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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:METTL21B-GLI1 (FusionGDB2 ID:53086)

Fusion Gene Summary for METTL21B-GLI1

check button Fusion gene summary
Fusion gene informationFusion gene name: METTL21B-GLI1
Fusion gene ID: 53086
HgeneTgene
Gene symbol

METTL21B

GLI1

Gene ID

25895

2735

Gene nameEEF1A lysine methyltransferase 3GLI family zinc finger 1
SynonymsFAM119B|METTL21BGLI|PAPA8|PPD1
Cytomap

12q14.1

12q13.3

Type of geneprotein-codingprotein-coding
DescriptionEEF1A lysine methyltransferase 3family with sequence similarity 119, member Bhepatocellular carcinoma-associated antigen 557ahepatocellularcarcinoma-associated antigen HCA557amethyltransferase like 21Bmethyltransferase-like protein 21Bprotein-lysinezinc finger protein GLI1GLI-Kruppel family member GLI1glioma-associated oncogene 1glioma-associated oncogene homolog 1 (zinc finger protein)oncogene GLI
Modification date2020031320200313
UniProtAcc.

P08151

Ensembl transtripts involved in fusion geneENST00000300209, ENST00000333012, 
ENST00000548256, ENST00000552307, 
ENST00000551420, 		ENST00000228682, 
ENST00000543426, ENST00000546141, 
Fusion gene scores* DoF score17 X 5 X 8=68011 X 12 X 4=528
# samples 2110
** MAII scorelog2(21/680*10)=-1.69514541847158
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/528*10)=-2.40053792958373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: METTL21B [Title/Abstract] AND GLI1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMETTL21B(58166911)-GLI1(57857448), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMETTL21B

GO:0018022

peptidyl-lysine methylation

28108655

TgeneGLI1

GO:0001649

osteoblast differentiation

12165851

TgeneGLI1

GO:0007224

smoothened signaling pathway

19878745

TgeneGLI1

GO:0009913

epidermal cell differentiation

12165851

TgeneGLI1

GO:0045740

positive regulation of DNA replication

12165851

TgeneGLI1

GO:0045880

positive regulation of smoothened signaling pathway

17035233

TgeneGLI1

GO:0045893

positive regulation of transcription, DNA-templated

11238441|12165851|17035233

TgeneGLI1

GO:0045944

positive regulation of transcription by RNA polymerase II

9118802|10693759|12165851

TgeneGLI1

GO:0060045

positive regulation of cardiac muscle cell proliferation

28583401

TgeneGLI1

GO:1902808

positive regulation of cell cycle G1/S phase transition

28583401


check buttonFusion gene breakpoints across METTL21B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across GLI1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-TM-A84B-01AMETTL21Bchr12

58166910

+GLI1chr12

57857447

+
ChimerDB4LGGTCGA-TM-A84B-01AMETTL21Bchr12

58166910

+GLI1chr12

57858455

+
ChimerDB4LGGTCGA-TM-A84B-01AMETTL21Bchr12

58166911

-GLI1chr12

57857448

+
ChimerDB4LGGTCGA-TM-A84B-01AMETTL21Bchr12

58166911

+GLI1chr12

57857448

+
ChimerDB4LGGTCGA-TM-A84BMETTL21Bchr12

58166911

+GLI1chr12

57857447

+
ChimerDB4LGGTCGA-TM-A84BMETTL21Bchr12

58166911

+GLI1chr12

57857448

+
ChimerDB4LGGTCGA-TM-A84BMETTL21Bchr12

58166911

+GLI1chr12

57858455

+
ChimerDB4LGGTCGA-TM-A84BMETTL21Bchr12

58166911

+GLI1chr12

57858456

+
ChimerDB4LGGTCGA-TM-A84BMETTL21Bchr12

58168550

+GLI1chr12

57857447

+


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Fusion Gene ORF analysis for METTL21B-GLI1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000300209ENST00000228682METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5CDS-5UTRENST00000300209ENST00000228682METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5CDS-5UTRENST00000300209ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5CDS-5UTRENST00000300209ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5CDS-5UTRENST00000300209ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5CDS-5UTRENST00000300209ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57858456

+
5CDS-5UTRENST00000300209ENST00000543426METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5CDS-5UTRENST00000300209ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5CDS-5UTRENST00000300209ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57858456

+
5CDS-5UTRENST00000300209ENST00000546141METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5CDS-5UTRENST00000300209ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5CDS-5UTRENST00000300209ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5CDS-5UTRENST00000333012ENST00000228682METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5CDS-5UTRENST00000333012ENST00000228682METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5CDS-5UTRENST00000333012ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5CDS-5UTRENST00000333012ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5CDS-5UTRENST00000333012ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5CDS-5UTRENST00000333012ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57858456

+
5CDS-5UTRENST00000333012ENST00000228682METTL21Bchr12

58168550

+GLI1chr12

57857447

+
5CDS-5UTRENST00000333012ENST00000543426METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5CDS-5UTRENST00000333012ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5CDS-5UTRENST00000333012ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57858456

+
5CDS-5UTRENST00000333012ENST00000546141METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5CDS-5UTRENST00000333012ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5CDS-5UTRENST00000333012ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5CDS-5UTRENST00000333012ENST00000546141METTL21Bchr12

58168550

+GLI1chr12

57857447

+
5CDS-5UTRENST00000548256ENST00000228682METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5CDS-5UTRENST00000548256ENST00000228682METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5CDS-5UTRENST00000548256ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5CDS-5UTRENST00000548256ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5CDS-5UTRENST00000548256ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5CDS-5UTRENST00000548256ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57858456

+
5CDS-5UTRENST00000548256ENST00000228682METTL21Bchr12

58168550

+GLI1chr12

57857447

+
5CDS-5UTRENST00000548256ENST00000543426METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5CDS-5UTRENST00000548256ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5CDS-5UTRENST00000548256ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57858456

+
5CDS-5UTRENST00000548256ENST00000546141METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5CDS-5UTRENST00000548256ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5CDS-5UTRENST00000548256ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5CDS-5UTRENST00000548256ENST00000546141METTL21Bchr12

58168550

+GLI1chr12

57857447

+
5CDS-5UTRENST00000552307ENST00000228682METTL21Bchr12

58168550

+GLI1chr12

57857447

+
5CDS-5UTRENST00000552307ENST00000546141METTL21Bchr12

58168550

+GLI1chr12

57857447

+
5CDS-intronENST00000300209ENST00000543426METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5CDS-intronENST00000300209ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5CDS-intronENST00000300209ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5CDS-intronENST00000300209ENST00000546141METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5CDS-intronENST00000300209ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5CDS-intronENST00000300209ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57858456

+
5CDS-intronENST00000333012ENST00000543426METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5CDS-intronENST00000333012ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5CDS-intronENST00000333012ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5CDS-intronENST00000333012ENST00000543426METTL21Bchr12

58168550

+GLI1chr12

57857447

+
5CDS-intronENST00000333012ENST00000546141METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5CDS-intronENST00000333012ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5CDS-intronENST00000333012ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57858456

+
5CDS-intronENST00000548256ENST00000543426METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5CDS-intronENST00000548256ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5CDS-intronENST00000548256ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5CDS-intronENST00000548256ENST00000543426METTL21Bchr12

58168550

+GLI1chr12

57857447

+
5CDS-intronENST00000548256ENST00000546141METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5CDS-intronENST00000548256ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5CDS-intronENST00000548256ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57858456

+
5CDS-intronENST00000552307ENST00000543426METTL21Bchr12

58168550

+GLI1chr12

57857447

+
5UTR-5UTRENST00000551420ENST00000228682METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5UTR-5UTRENST00000551420ENST00000228682METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5UTR-5UTRENST00000551420ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5UTR-5UTRENST00000551420ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5UTR-5UTRENST00000551420ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5UTR-5UTRENST00000551420ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57858456

+
5UTR-5UTRENST00000551420ENST00000543426METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5UTR-5UTRENST00000551420ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5UTR-5UTRENST00000551420ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57858456

+
5UTR-5UTRENST00000551420ENST00000546141METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5UTR-5UTRENST00000551420ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5UTR-5UTRENST00000551420ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5UTR-intronENST00000551420ENST00000543426METTL21Bchr12

58166910

+GLI1chr12

57857447

+
5UTR-intronENST00000551420ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57857448

+
5UTR-intronENST00000551420ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57857447

+
5UTR-intronENST00000551420ENST00000546141METTL21Bchr12

58166910

+GLI1chr12

57858455

+
5UTR-intronENST00000551420ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57858455

+
5UTR-intronENST00000551420ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57858456

+
intron-5UTRENST00000300209ENST00000228682METTL21Bchr12

58168550

+GLI1chr12

57857447

+
intron-5UTRENST00000300209ENST00000546141METTL21Bchr12

58168550

+GLI1chr12

57857447

+
intron-5UTRENST00000551420ENST00000228682METTL21Bchr12

58168550

+GLI1chr12

57857447

+
intron-5UTRENST00000551420ENST00000546141METTL21Bchr12

58168550

+GLI1chr12

57857447

+
intron-5UTRENST00000552307ENST00000228682METTL21Bchr12

58166910

+GLI1chr12

57857447

+
intron-5UTRENST00000552307ENST00000228682METTL21Bchr12

58166910

+GLI1chr12

57858455

+
intron-5UTRENST00000552307ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57857448

+
intron-5UTRENST00000552307ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57857447

+
intron-5UTRENST00000552307ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57858455

+
intron-5UTRENST00000552307ENST00000228682METTL21Bchr12

58166911

+GLI1chr12

57858456

+
intron-5UTRENST00000552307ENST00000543426METTL21Bchr12

58166910

+GLI1chr12

57858455

+
intron-5UTRENST00000552307ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57858455

+
intron-5UTRENST00000552307ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57858456

+
intron-5UTRENST00000552307ENST00000546141METTL21Bchr12

58166910

+GLI1chr12

57857447

+
intron-5UTRENST00000552307ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57857448

+
intron-5UTRENST00000552307ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57857447

+
intron-intronENST00000300209ENST00000543426METTL21Bchr12

58168550

+GLI1chr12

57857447

+
intron-intronENST00000551420ENST00000543426METTL21Bchr12

58168550

+GLI1chr12

57857447

+
intron-intronENST00000552307ENST00000543426METTL21Bchr12

58166910

+GLI1chr12

57857447

+
intron-intronENST00000552307ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57857448

+
intron-intronENST00000552307ENST00000543426METTL21Bchr12

58166911

+GLI1chr12

57857447

+
intron-intronENST00000552307ENST00000546141METTL21Bchr12

58166910

+GLI1chr12

57858455

+
intron-intronENST00000552307ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57858455

+
intron-intronENST00000552307ENST00000546141METTL21Bchr12

58166911

+GLI1chr12

57858456

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for METTL21B-GLI1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for METTL21B-GLI1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:58166911/:57857448)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.GLI1

P08151

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Acts as a transcriptional activator (PubMed:19706761, PubMed:10806483, PubMed:19878745, PubMed:24311597, PubMed:24217340). Binds to the DNA consensus sequence 5'-GACCACCCA-3' (PubMed:2105456, PubMed:8378770, PubMed:24217340). Regulates the transcription of specific genes during normal development (PubMed:19706761). Plays a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling (PubMed:19706761, PubMed:28973407). Plays a role in cell proliferation and differentiation via its role in SHH signaling (PubMed:11238441, PubMed:28973407). {ECO:0000269|PubMed:10806483, ECO:0000269|PubMed:11238441, ECO:0000269|PubMed:19706761, ECO:0000269|PubMed:19878745, ECO:0000269|PubMed:2105456, ECO:0000269|PubMed:24217340, ECO:0000269|PubMed:24311597, ECO:0000269|PubMed:28973407, ECO:0000269|PubMed:8378770}.; FUNCTION: [Isoform 2]: Acts as a transcriptional activator, but activates a different set of genes than isoform 1. Activates expression of CD24, unlike isoform 1. Mediates SHH signaling. Promotes cancer cell migration. {ECO:0000269|PubMed:19706761}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for METTL21B-GLI1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for METTL21B-GLI1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for METTL21B-GLI1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for METTL21B-GLI1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource