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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:APAF1-TMPO (FusionGDB2 ID:5327)

Fusion Gene Summary for APAF1-TMPO

check button Fusion gene summary
Fusion gene informationFusion gene name: APAF1-TMPO
Fusion gene ID: 5327
HgeneTgene
Gene symbol

APAF1

TMPO

Gene ID

317

7112

Gene nameapoptotic peptidase activating factor 1thymopoietin
SynonymsAPAF-1|CED4CMD1T|LAP2|LEMD4|PRO0868|TP
Cytomap

12q23.1

12q23.1

Type of geneprotein-codingprotein-coding
Descriptionapoptotic protease-activating factor 1thymopoietinLEM domain containing 4lamina-associated polypeptide 2
Modification date2020031520200313
UniProtAcc

O14727

.
Ensembl transtripts involved in fusion geneENST00000333991, ENST00000339433, 
ENST00000357310, ENST00000359972, 
ENST00000547045, ENST00000549007, 
ENST00000550527, ENST00000551964, 
ENST00000552268, ENST00000547666, 
ENST00000547743, 		ENST00000261210, 
ENST00000266732, ENST00000393053, 
ENST00000548223, ENST00000343315, 
ENST00000556029, 
Fusion gene scores* DoF score5 X 5 X 4=1007 X 7 X 3=147
# samples 57
** MAII scorelog2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/147*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: APAF1 [Title/Abstract] AND TMPO [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointAPAF1(99056584)-TMPO(98931253), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneAPAF1

GO:0006919

activation of cysteine-type endopeptidase activity involved in apoptotic process

21827945

HgeneAPAF1

GO:0008635

activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c

9267021


check buttonFusion gene breakpoints across APAF1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TMPO (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-2262-01AAPAF1chr12

99056584

+TMPOchr12

98931253

+


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Fusion Gene ORF analysis for APAF1-TMPO

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000333991ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000333991ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000333991ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000333991ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000339433ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000339433ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000339433ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000339433ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000357310ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000357310ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000357310ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000357310ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000359972ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000359972ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000359972ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000359972ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000547045ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000547045ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000547045ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000547045ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000549007ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000549007ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000549007ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000549007ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000550527ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000550527ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000550527ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000550527ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000551964ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000551964ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000551964ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000551964ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000552268ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000552268ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000552268ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
5CDS-intronENST00000552268ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000333991ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000333991ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000339433ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000339433ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000357310ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000357310ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000359972ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000359972ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000547045ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000547045ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000549007ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000549007ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000550527ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000550527ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000551964ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000551964ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000552268ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
In-frameENST00000552268ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-3CDSENST00000547666ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-3CDSENST00000547666ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-3CDSENST00000547743ENST00000343315APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-3CDSENST00000547743ENST00000556029APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547666ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547666ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547666ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547666ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547743ENST00000261210APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547743ENST00000266732APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547743ENST00000393053APAF1chr12

99056584

+TMPOchr12

98931253

+
intron-intronENST00000547743ENST00000548223APAF1chr12

99056584

+TMPOchr12

98931253

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000551964APAF1chr1299056584+ENST00000556029TMPOchr1298931253+501216917362490584
ENST00000551964APAF1chr1299056584+ENST00000343315TMPOchr1298931253+334116917362370544
ENST00000339433APAF1chr1299056584+ENST00000556029TMPOchr1298931253+485315325772331584
ENST00000339433APAF1chr1299056584+ENST00000343315TMPOchr1298931253+318215325772211544
ENST00000359972APAF1chr1299056584+ENST00000556029TMPOchr1298931253+482014995772298573
ENST00000359972APAF1chr1299056584+ENST00000343315TMPOchr1298931253+314914995772178533
ENST00000333991APAF1chr1299056584+ENST00000556029TMPOchr1298931253+485315325772331584
ENST00000333991APAF1chr1299056584+ENST00000343315TMPOchr1298931253+318215325772211544
ENST00000357310APAF1chr1299056584+ENST00000556029TMPOchr1298931253+485315325772331584
ENST00000357310APAF1chr1299056584+ENST00000343315TMPOchr1298931253+318215325772211544
ENST00000552268APAF1chr1299056584+ENST00000556029TMPOchr1298931253+4320999441798584
ENST00000552268APAF1chr1299056584+ENST00000343315TMPOchr1298931253+2649999441678544
ENST00000550527APAF1chr1299056584+ENST00000556029TMPOchr1298931253+425092971728573
ENST00000550527APAF1chr1299056584+ENST00000343315TMPOchr1298931253+257992971608533
ENST00000547045APAF1chr1299056584+ENST00000556029TMPOchr1298931253+428196051759584
ENST00000547045APAF1chr1299056584+ENST00000343315TMPOchr1298931253+261096051639544
ENST00000549007APAF1chr1299056584+ENST00000556029TMPOchr1298931253+427695501754584
ENST00000549007APAF1chr1299056584+ENST00000343315TMPOchr1298931253+260595501634544

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000551964ENST00000556029APAF1chr1299056584+TMPOchr1298931253+0.0002256830.9997743
ENST00000551964ENST00000343315APAF1chr1299056584+TMPOchr1298931253+0.0003250230.99967504
ENST00000339433ENST00000556029APAF1chr1299056584+TMPOchr1298931253+0.0002274780.9997725
ENST00000339433ENST00000343315APAF1chr1299056584+TMPOchr1298931253+0.0003388260.9996612
ENST00000359972ENST00000556029APAF1chr1299056584+TMPOchr1298931253+0.0003607080.9996393
ENST00000359972ENST00000343315APAF1chr1299056584+TMPOchr1298931253+0.0004222030.9995778
ENST00000333991ENST00000556029APAF1chr1299056584+TMPOchr1298931253+0.0002274780.9997725
ENST00000333991ENST00000343315APAF1chr1299056584+TMPOchr1298931253+0.0003388260.9996612
ENST00000357310ENST00000556029APAF1chr1299056584+TMPOchr1298931253+0.0002274780.9997725
ENST00000357310ENST00000343315APAF1chr1299056584+TMPOchr1298931253+0.0003388260.9996612
ENST00000552268ENST00000556029APAF1chr1299056584+TMPOchr1298931253+0.0002139450.9997861
ENST00000552268ENST00000343315APAF1chr1299056584+TMPOchr1298931253+0.0003143910.99968565
ENST00000550527ENST00000556029APAF1chr1299056584+TMPOchr1298931253+0.0003274140.99967265
ENST00000550527ENST00000343315APAF1chr1299056584+TMPOchr1298931253+0.0003584940.99964154
ENST00000547045ENST00000556029APAF1chr1299056584+TMPOchr1298931253+0.0002056170.9997944
ENST00000547045ENST00000343315APAF1chr1299056584+TMPOchr1298931253+0.0002968910.9997031
ENST00000549007ENST00000556029APAF1chr1299056584+TMPOchr1298931253+0.0002059460.99979407
ENST00000549007ENST00000343315APAF1chr1299056584+TMPOchr1298931253+0.0002916670.99970835

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Fusion Genomic Features for APAF1-TMPO


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
APAF1chr1299056584+TMPOchr1298931252+6.59E-050.9999341
APAF1chr1299056584+TMPOchr1298931252+6.59E-050.9999341

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for APAF1-TMPO


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:99056584/chr12:98931253)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
APAF1

O14727

.
FUNCTION: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. {ECO:0000269|PubMed:10393175, ECO:0000269|PubMed:12804598}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+7895_98318339.0Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+72695_983181206.0Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+72695_983071195.0Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+62595_983181206.0Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+62695_983071238.0Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+72795_983181249.0Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+6795_98318339.0Compositional biasNote=Poly-Ser
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781_90318339.0DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261_903181206.0DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261_903071195.0DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251_903181206.0DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261_903071238.0DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271_903181249.0DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671_90318339.0DomainCARD
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78154_161318339.0Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726154_1613181206.0Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726154_1613071195.0Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625154_1613181206.0Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626154_1613071238.0Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727154_1613181249.0Nucleotide bindingATP
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67154_161318339.0Nucleotide bindingATP
TgeneTMPOchr12:99056584chr12:98931253ENST0000026673204558_6570695.0Coiled coilOntology_term=ECO:0000250
TgeneTMPOchr12:99056584chr12:98931253ENST0000026673204109_1530695.0DomainLEM
TgeneTMPOchr12:99056584chr12:98931253ENST00000266732045_480695.0DomainLEM-like
TgeneTMPOchr12:99056584chr12:98931253ENST0000026673204190_1960695.0MotifNuclear localization signal
TgeneTMPOchr12:99056584chr12:98931253ENST000002667320449_1080695.0RegionNote=Linker
TgeneTMPOchr12:99056584chr12:98931253ENST0000039305326299_371188346.0RegionNote=Binds lamins B
TgeneTMPOchr12:99056584chr12:98931253ENST0000039305326300_374188346.0RegionNote=NAKAP95-binding C
TgeneTMPOchr12:99056584chr12:98931253ENST0000055602929299_371188455.0RegionNote=Binds lamins B
TgeneTMPOchr12:99056584chr12:98931253ENST0000055602929300_374188455.0RegionNote=NAKAP95-binding C
TgeneTMPOchr12:99056584chr12:98931253ENST0000039305326435_454188346.0Topological domainLumenal
TgeneTMPOchr12:99056584chr12:98931253ENST0000055602929435_454188455.0Topological domainLumenal
TgeneTMPOchr12:99056584chr12:98931253ENST0000039305326411_434188346.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneTMPOchr12:99056584chr12:98931253ENST0000055602929411_434188455.0TransmembraneHelical%3B Signal-anchor for type II membrane protein

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78104_415318339.0DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726104_4153181206.0DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726104_4153071195.0DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625104_4153181206.0DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626104_4153071238.0DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727104_4153181249.0DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67104_415318339.0DomainNote=NB-ARC
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78910_921318339.0RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726910_9213181206.0RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726910_9213071195.0RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625910_9213181206.0RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626910_9213071238.0RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727910_9213181249.0RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67910_921318339.0RegionInterpropeller linker
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781001_1040318339.0RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781042_1080318339.0RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781083_1122318339.0RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781125_1164318339.0RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781175_1212318339.0RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+781213_1248318339.0RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78613_652318339.0RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78655_694318339.0RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78697_738318339.0RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78741_780318339.0RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78796_836318339.0RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78838_877318339.0RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78880_910318339.0RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78922_958318339.0RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000333991+78959_998318339.0RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261001_10403181206.0RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261042_10803181206.0RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261083_11223181206.0RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261125_11643181206.0RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261175_12123181206.0RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+7261213_12483181206.0RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726613_6523181206.0RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726655_6943181206.0RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726697_7383181206.0RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726741_7803181206.0RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726796_8363181206.0RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726838_8773181206.0RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726880_9103181206.0RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726922_9583181206.0RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000357310+726959_9983181206.0RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261001_10403071195.0RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261042_10803071195.0RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261083_11223071195.0RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261125_11643071195.0RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261175_12123071195.0RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+7261213_12483071195.0RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726613_6523071195.0RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726655_6943071195.0RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726697_7383071195.0RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726741_7803071195.0RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726796_8363071195.0RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726838_8773071195.0RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726880_9103071195.0RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726922_9583071195.0RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000359972+726959_9983071195.0RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251001_10403181206.0RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251042_10803181206.0RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251083_11223181206.0RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251125_11643181206.0RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251175_12123181206.0RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+6251213_12483181206.0RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625613_6523181206.0RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625655_6943181206.0RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625697_7383181206.0RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625741_7803181206.0RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625796_8363181206.0RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625838_8773181206.0RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625880_9103181206.0RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625922_9583181206.0RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000547045+625959_9983181206.0RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261001_10403071238.0RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261042_10803071238.0RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261083_11223071238.0RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261125_11643071238.0RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261175_12123071238.0RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+6261213_12483071238.0RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626613_6523071238.0RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626655_6943071238.0RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626697_7383071238.0RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626741_7803071238.0RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626796_8363071238.0RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626838_8773071238.0RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626880_9103071238.0RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626922_9583071238.0RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000550527+626959_9983071238.0RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271001_10403181249.0RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271042_10803181249.0RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271083_11223181249.0RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271125_11643181249.0RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271175_12123181249.0RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+7271213_12483181249.0RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727613_6523181249.0RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727655_6943181249.0RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727697_7383181249.0RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727741_7803181249.0RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727796_8363181249.0RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727838_8773181249.0RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727880_9103181249.0RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727922_9583181249.0RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000551964+727959_9983181249.0RepeatNote=WD 2-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671001_1040318339.0RepeatNote=WD 2-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671042_1080318339.0RepeatNote=WD 2-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671083_1122318339.0RepeatNote=WD 2-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671125_1164318339.0RepeatNote=WD 2-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671175_1212318339.0RepeatNote=WD 2-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+671213_1248318339.0RepeatNote=WD 2-8
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67613_652318339.0RepeatNote=WD 1-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67655_694318339.0RepeatNote=WD 1-2
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67697_738318339.0RepeatNote=WD 1-3
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67741_780318339.0RepeatNote=WD 1-4
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67796_836318339.0RepeatNote=WD 1-5
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67838_877318339.0RepeatNote=WD 1-6
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67880_910318339.0RepeatNote=WD 1-7
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67922_958318339.0RepeatNote=WD 2-1
HgeneAPAF1chr12:99056584chr12:98931253ENST00000552268+67959_998318339.0RepeatNote=WD 2-2
TgeneTMPOchr12:99056584chr12:98931253ENST0000039305326109_153188346.0DomainLEM
TgeneTMPOchr12:99056584chr12:98931253ENST00000393053265_48188346.0DomainLEM-like
TgeneTMPOchr12:99056584chr12:98931253ENST0000055602929109_153188455.0DomainLEM
TgeneTMPOchr12:99056584chr12:98931253ENST00000556029295_48188455.0DomainLEM-like
TgeneTMPOchr12:99056584chr12:98931253ENST0000039305326138_243188346.0RegionNote=NAKAP95-binding N
TgeneTMPOchr12:99056584chr12:98931253ENST00000393053261_410188346.0RegionNucleoplasmic
TgeneTMPOchr12:99056584chr12:98931253ENST000003930532649_108188346.0RegionNote=Linker
TgeneTMPOchr12:99056584chr12:98931253ENST0000055602929138_243188455.0RegionNote=NAKAP95-binding N
TgeneTMPOchr12:99056584chr12:98931253ENST00000556029291_410188455.0RegionNucleoplasmic
TgeneTMPOchr12:99056584chr12:98931253ENST000005560292949_108188455.0RegionNote=Linker


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Fusion Gene Sequence for APAF1-TMPO


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>5327_5327_1_APAF1-TMPO_APAF1_chr12_99056584_ENST00000333991_TMPO_chr12_98931253_ENST00000343315_length(transcript)=3182nt_BP=1532nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTC
AAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACC
CAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAAT
GTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAG
TGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGG
ACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCA
AGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATT
TTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCA
TTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAAT
AATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTG
TGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGA
ATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACT
GCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATC
ATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGT
GTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGT
ATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGT
TAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTG

>5327_5327_1_APAF1-TMPO_APAF1_chr12_99056584_ENST00000333991_TMPO_chr12_98931253_ENST00000343315_length(amino acids)=544AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

--------------------------------------------------------------
>5327_5327_2_APAF1-TMPO_APAF1_chr12_99056584_ENST00000333991_TMPO_chr12_98931253_ENST00000556029_length(transcript)=4853nt_BP=1532nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAG
GGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAG
TACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTAT
TCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAG
AAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAA
AGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGC
AGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTT
TTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATC
TCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATG
TGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGAC
TAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATT
TCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATA
CTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGG
AAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTT
TATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACAT
ACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAG
CTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTT
AGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTA
CCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTT
ACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCC
CGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCG
TTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAA
ATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGAT
TATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAAC
CTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCA
AGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTG
AAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCA
ATAGAATCAAATGAGACAAAAATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGT
TATTTTTAAATACATCTGAAATAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAA
TTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTC
TGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGA
TGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAG
AAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATG
GTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCA
TTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAA

>5327_5327_2_APAF1-TMPO_APAF1_chr12_99056584_ENST00000333991_TMPO_chr12_98931253_ENST00000556029_length(amino acids)=584AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

--------------------------------------------------------------
>5327_5327_3_APAF1-TMPO_APAF1_chr12_99056584_ENST00000339433_TMPO_chr12_98931253_ENST00000343315_length(transcript)=3182nt_BP=1532nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTC
AAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACC
CAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAAT
GTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAG
TGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGG
ACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCA
AGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATT
TTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCA
TTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAAT
AATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTG
TGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGA
ATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACT
GCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATC
ATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGT
GTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGT
ATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGT
TAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTG

>5327_5327_3_APAF1-TMPO_APAF1_chr12_99056584_ENST00000339433_TMPO_chr12_98931253_ENST00000343315_length(amino acids)=544AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

--------------------------------------------------------------
>5327_5327_4_APAF1-TMPO_APAF1_chr12_99056584_ENST00000339433_TMPO_chr12_98931253_ENST00000556029_length(transcript)=4853nt_BP=1532nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAG
GGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAG
TACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTAT
TCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAG
AAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAA
AGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGC
AGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTT
TTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATC
TCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATG
TGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGAC
TAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATT
TCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATA
CTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGG
AAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTT
TATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACAT
ACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAG
CTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTT
AGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTA
CCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTT
ACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCC
CGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCG
TTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAA
ATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGAT
TATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAAC
CTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCA
AGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTG
AAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCA
ATAGAATCAAATGAGACAAAAATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGT
TATTTTTAAATACATCTGAAATAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAA
TTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTC
TGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGA
TGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAG
AAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATG
GTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCA
TTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAA

>5327_5327_4_APAF1-TMPO_APAF1_chr12_99056584_ENST00000339433_TMPO_chr12_98931253_ENST00000556029_length(amino acids)=584AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

--------------------------------------------------------------
>5327_5327_5_APAF1-TMPO_APAF1_chr12_99056584_ENST00000357310_TMPO_chr12_98931253_ENST00000343315_length(transcript)=3182nt_BP=1532nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTC
AAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACC
CAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAAT
GTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAG
TGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGG
ACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCA
AGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATT
TTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCA
TTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAAT
AATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTG
TGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGA
ATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACT
GCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATC
ATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGT
GTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGT
ATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGT
TAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTG

>5327_5327_5_APAF1-TMPO_APAF1_chr12_99056584_ENST00000357310_TMPO_chr12_98931253_ENST00000343315_length(amino acids)=544AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

--------------------------------------------------------------
>5327_5327_6_APAF1-TMPO_APAF1_chr12_99056584_ENST00000357310_TMPO_chr12_98931253_ENST00000556029_length(transcript)=4853nt_BP=1532nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTC
GTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCA
GAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGT
TAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAA
ACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCG
CATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTG
TCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAA
GGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAA
AGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGA
GCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAG
GGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAG
TACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTAT
TCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAG
AAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAA
AGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGC
AGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTT
TTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATC
TCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATG
TGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGAC
TAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATT
TCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATA
CTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGG
AAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTT
TATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACAT
ACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAG
CTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTT
AGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTA
CCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTT
ACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCC
CGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCG
TTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAA
ATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGAT
TATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAAC
CTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCA
AGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTG
AAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCA
ATAGAATCAAATGAGACAAAAATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGT
TATTTTTAAATACATCTGAAATAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAA
TTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTC
TGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGA
TGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAG
AAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATG
GTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCA
TTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAA

>5327_5327_6_APAF1-TMPO_APAF1_chr12_99056584_ENST00000357310_TMPO_chr12_98931253_ENST00000556029_length(amino acids)=584AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

--------------------------------------------------------------
>5327_5327_7_APAF1-TMPO_APAF1_chr12_99056584_ENST00000359972_TMPO_chr12_98931253_ENST00000343315_length(transcript)=3149nt_BP=1499nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGT
ACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATG
GGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCC
AGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGA
TGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCT
CTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGT
TACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGT
TAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAG
AGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCG
TATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGAC
TGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGC
TGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAAT
TAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAA
ATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCT
GTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGA
CCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACT
TGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACT
TCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCT
TTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAG
TATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATG
TGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAG
TACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAG
TCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAG
CTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTC
ATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATT

>5327_5327_7_APAF1-TMPO_APAF1_chr12_99056584_ENST00000359972_TMPO_chr12_98931253_ENST00000343315_length(amino acids)=533AA_BP=307
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVP
VESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRIDGPVISESTPI
AETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAA

--------------------------------------------------------------
>5327_5327_8_APAF1-TMPO_APAF1_chr12_99056584_ENST00000359972_TMPO_chr12_98931253_ENST00000556029_length(transcript)=4820nt_BP=1499nt
AAGAAGAGGTAGCGAGTGGACGTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCG
AAGACTTGAGGTGCCGCAGCGGCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGG
AAGACCTCCTCCCTTTGTGTCCAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGT
CAGGCTGCGTTGGGTGGACGCCCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAG
GCGCCTGTGAGGCCCGGACCTGCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTT
GCCGTTTCCCTCCACCGGCCTGGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCA
TGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAA
GGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCAC
TCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGA
AGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGT
ACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATG
GGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCC
AGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGA
TGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCT
CTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGT
TACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGT
TAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAG
AGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAAC
TGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAG
GAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAG
CAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAG
AAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTT
CCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGA
TTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACG
CTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGT
AAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTC
AATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTG
AAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAAT
CTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGT
ATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATT
ATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCA
ACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATA
CTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTA
ACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATT
TTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAG
AAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCC
TATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAGG
GCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGG
GCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCGTTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCA
GAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAAATAAAAAAGTACAAAAAGTACTTGCTTTTATAT
TACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGATTATTTTTTATTTTTTTATTTTTTATGAGATGGA
GTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCC
TCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCAGCCCACCTCAGCTTCCCAAAGTGCT
GGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTGAAATGGTTATCTTTGTGGATGATTTTTTTTTTT
AAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCAATAGAATCAAATGAGACAAAAATTTTAAACTGA
CTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGTTATTTTTAAATACATCTGAAATAAAAATACTTA
CTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAATTAGCCTTATTCTAATATTTAGCTTTTAGATCT
TTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTCTGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGG
GAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGATGAGCCATAGAGGGGGCACCTTTTACTCAACTT
TTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTTAGTGTTTAAAAA
TGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAACA
TGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGATGTAAATGCAAA
GCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAAAAGTAATTAACCTCTAGTTTTGTCGTTGCAATA

>5327_5327_8_APAF1-TMPO_APAF1_chr12_99056584_ENST00000359972_TMPO_chr12_98931253_ENST00000556029_length(amino acids)=573AA_BP=307
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVP
VESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITETEWTSGSSKGG
PLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEV
GEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFV

--------------------------------------------------------------
>5327_5327_9_APAF1-TMPO_APAF1_chr12_99056584_ENST00000547045_TMPO_chr12_98931253_ENST00000343315_length(transcript)=2610nt_BP=960nt
GGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACA
TGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAA
TGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATG
ATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAG
TACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGAT
GGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCC
CAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGG
ATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTC
TCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTG
TTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTG
TTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGA
GAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTC
GTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGA
CTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAG
CTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAA
TTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTA
AATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGC
TGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTG
ACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACAC
TTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGAC
TTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGC
TTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTA
GTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATAT
GTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAA
GTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAA
GTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTA
GCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGT
CATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCAT
TTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAA

>5327_5327_9_APAF1-TMPO_APAF1_chr12_99056584_ENST00000547045_TMPO_chr12_98931253_ENST00000343315_length(amino acids)=544AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

--------------------------------------------------------------
>5327_5327_10_APAF1-TMPO_APAF1_chr12_99056584_ENST00000547045_TMPO_chr12_98931253_ENST00000556029_length(transcript)=4281nt_BP=960nt
GGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACA
TGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAA
TGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATG
ATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAG
TACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGAT
GGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCC
CAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGG
ATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTC
TCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTG
TTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTG
TTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGA
GAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAA
CTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAA
GGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAA
GCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCA
GAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGT
TCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTG
ATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGAC
GCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAG
TAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTT
CAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATT
GAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAA
TCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTG
TATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAAT
TATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGC
AACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCAT
ACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGT
AACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTAT
TTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTA
GAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCC
CTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAG
GGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTG
GGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCGTTTGAACCCAGGAGGCAGAGGTTGCAGTGAGC
AGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAAATAAAAAAGTACAAAAAGTACTTGCTTTTATA
TTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGATTATTTTTTATTTTTTTATTTTTTATGAGATGG
AGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCCTGC
CTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCAGCCCACCTCAGCTTCCCAAAGTGC
TGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTGAAATGGTTATCTTTGTGGATGATTTTTTTTTT
TAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCAATAGAATCAAATGAGACAAAAATTTTAAACTG
ACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGTTATTTTTAAATACATCTGAAATAAAAATACTT
ACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAATTAGCCTTATTCTAATATTTAGCTTTTAGATC
TTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTCTGCAGAATGAGTGGGTCCTTGCAAAGTGAGTG
GGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGATGAGCCATAGAGGGGGCACCTTTTACTCAACT
TTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTTAGTGTTTAAAA
ATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAAC
ATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGATGTAAATGCAA
AGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAAAAGTAATTAACCTCTAGTTTTGTCGTTGCAAT

>5327_5327_10_APAF1-TMPO_APAF1_chr12_99056584_ENST00000547045_TMPO_chr12_98931253_ENST00000556029_length(amino acids)=584AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

--------------------------------------------------------------
>5327_5327_11_APAF1-TMPO_APAF1_chr12_99056584_ENST00000549007_TMPO_chr12_98931253_ENST00000343315_length(transcript)=2605nt_BP=955nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATA
GATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGA
AATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAA
GTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGT
GCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATAT
GTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTT
GTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCT
AGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTT
GACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCAT
TAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTAT
TTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATA
ATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAA
ACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACA
GCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCT
ATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGT
ACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCC
AGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGA

>5327_5327_11_APAF1-TMPO_APAF1_chr12_99056584_ENST00000549007_TMPO_chr12_98931253_ENST00000343315_length(amino acids)=544AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

--------------------------------------------------------------
>5327_5327_12_APAF1-TMPO_APAF1_chr12_99056584_ENST00000549007_TMPO_chr12_98931253_ENST00000556029_length(transcript)=4276nt_BP=955nt
ATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATT
AGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATA
CTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGC
ATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCA
CAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTC
ACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGG
GGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAG
AGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTG
ATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACA
GATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAAT
ATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAA
CCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAG
ACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAA
AGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAAC
GAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGA
GCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCC
TATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTC
AGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCC
ATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAAT
CCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATA
ACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAA
GCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTT
TTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTT
GGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTC
TCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAA
AGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCA
CTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACAT
ACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTT
ATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAAT
TGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATA
TTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGG
GTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGT
GATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCGTTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGA
TTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAAATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACA
TCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGATTATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCT
CACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGG
CAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGA
TTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTGAAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGC
TGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCAATAGAATCAAATGAGACAAAAATTTTAAACTGACTCA
TTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGTTATTTTTAAATACATCTGAAATAAAAATACTTACTAA
AAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAATTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCA
TACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTCTGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAA
CTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGATGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCT
TTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTG
GGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTA
GTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCAT
TTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAAAAGTAATTAACCTCTAGTTTTGTCGTTGCAATAAATG

>5327_5327_12_APAF1-TMPO_APAF1_chr12_99056584_ENST00000549007_TMPO_chr12_98931253_ENST00000556029_length(amino acids)=584AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

--------------------------------------------------------------
>5327_5327_13_APAF1-TMPO_APAF1_chr12_99056584_ENST00000550527_TMPO_chr12_98931253_ENST00000343315_length(transcript)=2579nt_BP=929nt
AGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCA
CATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAA
AATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCA
TGATGGCATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAG
GAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGG
GAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAA
ACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAA
TATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTG
GGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGT
AGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACA
AGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCC
AGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTAC
TCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCT
GCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAG
AGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGG
GGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGA
TGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTT
GGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCT
TTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGA
TTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAG
TAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCA
TTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTT
AGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAA
AGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTAT
TAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACA
GTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTA
GCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGA
TAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCA

>5327_5327_13_APAF1-TMPO_APAF1_chr12_99056584_ENST00000550527_TMPO_chr12_98931253_ENST00000343315_length(amino acids)=533AA_BP=307
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVP
VESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRIDGPVISESTPI
AETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAA

--------------------------------------------------------------
>5327_5327_14_APAF1-TMPO_APAF1_chr12_99056584_ENST00000550527_TMPO_chr12_98931253_ENST00000556029_length(transcript)=4250nt_BP=929nt
AGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACATCATGGATCA
CATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAA
AATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCA
TGATGGCATTCCTGTTGTCTCTTCTTCCAGTGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAG
GAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGG
GAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAA
ACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAA
TATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTG
GGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGT
AGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACA
AGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCC
AGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAA
AGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCG
TATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGAC
TGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGC
TGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAAT
TAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAA
ATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCT
GTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGA
CCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACT
TGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACT
TCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCT
TTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAG
TATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATG
TGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAG
TACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAG
TCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAG
CTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTC
ATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATT
TGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAG
TACAAAAAGGGCCAGGCGCGGTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAG
ACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCT
ACTAGGGAGACTGAGGCAGGAGAATCGTTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCG
ACAGAGCAAGACTCCATCTCAAAAAAAATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGT
ATACTCTTAAGAGGTGGGCATTATGATTATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGC
AGTGGCACGATCTGGGCTCGATGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGC
CAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGG
CCGGCATTATGATTTTGTGTACTCTTGAAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGA
TTAAAGTAGTAGGTGATTAAAATTTCAATAGAATCAAATGAGACAAAAATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTG
ACCATAAAGCACACTAAAAATGTAAGTTATTTTTAAATACATCTGAAATAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATT
TAGACCAGCACACAATTTTGATTTCAATTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATT
GAGACCAGAAAGACTTGTAGGTCTTTCTGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGC
CTCTCTGAGTAAAATGTTTCTTTCAGATGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATAC
TGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTA
TGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGG
TCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTA
GACTTTACAATATAATTCAATAATAAAAAGTAATTAACCTCTAGTTTTGTCGTTGCAATAAATGGTTTTCAGATAGCACAAACTGTGATT

>5327_5327_14_APAF1-TMPO_APAF1_chr12_99056584_ENST00000550527_TMPO_chr12_98931253_ENST00000556029_length(amino acids)=573AA_BP=307
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPGGVHWVSVGKQD
KSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVTDSVMGPKYVVP
VESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITETEWTSGSSKGG
PLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEV
GEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFV

--------------------------------------------------------------
>5327_5327_15_APAF1-TMPO_APAF1_chr12_99056584_ENST00000551964_TMPO_chr12_98931253_ENST00000343315_length(transcript)=3341nt_BP=1691nt
ACTTCTACGCGCGCGGGCATGAGCCGTGGCAGGAGTGCGCGGCGGCAGCGGTGGCCGCCCCTTGGGGCTTGGGGTGTGTTTATTTGCATA
AGCGGGCGCGCGCCGTCCGGGCTGGGTGGATCCGGCGGGATTTGACTGCTCCGCTGTCCAGAGGCGGAGAAGAAGAGGTAGCGAGTGGAC
GTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCGAAGACTTGAGGTGCCGCAGCG
GCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGGAAGACCTCCTCCCTTTGTGTC
CAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGTCAGGCTGCGTTGGGTGGACGC
CCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAGGCGCCTGTGAGGCCCGGACCT
GCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTTGCCGTTTCCCTCCACCGGCCT
GGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCATGGTTGACAGCTCAGAGAGAG
AAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACAT
CATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTAT
GCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGC
CCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTG
TGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGG
TGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGA
AGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACG
GTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACA
CCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAG
AGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTT
ATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAA
GCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGGTGGAAACTTC
AGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGT
CAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACC
ATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTAC
ACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTC
TTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGAT
AAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTT
TCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACA
TTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATA
TATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAAC
TTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGT
GAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAA
ACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTT
TATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACA
GTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGA
ATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAAC
ATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTC
TTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAAT

>5327_5327_15_APAF1-TMPO_APAF1_chr12_99056584_ENST00000551964_TMPO_chr12_98931253_ENST00000343315_length(amino acids)=544AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

--------------------------------------------------------------
>5327_5327_16_APAF1-TMPO_APAF1_chr12_99056584_ENST00000551964_TMPO_chr12_98931253_ENST00000556029_length(transcript)=5012nt_BP=1691nt
ACTTCTACGCGCGCGGGCATGAGCCGTGGCAGGAGTGCGCGGCGGCAGCGGTGGCCGCCCCTTGGGGCTTGGGGTGTGTTTATTTGCATA
AGCGGGCGCGCGCCGTCCGGGCTGGGTGGATCCGGCGGGATTTGACTGCTCCGCTGTCCAGAGGCGGAGAAGAAGAGGTAGCGAGTGGAC
GTGACTGCTCTATCCCGGGCAAAAGGGATAGAACCAGAGGTGGGGAGTCTGGGCAGTCGGCGACCCGCGAAGACTTGAGGTGCCGCAGCG
GCATCCGGAGTAGCGCCGGGCTCCCTCCGGGGTGCAGCCGCCGTCGGGGGAAGGGCGCCACAGGCCGGGAAGACCTCCTCCCTTTGTGTC
CAGTAGTGGGGTCCACCGGAGGGCGGCCCGTGGGCCGGGCCTCACCGCGGCGCTCCGGGACTGTGGGGTCAGGCTGCGTTGGGTGGACGC
CCACCTCGCCAACCTTCGGAGGTCCCTGGGGGTCTTCGTGCGCCCCGGGGCTGCAGAGATCCAGGGGAGGCGCCTGTGAGGCCCGGACCT
GCCCCGGGGCGAAGGGTATGTGGCGAGACAGAGCCCTGCACCCCTAATTCCCGGTGGAAAACTCCTGTTGCCGTTTCCCTCCACCGGCCT
GGAGTCTCCCAGTCTTGTCCCGGCAGTGCCGCCCTCCCCACTAAGACCTAGGCGCAAAGGCTTGGCTCATGGTTGACAGCTCAGAGAGAG
AAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTCTGGAAAAGGACATCAAGACATCCTACAT
CATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATGAGCCCACTCAACAGCAAAGAGCAGCTAT
GCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTACTACATGAAGGATATAAAGATCTTGCTGC
CCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAATAACTTCGTATGTAAGGACAGTCCTGTG
TGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAATTCAGCAGAAGCTCTCCAAATTGAAAGG
TGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAGAAGCTGTTAGAGATCATTCCCTTTTAGA
AGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTCTGATGAAACTGCAGAATCTTTGCACACG
GTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACCGTCTCCGCATTCTGATGCTTCGCAAACA
CCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACAGTCAGTGTCAGATTCTTCTTACAACCAG
AGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCTTAGGAAAGGAAAAAGGACTTGAAATTTT
ATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAGAATGTAAAGACTCTAAAATAGAGCTCAA
GCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAAGAGTTGAGCACAATCAGAGCTATTCTCA
AGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCATTAACTAGGGAATCTACAAGAGGGTCAAG
AAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTAT
AATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTC
AGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCT
TAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATT
AGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGAC
AAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGA
AACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGG
TCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGT
AGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGC
CATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATA
TGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAG
ATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTT
TTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGT
AGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGA
TCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTG
GAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTG
TTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAG
CTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCGGTGGCTTACGCCTGTAATCCCAGCACTT
TGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAA
AAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGGAGAATCGTTTGAACCCAGGAGGCAGAGG
TTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTCAAAAAAAATAAAAAAGTACAAAAAGTAC
TTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCATTATGATTATTTTTTATTTTTTTATTTT
TTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCGATGCAACCTCTGCCTCCCAGGTTCAAGC
AATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCAGCCCACCTCAGCT
TCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGTACTCTTGAAATGGTTATCTTTGTGGATG
ATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAAAATTTCAATAGAATCAAATGAGACAAAA
ATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAATGTAAGTTATTTTTAAATACATCTGAAA
TAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTGATTTCAATTAGCCTTATTCTAATATTTA
GCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAGGTCTTTCTGCAGAATGAGTGGGTCCTTG
CAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTCTTTCAGATGAGCCATAGAGGGGGCACCT
TTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTATAATTAGAAATTGTGAGAAGCTTCATTT
AGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAAAAGTATGGTCCAAATAGCAAAAATAGGA
CCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTTTATTCCATTAGAATAAATGTGTCCTTGA
TGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAATAATAAAAAGTAATTAACCTCTAGTTTT

>5327_5327_16_APAF1-TMPO_APAF1_chr12_99056584_ENST00000551964_TMPO_chr12_98931253_ENST00000556029_length(amino acids)=584AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

--------------------------------------------------------------
>5327_5327_17_APAF1-TMPO_APAF1_chr12_99056584_ENST00000552268_TMPO_chr12_98931253_ENST00000343315_length(transcript)=2649nt_BP=999nt
TAGCTCATGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTC
TGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATG
AGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTAC
TACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAA
TAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAA
TTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAG
AAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTC
TGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACC
GTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACA
GTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCT
TAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAG
AATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAA
GAGTTGAGCACAATCAGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTTCAGAGAGTACTCCCATAGCTGAAACTATAA
TGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCATCTCCTATTCTGCCAATCACTGAATTCTCAG
ACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAGAGGAAAGAAGAGTAGAAAGGGATATTCTTA
AGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGACCAATCAAAGGGGCTGCAGGCCGGCCATTAG
AACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTCCCTTGGCAGATGTCAAGTCAGAAAAGACAA
AAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTTTTTTGTTTTTGGTCTATCAAGCTATGGAAA
CCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAATGGTATCTCTTTGGCACGTTCAACTTGGTC
TCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAAAATAATGTGATTTCGCCTCAATAAATGTAG
TATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAACTTTGGACTAGTAGGAGATCACTTTGTGCCA
TATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCATCTTATTTCATTTTTGAAAAAATGTATATG
TTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACATTTAAATACTTAGAATTCTTACAGAAAAGAT
TTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAGTAAGAGGAAAAGTAACTTGGTTGTACTTTT
TGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTGTAACCTTTATTAATAGTAATGTTGTTGTAG
CCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCATTTACATACAGTAGATTTTTAGCAGAGATC
TTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGCTGTTTAGCTAGCTATAAGGCTATAATTGGA
AATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAATATGTTTTAGATAAGTGTGTGTATGTTTGTT
TAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGTCTTGTTACCAGAAACAAATTTTGCCGAGCT

>5327_5327_17_APAF1-TMPO_APAF1_chr12_99056584_ENST00000552268_TMPO_chr12_98931253_ENST00000343315_length(amino acids)=544AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQVETSEHFRI
DGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRRAPKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGIS
ASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRSIPVWIKILLFVVVAVFLFLVYQAMETNQVNPFSNFLHVDP

--------------------------------------------------------------
>5327_5327_18_APAF1-TMPO_APAF1_chr12_99056584_ENST00000552268_TMPO_chr12_98931253_ENST00000556029_length(transcript)=4320nt_BP=999nt
TAGCTCATGGTTGACAGCTCAGAGAGAGAAAGATCTGAGGGAAGATGGATGCAAAAGCTCGAAATTGTTTGCTTCAACATAGAGAAGCTC
TGGAAAAGGACATCAAGACATCCTACATCATGGATCACATGATTAGTGATGGATTTTTAACAATATCAGAAGAGGAAAAAGTAAGAAATG
AGCCCACTCAACAGCAAAGAGCAGCTATGCTGATTAAAATGATACTTAAAAAAGATAATGATTCCTACGTATCATTCTACAATGCTCTAC
TACATGAAGGATATAAAGATCTTGCTGCCCTTCTCCATGATGGCATTCCTGTTGTCTCTTCTTCCAGTGGTAAAGATTCAGTTAGTGGAA
TAACTTCGTATGTAAGGACAGTCCTGTGTGAAGGTGGAGTACCACAGAGGCCAGTTGTTTTTGTCACAAGGAAGAAGCTGGTGAATGCAA
TTCAGCAGAAGCTCTCCAAATTGAAAGGTGAACCAGGATGGGTCACCATACATGGAATGGCAGGCTGTGGGAAGTCTGTATTAGCTGCAG
AAGCTGTTAGAGATCATTCCCTTTTAGAAGGTTGTTTCCCAGGGGGAGTGCATTGGGTTTCAGTTGGGAAACAAGACAAATCTGGGCTTC
TGATGAAACTGCAGAATCTTTGCACACGGTTGGATCAGGATGAGAGTTTTTCCCAGAGGCTTCCACTTAATATTGAAGAGGCTAAAGACC
GTCTCCGCATTCTGATGCTTCGCAAACACCCAAGGTCTCTCTTGATCTTGGATGATGTTTGGGACTCTTGGGTGTTGAAAGCTTTTGACA
GTCAGTGTCAGATTCTTCTTACAACCAGAGACAAGAGTGTTACAGATTCAGTAATGGGTCCTAAATATGTAGTCCCTGTGGAGAGTTCCT
TAGGAAAGGAAAAAGGACTTGAAATTTTATCCCTTTTTGTTAATATGAAGAAGGCAGATTTGCCAGAACAAGCTCATAGTATTATAAAAG
AATGTAAAGACTCTAAAATAGAGCTCAAGCTTGAGAAGAGAGAACCACTAAAGGGCAGAGCAAAGACTCCAGTAACACTCAAGCAAAGAA
GAGTTGAGCACAATCAGAGCTATTCTCAAGCTGGAATAACTGAGACTGAATGGACAAGTGGATCTTCAAAAGGCGGACCTCTGCAGGCAT
TAACTAGGGAATCTACAAGAGGGTCAAGAAGAACTCCAAGGAAAAGGGTGGAAACTTCAGAACATTTTCGTATAGATGGTCCAGTAATTT
CAGAGAGTACTCCCATAGCTGAAACTATAATGGCTTCAAGCAACGAATCCTTAGTTGTCAATAGGGTGACTGGAAATTTCAAGCATGCAT
CTCCTATTCTGCCAATCACTGAATTCTCAGACATACCCAGAAGAGCACCAAAGAAACCATTGACAAGAGCTGAAGTGGGAGAAAAAACAG
AGGAAAGAAGAGTAGAAAGGGATATTCTTAAGGAAATGTTCCCCTATGAAGCATCTACACCAACAGGAATTAGTGCTAGTTGCCGCAGAC
CAATCAAAGGGGCTGCAGGCCGGCCATTAGAACTCAGTGATTTCAGGATGGAGGAGTCTTTTTCATCTAAATATGTTCCTAAGTATGTTC
CCTTGGCAGATGTCAAGTCAGAAAAGACAAAAAAGGGACGCTCCATTCCCGTATGGATAAAAATTTTGCTGTTTGTTGTTGTGGCAGTTT
TTTTGTTTTTGGTCTATCAAGCTATGGAAACCAACCAAGTAAATCCCTTCTCTAATTTTCTTCATGTTGACCCTAGAAAATCCAACTGAA
TGGTATCTCTTTGGCACGTTCAACTTGGTCTCCTATTTTCAATAACTGTTGAAAAACATTTGTGTACACTTGTTGACTCCAAGAACTAAA
AATAATGTGATTTCGCCTCAATAAATGTAGTATTTCATTGAAAAGCAAACAAAATATATATAAATGGACTTCATTAAAATGTTTTTGAAC
TTTGGACTAGTAGGAGATCACTTTGTGCCATATGAATAATCTTTTTTAGCTCTGGAACTTTTTGTAGGCTTTATTTTTTTAATGTGGGCA
TCTTATTTCATTTTTGAAAAAATGTATATGTTTTTTGTGTATTTGGGAAACGAAGGGTGAAACATGGTAGTATAATGTGAAGCTACACAT
TTAAATACTTAGAATTCTTACAGAAAAGATTTTAAGAATTATTCTCTGCTGAATAAAAACTGCAAATATGTGAAACATAATGAAATTCAG
TAAGAGGAAAAGTAACTTGGTTGTACTTTTTGTAACTGCAACAAAGTTTGATGGTGTTTATGAGGAAAAGTACAGCAATAATCTCTTCTG
TAACCTTTATTAATAGTAATGTTGTTGTAGCCCTATCATACTCACTTTTTAAGACACAGTATCATGAAAGTCCTATTTCAGTAAGACCCA
TTTACATACAGTAGATTTTTAGCAGAGATCTTTTAGTGTAACATACATATTTTAGAGAATTGTTGGCTAGCTGTACATGTTTTGAAAAGC
TGTTTAGCTAGCTATAAGGCTATAATTGGAAATTTGTATTTTTTATTTACAGCAAAACATTTATTCAGTCATCCAGTTTGCTACCAAAAT
ATGTTTTAGATAAGTGTGTGTATGTTTGTTTAGAAGTTAGAAATTGTAAACACTGGTCTTATGTTTCATTTGGATTCATTATTGCATTGT
CTTGTTACCAGAAACAAATTTTGCCGAGCTTTTTTTGCCCTATATTTCCCAGCATAATTTGATTAGAAAGTACAAAAAGGGCCAGGCGCG
GTGGCTTACGCCTGTAATCCCAGCACTTTGGGAGGCCAGGGCGGGTGGATCACGAGGTCAAGAGATCAAGACCATCCTGGCCAACATGGT
GAAACCCCGTCTCTACTAAAAATACAAAAAAATTAGCTGGGCGTGATGATGTGCGCCTGTAGTCCTGTCTACTAGGGAGACTGAGGCAGG
AGAATCGTTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCAGAGATTACGTCACTGCACTGTAGCCTGGCGACAGAGCAAGACTCCATCTC
AAAAAAAATAAAAAAGTACAAAAAGTACTTGCTTTTATATTACATCATAAGCAGTAGTTAATAAAGTTGTATACTCTTAAGAGGTGGGCA
TTATGATTATTTTTTATTTTTTTATTTTTTATGAGATGGAGTCTCACTCTTGTCACCCAGACTGTAGTGCAGTGGCACGATCTGGGCTCG
ATGCAACCTCTGCCTCCCAGGTTCAAGCAATTTTCCTGCCTCGGCAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCT
GACCTCAAGTGATCAGCCCACCTCAGCTTCCCAAAGTGCTGGGATTACAGGTGTGATCCACTGCACCCGGCCGGCATTATGATTTTGTGT
ACTCTTGAAATGGTTATCTTTGTGGATGATTTTTTTTTTTAAGCTGAAACTTACCTCATGAATAACTTGATTAAAGTAGTAGGTGATTAA
AATTTCAATAGAATCAAATGAGACAAAAATTTTAAACTGACTCATTTGAGTTTCAACTTTACAGTCATTGACCATAAAGCACACTAAAAA
TGTAAGTTATTTTTAAATACATCTGAAATAAAAATACTTACTAAAAAGGAAGAAGCCGAAGATGTATATTTAGACCAGCACACAATTTTG
ATTTCAATTAGCCTTATTCTAATATTTAGCTTTTAGATCTTTCATACACATTTTCACGTACTTTGCAATTGAGACCAGAAAGACTTGTAG
GTCTTTCTGCAGAATGAGTGGGTCCTTGCAAAGTGAGTGGGAAACTTACTCCTAGATCAGAAATGTTTGCCTCTCTGAGTAAAATGTTTC
TTTCAGATGAGCCATAGAGGGGGCACCTTTTACTCAACTTTTCTTTGTTTTGAAACTTTGTTTCCCATACTGTTTTCAGCCTTTTGTTTA
TAATTAGAAATTGTGAGAAGCTTCATTTAGTGTTTAAAAATGTGGGGAGATAAATCAGACTTAACATGTATGTAAGATCAATTCACTTAA
AAGTATGGTCCAAATAGCAAAAATAGGACCAGGTGAAACATGTAGTCATTTTTTAAAAACATGTACTTGGTCTTTTGTGTGTGTCTGTTT
TATTCCATTAGAATAAATGTGTCCTTGATGTAAATGCAAAGCATTTCTTCCTGATTAAATTGTAGATGTAGACTTTACAATATAATTCAA
TAATAAAAAGTAATTAACCTCTAGTTTTGTCGTTGCAATAAATGGTTTTCAGATAGCACAAACTGTGATTTCTGGATAACATTTCTTATG

>5327_5327_18_APAF1-TMPO_APAF1_chr12_99056584_ENST00000552268_TMPO_chr12_98931253_ENST00000556029_length(amino acids)=584AA_BP=318
MDAKARNCLLQHREALEKDIKTSYIMDHMISDGFLTISEEEKVRNEPTQQQRAAMLIKMILKKDNDSYVSFYNALLHEGYKDLAALLHDG
IPVVSSSSGKDSVSGITSYVRTVLCEGGVPQRPVVFVTRKKLVNAIQQKLSKLKGEPGWVTIHGMAGCGKSVLAAEAVRDHSLLEGCFPG
GVHWVSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLLILDDVWDSWVLKAFDSQCQILLTTRDKSVT
DSVMGPKYVVPVESSLGKEKGLEILSLFVNMKKADLPEQAHSIIKECKDSKIELKLEKREPLKGRAKTPVTLKQRRVEHNQSYSQAGITE
TEWTSGSSKGGPLQALTRESTRGSRRTPRKRVETSEHFRIDGPVISESTPIAETIMASSNESLVVNRVTGNFKHASPILPITEFSDIPRR
APKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVKSEKTKKGRS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for APAF1-TMPO


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for APAF1-TMPO


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for APAF1-TMPO


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource