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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:MEX3D-DOCK11 (FusionGDB2 ID:53156) |
Fusion Gene Summary for MEX3D-DOCK11 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MEX3D-DOCK11 | Fusion gene ID: 53156 | Hgene | Tgene | Gene symbol | MEX3D | DOCK11 | Gene ID | 399664 | 139818 |
| Gene name | mex-3 RNA binding family member D | dedicator of cytokinesis 11 | |
| Synonyms | MEX-3D|MEX3|OK/SW-cl.4|RKHD1|RNF193|TINO | ACG|ZIZ2|bB128O4.1 | |
| Cytomap | 19p13.3 | Xq24 | |
| Type of gene | protein-coding | protein-coding | |
| Description | RNA-binding protein MEX3DRING finger and KH domain-containing protein 1RING finger protein 193bcl-2 ARE RNA binding proteinring finger (C3HC4 type) and KH domain containing 1ring finger and KH domain containing 1 | dedicator of cytokinesis protein 11Activated Cdc42-associated guanine nucleotide exchange factor, ACGbB128O4.1.1 (novel protein)zizimin-2zizimin2 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q86XN8 | Q5JSL3 | |
| Ensembl transtripts involved in fusion gene | ENST00000388824, ENST00000402693, | ENST00000276202, ENST00000276204, | |
| Fusion gene scores | * DoF score | 4 X 2 X 3=24 | 11 X 12 X 7=924 |
| # samples | 5 | 13 | |
| ** MAII score | log2(5/24*10)=1.05889368905357 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(13/924*10)=-2.8293812283876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MEX3D [Title/Abstract] AND DOCK11 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | MEX3D(1567463)-DOCK11(117676688), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across MEX3D (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across DOCK11 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SARC | TCGA-HB-A3YV-01A | MEX3D | chr19 | 1567463 | - | DOCK11 | chrX | 117676688 | + |
| ChimerDB4 | SARC | TCGA-X9-A971-01A | MEX3D | chr19 | 1567463 | - | DOCK11 | chrX | 117676688 | + |
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Fusion Gene ORF analysis for MEX3D-DOCK11 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000388824 | ENST00000276202 | MEX3D | chr19 | 1567463 | - | DOCK11 | chrX | 117676688 | + |
| In-frame | ENST00000388824 | ENST00000276204 | MEX3D | chr19 | 1567463 | - | DOCK11 | chrX | 117676688 | + |
| In-frame | ENST00000402693 | ENST00000276202 | MEX3D | chr19 | 1567463 | - | DOCK11 | chrX | 117676688 | + |
| In-frame | ENST00000402693 | ENST00000276204 | MEX3D | chr19 | 1567463 | - | DOCK11 | chrX | 117676688 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000402693 | MEX3D | chr19 | 1567463 | - | ENST00000276204 | DOCK11 | chrX | 117676688 | + | 7083 | 595 | 619 | 6726 | 2035 |
| ENST00000402693 | MEX3D | chr19 | 1567463 | - | ENST00000276202 | DOCK11 | chrX | 117676688 | + | 7055 | 595 | 619 | 6714 | 2031 |
| ENST00000388824 | MEX3D | chr19 | 1567463 | - | ENST00000276204 | DOCK11 | chrX | 117676688 | + | 7083 | 595 | 619 | 6726 | 2035 |
| ENST00000388824 | MEX3D | chr19 | 1567463 | - | ENST00000276202 | DOCK11 | chrX | 117676688 | + | 7055 | 595 | 619 | 6714 | 2031 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000402693 | ENST00000276204 | MEX3D | chr19 | 1567463 | - | DOCK11 | chrX | 117676688 | + | 0.000450684 | 0.9995493 |
| ENST00000402693 | ENST00000276202 | MEX3D | chr19 | 1567463 | - | DOCK11 | chrX | 117676688 | + | 0.000775993 | 0.99922395 |
| ENST00000388824 | ENST00000276204 | MEX3D | chr19 | 1567463 | - | DOCK11 | chrX | 117676688 | + | 0.000450684 | 0.9995493 |
| ENST00000388824 | ENST00000276202 | MEX3D | chr19 | 1567463 | - | DOCK11 | chrX | 117676688 | + | 0.000775993 | 0.99922395 |
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Fusion Genomic Features for MEX3D-DOCK11 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for MEX3D-DOCK11 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:1567463/chrX:117676688) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MEX3D | DOCK11 |
| FUNCTION: RNA binding protein, may be involved in post-transcriptional regulatory mechanisms. {ECO:0000250}. | FUNCTION: Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42. {ECO:0000250|UniProtKB:A2AF47}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | DOCK11 | chr19:1567463 | chrX:117676688 | ENST00000276202 | 0 | 53 | 1609_2036 | 34 | 2074.0 | Domain | DOCKER | |
| Tgene | DOCK11 | chr19:1567463 | chrX:117676688 | ENST00000276202 | 0 | 53 | 165_272 | 34 | 2074.0 | Domain | PH | |
| Tgene | DOCK11 | chr19:1567463 | chrX:117676688 | ENST00000276202 | 0 | 53 | 640_818 | 34 | 2074.0 | Domain | C2 DOCK-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MEX3D | chr19:1567463 | chrX:117676688 | ENST00000388824 | - | 1 | 3 | 179_240 | 198 | 667.0 | Domain | KH 1 |
| Hgene | MEX3D | chr19:1567463 | chrX:117676688 | ENST00000388824 | - | 1 | 3 | 273_334 | 198 | 667.0 | Domain | KH 2 |
| Hgene | MEX3D | chr19:1567463 | chrX:117676688 | ENST00000402693 | - | 1 | 2 | 179_240 | 198 | 652.0 | Domain | KH 1 |
| Hgene | MEX3D | chr19:1567463 | chrX:117676688 | ENST00000402693 | - | 1 | 2 | 273_334 | 198 | 652.0 | Domain | KH 2 |
| Hgene | MEX3D | chr19:1567463 | chrX:117676688 | ENST00000388824 | - | 1 | 3 | 600_640 | 198 | 667.0 | Zinc finger | RING-type |
| Hgene | MEX3D | chr19:1567463 | chrX:117676688 | ENST00000402693 | - | 1 | 2 | 600_640 | 198 | 652.0 | Zinc finger | RING-type |
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Fusion Gene Sequence for MEX3D-DOCK11 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >53156_53156_1_MEX3D-DOCK11_MEX3D_chr19_1567463_ENST00000388824_DOCK11_chrX_117676688_ENST00000276202_length(transcript)=7055nt_BP=595nt ATGCCCAGCTCGCTCGGCCAGCCCGACGGCGGCGGGGGCGGGGGCGGCGGCGGCGGCGGCGTGGGGGCGGCGGGGGAGGACCCCGGACCC GGACCTGCGCCCCCGCCCGAGGGCGCCCAGGAGGCCGCGCCCGCGCCCCGGCCGCCGCCCGAACCCGACGACGCGGCCGCCGCGCTCCGC CTGGCGCTGGACCAGCTGTCGGCGCTCGGGCTGGGGGGCGCTGGCGACACGGACGAGGAGGGGGCGGCCGGGGACGGCGCAGCGGCGGCG GGGGGCGCGGACGGCGGGGCGGCTCCGGAGCCTGTGCCCCCCGACGGACCTGAGGCCGGCGCGCCCCCGACCCTGGCCCCCGCCGTGGCC CCCGGGTCGCTGCCGCTGCTGGACCCCAACGCGAGTCCCCCGCCGCCGCCGCCGCCCCGGCCGTCGCCCCCCGACGTGTTCGCGGGCTTC GCGCCCCACCCCGCGGCCCTGGGGCCCCCGACGCTGCTGGCCGACCAGATGAGCGTGATCGGCAGCCGCAAGAAAAGCGTCAACATGACC GAGTGCGTCCCGGTGCCCAGCTCCGAGCACGTCGCCGAGATCGTGGGTCGCCAGGGAAAAGGCCAAAGTTGTTGAGCCCCTGGACTATGA GAATGTTATTGCCCAAAGAAAAACCCAGATTTACAGCGACCCCCTCCGAGATCTGCTTATGTTCCCAATGGAAGATATATCTATCTCGGT GATAGGTCGTCAACGCAGAACGGTGCAGTCTACTGTACCAGAAGATGCTGAAAAGAGGGCCCAGAGTTTATTTGTTAAAGAGTGTATTAA AACCTATAGCACAGATTGGCACGTGGTAAACTACAAGTATGAGGACTTCTCTGGGGACTTTCGAATGTTGCCATGTAAATCTTTGAGACC AGAAAAGATTCCTAATCATGTATTTGAGATAGATGAAGACTGTGAGAAAGATGAGGACTCATCTTCTTTATGTTCTCAGAAGGGTGGTGT GATAAAACAAGGCTGGTTGCATAAAGCAAATGTAAATAGTACCATCACAGTAACCATGAAGGTATTCAAGAGACGATATTTTTACTTGAC CCAACTTCCTGACGGTTCATATATTCTCAATTCCTATAAAGATGAGAAAAATTCAAAAGAATCGAAAGGTTGCATCTACTTGGACGCCTG CATTGATGTTGTTCAGTGCCCCAAAATGCGCCGTCATGCTTTTGAACTCAAGATGTTAGATAAATATAGCCATTATCTGGCTGCTGAAAC TGAGCAGGAAATGGAGGAATGGTTGATAACTTTGAAAAAGATTATTCAGATCAACACCGACAGTTTAGTTCAAGAAAAAAAGGAGACGGT AGAAACAGCACAAGATGATGAAACTAGCAGCCAAGGAAAAGCCGAGAACATCATGGCAAGTTTGGAAAGGAGCATGCATCCGGAACTGAT GAAGTATGGAAGAGAAACTGAACAACTAAACAAACTCAGTAGAGGAGATGGAAGACAGAATCTCTTTTCTTTTGATTCAGAAGTTCAGAG GTTGGACTTTTCAGGAATTGAACCTGATATAAAGCCATTTGAAGAAAAATGCAATAAACGTTTCCTGGTGAATTGCCATGATTTAACTTT CAATATCTTGGGCCAAATTGGAGACAATGCAAAAGGACCACCCACAAATGTTGAGCCCTTTTTTATCAATCTTGCCTTATTTGATGTAAA GAACAATTGTAAGATTTCAGCAGACTTTCATGTAGACCTGAATCCCCCATCTGTCCGTGAAATGCTGTGGGGCTCTTCAACCCAACTGGC CAGTGACGGTAGCCCAAAGGGCTCTTCACCCGAATCTTACATTCATGGAATTGCCGAATCTCAGTTACGCTACATACAACAGGGAATTTT CTCAGTGACGAATCCACATCCTGAAATTTTTCTAGTTGCCAGAATTGAAAAGGTACTACAGGGAAACATTACACACTGTGCAGAACCCTA TATCAAAAATTCTGATCCAGTAAAGACGGCCCAGAAGGTGCACAGGACAGCTAAACAAGTGTGTAGCCGCCTTGGACAATACAGAATGCC CTTCGCTTGGGCTGCCAGACCCATTTTCAAAGATACTCAAGGCTCTCTTGATCTGGATGGGAGATTTTCTCCTCTGTATAAACAAGACAG TAGCAAGCTTTCAAGTGAAGACATTCTCAAGTTGCTCTCAGAATATAAGAAGCCAGAAAAGACCAAACTGCAGATTATTCCTGGGCAGCT AAACATCACAGTAGAATGTGTTCCTGTGGATTTATCAAATTGTATTACTTCTTCATATGTGCCCTTGAAGCCTTTTGAAAAGAATTGCCA AAATATTACTGTGGAGGTTGAAGAGTTTGTTCCAGAAATGACAAAATATTGTTATCCATTTACTATTTACAAAAACCATCTGTATGTATA TCCCCTGCAATTAAAATACGATAGCCAGAAAACATTTGCCAAGGCAAGGAACATTGCAGTCTGTGTGGAATTCCGGGATTCAGATGAAAG TGACGCTAGTGCCCTAAAGTGTATTTATGGAAAACCTGCAGGGTCTGTTTTTACCACAAATGCTTATGCTGTTGTCTCGCATCACAACCA AAATCCAGAGTTCTATGATGAGATTAAAATTGAGCTTCCCATTCACCTACATCAAAAACATCATTTGCTTTTCACTTTTTATCATGTAAG TTGTGAAATTAACACAAAGGGAACAACCAAAAAGCAAGACACAGTTGAAACTCCAGTTGGGTTTGCCTGGGTACCTTTGCTGAAAGATGG TAGAATCATCACATTTGAGCAGCAGCTGCCAGTTTCCGCCAATCTTCCCCCAGGCTACTTGAATCTGAATGATGCAGAATCAAGAAGGCA ATGTAACGTGGATATTAAATGGGTAGATGGTGCAAAGCCTTTGTTGAAGATTAAAAGCCACTTAGAATCTACCATTTACACTCAAGATCT GCATGTGCACAAATTCTTCCATCATTGCCAGCTGATTCAGTCAGGCTCGAAAGAAGTTCCAGGGGAGCTCATTAAATATTTAAAGTGTTT GCATGCCATGGAGATCCAAGTCATGATACAGTTTCTACCTGTAATTCTTATGCAACTCTTCCGAGTTCTCACAAATATGACCCATGAAGA TGACGTTCCTATCAACTGCACCATGGTTCTCTTACATATTGTATCAAAGTGCCATGAAGAAGGCTTGGATAGTTATCTAAGATCATTCAT AAAGTATAGCTTCCGACCTGAAAAACCGAGTGCTCCTCAGGCCCAGCTGATACATGAAACCCTGGCTACTACGATGATAGCAATATTGAA ACAGTCTGCAGATTTTTTATCAATAAACAAATTGCTAAAGTACTCATGGTTTTTCTTTGAAATAATTGCAAAGTCAATGGCCACATACTT GTTGGAAGAGAATAAGATTAAGCTTCCCCGAGGCCAGAGATTTCCCGAGACATATCATCATGTCTTACATTCACTGCTTCTTGCAATAAT TCCCCATGTGACTATTCGGTATGCGGAGATTCCCGATGAGTCCAGAAATGTGAACTATAGTTTGGCTAGCTTCCTGAAGCGCTGTTTGAC ACTAATGGATAGAGGATTTATTTTCAATTTAATAAATGACTATATATCTGGATTCAGCCCCAAAGATCCTAAGGTTCTGGCTGAATACAA GTTTGAATTTCTGCAAACAATTTGCAATCACGAACATTACATTCCTCTGAACTTGCCAATGGCATTTGCAAAACCTAAACTGCAGCGGGT TCAAGATTCAAATCTTGAATACAGTTTATCAGATGAGTATTGCAAGCATCACTTCTTGGTTGGTCTACTTCTGAGGGAAACTTCCATTGC TCTTCAGGACAATTATGAGATCAGATATACAGCTATCTCTGTTATAAAGAATCTTTTGATAAAACATGCATTTGACACAAGATACCAGCA CAAGAACCAACAAGCCAAAATAGCACAATTGTACCTCCCCTTTGTTGGACTACTTTTGGAAAATATACAGCGATTAGCAGGTCGAGATAC CTTGTATTCTTGTGCAGCCATGCCTAATTCTGCATCCAGAGATGAGTTTCCATGTGGCTTTACTTCACCTGCCAATAGAGGGAGTCTGAG CACTGACAAAGACACCGCTTATGGGTCTTTTCAAAATGGACATGGAATTAAGAGAGAAGATTCAAGAGGTTCCCTCATCCCAGAAGGAGC AACAGGATTTCCAGATCAGGGCAACACTGGTGAAAATACCCGACAGAGTTCTACAAGGAGTAGTGTATCCCAGTATAACCGCCTGGATCA GTATGAAATCAGAAGCCTCCTGATGTGCTACCTGTATATAGTAAAAATGATTTCAGAAGATACTCTCTTAACTTACTGGAATAAAGTATC ACCTCAGGAGCTCATAAACATTCTTATACTTTTAGAAGTATGCTTGTTTCACTTTAGATATATGGGGAAAAGAAACATAGCAAGGGTGCA TGATGCCTGGCTGTCAAAACACTTCGGAATAGACCGAAAATCGCAAACCATGCCTGCTCTTCGAAACAGATCAGGAGTAATGCAGGCCCG GCTTCAGCATCTTAGTAGCCTAGAAAGTTCATTTACACTTAATCACAGTTCTACAACAACTGAAGCAGACATTTTCCACCAGGCACTTCT TGAAGGCAATACAGCTACTGAAGTTTCCCTAACAGTACTAGACACCATATCATTTTTCACTCAGTGCTTCAAGACCCAACTTTTAAATAA TGATGGCCATAACCCATTAATGAAAAAAGTGTTTGATATACATCTTGCTTTTCTTAAAAATGGACAATCTGAAGTGTCGCTGAAACATGT ATTTGCCTCACTGAGAGCTTTCATCAGTAAGTTTCCTTCAGCATTTTTCAAAGGAAGAGTAAACATGTGTGCTGCATTTTGCTATGAGGT TTTAAAGTGCTGCACATCGAAGATTAGCTCAACCAGGAATGAAGCATCTGCACTTTTGTATCTTTTGATGAGAAACAACTTTGAGTATAC CAAAAGGAAAACCTTTTTGAGGACACATCTACAGATAATAATTGCTGTAAGCCAACTGATAGCTGATGTAGCACTAAGCGGAGGATCAAG ATTTCAGGAGTCTTTATTCATTATCAATAATTTTGCAAATAGTGACAGACCTATGAAGGCAACTGCCTTTCCCGCAGAAGTCAAAGACTT GACCAAGAGAATCCGCACTGTTCTTATGGCCACTGCCCAAATGAAGGAGCATGAGAAAGACCCTGAAATGCTAATTGATCTCCAGTATAG CTTAGCCAAGTCCTATGCAAGCACCCCAGAGCTCAGGAAAACCTGGCTTGATAGCATGGCCAAGATTCATGTAAAAAATGGAGATTTTTC AGAGGCTGCGATGTGTTATGTCCATGTAGCAGCTCTAGTTGCAGAGTTTCTTCATCGAAAAAAATTATTTCCTAACGGATGTTCAGCGTT CAAGAAAATTACTCCCAATATAGATGAAGAAGGAGCAATGAAAGAAGATGCTGGGATGATGGATGTCCATTATAGTGAAGAGGTCTTGCT GGAGTTGCTAGAACAATGTGTGGATGGCTTATGGAAGGCAGAACGTTATGAAATAATTTCTGAGATTTCCAAGTTGATCGTTCCAATTTA TGAGAAACGTCGTGAGTTTGAGAAACTTACTCAAGTTTATAGAACTCTTCATGGAGCTTACACAAAAATTCTGGAAGTTATGCATACAAA AAAGAGACTTTTAGGCACTTTCTTCAGAGTTGCCTTTTATGGCCAATCTTTTTTTGAAGAAGAAGATGGAAAGGAGTACATCTATAAAGA ACCAAAGCTCACTGGCCTCTCAGAAATTTCCTTGAGACTTGTTAAACTTTATGGTGAAAAGTTTGGTACGGAGAATGTCAAAATAATTCA GGATTCAGACAAGGTAAATGCCAAAGAGCTTGATCCAAAATATGCTCATATACAAGTTACTTATGTGAAGCCTTACTTTGATGACAAAGA ACTCACAGAAAGGAAGACCGAGTTTGAAAGAAATCATAATATCAGCAGATTTGTTTTTGAGGCCCCTTACACTTTATCAGGCAAAAAACA GGGCTGTATAGAAGAACAGTGCAAACGCCGTACAATCTTGACAACTTCAAACTCGTTTCCTTACGTGAAGAAGAGGATTCCTATTAACTG TGAACAGCAGATTAATTTAAAACCAATTGATGTTGCCACTGATGAAATAAAAGATAAAACTGCAGAGCTGCAAAAGCTTTGCTCCTCTAC TGACGTGGACATGATTCAGCTCCAACTTAAATTGCAGGGCTGTGTTTCTGTGCAGGTCAATGCTGGTCCATTAGCATATGCAAGAGCTTT CTTAAATGACAGCCAAGCTAGCAAGTATCCACCTAAGAAAGTGAGTGAGTTGAAAGACATGTTTAGGAAATTTATACAAGCATGCAGCAT TGCACTTGAACTAAATGAGCGGCTAATTAAAGAAGATCAAGTTGAGTACCATGAAGGGCTAAAGTCAAATTTCAGAGACATGGTAAAAGA ATTATCTGACATTATCCATGAGCAGATATTACAAGAAGACACAATGCATTCTCCCTGGATGAGCAACACATTACATGTATTTTGTGCAAT TAGTGGTACATCAAGTGACCGAGGTTATGGTTCCCCAAGATACGCTGAAGTGTGAGGAAATGCAGATGTACGTGACAATGAGACTGACCT TTCTCAGGAATATTTGGAGCTGTGCAAATGTTAAAATTTAAAGATTTGATATACATGGAGTGTTTCTTCTCGACACCAAAATTTTCATGT GTTCCAACAGGGTGCTTACATATTTGTAAATAAGCAACTTGAAAGTGCCTGGAAAATTGCACCACTGTGCTTGGTTTGTACTTTTTTAGG TAAATCTATATGCTGAAAAGTAGAGCTCAAAAACAGTAGTTCAATTTGCTTAATTATTGCTTAAAATAATGGTACTATGTAAAATTGTAT >53156_53156_1_MEX3D-DOCK11_MEX3D_chr19_1567463_ENST00000388824_DOCK11_chrX_117676688_ENST00000276202_length(amino acids)=2031AA_BP= MDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCK SLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIY LDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERSMH PELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLAL FDVKNNCKISADFHVDLNPPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNITHC AEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQII PGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRD SDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPL LKDGRIITFEQQLPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKY LKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMI AILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLK RCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRE TSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFTSPANR GSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYW NKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFH QALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAF CYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAE VKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNG CSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEV MHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYF DDKELTERKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKL CSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRD -------------------------------------------------------------- >53156_53156_2_MEX3D-DOCK11_MEX3D_chr19_1567463_ENST00000388824_DOCK11_chrX_117676688_ENST00000276204_length(transcript)=7083nt_BP=595nt ATGCCCAGCTCGCTCGGCCAGCCCGACGGCGGCGGGGGCGGGGGCGGCGGCGGCGGCGGCGTGGGGGCGGCGGGGGAGGACCCCGGACCC GGACCTGCGCCCCCGCCCGAGGGCGCCCAGGAGGCCGCGCCCGCGCCCCGGCCGCCGCCCGAACCCGACGACGCGGCCGCCGCGCTCCGC CTGGCGCTGGACCAGCTGTCGGCGCTCGGGCTGGGGGGCGCTGGCGACACGGACGAGGAGGGGGCGGCCGGGGACGGCGCAGCGGCGGCG GGGGGCGCGGACGGCGGGGCGGCTCCGGAGCCTGTGCCCCCCGACGGACCTGAGGCCGGCGCGCCCCCGACCCTGGCCCCCGCCGTGGCC CCCGGGTCGCTGCCGCTGCTGGACCCCAACGCGAGTCCCCCGCCGCCGCCGCCGCCCCGGCCGTCGCCCCCCGACGTGTTCGCGGGCTTC GCGCCCCACCCCGCGGCCCTGGGGCCCCCGACGCTGCTGGCCGACCAGATGAGCGTGATCGGCAGCCGCAAGAAAAGCGTCAACATGACC GAGTGCGTCCCGGTGCCCAGCTCCGAGCACGTCGCCGAGATCGTGGGTCGCCAGGGAAAAGGCCAAAGTTGTTGAGCCCCTGGACTATGA GAATGTTATTGCCCAAAGAAAAACCCAGATTTACAGCGACCCCCTCCGAGATCTGCTTATGTTCCCAATGGAAGATATATCTATCTCGGT GATAGGTCGTCAACGCAGAACGGTGCAGTCTACTGTACCAGAAGATGCTGAAAAGAGGGCCCAGAGTTTATTTGTTAAAGAGTGTATTAA AACCTATAGCACAGATTGGCACGTGGTAAACTACAAGTATGAGGACTTCTCTGGGGACTTTCGAATGTTGCCATGTAAATCTTTGAGACC AGAAAAGATTCCTAATCATGTATTTGAGATAGATGAAGACTGTGAGAAAGATGAGGACTCATCTTCTTTATGTTCTCAGAAGGGTGGTGT GATAAAACAAGGCTGGTTGCATAAAGCAAATGTAAATAGTACCATCACAGTAACCATGAAGGTATTCAAGAGACGATATTTTTACTTGAC CCAACTTCCTGACGGTTCATATATTCTCAATTCCTATAAAGATGAGAAAAATTCAAAAGAATCGAAAGGTTGCATCTACTTGGACGCCTG CATTGATGTTGTTCAGTGCCCCAAAATGCGCCGTCATGCTTTTGAACTCAAGATGTTAGATAAATATAGCCATTATCTGGCTGCTGAAAC TGAGCAGGAAATGGAGGAATGGTTGATAACTTTGAAAAAGATTATTCAGATCAACACCGACAGTTTAGTTCAAGAAAAAAAGGAGACGGT AGAAACAGCACAAGATGATGAAACTAGCAGCCAAGGAAAAGCCGAGAACATCATGGCAAGTTTGGAAAGGAGCATGCATCCGGAACTGAT GAAGTATGGAAGAGAAACTGAACAACTAAACAAACTCAGTAGAGGAGATGGAAGACAGAATCTCTTTTCTTTTGATTCAGAAGTTCAGAG GTTGGACTTTTCAGGAATTGAACCTGATATAAAGCCATTTGAAGAAAAATGCAATAAACGTTTCCTGGTGAATTGCCATGATTTAACTTT CAATATCTTGGGCCAAATTGGAGACAATGCAAAAGGACCACCCACAAATGTTGAGCCCTTTTTTATCAATCTTGCCTTATTTGATGTAAA GAACAATTGTAAGATTTCAGCAGACTTTCATGTAGACCTGAATCCCCCATCTGTCCGTGAAATGCTGTGGGGCTCTTCAACCCAACTGGC CAGTGACGGTAGCCCAAAGGGCTCTTCACCCGAATCTTACATTCATGGAATTGCCGAATCTCAGTTACGCTACATACAACAGGGAATTTT CTCAGTGACGAATCCACATCCTGAAATTTTTCTAGTTGCCAGAATTGAAAAGGTACTACAGGGAAACATTACACACTGTGCAGAACCCTA TATCAAAAATTCTGATCCAGTAAAGACGGCCCAGAAGGTGCACAGGACAGCTAAACAAGTGTGTAGCCGCCTTGGACAATACAGAATGCC CTTCGCTTGGGCTGCCAGACCCATTTTCAAAGATACTCAAGGCTCTCTTGATCTGGATGGGAGATTTTCTCCTCTGTATAAACAAGACAG TAGCAAGCTTTCAAGTGAAGACATTCTCAAGTTGCTCTCAGAATATAAGAAGCCAGAAAAGACCAAACTGCAGATTATTCCTGGGCAGCT AAACATCACAGTAGAATGTGTTCCTGTGGATTTATCAAATTGTATTACTTCTTCATATGTGCCCTTGAAGCCTTTTGAAAAGAATTGCCA AAATATTACTGTGGAGGTTGAAGAGTTTGTTCCAGAAATGACAAAATATTGTTATCCATTTACTATTTACAAAAACCATCTGTATGTATA TCCCCTGCAATTAAAATACGATAGCCAGAAAACATTTGCCAAGGCAAGGAACATTGCAGTCTGTGTGGAATTCCGGGATTCAGATGAAAG TGACGCTAGTGCCCTAAAGTGTATTTATGGAAAACCTGCAGGGTCTGTTTTTACCACAAATGCTTATGCTGTTGTCTCGCATCACAACCA AAATCCAGAGTTCTATGATGAGATTAAAATTGAGCTTCCCATTCACCTACATCAAAAACATCATTTGCTTTTCACTTTTTATCATGTAAG TTGTGAAATTAACACAAAGGGAACAACCAAAAAGCAAGACACAGTTGAAACTCCAGTTGGGTTTGCCTGGGTACCTTTGCTGAAAGATGG TAGAATCATCACATTTGAGCAGCAGCTGCCAGTTTCCGCCAATCTTCCCCCAGGCTACTTGAATCTGAATGATGCAGAATCAAGAAGGCA ATGTAACGTGGATATTAAATGGGTAGATGGTGCAAAGCCTTTGTTGAAGATTAAAAGCCACTTAGAATCTACCATTTACACTCAAGATCT GCATGTGCACAAATTCTTCCATCATTGCCAGCTGATTCAGTCAGGCTCGAAAGAAGTTCCAGGGGAGCTCATTAAATATTTAAAGTGTTT GCATGCCATGGAGATCCAAGTCATGATACAGTTTCTACCTGTAATTCTTATGCAACTCTTCCGAGTTCTCACAAATATGACCCATGAAGA TGACGTTCCTATCAACTGCACCATGGTTCTCTTACATATTGTATCAAAGTGCCATGAAGAAGGCTTGGATAGTTATCTAAGATCATTCAT AAAGTATAGCTTCCGACCTGAAAAACCGAGTGCTCCTCAGGCCCAGCTGATACATGAAACCCTGGCTACTACGATGATAGCAATATTGAA ACAGTCTGCAGATTTTTTATCAATAAACAAATTGCTAAAGTACTCATGGTTTTTCTTTGAAATAATTGCAAAGTCAATGGCCACATACTT GTTGGAAGAGAATAAGATTAAGCTTCCCCGAGGCCAGAGATTTCCCGAGACATATCATCATGTCTTACATTCACTGCTTCTTGCAATAAT TCCCCATGTGACTATTCGGTATGCGGAGATTCCCGATGAGTCCAGAAATGTGAACTATAGTTTGGCTAGCTTCCTGAAGCGCTGTTTGAC ACTAATGGATAGAGGATTTATTTTCAATTTAATAAATGACTATATATCTGGATTCAGCCCCAAAGATCCTAAGGTTCTGGCTGAATACAA GTTTGAATTTCTGCAAACAATTTGCAATCACGAACATTACATTCCTCTGAACTTGCCAATGGCATTTGCAAAACCTAAACTGCAGCGGGT TCAAGATTCAAATCTTGAATACAGTTTATCAGATGAGTATTGCAAGCATCACTTCTTGGTTGGTCTACTTCTGAGGGAAACTTCCATTGC TCTTCAGGACAATTATGAGATCAGATATACAGCTATCTCTGTTATAAAGAATCTTTTGATAAAACATGCATTTGACACAAGATACCAGCA CAAGAACCAACAAGCCAAAATAGCACAATTGTACCTCCCCTTTGTTGGACTACTTTTGGAAAATATACAGCGATTAGCAGGTCGAGATAC CTTGTATTCTTGTGCAGCCATGCCTAATTCTGCATCCAGAGATGAGTTTCCATGTGGCTTTACTTCACCTGCCAATAGAGGGAGTCTGAG CACTGACAAAGACACCGCTTATGGGTCTTTTCAAAATGGACATGGAATTAAGAGAGAAGATTCAAGAGGTTCCCTCATCCCAGAAGGAGC AACAGGATTTCCAGATCAGGGCAACACTGGTGAAAATACCCGACAGAGTTCTACAAGGAGTAGTGTATCCCAGTATAACCGCCTGGATCA GTATGAAATCAGAAGCCTCCTGATGTGCTACCTGTATATAGTAAAAATGATTTCAGAAGATACTCTCTTAACTTACTGGAATAAAGTATC ACCTCAGGAGCTCATAAACATTCTTATACTTTTAGAAGTATGCTTGTTTCACTTTAGATATATGGGGAAAAGAAACATAGCAAGGGTGCA TGATGCCTGGCTGTCAAAACACTTCGGAATAGACCGAAAATCGCAAACCATGCCTGCTCTTCGAAACAGATCAGGAGTAATGCAGGCCCG GCTTCAGCATCTTAGTAGCCTAGAAAGTTCATTTACACTTAATCACAGTTCTACAACAACTGAAGCAGACATTTTCCACCAGGCACTTCT TGAAGGCAATACAGCTACTGAAGTTTCCCTAACAGTACTAGACACCATATCATTTTTCACTCAGTGCTTCAAGACCCAACTTTTAAATAA TGATGGCCATAACCCATTAATGAAAAAAGTGTTTGATATACATCTTGCTTTTCTTAAAAATGGACAATCTGAAGTGTCGCTGAAACATGT ATTTGCCTCACTGAGAGCTTTCATCAGTAAGTTTCCTTCAGCATTTTTCAAAGGAAGAGTAAACATGTGTGCTGCATTTTGCTATGAGGT TTTAAAGTGCTGCACATCGAAGATTAGCTCAACCAGGAATGAAGCATCTGCACTTTTGTATCTTTTGATGAGAAACAACTTTGAGTATAC CAAAAGGAAAACCTTTTTGAGGACACATCTACAGATAATAATTGCTGTAAGCCAACTGATAGCTGATGTAGCACTAAGCGGAGGATCAAG ATTTCAGGAGTCTTTATTCATTATCAATAATTTTGCAAATAGTGACAGACCTATGAAGGCAACTGCCTTTCCCGCAGAAGTCAAAGACTT GACCAAGAGAATCCGCACTGTTCTTATGGCCACTGCCCAAATGAAGGAGCATGAGAAAGACCCTGAAATGCTAATTGATCTCCAGTATAG CTTAGCCAAGTCCTATGCAAGCACCCCAGAGCTCAGGAAAACCTGGCTTGATAGCATGGCCAAGATTCATGTAAAAAATGGAGATTTTTC AGAGGCTGCGATGTGTTATGTCCATGTAGCAGCTCTAGTTGCAGAGTTTCTTCATCGAAAAAAATTATTTCCTAACGGATGTTCAGCGTT CAAGAAAATTACTCCCAATATAGATGAAGAAGGAGCAATGAAAGAAGATGCTGGGATGATGGATGTCCATTATAGTGAAGAGGTCTTGCT GGAGTTGCTAGAACAATGTGTGGATGGCTTATGGAAGGCAGAACGTTATGAAATAATTTCTGAGATTTCCAAGTTGATCGTTCCAATTTA TGAGAAACGTCGTGAGTTTGAGAAACTTACTCAAGTTTATAGAACTCTTCATGGAGCTTACACAAAAATTCTGGAAGTTATGCATACAAA AAAGAGACTTTTAGGCACTTTCTTCAGAGTTGCCTTTTATGGCCAATCTTTTTTTGAAGAAGAAGATGGAAAGGAGTACATCTATAAAGA ACCAAAGCTCACTGGCCTCTCAGAAATTTCCTTGAGACTTGTTAAACTTTATGGTGAAAAGTTTGGTACGGAGAATGTCAAAATAATTCA GGATTCAGACAAGGTAAATGCCAAAGAGCTTGATCCAAAATATGCTCATATACAAGTTACTTATGTGAAGCCTTACTTTGATGACAAAGA ACTCACAGAAAGGAAGACCGAGTTTGAAAGAAATCATAATATCAGCAGATTTGTTTTTGAGGCCCCTTACACTTTATCAGGCAAAAAACA GGGCTGTATAGAAGAACAGTGCAAACGCCGTACAATCTTGACAACTTCAAACTCGTTTCCTTACGTGAAGAAGAGGATTCCTATTAACTG TGAACAGCAGATTAATTTAAAACCAATTGATGTTGCCACTGATGAAATAAAAGATAAAACTGCAGAGCTGCAAAAGCTTTGCTCCTCTAC TGACGTGGACATGATTCAGCTCCAACTTAAATTGCAGGGCTGTGTTTCTGTGCAGGTCAATGCTGGTCCATTAGCATATGCAAGAGCTTT CTTAAATGACAGCCAAGCTAGCAAGTATCCACCTAAGAAAGTGAGTGAGTTGAAAGACATGTTTAGGAAATTTATACAAGCATGCAGCAT TGCACTTGAACTAAATGAGCGGCTAATTAAAGAAGATCAAGTTGAGTACCATGAAGGGCTAAAGTCAAATTTCAGAGACATGGTAAAAGA ATTATCTGACATTATCCATGAGCAGGCAAGTATTAGGATATTACAAGAAGACACAATGCATTCTCCCTGGATGAGCAACACATTACATGT ATTTTGTGCAATTAGTGGTACATCAAGTGACCGAGGTTATGGTTCCCCAAGATACGCTGAAGTGTGAGGAAATGCAGATGTACGTGACAA TGAGACTGACCTTTCTCAGGAATATTTGGAGCTGTGCAAATGTTAAAATTTAAAGATTTGATATACATGGAGTGTTTCTTCTCGACACCA AAATTTTCATGTGTTCCAACAGGGTGCTTACATATTTGTAAATAAGCAACTTGAAAGTGCCTGGAAAATTGCACCACTGTGCTTGGTTTG TACTTTTTTAGGTAAATCTATATGCTGAAAAGTAGAGCTCAAAAACAGTAGTTCAATTTGCTTAATTATTGCTTAAAATAATGGTACTAT >53156_53156_2_MEX3D-DOCK11_MEX3D_chr19_1567463_ENST00000388824_DOCK11_chrX_117676688_ENST00000276204_length(amino acids)=2035AA_BP= MDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCK SLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIY LDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERSMH PELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLAL FDVKNNCKISADFHVDLNPPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNITHC AEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQII PGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRD SDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPL LKDGRIITFEQQLPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKY LKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMI AILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLK RCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRE TSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFTSPANR GSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYW NKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFH QALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAF CYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAE VKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNG CSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEV MHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYF DDKELTERKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKL CSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRD -------------------------------------------------------------- >53156_53156_3_MEX3D-DOCK11_MEX3D_chr19_1567463_ENST00000402693_DOCK11_chrX_117676688_ENST00000276202_length(transcript)=7055nt_BP=595nt ATGCCCAGCTCGCTCGGCCAGCCCGACGGCGGCGGGGGCGGGGGCGGCGGCGGCGGCGGCGTGGGGGCGGCGGGGGAGGACCCCGGACCC GGACCTGCGCCCCCGCCCGAGGGCGCCCAGGAGGCCGCGCCCGCGCCCCGGCCGCCGCCCGAACCCGACGACGCGGCCGCCGCGCTCCGC CTGGCGCTGGACCAGCTGTCGGCGCTCGGGCTGGGGGGCGCTGGCGACACGGACGAGGAGGGGGCGGCCGGGGACGGCGCAGCGGCGGCG GGGGGCGCGGACGGCGGGGCGGCTCCGGAGCCTGTGCCCCCCGACGGACCTGAGGCCGGCGCGCCCCCGACCCTGGCCCCCGCCGTGGCC CCCGGGTCGCTGCCGCTGCTGGACCCCAACGCGAGTCCCCCGCCGCCGCCGCCGCCCCGGCCGTCGCCCCCCGACGTGTTCGCGGGCTTC GCGCCCCACCCCGCGGCCCTGGGGCCCCCGACGCTGCTGGCCGACCAGATGAGCGTGATCGGCAGCCGCAAGAAAAGCGTCAACATGACC GAGTGCGTCCCGGTGCCCAGCTCCGAGCACGTCGCCGAGATCGTGGGTCGCCAGGGAAAAGGCCAAAGTTGTTGAGCCCCTGGACTATGA GAATGTTATTGCCCAAAGAAAAACCCAGATTTACAGCGACCCCCTCCGAGATCTGCTTATGTTCCCAATGGAAGATATATCTATCTCGGT GATAGGTCGTCAACGCAGAACGGTGCAGTCTACTGTACCAGAAGATGCTGAAAAGAGGGCCCAGAGTTTATTTGTTAAAGAGTGTATTAA AACCTATAGCACAGATTGGCACGTGGTAAACTACAAGTATGAGGACTTCTCTGGGGACTTTCGAATGTTGCCATGTAAATCTTTGAGACC AGAAAAGATTCCTAATCATGTATTTGAGATAGATGAAGACTGTGAGAAAGATGAGGACTCATCTTCTTTATGTTCTCAGAAGGGTGGTGT GATAAAACAAGGCTGGTTGCATAAAGCAAATGTAAATAGTACCATCACAGTAACCATGAAGGTATTCAAGAGACGATATTTTTACTTGAC CCAACTTCCTGACGGTTCATATATTCTCAATTCCTATAAAGATGAGAAAAATTCAAAAGAATCGAAAGGTTGCATCTACTTGGACGCCTG CATTGATGTTGTTCAGTGCCCCAAAATGCGCCGTCATGCTTTTGAACTCAAGATGTTAGATAAATATAGCCATTATCTGGCTGCTGAAAC TGAGCAGGAAATGGAGGAATGGTTGATAACTTTGAAAAAGATTATTCAGATCAACACCGACAGTTTAGTTCAAGAAAAAAAGGAGACGGT AGAAACAGCACAAGATGATGAAACTAGCAGCCAAGGAAAAGCCGAGAACATCATGGCAAGTTTGGAAAGGAGCATGCATCCGGAACTGAT GAAGTATGGAAGAGAAACTGAACAACTAAACAAACTCAGTAGAGGAGATGGAAGACAGAATCTCTTTTCTTTTGATTCAGAAGTTCAGAG GTTGGACTTTTCAGGAATTGAACCTGATATAAAGCCATTTGAAGAAAAATGCAATAAACGTTTCCTGGTGAATTGCCATGATTTAACTTT CAATATCTTGGGCCAAATTGGAGACAATGCAAAAGGACCACCCACAAATGTTGAGCCCTTTTTTATCAATCTTGCCTTATTTGATGTAAA GAACAATTGTAAGATTTCAGCAGACTTTCATGTAGACCTGAATCCCCCATCTGTCCGTGAAATGCTGTGGGGCTCTTCAACCCAACTGGC CAGTGACGGTAGCCCAAAGGGCTCTTCACCCGAATCTTACATTCATGGAATTGCCGAATCTCAGTTACGCTACATACAACAGGGAATTTT CTCAGTGACGAATCCACATCCTGAAATTTTTCTAGTTGCCAGAATTGAAAAGGTACTACAGGGAAACATTACACACTGTGCAGAACCCTA TATCAAAAATTCTGATCCAGTAAAGACGGCCCAGAAGGTGCACAGGACAGCTAAACAAGTGTGTAGCCGCCTTGGACAATACAGAATGCC CTTCGCTTGGGCTGCCAGACCCATTTTCAAAGATACTCAAGGCTCTCTTGATCTGGATGGGAGATTTTCTCCTCTGTATAAACAAGACAG TAGCAAGCTTTCAAGTGAAGACATTCTCAAGTTGCTCTCAGAATATAAGAAGCCAGAAAAGACCAAACTGCAGATTATTCCTGGGCAGCT AAACATCACAGTAGAATGTGTTCCTGTGGATTTATCAAATTGTATTACTTCTTCATATGTGCCCTTGAAGCCTTTTGAAAAGAATTGCCA AAATATTACTGTGGAGGTTGAAGAGTTTGTTCCAGAAATGACAAAATATTGTTATCCATTTACTATTTACAAAAACCATCTGTATGTATA TCCCCTGCAATTAAAATACGATAGCCAGAAAACATTTGCCAAGGCAAGGAACATTGCAGTCTGTGTGGAATTCCGGGATTCAGATGAAAG TGACGCTAGTGCCCTAAAGTGTATTTATGGAAAACCTGCAGGGTCTGTTTTTACCACAAATGCTTATGCTGTTGTCTCGCATCACAACCA AAATCCAGAGTTCTATGATGAGATTAAAATTGAGCTTCCCATTCACCTACATCAAAAACATCATTTGCTTTTCACTTTTTATCATGTAAG TTGTGAAATTAACACAAAGGGAACAACCAAAAAGCAAGACACAGTTGAAACTCCAGTTGGGTTTGCCTGGGTACCTTTGCTGAAAGATGG TAGAATCATCACATTTGAGCAGCAGCTGCCAGTTTCCGCCAATCTTCCCCCAGGCTACTTGAATCTGAATGATGCAGAATCAAGAAGGCA ATGTAACGTGGATATTAAATGGGTAGATGGTGCAAAGCCTTTGTTGAAGATTAAAAGCCACTTAGAATCTACCATTTACACTCAAGATCT GCATGTGCACAAATTCTTCCATCATTGCCAGCTGATTCAGTCAGGCTCGAAAGAAGTTCCAGGGGAGCTCATTAAATATTTAAAGTGTTT GCATGCCATGGAGATCCAAGTCATGATACAGTTTCTACCTGTAATTCTTATGCAACTCTTCCGAGTTCTCACAAATATGACCCATGAAGA TGACGTTCCTATCAACTGCACCATGGTTCTCTTACATATTGTATCAAAGTGCCATGAAGAAGGCTTGGATAGTTATCTAAGATCATTCAT AAAGTATAGCTTCCGACCTGAAAAACCGAGTGCTCCTCAGGCCCAGCTGATACATGAAACCCTGGCTACTACGATGATAGCAATATTGAA ACAGTCTGCAGATTTTTTATCAATAAACAAATTGCTAAAGTACTCATGGTTTTTCTTTGAAATAATTGCAAAGTCAATGGCCACATACTT GTTGGAAGAGAATAAGATTAAGCTTCCCCGAGGCCAGAGATTTCCCGAGACATATCATCATGTCTTACATTCACTGCTTCTTGCAATAAT TCCCCATGTGACTATTCGGTATGCGGAGATTCCCGATGAGTCCAGAAATGTGAACTATAGTTTGGCTAGCTTCCTGAAGCGCTGTTTGAC ACTAATGGATAGAGGATTTATTTTCAATTTAATAAATGACTATATATCTGGATTCAGCCCCAAAGATCCTAAGGTTCTGGCTGAATACAA GTTTGAATTTCTGCAAACAATTTGCAATCACGAACATTACATTCCTCTGAACTTGCCAATGGCATTTGCAAAACCTAAACTGCAGCGGGT TCAAGATTCAAATCTTGAATACAGTTTATCAGATGAGTATTGCAAGCATCACTTCTTGGTTGGTCTACTTCTGAGGGAAACTTCCATTGC TCTTCAGGACAATTATGAGATCAGATATACAGCTATCTCTGTTATAAAGAATCTTTTGATAAAACATGCATTTGACACAAGATACCAGCA CAAGAACCAACAAGCCAAAATAGCACAATTGTACCTCCCCTTTGTTGGACTACTTTTGGAAAATATACAGCGATTAGCAGGTCGAGATAC CTTGTATTCTTGTGCAGCCATGCCTAATTCTGCATCCAGAGATGAGTTTCCATGTGGCTTTACTTCACCTGCCAATAGAGGGAGTCTGAG CACTGACAAAGACACCGCTTATGGGTCTTTTCAAAATGGACATGGAATTAAGAGAGAAGATTCAAGAGGTTCCCTCATCCCAGAAGGAGC AACAGGATTTCCAGATCAGGGCAACACTGGTGAAAATACCCGACAGAGTTCTACAAGGAGTAGTGTATCCCAGTATAACCGCCTGGATCA GTATGAAATCAGAAGCCTCCTGATGTGCTACCTGTATATAGTAAAAATGATTTCAGAAGATACTCTCTTAACTTACTGGAATAAAGTATC ACCTCAGGAGCTCATAAACATTCTTATACTTTTAGAAGTATGCTTGTTTCACTTTAGATATATGGGGAAAAGAAACATAGCAAGGGTGCA TGATGCCTGGCTGTCAAAACACTTCGGAATAGACCGAAAATCGCAAACCATGCCTGCTCTTCGAAACAGATCAGGAGTAATGCAGGCCCG GCTTCAGCATCTTAGTAGCCTAGAAAGTTCATTTACACTTAATCACAGTTCTACAACAACTGAAGCAGACATTTTCCACCAGGCACTTCT TGAAGGCAATACAGCTACTGAAGTTTCCCTAACAGTACTAGACACCATATCATTTTTCACTCAGTGCTTCAAGACCCAACTTTTAAATAA TGATGGCCATAACCCATTAATGAAAAAAGTGTTTGATATACATCTTGCTTTTCTTAAAAATGGACAATCTGAAGTGTCGCTGAAACATGT ATTTGCCTCACTGAGAGCTTTCATCAGTAAGTTTCCTTCAGCATTTTTCAAAGGAAGAGTAAACATGTGTGCTGCATTTTGCTATGAGGT TTTAAAGTGCTGCACATCGAAGATTAGCTCAACCAGGAATGAAGCATCTGCACTTTTGTATCTTTTGATGAGAAACAACTTTGAGTATAC CAAAAGGAAAACCTTTTTGAGGACACATCTACAGATAATAATTGCTGTAAGCCAACTGATAGCTGATGTAGCACTAAGCGGAGGATCAAG ATTTCAGGAGTCTTTATTCATTATCAATAATTTTGCAAATAGTGACAGACCTATGAAGGCAACTGCCTTTCCCGCAGAAGTCAAAGACTT GACCAAGAGAATCCGCACTGTTCTTATGGCCACTGCCCAAATGAAGGAGCATGAGAAAGACCCTGAAATGCTAATTGATCTCCAGTATAG CTTAGCCAAGTCCTATGCAAGCACCCCAGAGCTCAGGAAAACCTGGCTTGATAGCATGGCCAAGATTCATGTAAAAAATGGAGATTTTTC AGAGGCTGCGATGTGTTATGTCCATGTAGCAGCTCTAGTTGCAGAGTTTCTTCATCGAAAAAAATTATTTCCTAACGGATGTTCAGCGTT CAAGAAAATTACTCCCAATATAGATGAAGAAGGAGCAATGAAAGAAGATGCTGGGATGATGGATGTCCATTATAGTGAAGAGGTCTTGCT GGAGTTGCTAGAACAATGTGTGGATGGCTTATGGAAGGCAGAACGTTATGAAATAATTTCTGAGATTTCCAAGTTGATCGTTCCAATTTA TGAGAAACGTCGTGAGTTTGAGAAACTTACTCAAGTTTATAGAACTCTTCATGGAGCTTACACAAAAATTCTGGAAGTTATGCATACAAA AAAGAGACTTTTAGGCACTTTCTTCAGAGTTGCCTTTTATGGCCAATCTTTTTTTGAAGAAGAAGATGGAAAGGAGTACATCTATAAAGA ACCAAAGCTCACTGGCCTCTCAGAAATTTCCTTGAGACTTGTTAAACTTTATGGTGAAAAGTTTGGTACGGAGAATGTCAAAATAATTCA GGATTCAGACAAGGTAAATGCCAAAGAGCTTGATCCAAAATATGCTCATATACAAGTTACTTATGTGAAGCCTTACTTTGATGACAAAGA ACTCACAGAAAGGAAGACCGAGTTTGAAAGAAATCATAATATCAGCAGATTTGTTTTTGAGGCCCCTTACACTTTATCAGGCAAAAAACA GGGCTGTATAGAAGAACAGTGCAAACGCCGTACAATCTTGACAACTTCAAACTCGTTTCCTTACGTGAAGAAGAGGATTCCTATTAACTG TGAACAGCAGATTAATTTAAAACCAATTGATGTTGCCACTGATGAAATAAAAGATAAAACTGCAGAGCTGCAAAAGCTTTGCTCCTCTAC TGACGTGGACATGATTCAGCTCCAACTTAAATTGCAGGGCTGTGTTTCTGTGCAGGTCAATGCTGGTCCATTAGCATATGCAAGAGCTTT CTTAAATGACAGCCAAGCTAGCAAGTATCCACCTAAGAAAGTGAGTGAGTTGAAAGACATGTTTAGGAAATTTATACAAGCATGCAGCAT TGCACTTGAACTAAATGAGCGGCTAATTAAAGAAGATCAAGTTGAGTACCATGAAGGGCTAAAGTCAAATTTCAGAGACATGGTAAAAGA ATTATCTGACATTATCCATGAGCAGATATTACAAGAAGACACAATGCATTCTCCCTGGATGAGCAACACATTACATGTATTTTGTGCAAT TAGTGGTACATCAAGTGACCGAGGTTATGGTTCCCCAAGATACGCTGAAGTGTGAGGAAATGCAGATGTACGTGACAATGAGACTGACCT TTCTCAGGAATATTTGGAGCTGTGCAAATGTTAAAATTTAAAGATTTGATATACATGGAGTGTTTCTTCTCGACACCAAAATTTTCATGT GTTCCAACAGGGTGCTTACATATTTGTAAATAAGCAACTTGAAAGTGCCTGGAAAATTGCACCACTGTGCTTGGTTTGTACTTTTTTAGG TAAATCTATATGCTGAAAAGTAGAGCTCAAAAACAGTAGTTCAATTTGCTTAATTATTGCTTAAAATAATGGTACTATGTAAAATTGTAT >53156_53156_3_MEX3D-DOCK11_MEX3D_chr19_1567463_ENST00000402693_DOCK11_chrX_117676688_ENST00000276202_length(amino acids)=2031AA_BP= MDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCK SLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIY LDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERSMH PELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLAL FDVKNNCKISADFHVDLNPPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNITHC AEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQII PGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRD SDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPL LKDGRIITFEQQLPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKY LKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMI AILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLK RCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRE TSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFTSPANR GSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYW NKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFH QALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAF CYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAE VKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNG CSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEV MHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYF DDKELTERKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKL CSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRD -------------------------------------------------------------- >53156_53156_4_MEX3D-DOCK11_MEX3D_chr19_1567463_ENST00000402693_DOCK11_chrX_117676688_ENST00000276204_length(transcript)=7083nt_BP=595nt ATGCCCAGCTCGCTCGGCCAGCCCGACGGCGGCGGGGGCGGGGGCGGCGGCGGCGGCGGCGTGGGGGCGGCGGGGGAGGACCCCGGACCC GGACCTGCGCCCCCGCCCGAGGGCGCCCAGGAGGCCGCGCCCGCGCCCCGGCCGCCGCCCGAACCCGACGACGCGGCCGCCGCGCTCCGC CTGGCGCTGGACCAGCTGTCGGCGCTCGGGCTGGGGGGCGCTGGCGACACGGACGAGGAGGGGGCGGCCGGGGACGGCGCAGCGGCGGCG GGGGGCGCGGACGGCGGGGCGGCTCCGGAGCCTGTGCCCCCCGACGGACCTGAGGCCGGCGCGCCCCCGACCCTGGCCCCCGCCGTGGCC CCCGGGTCGCTGCCGCTGCTGGACCCCAACGCGAGTCCCCCGCCGCCGCCGCCGCCCCGGCCGTCGCCCCCCGACGTGTTCGCGGGCTTC GCGCCCCACCCCGCGGCCCTGGGGCCCCCGACGCTGCTGGCCGACCAGATGAGCGTGATCGGCAGCCGCAAGAAAAGCGTCAACATGACC GAGTGCGTCCCGGTGCCCAGCTCCGAGCACGTCGCCGAGATCGTGGGTCGCCAGGGAAAAGGCCAAAGTTGTTGAGCCCCTGGACTATGA GAATGTTATTGCCCAAAGAAAAACCCAGATTTACAGCGACCCCCTCCGAGATCTGCTTATGTTCCCAATGGAAGATATATCTATCTCGGT GATAGGTCGTCAACGCAGAACGGTGCAGTCTACTGTACCAGAAGATGCTGAAAAGAGGGCCCAGAGTTTATTTGTTAAAGAGTGTATTAA AACCTATAGCACAGATTGGCACGTGGTAAACTACAAGTATGAGGACTTCTCTGGGGACTTTCGAATGTTGCCATGTAAATCTTTGAGACC AGAAAAGATTCCTAATCATGTATTTGAGATAGATGAAGACTGTGAGAAAGATGAGGACTCATCTTCTTTATGTTCTCAGAAGGGTGGTGT GATAAAACAAGGCTGGTTGCATAAAGCAAATGTAAATAGTACCATCACAGTAACCATGAAGGTATTCAAGAGACGATATTTTTACTTGAC CCAACTTCCTGACGGTTCATATATTCTCAATTCCTATAAAGATGAGAAAAATTCAAAAGAATCGAAAGGTTGCATCTACTTGGACGCCTG CATTGATGTTGTTCAGTGCCCCAAAATGCGCCGTCATGCTTTTGAACTCAAGATGTTAGATAAATATAGCCATTATCTGGCTGCTGAAAC TGAGCAGGAAATGGAGGAATGGTTGATAACTTTGAAAAAGATTATTCAGATCAACACCGACAGTTTAGTTCAAGAAAAAAAGGAGACGGT AGAAACAGCACAAGATGATGAAACTAGCAGCCAAGGAAAAGCCGAGAACATCATGGCAAGTTTGGAAAGGAGCATGCATCCGGAACTGAT GAAGTATGGAAGAGAAACTGAACAACTAAACAAACTCAGTAGAGGAGATGGAAGACAGAATCTCTTTTCTTTTGATTCAGAAGTTCAGAG GTTGGACTTTTCAGGAATTGAACCTGATATAAAGCCATTTGAAGAAAAATGCAATAAACGTTTCCTGGTGAATTGCCATGATTTAACTTT CAATATCTTGGGCCAAATTGGAGACAATGCAAAAGGACCACCCACAAATGTTGAGCCCTTTTTTATCAATCTTGCCTTATTTGATGTAAA GAACAATTGTAAGATTTCAGCAGACTTTCATGTAGACCTGAATCCCCCATCTGTCCGTGAAATGCTGTGGGGCTCTTCAACCCAACTGGC CAGTGACGGTAGCCCAAAGGGCTCTTCACCCGAATCTTACATTCATGGAATTGCCGAATCTCAGTTACGCTACATACAACAGGGAATTTT CTCAGTGACGAATCCACATCCTGAAATTTTTCTAGTTGCCAGAATTGAAAAGGTACTACAGGGAAACATTACACACTGTGCAGAACCCTA TATCAAAAATTCTGATCCAGTAAAGACGGCCCAGAAGGTGCACAGGACAGCTAAACAAGTGTGTAGCCGCCTTGGACAATACAGAATGCC CTTCGCTTGGGCTGCCAGACCCATTTTCAAAGATACTCAAGGCTCTCTTGATCTGGATGGGAGATTTTCTCCTCTGTATAAACAAGACAG TAGCAAGCTTTCAAGTGAAGACATTCTCAAGTTGCTCTCAGAATATAAGAAGCCAGAAAAGACCAAACTGCAGATTATTCCTGGGCAGCT AAACATCACAGTAGAATGTGTTCCTGTGGATTTATCAAATTGTATTACTTCTTCATATGTGCCCTTGAAGCCTTTTGAAAAGAATTGCCA AAATATTACTGTGGAGGTTGAAGAGTTTGTTCCAGAAATGACAAAATATTGTTATCCATTTACTATTTACAAAAACCATCTGTATGTATA TCCCCTGCAATTAAAATACGATAGCCAGAAAACATTTGCCAAGGCAAGGAACATTGCAGTCTGTGTGGAATTCCGGGATTCAGATGAAAG TGACGCTAGTGCCCTAAAGTGTATTTATGGAAAACCTGCAGGGTCTGTTTTTACCACAAATGCTTATGCTGTTGTCTCGCATCACAACCA AAATCCAGAGTTCTATGATGAGATTAAAATTGAGCTTCCCATTCACCTACATCAAAAACATCATTTGCTTTTCACTTTTTATCATGTAAG TTGTGAAATTAACACAAAGGGAACAACCAAAAAGCAAGACACAGTTGAAACTCCAGTTGGGTTTGCCTGGGTACCTTTGCTGAAAGATGG TAGAATCATCACATTTGAGCAGCAGCTGCCAGTTTCCGCCAATCTTCCCCCAGGCTACTTGAATCTGAATGATGCAGAATCAAGAAGGCA ATGTAACGTGGATATTAAATGGGTAGATGGTGCAAAGCCTTTGTTGAAGATTAAAAGCCACTTAGAATCTACCATTTACACTCAAGATCT GCATGTGCACAAATTCTTCCATCATTGCCAGCTGATTCAGTCAGGCTCGAAAGAAGTTCCAGGGGAGCTCATTAAATATTTAAAGTGTTT GCATGCCATGGAGATCCAAGTCATGATACAGTTTCTACCTGTAATTCTTATGCAACTCTTCCGAGTTCTCACAAATATGACCCATGAAGA TGACGTTCCTATCAACTGCACCATGGTTCTCTTACATATTGTATCAAAGTGCCATGAAGAAGGCTTGGATAGTTATCTAAGATCATTCAT AAAGTATAGCTTCCGACCTGAAAAACCGAGTGCTCCTCAGGCCCAGCTGATACATGAAACCCTGGCTACTACGATGATAGCAATATTGAA ACAGTCTGCAGATTTTTTATCAATAAACAAATTGCTAAAGTACTCATGGTTTTTCTTTGAAATAATTGCAAAGTCAATGGCCACATACTT GTTGGAAGAGAATAAGATTAAGCTTCCCCGAGGCCAGAGATTTCCCGAGACATATCATCATGTCTTACATTCACTGCTTCTTGCAATAAT TCCCCATGTGACTATTCGGTATGCGGAGATTCCCGATGAGTCCAGAAATGTGAACTATAGTTTGGCTAGCTTCCTGAAGCGCTGTTTGAC ACTAATGGATAGAGGATTTATTTTCAATTTAATAAATGACTATATATCTGGATTCAGCCCCAAAGATCCTAAGGTTCTGGCTGAATACAA GTTTGAATTTCTGCAAACAATTTGCAATCACGAACATTACATTCCTCTGAACTTGCCAATGGCATTTGCAAAACCTAAACTGCAGCGGGT TCAAGATTCAAATCTTGAATACAGTTTATCAGATGAGTATTGCAAGCATCACTTCTTGGTTGGTCTACTTCTGAGGGAAACTTCCATTGC TCTTCAGGACAATTATGAGATCAGATATACAGCTATCTCTGTTATAAAGAATCTTTTGATAAAACATGCATTTGACACAAGATACCAGCA CAAGAACCAACAAGCCAAAATAGCACAATTGTACCTCCCCTTTGTTGGACTACTTTTGGAAAATATACAGCGATTAGCAGGTCGAGATAC CTTGTATTCTTGTGCAGCCATGCCTAATTCTGCATCCAGAGATGAGTTTCCATGTGGCTTTACTTCACCTGCCAATAGAGGGAGTCTGAG CACTGACAAAGACACCGCTTATGGGTCTTTTCAAAATGGACATGGAATTAAGAGAGAAGATTCAAGAGGTTCCCTCATCCCAGAAGGAGC AACAGGATTTCCAGATCAGGGCAACACTGGTGAAAATACCCGACAGAGTTCTACAAGGAGTAGTGTATCCCAGTATAACCGCCTGGATCA GTATGAAATCAGAAGCCTCCTGATGTGCTACCTGTATATAGTAAAAATGATTTCAGAAGATACTCTCTTAACTTACTGGAATAAAGTATC ACCTCAGGAGCTCATAAACATTCTTATACTTTTAGAAGTATGCTTGTTTCACTTTAGATATATGGGGAAAAGAAACATAGCAAGGGTGCA TGATGCCTGGCTGTCAAAACACTTCGGAATAGACCGAAAATCGCAAACCATGCCTGCTCTTCGAAACAGATCAGGAGTAATGCAGGCCCG GCTTCAGCATCTTAGTAGCCTAGAAAGTTCATTTACACTTAATCACAGTTCTACAACAACTGAAGCAGACATTTTCCACCAGGCACTTCT TGAAGGCAATACAGCTACTGAAGTTTCCCTAACAGTACTAGACACCATATCATTTTTCACTCAGTGCTTCAAGACCCAACTTTTAAATAA TGATGGCCATAACCCATTAATGAAAAAAGTGTTTGATATACATCTTGCTTTTCTTAAAAATGGACAATCTGAAGTGTCGCTGAAACATGT ATTTGCCTCACTGAGAGCTTTCATCAGTAAGTTTCCTTCAGCATTTTTCAAAGGAAGAGTAAACATGTGTGCTGCATTTTGCTATGAGGT TTTAAAGTGCTGCACATCGAAGATTAGCTCAACCAGGAATGAAGCATCTGCACTTTTGTATCTTTTGATGAGAAACAACTTTGAGTATAC CAAAAGGAAAACCTTTTTGAGGACACATCTACAGATAATAATTGCTGTAAGCCAACTGATAGCTGATGTAGCACTAAGCGGAGGATCAAG ATTTCAGGAGTCTTTATTCATTATCAATAATTTTGCAAATAGTGACAGACCTATGAAGGCAACTGCCTTTCCCGCAGAAGTCAAAGACTT GACCAAGAGAATCCGCACTGTTCTTATGGCCACTGCCCAAATGAAGGAGCATGAGAAAGACCCTGAAATGCTAATTGATCTCCAGTATAG CTTAGCCAAGTCCTATGCAAGCACCCCAGAGCTCAGGAAAACCTGGCTTGATAGCATGGCCAAGATTCATGTAAAAAATGGAGATTTTTC AGAGGCTGCGATGTGTTATGTCCATGTAGCAGCTCTAGTTGCAGAGTTTCTTCATCGAAAAAAATTATTTCCTAACGGATGTTCAGCGTT CAAGAAAATTACTCCCAATATAGATGAAGAAGGAGCAATGAAAGAAGATGCTGGGATGATGGATGTCCATTATAGTGAAGAGGTCTTGCT GGAGTTGCTAGAACAATGTGTGGATGGCTTATGGAAGGCAGAACGTTATGAAATAATTTCTGAGATTTCCAAGTTGATCGTTCCAATTTA TGAGAAACGTCGTGAGTTTGAGAAACTTACTCAAGTTTATAGAACTCTTCATGGAGCTTACACAAAAATTCTGGAAGTTATGCATACAAA AAAGAGACTTTTAGGCACTTTCTTCAGAGTTGCCTTTTATGGCCAATCTTTTTTTGAAGAAGAAGATGGAAAGGAGTACATCTATAAAGA ACCAAAGCTCACTGGCCTCTCAGAAATTTCCTTGAGACTTGTTAAACTTTATGGTGAAAAGTTTGGTACGGAGAATGTCAAAATAATTCA GGATTCAGACAAGGTAAATGCCAAAGAGCTTGATCCAAAATATGCTCATATACAAGTTACTTATGTGAAGCCTTACTTTGATGACAAAGA ACTCACAGAAAGGAAGACCGAGTTTGAAAGAAATCATAATATCAGCAGATTTGTTTTTGAGGCCCCTTACACTTTATCAGGCAAAAAACA GGGCTGTATAGAAGAACAGTGCAAACGCCGTACAATCTTGACAACTTCAAACTCGTTTCCTTACGTGAAGAAGAGGATTCCTATTAACTG TGAACAGCAGATTAATTTAAAACCAATTGATGTTGCCACTGATGAAATAAAAGATAAAACTGCAGAGCTGCAAAAGCTTTGCTCCTCTAC TGACGTGGACATGATTCAGCTCCAACTTAAATTGCAGGGCTGTGTTTCTGTGCAGGTCAATGCTGGTCCATTAGCATATGCAAGAGCTTT CTTAAATGACAGCCAAGCTAGCAAGTATCCACCTAAGAAAGTGAGTGAGTTGAAAGACATGTTTAGGAAATTTATACAAGCATGCAGCAT TGCACTTGAACTAAATGAGCGGCTAATTAAAGAAGATCAAGTTGAGTACCATGAAGGGCTAAAGTCAAATTTCAGAGACATGGTAAAAGA ATTATCTGACATTATCCATGAGCAGGCAAGTATTAGGATATTACAAGAAGACACAATGCATTCTCCCTGGATGAGCAACACATTACATGT ATTTTGTGCAATTAGTGGTACATCAAGTGACCGAGGTTATGGTTCCCCAAGATACGCTGAAGTGTGAGGAAATGCAGATGTACGTGACAA TGAGACTGACCTTTCTCAGGAATATTTGGAGCTGTGCAAATGTTAAAATTTAAAGATTTGATATACATGGAGTGTTTCTTCTCGACACCA AAATTTTCATGTGTTCCAACAGGGTGCTTACATATTTGTAAATAAGCAACTTGAAAGTGCCTGGAAAATTGCACCACTGTGCTTGGTTTG TACTTTTTTAGGTAAATCTATATGCTGAAAAGTAGAGCTCAAAAACAGTAGTTCAATTTGCTTAATTATTGCTTAAAATAATGGTACTAT >53156_53156_4_MEX3D-DOCK11_MEX3D_chr19_1567463_ENST00000402693_DOCK11_chrX_117676688_ENST00000276204_length(amino acids)=2035AA_BP= MDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCK SLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIY LDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERSMH PELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLAL FDVKNNCKISADFHVDLNPPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNITHC AEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQII PGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRD SDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPL LKDGRIITFEQQLPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKY LKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMI AILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLK RCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRE TSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFTSPANR GSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYW NKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFH QALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAF CYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAE VKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNG CSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEV MHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYF DDKELTERKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKL CSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRD -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for MEX3D-DOCK11 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for MEX3D-DOCK11 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for MEX3D-DOCK11 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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