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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MFGE8-IGF1R (FusionGDB2 ID:53178)

Fusion Gene Summary for MFGE8-IGF1R

check button Fusion gene summary
Fusion gene informationFusion gene name: MFGE8-IGF1R
Fusion gene ID: 53178
HgeneTgene
Gene symbol

MFGE8

IGF1R

Gene ID

4240

3480

Gene namemilk fat globule EGF and factor V/VIII domain containinginsulin like growth factor 1 receptor
SynonymsBA46|EDIL1|HMFG|HsT19888|MFG-E8|MFGM|OAcGD3S|SED1|SPAG10|hP47CD221|IGFIR|IGFR|JTK13
Cytomap

15q26.1

15q26.3

Type of geneprotein-codingprotein-coding
DescriptionlactadherinO-acetyl disialoganglioside synthasebreast epithelial antigen BA46medinmilk fat globule-EGF factor 8 proteinsperm associated antigen 10sperm surface protein hP47insulin-like growth factor 1 receptorIGF-I receptorsoluble IGF1R variant 1soluble IGF1R variant 2
Modification date2020032220200329
UniProtAcc.

P08069

Ensembl transtripts involved in fusion geneENST00000268150, ENST00000268151, 
ENST00000539437, ENST00000542878, 
ENST00000566497, ENST00000559997, 
ENST00000560432, ENST00000268035, 
ENST00000558762, 
Fusion gene scores* DoF score6 X 5 X 4=12014 X 14 X 5=980
# samples 616
** MAII scorelog2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/980*10)=-2.61470984411521
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MFGE8 [Title/Abstract] AND IGF1R [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMFGE8(89448988)-IGF1R(99434554), # samples:2
Anticipated loss of major functional domain due to fusion event.MFGE8-IGF1R seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
MFGE8-IGF1R seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneIGF1R

GO:0043066

negative regulation of apoptotic process

12556535

TgeneIGF1R

GO:0046328

regulation of JNK cascade

12556535

TgeneIGF1R

GO:0046777

protein autophosphorylation

1846292|7679099|11162456

TgeneIGF1R

GO:0048009

insulin-like growth factor receptor signaling pathway

7679099

TgeneIGF1R

GO:0048015

phosphatidylinositol-mediated signaling

7692086

TgeneIGF1R

GO:0051389

inactivation of MAPKK activity

12556535


check buttonFusion gene breakpoints across MFGE8 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across IGF1R (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E9-A1NF-01AMFGE8chr15

89448988

-IGF1Rchr15

99434554

+


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Fusion Gene ORF analysis for MFGE8-IGF1R

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000268150ENST00000560432MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
5CDS-3UTRENST00000268151ENST00000560432MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
5CDS-3UTRENST00000539437ENST00000560432MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
5CDS-3UTRENST00000542878ENST00000560432MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
5CDS-3UTRENST00000566497ENST00000560432MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
Frame-shiftENST00000539437ENST00000268035MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
Frame-shiftENST00000539437ENST00000558762MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
Frame-shiftENST00000566497ENST00000268035MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
Frame-shiftENST00000566497ENST00000558762MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
In-frameENST00000268150ENST00000268035MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
In-frameENST00000268150ENST00000558762MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
In-frameENST00000268151ENST00000268035MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
In-frameENST00000268151ENST00000558762MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
In-frameENST00000542878ENST00000268035MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
In-frameENST00000542878ENST00000558762MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
intron-3CDSENST00000559997ENST00000268035MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
intron-3CDSENST00000559997ENST00000558762MFGE8chr15

89448988

-IGF1Rchr15

99434554

+
intron-3UTRENST00000559997ENST00000560432MFGE8chr15

89448988

-IGF1Rchr15

99434554

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000268151MFGE8chr1589448988-ENST00000268035IGF1Rchr1599434554+112997471742101397
ENST00000268151MFGE8chr1589448988-ENST00000558762IGF1Rchr1599434554+112957471742071396
ENST00000268150MFGE8chr1589448988-ENST00000268035IGF1Rchr1599434554+113297774742401397
ENST00000268150MFGE8chr1589448988-ENST00000558762IGF1Rchr1599434554+113257774742371396
ENST00000542878MFGE8chr1589448988-ENST00000268035IGF1Rchr1599434554+111656131540761353
ENST00000542878MFGE8chr1589448988-ENST00000558762IGF1Rchr1599434554+111616131540731352

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000268151ENST00000268035MFGE8chr1589448988-IGF1Rchr1599434554+0.0001581210.9998418
ENST00000268151ENST00000558762MFGE8chr1589448988-IGF1Rchr1599434554+0.0003879330.99961215
ENST00000268150ENST00000268035MFGE8chr1589448988-IGF1Rchr1599434554+0.0001616850.99983823
ENST00000268150ENST00000558762MFGE8chr1589448988-IGF1Rchr1599434554+0.0003969230.9996031
ENST00000542878ENST00000268035MFGE8chr1589448988-IGF1Rchr1599434554+0.0001666710.99983335
ENST00000542878ENST00000558762MFGE8chr1589448988-IGF1Rchr1599434554+0.0004080830.9995919

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Fusion Genomic Features for MFGE8-IGF1R


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MFGE8-IGF1R


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:89448988/chr15:99434554)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.IGF1R

P08069

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand binding activates the receptor kinase, leading to receptor autophosphorylation, and tyrosines phosphorylation of multiple substrates, that function as signaling adapter proteins including, the insulin-receptor substrates (IRS1/2), Shc and 14-3-3 proteins. Phosphorylation of IRSs proteins lead to the activation of two main signaling pathways: the PI3K-AKT/PKB pathway and the Ras-MAPK pathway. The result of activating the MAPK pathway is increased cellular proliferation, whereas activating the PI3K pathway inhibits apoptosis and stimulates protein synthesis. Phosphorylated IRS1 can activate the 85 kDa regulatory subunit of PI3K (PIK3R1), leading to activation of several downstream substrates, including protein AKT/PKB. AKT phosphorylation, in turn, enhances protein synthesis through mTOR activation and triggers the antiapoptotic effects of IGFIR through phosphorylation and inactivation of BAD. In parallel to PI3K-driven signaling, recruitment of Grb2/SOS by phosphorylated IRS1 or Shc leads to recruitment of Ras and activation of the ras-MAPK pathway. In addition to these two main signaling pathways IGF1R signals also through the Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT). Phosphorylation of JAK proteins can lead to phosphorylation/activation of signal transducers and activators of transcription (STAT) proteins. In particular activation of STAT3, may be essential for the transforming activity of IGF1R. The JAK/STAT pathway activates gene transcription and may be responsible for the transforming activity. JNK kinases can also be activated by the IGF1R. IGF1 exerts inhibiting activities on JNK activation via phosphorylation and inhibition of MAP3K5/ASK1, which is able to directly associate with the IGF1R.; FUNCTION: When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMFGE8chr15:89448988chr15:99434554ENST00000268150-5824_67228388.0DomainEGF-like
HgeneMFGE8chr15:89448988chr15:99434554ENST00000566497-5924_67228499.3333333333333DomainEGF-like
HgeneMFGE8chr15:89448988chr15:99434554ENST00000268150-5846_48228388.0MotifNote=Cell attachment site
HgeneMFGE8chr15:89448988chr15:99434554ENST00000566497-5946_48228499.3333333333333MotifNote=Cell attachment site
TgeneIGF1Rchr15:89448988chr15:99434554ENST00000268035121491_6092131368.0DomainFibronectin type-III 1
TgeneIGF1Rchr15:89448988chr15:99434554ENST00000268035121610_7082131368.0DomainFibronectin type-III 2
TgeneIGF1Rchr15:89448988chr15:99434554ENST00000268035121735_8282131368.0DomainFibronectin type-III 3
TgeneIGF1Rchr15:89448988chr15:99434554ENST00000268035121834_9272131368.0DomainFibronectin type-III 4
TgeneIGF1Rchr15:89448988chr15:99434554ENST00000268035121999_12742131368.0DomainProtein kinase
TgeneIGF1Rchr15:89448988chr15:99434554ENST00000268035121977_9802131368.0MotifNote=IRS1- and SHC1-binding
TgeneIGF1Rchr15:89448988chr15:99434554ENST000002680351211005_10132131368.0Nucleotide bindingATP
TgeneIGF1Rchr15:89448988chr15:99434554ENST00000268035121741_9352131368.0Topological domainExtracellular
TgeneIGF1Rchr15:89448988chr15:99434554ENST00000268035121960_13672131368.0Topological domainCytoplasmic
TgeneIGF1Rchr15:89448988chr15:99434554ENST00000268035121936_9592131368.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for MFGE8-IGF1R


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>53178_53178_1_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000268150_IGF1R_chr15_99434554_ENST00000268035_length(transcript)=11329nt_BP=777nt
TGATTTATTCCGGTCCCAGAGGAGAAGGCGCCAGAACCCCGCGGGGTCTGAGCAGCCCAGCGTGCCCATTCCAGCGCCCGCGTCCCCGCA
GCATGCCGCGCCCCCGCCTGCTGGCCGCGCTGTGCGGCGCGCTGCTCTGCGCCCCCAGCCTCCTCGTCGCCCTGGATATCTGTTCCAAAA
ACCCCTGCCACAACGGTGGTTTATGCGAGGAGATTTCCCAAGAAGTGCGAGGAGATGTCTTCCCCTCGTACACCTGCACGTGCCTTAAGG
GCTACGCGGGCAACCACTGTGAGACGAAATGTGTCGAGCCACTGGGCCTGGAGAATGGGAACATTGCCAACTCACAGATCGCCGCCTCGT
CTGTGCGTGTGACCTTCTTGGGTTTGCAGCATTGGGTCCCGGAGCTGGCCCGCCTGAACCGCGCAGGCATGGTCAATGCCTGGACACCCA
GCAGCAATGACGATAACCCCTGGATCCAGGTGAACCTGCTGCGGAGGATGTGGGTAACAGGTGTGGTGACGCAGGGTGCCAGCCGCTTGG
CCAGTCATGAGTACCTGAAGGCCTTCAAGGTGGCCTACAGCCTTAATGGACACGAATTCGATTTCATCCATGATGTTAATAAAAAACACA
AGGAGTTTGTGGGTAACTGGAACAAAAACGCGGTGCATGTCAACCTGTTTGAGACCCCTGTGGAGGCTCAGTACGTGAGATTGTACCCCA
CGAGCTGCCACACGGCCTGCACTCTGCGCTTTGAGCTACTGGGCTGTGAGCTGAACGTGTGCCCAAGCACGTGTGGGAAGCGGGCGTGCA
CCGAGAACAATGAGTGCTGCCACCCCGAGTGCCTGGGCAGCTGCAGCGCGCCTGACAACGACACGGCCTGTGTAGCTTGCCGCCACTACT
ACTATGCCGGTGTCTGTGTGCCTGCCTGCCCGCCCAACACCTACAGGTTTGAGGGCTGGCGCTGTGTGGACCGTGACTTCTGCGCCAACA
TCCTCAGCGCCGAGAGCAGCGACTCCGAGGGGTTTGTGATCCACGACGGCGAGTGCATGCAGGAGTGCCCCTCGGGCTTCATCCGCAACG
GCAGCCAGAGCATGTACTGCATCCCTTGTGAAGGTCCTTGCCCGAAGGTCTGTGAGGAAGAAAAGAAAACAAAGACCATTGATTCTGTTA
CTTCTGCTCAGATGCTCCAAGGATGCACCATCTTCAAGGGCAATTTGCTCATTAACATCCGACGGGGGAATAACATTGCTTCAGAGCTGG
AGAACTTCATGGGGCTCATCGAGGTGGTGACGGGCTACGTGAAGATCCGCCATTCTCATGCCTTGGTCTCCTTGTCCTTCCTAAAAAACC
TTCGCCTCATCCTAGGAGAGGAGCAGCTAGAAGGGAATTACTCCTTCTACGTCCTCGACAACCAGAACTTGCAGCAACTGTGGGACTGGG
ACCACCGCAACCTGACCATCAAAGCAGGGAAAATGTACTTTGCTTTCAATCCCAAATTATGTGTTTCCGAAATTTACCGCATGGAGGAAG
TGACGGGGACTAAAGGGCGCCAAAGCAAAGGGGACATAAACACCAGGAACAACGGGGAGAGAGCCTCCTGTGAAAGTGACGTCCTGCATT
TCACCTCCACCACCACGTCGAAGAATCGCATCATCATAACCTGGCACCGGTACCGGCCCCCTGACTACAGGGATCTCATCAGCTTCACCG
TTTACTACAAGGAAGCACCCTTTAAGAATGTCACAGAGTATGATGGGCAGGATGCCTGCGGCTCCAACAGCTGGAACATGGTGGACGTGG
ACCTCCCGCCCAACAAGGACGTGGAGCCCGGCATCTTACTACATGGGCTGAAGCCCTGGACTCAGTACGCCGTTTACGTCAAGGCTGTGA
CCCTCACCATGGTGGAGAACGACCATATCCGTGGGGCCAAGAGTGAGATCTTGTACATTCGCACCAATGCTTCAGTTCCTTCCATTCCCT
TGGACGTTCTTTCAGCATCGAACTCCTCTTCTCAGTTAATCGTGAAGTGGAACCCTCCCTCTCTGCCCAACGGCAACCTGAGTTACTACA
TTGTGCGCTGGCAGCGGCAGCCTCAGGACGGCTACCTTTACCGGCACAATTACTGCTCCAAAGACAAAATCCCCATCAGGAAGTATGCCG
ACGGCACCATCGACATTGAGGAGGTCACAGAGAACCCCAAGACTGAGGTGTGTGGTGGGGAGAAAGGGCCTTGCTGCGCCTGCCCCAAAA
CTGAAGCCGAGAAGCAGGCCGAGAAGGAGGAGGCTGAATACCGCAAAGTCTTTGAGAATTTCCTGCACAACTCCATCTTCGTGCCCAGAC
CTGAAAGGAAGCGGAGAGATGTCATGCAAGTGGCCAACACCACCATGTCCAGCCGAAGCAGGAACACCACGGCCGCAGACACCTACAACA
TCACCGACCCGGAAGAGCTGGAGACAGAGTACCCTTTCTTTGAGAGCAGAGTGGATAACAAGGAGAGAACTGTCATTTCTAACCTTCGGC
CTTTCACATTGTACCGCATCGATATCCACAGCTGCAACCACGAGGCTGAGAAGCTGGGCTGCAGCGCCTCCAACTTCGTCTTTGCAAGGA
CTATGCCCGCAGAAGGAGCAGATGACATTCCTGGGCCAGTGACCTGGGAGCCAAGGCCTGAAAACTCCATCTTTTTAAAGTGGCCGGAAC
CTGAGAATCCCAATGGATTGATTCTAATGTATGAAATAAAATACGGATCACAAGTTGAGGATCAGCGAGAATGTGTGTCCAGACAGGAAT
ACAGGAAGTATGGAGGGGCCAAGCTAAACCGGCTAAACCCGGGGAACTACACAGCCCGGATTCAGGCCACATCTCTCTCTGGGAATGGGT
CGTGGACAGATCCTGTGTTCTTCTATGTCCAGGCCAAAACAGGATATGAAAACTTCATCCATCTGATCATCGCTCTGCCCGTCGCTGTCC
TGTTGATCGTGGGAGGGTTGGTGATTATGCTGTACGTCTTCCATAGAAAGAGAAATAACAGCAGGCTGGGGAATGGAGTGCTGTATGCCT
CTGTGAACCCGGAGTACTTCAGCGCTGCTGATGTGTACGTTCCTGATGAGTGGGAGGTGGCTCGGGAGAAGATCACCATGAGCCGGGAAC
TTGGGCAGGGGTCGTTTGGGATGGTCTATGAAGGAGTTGCCAAGGGTGTGGTGAAAGATGAACCTGAAACCAGAGTGGCCATTAAAACAG
TGAACGAGGCCGCAAGCATGCGTGAGAGGATTGAGTTTCTCAACGAAGCTTCTGTGATGAAGGAGTTCAATTGTCACCATGTGGTGCGAT
TGCTGGGTGTGGTGTCCCAAGGCCAGCCAACACTGGTCATCATGGAACTGATGACACGGGGCGATCTCAAAAGTTATCTCCGGTCTCTGA
GGCCAGAAATGGAGAATAATCCAGTCCTAGCACCTCCAAGCCTGAGCAAGATGATTCAGATGGCCGGAGAGATTGCAGACGGCATGGCAT
ACCTCAACGCCAATAAGTTCGTCCACAGAGACCTTGCTGCCCGGAATTGCATGGTAGCCGAAGATTTCACAGTCAAAATCGGAGATTTTG
GTATGACGCGAGATATCTATGAGACAGACTATTACCGGAAAGGAGGGAAAGGGCTGCTGCCCGTGCGCTGGATGTCTCCTGAGTCCCTCA
AGGATGGAGTCTTCACCACTTACTCGGACGTCTGGTCCTTCGGGGTCGTCCTCTGGGAGATCGCCACACTGGCCGAGCAGCCCTACCAGG
GCTTGTCCAACGAGCAAGTCCTTCGCTTCGTCATGGAGGGCGGCCTTCTGGACAAGCCAGACAACTGTCCTGACATGCTGTTTGAACTGA
TGCGCATGTGCTGGCAGTATAACCCCAAGATGAGGCCTTCCTTCCTGGAGATCATCAGCAGCATCAAAGAGGAGATGGAGCCTGGCTTCC
GGGAGGTCTCCTTCTACTACAGCGAGGAGAACAAGCTGCCCGAGCCGGAGGAGCTGGACCTGGAGCCAGAGAACATGGAGAGCGTCCCCC
TGGACCCCTCGGCCTCCTCGTCCTCCCTGCCACTGCCCGACAGACACTCAGGACACAAGGCCGAGAACGGCCCCGGCCCTGGGGTGCTGG
TCCTCCGCGCCAGCTTCGACGAGAGACAGCCTTACGCCCACATGAACGGGGGCCGCAAGAACGAGCGGGCCTTGCCGCTGCCCCAGTCTT
CGACCTGCTGATCCTTGGATCCTGAATCTGTGCAAACAGTAACGTGTGCGCACGCGCAGCGGGGTGGGGGGGGAGAGAGAGTTTTAACAA
TCCATTCACAAGCCTCCTGTACCTCAGTGGATCTTCAGAACTGCCCTTGCTGCCCGCGGGAGACAGCTTCTCTGCAGTAAAACACATTTG
GGATGTTCCTTTTTTCAATATGCAAGCAGCTTTTTATTCCCTGCCCAAACCCTTAACTGACATGGGCCTTTAAGAACCTTAATGACAACA
CTTAATAGCAACAGAGCACTTGAGAACCAGTCTCCTCACTCTGTCCCTGTCCTTCCCTGTTCTCCCTTTCTCTCTCCTCTCTGCTTCATA
ACGGAAAAATAATTGCCACAAGTCCAGCTGGGAAGCCCTTTTTATCAGTTTGAGGAAGTGGCTGTCCCTGTGGCCCCATCCAACCACTGT
ACACACCCGCCTGACACCGTGGGTCATTACAAAAAAACACGTGGAGATGGAAATTTTTACCTTTATCTTTCACCTTTCTAGGGACATGAA
ATTTACAAAGGGCCATCGTTCATCCAAGGCTGTTACCATTTTAACGCTGCCTAATTTTGCCAAAATCCTGAACTTTCTCCCTCATCGGCC
CGGCGCTGATTCCTCGTGTCCGGAGGCATGGGTGAGCATGGCAGCTGGTTGCTCCATTTGAGAGACACGCTGGCGACACACTCCGTCCAT
CCGACTGCCCCTGCTGTGCTGCTCAAGGCCACAGGCACACAGGTCTCATTGCTTCTGACTAGATTATTATTTGGGGGAACTGGACACAAT
AGGTCTTTCTCTCAGTGAAGGTGGGGAGAAGCTGAACCGGCTTCCCTGCCCTGCCTCCCCAGCCCCCTGCCCAACCCCCAAGAATCTGGT
GGCCATGGGCCCCGAAGCAGCCTGGCGGACAGGCTTGGAGTCAAGGGGCCCCATGCCTGCTTCTCTCCCAGCCCCAGCTCCCCCGCCCGC
CCCCAAGGACACAGATGGGAAGGGGTTTCCAGGGACTCAGCCCCACTGTTGATGCAGGTTTGCAAGGAAAGAAATTCAAACACCACAACA
GCAGTAAGAAGAAAAGCAGTCAATGGATTCAAGCATTCTAAGCTTTGTTGACATTTTCTCTGTTCCTAGGACTTCTTCATGGGTCTTACA
GTTCTATGTTAGACCATGAAACATTTGCATACACATCGTCTTTAATGTCACTTTTATAACTTTTTTACGGTTCAGATATTCATCTATACG
TCTGTACAGAAAAAAAAAAGCTGCTATTTTTTTTGTTCTTGATCTTTGTGGATTTAATCTATGAAAACCTTCAGGTCCACCCTCTCCCCT
TTCTGCTCACTCCAAGAAACTTCTTATGCTTTGTACTAGAGTGCGTGACTTTCTTCCTCTTTTCCCGGTAATGGATACTTCTATCACATA
ATTTGCCATGAACTGTTGGATGCCTTTTTATAAATACATCCCCCATCCCTGCTCCCACCTGCCCCTTTAGTTGTTTTCTAACCCGTAGGC
TCTCTGGGCACGAGGCAGAAAGCAGGCCGGGCACCCATCCTGAGAGGGCCGCGCTCCTCTCCCCAGCCTGCCCTCACAGCATTGGAGCCT
GTTACAGTGCAAGACATGATACAAACTCAGGTCAGAAAAACAAAGGTTAAATATTTCACACGTCTTTGTTCAGTGTTTCCACTCACCGTG
GTTGAGAAGCCTCACCCTCTCTTTCCCTTGCCTTTGCTTAGGTTGTGACACACATATATATATATTTTTTTAATTCTTGGGTACAACAGC
AGTGTTAACCGCAGACACTAGGCATTTGGATTACTATTTTTCTTAATGGCTATTTAATCCTTCCATCCCACGAAAAACAGCTGCTGAGTC
CAAGGGAGCAGCAGAGCGTGGTCCGGCAGGGCCTGTTGTGGCCCTCGCCACCCCCCTCACCGGACCGACTGACCTGTCTTTGGAACCAGA
ACATCCCAAGGGAACTCCTTCGCACTGGCGTTGAGTGGGACCCCGGGATCCAGGCTGGCCCAGGGCGGCACCCTCAGGGCTGTGCCCGCT
GGAGTGCTAGGTGGAGGCAGCACAGACGCCACGGTGGCCCAAGAGCCCCTTTGCTTCTTGCTGGGGGACCAGGGCTGTGGTGCTGGCCCA
CTTTCCCTCGGCCAGGAATCCAGGTCCTTGGGGCCCAGGGGTCTTGTCTTGTTTCATTTTTAGCACTTCTCACCAGAGAGATGACAGCAC
AAGAGTTGCTTCTGGGATAGAAATGTTTAGGAGTAAGAACAAAGCTGGGATACGGTGATTGCTAGTTGTGACTGAAGATTCAACACAGAA
AAGAAAGTTTATACGGCTTTTTTGCTGGTCAGCAGTTTGTCCCACTGCTTTCTCTAGTCTCTATCCCATAGCGTGTTCCCTTTAAAAAAA
AAAAAAAGGTATTATATGTAGGAGTTTTCTTTTAATTTATTTTGTGATAAATTACCAGTTTCAATCACTGTAGAAAAGCCCCATTATGAA
TTTAAATTTCAAGGAAAGGGTGTGTGTGTGTGTATGTGTGGGGTGTGTGTGTGTGAGAGTGATGGGACAGTTCTTGATTTTTTGGGTTTT
TTTTCCCCCAAACATTTATCTACCTCACTCTTATTTTTTATATGTGTATATAGACAAAAGAATACATCTCACCTTTCTCAGCACCTGACA
ATAGGCCGTTGATACTGGTAACCTCATCCACGCCACAGGCGCCACACCCAGGTGATGCAGGGGGAAGCCAGGCTGTATTCCGGGGTCAAA
GCAACACTAACTCACCTCTCTGCTCATTTCAGACAGCTTGCCTTTTTCTGAGATGTCCTGTTTTGTGTTGCTTTTTTTGTTTTGTTTTCT
ATCTTGGTTTCCACCAAGGTGTTAGATTTCTCCTCCTCCTAGCCAGGTGGCCCTGTGAGGCCAACGAGGGCACCAGAGCACACCTGGGGG
AGCCACCAGGCTGTCCCTGGCTGGTTGTCTTTGGAACAAACTGCTTCTGTGCAGATGGAATGACCAACACATTTCGTCCTTAAGAGAGCA
GTGGTTCCTCAGGTTCTGAGGAGAGGAAGGTGTCCAGGCAGCACCATCTCTGTGCGAATCCCCAGGGTAAAGGCGTGGGGCATTGGGTTT
GCTCCCCTTGCTGCTGCTCCATCCCTGCAGGAGGCTCGCGCTGAGGCAGGACCGTGCGGCCATGGCTGCTGCATTCATTGAGCACAAAGG
TGCAGCTGCAGCAGCAGCTGGAGAGCAAGAGTCACCCAGCCTGTGCGCCAGAATGCAGAGGCTCCTGACCTCACAGCCAGTCCCTGATAG
AACACACGCAGGAGCAGAGTCCCCTCCCCCTCCAGGCTGCCCTCTCAACTTCTCCCTCACCTCCTTCCCTAGGGGTAGACAGAGATGTAC
CAAACCTTCCGGCTGGAAAGCCCAGTGGCCGGCGCCGAGGCTCGTGGCGTCACGCCCCCCCCGCCAGGGCTGTACCTCCGTCTCCCTGGT
CCTGCTGCTCACAGGACAGACGGCTCGCTCCCCTCTTCCAGCAGCTGCTCTTACAGGCACTGATGATTTCGCTGGGAAGTGTGGCGGGCA
GCTTTGCCTAAGCGTGGATGGCTCCTCGGCAATTCCAGCCTAAGTGAAGGCGCTCAGGAGCCTCCTGCTGGAACGCGACCCATCTCTCCC
AGGACCCCGGGGATCTTAAGGTCATTGAGAAATACTGTTGGATCAGGGTTTTGTTCTTCCACACTGTAGGTGACCCCTTGGAATAACGGC
CTCTCCTCTCGTGCACATACCTACCGGTTTCCACAACTGGATTTCTACAGATCATTCAGCTGGTTATAAGGGTTTTGTTTAAACTGTCCG
AGTTACTGATGTCATTTTGTTTTTGTTTTATGTAGGTAGCTTTTAAGTAGAAAACACTAACAGTGTAGTGCCCATCATAGCAAATGCTTC
AGAAACACCTCAATAAAAGAGAAAACTTGGCTTGTGTGATGGTGCAGTCACTTTACTGGACCAACCCACCCACCTTGACTATACCAAGGC
ATCATCTATCCACAGTTCTAGCCTAACTTCATGCTGATTTCTCTGCCTCTTGATTTTTCTCTGTGTGTTCCAAATAATCTTAAGCTGAGT
TGTGGCATTTTCCATGCAACCTCCTTCTGCCAGCAGCTCACACTGCTTGAAGTCATATGAACCACTGAGGCACATCATGGAATTGATGTG
AGCATTAAGACGTTCTCCCACACAGCCCTTCCCTGAGGCAGCAGGAGCTGGTGTGTACTGGAGACACTGTTGAACTTGATCAAGACCCAG
ACCACCCCAGGTCTCCTTCGTGGGATGTCATGACGTTTGACATACCTTTGGAACGAGCCTCCTCCTTGGAAGATGGAAGACCGTGTTCGT
GGCCGACCTGGCCTCTCCTGGCCTGTTTCTTAAGATGCGGAGTCACATTTCAATGGTACGAAAAGTGGCTTCGTAAAATAGAAGAGCAGT
CACTGTGGAACTACCAAATGGCGAGATGCTCGGTGCACATTGGGGTGCTTTGGGATAAAAGATTTATGAGCCAACTATTCTCTGGCACCA
GATTCTAGGCCAGTTTGTTCCACTGAAGCTTTTCCCACAGCAGTCCACCTCTGCAGGCTGGCAGCCGAATGGCTTGCCAGTGGCTCTGTG
GCAAGATCACACTGAGATCGATGGGTGAGAAGGCTAGGATGCTTGTCTAGTGTTCTTAGCTGTCACGTTGGCTCCTTCCAGGGTGGCCAG
ACGGTGTTGGCCACTCCCTTCTAAAACACAGGCGCCCTCCTGGTGACAGTGACCCGCCGTGGTATGCCTTGGCCCATTCCAGCAGTCCCA
GTTATGCATTTCAAGTTTGGGGTTTGTTCTTTTCGTTAATGTTCCTCTGTGTTGTCAGCTGTCTTCATTTCCTGGGCTAAGCAGCATTGG
GAGATGTGGACCAGAGATCCACTCCTTAAGAACCAGTGGCGAAAGACACTTTCTTTCTTCACTCTGAAGTAGCTGGTGGTACAAATGAGA
ACTTCAAGAGAGGATGTTATTTAGACTGAACCTCTGTTGCCAGAGATGCTGAAGATACAGACCTTGGACAGGTCAGAGGGTTTCATTTTT
GGCCTTCATCTTAGATGACTGGTTGCGTCATTTGGAGAAGTGAGTGCTCCTTGATGGTGGAATGACCGGGTGGTGGGTACAGAACCATTG
TCACAGGGATCCTGGCACAGAGAAGAGTTACGAGCAGCAGGGTGCAGGGCTTGGAAGGAATGTGGGCAAGGTTTTGAACTTGATTGTTCT
TGAAGCTATCAGACCACATCGAGGCTCAGCAGTCATCCGTGGGCATTTGGTTTCAACAAAGAAACCTAACATCCTACTCTGGAAACTGAT
CTCGGAGTTAAGGCGAATTGTTCAAGAACACAAACTACATCGCACTCGTCAGTTGTCAGTTCTGGGGCATGACTTTAGCGTTTTGTTTCT
GCGAGAACATAACGATCACTCATTTTTATGTCCCACGTGTGTGTGTCCGCATCTTTCTGGTCAACATTGTTTTAACTAGTCACTCATTAG
CGTTTTCAATAGGGCTCTTAAGTCCAGTAGATTACGGGTAGTCAGTTGACGAAGATCTGGTTTACAAGAACTAATTAAATGTTTCATTGC
ATTTTTGTAAGAACAGAATAATTTTATAAAATGTTTGTAGTTTATAATTGCCGAAAATAATTTAAAGACACTTTTTTTTTCTCTGTGTGT
GCAAATGTGTGTTTGTGATCCATTTTTTTTTTTTTTTTTTAGGACACCTGTTTACTAGCTAGCTTTACAATATGCCAAAAAAGGATTTCT
CCCTGACCCCATCCGTGGTTCACCCTCTTTTCCCCCCATGCTTTTTGCCCTAGTTTATAACAAAGGAATGATGATGATTTAAAAAGTAGT
TCTGTATCTTCAGTATCTTGGTCTTCCAGAACCCTCTGGTTGGGAAGGGGATCATTTTTTACTGGTCATTTCCCTTTGGAGTGTAGCTAC
TTTAACAGATGGAAAGAACCTCATTGGCCATGGAAACAGCCGAGGTGTTGGAGCCCAGCAGTGCATGGCACCGTTCGGCATCTGGCTTGA
TTGGTCTGGCTGCCGTCATTGTCAGCACAGTGCCATGGACATGGGAAGACTTGACTGCACAGCCAATGGTTTTCATGATGATTACAGCAT
ACACAGTGATCACATAAACGATGACAGCTATGGGGCACACAGGCCATTTGCTTACATGCCTCGTATCATGACTGATTACTGCTTTGTTAG
AACACAGAAGAGACCCTATTTTATTTAAGGCAGAACCCCGAAGATACGTATTTCCAATACAGAAAAGAATTTTTAATAAAAACTATAACA
TACACAAAAATTGGTTTTAAAGTTGACTCCACTTCCTCTAACTCCAGTGGATTGTTGGCCATGTCTCCCCAACTCCACAATATCTCTATC
ATGGGAAACACCTGGGGTTTTTGCGCTACATAGGAGAAAGATCTGGAAACTATTTGGGTTTTGTTTTCAACTTTTCATTTGGATGTTTGG
CGTTGCACACACACATCCACCGGTGGAAGAGACGCCCGGTGAAAACACCTGTCTGCTTTCTAAGCCAGTGAGGTTGAGGTGAGAGGTTTG
CCAGAGTTTGTCTACCTCTGGGTATCCCTTTGTCTGGGATAAAAAAAATCAAACCAGAAGGCGGGATGGAATGGATGCACCGCAAATAAT
GCATTTTCTGAGTTTTCTTGTTAAAAAAAAATTTTTTTAAGTAAGAAAAAAAAAGGTAATAACATGGCCAATTTGTTACATAAAATGACT
TTCTGTGTATAAATTATTCCTAAAAAATCCTGTTTATATAAAAAATCAGTAGATGAAAAAAATTTCAAAATGTTTTTGTATATTCTGTTG
TAAGAATTTATTCCTGTTATTGCGATATACTCTGGATTCTTTACATAATGGAAAAAAGAAACTGTCTATTTTGAATGGCTGAAGCTAAGG

>53178_53178_1_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000268150_IGF1R_chr15_99434554_ENST00000268035_length(amino acids)=1397AA_BP=243
MSSPACPFQRPRPRSMPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKGYAGNHCETKCVEPLG
LENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLN
GHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNVCPSTCGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPK
VCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWH
RYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTE
VCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYG
SQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNE
ASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGL
LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRH

--------------------------------------------------------------
>53178_53178_2_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000268150_IGF1R_chr15_99434554_ENST00000558762_length(transcript)=11325nt_BP=777nt
TGATTTATTCCGGTCCCAGAGGAGAAGGCGCCAGAACCCCGCGGGGTCTGAGCAGCCCAGCGTGCCCATTCCAGCGCCCGCGTCCCCGCA
GCATGCCGCGCCCCCGCCTGCTGGCCGCGCTGTGCGGCGCGCTGCTCTGCGCCCCCAGCCTCCTCGTCGCCCTGGATATCTGTTCCAAAA
ACCCCTGCCACAACGGTGGTTTATGCGAGGAGATTTCCCAAGAAGTGCGAGGAGATGTCTTCCCCTCGTACACCTGCACGTGCCTTAAGG
GCTACGCGGGCAACCACTGTGAGACGAAATGTGTCGAGCCACTGGGCCTGGAGAATGGGAACATTGCCAACTCACAGATCGCCGCCTCGT
CTGTGCGTGTGACCTTCTTGGGTTTGCAGCATTGGGTCCCGGAGCTGGCCCGCCTGAACCGCGCAGGCATGGTCAATGCCTGGACACCCA
GCAGCAATGACGATAACCCCTGGATCCAGGTGAACCTGCTGCGGAGGATGTGGGTAACAGGTGTGGTGACGCAGGGTGCCAGCCGCTTGG
CCAGTCATGAGTACCTGAAGGCCTTCAAGGTGGCCTACAGCCTTAATGGACACGAATTCGATTTCATCCATGATGTTAATAAAAAACACA
AGGAGTTTGTGGGTAACTGGAACAAAAACGCGGTGCATGTCAACCTGTTTGAGACCCCTGTGGAGGCTCAGTACGTGAGATTGTACCCCA
CGAGCTGCCACACGGCCTGCACTCTGCGCTTTGAGCTACTGGGCTGTGAGCTGAACGTGTGCCCAAGCACGTGTGGGAAGCGGGCGTGCA
CCGAGAACAATGAGTGCTGCCACCCCGAGTGCCTGGGCAGCTGCAGCGCGCCTGACAACGACACGGCCTGTGTAGCTTGCCGCCACTACT
ACTATGCCGGTGTCTGTGTGCCTGCCTGCCCGCCCAACACCTACAGGTTTGAGGGCTGGCGCTGTGTGGACCGTGACTTCTGCGCCAACA
TCCTCAGCGCCGAGAGCAGCGACTCCGAGGGGTTTGTGATCCACGACGGCGAGTGCATGCAGGAGTGCCCCTCGGGCTTCATCCGCAACG
GCAGCCAGAGCATGTACTGCATCCCTTGTGAAGGTCCTTGCCCGAAGGTCTGTGAGGAAGAAAAGAAAACAAAGACCATTGATTCTGTTA
CTTCTGCTCAGATGCTCCAAGGATGCACCATCTTCAAGGGCAATTTGCTCATTAACATCCGACGGGGGAATAACATTGCTTCAGAGCTGG
AGAACTTCATGGGGCTCATCGAGGTGGTGACGGGCTACGTGAAGATCCGCCATTCTCATGCCTTGGTCTCCTTGTCCTTCCTAAAAAACC
TTCGCCTCATCCTAGGAGAGGAGCAGCTAGAAGGGAATTACTCCTTCTACGTCCTCGACAACCAGAACTTGCAGCAACTGTGGGACTGGG
ACCACCGCAACCTGACCATCAAAGCAGGGAAAATGTACTTTGCTTTCAATCCCAAATTATGTGTTTCCGAAATTTACCGCATGGAGGAAG
TGACGGGGACTAAAGGGCGCCAAAGCAAAGGGGACATAAACACCAGGAACAACGGGGAGAGAGCCTCCTGTGAAAGTGACGTCCTGCATT
TCACCTCCACCACCACGTCGAAGAATCGCATCATCATAACCTGGCACCGGTACCGGCCCCCTGACTACAGGGATCTCATCAGCTTCACCG
TTTACTACAAGGAAGCACCCTTTAAGAATGTCACAGAGTATGATGGGCAGGATGCCTGCGGCTCCAACAGCTGGAACATGGTGGACGTGG
ACCTCCCGCCCAACAAGGACGTGGAGCCCGGCATCTTACTACATGGGCTGAAGCCCTGGACTCAGTACGCCGTTTACGTCAAGGCTGTGA
CCCTCACCATGGTGGAGAACGACCATATCCGTGGGGCCAAGAGTGAGATCTTGTACATTCGCACCAATGCTTCAGTTCCTTCCATTCCCT
TGGACGTTCTTTCAGCATCGAACTCCTCTTCTCAGTTAATCGTGAAGTGGAACCCTCCCTCTCTGCCCAACGGCAACCTGAGTTACTACA
TTGTGCGCTGGCAGCGGCAGCCTCAGGACGGCTACCTTTACCGGCACAATTACTGCTCCAAAGACAAAATCCCCATCAGGAAGTATGCCG
ACGGCACCATCGACATTGAGGAGGTCACAGAGAACCCCAAGACTGAGGTGTGTGGTGGGGAGAAAGGGCCTTGCTGCGCCTGCCCCAAAA
CTGAAGCCGAGAAGCAGGCCGAGAAGGAGGAGGCTGAATACCGCAAAGTCTTTGAGAATTTCCTGCACAACTCCATCTTCGTGCCCAGAC
CTGAAAGGAAGCGGAGAGATGTCATGCAAGTGGCCAACACCACCATGTCCAGCCGAAGCAGGAACACCACGGCCGCAGACACCTACAACA
TCACCGACCCGGAAGAGCTGGAGACAGAGTACCCTTTCTTTGAGAGCAGAGTGGATAACAAGGAGAGAACTGTCATTTCTAACCTTCGGC
CTTTCACATTGTACCGCATCGATATCCACAGCTGCAACCACGAGGCTGAGAAGCTGGGCTGCAGCGCCTCCAACTTCGTCTTTGCAAGGA
CTATGCCCGCAGAAGGAGCAGATGACATTCCTGGGCCAGTGACCTGGGAGCCAAGGCCTGAAAACTCCATCTTTTTAAAGTGGCCGGAAC
CTGAGAATCCCAATGGATTGATTCTAATGTATGAAATAAAATACGGATCACAAGTTGAGGATCAGCGAGAATGTGTGTCCAGACAGGAAT
ACAGGAAGTATGGAGGGGCCAAGCTAAACCGGCTAAACCCGGGGAACTACACAGCCCGGATTCAGGCCACATCTCTCTCTGGGAATGGGT
CGTGGACAGATCCTGTGTTCTTCTATGTCCAGGCCAAAAGATATGAAAACTTCATCCATCTGATCATCGCTCTGCCCGTCGCTGTCCTGT
TGATCGTGGGAGGGTTGGTGATTATGCTGTACGTCTTCCATAGAAAGAGAAATAACAGCAGGCTGGGGAATGGAGTGCTGTATGCCTCTG
TGAACCCGGAGTACTTCAGCGCTGCTGATGTGTACGTTCCTGATGAGTGGGAGGTGGCTCGGGAGAAGATCACCATGAGCCGGGAACTTG
GGCAGGGGTCGTTTGGGATGGTCTATGAAGGAGTTGCCAAGGGTGTGGTGAAAGATGAACCTGAAACCAGAGTGGCCATTAAAACAGTGA
ACGAGGCCGCAAGCATGCGTGAGAGGATTGAGTTTCTCAACGAAGCTTCTGTGATGAAGGAGTTCAATTGTCACCATGTGGTGCGATTGC
TGGGTGTGGTGTCCCAAGGCCAGCCAACACTGGTCATCATGGAACTGATGACACGGGGCGATCTCAAAAGTTATCTCCGGTCTCTGAGGC
CAGAAATGGAGAATAATCCAGTCCTAGCACCTCCAAGCCTGAGCAAGATGATTCAGATGGCCGGAGAGATTGCAGACGGCATGGCATACC
TCAACGCCAATAAGTTCGTCCACAGAGACCTTGCTGCCCGGAATTGCATGGTAGCCGAAGATTTCACAGTCAAAATCGGAGATTTTGGTA
TGACGCGAGATATCTATGAGACAGACTATTACCGGAAAGGAGGGAAAGGGCTGCTGCCCGTGCGCTGGATGTCTCCTGAGTCCCTCAAGG
ATGGAGTCTTCACCACTTACTCGGACGTCTGGTCCTTCGGGGTCGTCCTCTGGGAGATCGCCACACTGGCCGAGCAGCCCTACCAGGGCT
TGTCCAACGAGCAAGTCCTTCGCTTCGTCATGGAGGGCGGCCTTCTGGACAAGCCAGACAACTGTCCTGACATGCTGTTTGAACTGATGC
GCATGTGCTGGCAGTATAACCCCAAGATGAGGCCTTCCTTCCTGGAGATCATCAGCAGCATCAAAGAGGAGATGGAGCCTGGCTTCCGGG
AGGTCTCCTTCTACTACAGCGAGGAGAACAAGCTGCCCGAGCCGGAGGAGCTGGACCTGGAGCCAGAGAACATGGAGAGCGTCCCCCTGG
ACCCCTCGGCCTCCTCGTCCTCCCTGCCACTGCCCGACAGACACTCAGGACACAAGGCCGAGAACGGCCCCGGCCCTGGGGTGCTGGTCC
TCCGCGCCAGCTTCGACGAGAGACAGCCTTACGCCCACATGAACGGGGGCCGCAAGAACGAGCGGGCCTTGCCGCTGCCCCAGTCTTCGA
CCTGCTGATCCTTGGATCCTGAATCTGTGCAAACAGTAACGTGTGCGCACGCGCAGCGGGGTGGGGGGGGAGAGAGAGTTTTAACAATCC
ATTCACAAGCCTCCTGTACCTCAGTGGATCTTCAGAACTGCCCTTGCTGCCCGCGGGAGACAGCTTCTCTGCAGTAAAACACATTTGGGA
TGTTCCTTTTTTCAATATGCAAGCAGCTTTTTATTCCCTGCCCAAACCCTTAACTGACATGGGCCTTTAAGAACCTTAATGACAACACTT
AATAGCAACAGAGCACTTGAGAACCAGTCTCCTCACTCTGTCCCTGTCCTTCCCTGTTCTCCCTTTCTCTCTCCTCTCTGCTTCATAACG
GAAAAATAATTGCCACAAGTCCAGCTGGGAAGCCCTTTTTATCAGTTTGAGGAAGTGGCTGTCCCTGTGGCCCCATCCAACCACTGTACA
CACCCGCCTGACACCGTGGGTCATTACAAAAAAACACGTGGAGATGGAAATTTTTACCTTTATCTTTCACCTTTCTAGGGACATGAAATT
TACAAAGGGCCATCGTTCATCCAAGGCTGTTACCATTTTAACGCTGCCTAATTTTGCCAAAATCCTGAACTTTCTCCCTCATCGGCCCGG
CGCTGATTCCTCGTGTCCGGAGGCATGGGTGAGCATGGCAGCTGGTTGCTCCATTTGAGAGACACGCTGGCGACACACTCCGTCCATCCG
ACTGCCCCTGCTGTGCTGCTCAAGGCCACAGGCACACAGGTCTCATTGCTTCTGACTAGATTATTATTTGGGGGAACTGGACACAATAGG
TCTTTCTCTCAGTGAAGGTGGGGAGAAGCTGAACCGGCTTCCCTGCCCTGCCTCCCCAGCCCCCTGCCCAACCCCCAAGAATCTGGTGGC
CATGGGCCCCGAAGCAGCCTGGCGGACAGGCTTGGAGTCAAGGGGCCCCATGCCTGCTTCTCTCCCAGCCCCAGCTCCCCCGCCCGCCCC
CAAGGACACAGATGGGAAGGGGTTTCCAGGGACTCAGCCCCACTGTTGATGCAGGTTTGCAAGGAAAGAAATTCAAACACCACAACAGCA
GTAAGAAGAAAAGCAGTCAATGGATTCAAGCATTCTAAGCTTTGTTGACATTTTCTCTGTTCCTAGGACTTCTTCATGGGTCTTACAGTT
CTATGTTAGACCATGAAACATTTGCATACACATCGTCTTTAATGTCACTTTTATAACTTTTTTACGGTTCAGATATTCATCTATACGTCT
GTACAGAAAAAAAAAAGCTGCTATTTTTTTTGTTCTTGATCTTTGTGGATTTAATCTATGAAAACCTTCAGGTCCACCCTCTCCCCTTTC
TGCTCACTCCAAGAAACTTCTTATGCTTTGTACTAGAGTGCGTGACTTTCTTCCTCTTTTCCCGGTAATGGATACTTCTATCACATAATT
TGCCATGAACTGTTGGATGCCTTTTTATAAATACATCCCCCATCCCTGCTCCCACCTGCCCCTTTAGTTGTTTTCTAACCCGTAGGCTCT
CTGGGCACGAGGCAGAAAGCAGGCCGGGCACCCATCCTGAGAGGGCCGCGCTCCTCTCCCCAGCCTGCCCTCACAGCATTGGAGCCTGTT
ACAGTGCAAGACATGATACAAACTCAGGTCAGAAAAACAAAGGTTAAATATTTCACACGTCTTTGTTCAGTGTTTCCACTCACCGTGGTT
GAGAAGCCTCACCCTCTCTTTCCCTTGCCTTTGCTTAGGTTGTGACACACATATATATATATTTTTTTAATTCTTGGGTACAACAGCAGT
GTTAACCGCAGACACTAGGCATTTGGATTACTATTTTTCTTAATGGCTATTTAATCCTTCCATCCCACGAAAAACAGCTGCTGAGTCCAA
GGGAGCAGCAGAGCGTGGTCCGGCAGGGCCTGTTGTGGCCCTCGCCACCCCCCTCACCGGACCGACTGACCTGTCTTTGGAACCAGAACA
TCCCAAGGGAACTCCTTCGCACTGGCGTTGAGTGGGACCCCGGGATCCAGGCTGGCCCAGGGCGGCACCCTCAGGGCTGTGCCCGCTGGA
GTGCTAGGTGGAGGCAGCACAGACGCCACGGTGGCCCAAGAGCCCCTTTGCTTCTTGCTGGGGGACCAGGGCTGTGGTGCTGGCCCACTT
TCCCTCGGCCAGGAATCCAGGTCCTTGGGGCCCAGGGGTCTTGTCTTGTTTCATTTTTAGCACTTCTCACCAGAGAGATGACAGCACAAG
AGTTGCTTCTGGGATAGAAATGTTTAGGAGTAAGAACAAAGCTGGGATACGGTGATTGCTAGTTGTGACTGAAGATTCAACACAGAAAAG
AAAGTTTATACGGCTTTTTTGCTGGTCAGCAGTTTGTCCCACTGCTTTCTCTAGTCTCTATCCCATAGCGTGTTCCCTTTAAAAAAAAAA
AAAAGGTATTATATGTAGGAGTTTTCTTTTAATTTATTTTGTGATAAATTACCAGTTTCAATCACTGTAGAAAAGCCCCATTATGAATTT
AAATTTCAAGGAAAGGGTGTGTGTGTGTGTATGTGTGGGGTGTGTGTGTGTGAGAGTGATGGGACAGTTCTTGATTTTTTGGGTTTTTTT
TCCCCCAAACATTTATCTACCTCACTCTTATTTTTTATATGTGTATATAGACAAAAGAATACATCTCACCTTTCTCAGCACCTGACAATA
GGCCGTTGATACTGGTAACCTCATCCACGCCACAGGCGCCACACCCAGGTGATGCAGGGGGAAGCCAGGCTGTATTCCGGGGTCAAAGCA
ACACTAACTCACCTCTCTGCTCATTTCAGACAGCTTGCCTTTTTCTGAGATGTCCTGTTTTGTGTTGCTTTTTTTGTTTTGTTTTCTATC
TTGGTTTCCACCAAGGTGTTAGATTTCTCCTCCTCCTAGCCAGGTGGCCCTGTGAGGCCAACGAGGGCACCAGAGCACACCTGGGGGAGC
CACCAGGCTGTCCCTGGCTGGTTGTCTTTGGAACAAACTGCTTCTGTGCAGATGGAATGACCAACACATTTCGTCCTTAAGAGAGCAGTG
GTTCCTCAGGTTCTGAGGAGAGGAAGGTGTCCAGGCAGCACCATCTCTGTGCGAATCCCCAGGGTAAAGGCGTGGGGCATTGGGTTTGCT
CCCCTTGCTGCTGCTCCATCCCTGCAGGAGGCTCGCGCTGAGGCAGGACCGTGCGGCCATGGCTGCTGCATTCATTGAGCACAAAGGTGC
AGCTGCAGCAGCAGCTGGAGAGCAAGAGTCACCCAGCCTGTGCGCCAGAATGCAGAGGCTCCTGACCTCACAGCCAGTCCCTGATAGAAC
ACACGCAGGAGCAGAGTCCCCTCCCCCTCCAGGCTGCCCTCTCAACTTCTCCCTCACCTCCTTCCCTAGGGGTAGACAGAGATGTACCAA
ACCTTCCGGCTGGAAAGCCCAGTGGCCGGCGCCGAGGCTCGTGGCGTCACGCCCCCCCCGCCAGGGCTGTACCTCCGTCTCCCTGGTCCT
GCTGCTCACAGGACAGACGGCTCGCTCCCCTCTTCCAGCAGCTGCTCTTACAGGCACTGATGATTTCGCTGGGAAGTGTGGCGGGCAGCT
TTGCCTAAGCGTGGATGGCTCCTCGGCAATTCCAGCCTAAGTGAAGGCGCTCAGGAGCCTCCTGCTGGAACGCGACCCATCTCTCCCAGG
ACCCCGGGGATCTTAAGGTCATTGAGAAATACTGTTGGATCAGGGTTTTGTTCTTCCACACTGTAGGTGACCCCTTGGAATAACGGCCTC
TCCTCTCGTGCACATACCTACCGGTTTCCACAACTGGATTTCTACAGATCATTCAGCTGGTTATAAGGGTTTTGTTTAAACTGTCCGAGT
TACTGATGTCATTTTGTTTTTGTTTTATGTAGGTAGCTTTTAAGTAGAAAACACTAACAGTGTAGTGCCCATCATAGCAAATGCTTCAGA
AACACCTCAATAAAAGAGAAAACTTGGCTTGTGTGATGGTGCAGTCACTTTACTGGACCAACCCACCCACCTTGACTATACCAAGGCATC
ATCTATCCACAGTTCTAGCCTAACTTCATGCTGATTTCTCTGCCTCTTGATTTTTCTCTGTGTGTTCCAAATAATCTTAAGCTGAGTTGT
GGCATTTTCCATGCAACCTCCTTCTGCCAGCAGCTCACACTGCTTGAAGTCATATGAACCACTGAGGCACATCATGGAATTGATGTGAGC
ATTAAGACGTTCTCCCACACAGCCCTTCCCTGAGGCAGCAGGAGCTGGTGTGTACTGGAGACACTGTTGAACTTGATCAAGACCCAGACC
ACCCCAGGTCTCCTTCGTGGGATGTCATGACGTTTGACATACCTTTGGAACGAGCCTCCTCCTTGGAAGATGGAAGACCGTGTTCGTGGC
CGACCTGGCCTCTCCTGGCCTGTTTCTTAAGATGCGGAGTCACATTTCAATGGTACGAAAAGTGGCTTCGTAAAATAGAAGAGCAGTCAC
TGTGGAACTACCAAATGGCGAGATGCTCGGTGCACATTGGGGTGCTTTGGGATAAAAGATTTATGAGCCAACTATTCTCTGGCACCAGAT
TCTAGGCCAGTTTGTTCCACTGAAGCTTTTCCCACAGCAGTCCACCTCTGCAGGCTGGCAGCCGAATGGCTTGCCAGTGGCTCTGTGGCA
AGATCACACTGAGATCGATGGGTGAGAAGGCTAGGATGCTTGTCTAGTGTTCTTAGCTGTCACGTTGGCTCCTTCCAGGGTGGCCAGACG
GTGTTGGCCACTCCCTTCTAAAACACAGGCGCCCTCCTGGTGACAGTGACCCGCCGTGGTATGCCTTGGCCCATTCCAGCAGTCCCAGTT
ATGCATTTCAAGTTTGGGGTTTGTTCTTTTCGTTAATGTTCCTCTGTGTTGTCAGCTGTCTTCATTTCCTGGGCTAAGCAGCATTGGGAG
ATGTGGACCAGAGATCCACTCCTTAAGAACCAGTGGCGAAAGACACTTTCTTTCTTCACTCTGAAGTAGCTGGTGGTACAAATGAGAACT
TCAAGAGAGGATGTTATTTAGACTGAACCTCTGTTGCCAGAGATGCTGAAGATACAGACCTTGGACAGGTCAGAGGGTTTCATTTTTGGC
CTTCATCTTAGATGACTGGTTGCGTCATTTGGAGAAGTGAGTGCTCCTTGATGGTGGAATGACCGGGTGGTGGGTACAGAACCATTGTCA
CAGGGATCCTGGCACAGAGAAGAGTTACGAGCAGCAGGGTGCAGGGCTTGGAAGGAATGTGGGCAAGGTTTTGAACTTGATTGTTCTTGA
AGCTATCAGACCACATCGAGGCTCAGCAGTCATCCGTGGGCATTTGGTTTCAACAAAGAAACCTAACATCCTACTCTGGAAACTGATCTC
GGAGTTAAGGCGAATTGTTCAAGAACACAAACTACATCGCACTCGTCAGTTGTCAGTTCTGGGGCATGACTTTAGCGTTTTGTTTCTGCG
AGAACATAACGATCACTCATTTTTATGTCCCACGTGTGTGTGTCCGCATCTTTCTGGTCAACATTGTTTTAACTAGTCACTCATTAGCGT
TTTCAATAGGGCTCTTAAGTCCAGTAGATTACGGGTAGTCAGTTGACGAAGATCTGGTTTACAAGAACTAATTAAATGTTTCATTGCATT
TTTGTAAGAACAGAATAATTTTATAAAATGTTTGTAGTTTATAATTGCCGAAAATAATTTAAAGACACTTTTTTTTTCTCTGTGTGTGCA
AATGTGTGTTTGTGATCCATTTTTTTTTTTTTTTTTTAGGACACCTGTTTACTAGCTAGCTTTACAATATGCCAAAAAAGGATTTCTCCC
TGACCCCATCCGTGGTTCACCCTCTTTTCCCCCCATGCTTTTTGCCCTAGTTTATAACAAAGGAATGATGATGATTTAAAAAGTAGTTCT
GTATCTTCAGTATCTTGGTCTTCCAGAACCCTCTGGTTGGGAAGGGGATCATTTTTTACTGGTCATTTCCCTTTGGAGTGTAGCTACTTT
AACAGATGGAAAGAACCTCATTGGCCATGGAAACAGCCGAGGTGTTGGAGCCCAGCAGTGCATGGCACCGTTCGGCATCTGGCTTGATTG
GTCTGGCTGCCGTCATTGTCAGCACAGTGCCATGGACATGGGAAGACTTGACTGCACAGCCAATGGTTTTCATGATGATTACAGCATACA
CAGTGATCACATAAACGATGACAGCTATGGGGCACACAGGCCATTTGCTTACATGCCTCGTATCATGACTGATTACTGCTTTGTTAGAAC
ACAGAAGAGACCCTATTTTATTTAAGGCAGAACCCCGAAGATACGTATTTCCAATACAGAAAAGAATTTTTAATAAAAACTATAACATAC
ACAAAAATTGGTTTTAAAGTTGACTCCACTTCCTCTAACTCCAGTGGATTGTTGGCCATGTCTCCCCAACTCCACAATATCTCTATCATG
GGAAACACCTGGGGTTTTTGCGCTACATAGGAGAAAGATCTGGAAACTATTTGGGTTTTGTTTTCAACTTTTCATTTGGATGTTTGGCGT
TGCACACACACATCCACCGGTGGAAGAGACGCCCGGTGAAAACACCTGTCTGCTTTCTAAGCCAGTGAGGTTGAGGTGAGAGGTTTGCCA
GAGTTTGTCTACCTCTGGGTATCCCTTTGTCTGGGATAAAAAAAATCAAACCAGAAGGCGGGATGGAATGGATGCACCGCAAATAATGCA
TTTTCTGAGTTTTCTTGTTAAAAAAAAATTTTTTTAAGTAAGAAAAAAAAAGGTAATAACATGGCCAATTTGTTACATAAAATGACTTTC
TGTGTATAAATTATTCCTAAAAAATCCTGTTTATATAAAAAATCAGTAGATGAAAAAAATTTCAAAATGTTTTTGTATATTCTGTTGTAA
GAATTTATTCCTGTTATTGCGATATACTCTGGATTCTTTACATAATGGAAAAAAGAAACTGTCTATTTTGAATGGCTGAAGCTAAGGCAA

>53178_53178_2_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000268150_IGF1R_chr15_99434554_ENST00000558762_length(amino acids)=1396AA_BP=243
MSSPACPFQRPRPRSMPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKGYAGNHCETKCVEPLG
LENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLN
GHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNVCPSTCGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPK
VCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWH
RYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTE
VCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYG
SQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKRYENFIHLIIALPVAVLLIVGGLVIMLYVFHRK
RNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEA
SVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNC
MVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLL
DKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHS

--------------------------------------------------------------
>53178_53178_3_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000268151_IGF1R_chr15_99434554_ENST00000268035_length(transcript)=11299nt_BP=747nt
CCAGAACCCCGCGGGGTCTGAGCAGCCCAGCGTGCCCATTCCAGCGCCCGCGTCCCCGCAGCATGCCGCGCCCCCGCCTGCTGGCCGCGC
TGTGCGGCGCGCTGCTCTGCGCCCCCAGCCTCCTCGTCGCCCTGGATATCTGTTCCAAAAACCCCTGCCACAACGGTGGTTTATGCGAGG
AGATTTCCCAAGAAGTGCGAGGAGATGTCTTCCCCTCGTACACCTGCACGTGCCTTAAGGGCTACGCGGGCAACCACTGTGAGACGAAAT
GTGTCGAGCCACTGGGCCTGGAGAATGGGAACATTGCCAACTCACAGATCGCCGCCTCGTCTGTGCGTGTGACCTTCTTGGGTTTGCAGC
ATTGGGTCCCGGAGCTGGCCCGCCTGAACCGCGCAGGCATGGTCAATGCCTGGACACCCAGCAGCAATGACGATAACCCCTGGATCCAGG
TGAACCTGCTGCGGAGGATGTGGGTAACAGGTGTGGTGACGCAGGGTGCCAGCCGCTTGGCCAGTCATGAGTACCTGAAGGCCTTCAAGG
TGGCCTACAGCCTTAATGGACACGAATTCGATTTCATCCATGATGTTAATAAAAAACACAAGGAGTTTGTGGGTAACTGGAACAAAAACG
CGGTGCATGTCAACCTGTTTGAGACCCCTGTGGAGGCTCAGTACGTGAGATTGTACCCCACGAGCTGCCACACGGCCTGCACTCTGCGCT
TTGAGCTACTGGGCTGTGAGCTGAACGTGTGCCCAAGCACGTGTGGGAAGCGGGCGTGCACCGAGAACAATGAGTGCTGCCACCCCGAGT
GCCTGGGCAGCTGCAGCGCGCCTGACAACGACACGGCCTGTGTAGCTTGCCGCCACTACTACTATGCCGGTGTCTGTGTGCCTGCCTGCC
CGCCCAACACCTACAGGTTTGAGGGCTGGCGCTGTGTGGACCGTGACTTCTGCGCCAACATCCTCAGCGCCGAGAGCAGCGACTCCGAGG
GGTTTGTGATCCACGACGGCGAGTGCATGCAGGAGTGCCCCTCGGGCTTCATCCGCAACGGCAGCCAGAGCATGTACTGCATCCCTTGTG
AAGGTCCTTGCCCGAAGGTCTGTGAGGAAGAAAAGAAAACAAAGACCATTGATTCTGTTACTTCTGCTCAGATGCTCCAAGGATGCACCA
TCTTCAAGGGCAATTTGCTCATTAACATCCGACGGGGGAATAACATTGCTTCAGAGCTGGAGAACTTCATGGGGCTCATCGAGGTGGTGA
CGGGCTACGTGAAGATCCGCCATTCTCATGCCTTGGTCTCCTTGTCCTTCCTAAAAAACCTTCGCCTCATCCTAGGAGAGGAGCAGCTAG
AAGGGAATTACTCCTTCTACGTCCTCGACAACCAGAACTTGCAGCAACTGTGGGACTGGGACCACCGCAACCTGACCATCAAAGCAGGGA
AAATGTACTTTGCTTTCAATCCCAAATTATGTGTTTCCGAAATTTACCGCATGGAGGAAGTGACGGGGACTAAAGGGCGCCAAAGCAAAG
GGGACATAAACACCAGGAACAACGGGGAGAGAGCCTCCTGTGAAAGTGACGTCCTGCATTTCACCTCCACCACCACGTCGAAGAATCGCA
TCATCATAACCTGGCACCGGTACCGGCCCCCTGACTACAGGGATCTCATCAGCTTCACCGTTTACTACAAGGAAGCACCCTTTAAGAATG
TCACAGAGTATGATGGGCAGGATGCCTGCGGCTCCAACAGCTGGAACATGGTGGACGTGGACCTCCCGCCCAACAAGGACGTGGAGCCCG
GCATCTTACTACATGGGCTGAAGCCCTGGACTCAGTACGCCGTTTACGTCAAGGCTGTGACCCTCACCATGGTGGAGAACGACCATATCC
GTGGGGCCAAGAGTGAGATCTTGTACATTCGCACCAATGCTTCAGTTCCTTCCATTCCCTTGGACGTTCTTTCAGCATCGAACTCCTCTT
CTCAGTTAATCGTGAAGTGGAACCCTCCCTCTCTGCCCAACGGCAACCTGAGTTACTACATTGTGCGCTGGCAGCGGCAGCCTCAGGACG
GCTACCTTTACCGGCACAATTACTGCTCCAAAGACAAAATCCCCATCAGGAAGTATGCCGACGGCACCATCGACATTGAGGAGGTCACAG
AGAACCCCAAGACTGAGGTGTGTGGTGGGGAGAAAGGGCCTTGCTGCGCCTGCCCCAAAACTGAAGCCGAGAAGCAGGCCGAGAAGGAGG
AGGCTGAATACCGCAAAGTCTTTGAGAATTTCCTGCACAACTCCATCTTCGTGCCCAGACCTGAAAGGAAGCGGAGAGATGTCATGCAAG
TGGCCAACACCACCATGTCCAGCCGAAGCAGGAACACCACGGCCGCAGACACCTACAACATCACCGACCCGGAAGAGCTGGAGACAGAGT
ACCCTTTCTTTGAGAGCAGAGTGGATAACAAGGAGAGAACTGTCATTTCTAACCTTCGGCCTTTCACATTGTACCGCATCGATATCCACA
GCTGCAACCACGAGGCTGAGAAGCTGGGCTGCAGCGCCTCCAACTTCGTCTTTGCAAGGACTATGCCCGCAGAAGGAGCAGATGACATTC
CTGGGCCAGTGACCTGGGAGCCAAGGCCTGAAAACTCCATCTTTTTAAAGTGGCCGGAACCTGAGAATCCCAATGGATTGATTCTAATGT
ATGAAATAAAATACGGATCACAAGTTGAGGATCAGCGAGAATGTGTGTCCAGACAGGAATACAGGAAGTATGGAGGGGCCAAGCTAAACC
GGCTAAACCCGGGGAACTACACAGCCCGGATTCAGGCCACATCTCTCTCTGGGAATGGGTCGTGGACAGATCCTGTGTTCTTCTATGTCC
AGGCCAAAACAGGATATGAAAACTTCATCCATCTGATCATCGCTCTGCCCGTCGCTGTCCTGTTGATCGTGGGAGGGTTGGTGATTATGC
TGTACGTCTTCCATAGAAAGAGAAATAACAGCAGGCTGGGGAATGGAGTGCTGTATGCCTCTGTGAACCCGGAGTACTTCAGCGCTGCTG
ATGTGTACGTTCCTGATGAGTGGGAGGTGGCTCGGGAGAAGATCACCATGAGCCGGGAACTTGGGCAGGGGTCGTTTGGGATGGTCTATG
AAGGAGTTGCCAAGGGTGTGGTGAAAGATGAACCTGAAACCAGAGTGGCCATTAAAACAGTGAACGAGGCCGCAAGCATGCGTGAGAGGA
TTGAGTTTCTCAACGAAGCTTCTGTGATGAAGGAGTTCAATTGTCACCATGTGGTGCGATTGCTGGGTGTGGTGTCCCAAGGCCAGCCAA
CACTGGTCATCATGGAACTGATGACACGGGGCGATCTCAAAAGTTATCTCCGGTCTCTGAGGCCAGAAATGGAGAATAATCCAGTCCTAG
CACCTCCAAGCCTGAGCAAGATGATTCAGATGGCCGGAGAGATTGCAGACGGCATGGCATACCTCAACGCCAATAAGTTCGTCCACAGAG
ACCTTGCTGCCCGGAATTGCATGGTAGCCGAAGATTTCACAGTCAAAATCGGAGATTTTGGTATGACGCGAGATATCTATGAGACAGACT
ATTACCGGAAAGGAGGGAAAGGGCTGCTGCCCGTGCGCTGGATGTCTCCTGAGTCCCTCAAGGATGGAGTCTTCACCACTTACTCGGACG
TCTGGTCCTTCGGGGTCGTCCTCTGGGAGATCGCCACACTGGCCGAGCAGCCCTACCAGGGCTTGTCCAACGAGCAAGTCCTTCGCTTCG
TCATGGAGGGCGGCCTTCTGGACAAGCCAGACAACTGTCCTGACATGCTGTTTGAACTGATGCGCATGTGCTGGCAGTATAACCCCAAGA
TGAGGCCTTCCTTCCTGGAGATCATCAGCAGCATCAAAGAGGAGATGGAGCCTGGCTTCCGGGAGGTCTCCTTCTACTACAGCGAGGAGA
ACAAGCTGCCCGAGCCGGAGGAGCTGGACCTGGAGCCAGAGAACATGGAGAGCGTCCCCCTGGACCCCTCGGCCTCCTCGTCCTCCCTGC
CACTGCCCGACAGACACTCAGGACACAAGGCCGAGAACGGCCCCGGCCCTGGGGTGCTGGTCCTCCGCGCCAGCTTCGACGAGAGACAGC
CTTACGCCCACATGAACGGGGGCCGCAAGAACGAGCGGGCCTTGCCGCTGCCCCAGTCTTCGACCTGCTGATCCTTGGATCCTGAATCTG
TGCAAACAGTAACGTGTGCGCACGCGCAGCGGGGTGGGGGGGGAGAGAGAGTTTTAACAATCCATTCACAAGCCTCCTGTACCTCAGTGG
ATCTTCAGAACTGCCCTTGCTGCCCGCGGGAGACAGCTTCTCTGCAGTAAAACACATTTGGGATGTTCCTTTTTTCAATATGCAAGCAGC
TTTTTATTCCCTGCCCAAACCCTTAACTGACATGGGCCTTTAAGAACCTTAATGACAACACTTAATAGCAACAGAGCACTTGAGAACCAG
TCTCCTCACTCTGTCCCTGTCCTTCCCTGTTCTCCCTTTCTCTCTCCTCTCTGCTTCATAACGGAAAAATAATTGCCACAAGTCCAGCTG
GGAAGCCCTTTTTATCAGTTTGAGGAAGTGGCTGTCCCTGTGGCCCCATCCAACCACTGTACACACCCGCCTGACACCGTGGGTCATTAC
AAAAAAACACGTGGAGATGGAAATTTTTACCTTTATCTTTCACCTTTCTAGGGACATGAAATTTACAAAGGGCCATCGTTCATCCAAGGC
TGTTACCATTTTAACGCTGCCTAATTTTGCCAAAATCCTGAACTTTCTCCCTCATCGGCCCGGCGCTGATTCCTCGTGTCCGGAGGCATG
GGTGAGCATGGCAGCTGGTTGCTCCATTTGAGAGACACGCTGGCGACACACTCCGTCCATCCGACTGCCCCTGCTGTGCTGCTCAAGGCC
ACAGGCACACAGGTCTCATTGCTTCTGACTAGATTATTATTTGGGGGAACTGGACACAATAGGTCTTTCTCTCAGTGAAGGTGGGGAGAA
GCTGAACCGGCTTCCCTGCCCTGCCTCCCCAGCCCCCTGCCCAACCCCCAAGAATCTGGTGGCCATGGGCCCCGAAGCAGCCTGGCGGAC
AGGCTTGGAGTCAAGGGGCCCCATGCCTGCTTCTCTCCCAGCCCCAGCTCCCCCGCCCGCCCCCAAGGACACAGATGGGAAGGGGTTTCC
AGGGACTCAGCCCCACTGTTGATGCAGGTTTGCAAGGAAAGAAATTCAAACACCACAACAGCAGTAAGAAGAAAAGCAGTCAATGGATTC
AAGCATTCTAAGCTTTGTTGACATTTTCTCTGTTCCTAGGACTTCTTCATGGGTCTTACAGTTCTATGTTAGACCATGAAACATTTGCAT
ACACATCGTCTTTAATGTCACTTTTATAACTTTTTTACGGTTCAGATATTCATCTATACGTCTGTACAGAAAAAAAAAAGCTGCTATTTT
TTTTGTTCTTGATCTTTGTGGATTTAATCTATGAAAACCTTCAGGTCCACCCTCTCCCCTTTCTGCTCACTCCAAGAAACTTCTTATGCT
TTGTACTAGAGTGCGTGACTTTCTTCCTCTTTTCCCGGTAATGGATACTTCTATCACATAATTTGCCATGAACTGTTGGATGCCTTTTTA
TAAATACATCCCCCATCCCTGCTCCCACCTGCCCCTTTAGTTGTTTTCTAACCCGTAGGCTCTCTGGGCACGAGGCAGAAAGCAGGCCGG
GCACCCATCCTGAGAGGGCCGCGCTCCTCTCCCCAGCCTGCCCTCACAGCATTGGAGCCTGTTACAGTGCAAGACATGATACAAACTCAG
GTCAGAAAAACAAAGGTTAAATATTTCACACGTCTTTGTTCAGTGTTTCCACTCACCGTGGTTGAGAAGCCTCACCCTCTCTTTCCCTTG
CCTTTGCTTAGGTTGTGACACACATATATATATATTTTTTTAATTCTTGGGTACAACAGCAGTGTTAACCGCAGACACTAGGCATTTGGA
TTACTATTTTTCTTAATGGCTATTTAATCCTTCCATCCCACGAAAAACAGCTGCTGAGTCCAAGGGAGCAGCAGAGCGTGGTCCGGCAGG
GCCTGTTGTGGCCCTCGCCACCCCCCTCACCGGACCGACTGACCTGTCTTTGGAACCAGAACATCCCAAGGGAACTCCTTCGCACTGGCG
TTGAGTGGGACCCCGGGATCCAGGCTGGCCCAGGGCGGCACCCTCAGGGCTGTGCCCGCTGGAGTGCTAGGTGGAGGCAGCACAGACGCC
ACGGTGGCCCAAGAGCCCCTTTGCTTCTTGCTGGGGGACCAGGGCTGTGGTGCTGGCCCACTTTCCCTCGGCCAGGAATCCAGGTCCTTG
GGGCCCAGGGGTCTTGTCTTGTTTCATTTTTAGCACTTCTCACCAGAGAGATGACAGCACAAGAGTTGCTTCTGGGATAGAAATGTTTAG
GAGTAAGAACAAAGCTGGGATACGGTGATTGCTAGTTGTGACTGAAGATTCAACACAGAAAAGAAAGTTTATACGGCTTTTTTGCTGGTC
AGCAGTTTGTCCCACTGCTTTCTCTAGTCTCTATCCCATAGCGTGTTCCCTTTAAAAAAAAAAAAAAGGTATTATATGTAGGAGTTTTCT
TTTAATTTATTTTGTGATAAATTACCAGTTTCAATCACTGTAGAAAAGCCCCATTATGAATTTAAATTTCAAGGAAAGGGTGTGTGTGTG
TGTATGTGTGGGGTGTGTGTGTGTGAGAGTGATGGGACAGTTCTTGATTTTTTGGGTTTTTTTTCCCCCAAACATTTATCTACCTCACTC
TTATTTTTTATATGTGTATATAGACAAAAGAATACATCTCACCTTTCTCAGCACCTGACAATAGGCCGTTGATACTGGTAACCTCATCCA
CGCCACAGGCGCCACACCCAGGTGATGCAGGGGGAAGCCAGGCTGTATTCCGGGGTCAAAGCAACACTAACTCACCTCTCTGCTCATTTC
AGACAGCTTGCCTTTTTCTGAGATGTCCTGTTTTGTGTTGCTTTTTTTGTTTTGTTTTCTATCTTGGTTTCCACCAAGGTGTTAGATTTC
TCCTCCTCCTAGCCAGGTGGCCCTGTGAGGCCAACGAGGGCACCAGAGCACACCTGGGGGAGCCACCAGGCTGTCCCTGGCTGGTTGTCT
TTGGAACAAACTGCTTCTGTGCAGATGGAATGACCAACACATTTCGTCCTTAAGAGAGCAGTGGTTCCTCAGGTTCTGAGGAGAGGAAGG
TGTCCAGGCAGCACCATCTCTGTGCGAATCCCCAGGGTAAAGGCGTGGGGCATTGGGTTTGCTCCCCTTGCTGCTGCTCCATCCCTGCAG
GAGGCTCGCGCTGAGGCAGGACCGTGCGGCCATGGCTGCTGCATTCATTGAGCACAAAGGTGCAGCTGCAGCAGCAGCTGGAGAGCAAGA
GTCACCCAGCCTGTGCGCCAGAATGCAGAGGCTCCTGACCTCACAGCCAGTCCCTGATAGAACACACGCAGGAGCAGAGTCCCCTCCCCC
TCCAGGCTGCCCTCTCAACTTCTCCCTCACCTCCTTCCCTAGGGGTAGACAGAGATGTACCAAACCTTCCGGCTGGAAAGCCCAGTGGCC
GGCGCCGAGGCTCGTGGCGTCACGCCCCCCCCGCCAGGGCTGTACCTCCGTCTCCCTGGTCCTGCTGCTCACAGGACAGACGGCTCGCTC
CCCTCTTCCAGCAGCTGCTCTTACAGGCACTGATGATTTCGCTGGGAAGTGTGGCGGGCAGCTTTGCCTAAGCGTGGATGGCTCCTCGGC
AATTCCAGCCTAAGTGAAGGCGCTCAGGAGCCTCCTGCTGGAACGCGACCCATCTCTCCCAGGACCCCGGGGATCTTAAGGTCATTGAGA
AATACTGTTGGATCAGGGTTTTGTTCTTCCACACTGTAGGTGACCCCTTGGAATAACGGCCTCTCCTCTCGTGCACATACCTACCGGTTT
CCACAACTGGATTTCTACAGATCATTCAGCTGGTTATAAGGGTTTTGTTTAAACTGTCCGAGTTACTGATGTCATTTTGTTTTTGTTTTA
TGTAGGTAGCTTTTAAGTAGAAAACACTAACAGTGTAGTGCCCATCATAGCAAATGCTTCAGAAACACCTCAATAAAAGAGAAAACTTGG
CTTGTGTGATGGTGCAGTCACTTTACTGGACCAACCCACCCACCTTGACTATACCAAGGCATCATCTATCCACAGTTCTAGCCTAACTTC
ATGCTGATTTCTCTGCCTCTTGATTTTTCTCTGTGTGTTCCAAATAATCTTAAGCTGAGTTGTGGCATTTTCCATGCAACCTCCTTCTGC
CAGCAGCTCACACTGCTTGAAGTCATATGAACCACTGAGGCACATCATGGAATTGATGTGAGCATTAAGACGTTCTCCCACACAGCCCTT
CCCTGAGGCAGCAGGAGCTGGTGTGTACTGGAGACACTGTTGAACTTGATCAAGACCCAGACCACCCCAGGTCTCCTTCGTGGGATGTCA
TGACGTTTGACATACCTTTGGAACGAGCCTCCTCCTTGGAAGATGGAAGACCGTGTTCGTGGCCGACCTGGCCTCTCCTGGCCTGTTTCT
TAAGATGCGGAGTCACATTTCAATGGTACGAAAAGTGGCTTCGTAAAATAGAAGAGCAGTCACTGTGGAACTACCAAATGGCGAGATGCT
CGGTGCACATTGGGGTGCTTTGGGATAAAAGATTTATGAGCCAACTATTCTCTGGCACCAGATTCTAGGCCAGTTTGTTCCACTGAAGCT
TTTCCCACAGCAGTCCACCTCTGCAGGCTGGCAGCCGAATGGCTTGCCAGTGGCTCTGTGGCAAGATCACACTGAGATCGATGGGTGAGA
AGGCTAGGATGCTTGTCTAGTGTTCTTAGCTGTCACGTTGGCTCCTTCCAGGGTGGCCAGACGGTGTTGGCCACTCCCTTCTAAAACACA
GGCGCCCTCCTGGTGACAGTGACCCGCCGTGGTATGCCTTGGCCCATTCCAGCAGTCCCAGTTATGCATTTCAAGTTTGGGGTTTGTTCT
TTTCGTTAATGTTCCTCTGTGTTGTCAGCTGTCTTCATTTCCTGGGCTAAGCAGCATTGGGAGATGTGGACCAGAGATCCACTCCTTAAG
AACCAGTGGCGAAAGACACTTTCTTTCTTCACTCTGAAGTAGCTGGTGGTACAAATGAGAACTTCAAGAGAGGATGTTATTTAGACTGAA
CCTCTGTTGCCAGAGATGCTGAAGATACAGACCTTGGACAGGTCAGAGGGTTTCATTTTTGGCCTTCATCTTAGATGACTGGTTGCGTCA
TTTGGAGAAGTGAGTGCTCCTTGATGGTGGAATGACCGGGTGGTGGGTACAGAACCATTGTCACAGGGATCCTGGCACAGAGAAGAGTTA
CGAGCAGCAGGGTGCAGGGCTTGGAAGGAATGTGGGCAAGGTTTTGAACTTGATTGTTCTTGAAGCTATCAGACCACATCGAGGCTCAGC
AGTCATCCGTGGGCATTTGGTTTCAACAAAGAAACCTAACATCCTACTCTGGAAACTGATCTCGGAGTTAAGGCGAATTGTTCAAGAACA
CAAACTACATCGCACTCGTCAGTTGTCAGTTCTGGGGCATGACTTTAGCGTTTTGTTTCTGCGAGAACATAACGATCACTCATTTTTATG
TCCCACGTGTGTGTGTCCGCATCTTTCTGGTCAACATTGTTTTAACTAGTCACTCATTAGCGTTTTCAATAGGGCTCTTAAGTCCAGTAG
ATTACGGGTAGTCAGTTGACGAAGATCTGGTTTACAAGAACTAATTAAATGTTTCATTGCATTTTTGTAAGAACAGAATAATTTTATAAA
ATGTTTGTAGTTTATAATTGCCGAAAATAATTTAAAGACACTTTTTTTTTCTCTGTGTGTGCAAATGTGTGTTTGTGATCCATTTTTTTT
TTTTTTTTTTAGGACACCTGTTTACTAGCTAGCTTTACAATATGCCAAAAAAGGATTTCTCCCTGACCCCATCCGTGGTTCACCCTCTTT
TCCCCCCATGCTTTTTGCCCTAGTTTATAACAAAGGAATGATGATGATTTAAAAAGTAGTTCTGTATCTTCAGTATCTTGGTCTTCCAGA
ACCCTCTGGTTGGGAAGGGGATCATTTTTTACTGGTCATTTCCCTTTGGAGTGTAGCTACTTTAACAGATGGAAAGAACCTCATTGGCCA
TGGAAACAGCCGAGGTGTTGGAGCCCAGCAGTGCATGGCACCGTTCGGCATCTGGCTTGATTGGTCTGGCTGCCGTCATTGTCAGCACAG
TGCCATGGACATGGGAAGACTTGACTGCACAGCCAATGGTTTTCATGATGATTACAGCATACACAGTGATCACATAAACGATGACAGCTA
TGGGGCACACAGGCCATTTGCTTACATGCCTCGTATCATGACTGATTACTGCTTTGTTAGAACACAGAAGAGACCCTATTTTATTTAAGG
CAGAACCCCGAAGATACGTATTTCCAATACAGAAAAGAATTTTTAATAAAAACTATAACATACACAAAAATTGGTTTTAAAGTTGACTCC
ACTTCCTCTAACTCCAGTGGATTGTTGGCCATGTCTCCCCAACTCCACAATATCTCTATCATGGGAAACACCTGGGGTTTTTGCGCTACA
TAGGAGAAAGATCTGGAAACTATTTGGGTTTTGTTTTCAACTTTTCATTTGGATGTTTGGCGTTGCACACACACATCCACCGGTGGAAGA
GACGCCCGGTGAAAACACCTGTCTGCTTTCTAAGCCAGTGAGGTTGAGGTGAGAGGTTTGCCAGAGTTTGTCTACCTCTGGGTATCCCTT
TGTCTGGGATAAAAAAAATCAAACCAGAAGGCGGGATGGAATGGATGCACCGCAAATAATGCATTTTCTGAGTTTTCTTGTTAAAAAAAA
ATTTTTTTAAGTAAGAAAAAAAAAGGTAATAACATGGCCAATTTGTTACATAAAATGACTTTCTGTGTATAAATTATTCCTAAAAAATCC
TGTTTATATAAAAAATCAGTAGATGAAAAAAATTTCAAAATGTTTTTGTATATTCTGTTGTAAGAATTTATTCCTGTTATTGCGATATAC
TCTGGATTCTTTACATAATGGAAAAAAGAAACTGTCTATTTTGAATGGCTGAAGCTAAGGCAACGTTAGTTTCTCTTACTCTGCTTTTTT

>53178_53178_3_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000268151_IGF1R_chr15_99434554_ENST00000268035_length(amino acids)=1397AA_BP=243
MSSPACPFQRPRPRSMPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKGYAGNHCETKCVEPLG
LENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLN
GHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNVCPSTCGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPK
VCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWH
RYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTE
VCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYG
SQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNE
ASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGL
LDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRH

--------------------------------------------------------------
>53178_53178_4_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000268151_IGF1R_chr15_99434554_ENST00000558762_length(transcript)=11295nt_BP=747nt
CCAGAACCCCGCGGGGTCTGAGCAGCCCAGCGTGCCCATTCCAGCGCCCGCGTCCCCGCAGCATGCCGCGCCCCCGCCTGCTGGCCGCGC
TGTGCGGCGCGCTGCTCTGCGCCCCCAGCCTCCTCGTCGCCCTGGATATCTGTTCCAAAAACCCCTGCCACAACGGTGGTTTATGCGAGG
AGATTTCCCAAGAAGTGCGAGGAGATGTCTTCCCCTCGTACACCTGCACGTGCCTTAAGGGCTACGCGGGCAACCACTGTGAGACGAAAT
GTGTCGAGCCACTGGGCCTGGAGAATGGGAACATTGCCAACTCACAGATCGCCGCCTCGTCTGTGCGTGTGACCTTCTTGGGTTTGCAGC
ATTGGGTCCCGGAGCTGGCCCGCCTGAACCGCGCAGGCATGGTCAATGCCTGGACACCCAGCAGCAATGACGATAACCCCTGGATCCAGG
TGAACCTGCTGCGGAGGATGTGGGTAACAGGTGTGGTGACGCAGGGTGCCAGCCGCTTGGCCAGTCATGAGTACCTGAAGGCCTTCAAGG
TGGCCTACAGCCTTAATGGACACGAATTCGATTTCATCCATGATGTTAATAAAAAACACAAGGAGTTTGTGGGTAACTGGAACAAAAACG
CGGTGCATGTCAACCTGTTTGAGACCCCTGTGGAGGCTCAGTACGTGAGATTGTACCCCACGAGCTGCCACACGGCCTGCACTCTGCGCT
TTGAGCTACTGGGCTGTGAGCTGAACGTGTGCCCAAGCACGTGTGGGAAGCGGGCGTGCACCGAGAACAATGAGTGCTGCCACCCCGAGT
GCCTGGGCAGCTGCAGCGCGCCTGACAACGACACGGCCTGTGTAGCTTGCCGCCACTACTACTATGCCGGTGTCTGTGTGCCTGCCTGCC
CGCCCAACACCTACAGGTTTGAGGGCTGGCGCTGTGTGGACCGTGACTTCTGCGCCAACATCCTCAGCGCCGAGAGCAGCGACTCCGAGG
GGTTTGTGATCCACGACGGCGAGTGCATGCAGGAGTGCCCCTCGGGCTTCATCCGCAACGGCAGCCAGAGCATGTACTGCATCCCTTGTG
AAGGTCCTTGCCCGAAGGTCTGTGAGGAAGAAAAGAAAACAAAGACCATTGATTCTGTTACTTCTGCTCAGATGCTCCAAGGATGCACCA
TCTTCAAGGGCAATTTGCTCATTAACATCCGACGGGGGAATAACATTGCTTCAGAGCTGGAGAACTTCATGGGGCTCATCGAGGTGGTGA
CGGGCTACGTGAAGATCCGCCATTCTCATGCCTTGGTCTCCTTGTCCTTCCTAAAAAACCTTCGCCTCATCCTAGGAGAGGAGCAGCTAG
AAGGGAATTACTCCTTCTACGTCCTCGACAACCAGAACTTGCAGCAACTGTGGGACTGGGACCACCGCAACCTGACCATCAAAGCAGGGA
AAATGTACTTTGCTTTCAATCCCAAATTATGTGTTTCCGAAATTTACCGCATGGAGGAAGTGACGGGGACTAAAGGGCGCCAAAGCAAAG
GGGACATAAACACCAGGAACAACGGGGAGAGAGCCTCCTGTGAAAGTGACGTCCTGCATTTCACCTCCACCACCACGTCGAAGAATCGCA
TCATCATAACCTGGCACCGGTACCGGCCCCCTGACTACAGGGATCTCATCAGCTTCACCGTTTACTACAAGGAAGCACCCTTTAAGAATG
TCACAGAGTATGATGGGCAGGATGCCTGCGGCTCCAACAGCTGGAACATGGTGGACGTGGACCTCCCGCCCAACAAGGACGTGGAGCCCG
GCATCTTACTACATGGGCTGAAGCCCTGGACTCAGTACGCCGTTTACGTCAAGGCTGTGACCCTCACCATGGTGGAGAACGACCATATCC
GTGGGGCCAAGAGTGAGATCTTGTACATTCGCACCAATGCTTCAGTTCCTTCCATTCCCTTGGACGTTCTTTCAGCATCGAACTCCTCTT
CTCAGTTAATCGTGAAGTGGAACCCTCCCTCTCTGCCCAACGGCAACCTGAGTTACTACATTGTGCGCTGGCAGCGGCAGCCTCAGGACG
GCTACCTTTACCGGCACAATTACTGCTCCAAAGACAAAATCCCCATCAGGAAGTATGCCGACGGCACCATCGACATTGAGGAGGTCACAG
AGAACCCCAAGACTGAGGTGTGTGGTGGGGAGAAAGGGCCTTGCTGCGCCTGCCCCAAAACTGAAGCCGAGAAGCAGGCCGAGAAGGAGG
AGGCTGAATACCGCAAAGTCTTTGAGAATTTCCTGCACAACTCCATCTTCGTGCCCAGACCTGAAAGGAAGCGGAGAGATGTCATGCAAG
TGGCCAACACCACCATGTCCAGCCGAAGCAGGAACACCACGGCCGCAGACACCTACAACATCACCGACCCGGAAGAGCTGGAGACAGAGT
ACCCTTTCTTTGAGAGCAGAGTGGATAACAAGGAGAGAACTGTCATTTCTAACCTTCGGCCTTTCACATTGTACCGCATCGATATCCACA
GCTGCAACCACGAGGCTGAGAAGCTGGGCTGCAGCGCCTCCAACTTCGTCTTTGCAAGGACTATGCCCGCAGAAGGAGCAGATGACATTC
CTGGGCCAGTGACCTGGGAGCCAAGGCCTGAAAACTCCATCTTTTTAAAGTGGCCGGAACCTGAGAATCCCAATGGATTGATTCTAATGT
ATGAAATAAAATACGGATCACAAGTTGAGGATCAGCGAGAATGTGTGTCCAGACAGGAATACAGGAAGTATGGAGGGGCCAAGCTAAACC
GGCTAAACCCGGGGAACTACACAGCCCGGATTCAGGCCACATCTCTCTCTGGGAATGGGTCGTGGACAGATCCTGTGTTCTTCTATGTCC
AGGCCAAAAGATATGAAAACTTCATCCATCTGATCATCGCTCTGCCCGTCGCTGTCCTGTTGATCGTGGGAGGGTTGGTGATTATGCTGT
ACGTCTTCCATAGAAAGAGAAATAACAGCAGGCTGGGGAATGGAGTGCTGTATGCCTCTGTGAACCCGGAGTACTTCAGCGCTGCTGATG
TGTACGTTCCTGATGAGTGGGAGGTGGCTCGGGAGAAGATCACCATGAGCCGGGAACTTGGGCAGGGGTCGTTTGGGATGGTCTATGAAG
GAGTTGCCAAGGGTGTGGTGAAAGATGAACCTGAAACCAGAGTGGCCATTAAAACAGTGAACGAGGCCGCAAGCATGCGTGAGAGGATTG
AGTTTCTCAACGAAGCTTCTGTGATGAAGGAGTTCAATTGTCACCATGTGGTGCGATTGCTGGGTGTGGTGTCCCAAGGCCAGCCAACAC
TGGTCATCATGGAACTGATGACACGGGGCGATCTCAAAAGTTATCTCCGGTCTCTGAGGCCAGAAATGGAGAATAATCCAGTCCTAGCAC
CTCCAAGCCTGAGCAAGATGATTCAGATGGCCGGAGAGATTGCAGACGGCATGGCATACCTCAACGCCAATAAGTTCGTCCACAGAGACC
TTGCTGCCCGGAATTGCATGGTAGCCGAAGATTTCACAGTCAAAATCGGAGATTTTGGTATGACGCGAGATATCTATGAGACAGACTATT
ACCGGAAAGGAGGGAAAGGGCTGCTGCCCGTGCGCTGGATGTCTCCTGAGTCCCTCAAGGATGGAGTCTTCACCACTTACTCGGACGTCT
GGTCCTTCGGGGTCGTCCTCTGGGAGATCGCCACACTGGCCGAGCAGCCCTACCAGGGCTTGTCCAACGAGCAAGTCCTTCGCTTCGTCA
TGGAGGGCGGCCTTCTGGACAAGCCAGACAACTGTCCTGACATGCTGTTTGAACTGATGCGCATGTGCTGGCAGTATAACCCCAAGATGA
GGCCTTCCTTCCTGGAGATCATCAGCAGCATCAAAGAGGAGATGGAGCCTGGCTTCCGGGAGGTCTCCTTCTACTACAGCGAGGAGAACA
AGCTGCCCGAGCCGGAGGAGCTGGACCTGGAGCCAGAGAACATGGAGAGCGTCCCCCTGGACCCCTCGGCCTCCTCGTCCTCCCTGCCAC
TGCCCGACAGACACTCAGGACACAAGGCCGAGAACGGCCCCGGCCCTGGGGTGCTGGTCCTCCGCGCCAGCTTCGACGAGAGACAGCCTT
ACGCCCACATGAACGGGGGCCGCAAGAACGAGCGGGCCTTGCCGCTGCCCCAGTCTTCGACCTGCTGATCCTTGGATCCTGAATCTGTGC
AAACAGTAACGTGTGCGCACGCGCAGCGGGGTGGGGGGGGAGAGAGAGTTTTAACAATCCATTCACAAGCCTCCTGTACCTCAGTGGATC
TTCAGAACTGCCCTTGCTGCCCGCGGGAGACAGCTTCTCTGCAGTAAAACACATTTGGGATGTTCCTTTTTTCAATATGCAAGCAGCTTT
TTATTCCCTGCCCAAACCCTTAACTGACATGGGCCTTTAAGAACCTTAATGACAACACTTAATAGCAACAGAGCACTTGAGAACCAGTCT
CCTCACTCTGTCCCTGTCCTTCCCTGTTCTCCCTTTCTCTCTCCTCTCTGCTTCATAACGGAAAAATAATTGCCACAAGTCCAGCTGGGA
AGCCCTTTTTATCAGTTTGAGGAAGTGGCTGTCCCTGTGGCCCCATCCAACCACTGTACACACCCGCCTGACACCGTGGGTCATTACAAA
AAAACACGTGGAGATGGAAATTTTTACCTTTATCTTTCACCTTTCTAGGGACATGAAATTTACAAAGGGCCATCGTTCATCCAAGGCTGT
TACCATTTTAACGCTGCCTAATTTTGCCAAAATCCTGAACTTTCTCCCTCATCGGCCCGGCGCTGATTCCTCGTGTCCGGAGGCATGGGT
GAGCATGGCAGCTGGTTGCTCCATTTGAGAGACACGCTGGCGACACACTCCGTCCATCCGACTGCCCCTGCTGTGCTGCTCAAGGCCACA
GGCACACAGGTCTCATTGCTTCTGACTAGATTATTATTTGGGGGAACTGGACACAATAGGTCTTTCTCTCAGTGAAGGTGGGGAGAAGCT
GAACCGGCTTCCCTGCCCTGCCTCCCCAGCCCCCTGCCCAACCCCCAAGAATCTGGTGGCCATGGGCCCCGAAGCAGCCTGGCGGACAGG
CTTGGAGTCAAGGGGCCCCATGCCTGCTTCTCTCCCAGCCCCAGCTCCCCCGCCCGCCCCCAAGGACACAGATGGGAAGGGGTTTCCAGG
GACTCAGCCCCACTGTTGATGCAGGTTTGCAAGGAAAGAAATTCAAACACCACAACAGCAGTAAGAAGAAAAGCAGTCAATGGATTCAAG
CATTCTAAGCTTTGTTGACATTTTCTCTGTTCCTAGGACTTCTTCATGGGTCTTACAGTTCTATGTTAGACCATGAAACATTTGCATACA
CATCGTCTTTAATGTCACTTTTATAACTTTTTTACGGTTCAGATATTCATCTATACGTCTGTACAGAAAAAAAAAAGCTGCTATTTTTTT
TGTTCTTGATCTTTGTGGATTTAATCTATGAAAACCTTCAGGTCCACCCTCTCCCCTTTCTGCTCACTCCAAGAAACTTCTTATGCTTTG
TACTAGAGTGCGTGACTTTCTTCCTCTTTTCCCGGTAATGGATACTTCTATCACATAATTTGCCATGAACTGTTGGATGCCTTTTTATAA
ATACATCCCCCATCCCTGCTCCCACCTGCCCCTTTAGTTGTTTTCTAACCCGTAGGCTCTCTGGGCACGAGGCAGAAAGCAGGCCGGGCA
CCCATCCTGAGAGGGCCGCGCTCCTCTCCCCAGCCTGCCCTCACAGCATTGGAGCCTGTTACAGTGCAAGACATGATACAAACTCAGGTC
AGAAAAACAAAGGTTAAATATTTCACACGTCTTTGTTCAGTGTTTCCACTCACCGTGGTTGAGAAGCCTCACCCTCTCTTTCCCTTGCCT
TTGCTTAGGTTGTGACACACATATATATATATTTTTTTAATTCTTGGGTACAACAGCAGTGTTAACCGCAGACACTAGGCATTTGGATTA
CTATTTTTCTTAATGGCTATTTAATCCTTCCATCCCACGAAAAACAGCTGCTGAGTCCAAGGGAGCAGCAGAGCGTGGTCCGGCAGGGCC
TGTTGTGGCCCTCGCCACCCCCCTCACCGGACCGACTGACCTGTCTTTGGAACCAGAACATCCCAAGGGAACTCCTTCGCACTGGCGTTG
AGTGGGACCCCGGGATCCAGGCTGGCCCAGGGCGGCACCCTCAGGGCTGTGCCCGCTGGAGTGCTAGGTGGAGGCAGCACAGACGCCACG
GTGGCCCAAGAGCCCCTTTGCTTCTTGCTGGGGGACCAGGGCTGTGGTGCTGGCCCACTTTCCCTCGGCCAGGAATCCAGGTCCTTGGGG
CCCAGGGGTCTTGTCTTGTTTCATTTTTAGCACTTCTCACCAGAGAGATGACAGCACAAGAGTTGCTTCTGGGATAGAAATGTTTAGGAG
TAAGAACAAAGCTGGGATACGGTGATTGCTAGTTGTGACTGAAGATTCAACACAGAAAAGAAAGTTTATACGGCTTTTTTGCTGGTCAGC
AGTTTGTCCCACTGCTTTCTCTAGTCTCTATCCCATAGCGTGTTCCCTTTAAAAAAAAAAAAAAGGTATTATATGTAGGAGTTTTCTTTT
AATTTATTTTGTGATAAATTACCAGTTTCAATCACTGTAGAAAAGCCCCATTATGAATTTAAATTTCAAGGAAAGGGTGTGTGTGTGTGT
ATGTGTGGGGTGTGTGTGTGTGAGAGTGATGGGACAGTTCTTGATTTTTTGGGTTTTTTTTCCCCCAAACATTTATCTACCTCACTCTTA
TTTTTTATATGTGTATATAGACAAAAGAATACATCTCACCTTTCTCAGCACCTGACAATAGGCCGTTGATACTGGTAACCTCATCCACGC
CACAGGCGCCACACCCAGGTGATGCAGGGGGAAGCCAGGCTGTATTCCGGGGTCAAAGCAACACTAACTCACCTCTCTGCTCATTTCAGA
CAGCTTGCCTTTTTCTGAGATGTCCTGTTTTGTGTTGCTTTTTTTGTTTTGTTTTCTATCTTGGTTTCCACCAAGGTGTTAGATTTCTCC
TCCTCCTAGCCAGGTGGCCCTGTGAGGCCAACGAGGGCACCAGAGCACACCTGGGGGAGCCACCAGGCTGTCCCTGGCTGGTTGTCTTTG
GAACAAACTGCTTCTGTGCAGATGGAATGACCAACACATTTCGTCCTTAAGAGAGCAGTGGTTCCTCAGGTTCTGAGGAGAGGAAGGTGT
CCAGGCAGCACCATCTCTGTGCGAATCCCCAGGGTAAAGGCGTGGGGCATTGGGTTTGCTCCCCTTGCTGCTGCTCCATCCCTGCAGGAG
GCTCGCGCTGAGGCAGGACCGTGCGGCCATGGCTGCTGCATTCATTGAGCACAAAGGTGCAGCTGCAGCAGCAGCTGGAGAGCAAGAGTC
ACCCAGCCTGTGCGCCAGAATGCAGAGGCTCCTGACCTCACAGCCAGTCCCTGATAGAACACACGCAGGAGCAGAGTCCCCTCCCCCTCC
AGGCTGCCCTCTCAACTTCTCCCTCACCTCCTTCCCTAGGGGTAGACAGAGATGTACCAAACCTTCCGGCTGGAAAGCCCAGTGGCCGGC
GCCGAGGCTCGTGGCGTCACGCCCCCCCCGCCAGGGCTGTACCTCCGTCTCCCTGGTCCTGCTGCTCACAGGACAGACGGCTCGCTCCCC
TCTTCCAGCAGCTGCTCTTACAGGCACTGATGATTTCGCTGGGAAGTGTGGCGGGCAGCTTTGCCTAAGCGTGGATGGCTCCTCGGCAAT
TCCAGCCTAAGTGAAGGCGCTCAGGAGCCTCCTGCTGGAACGCGACCCATCTCTCCCAGGACCCCGGGGATCTTAAGGTCATTGAGAAAT
ACTGTTGGATCAGGGTTTTGTTCTTCCACACTGTAGGTGACCCCTTGGAATAACGGCCTCTCCTCTCGTGCACATACCTACCGGTTTCCA
CAACTGGATTTCTACAGATCATTCAGCTGGTTATAAGGGTTTTGTTTAAACTGTCCGAGTTACTGATGTCATTTTGTTTTTGTTTTATGT
AGGTAGCTTTTAAGTAGAAAACACTAACAGTGTAGTGCCCATCATAGCAAATGCTTCAGAAACACCTCAATAAAAGAGAAAACTTGGCTT
GTGTGATGGTGCAGTCACTTTACTGGACCAACCCACCCACCTTGACTATACCAAGGCATCATCTATCCACAGTTCTAGCCTAACTTCATG
CTGATTTCTCTGCCTCTTGATTTTTCTCTGTGTGTTCCAAATAATCTTAAGCTGAGTTGTGGCATTTTCCATGCAACCTCCTTCTGCCAG
CAGCTCACACTGCTTGAAGTCATATGAACCACTGAGGCACATCATGGAATTGATGTGAGCATTAAGACGTTCTCCCACACAGCCCTTCCC
TGAGGCAGCAGGAGCTGGTGTGTACTGGAGACACTGTTGAACTTGATCAAGACCCAGACCACCCCAGGTCTCCTTCGTGGGATGTCATGA
CGTTTGACATACCTTTGGAACGAGCCTCCTCCTTGGAAGATGGAAGACCGTGTTCGTGGCCGACCTGGCCTCTCCTGGCCTGTTTCTTAA
GATGCGGAGTCACATTTCAATGGTACGAAAAGTGGCTTCGTAAAATAGAAGAGCAGTCACTGTGGAACTACCAAATGGCGAGATGCTCGG
TGCACATTGGGGTGCTTTGGGATAAAAGATTTATGAGCCAACTATTCTCTGGCACCAGATTCTAGGCCAGTTTGTTCCACTGAAGCTTTT
CCCACAGCAGTCCACCTCTGCAGGCTGGCAGCCGAATGGCTTGCCAGTGGCTCTGTGGCAAGATCACACTGAGATCGATGGGTGAGAAGG
CTAGGATGCTTGTCTAGTGTTCTTAGCTGTCACGTTGGCTCCTTCCAGGGTGGCCAGACGGTGTTGGCCACTCCCTTCTAAAACACAGGC
GCCCTCCTGGTGACAGTGACCCGCCGTGGTATGCCTTGGCCCATTCCAGCAGTCCCAGTTATGCATTTCAAGTTTGGGGTTTGTTCTTTT
CGTTAATGTTCCTCTGTGTTGTCAGCTGTCTTCATTTCCTGGGCTAAGCAGCATTGGGAGATGTGGACCAGAGATCCACTCCTTAAGAAC
CAGTGGCGAAAGACACTTTCTTTCTTCACTCTGAAGTAGCTGGTGGTACAAATGAGAACTTCAAGAGAGGATGTTATTTAGACTGAACCT
CTGTTGCCAGAGATGCTGAAGATACAGACCTTGGACAGGTCAGAGGGTTTCATTTTTGGCCTTCATCTTAGATGACTGGTTGCGTCATTT
GGAGAAGTGAGTGCTCCTTGATGGTGGAATGACCGGGTGGTGGGTACAGAACCATTGTCACAGGGATCCTGGCACAGAGAAGAGTTACGA
GCAGCAGGGTGCAGGGCTTGGAAGGAATGTGGGCAAGGTTTTGAACTTGATTGTTCTTGAAGCTATCAGACCACATCGAGGCTCAGCAGT
CATCCGTGGGCATTTGGTTTCAACAAAGAAACCTAACATCCTACTCTGGAAACTGATCTCGGAGTTAAGGCGAATTGTTCAAGAACACAA
ACTACATCGCACTCGTCAGTTGTCAGTTCTGGGGCATGACTTTAGCGTTTTGTTTCTGCGAGAACATAACGATCACTCATTTTTATGTCC
CACGTGTGTGTGTCCGCATCTTTCTGGTCAACATTGTTTTAACTAGTCACTCATTAGCGTTTTCAATAGGGCTCTTAAGTCCAGTAGATT
ACGGGTAGTCAGTTGACGAAGATCTGGTTTACAAGAACTAATTAAATGTTTCATTGCATTTTTGTAAGAACAGAATAATTTTATAAAATG
TTTGTAGTTTATAATTGCCGAAAATAATTTAAAGACACTTTTTTTTTCTCTGTGTGTGCAAATGTGTGTTTGTGATCCATTTTTTTTTTT
TTTTTTTAGGACACCTGTTTACTAGCTAGCTTTACAATATGCCAAAAAAGGATTTCTCCCTGACCCCATCCGTGGTTCACCCTCTTTTCC
CCCCATGCTTTTTGCCCTAGTTTATAACAAAGGAATGATGATGATTTAAAAAGTAGTTCTGTATCTTCAGTATCTTGGTCTTCCAGAACC
CTCTGGTTGGGAAGGGGATCATTTTTTACTGGTCATTTCCCTTTGGAGTGTAGCTACTTTAACAGATGGAAAGAACCTCATTGGCCATGG
AAACAGCCGAGGTGTTGGAGCCCAGCAGTGCATGGCACCGTTCGGCATCTGGCTTGATTGGTCTGGCTGCCGTCATTGTCAGCACAGTGC
CATGGACATGGGAAGACTTGACTGCACAGCCAATGGTTTTCATGATGATTACAGCATACACAGTGATCACATAAACGATGACAGCTATGG
GGCACACAGGCCATTTGCTTACATGCCTCGTATCATGACTGATTACTGCTTTGTTAGAACACAGAAGAGACCCTATTTTATTTAAGGCAG
AACCCCGAAGATACGTATTTCCAATACAGAAAAGAATTTTTAATAAAAACTATAACATACACAAAAATTGGTTTTAAAGTTGACTCCACT
TCCTCTAACTCCAGTGGATTGTTGGCCATGTCTCCCCAACTCCACAATATCTCTATCATGGGAAACACCTGGGGTTTTTGCGCTACATAG
GAGAAAGATCTGGAAACTATTTGGGTTTTGTTTTCAACTTTTCATTTGGATGTTTGGCGTTGCACACACACATCCACCGGTGGAAGAGAC
GCCCGGTGAAAACACCTGTCTGCTTTCTAAGCCAGTGAGGTTGAGGTGAGAGGTTTGCCAGAGTTTGTCTACCTCTGGGTATCCCTTTGT
CTGGGATAAAAAAAATCAAACCAGAAGGCGGGATGGAATGGATGCACCGCAAATAATGCATTTTCTGAGTTTTCTTGTTAAAAAAAAATT
TTTTTAAGTAAGAAAAAAAAAGGTAATAACATGGCCAATTTGTTACATAAAATGACTTTCTGTGTATAAATTATTCCTAAAAAATCCTGT
TTATATAAAAAATCAGTAGATGAAAAAAATTTCAAAATGTTTTTGTATATTCTGTTGTAAGAATTTATTCCTGTTATTGCGATATACTCT
GGATTCTTTACATAATGGAAAAAAGAAACTGTCTATTTTGAATGGCTGAAGCTAAGGCAACGTTAGTTTCTCTTACTCTGCTTTTTTCTA

>53178_53178_4_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000268151_IGF1R_chr15_99434554_ENST00000558762_length(amino acids)=1396AA_BP=243
MSSPACPFQRPRPRSMPRPRLLAALCGALLCAPSLLVALDICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKGYAGNHCETKCVEPLG
LENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLN
GHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNVCPSTCGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPK
VCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWH
RYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTE
VCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYG
SQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKRYENFIHLIIALPVAVLLIVGGLVIMLYVFHRK
RNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEA
SVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNC
MVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLL
DKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHS

--------------------------------------------------------------
>53178_53178_5_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000542878_IGF1R_chr15_99434554_ENST00000268035_length(transcript)=11165nt_BP=613nt
AGAACCCCGCGGGGTCTGAGCAGCCCAGCGTGCCCATTCCAGCGCCCGCGTCCCCGCAGCATGCCGCGCCCCCGCCTGCTGGCCGCGCTG
TGCGGCGCGCTGCTCTGCGCCCCCAGCCTCCTCGTCGCCCTGGAATGTGTCGAGCCACTGGGCCTGGAGAATGGGAACATTGCCAACTCA
CAGATCGCCGCCTCGTCTGTGCGTGTGACCTTCTTGGGTTTGCAGCATTGGGTCCCGGAGCTGGCCCGCCTGAACCGCGCAGGCATGGTC
AATGCCTGGACACCCAGCAGCAATGACGATAACCCCTGGATCCAGGTGAACCTGCTGCGGAGGATGTGGGTAACAGGTGTGGTGACGCAG
GGTGCCAGCCGCTTGGCCAGTCATGAGTACCTGAAGGCCTTCAAGGTGGCCTACAGCCTTAATGGACACGAATTCGATTTCATCCATGAT
GTTAATAAAAAACACAAGGAGTTTGTGGGTAACTGGAACAAAAACGCGGTGCATGTCAACCTGTTTGAGACCCCTGTGGAGGCTCAGTAC
GTGAGATTGTACCCCACGAGCTGCCACACGGCCTGCACTCTGCGCTTTGAGCTACTGGGCTGTGAGCTGAACGTGTGCCCAAGCACGTGT
GGGAAGCGGGCGTGCACCGAGAACAATGAGTGCTGCCACCCCGAGTGCCTGGGCAGCTGCAGCGCGCCTGACAACGACACGGCCTGTGTA
GCTTGCCGCCACTACTACTATGCCGGTGTCTGTGTGCCTGCCTGCCCGCCCAACACCTACAGGTTTGAGGGCTGGCGCTGTGTGGACCGT
GACTTCTGCGCCAACATCCTCAGCGCCGAGAGCAGCGACTCCGAGGGGTTTGTGATCCACGACGGCGAGTGCATGCAGGAGTGCCCCTCG
GGCTTCATCCGCAACGGCAGCCAGAGCATGTACTGCATCCCTTGTGAAGGTCCTTGCCCGAAGGTCTGTGAGGAAGAAAAGAAAACAAAG
ACCATTGATTCTGTTACTTCTGCTCAGATGCTCCAAGGATGCACCATCTTCAAGGGCAATTTGCTCATTAACATCCGACGGGGGAATAAC
ATTGCTTCAGAGCTGGAGAACTTCATGGGGCTCATCGAGGTGGTGACGGGCTACGTGAAGATCCGCCATTCTCATGCCTTGGTCTCCTTG
TCCTTCCTAAAAAACCTTCGCCTCATCCTAGGAGAGGAGCAGCTAGAAGGGAATTACTCCTTCTACGTCCTCGACAACCAGAACTTGCAG
CAACTGTGGGACTGGGACCACCGCAACCTGACCATCAAAGCAGGGAAAATGTACTTTGCTTTCAATCCCAAATTATGTGTTTCCGAAATT
TACCGCATGGAGGAAGTGACGGGGACTAAAGGGCGCCAAAGCAAAGGGGACATAAACACCAGGAACAACGGGGAGAGAGCCTCCTGTGAA
AGTGACGTCCTGCATTTCACCTCCACCACCACGTCGAAGAATCGCATCATCATAACCTGGCACCGGTACCGGCCCCCTGACTACAGGGAT
CTCATCAGCTTCACCGTTTACTACAAGGAAGCACCCTTTAAGAATGTCACAGAGTATGATGGGCAGGATGCCTGCGGCTCCAACAGCTGG
AACATGGTGGACGTGGACCTCCCGCCCAACAAGGACGTGGAGCCCGGCATCTTACTACATGGGCTGAAGCCCTGGACTCAGTACGCCGTT
TACGTCAAGGCTGTGACCCTCACCATGGTGGAGAACGACCATATCCGTGGGGCCAAGAGTGAGATCTTGTACATTCGCACCAATGCTTCA
GTTCCTTCCATTCCCTTGGACGTTCTTTCAGCATCGAACTCCTCTTCTCAGTTAATCGTGAAGTGGAACCCTCCCTCTCTGCCCAACGGC
AACCTGAGTTACTACATTGTGCGCTGGCAGCGGCAGCCTCAGGACGGCTACCTTTACCGGCACAATTACTGCTCCAAAGACAAAATCCCC
ATCAGGAAGTATGCCGACGGCACCATCGACATTGAGGAGGTCACAGAGAACCCCAAGACTGAGGTGTGTGGTGGGGAGAAAGGGCCTTGC
TGCGCCTGCCCCAAAACTGAAGCCGAGAAGCAGGCCGAGAAGGAGGAGGCTGAATACCGCAAAGTCTTTGAGAATTTCCTGCACAACTCC
ATCTTCGTGCCCAGACCTGAAAGGAAGCGGAGAGATGTCATGCAAGTGGCCAACACCACCATGTCCAGCCGAAGCAGGAACACCACGGCC
GCAGACACCTACAACATCACCGACCCGGAAGAGCTGGAGACAGAGTACCCTTTCTTTGAGAGCAGAGTGGATAACAAGGAGAGAACTGTC
ATTTCTAACCTTCGGCCTTTCACATTGTACCGCATCGATATCCACAGCTGCAACCACGAGGCTGAGAAGCTGGGCTGCAGCGCCTCCAAC
TTCGTCTTTGCAAGGACTATGCCCGCAGAAGGAGCAGATGACATTCCTGGGCCAGTGACCTGGGAGCCAAGGCCTGAAAACTCCATCTTT
TTAAAGTGGCCGGAACCTGAGAATCCCAATGGATTGATTCTAATGTATGAAATAAAATACGGATCACAAGTTGAGGATCAGCGAGAATGT
GTGTCCAGACAGGAATACAGGAAGTATGGAGGGGCCAAGCTAAACCGGCTAAACCCGGGGAACTACACAGCCCGGATTCAGGCCACATCT
CTCTCTGGGAATGGGTCGTGGACAGATCCTGTGTTCTTCTATGTCCAGGCCAAAACAGGATATGAAAACTTCATCCATCTGATCATCGCT
CTGCCCGTCGCTGTCCTGTTGATCGTGGGAGGGTTGGTGATTATGCTGTACGTCTTCCATAGAAAGAGAAATAACAGCAGGCTGGGGAAT
GGAGTGCTGTATGCCTCTGTGAACCCGGAGTACTTCAGCGCTGCTGATGTGTACGTTCCTGATGAGTGGGAGGTGGCTCGGGAGAAGATC
ACCATGAGCCGGGAACTTGGGCAGGGGTCGTTTGGGATGGTCTATGAAGGAGTTGCCAAGGGTGTGGTGAAAGATGAACCTGAAACCAGA
GTGGCCATTAAAACAGTGAACGAGGCCGCAAGCATGCGTGAGAGGATTGAGTTTCTCAACGAAGCTTCTGTGATGAAGGAGTTCAATTGT
CACCATGTGGTGCGATTGCTGGGTGTGGTGTCCCAAGGCCAGCCAACACTGGTCATCATGGAACTGATGACACGGGGCGATCTCAAAAGT
TATCTCCGGTCTCTGAGGCCAGAAATGGAGAATAATCCAGTCCTAGCACCTCCAAGCCTGAGCAAGATGATTCAGATGGCCGGAGAGATT
GCAGACGGCATGGCATACCTCAACGCCAATAAGTTCGTCCACAGAGACCTTGCTGCCCGGAATTGCATGGTAGCCGAAGATTTCACAGTC
AAAATCGGAGATTTTGGTATGACGCGAGATATCTATGAGACAGACTATTACCGGAAAGGAGGGAAAGGGCTGCTGCCCGTGCGCTGGATG
TCTCCTGAGTCCCTCAAGGATGGAGTCTTCACCACTTACTCGGACGTCTGGTCCTTCGGGGTCGTCCTCTGGGAGATCGCCACACTGGCC
GAGCAGCCCTACCAGGGCTTGTCCAACGAGCAAGTCCTTCGCTTCGTCATGGAGGGCGGCCTTCTGGACAAGCCAGACAACTGTCCTGAC
ATGCTGTTTGAACTGATGCGCATGTGCTGGCAGTATAACCCCAAGATGAGGCCTTCCTTCCTGGAGATCATCAGCAGCATCAAAGAGGAG
ATGGAGCCTGGCTTCCGGGAGGTCTCCTTCTACTACAGCGAGGAGAACAAGCTGCCCGAGCCGGAGGAGCTGGACCTGGAGCCAGAGAAC
ATGGAGAGCGTCCCCCTGGACCCCTCGGCCTCCTCGTCCTCCCTGCCACTGCCCGACAGACACTCAGGACACAAGGCCGAGAACGGCCCC
GGCCCTGGGGTGCTGGTCCTCCGCGCCAGCTTCGACGAGAGACAGCCTTACGCCCACATGAACGGGGGCCGCAAGAACGAGCGGGCCTTG
CCGCTGCCCCAGTCTTCGACCTGCTGATCCTTGGATCCTGAATCTGTGCAAACAGTAACGTGTGCGCACGCGCAGCGGGGTGGGGGGGGA
GAGAGAGTTTTAACAATCCATTCACAAGCCTCCTGTACCTCAGTGGATCTTCAGAACTGCCCTTGCTGCCCGCGGGAGACAGCTTCTCTG
CAGTAAAACACATTTGGGATGTTCCTTTTTTCAATATGCAAGCAGCTTTTTATTCCCTGCCCAAACCCTTAACTGACATGGGCCTTTAAG
AACCTTAATGACAACACTTAATAGCAACAGAGCACTTGAGAACCAGTCTCCTCACTCTGTCCCTGTCCTTCCCTGTTCTCCCTTTCTCTC
TCCTCTCTGCTTCATAACGGAAAAATAATTGCCACAAGTCCAGCTGGGAAGCCCTTTTTATCAGTTTGAGGAAGTGGCTGTCCCTGTGGC
CCCATCCAACCACTGTACACACCCGCCTGACACCGTGGGTCATTACAAAAAAACACGTGGAGATGGAAATTTTTACCTTTATCTTTCACC
TTTCTAGGGACATGAAATTTACAAAGGGCCATCGTTCATCCAAGGCTGTTACCATTTTAACGCTGCCTAATTTTGCCAAAATCCTGAACT
TTCTCCCTCATCGGCCCGGCGCTGATTCCTCGTGTCCGGAGGCATGGGTGAGCATGGCAGCTGGTTGCTCCATTTGAGAGACACGCTGGC
GACACACTCCGTCCATCCGACTGCCCCTGCTGTGCTGCTCAAGGCCACAGGCACACAGGTCTCATTGCTTCTGACTAGATTATTATTTGG
GGGAACTGGACACAATAGGTCTTTCTCTCAGTGAAGGTGGGGAGAAGCTGAACCGGCTTCCCTGCCCTGCCTCCCCAGCCCCCTGCCCAA
CCCCCAAGAATCTGGTGGCCATGGGCCCCGAAGCAGCCTGGCGGACAGGCTTGGAGTCAAGGGGCCCCATGCCTGCTTCTCTCCCAGCCC
CAGCTCCCCCGCCCGCCCCCAAGGACACAGATGGGAAGGGGTTTCCAGGGACTCAGCCCCACTGTTGATGCAGGTTTGCAAGGAAAGAAA
TTCAAACACCACAACAGCAGTAAGAAGAAAAGCAGTCAATGGATTCAAGCATTCTAAGCTTTGTTGACATTTTCTCTGTTCCTAGGACTT
CTTCATGGGTCTTACAGTTCTATGTTAGACCATGAAACATTTGCATACACATCGTCTTTAATGTCACTTTTATAACTTTTTTACGGTTCA
GATATTCATCTATACGTCTGTACAGAAAAAAAAAAGCTGCTATTTTTTTTGTTCTTGATCTTTGTGGATTTAATCTATGAAAACCTTCAG
GTCCACCCTCTCCCCTTTCTGCTCACTCCAAGAAACTTCTTATGCTTTGTACTAGAGTGCGTGACTTTCTTCCTCTTTTCCCGGTAATGG
ATACTTCTATCACATAATTTGCCATGAACTGTTGGATGCCTTTTTATAAATACATCCCCCATCCCTGCTCCCACCTGCCCCTTTAGTTGT
TTTCTAACCCGTAGGCTCTCTGGGCACGAGGCAGAAAGCAGGCCGGGCACCCATCCTGAGAGGGCCGCGCTCCTCTCCCCAGCCTGCCCT
CACAGCATTGGAGCCTGTTACAGTGCAAGACATGATACAAACTCAGGTCAGAAAAACAAAGGTTAAATATTTCACACGTCTTTGTTCAGT
GTTTCCACTCACCGTGGTTGAGAAGCCTCACCCTCTCTTTCCCTTGCCTTTGCTTAGGTTGTGACACACATATATATATATTTTTTTAAT
TCTTGGGTACAACAGCAGTGTTAACCGCAGACACTAGGCATTTGGATTACTATTTTTCTTAATGGCTATTTAATCCTTCCATCCCACGAA
AAACAGCTGCTGAGTCCAAGGGAGCAGCAGAGCGTGGTCCGGCAGGGCCTGTTGTGGCCCTCGCCACCCCCCTCACCGGACCGACTGACC
TGTCTTTGGAACCAGAACATCCCAAGGGAACTCCTTCGCACTGGCGTTGAGTGGGACCCCGGGATCCAGGCTGGCCCAGGGCGGCACCCT
CAGGGCTGTGCCCGCTGGAGTGCTAGGTGGAGGCAGCACAGACGCCACGGTGGCCCAAGAGCCCCTTTGCTTCTTGCTGGGGGACCAGGG
CTGTGGTGCTGGCCCACTTTCCCTCGGCCAGGAATCCAGGTCCTTGGGGCCCAGGGGTCTTGTCTTGTTTCATTTTTAGCACTTCTCACC
AGAGAGATGACAGCACAAGAGTTGCTTCTGGGATAGAAATGTTTAGGAGTAAGAACAAAGCTGGGATACGGTGATTGCTAGTTGTGACTG
AAGATTCAACACAGAAAAGAAAGTTTATACGGCTTTTTTGCTGGTCAGCAGTTTGTCCCACTGCTTTCTCTAGTCTCTATCCCATAGCGT
GTTCCCTTTAAAAAAAAAAAAAAGGTATTATATGTAGGAGTTTTCTTTTAATTTATTTTGTGATAAATTACCAGTTTCAATCACTGTAGA
AAAGCCCCATTATGAATTTAAATTTCAAGGAAAGGGTGTGTGTGTGTGTATGTGTGGGGTGTGTGTGTGTGAGAGTGATGGGACAGTTCT
TGATTTTTTGGGTTTTTTTTCCCCCAAACATTTATCTACCTCACTCTTATTTTTTATATGTGTATATAGACAAAAGAATACATCTCACCT
TTCTCAGCACCTGACAATAGGCCGTTGATACTGGTAACCTCATCCACGCCACAGGCGCCACACCCAGGTGATGCAGGGGGAAGCCAGGCT
GTATTCCGGGGTCAAAGCAACACTAACTCACCTCTCTGCTCATTTCAGACAGCTTGCCTTTTTCTGAGATGTCCTGTTTTGTGTTGCTTT
TTTTGTTTTGTTTTCTATCTTGGTTTCCACCAAGGTGTTAGATTTCTCCTCCTCCTAGCCAGGTGGCCCTGTGAGGCCAACGAGGGCACC
AGAGCACACCTGGGGGAGCCACCAGGCTGTCCCTGGCTGGTTGTCTTTGGAACAAACTGCTTCTGTGCAGATGGAATGACCAACACATTT
CGTCCTTAAGAGAGCAGTGGTTCCTCAGGTTCTGAGGAGAGGAAGGTGTCCAGGCAGCACCATCTCTGTGCGAATCCCCAGGGTAAAGGC
GTGGGGCATTGGGTTTGCTCCCCTTGCTGCTGCTCCATCCCTGCAGGAGGCTCGCGCTGAGGCAGGACCGTGCGGCCATGGCTGCTGCAT
TCATTGAGCACAAAGGTGCAGCTGCAGCAGCAGCTGGAGAGCAAGAGTCACCCAGCCTGTGCGCCAGAATGCAGAGGCTCCTGACCTCAC
AGCCAGTCCCTGATAGAACACACGCAGGAGCAGAGTCCCCTCCCCCTCCAGGCTGCCCTCTCAACTTCTCCCTCACCTCCTTCCCTAGGG
GTAGACAGAGATGTACCAAACCTTCCGGCTGGAAAGCCCAGTGGCCGGCGCCGAGGCTCGTGGCGTCACGCCCCCCCCGCCAGGGCTGTA
CCTCCGTCTCCCTGGTCCTGCTGCTCACAGGACAGACGGCTCGCTCCCCTCTTCCAGCAGCTGCTCTTACAGGCACTGATGATTTCGCTG
GGAAGTGTGGCGGGCAGCTTTGCCTAAGCGTGGATGGCTCCTCGGCAATTCCAGCCTAAGTGAAGGCGCTCAGGAGCCTCCTGCTGGAAC
GCGACCCATCTCTCCCAGGACCCCGGGGATCTTAAGGTCATTGAGAAATACTGTTGGATCAGGGTTTTGTTCTTCCACACTGTAGGTGAC
CCCTTGGAATAACGGCCTCTCCTCTCGTGCACATACCTACCGGTTTCCACAACTGGATTTCTACAGATCATTCAGCTGGTTATAAGGGTT
TTGTTTAAACTGTCCGAGTTACTGATGTCATTTTGTTTTTGTTTTATGTAGGTAGCTTTTAAGTAGAAAACACTAACAGTGTAGTGCCCA
TCATAGCAAATGCTTCAGAAACACCTCAATAAAAGAGAAAACTTGGCTTGTGTGATGGTGCAGTCACTTTACTGGACCAACCCACCCACC
TTGACTATACCAAGGCATCATCTATCCACAGTTCTAGCCTAACTTCATGCTGATTTCTCTGCCTCTTGATTTTTCTCTGTGTGTTCCAAA
TAATCTTAAGCTGAGTTGTGGCATTTTCCATGCAACCTCCTTCTGCCAGCAGCTCACACTGCTTGAAGTCATATGAACCACTGAGGCACA
TCATGGAATTGATGTGAGCATTAAGACGTTCTCCCACACAGCCCTTCCCTGAGGCAGCAGGAGCTGGTGTGTACTGGAGACACTGTTGAA
CTTGATCAAGACCCAGACCACCCCAGGTCTCCTTCGTGGGATGTCATGACGTTTGACATACCTTTGGAACGAGCCTCCTCCTTGGAAGAT
GGAAGACCGTGTTCGTGGCCGACCTGGCCTCTCCTGGCCTGTTTCTTAAGATGCGGAGTCACATTTCAATGGTACGAAAAGTGGCTTCGT
AAAATAGAAGAGCAGTCACTGTGGAACTACCAAATGGCGAGATGCTCGGTGCACATTGGGGTGCTTTGGGATAAAAGATTTATGAGCCAA
CTATTCTCTGGCACCAGATTCTAGGCCAGTTTGTTCCACTGAAGCTTTTCCCACAGCAGTCCACCTCTGCAGGCTGGCAGCCGAATGGCT
TGCCAGTGGCTCTGTGGCAAGATCACACTGAGATCGATGGGTGAGAAGGCTAGGATGCTTGTCTAGTGTTCTTAGCTGTCACGTTGGCTC
CTTCCAGGGTGGCCAGACGGTGTTGGCCACTCCCTTCTAAAACACAGGCGCCCTCCTGGTGACAGTGACCCGCCGTGGTATGCCTTGGCC
CATTCCAGCAGTCCCAGTTATGCATTTCAAGTTTGGGGTTTGTTCTTTTCGTTAATGTTCCTCTGTGTTGTCAGCTGTCTTCATTTCCTG
GGCTAAGCAGCATTGGGAGATGTGGACCAGAGATCCACTCCTTAAGAACCAGTGGCGAAAGACACTTTCTTTCTTCACTCTGAAGTAGCT
GGTGGTACAAATGAGAACTTCAAGAGAGGATGTTATTTAGACTGAACCTCTGTTGCCAGAGATGCTGAAGATACAGACCTTGGACAGGTC
AGAGGGTTTCATTTTTGGCCTTCATCTTAGATGACTGGTTGCGTCATTTGGAGAAGTGAGTGCTCCTTGATGGTGGAATGACCGGGTGGT
GGGTACAGAACCATTGTCACAGGGATCCTGGCACAGAGAAGAGTTACGAGCAGCAGGGTGCAGGGCTTGGAAGGAATGTGGGCAAGGTTT
TGAACTTGATTGTTCTTGAAGCTATCAGACCACATCGAGGCTCAGCAGTCATCCGTGGGCATTTGGTTTCAACAAAGAAACCTAACATCC
TACTCTGGAAACTGATCTCGGAGTTAAGGCGAATTGTTCAAGAACACAAACTACATCGCACTCGTCAGTTGTCAGTTCTGGGGCATGACT
TTAGCGTTTTGTTTCTGCGAGAACATAACGATCACTCATTTTTATGTCCCACGTGTGTGTGTCCGCATCTTTCTGGTCAACATTGTTTTA
ACTAGTCACTCATTAGCGTTTTCAATAGGGCTCTTAAGTCCAGTAGATTACGGGTAGTCAGTTGACGAAGATCTGGTTTACAAGAACTAA
TTAAATGTTTCATTGCATTTTTGTAAGAACAGAATAATTTTATAAAATGTTTGTAGTTTATAATTGCCGAAAATAATTTAAAGACACTTT
TTTTTTCTCTGTGTGTGCAAATGTGTGTTTGTGATCCATTTTTTTTTTTTTTTTTTAGGACACCTGTTTACTAGCTAGCTTTACAATATG
CCAAAAAAGGATTTCTCCCTGACCCCATCCGTGGTTCACCCTCTTTTCCCCCCATGCTTTTTGCCCTAGTTTATAACAAAGGAATGATGA
TGATTTAAAAAGTAGTTCTGTATCTTCAGTATCTTGGTCTTCCAGAACCCTCTGGTTGGGAAGGGGATCATTTTTTACTGGTCATTTCCC
TTTGGAGTGTAGCTACTTTAACAGATGGAAAGAACCTCATTGGCCATGGAAACAGCCGAGGTGTTGGAGCCCAGCAGTGCATGGCACCGT
TCGGCATCTGGCTTGATTGGTCTGGCTGCCGTCATTGTCAGCACAGTGCCATGGACATGGGAAGACTTGACTGCACAGCCAATGGTTTTC
ATGATGATTACAGCATACACAGTGATCACATAAACGATGACAGCTATGGGGCACACAGGCCATTTGCTTACATGCCTCGTATCATGACTG
ATTACTGCTTTGTTAGAACACAGAAGAGACCCTATTTTATTTAAGGCAGAACCCCGAAGATACGTATTTCCAATACAGAAAAGAATTTTT
AATAAAAACTATAACATACACAAAAATTGGTTTTAAAGTTGACTCCACTTCCTCTAACTCCAGTGGATTGTTGGCCATGTCTCCCCAACT
CCACAATATCTCTATCATGGGAAACACCTGGGGTTTTTGCGCTACATAGGAGAAAGATCTGGAAACTATTTGGGTTTTGTTTTCAACTTT
TCATTTGGATGTTTGGCGTTGCACACACACATCCACCGGTGGAAGAGACGCCCGGTGAAAACACCTGTCTGCTTTCTAAGCCAGTGAGGT
TGAGGTGAGAGGTTTGCCAGAGTTTGTCTACCTCTGGGTATCCCTTTGTCTGGGATAAAAAAAATCAAACCAGAAGGCGGGATGGAATGG
ATGCACCGCAAATAATGCATTTTCTGAGTTTTCTTGTTAAAAAAAAATTTTTTTAAGTAAGAAAAAAAAAGGTAATAACATGGCCAATTT
GTTACATAAAATGACTTTCTGTGTATAAATTATTCCTAAAAAATCCTGTTTATATAAAAAATCAGTAGATGAAAAAAATTTCAAAATGTT
TTTGTATATTCTGTTGTAAGAATTTATTCCTGTTATTGCGATATACTCTGGATTCTTTACATAATGGAAAAAAGAAACTGTCTATTTTGA
ATGGCTGAAGCTAAGGCAACGTTAGTTTCTCTTACTCTGCTTTTTTCTAGTAAAGTACTACATGGTTTAAGTTAAATAAAATAATTCTGT

>53178_53178_5_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000542878_IGF1R_chr15_99434554_ENST00000268035_length(amino acids)=1353AA_BP=199
MSSPACPFQRPRPRSMPRPRLLAALCGALLCAPSLLVALECVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTP
SSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYP
TSCHTACTLRFELLGCELNVCPSTCGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCAN
ILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASEL
ENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEE
VTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDV
DLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYY
IVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPR
PERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFAR
TMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNG
SWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRE
LGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSL
RPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESL
KDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGF
REVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQS

--------------------------------------------------------------
>53178_53178_6_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000542878_IGF1R_chr15_99434554_ENST00000558762_length(transcript)=11161nt_BP=613nt
AGAACCCCGCGGGGTCTGAGCAGCCCAGCGTGCCCATTCCAGCGCCCGCGTCCCCGCAGCATGCCGCGCCCCCGCCTGCTGGCCGCGCTG
TGCGGCGCGCTGCTCTGCGCCCCCAGCCTCCTCGTCGCCCTGGAATGTGTCGAGCCACTGGGCCTGGAGAATGGGAACATTGCCAACTCA
CAGATCGCCGCCTCGTCTGTGCGTGTGACCTTCTTGGGTTTGCAGCATTGGGTCCCGGAGCTGGCCCGCCTGAACCGCGCAGGCATGGTC
AATGCCTGGACACCCAGCAGCAATGACGATAACCCCTGGATCCAGGTGAACCTGCTGCGGAGGATGTGGGTAACAGGTGTGGTGACGCAG
GGTGCCAGCCGCTTGGCCAGTCATGAGTACCTGAAGGCCTTCAAGGTGGCCTACAGCCTTAATGGACACGAATTCGATTTCATCCATGAT
GTTAATAAAAAACACAAGGAGTTTGTGGGTAACTGGAACAAAAACGCGGTGCATGTCAACCTGTTTGAGACCCCTGTGGAGGCTCAGTAC
GTGAGATTGTACCCCACGAGCTGCCACACGGCCTGCACTCTGCGCTTTGAGCTACTGGGCTGTGAGCTGAACGTGTGCCCAAGCACGTGT
GGGAAGCGGGCGTGCACCGAGAACAATGAGTGCTGCCACCCCGAGTGCCTGGGCAGCTGCAGCGCGCCTGACAACGACACGGCCTGTGTA
GCTTGCCGCCACTACTACTATGCCGGTGTCTGTGTGCCTGCCTGCCCGCCCAACACCTACAGGTTTGAGGGCTGGCGCTGTGTGGACCGT
GACTTCTGCGCCAACATCCTCAGCGCCGAGAGCAGCGACTCCGAGGGGTTTGTGATCCACGACGGCGAGTGCATGCAGGAGTGCCCCTCG
GGCTTCATCCGCAACGGCAGCCAGAGCATGTACTGCATCCCTTGTGAAGGTCCTTGCCCGAAGGTCTGTGAGGAAGAAAAGAAAACAAAG
ACCATTGATTCTGTTACTTCTGCTCAGATGCTCCAAGGATGCACCATCTTCAAGGGCAATTTGCTCATTAACATCCGACGGGGGAATAAC
ATTGCTTCAGAGCTGGAGAACTTCATGGGGCTCATCGAGGTGGTGACGGGCTACGTGAAGATCCGCCATTCTCATGCCTTGGTCTCCTTG
TCCTTCCTAAAAAACCTTCGCCTCATCCTAGGAGAGGAGCAGCTAGAAGGGAATTACTCCTTCTACGTCCTCGACAACCAGAACTTGCAG
CAACTGTGGGACTGGGACCACCGCAACCTGACCATCAAAGCAGGGAAAATGTACTTTGCTTTCAATCCCAAATTATGTGTTTCCGAAATT
TACCGCATGGAGGAAGTGACGGGGACTAAAGGGCGCCAAAGCAAAGGGGACATAAACACCAGGAACAACGGGGAGAGAGCCTCCTGTGAA
AGTGACGTCCTGCATTTCACCTCCACCACCACGTCGAAGAATCGCATCATCATAACCTGGCACCGGTACCGGCCCCCTGACTACAGGGAT
CTCATCAGCTTCACCGTTTACTACAAGGAAGCACCCTTTAAGAATGTCACAGAGTATGATGGGCAGGATGCCTGCGGCTCCAACAGCTGG
AACATGGTGGACGTGGACCTCCCGCCCAACAAGGACGTGGAGCCCGGCATCTTACTACATGGGCTGAAGCCCTGGACTCAGTACGCCGTT
TACGTCAAGGCTGTGACCCTCACCATGGTGGAGAACGACCATATCCGTGGGGCCAAGAGTGAGATCTTGTACATTCGCACCAATGCTTCA
GTTCCTTCCATTCCCTTGGACGTTCTTTCAGCATCGAACTCCTCTTCTCAGTTAATCGTGAAGTGGAACCCTCCCTCTCTGCCCAACGGC
AACCTGAGTTACTACATTGTGCGCTGGCAGCGGCAGCCTCAGGACGGCTACCTTTACCGGCACAATTACTGCTCCAAAGACAAAATCCCC
ATCAGGAAGTATGCCGACGGCACCATCGACATTGAGGAGGTCACAGAGAACCCCAAGACTGAGGTGTGTGGTGGGGAGAAAGGGCCTTGC
TGCGCCTGCCCCAAAACTGAAGCCGAGAAGCAGGCCGAGAAGGAGGAGGCTGAATACCGCAAAGTCTTTGAGAATTTCCTGCACAACTCC
ATCTTCGTGCCCAGACCTGAAAGGAAGCGGAGAGATGTCATGCAAGTGGCCAACACCACCATGTCCAGCCGAAGCAGGAACACCACGGCC
GCAGACACCTACAACATCACCGACCCGGAAGAGCTGGAGACAGAGTACCCTTTCTTTGAGAGCAGAGTGGATAACAAGGAGAGAACTGTC
ATTTCTAACCTTCGGCCTTTCACATTGTACCGCATCGATATCCACAGCTGCAACCACGAGGCTGAGAAGCTGGGCTGCAGCGCCTCCAAC
TTCGTCTTTGCAAGGACTATGCCCGCAGAAGGAGCAGATGACATTCCTGGGCCAGTGACCTGGGAGCCAAGGCCTGAAAACTCCATCTTT
TTAAAGTGGCCGGAACCTGAGAATCCCAATGGATTGATTCTAATGTATGAAATAAAATACGGATCACAAGTTGAGGATCAGCGAGAATGT
GTGTCCAGACAGGAATACAGGAAGTATGGAGGGGCCAAGCTAAACCGGCTAAACCCGGGGAACTACACAGCCCGGATTCAGGCCACATCT
CTCTCTGGGAATGGGTCGTGGACAGATCCTGTGTTCTTCTATGTCCAGGCCAAAAGATATGAAAACTTCATCCATCTGATCATCGCTCTG
CCCGTCGCTGTCCTGTTGATCGTGGGAGGGTTGGTGATTATGCTGTACGTCTTCCATAGAAAGAGAAATAACAGCAGGCTGGGGAATGGA
GTGCTGTATGCCTCTGTGAACCCGGAGTACTTCAGCGCTGCTGATGTGTACGTTCCTGATGAGTGGGAGGTGGCTCGGGAGAAGATCACC
ATGAGCCGGGAACTTGGGCAGGGGTCGTTTGGGATGGTCTATGAAGGAGTTGCCAAGGGTGTGGTGAAAGATGAACCTGAAACCAGAGTG
GCCATTAAAACAGTGAACGAGGCCGCAAGCATGCGTGAGAGGATTGAGTTTCTCAACGAAGCTTCTGTGATGAAGGAGTTCAATTGTCAC
CATGTGGTGCGATTGCTGGGTGTGGTGTCCCAAGGCCAGCCAACACTGGTCATCATGGAACTGATGACACGGGGCGATCTCAAAAGTTAT
CTCCGGTCTCTGAGGCCAGAAATGGAGAATAATCCAGTCCTAGCACCTCCAAGCCTGAGCAAGATGATTCAGATGGCCGGAGAGATTGCA
GACGGCATGGCATACCTCAACGCCAATAAGTTCGTCCACAGAGACCTTGCTGCCCGGAATTGCATGGTAGCCGAAGATTTCACAGTCAAA
ATCGGAGATTTTGGTATGACGCGAGATATCTATGAGACAGACTATTACCGGAAAGGAGGGAAAGGGCTGCTGCCCGTGCGCTGGATGTCT
CCTGAGTCCCTCAAGGATGGAGTCTTCACCACTTACTCGGACGTCTGGTCCTTCGGGGTCGTCCTCTGGGAGATCGCCACACTGGCCGAG
CAGCCCTACCAGGGCTTGTCCAACGAGCAAGTCCTTCGCTTCGTCATGGAGGGCGGCCTTCTGGACAAGCCAGACAACTGTCCTGACATG
CTGTTTGAACTGATGCGCATGTGCTGGCAGTATAACCCCAAGATGAGGCCTTCCTTCCTGGAGATCATCAGCAGCATCAAAGAGGAGATG
GAGCCTGGCTTCCGGGAGGTCTCCTTCTACTACAGCGAGGAGAACAAGCTGCCCGAGCCGGAGGAGCTGGACCTGGAGCCAGAGAACATG
GAGAGCGTCCCCCTGGACCCCTCGGCCTCCTCGTCCTCCCTGCCACTGCCCGACAGACACTCAGGACACAAGGCCGAGAACGGCCCCGGC
CCTGGGGTGCTGGTCCTCCGCGCCAGCTTCGACGAGAGACAGCCTTACGCCCACATGAACGGGGGCCGCAAGAACGAGCGGGCCTTGCCG
CTGCCCCAGTCTTCGACCTGCTGATCCTTGGATCCTGAATCTGTGCAAACAGTAACGTGTGCGCACGCGCAGCGGGGTGGGGGGGGAGAG
AGAGTTTTAACAATCCATTCACAAGCCTCCTGTACCTCAGTGGATCTTCAGAACTGCCCTTGCTGCCCGCGGGAGACAGCTTCTCTGCAG
TAAAACACATTTGGGATGTTCCTTTTTTCAATATGCAAGCAGCTTTTTATTCCCTGCCCAAACCCTTAACTGACATGGGCCTTTAAGAAC
CTTAATGACAACACTTAATAGCAACAGAGCACTTGAGAACCAGTCTCCTCACTCTGTCCCTGTCCTTCCCTGTTCTCCCTTTCTCTCTCC
TCTCTGCTTCATAACGGAAAAATAATTGCCACAAGTCCAGCTGGGAAGCCCTTTTTATCAGTTTGAGGAAGTGGCTGTCCCTGTGGCCCC
ATCCAACCACTGTACACACCCGCCTGACACCGTGGGTCATTACAAAAAAACACGTGGAGATGGAAATTTTTACCTTTATCTTTCACCTTT
CTAGGGACATGAAATTTACAAAGGGCCATCGTTCATCCAAGGCTGTTACCATTTTAACGCTGCCTAATTTTGCCAAAATCCTGAACTTTC
TCCCTCATCGGCCCGGCGCTGATTCCTCGTGTCCGGAGGCATGGGTGAGCATGGCAGCTGGTTGCTCCATTTGAGAGACACGCTGGCGAC
ACACTCCGTCCATCCGACTGCCCCTGCTGTGCTGCTCAAGGCCACAGGCACACAGGTCTCATTGCTTCTGACTAGATTATTATTTGGGGG
AACTGGACACAATAGGTCTTTCTCTCAGTGAAGGTGGGGAGAAGCTGAACCGGCTTCCCTGCCCTGCCTCCCCAGCCCCCTGCCCAACCC
CCAAGAATCTGGTGGCCATGGGCCCCGAAGCAGCCTGGCGGACAGGCTTGGAGTCAAGGGGCCCCATGCCTGCTTCTCTCCCAGCCCCAG
CTCCCCCGCCCGCCCCCAAGGACACAGATGGGAAGGGGTTTCCAGGGACTCAGCCCCACTGTTGATGCAGGTTTGCAAGGAAAGAAATTC
AAACACCACAACAGCAGTAAGAAGAAAAGCAGTCAATGGATTCAAGCATTCTAAGCTTTGTTGACATTTTCTCTGTTCCTAGGACTTCTT
CATGGGTCTTACAGTTCTATGTTAGACCATGAAACATTTGCATACACATCGTCTTTAATGTCACTTTTATAACTTTTTTACGGTTCAGAT
ATTCATCTATACGTCTGTACAGAAAAAAAAAAGCTGCTATTTTTTTTGTTCTTGATCTTTGTGGATTTAATCTATGAAAACCTTCAGGTC
CACCCTCTCCCCTTTCTGCTCACTCCAAGAAACTTCTTATGCTTTGTACTAGAGTGCGTGACTTTCTTCCTCTTTTCCCGGTAATGGATA
CTTCTATCACATAATTTGCCATGAACTGTTGGATGCCTTTTTATAAATACATCCCCCATCCCTGCTCCCACCTGCCCCTTTAGTTGTTTT
CTAACCCGTAGGCTCTCTGGGCACGAGGCAGAAAGCAGGCCGGGCACCCATCCTGAGAGGGCCGCGCTCCTCTCCCCAGCCTGCCCTCAC
AGCATTGGAGCCTGTTACAGTGCAAGACATGATACAAACTCAGGTCAGAAAAACAAAGGTTAAATATTTCACACGTCTTTGTTCAGTGTT
TCCACTCACCGTGGTTGAGAAGCCTCACCCTCTCTTTCCCTTGCCTTTGCTTAGGTTGTGACACACATATATATATATTTTTTTAATTCT
TGGGTACAACAGCAGTGTTAACCGCAGACACTAGGCATTTGGATTACTATTTTTCTTAATGGCTATTTAATCCTTCCATCCCACGAAAAA
CAGCTGCTGAGTCCAAGGGAGCAGCAGAGCGTGGTCCGGCAGGGCCTGTTGTGGCCCTCGCCACCCCCCTCACCGGACCGACTGACCTGT
CTTTGGAACCAGAACATCCCAAGGGAACTCCTTCGCACTGGCGTTGAGTGGGACCCCGGGATCCAGGCTGGCCCAGGGCGGCACCCTCAG
GGCTGTGCCCGCTGGAGTGCTAGGTGGAGGCAGCACAGACGCCACGGTGGCCCAAGAGCCCCTTTGCTTCTTGCTGGGGGACCAGGGCTG
TGGTGCTGGCCCACTTTCCCTCGGCCAGGAATCCAGGTCCTTGGGGCCCAGGGGTCTTGTCTTGTTTCATTTTTAGCACTTCTCACCAGA
GAGATGACAGCACAAGAGTTGCTTCTGGGATAGAAATGTTTAGGAGTAAGAACAAAGCTGGGATACGGTGATTGCTAGTTGTGACTGAAG
ATTCAACACAGAAAAGAAAGTTTATACGGCTTTTTTGCTGGTCAGCAGTTTGTCCCACTGCTTTCTCTAGTCTCTATCCCATAGCGTGTT
CCCTTTAAAAAAAAAAAAAAGGTATTATATGTAGGAGTTTTCTTTTAATTTATTTTGTGATAAATTACCAGTTTCAATCACTGTAGAAAA
GCCCCATTATGAATTTAAATTTCAAGGAAAGGGTGTGTGTGTGTGTATGTGTGGGGTGTGTGTGTGTGAGAGTGATGGGACAGTTCTTGA
TTTTTTGGGTTTTTTTTCCCCCAAACATTTATCTACCTCACTCTTATTTTTTATATGTGTATATAGACAAAAGAATACATCTCACCTTTC
TCAGCACCTGACAATAGGCCGTTGATACTGGTAACCTCATCCACGCCACAGGCGCCACACCCAGGTGATGCAGGGGGAAGCCAGGCTGTA
TTCCGGGGTCAAAGCAACACTAACTCACCTCTCTGCTCATTTCAGACAGCTTGCCTTTTTCTGAGATGTCCTGTTTTGTGTTGCTTTTTT
TGTTTTGTTTTCTATCTTGGTTTCCACCAAGGTGTTAGATTTCTCCTCCTCCTAGCCAGGTGGCCCTGTGAGGCCAACGAGGGCACCAGA
GCACACCTGGGGGAGCCACCAGGCTGTCCCTGGCTGGTTGTCTTTGGAACAAACTGCTTCTGTGCAGATGGAATGACCAACACATTTCGT
CCTTAAGAGAGCAGTGGTTCCTCAGGTTCTGAGGAGAGGAAGGTGTCCAGGCAGCACCATCTCTGTGCGAATCCCCAGGGTAAAGGCGTG
GGGCATTGGGTTTGCTCCCCTTGCTGCTGCTCCATCCCTGCAGGAGGCTCGCGCTGAGGCAGGACCGTGCGGCCATGGCTGCTGCATTCA
TTGAGCACAAAGGTGCAGCTGCAGCAGCAGCTGGAGAGCAAGAGTCACCCAGCCTGTGCGCCAGAATGCAGAGGCTCCTGACCTCACAGC
CAGTCCCTGATAGAACACACGCAGGAGCAGAGTCCCCTCCCCCTCCAGGCTGCCCTCTCAACTTCTCCCTCACCTCCTTCCCTAGGGGTA
GACAGAGATGTACCAAACCTTCCGGCTGGAAAGCCCAGTGGCCGGCGCCGAGGCTCGTGGCGTCACGCCCCCCCCGCCAGGGCTGTACCT
CCGTCTCCCTGGTCCTGCTGCTCACAGGACAGACGGCTCGCTCCCCTCTTCCAGCAGCTGCTCTTACAGGCACTGATGATTTCGCTGGGA
AGTGTGGCGGGCAGCTTTGCCTAAGCGTGGATGGCTCCTCGGCAATTCCAGCCTAAGTGAAGGCGCTCAGGAGCCTCCTGCTGGAACGCG
ACCCATCTCTCCCAGGACCCCGGGGATCTTAAGGTCATTGAGAAATACTGTTGGATCAGGGTTTTGTTCTTCCACACTGTAGGTGACCCC
TTGGAATAACGGCCTCTCCTCTCGTGCACATACCTACCGGTTTCCACAACTGGATTTCTACAGATCATTCAGCTGGTTATAAGGGTTTTG
TTTAAACTGTCCGAGTTACTGATGTCATTTTGTTTTTGTTTTATGTAGGTAGCTTTTAAGTAGAAAACACTAACAGTGTAGTGCCCATCA
TAGCAAATGCTTCAGAAACACCTCAATAAAAGAGAAAACTTGGCTTGTGTGATGGTGCAGTCACTTTACTGGACCAACCCACCCACCTTG
ACTATACCAAGGCATCATCTATCCACAGTTCTAGCCTAACTTCATGCTGATTTCTCTGCCTCTTGATTTTTCTCTGTGTGTTCCAAATAA
TCTTAAGCTGAGTTGTGGCATTTTCCATGCAACCTCCTTCTGCCAGCAGCTCACACTGCTTGAAGTCATATGAACCACTGAGGCACATCA
TGGAATTGATGTGAGCATTAAGACGTTCTCCCACACAGCCCTTCCCTGAGGCAGCAGGAGCTGGTGTGTACTGGAGACACTGTTGAACTT
GATCAAGACCCAGACCACCCCAGGTCTCCTTCGTGGGATGTCATGACGTTTGACATACCTTTGGAACGAGCCTCCTCCTTGGAAGATGGA
AGACCGTGTTCGTGGCCGACCTGGCCTCTCCTGGCCTGTTTCTTAAGATGCGGAGTCACATTTCAATGGTACGAAAAGTGGCTTCGTAAA
ATAGAAGAGCAGTCACTGTGGAACTACCAAATGGCGAGATGCTCGGTGCACATTGGGGTGCTTTGGGATAAAAGATTTATGAGCCAACTA
TTCTCTGGCACCAGATTCTAGGCCAGTTTGTTCCACTGAAGCTTTTCCCACAGCAGTCCACCTCTGCAGGCTGGCAGCCGAATGGCTTGC
CAGTGGCTCTGTGGCAAGATCACACTGAGATCGATGGGTGAGAAGGCTAGGATGCTTGTCTAGTGTTCTTAGCTGTCACGTTGGCTCCTT
CCAGGGTGGCCAGACGGTGTTGGCCACTCCCTTCTAAAACACAGGCGCCCTCCTGGTGACAGTGACCCGCCGTGGTATGCCTTGGCCCAT
TCCAGCAGTCCCAGTTATGCATTTCAAGTTTGGGGTTTGTTCTTTTCGTTAATGTTCCTCTGTGTTGTCAGCTGTCTTCATTTCCTGGGC
TAAGCAGCATTGGGAGATGTGGACCAGAGATCCACTCCTTAAGAACCAGTGGCGAAAGACACTTTCTTTCTTCACTCTGAAGTAGCTGGT
GGTACAAATGAGAACTTCAAGAGAGGATGTTATTTAGACTGAACCTCTGTTGCCAGAGATGCTGAAGATACAGACCTTGGACAGGTCAGA
GGGTTTCATTTTTGGCCTTCATCTTAGATGACTGGTTGCGTCATTTGGAGAAGTGAGTGCTCCTTGATGGTGGAATGACCGGGTGGTGGG
TACAGAACCATTGTCACAGGGATCCTGGCACAGAGAAGAGTTACGAGCAGCAGGGTGCAGGGCTTGGAAGGAATGTGGGCAAGGTTTTGA
ACTTGATTGTTCTTGAAGCTATCAGACCACATCGAGGCTCAGCAGTCATCCGTGGGCATTTGGTTTCAACAAAGAAACCTAACATCCTAC
TCTGGAAACTGATCTCGGAGTTAAGGCGAATTGTTCAAGAACACAAACTACATCGCACTCGTCAGTTGTCAGTTCTGGGGCATGACTTTA
GCGTTTTGTTTCTGCGAGAACATAACGATCACTCATTTTTATGTCCCACGTGTGTGTGTCCGCATCTTTCTGGTCAACATTGTTTTAACT
AGTCACTCATTAGCGTTTTCAATAGGGCTCTTAAGTCCAGTAGATTACGGGTAGTCAGTTGACGAAGATCTGGTTTACAAGAACTAATTA
AATGTTTCATTGCATTTTTGTAAGAACAGAATAATTTTATAAAATGTTTGTAGTTTATAATTGCCGAAAATAATTTAAAGACACTTTTTT
TTTCTCTGTGTGTGCAAATGTGTGTTTGTGATCCATTTTTTTTTTTTTTTTTTAGGACACCTGTTTACTAGCTAGCTTTACAATATGCCA
AAAAAGGATTTCTCCCTGACCCCATCCGTGGTTCACCCTCTTTTCCCCCCATGCTTTTTGCCCTAGTTTATAACAAAGGAATGATGATGA
TTTAAAAAGTAGTTCTGTATCTTCAGTATCTTGGTCTTCCAGAACCCTCTGGTTGGGAAGGGGATCATTTTTTACTGGTCATTTCCCTTT
GGAGTGTAGCTACTTTAACAGATGGAAAGAACCTCATTGGCCATGGAAACAGCCGAGGTGTTGGAGCCCAGCAGTGCATGGCACCGTTCG
GCATCTGGCTTGATTGGTCTGGCTGCCGTCATTGTCAGCACAGTGCCATGGACATGGGAAGACTTGACTGCACAGCCAATGGTTTTCATG
ATGATTACAGCATACACAGTGATCACATAAACGATGACAGCTATGGGGCACACAGGCCATTTGCTTACATGCCTCGTATCATGACTGATT
ACTGCTTTGTTAGAACACAGAAGAGACCCTATTTTATTTAAGGCAGAACCCCGAAGATACGTATTTCCAATACAGAAAAGAATTTTTAAT
AAAAACTATAACATACACAAAAATTGGTTTTAAAGTTGACTCCACTTCCTCTAACTCCAGTGGATTGTTGGCCATGTCTCCCCAACTCCA
CAATATCTCTATCATGGGAAACACCTGGGGTTTTTGCGCTACATAGGAGAAAGATCTGGAAACTATTTGGGTTTTGTTTTCAACTTTTCA
TTTGGATGTTTGGCGTTGCACACACACATCCACCGGTGGAAGAGACGCCCGGTGAAAACACCTGTCTGCTTTCTAAGCCAGTGAGGTTGA
GGTGAGAGGTTTGCCAGAGTTTGTCTACCTCTGGGTATCCCTTTGTCTGGGATAAAAAAAATCAAACCAGAAGGCGGGATGGAATGGATG
CACCGCAAATAATGCATTTTCTGAGTTTTCTTGTTAAAAAAAAATTTTTTTAAGTAAGAAAAAAAAAGGTAATAACATGGCCAATTTGTT
ACATAAAATGACTTTCTGTGTATAAATTATTCCTAAAAAATCCTGTTTATATAAAAAATCAGTAGATGAAAAAAATTTCAAAATGTTTTT
GTATATTCTGTTGTAAGAATTTATTCCTGTTATTGCGATATACTCTGGATTCTTTACATAATGGAAAAAAGAAACTGTCTATTTTGAATG
GCTGAAGCTAAGGCAACGTTAGTTTCTCTTACTCTGCTTTTTTCTAGTAAAGTACTACATGGTTTAAGTTAAATAAAATAATTCTGTATG

>53178_53178_6_MFGE8-IGF1R_MFGE8_chr15_89448988_ENST00000542878_IGF1R_chr15_99434554_ENST00000558762_length(amino acids)=1352AA_BP=199
MSSPACPFQRPRPRSMPRPRLLAALCGALLCAPSLLVALECVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTP
SSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVRLYP
TSCHTACTLRFELLGCELNVCPSTCGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCAN
ILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASEL
ENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEE
VTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDV
DLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYY
IVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPR
PERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFAR
TMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNG
SWTDPVFFYVQAKRYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSREL
GQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLR
PEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLK
DGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFR
EVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSS

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Fusion Gene PPI Analysis for MFGE8-IGF1R


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MFGE8-IGF1R


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MFGE8-IGF1R


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource