGAATTCAGTTAGTGTCCCGAGAATGGTCATAAATGTGCATGAAGCAGGAAGGAACTTTACAGTGGTGCG TATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAATTTAATGAGGTTTTCAATGATGTTCGGTTACTGCTTAATAATGACAATCT TCTCAGGGAAGGAGCAGCCCATGCATTTGCACAGTATAACTTGGACCAGTTTACTCCAGTAAAAATTGAAGGTTATGAAGATCAGGTATT GATAACAGAACATGGCGACTTGGGAAATGGAAAGTTTTTGGATCCAAAGAACAGAATCTGTTTTAAATTTGATCACTTAAGGAAGGAGGC AACTGATCCAAGACCCTGTGAAGTAGAAAATGCAGTTGAATCATGGAGAACTTCAGTAGAAACTGCTCTGAGAGCTTACGTAAAAGAACA TTACCCGAATGGAGTCTGCACTGTGTATGGCAAAAAAATAGATGGACAGCAAACCATTATTGCATGCATAGAAAGCCATCAGTTCCAAGC AAAAAATTTTTGGAATGGTCGTTGGAGGTCAGAATGGAAGTTTACAATCACTCCTTCAACCACTCAAGTGGTTGGCATCTTGAAAATTCA GGTTCATTATTATGAAGATGGTAATGTTCAGCTAGTGAGTCATAAAGATATACAAGATTCCCTAACAGTGTCTAATGAAGTGCAAACAGC AAAAGAATTTATAAAGATTGTAGAAGCTGCAGAAAATGAATACCAGACTGCCATCAGTGAGAATTATCAGACAATGTCGGACACTACTTT CAAAGCCTTACGTCGACAGTTGCCAGTTACACGCACTAAGATTGATTGGAACAAGATCCTTAGCTACAAGATTGGCAAAGAGATGCAGAA TGCATAAGATGAACATTGCATGACCGGATCATTTTAGTGTCTTTGCGTTAAAAAATCATTGCAAAAGTATTCTGAACTGTCAAGCTGCCC AGTCAGATGGGCTGTTGCCATTTAAAATCACTGTAATTAATTAGTTTGATTAGAGCACAAAGCTTAGCTAATCAACCATTATTTTTCATT TTGTTTGTTCTAAGAGGATTGAAAATCAGTTTAGTTTAAATGTCTTTCTGTTAGGCCTTTCTTTCTTACAATGAAGAGATGATTCTTCTA GTTTATGGTTAAAAGTTTTTGAAGTGTCTCAAAAATATTTTACTAACTGTAACCCTAAAATTGATGTCTTTTGGTTTATGAAATCAGTAA TTTTTGATATTTCCCCAGTTCTTTTTAATGGGGTCAATAATGGACATTCTAGTTTAAGGTGGTTGATGGATTTAGCCATATATGCTGCTA AAGAAATTGTCTACCTTTTCTTCCTCACCTGTTCCATTTATGTAAAGTTGAGATTAGAGGGAAAGCATTTTCTATATCAATTGTGTTTAA ACCTTTCAAGAAGGTTATTTAGCTAGCTTAGTGTTGAACTAAATTTTTTTTAAACAAGGCAAGGTCTAATGCTGTTTTGAGATTCTGAAA TTAATGAAAATACTTATTTCAGAAATGCATTTAATGCTTTTTTTCTTGTGACAGTTACGCAAATCAGCTTGAATTCCATATGTCCCTGAG TTATTTTTATCATAAAGCCACAAATGTATTATAACAAGGCAAATTGTAATATATATAATCCTGAACTCATGACCATGTCTCGGTTTATTT TTTTTTTCTTGGATTGAAAAGTACTGAAATTCAATGTGACATTAAAATGCAAATTTTCCTATTTATTTGAGTAGAAAATCACTTACCAGT GAGCATATATATTTTAAAATACTTTCTTTGGATATTGTAATTCTTAACTGGTTGTAAATTAGAAAAGCTGGGATTACATATGGTGTGCGG TTACAGTCTAAATTTTTTCATCCTCCTATGCATCATAAGCATGTTTGTAATATTTTCAAAAATAGTTCTACTGATGCTACAGGAATTTCA AGCCTGTGGTGAATGTTAGTATTTACCATAGGGAGTGAAGTGGAGTTATGGTTTCATTCAATAGAGTATTGCTGATTATACTTGAGTGGA ATCCTTTCCTCACGTACTCCCACAGACGTCTGGGCCTGGAAATTTTTTTTTTATTTTATTTTATTGTTTTTTTTTTTAGAAAAACACCAC TTTTATTATGTACAATAAAATATTTCATTAGCTTGAATTGTATAGATTTTTAAAAATTCAATGAAAGCATGTTGTTTAATTTCTTTTTAA AATCACTGTTGGGCTTTGAAAGCATTGAGAATATAATATGAAATTATGACATTTTGTCTAAATCATCTTTTCTTTAGTTTTAAAATACAA GTTTTGGCACATTGGGATTCCTAAAGAAAATGAATTGGTAACATTAATTATCTGTTCCTTTTTAAAATATATATATTTGAAAGTTTGATG ATGGTGAACTAAATACTAGATCTAATTGACAAGCTTAGTTGTATCAGTTAGGCCATCATGAGTTTCTATCCCATGAAAGTCATCAATTTC CTATCTCTGTTCTAGTCTGGAATGCATTACTGAAAATGTATGCAACTGTTTTTAAGGTGATTTGCTTGTGAGACGGAAGATTTATCAAAA ATAATTTAGAACAGGCTGGGCGCGGTGGCTCACATCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACGGGGTCAGGAGAT TGAGACCACCCTGACTAACACAGTGAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCCGGGTGTGGTGACAGGCGCTTGTAGTCCCA GCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTCGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTG GGTGACAGAGCAAGACTCTGTCTCAAAAAATAATAATAATAATAATAATAATATAATTTAGAACAGTCTGAAATAATGATGGCACAGAAT AGTCTTTTATAGTATAAGAATGGCATTTATTAGGCAGGGCACAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTG GATCACGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGCTGAAACCCCGTCTCTACTAAAAACAAAAAAAAATTAGCCGGGGATGGT GATGCGCGCCTGTAATCCCAACTACTCAGGAGGCTGAGACAGGAGAATCATTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCAGAGATCG AGCCACTGTACTCCAGCCTGGGTGACACAGGGAGCCTCTGTCTCAAAATAATAATAATAATAAAAGAATGGCATTTATTAAAGTGAAAGA AGAATGGAAACCCAGAGTATCCTATAGCTCAGGGATGTAATTTTAGTAGGAGACATTATGGCTGCTTTGCTGAGTAGGCTGAAGTGTGGT GGCAAAGGCATAATCAGGGAGAACAGCTAGGAGACTACTGCAGTAATCTAGTTGAGAGAGCATGCTGGCTTGGACTGAGGTGGTTGCTGT AGAGGTGGTATAAAGCAGTGAGGTCTAGGTATATCCTAAAGGTAAAATCAGCAAGACCTGGGGAGAGTTTGGTCATGGAGTGTGAGATAA AGAGAACCATGTCTGGGGCTGGAGAAATTGAGGAAGATTCTTGTAGGAGCAAGTTGGTTTGGAGAAGAAGGCTGGTCAGGAGCTCAGTTT TCTATTCAAAGGAGAAATATCTCATGTAGCAGTTAGATACAGGAGACAGGAACTAGAGGAAAGCTCTGGGCTAGAAGAATGGGAAAGTGC ATGAACCTGGAAACAATTTTATAGGCAGACAGGATGAAGGACCTCAAGGTTAGTGATAATGAATTTAAAGTAAATGAGACCAATGATGAG CATGGCTGTATGTTTTTCTTCAACCGTGTAAAGCTGTTTGGGTGCAGGCATAGAGTAGATGAAATAAATTTCACCAGGGCTGTGGTTTTG CCCAGAGTGAATGACCACATGAAGAGGGGCAGGGTATGATGATGGTCTGTGGAATTTCAGCTGGGTAAGCAGGGAAGTGAGGGCTTGAGA CGGGGGGAGGGATAGTGAAAATGTACAACCAGTGGATTATAGGTGTGTTAAAGTAGGGGAACTAGAAAGAATGACCTGGAAATGTAAGAA GTGGGCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTAGGAGGCTGAGGTGGGTGGATCATGAGGTCCAGAGATCAAGACCATC CTGGCCAATATGGTGCAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGTGTGCCTGTAGTCCCAGCTACTAGGGAGG CTGAGGCAGGAGAATCGCTTGAACCCAGGATGCGAAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGGCTGGCGACAGAGCGAG ACTCTGTCCCAAAAAAAAAAAAAAGTGGTGGGCTGGCCACGATGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCCACGGCAAGTGGA TCATTTAAGGTCAGGAGTTCAAGACCAGTCTGGCTAATATGATGAAACCCCTTCTGTATTAAAAATACAAATATTAGCCGGGCATGGTGG CACATGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCTTTGAACCCAGGAAGTGACAGTTACAACGAGCGGAGACTGTGC CACTTCACTGCAGCCTGGGTGACAGGGTGAGAGTCTGTCTCAAAAAAAGAAAAAGGAAATGTAAGAAGTGGTGATTGGAGAATGGTGTGC TTAATTAAAATTGAGGTTTTGAGGAGTTACTAGTAATGACAAATATGACCAACGGAGTGACTGGCTGAGGGGAGAGAGGAGAGGACTTAA GCAACTGTGCCACTCAGCATTGGAAAGGTCACCTCTGTGACATTAAAATCAAGAATTCTGATAGAAGTAAGAGTTCTGGCATGAGTGGTG CTTTTCCAGAGTACACTTGGATATATGATTACATTTTAATAAGTTATATAAATATGCAGATATTCATGCGGCTTTTCCTCATTTGGGATT >53019_53019_1_MET-CAPZA2_MET_chr7_116399544_ENST00000318493_CAPZA2_chr7_116528181_ENST00000361183_length(amino acids)=1079AA_BP=0 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVL EHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLD AQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDL TIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAM NKHFNMSIIISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVVRIA AKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATD PRPCEVENAVESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVH -------------------------------------------------------------- >53019_53019_2_MET-CAPZA2_MET_chr7_116399544_ENST00000318493_CAPZA2_chr7_116528181_ENST00000458284_length(transcript)=3936nt_BP=2605nt GCCCTCGCCGCCCGCGGCGCCCCGAGCGCTTTGTGAGCAGATGCGGAGCCGAGTGGAGGGCGCGAGCCAGATGCGGGGCGACAGCTGACT TGCTGAGAGGAGGCGGGGAGGCGCGGAGCGCGCGTGTGGTCCTTGCGCCGCTGACTTCTCCACTGGTTCCTGGGCACCGAAAGATAAACC TCTCATAATGAAGGCCCCCGCTGTGCTTGCACCTGGCATCCTCGTGCTCCTGTTTACCTTGGTGCAGAGGAGCAATGGGGAGTGTAAAGA GGCACTAGCAAAGTCCGAGATGAATGTGAATATGAAGTATCAGCTTCCCAACTTCACCGCGGAAACACCCATCCAGAATGTCATTCTACA TGAGCATCACATTTTCCTTGGTGCCACTAACTACATTTATGTTTTAAATGAGGAAGACCTTCAGAAGGTTGCTGAGTACAAGACTGGGCC TGTGCTGGAACACCCAGATTGTTTCCCATGTCAGGACTGCAGCAGCAAAGCCAATTTATCAGGAGGTGTTTGGAAAGATAACATCAACAT GGCTCTAGTTGTCGACACCTACTATGATGATCAACTCATTAGCTGTGGCAGCGTCAACAGAGGGACCTGCCAGCGACATGTCTTTCCCCA CAATCATACTGCTGACATACAGTCGGAGGTTCACTGCATATTCTCCCCACAGATAGAAGAGCCCAGCCAGTGTCCTGACTGTGTGGTGAG CGCCCTGGGAGCCAAAGTCCTTTCATCTGTAAAGGACCGGTTCATCAACTTCTTTGTAGGCAATACCATAAATTCTTCTTATTTCCCAGA TCATCCATTGCATTCGATATCAGTGAGAAGGCTAAAGGAAACGAAAGATGGTTTTATGTTTTTGACGGACCAGTCCTACATTGATGTTTT ACCTGAGTTCAGAGATTCTTACCCCATTAAGTATGTCCATGCCTTTGAAAGCAACAATTTTATTTACTTCTTGACGGTCCAAAGGGAAAC TCTAGATGCTCAGACTTTTCACACAAGAATAATCAGGTTCTGTTCCATAAACTCTGGATTGCATTCCTACATGGAAATGCCTCTGGAGTG TATTCTCACAGAAAAGAGAAAAAAGAGATCCACAAAGAAGGAAGTGTTTAATATACTTCAGGCTGCGTATGTCAGCAAGCCTGGGGCCCA GCTTGCTAGACAAATAGGAGCCAGCCTGAATGATGACATTCTTTTCGGGGTGTTCGCACAAAGCAAGCCAGATTCTGCCGAACCAATGGA TCGATCTGCCATGTGTGCATTCCCTATCAAATATGTCAACGACTTCTTCAACAAGATCGTCAACAAAAACAATGTGAGATGTCTCCAGCA TTTTTACGGACCCAATCATGAGCACTGCTTTAATAGGACACTTCTGAGAAATTCATCAGGCTGTGAAGCGCGCCGTGATGAATATCGAAC AGAGTTTACCACAGCTTTGCAGCGCGTTGACTTATTCATGGGTCAATTCAGCGAAGTCCTCTTAACATCTATATCCACCTTCATTAAAGG AGACCTCACCATAGCTAATCTTGGGACATCAGAGGGTCGCTTCATGCAGGTTGTGGTTTCTCGATCAGGACCATCAACCCCTCATGTGAA TTTTCTCCTGGACTCCCATCCAGTGTCTCCAGAAGTGATTGTGGAGCATACATTAAACCAAAATGGCTACACACTGGTTATCACTGGGAA GAAGATCACGAAGATCCCATTGAATGGCTTGGGCTGCAGACATTTCCAGTCCTGCAGTCAATGCCTCTCTGCCCCACCCTTTGTTCAGTG TGGCTGGTGCCACGACAAATGTGTGCGATCGGAGGAATGCCTGAGCGGGACATGGACTCAACAGATCTGTCTGCCTGCAATCTACAAGGT TTTCCCAAATAGTGCACCCCTTGAAGGAGGGACAAGGCTGACCATATGTGGCTGGGACTTTGGATTTCGGAGGAATAATAAATTTGATTT AAAGAAAACTAGAGTTCTCCTTGGAAATGAGAGCTGCACCTTGACTTTAAGTGAGAGCACGATGAATACATTGAAATGCACAGTTGGTCC TGCCATGAATAAGCATTTCAATATGTCCATAATTATTTCAAATGGCCACGGGACAACACAATACAGTACATTCTCCTATGTGGATCCTGT AATAACAAGTATTTCGCCGAAATACGGTCCTATGGCTGGTGGCACTTTACTTACTTTAACTGGAAATTACCTAAACAGTGGGAATTCTAG ACACATTTCAATTGGTGGAAAAACATGTACTTTAAAAAGTGTGTCAAACAGTATTCTTGAATGTTATACCCCAGCCCAAACCATTTCAAC TGAGTTTGCTGTTAAATTGAAAATTGACTTAGCCAACCGAGAGACAAGCATCTTCAGTTACCGTGAAGATCCCATTGTCTATGAAATTCA TCCAACCAAATCTTTTATTAGTACTTGGTGGAAAGAACCTCTCAACATTGTCAGTTTTCTATTTTGCTTTGCCAGTGGTGGGAGCACAAT AACAGGTGTTGGGAAAAACCTGAATTCAGTTAGTGTCCCGAGAATGGTCATAAATGTGCATGAAGCAGGAAGGAACTTTACAGTGGTGCG TATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAATTTAATGAGGTTTTCAATGATGTTCGGTTACTGCTTAATAATGACAATCT TCTCAGGGAAGGAGCAGCCCATGCATTTGCACAGTATAACTTGGACCAGTTTACTCCAGTAAAAATTGAAGGTTATGAAGATCAGGTATT GATAACAGAACATGGCGACTTGGGAAATGGAAAGTTTTTGGATCCAAAGAACAGAATCTGTTTTAAATTTGATCACTTAAGGAAGGAGGC AACTGATCCAAGACCCTGTGAAGTAGAAAATGCAGTTGAATCATGGAGAACTTCAGTAGAAACTGCTCTGAGAGCTTACGTAAAAGAACA TTACCCGAATGGAGTCTGCACTGAATGGTCGTTGGAGGTCAGAATGGAAGTTTACAATCACTCCTTCAACCACTCAAGTGGTTGGCATCT TGAAAATTCAGGTTCATTATTATGAAGATGGTAATGTTCAGCTAGTGAGTCATAAAGATATACAAGATTCCCTAACAGTGTCTAATGAAG TGCAAACAGCAAAAGAATTTATAAAGATTGTAGAAGCTGCAGAAAATGAATACCAGACTGCCATCAGTGAGAATTATCAGACAATGTCGG ACACTACTTTCAAAGCCTTACGTCGACAGTTGCCAGTTACACGCACTAAGATTGATTGGAACAAGATCCTTAGCTACAAGATTGGCAAAG AGATGCAGAATGCATAAGATGAACATTGCATGACCGGATCATTTTAGTGTCTTTGCGTTAAAAAATCATTGCAAAAGTATTCTGAACTGT CAAGCTGCCCAGTCAGATGGGCTGTTGCCATTTAAAATCACTGTAATTAATTAGTTTGATTAGAGCACAAAGCTTAGCTAATCAACCATT ATTTTTCATTTTGTTTGTTCTAAGAGGATTGAAAATCAGTTTAGTTTAAATGTCTTTCTGTTAGGCCTTTCTTTCTTACAATGAAGAGAT GATTCTTCTAGTTTATGGTTAAAAGTTTTTGAAGTGTCTCAAAAATATTTTACTAACTGTAACCCTAAAATTGATGTCTTTTGGTTTATG AAATCAGTAATTTTTGATATTTCCCCAGTTCTTTTTAATGGGGTCAATAATGGACATTCTAGTTTAAGGTGGTTGATGGATTTAGCCATA TATGCTGCTAAAGAAATTGTCTACCTTTTCTTCCTCACCTGTTCCATTTATGTAAAGTTGAGATTAGAGGGAAAGCATTTTCTATATCAA >53019_53019_2_MET-CAPZA2_MET_chr7_116399544_ENST00000318493_CAPZA2_chr7_116528181_ENST00000458284_length(amino acids)=965AA_BP=0 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVL EHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLD AQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDL TIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAM NKHFNMSIIISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVVRIA AKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATD -------------------------------------------------------------- >53019_53019_3_MET-CAPZA2_MET_chr7_116399544_ENST00000318493_CAPZA2_chr7_116528181_ENST00000490693_length(transcript)=3363nt_BP=2605nt GCCCTCGCCGCCCGCGGCGCCCCGAGCGCTTTGTGAGCAGATGCGGAGCCGAGTGGAGGGCGCGAGCCAGATGCGGGGCGACAGCTGACT TGCTGAGAGGAGGCGGGGAGGCGCGGAGCGCGCGTGTGGTCCTTGCGCCGCTGACTTCTCCACTGGTTCCTGGGCACCGAAAGATAAACC TCTCATAATGAAGGCCCCCGCTGTGCTTGCACCTGGCATCCTCGTGCTCCTGTTTACCTTGGTGCAGAGGAGCAATGGGGAGTGTAAAGA GGCACTAGCAAAGTCCGAGATGAATGTGAATATGAAGTATCAGCTTCCCAACTTCACCGCGGAAACACCCATCCAGAATGTCATTCTACA TGAGCATCACATTTTCCTTGGTGCCACTAACTACATTTATGTTTTAAATGAGGAAGACCTTCAGAAGGTTGCTGAGTACAAGACTGGGCC TGTGCTGGAACACCCAGATTGTTTCCCATGTCAGGACTGCAGCAGCAAAGCCAATTTATCAGGAGGTGTTTGGAAAGATAACATCAACAT GGCTCTAGTTGTCGACACCTACTATGATGATCAACTCATTAGCTGTGGCAGCGTCAACAGAGGGACCTGCCAGCGACATGTCTTTCCCCA CAATCATACTGCTGACATACAGTCGGAGGTTCACTGCATATTCTCCCCACAGATAGAAGAGCCCAGCCAGTGTCCTGACTGTGTGGTGAG CGCCCTGGGAGCCAAAGTCCTTTCATCTGTAAAGGACCGGTTCATCAACTTCTTTGTAGGCAATACCATAAATTCTTCTTATTTCCCAGA TCATCCATTGCATTCGATATCAGTGAGAAGGCTAAAGGAAACGAAAGATGGTTTTATGTTTTTGACGGACCAGTCCTACATTGATGTTTT ACCTGAGTTCAGAGATTCTTACCCCATTAAGTATGTCCATGCCTTTGAAAGCAACAATTTTATTTACTTCTTGACGGTCCAAAGGGAAAC TCTAGATGCTCAGACTTTTCACACAAGAATAATCAGGTTCTGTTCCATAAACTCTGGATTGCATTCCTACATGGAAATGCCTCTGGAGTG TATTCTCACAGAAAAGAGAAAAAAGAGATCCACAAAGAAGGAAGTGTTTAATATACTTCAGGCTGCGTATGTCAGCAAGCCTGGGGCCCA GCTTGCTAGACAAATAGGAGCCAGCCTGAATGATGACATTCTTTTCGGGGTGTTCGCACAAAGCAAGCCAGATTCTGCCGAACCAATGGA TCGATCTGCCATGTGTGCATTCCCTATCAAATATGTCAACGACTTCTTCAACAAGATCGTCAACAAAAACAATGTGAGATGTCTCCAGCA TTTTTACGGACCCAATCATGAGCACTGCTTTAATAGGACACTTCTGAGAAATTCATCAGGCTGTGAAGCGCGCCGTGATGAATATCGAAC AGAGTTTACCACAGCTTTGCAGCGCGTTGACTTATTCATGGGTCAATTCAGCGAAGTCCTCTTAACATCTATATCCACCTTCATTAAAGG AGACCTCACCATAGCTAATCTTGGGACATCAGAGGGTCGCTTCATGCAGGTTGTGGTTTCTCGATCAGGACCATCAACCCCTCATGTGAA TTTTCTCCTGGACTCCCATCCAGTGTCTCCAGAAGTGATTGTGGAGCATACATTAAACCAAAATGGCTACACACTGGTTATCACTGGGAA GAAGATCACGAAGATCCCATTGAATGGCTTGGGCTGCAGACATTTCCAGTCCTGCAGTCAATGCCTCTCTGCCCCACCCTTTGTTCAGTG TGGCTGGTGCCACGACAAATGTGTGCGATCGGAGGAATGCCTGAGCGGGACATGGACTCAACAGATCTGTCTGCCTGCAATCTACAAGGT TTTCCCAAATAGTGCACCCCTTGAAGGAGGGACAAGGCTGACCATATGTGGCTGGGACTTTGGATTTCGGAGGAATAATAAATTTGATTT AAAGAAAACTAGAGTTCTCCTTGGAAATGAGAGCTGCACCTTGACTTTAAGTGAGAGCACGATGAATACATTGAAATGCACAGTTGGTCC TGCCATGAATAAGCATTTCAATATGTCCATAATTATTTCAAATGGCCACGGGACAACACAATACAGTACATTCTCCTATGTGGATCCTGT AATAACAAGTATTTCGCCGAAATACGGTCCTATGGCTGGTGGCACTTTACTTACTTTAACTGGAAATTACCTAAACAGTGGGAATTCTAG ACACATTTCAATTGGTGGAAAAACATGTACTTTAAAAAGTGTGTCAAACAGTATTCTTGAATGTTATACCCCAGCCCAAACCATTTCAAC TGAGTTTGCTGTTAAATTGAAAATTGACTTAGCCAACCGAGAGACAAGCATCTTCAGTTACCGTGAAGATCCCATTGTCTATGAAATTCA TCCAACCAAATCTTTTATTAGTACTTGGTGGAAAGAACCTCTCAACATTGTCAGTTTTCTATTTTGCTTTGCCAGTGGTGGGAGCACAAT AACAGGTGTTGGGAAAAACCTGAATTCAGTTAGTGTCCCGAGAATGGTCATAAATGTGCATGAAGCAGGAAGGAACTTTACAGTGGTGCG TATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAATTTAATGAGGTTTTCAATGATGTTCGGTTACTGCTTAATAATGACAATCT TCTCAGGGAAGGAGCAGCCCATGCATTTGCACAGTATAACTTGGACCAGTTTACTCCAGTAAAAATTGAAGGTTATGAAGATCAGGTATT GATAACAGAACATGGCGACTTGGGAAATGGAAAGTTTTTGGATCCAAAGAACAGAATCTGTTTTAAATTTGATCACTTAAGGAAGGAGGC AACTGATCCAAGACCCTGTGAAGTAGAAAATGCAGTTGAATCATGGAGAACTTCAGTAGAAACTGCTCTGAGAGCTTACGTAAAAGAACA TTACCCGAATGGAGTCTGCACTGTAAGTCATCAGTAGCAGCTTTGTGTGTGTGTTTTGTGTAAATGTGAGTCTTTAGCGTCTCTTAAAAT TTACAGTAACTTACAGAATTGACATTGTATAATTTGTCATTTTTTTCCTTAAATATTTCTAAGAATGTTTACTATTTTTTCAAGAAATTC TGGATAATAAATAGATATACTAGGATGGCTTAAAATAGAGAAATGGTTGTACCTTGATTTAAATCCATGTAGAAATTCTAATACATTGAT TAAAGGAGCAGGATATGGTGAGATTCTGTAATCTTATGTTCATGACTCGTCTCAGTTTAGATCAAAGTTATTTTTATTAAGTCACAGAAA >53019_53019_3_MET-CAPZA2_MET_chr7_116399544_ENST00000318493_CAPZA2_chr7_116528181_ENST00000490693_length(amino acids)=939AA_BP=0 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVL EHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLD AQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDL TIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAM NKHFNMSIIISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISTWWKEPLNIVSFLFCFASGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVVRIA AKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATD -------------------------------------------------------------- >53019_53019_4_MET-CAPZA2_MET_chr7_116399544_ENST00000397752_CAPZA2_chr7_116528181_ENST00000361183_length(transcript)=7568nt_BP=2564nt AGGTGACCCGGAGGCCCTCGCCGCCCGCGGCGCCCCGAGCGCTTTGTGAGCAGATGCGGAGCCGAGTGGAGGGCGCGAGCCAGATGCGGG GCGACAGCTGACTTGCTGAGAGGAGGCGGGGAGGCGCGGAGCGCGCGTGTGGTCCTTGCGCCGCTGACTTCTCCACTGGTTCCTGGGCAC CGAAAGATAAACCTCTCATAATGAAGGCCCCCGCTGTGCTTGCACCTGGCATCCTCGTGCTCCTGTTTACCTTGGTGCAGAGGAGCAATG GGGAGTGTAAAGAGGCACTAGCAAAGTCCGAGATGAATGTGAATATGAAGTATCAGCTTCCCAACTTCACCGCGGAAACACCCATCCAGA ATGTCATTCTACATGAGCATCACATTTTCCTTGGTGCCACTAACTACATTTATGTTTTAAATGAGGAAGACCTTCAGAAGGTTGCTGAGT ACAAGACTGGGCCTGTGCTGGAACACCCAGATTGTTTCCCATGTCAGGACTGCAGCAGCAAAGCCAATTTATCAGGAGGTGTTTGGAAAG ATAACATCAACATGGCTCTAGTTGTCGACACCTACTATGATGATCAACTCATTAGCTGTGGCAGCGTCAACAGAGGGACCTGCCAGCGAC ATGTCTTTCCCCACAATCATACTGCTGACATACAGTCGGAGGTTCACTGCATATTCTCCCCACAGATAGAAGAGCCCAGCCAGTGTCCTG ACTGTGTGGTGAGCGCCCTGGGAGCCAAAGTCCTTTCATCTGTAAAGGACCGGTTCATCAACTTCTTTGTAGGCAATACCATAAATTCTT CTTATTTCCCAGATCATCCATTGCATTCGATATCAGTGAGAAGGCTAAAGGAAACGAAAGATGGTTTTATGTTTTTGACGGACCAGTCCT ACATTGATGTTTTACCTGAGTTCAGAGATTCTTACCCCATTAAGTATGTCCATGCCTTTGAAAGCAACAATTTTATTTACTTCTTGACGG TCCAAAGGGAAACTCTAGATGCTCAGACTTTTCACACAAGAATAATCAGGTTCTGTTCCATAAACTCTGGATTGCATTCCTACATGGAAA TGCCTCTGGAGTGTATTCTCACAGAAAAGAGAAAAAAGAGATCCACAAAGAAGGAAGTGTTTAATATACTTCAGGCTGCGTATGTCAGCA AGCCTGGGGCCCAGCTTGCTAGACAAATAGGAGCCAGCCTGAATGATGACATTCTTTTCGGGGTGTTCGCACAAAGCAAGCCAGATTCTG CCGAACCAATGGATCGATCTGCCATGTGTGCATTCCCTATCAAATATGTCAACGACTTCTTCAACAAGATCGTCAACAAAAACAATGTGA GATGTCTCCAGCATTTTTACGGACCCAATCATGAGCACTGCTTTAATAGGACACTTCTGAGAAATTCATCAGGCTGTGAAGCGCGCCGTG ATGAATATCGAACAGAGTTTACCACAGCTTTGCAGCGCGTTGACTTATTCATGGGTCAATTCAGCGAAGTCCTCTTAACATCTATATCCA CCTTCATTAAAGGAGACCTCACCATAGCTAATCTTGGGACATCAGAGGGTCGCTTCATGCAGGTTGTGGTTTCTCGATCAGGACCATCAA CCCCTCATGTGAATTTTCTCCTGGACTCCCATCCAGTGTCTCCAGAAGTGATTGTGGAGCATACATTAAACCAAAATGGCTACACACTGG TTATCACTGGGAAGAAGATCACGAAGATCCCATTGAATGGCTTGGGCTGCAGACATTTCCAGTCCTGCAGTCAATGCCTCTCTGCCCCAC CCTTTGTTCAGTGTGGCTGGTGCCACGACAAATGTGTGCGATCGGAGGAATGCCTGAGCGGGACATGGACTCAACAGATCTGTCTGCCTG CAATCTACAAGGTTTTCCCAAATAGTGCACCCCTTGAAGGAGGGACAAGGCTGACCATATGTGGCTGGGACTTTGGATTTCGGAGGAATA ATAAATTTGATTTAAAGAAAACTAGAGTTCTCCTTGGAAATGAGAGCTGCACCTTGACTTTAAGTGAGAGCACGATGAATACATTGAAAT GCACAGTTGGTCCTGCCATGAATAAGCATTTCAATATGTCCATAATTATTTCAAATGGCCACGGGACAACACAATACAGTACATTCTCCT ATGTGGATCCTGTAATAACAAGTATTTCGCCGAAATACGGTCCTATGGCTGGTGGCACTTTACTTACTTTAACTGGAAATTACCTAAACA GTGGGAATTCTAGACACATTTCAATTGGTGGAAAAACATGTACTTTAAAAAGTGTGTCAAACAGTATTCTTGAATGTTATACCCCAGCCC AAACCATTTCAACTGAGTTTGCTGTTAAATTGAAAATTGACTTAGCCAACCGAGAGACAAGCATCTTCAGTTACCGTGAAGATCCCATTG TCTATGAAATTCATCCAACCAAATCTTTTATTAGTGGTGGGAGCACAATAACAGGTGTTGGGAAAAACCTGAATTCAGTTAGTGTCCCGA GAATGGTCATAAATGTGCATGAAGCAGGAAGGAACTTTACAGTGGTGCGTATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAAT TTAATGAGGTTTTCAATGATGTTCGGTTACTGCTTAATAATGACAATCTTCTCAGGGAAGGAGCAGCCCATGCATTTGCACAGTATAACT TGGACCAGTTTACTCCAGTAAAAATTGAAGGTTATGAAGATCAGGTATTGATAACAGAACATGGCGACTTGGGAAATGGAAAGTTTTTGG ATCCAAAGAACAGAATCTGTTTTAAATTTGATCACTTAAGGAAGGAGGCAACTGATCCAAGACCCTGTGAAGTAGAAAATGCAGTTGAAT CATGGAGAACTTCAGTAGAAACTGCTCTGAGAGCTTACGTAAAAGAACATTACCCGAATGGAGTCTGCACTGTGTATGGCAAAAAAATAG ATGGACAGCAAACCATTATTGCATGCATAGAAAGCCATCAGTTCCAAGCAAAAAATTTTTGGAATGGTCGTTGGAGGTCAGAATGGAAGT TTACAATCACTCCTTCAACCACTCAAGTGGTTGGCATCTTGAAAATTCAGGTTCATTATTATGAAGATGGTAATGTTCAGCTAGTGAGTC ATAAAGATATACAAGATTCCCTAACAGTGTCTAATGAAGTGCAAACAGCAAAAGAATTTATAAAGATTGTAGAAGCTGCAGAAAATGAAT ACCAGACTGCCATCAGTGAGAATTATCAGACAATGTCGGACACTACTTTCAAAGCCTTACGTCGACAGTTGCCAGTTACACGCACTAAGA TTGATTGGAACAAGATCCTTAGCTACAAGATTGGCAAAGAGATGCAGAATGCATAAGATGAACATTGCATGACCGGATCATTTTAGTGTC TTTGCGTTAAAAAATCATTGCAAAAGTATTCTGAACTGTCAAGCTGCCCAGTCAGATGGGCTGTTGCCATTTAAAATCACTGTAATTAAT TAGTTTGATTAGAGCACAAAGCTTAGCTAATCAACCATTATTTTTCATTTTGTTTGTTCTAAGAGGATTGAAAATCAGTTTAGTTTAAAT GTCTTTCTGTTAGGCCTTTCTTTCTTACAATGAAGAGATGATTCTTCTAGTTTATGGTTAAAAGTTTTTGAAGTGTCTCAAAAATATTTT ACTAACTGTAACCCTAAAATTGATGTCTTTTGGTTTATGAAATCAGTAATTTTTGATATTTCCCCAGTTCTTTTTAATGGGGTCAATAAT GGACATTCTAGTTTAAGGTGGTTGATGGATTTAGCCATATATGCTGCTAAAGAAATTGTCTACCTTTTCTTCCTCACCTGTTCCATTTAT GTAAAGTTGAGATTAGAGGGAAAGCATTTTCTATATCAATTGTGTTTAAACCTTTCAAGAAGGTTATTTAGCTAGCTTAGTGTTGAACTA AATTTTTTTTAAACAAGGCAAGGTCTAATGCTGTTTTGAGATTCTGAAATTAATGAAAATACTTATTTCAGAAATGCATTTAATGCTTTT TTTCTTGTGACAGTTACGCAAATCAGCTTGAATTCCATATGTCCCTGAGTTATTTTTATCATAAAGCCACAAATGTATTATAACAAGGCA AATTGTAATATATATAATCCTGAACTCATGACCATGTCTCGGTTTATTTTTTTTTTCTTGGATTGAAAAGTACTGAAATTCAATGTGACA TTAAAATGCAAATTTTCCTATTTATTTGAGTAGAAAATCACTTACCAGTGAGCATATATATTTTAAAATACTTTCTTTGGATATTGTAAT TCTTAACTGGTTGTAAATTAGAAAAGCTGGGATTACATATGGTGTGCGGTTACAGTCTAAATTTTTTCATCCTCCTATGCATCATAAGCA TGTTTGTAATATTTTCAAAAATAGTTCTACTGATGCTACAGGAATTTCAAGCCTGTGGTGAATGTTAGTATTTACCATAGGGAGTGAAGT GGAGTTATGGTTTCATTCAATAGAGTATTGCTGATTATACTTGAGTGGAATCCTTTCCTCACGTACTCCCACAGACGTCTGGGCCTGGAA ATTTTTTTTTTATTTTATTTTATTGTTTTTTTTTTTAGAAAAACACCACTTTTATTATGTACAATAAAATATTTCATTAGCTTGAATTGT ATAGATTTTTAAAAATTCAATGAAAGCATGTTGTTTAATTTCTTTTTAAAATCACTGTTGGGCTTTGAAAGCATTGAGAATATAATATGA AATTATGACATTTTGTCTAAATCATCTTTTCTTTAGTTTTAAAATACAAGTTTTGGCACATTGGGATTCCTAAAGAAAATGAATTGGTAA CATTAATTATCTGTTCCTTTTTAAAATATATATATTTGAAAGTTTGATGATGGTGAACTAAATACTAGATCTAATTGACAAGCTTAGTTG TATCAGTTAGGCCATCATGAGTTTCTATCCCATGAAAGTCATCAATTTCCTATCTCTGTTCTAGTCTGGAATGCATTACTGAAAATGTAT GCAACTGTTTTTAAGGTGATTTGCTTGTGAGACGGAAGATTTATCAAAAATAATTTAGAACAGGCTGGGCGCGGTGGCTCACATCTGTAA TCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACGGGGTCAGGAGATTGAGACCACCCTGACTAACACAGTGAAACCCTGTCTCTACT AAAAATACAAAAAATTAGCCGGGTGTGGTGACAGGCGCTTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGG GAGGCGGAGCTCGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAATAATAATAATA ATAATAATAATATAATTTAGAACAGTCTGAAATAATGATGGCACAGAATAGTCTTTTATAGTATAAGAATGGCATTTATTAGGCAGGGCA CAGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATG CTGAAACCCCGTCTCTACTAAAAACAAAAAAAAATTAGCCGGGGATGGTGATGCGCGCCTGTAATCCCAACTACTCAGGAGGCTGAGACA GGAGAATCATTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCAGAGATCGAGCCACTGTACTCCAGCCTGGGTGACACAGGGAGCCTCTGT CTCAAAATAATAATAATAATAAAAGAATGGCATTTATTAAAGTGAAAGAAGAATGGAAACCCAGAGTATCCTATAGCTCAGGGATGTAAT TTTAGTAGGAGACATTATGGCTGCTTTGCTGAGTAGGCTGAAGTGTGGTGGCAAAGGCATAATCAGGGAGAACAGCTAGGAGACTACTGC AGTAATCTAGTTGAGAGAGCATGCTGGCTTGGACTGAGGTGGTTGCTGTAGAGGTGGTATAAAGCAGTGAGGTCTAGGTATATCCTAAAG GTAAAATCAGCAAGACCTGGGGAGAGTTTGGTCATGGAGTGTGAGATAAAGAGAACCATGTCTGGGGCTGGAGAAATTGAGGAAGATTCT TGTAGGAGCAAGTTGGTTTGGAGAAGAAGGCTGGTCAGGAGCTCAGTTTTCTATTCAAAGGAGAAATATCTCATGTAGCAGTTAGATACA GGAGACAGGAACTAGAGGAAAGCTCTGGGCTAGAAGAATGGGAAAGTGCATGAACCTGGAAACAATTTTATAGGCAGACAGGATGAAGGA CCTCAAGGTTAGTGATAATGAATTTAAAGTAAATGAGACCAATGATGAGCATGGCTGTATGTTTTTCTTCAACCGTGTAAAGCTGTTTGG GTGCAGGCATAGAGTAGATGAAATAAATTTCACCAGGGCTGTGGTTTTGCCCAGAGTGAATGACCACATGAAGAGGGGCAGGGTATGATG ATGGTCTGTGGAATTTCAGCTGGGTAAGCAGGGAAGTGAGGGCTTGAGACGGGGGGAGGGATAGTGAAAATGTACAACCAGTGGATTATA GGTGTGTTAAAGTAGGGGAACTAGAAAGAATGACCTGGAAATGTAAGAAGTGGGCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACT TTAGGAGGCTGAGGTGGGTGGATCATGAGGTCCAGAGATCAAGACCATCCTGGCCAATATGGTGCAACCCCATCTCTACTAAAAATACAA AAATTAGCTGGGCGTGGTGGTGTGCCTGTAGTCCCAGCTACTAGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGATGCGAAGGTTG CAGTGAGCCGAGATTGTGCCACTGCACTCCAGGCTGGCGACAGAGCGAGACTCTGTCCCAAAAAAAAAAAAAAGTGGTGGGCTGGCCACG ATGGCTCACGCCTATAATCCCAGCACTTTGGGAGGCCACGGCAAGTGGATCATTTAAGGTCAGGAGTTCAAGACCAGTCTGGCTAATATG ATGAAACCCCTTCTGTATTAAAAATACAAATATTAGCCGGGCATGGTGGCACATGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGG AGAATCTTTGAACCCAGGAAGTGACAGTTACAACGAGCGGAGACTGTGCCACTTCACTGCAGCCTGGGTGACAGGGTGAGAGTCTGTCTC AAAAAAAGAAAAAGGAAATGTAAGAAGTGGTGATTGGAGAATGGTGTGCTTAATTAAAATTGAGGTTTTGAGGAGTTACTAGTAATGACA AATATGACCAACGGAGTGACTGGCTGAGGGGAGAGAGGAGAGGACTTAAGCAACTGTGCCACTCAGCATTGGAAAGGTCACCTCTGTGAC ATTAAAATCAAGAATTCTGATAGAAGTAAGAGTTCTGGCATGAGTGGTGCTTTTCCAGAGTACACTTGGATATATGATTACATTTTAATA AGTTATATAAATATGCAGATATTCATGCGGCTTTTCCTCATTTGGGATTTTGGAAACTAAAATAGTAGTAAGAGCATTAAAAAAAAGATG >53019_53019_4_MET-CAPZA2_MET_chr7_116399544_ENST00000397752_CAPZA2_chr7_116528181_ENST00000361183_length(amino acids)=1061AA_BP=0 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVL EHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLD AQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDL TIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAM NKHFNMSIIISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVVRIAAKFIIHAPPGEFNEVFND VRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVE TALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDS -------------------------------------------------------------- >53019_53019_5_MET-CAPZA2_MET_chr7_116399544_ENST00000397752_CAPZA2_chr7_116528181_ENST00000458284_length(transcript)=3895nt_BP=2564nt AGGTGACCCGGAGGCCCTCGCCGCCCGCGGCGCCCCGAGCGCTTTGTGAGCAGATGCGGAGCCGAGTGGAGGGCGCGAGCCAGATGCGGG GCGACAGCTGACTTGCTGAGAGGAGGCGGGGAGGCGCGGAGCGCGCGTGTGGTCCTTGCGCCGCTGACTTCTCCACTGGTTCCTGGGCAC CGAAAGATAAACCTCTCATAATGAAGGCCCCCGCTGTGCTTGCACCTGGCATCCTCGTGCTCCTGTTTACCTTGGTGCAGAGGAGCAATG GGGAGTGTAAAGAGGCACTAGCAAAGTCCGAGATGAATGTGAATATGAAGTATCAGCTTCCCAACTTCACCGCGGAAACACCCATCCAGA ATGTCATTCTACATGAGCATCACATTTTCCTTGGTGCCACTAACTACATTTATGTTTTAAATGAGGAAGACCTTCAGAAGGTTGCTGAGT ACAAGACTGGGCCTGTGCTGGAACACCCAGATTGTTTCCCATGTCAGGACTGCAGCAGCAAAGCCAATTTATCAGGAGGTGTTTGGAAAG ATAACATCAACATGGCTCTAGTTGTCGACACCTACTATGATGATCAACTCATTAGCTGTGGCAGCGTCAACAGAGGGACCTGCCAGCGAC ATGTCTTTCCCCACAATCATACTGCTGACATACAGTCGGAGGTTCACTGCATATTCTCCCCACAGATAGAAGAGCCCAGCCAGTGTCCTG ACTGTGTGGTGAGCGCCCTGGGAGCCAAAGTCCTTTCATCTGTAAAGGACCGGTTCATCAACTTCTTTGTAGGCAATACCATAAATTCTT CTTATTTCCCAGATCATCCATTGCATTCGATATCAGTGAGAAGGCTAAAGGAAACGAAAGATGGTTTTATGTTTTTGACGGACCAGTCCT ACATTGATGTTTTACCTGAGTTCAGAGATTCTTACCCCATTAAGTATGTCCATGCCTTTGAAAGCAACAATTTTATTTACTTCTTGACGG TCCAAAGGGAAACTCTAGATGCTCAGACTTTTCACACAAGAATAATCAGGTTCTGTTCCATAAACTCTGGATTGCATTCCTACATGGAAA TGCCTCTGGAGTGTATTCTCACAGAAAAGAGAAAAAAGAGATCCACAAAGAAGGAAGTGTTTAATATACTTCAGGCTGCGTATGTCAGCA AGCCTGGGGCCCAGCTTGCTAGACAAATAGGAGCCAGCCTGAATGATGACATTCTTTTCGGGGTGTTCGCACAAAGCAAGCCAGATTCTG CCGAACCAATGGATCGATCTGCCATGTGTGCATTCCCTATCAAATATGTCAACGACTTCTTCAACAAGATCGTCAACAAAAACAATGTGA GATGTCTCCAGCATTTTTACGGACCCAATCATGAGCACTGCTTTAATAGGACACTTCTGAGAAATTCATCAGGCTGTGAAGCGCGCCGTG ATGAATATCGAACAGAGTTTACCACAGCTTTGCAGCGCGTTGACTTATTCATGGGTCAATTCAGCGAAGTCCTCTTAACATCTATATCCA CCTTCATTAAAGGAGACCTCACCATAGCTAATCTTGGGACATCAGAGGGTCGCTTCATGCAGGTTGTGGTTTCTCGATCAGGACCATCAA CCCCTCATGTGAATTTTCTCCTGGACTCCCATCCAGTGTCTCCAGAAGTGATTGTGGAGCATACATTAAACCAAAATGGCTACACACTGG TTATCACTGGGAAGAAGATCACGAAGATCCCATTGAATGGCTTGGGCTGCAGACATTTCCAGTCCTGCAGTCAATGCCTCTCTGCCCCAC CCTTTGTTCAGTGTGGCTGGTGCCACGACAAATGTGTGCGATCGGAGGAATGCCTGAGCGGGACATGGACTCAACAGATCTGTCTGCCTG CAATCTACAAGGTTTTCCCAAATAGTGCACCCCTTGAAGGAGGGACAAGGCTGACCATATGTGGCTGGGACTTTGGATTTCGGAGGAATA ATAAATTTGATTTAAAGAAAACTAGAGTTCTCCTTGGAAATGAGAGCTGCACCTTGACTTTAAGTGAGAGCACGATGAATACATTGAAAT GCACAGTTGGTCCTGCCATGAATAAGCATTTCAATATGTCCATAATTATTTCAAATGGCCACGGGACAACACAATACAGTACATTCTCCT ATGTGGATCCTGTAATAACAAGTATTTCGCCGAAATACGGTCCTATGGCTGGTGGCACTTTACTTACTTTAACTGGAAATTACCTAAACA GTGGGAATTCTAGACACATTTCAATTGGTGGAAAAACATGTACTTTAAAAAGTGTGTCAAACAGTATTCTTGAATGTTATACCCCAGCCC AAACCATTTCAACTGAGTTTGCTGTTAAATTGAAAATTGACTTAGCCAACCGAGAGACAAGCATCTTCAGTTACCGTGAAGATCCCATTG TCTATGAAATTCATCCAACCAAATCTTTTATTAGTGGTGGGAGCACAATAACAGGTGTTGGGAAAAACCTGAATTCAGTTAGTGTCCCGA GAATGGTCATAAATGTGCATGAAGCAGGAAGGAACTTTACAGTGGTGCGTATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAAT TTAATGAGGTTTTCAATGATGTTCGGTTACTGCTTAATAATGACAATCTTCTCAGGGAAGGAGCAGCCCATGCATTTGCACAGTATAACT TGGACCAGTTTACTCCAGTAAAAATTGAAGGTTATGAAGATCAGGTATTGATAACAGAACATGGCGACTTGGGAAATGGAAAGTTTTTGG ATCCAAAGAACAGAATCTGTTTTAAATTTGATCACTTAAGGAAGGAGGCAACTGATCCAAGACCCTGTGAAGTAGAAAATGCAGTTGAAT CATGGAGAACTTCAGTAGAAACTGCTCTGAGAGCTTACGTAAAAGAACATTACCCGAATGGAGTCTGCACTGAATGGTCGTTGGAGGTCA GAATGGAAGTTTACAATCACTCCTTCAACCACTCAAGTGGTTGGCATCTTGAAAATTCAGGTTCATTATTATGAAGATGGTAATGTTCAG CTAGTGAGTCATAAAGATATACAAGATTCCCTAACAGTGTCTAATGAAGTGCAAACAGCAAAAGAATTTATAAAGATTGTAGAAGCTGCA GAAAATGAATACCAGACTGCCATCAGTGAGAATTATCAGACAATGTCGGACACTACTTTCAAAGCCTTACGTCGACAGTTGCCAGTTACA CGCACTAAGATTGATTGGAACAAGATCCTTAGCTACAAGATTGGCAAAGAGATGCAGAATGCATAAGATGAACATTGCATGACCGGATCA TTTTAGTGTCTTTGCGTTAAAAAATCATTGCAAAAGTATTCTGAACTGTCAAGCTGCCCAGTCAGATGGGCTGTTGCCATTTAAAATCAC TGTAATTAATTAGTTTGATTAGAGCACAAAGCTTAGCTAATCAACCATTATTTTTCATTTTGTTTGTTCTAAGAGGATTGAAAATCAGTT TAGTTTAAATGTCTTTCTGTTAGGCCTTTCTTTCTTACAATGAAGAGATGATTCTTCTAGTTTATGGTTAAAAGTTTTTGAAGTGTCTCA AAAATATTTTACTAACTGTAACCCTAAAATTGATGTCTTTTGGTTTATGAAATCAGTAATTTTTGATATTTCCCCAGTTCTTTTTAATGG GGTCAATAATGGACATTCTAGTTTAAGGTGGTTGATGGATTTAGCCATATATGCTGCTAAAGAAATTGTCTACCTTTTCTTCCTCACCTG TTCCATTTATGTAAAGTTGAGATTAGAGGGAAAGCATTTTCTATATCAATTGTGTTTAAACCTTTCAAGAAGGTTATTTAGCTAGCTTAG >53019_53019_5_MET-CAPZA2_MET_chr7_116399544_ENST00000397752_CAPZA2_chr7_116528181_ENST00000458284_length(amino acids)=947AA_BP=0 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVL EHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLD AQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDL TIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAM NKHFNMSIIISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVVRIAAKFIIHAPPGEFNEVFND VRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVE -------------------------------------------------------------- >53019_53019_6_MET-CAPZA2_MET_chr7_116399544_ENST00000397752_CAPZA2_chr7_116528181_ENST00000490693_length(transcript)=3322nt_BP=2564nt AGGTGACCCGGAGGCCCTCGCCGCCCGCGGCGCCCCGAGCGCTTTGTGAGCAGATGCGGAGCCGAGTGGAGGGCGCGAGCCAGATGCGGG GCGACAGCTGACTTGCTGAGAGGAGGCGGGGAGGCGCGGAGCGCGCGTGTGGTCCTTGCGCCGCTGACTTCTCCACTGGTTCCTGGGCAC CGAAAGATAAACCTCTCATAATGAAGGCCCCCGCTGTGCTTGCACCTGGCATCCTCGTGCTCCTGTTTACCTTGGTGCAGAGGAGCAATG GGGAGTGTAAAGAGGCACTAGCAAAGTCCGAGATGAATGTGAATATGAAGTATCAGCTTCCCAACTTCACCGCGGAAACACCCATCCAGA ATGTCATTCTACATGAGCATCACATTTTCCTTGGTGCCACTAACTACATTTATGTTTTAAATGAGGAAGACCTTCAGAAGGTTGCTGAGT ACAAGACTGGGCCTGTGCTGGAACACCCAGATTGTTTCCCATGTCAGGACTGCAGCAGCAAAGCCAATTTATCAGGAGGTGTTTGGAAAG ATAACATCAACATGGCTCTAGTTGTCGACACCTACTATGATGATCAACTCATTAGCTGTGGCAGCGTCAACAGAGGGACCTGCCAGCGAC ATGTCTTTCCCCACAATCATACTGCTGACATACAGTCGGAGGTTCACTGCATATTCTCCCCACAGATAGAAGAGCCCAGCCAGTGTCCTG ACTGTGTGGTGAGCGCCCTGGGAGCCAAAGTCCTTTCATCTGTAAAGGACCGGTTCATCAACTTCTTTGTAGGCAATACCATAAATTCTT CTTATTTCCCAGATCATCCATTGCATTCGATATCAGTGAGAAGGCTAAAGGAAACGAAAGATGGTTTTATGTTTTTGACGGACCAGTCCT ACATTGATGTTTTACCTGAGTTCAGAGATTCTTACCCCATTAAGTATGTCCATGCCTTTGAAAGCAACAATTTTATTTACTTCTTGACGG TCCAAAGGGAAACTCTAGATGCTCAGACTTTTCACACAAGAATAATCAGGTTCTGTTCCATAAACTCTGGATTGCATTCCTACATGGAAA TGCCTCTGGAGTGTATTCTCACAGAAAAGAGAAAAAAGAGATCCACAAAGAAGGAAGTGTTTAATATACTTCAGGCTGCGTATGTCAGCA AGCCTGGGGCCCAGCTTGCTAGACAAATAGGAGCCAGCCTGAATGATGACATTCTTTTCGGGGTGTTCGCACAAAGCAAGCCAGATTCTG CCGAACCAATGGATCGATCTGCCATGTGTGCATTCCCTATCAAATATGTCAACGACTTCTTCAACAAGATCGTCAACAAAAACAATGTGA GATGTCTCCAGCATTTTTACGGACCCAATCATGAGCACTGCTTTAATAGGACACTTCTGAGAAATTCATCAGGCTGTGAAGCGCGCCGTG ATGAATATCGAACAGAGTTTACCACAGCTTTGCAGCGCGTTGACTTATTCATGGGTCAATTCAGCGAAGTCCTCTTAACATCTATATCCA CCTTCATTAAAGGAGACCTCACCATAGCTAATCTTGGGACATCAGAGGGTCGCTTCATGCAGGTTGTGGTTTCTCGATCAGGACCATCAA CCCCTCATGTGAATTTTCTCCTGGACTCCCATCCAGTGTCTCCAGAAGTGATTGTGGAGCATACATTAAACCAAAATGGCTACACACTGG TTATCACTGGGAAGAAGATCACGAAGATCCCATTGAATGGCTTGGGCTGCAGACATTTCCAGTCCTGCAGTCAATGCCTCTCTGCCCCAC CCTTTGTTCAGTGTGGCTGGTGCCACGACAAATGTGTGCGATCGGAGGAATGCCTGAGCGGGACATGGACTCAACAGATCTGTCTGCCTG CAATCTACAAGGTTTTCCCAAATAGTGCACCCCTTGAAGGAGGGACAAGGCTGACCATATGTGGCTGGGACTTTGGATTTCGGAGGAATA ATAAATTTGATTTAAAGAAAACTAGAGTTCTCCTTGGAAATGAGAGCTGCACCTTGACTTTAAGTGAGAGCACGATGAATACATTGAAAT GCACAGTTGGTCCTGCCATGAATAAGCATTTCAATATGTCCATAATTATTTCAAATGGCCACGGGACAACACAATACAGTACATTCTCCT ATGTGGATCCTGTAATAACAAGTATTTCGCCGAAATACGGTCCTATGGCTGGTGGCACTTTACTTACTTTAACTGGAAATTACCTAAACA GTGGGAATTCTAGACACATTTCAATTGGTGGAAAAACATGTACTTTAAAAAGTGTGTCAAACAGTATTCTTGAATGTTATACCCCAGCCC AAACCATTTCAACTGAGTTTGCTGTTAAATTGAAAATTGACTTAGCCAACCGAGAGACAAGCATCTTCAGTTACCGTGAAGATCCCATTG TCTATGAAATTCATCCAACCAAATCTTTTATTAGTGGTGGGAGCACAATAACAGGTGTTGGGAAAAACCTGAATTCAGTTAGTGTCCCGA GAATGGTCATAAATGTGCATGAAGCAGGAAGGAACTTTACAGTGGTGCGTATAGCAGCAAAATTCATCATTCATGCCCCTCCTGGAGAAT TTAATGAGGTTTTCAATGATGTTCGGTTACTGCTTAATAATGACAATCTTCTCAGGGAAGGAGCAGCCCATGCATTTGCACAGTATAACT TGGACCAGTTTACTCCAGTAAAAATTGAAGGTTATGAAGATCAGGTATTGATAACAGAACATGGCGACTTGGGAAATGGAAAGTTTTTGG ATCCAAAGAACAGAATCTGTTTTAAATTTGATCACTTAAGGAAGGAGGCAACTGATCCAAGACCCTGTGAAGTAGAAAATGCAGTTGAAT CATGGAGAACTTCAGTAGAAACTGCTCTGAGAGCTTACGTAAAAGAACATTACCCGAATGGAGTCTGCACTGTAAGTCATCAGTAGCAGC TTTGTGTGTGTGTTTTGTGTAAATGTGAGTCTTTAGCGTCTCTTAAAATTTACAGTAACTTACAGAATTGACATTGTATAATTTGTCATT TTTTTCCTTAAATATTTCTAAGAATGTTTACTATTTTTTCAAGAAATTCTGGATAATAAATAGATATACTAGGATGGCTTAAAATAGAGA AATGGTTGTACCTTGATTTAAATCCATGTAGAAATTCTAATACATTGATTAAAGGAGCAGGATATGGTGAGATTCTGTAATCTTATGTTC >53019_53019_6_MET-CAPZA2_MET_chr7_116399544_ENST00000397752_CAPZA2_chr7_116528181_ENST00000490693_length(amino acids)=921AA_BP=0 MKAPAVLAPGILVLLFTLVQRSNGECKEALAKSEMNVNMKYQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVL EHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSVNRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSAL GAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLD AQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRS AMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSISTFIKGDL TIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHTLNQNGYTLVITGKKITKIPLNGLGCRHFQSCSQCLSAPPFVQCGW CHDKCVRSEECLSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAM NKHFNMSIIISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEF AVKLKIDLANRETSIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVVRIAAKFIIHAPPGEFNEVFND VRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRPCEVENAVESWRTSVE -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for MET-CAPZA2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000318493 | + | 10 | 21 | 1320_1359 | 806.0 | 1409.0 | MUC20 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000397752 | + | 10 | 21 | 1320_1359 | 788.0 | 1391.0 | MUC20 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000436117 | + | 1 | 9 | 1320_1359 | 0.0 | 765.0 | MUC20 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000318493 | + | 10 | 21 | 1212_1390 | 806.0 | 1409.0 | RANBP9 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000397752 | + | 10 | 21 | 1212_1390 | 788.0 | 1391.0 | RANBP9 |
| Hgene | MET | chr7:116399544 | chr7:116528181 | ENST00000436117 | + | 1 | 9 | 1212_1390 | 0.0 | 765.0 | RANBP9 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for MET-CAPZA2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for MET-CAPZA2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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