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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:MGST3-UCK2 (FusionGDB2 ID:53457)

Fusion Gene Summary for MGST3-UCK2

Fusion gene summary

Fusion gene information	Fusion gene name: MGST3-UCK2
	Fusion gene ID: 53457
		Hgene	Tgene
	Gene symbol	MGST3	UCK2
	Gene ID	4259	7371
	Gene name	microsomal glutathione S-transferase 3	uridine-cytidine kinase 2
	Synonyms	GST-III	TSA903\|UK\|UMPK
	Cytomap	1q24.1	1q24.1
	Type of gene	protein-coding	protein-coding
	Description	microsomal glutathione S-transferase 3LTC4 synthase MGST3glutathione peroxidase MGST3microsomal GST-3microsomal GST-IIImicrosomal glutathione S-transferase III	uridine-cytidine kinase 2cytidine monophosphokinase 2testis-specific protein TSA903uridine kinaseuridine monophosphate kinaseuridine monophosphokinase 2
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000367883, ENST00000367884, ENST00000367885, ENST00000367886, ENST00000367888, ENST00000367889, ENST00000461759,	ENST00000462329, ENST00000469256, ENST00000470820, ENST00000367879, ENST00000372212,
Fusion gene scores	* DoF score	6 X 5 X 4=120	7 X 5 X 5=175
	# samples	6	7
	** MAII score	log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(7/175*10)=-1.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: MGST3 [Title/Abstract] AND UCK2 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	MGST3(165600530)-UCK2(165859441), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	MGST3	GO:0006629	lipid metabolic process	9278457
Hgene	MGST3	GO:0019370	leukotriene biosynthetic process	9278457

Fusion gene breakpoints across MGST3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across UCK2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-BL-A13J-01A	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
ChimerDB4	BLCA	TCGA-BL-A13J-01A	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+

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Fusion Gene ORF analysis for MGST3-UCK2

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000367883	ENST00000462329	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367883	ENST00000469256	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367883	ENST00000470820	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367884	ENST00000462329	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367884	ENST00000469256	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367884	ENST00000470820	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367885	ENST00000462329	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367885	ENST00000469256	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367885	ENST00000470820	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367886	ENST00000462329	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367886	ENST00000469256	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367886	ENST00000470820	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367888	ENST00000462329	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367888	ENST00000469256	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367888	ENST00000470820	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367889	ENST00000462329	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367889	ENST00000469256	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5CDS-intron	ENST00000367889	ENST00000470820	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
5UTR-3CDS	ENST00000367884	ENST00000367879	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-3CDS	ENST00000367884	ENST00000372212	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-3CDS	ENST00000367885	ENST00000367879	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-3CDS	ENST00000367885	ENST00000372212	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-3CDS	ENST00000367888	ENST00000367879	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-3CDS	ENST00000367888	ENST00000372212	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-3CDS	ENST00000367889	ENST00000367879	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-3CDS	ENST00000367889	ENST00000372212	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367884	ENST00000462329	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367884	ENST00000469256	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367884	ENST00000470820	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367885	ENST00000462329	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367885	ENST00000469256	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367885	ENST00000470820	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367888	ENST00000462329	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367888	ENST00000469256	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367888	ENST00000470820	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367889	ENST00000462329	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367889	ENST00000469256	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
5UTR-intron	ENST00000367889	ENST00000470820	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
In-frame	ENST00000367883	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
In-frame	ENST00000367883	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
In-frame	ENST00000367884	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
In-frame	ENST00000367884	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
In-frame	ENST00000367885	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
In-frame	ENST00000367885	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
In-frame	ENST00000367886	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
In-frame	ENST00000367886	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
In-frame	ENST00000367888	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
In-frame	ENST00000367888	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
In-frame	ENST00000367889	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
In-frame	ENST00000367889	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
intron-3CDS	ENST00000367883	ENST00000367879	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-3CDS	ENST00000367883	ENST00000372212	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-3CDS	ENST00000367886	ENST00000367879	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-3CDS	ENST00000367886	ENST00000372212	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-3CDS	ENST00000461759	ENST00000367879	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-3CDS	ENST00000461759	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
intron-3CDS	ENST00000461759	ENST00000372212	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-3CDS	ENST00000461759	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
intron-intron	ENST00000367883	ENST00000462329	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-intron	ENST00000367883	ENST00000469256	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-intron	ENST00000367883	ENST00000470820	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-intron	ENST00000367886	ENST00000462329	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-intron	ENST00000367886	ENST00000469256	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-intron	ENST00000367886	ENST00000470820	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-intron	ENST00000461759	ENST00000462329	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-intron	ENST00000461759	ENST00000462329	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
intron-intron	ENST00000461759	ENST00000469256	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-intron	ENST00000461759	ENST00000469256	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+
intron-intron	ENST00000461759	ENST00000470820	MGST3	chr1	165600530	+	UCK2	chr1	165859441	+
intron-intron	ENST00000461759	ENST00000470820	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000367889	MGST3	chr1	165619201	+	ENST00000367879	UCK2	chr1	165859441	+	1530	557	440	1243	267
ENST00000367889	MGST3	chr1	165619201	+	ENST00000372212	UCK2	chr1	165859441	+	1648	557	440	850	136
ENST00000367888	MGST3	chr1	165619201	+	ENST00000367879	UCK2	chr1	165859441	+	1178	205	88	891	267
ENST00000367888	MGST3	chr1	165619201	+	ENST00000372212	UCK2	chr1	165859441	+	1296	205	88	498	136
ENST00000367885	MGST3	chr1	165619201	+	ENST00000367879	UCK2	chr1	165859441	+	1195	222	21	908	295
ENST00000367885	MGST3	chr1	165619201	+	ENST00000372212	UCK2	chr1	165859441	+	1313	222	21	515	164
ENST00000367884	MGST3	chr1	165619201	+	ENST00000367879	UCK2	chr1	165859441	+	1231	258	141	944	267
ENST00000367884	MGST3	chr1	165619201	+	ENST00000372212	UCK2	chr1	165859441	+	1349	258	141	551	136
ENST00000367883	MGST3	chr1	165619201	+	ENST00000367879	UCK2	chr1	165859441	+	1221	248	89	934	281
ENST00000367883	MGST3	chr1	165619201	+	ENST00000372212	UCK2	chr1	165859441	+	1339	248	89	541	150
ENST00000367886	MGST3	chr1	165619201	+	ENST00000367879	UCK2	chr1	165859441	+	1132	159	0	845	281
ENST00000367886	MGST3	chr1	165619201	+	ENST00000372212	UCK2	chr1	165859441	+	1250	159	0	452	150

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000367889	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.001820944	0.9981791
ENST00000367889	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.006870097	0.9931299
ENST00000367888	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.001354895	0.9986451
ENST00000367888	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.00775397	0.9922461
ENST00000367885	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.001644214	0.9983558
ENST00000367885	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.006470322	0.99352974
ENST00000367884	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.000705203	0.99929476
ENST00000367884	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.003001071	0.9969989
ENST00000367883	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.001358168	0.9986418
ENST00000367883	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.00515645	0.9948435
ENST00000367886	ENST00000367879	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.001381806	0.99861825
ENST00000367886	ENST00000372212	MGST3	chr1	165619201	+	UCK2	chr1	165859441	+	0.005769337	0.9942306

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Fusion Genomic Features for MGST3-UCK2

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MGST3-UCK2

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:165600530/chr1:165859441)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

MGST3

chr1:165619201

chr1:165859441

ENST00000367884

9_29

153.0

Transmembrane

Helical

Hgene

MGST3

chr1:165619201

chr1:165859441

ENST00000367889

9_29

153.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

MGST3

chr1:165619201

chr1:165859441

ENST00000367884

120_140

153.0

Transmembrane

Helical

Hgene

MGST3

chr1:165619201

chr1:165859441

ENST00000367884

71_91

153.0

Transmembrane

Helical

Hgene

MGST3

chr1:165619201

chr1:165859441

ENST00000367889

120_140

153.0

Transmembrane

Helical

Hgene

MGST3

chr1:165619201

chr1:165859441

ENST00000367889

71_91

153.0

Transmembrane

Helical

Tgene

UCK2

chr1:165619201

chr1:165859441

ENST00000367879

27_35

262.0

Nucleotide binding

Note=ATP

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Fusion Gene Sequence for MGST3-UCK2

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>53457_53457_1_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367883_UCK2_chr1_165859441_ENST00000367879_length(transcript)=1221nt_BP=248nt
ATTCCCCGAAGTTGTGGCTTCTGCTGATACTTTCCTTGAGAGTCACGAGTTTACAAGCTACATAATAGCGTCGGGGGCAAGGACAGGAGA
TGCCCTGGAGGGGAAGGCGCTTCCGGCTCTGCAGACGCAAGATGGCTGTCCTCTCTAAGGAATATGGTTTTGTGCTTCTAACTGGTGCTG
CCAGCTTTATAATGGTGGCCCACCTAGCCATCAATGTTTCCAAGGCCCGCAAGAAGTACAAAGTGGAGTCTTCCGTGTGTGCTAAGATCG
TGCAGCTCCTGGGGCAGAATGAGGTGGACTATCGCCAGAAGCAGGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCGG
AGCAGAAGGCCAAAGCCCTGAAGGGCCAGTTCAACTTTGACCACCCGGATGCCTTTGACAATGAACTCATTCTCAAAACACTCAAAGAAA
TCACTGAAGGGAAAACAGTCCAGATCCCCGTGTATGACTTTGTCTCCCATTCCCGGAAGGAGGAGACAGTTACTGTCTATCCCGCAGACG
TGGTGCTCTTTGAAGGGATCCTGGCCTTCTACTCCCAGGAGGTACGAGACCTGTTCCAGATGAAGCTTTTTGTGGATACAGATGCGGACA
CCCGGCTCTCACGCAGAGTATTAAGGGACATCAGCGAGAGAGGCAGGGATCTTGAGCAGATTTTATCTCAGTACATTACGTTCGTCAAGC
CTGCCTTTGAGGAATTCTGCTTGCCAACAAAGAAGTATGCTGATGTGATCATCCCTAGAGGTGCAGATAATCTGGTGGCCATCAACCTCA
TCGTGCAGCACATCCAGGACATCCTGAATGGAGGGCCCTCCAAACGGCAGACCAATGGCTGTCTCAACGGCTACACCCCTTCACGCAAGA
GGCAGGCATCGGAGTCCAGCAGCAGGCCGCATTGACCCGTCTCCATCGGACCCCAGCCCCTATCTCCAAGAGACAGAGGAGGGGTCAGGA
GGCACTGCTCATCTGTACATACTGTTTCCTATGACATTACTGTATTTAAGAAAACACCATGGAGATGAAATGCCTTTGATTTTTTTTTTC
TTTTTGTACTTTGGAACGACAAAATGAAACAGAACTTGACCCTGAGCTTAAATAACAAAACTGTGCCAACTACTACTGGTGATGCCTAAT

>53457_53457_1_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367883_UCK2_chr1_165859441_ENST00000367879_length(amino acids)=281AA_BP=0
MPWRGRRFRLCRRKMAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTS
EQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDAD
TRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNGGPSKRQTNGCLNGYTPSRK

--------------------------------------------------------------
>53457_53457_2_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367883_UCK2_chr1_165859441_ENST00000372212_length(transcript)=1339nt_BP=248nt
ATTCCCCGAAGTTGTGGCTTCTGCTGATACTTTCCTTGAGAGTCACGAGTTTACAAGCTACATAATAGCGTCGGGGGCAAGGACAGGAGA
TGCCCTGGAGGGGAAGGCGCTTCCGGCTCTGCAGACGCAAGATGGCTGTCCTCTCTAAGGAATATGGTTTTGTGCTTCTAACTGGTGCTG
CCAGCTTTATAATGGTGGCCCACCTAGCCATCAATGTTTCCAAGGCCCGCAAGAAGTACAAAGTGGAGTCTTCCGTGTGTGCTAAGATCG
TGCAGCTCCTGGGGCAGAATGAGGTGGACTATCGCCAGAAGCAGGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCGG
AGCAGAAGGCCAAAGCCCTGAAGGGCCAGTTCAACTTTGACCACCCGGATGCCTTTGACAATGAACTCATTCTCAAAACACTCAAAGAAA
TCACTGAAGGGAAAACAGTCCAGATCCCCGTGTATGACTTTGTCTCCCATTCCCGTATTAAGGGACATCAGCGAGAGAGGCAGGGATCTT
GAGCAGATTTTATCTCAGTACATTACGTTCGTCAAGCCTGCCTTTGAGGAATTCTGCTTGCCAACAAAGAAGTATGCTGATGTGATCATC
CCTAGAGGTGCAGATAATCTGGTGGCCATCAACCTCATCGTGCAGCACATCCAGGACATCCTGAATGGAGGGCCCTCCAAACGGCAGACC
AATGGCTGTCTCAACGGCTACACCCCTTCACGCAAGAGGCAGGCATCGGAGTCCAGCAGCAGGCCGCATTGACCCGTCTCCATCGGACCC
CAGCCCCTATCTCCAAGAGACAGAGGAGGGGTCAGGAGGCACTGCTCATCTGTACATACTGTTTCCTATGACATTACTGTATTTAAGAAA
ACACCATGGAGATGAAATGCCTTTGATTTTTTTTTTCTTTTTGTACTTTGGAACGACAAAATGAAACAGAACTTGACCCTGAGCTTAAAT
AACAAAACTGTGCCAACTACTACTGGTGATGCCTAATTATGAATCCAACGTGTAACCAGTTATAAATACATATATATATAAAAAAGGATC
TATTTTTGTGTAAATGTACAAATACTGTAAAGCTGTTTGCCATAAGTATTTTGCAGGAGGGTCTGTACTTGAGTGTTTTAGGACTGGAGC
TGGAATTTCACCAAGGGGAAATTGCCTGTTGTGTCCCAGGGTGGGGAGGCTCGGGCATCTGTGAGAGACAGGGAGGGTGGCTAAGGTCCA

>53457_53457_2_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367883_UCK2_chr1_165859441_ENST00000372212_length(amino acids)=150AA_BP=0
MPWRGRRFRLCRRKMAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTS

--------------------------------------------------------------
>53457_53457_3_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367884_UCK2_chr1_165859441_ENST00000367879_length(transcript)=1231nt_BP=258nt
GCAGTTTTGTTCTGCTCCAGCTGTTCGAAGGTGATCCAGGACAGATCTTCCATCCTCCTAACATATAGTTAGCTTCCACTCTCCAAATAT
TCCACCAGCAACATTGATGAATATTGAAGACTATGGACTGTGAGACGCAAGATGGCTGTCCTCTCTAAGGAATATGGTTTTGTGCTTCTA
ACTGGTGCTGCCAGCTTTATAATGGTGGCCCACCTAGCCATCAATGTTTCCAAGGCCCGCAAGAAGTACAAAGTGGAGTCTTCCGTGTGT
GCTAAGATCGTGCAGCTCCTGGGGCAGAATGAGGTGGACTATCGCCAGAAGCAGGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTC
CTTACCTCGGAGCAGAAGGCCAAAGCCCTGAAGGGCCAGTTCAACTTTGACCACCCGGATGCCTTTGACAATGAACTCATTCTCAAAACA
CTCAAAGAAATCACTGAAGGGAAAACAGTCCAGATCCCCGTGTATGACTTTGTCTCCCATTCCCGGAAGGAGGAGACAGTTACTGTCTAT
CCCGCAGACGTGGTGCTCTTTGAAGGGATCCTGGCCTTCTACTCCCAGGAGGTACGAGACCTGTTCCAGATGAAGCTTTTTGTGGATACA
GATGCGGACACCCGGCTCTCACGCAGAGTATTAAGGGACATCAGCGAGAGAGGCAGGGATCTTGAGCAGATTTTATCTCAGTACATTACG
TTCGTCAAGCCTGCCTTTGAGGAATTCTGCTTGCCAACAAAGAAGTATGCTGATGTGATCATCCCTAGAGGTGCAGATAATCTGGTGGCC
ATCAACCTCATCGTGCAGCACATCCAGGACATCCTGAATGGAGGGCCCTCCAAACGGCAGACCAATGGCTGTCTCAACGGCTACACCCCT
TCACGCAAGAGGCAGGCATCGGAGTCCAGCAGCAGGCCGCATTGACCCGTCTCCATCGGACCCCAGCCCCTATCTCCAAGAGACAGAGGA
GGGGTCAGGAGGCACTGCTCATCTGTACATACTGTTTCCTATGACATTACTGTATTTAAGAAAACACCATGGAGATGAAATGCCTTTGAT
TTTTTTTTTCTTTTTGTACTTTGGAACGACAAAATGAAACAGAACTTGACCCTGAGCTTAAATAACAAAACTGTGCCAACTACTACTGGT

>53457_53457_3_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367884_UCK2_chr1_165859441_ENST00000367879_length(amino acids)=267AA_BP=0
MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFD
HPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISER

--------------------------------------------------------------
>53457_53457_4_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367884_UCK2_chr1_165859441_ENST00000372212_length(transcript)=1349nt_BP=258nt
GCAGTTTTGTTCTGCTCCAGCTGTTCGAAGGTGATCCAGGACAGATCTTCCATCCTCCTAACATATAGTTAGCTTCCACTCTCCAAATAT
TCCACCAGCAACATTGATGAATATTGAAGACTATGGACTGTGAGACGCAAGATGGCTGTCCTCTCTAAGGAATATGGTTTTGTGCTTCTA
ACTGGTGCTGCCAGCTTTATAATGGTGGCCCACCTAGCCATCAATGTTTCCAAGGCCCGCAAGAAGTACAAAGTGGAGTCTTCCGTGTGT
GCTAAGATCGTGCAGCTCCTGGGGCAGAATGAGGTGGACTATCGCCAGAAGCAGGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTC
CTTACCTCGGAGCAGAAGGCCAAAGCCCTGAAGGGCCAGTTCAACTTTGACCACCCGGATGCCTTTGACAATGAACTCATTCTCAAAACA
CTCAAAGAAATCACTGAAGGGAAAACAGTCCAGATCCCCGTGTATGACTTTGTCTCCCATTCCCGTATTAAGGGACATCAGCGAGAGAGG
CAGGGATCTTGAGCAGATTTTATCTCAGTACATTACGTTCGTCAAGCCTGCCTTTGAGGAATTCTGCTTGCCAACAAAGAAGTATGCTGA
TGTGATCATCCCTAGAGGTGCAGATAATCTGGTGGCCATCAACCTCATCGTGCAGCACATCCAGGACATCCTGAATGGAGGGCCCTCCAA
ACGGCAGACCAATGGCTGTCTCAACGGCTACACCCCTTCACGCAAGAGGCAGGCATCGGAGTCCAGCAGCAGGCCGCATTGACCCGTCTC
CATCGGACCCCAGCCCCTATCTCCAAGAGACAGAGGAGGGGTCAGGAGGCACTGCTCATCTGTACATACTGTTTCCTATGACATTACTGT
ATTTAAGAAAACACCATGGAGATGAAATGCCTTTGATTTTTTTTTTCTTTTTGTACTTTGGAACGACAAAATGAAACAGAACTTGACCCT
GAGCTTAAATAACAAAACTGTGCCAACTACTACTGGTGATGCCTAATTATGAATCCAACGTGTAACCAGTTATAAATACATATATATATA
AAAAAGGATCTATTTTTGTGTAAATGTACAAATACTGTAAAGCTGTTTGCCATAAGTATTTTGCAGGAGGGTCTGTACTTGAGTGTTTTA
GGACTGGAGCTGGAATTTCACCAAGGGGAAATTGCCTGTTGTGTCCCAGGGTGGGGAGGCTCGGGCATCTGTGAGAGACAGGGAGGGTGG

>53457_53457_4_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367884_UCK2_chr1_165859441_ENST00000372212_length(amino acids)=136AA_BP=0
MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFD

--------------------------------------------------------------
>53457_53457_5_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367885_UCK2_chr1_165859441_ENST00000367879_length(transcript)=1195nt_BP=222nt
CCCACACCGCGCTGCGCAGTTTTGTTCTGCTCCAGCTGTTCGAAGGTGATCCAGGGACAGGAGATGCCCTGGAGGGGAAGGCGCTTCCGG
CTCTGCAGACGCAAGATGGCTGTCCTCTCTAAGGAATATGGTTTTGTGCTTCTAACTGGTGCTGCCAGCTTTATAATGGTGGCCCACCTA
GCCATCAATGTTTCCAAGGCCCGCAAGAAGTACAAAGTGGAGTCTTCCGTGTGTGCTAAGATCGTGCAGCTCCTGGGGCAGAATGAGGTG
GACTATCGCCAGAAGCAGGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCGGAGCAGAAGGCCAAAGCCCTGAAGGGC
CAGTTCAACTTTGACCACCCGGATGCCTTTGACAATGAACTCATTCTCAAAACACTCAAAGAAATCACTGAAGGGAAAACAGTCCAGATC
CCCGTGTATGACTTTGTCTCCCATTCCCGGAAGGAGGAGACAGTTACTGTCTATCCCGCAGACGTGGTGCTCTTTGAAGGGATCCTGGCC
TTCTACTCCCAGGAGGTACGAGACCTGTTCCAGATGAAGCTTTTTGTGGATACAGATGCGGACACCCGGCTCTCACGCAGAGTATTAAGG
GACATCAGCGAGAGAGGCAGGGATCTTGAGCAGATTTTATCTCAGTACATTACGTTCGTCAAGCCTGCCTTTGAGGAATTCTGCTTGCCA
ACAAAGAAGTATGCTGATGTGATCATCCCTAGAGGTGCAGATAATCTGGTGGCCATCAACCTCATCGTGCAGCACATCCAGGACATCCTG
AATGGAGGGCCCTCCAAACGGCAGACCAATGGCTGTCTCAACGGCTACACCCCTTCACGCAAGAGGCAGGCATCGGAGTCCAGCAGCAGG
CCGCATTGACCCGTCTCCATCGGACCCCAGCCCCTATCTCCAAGAGACAGAGGAGGGGTCAGGAGGCACTGCTCATCTGTACATACTGTT
TCCTATGACATTACTGTATTTAAGAAAACACCATGGAGATGAAATGCCTTTGATTTTTTTTTTCTTTTTGTACTTTGGAACGACAAAATG
AAACAGAACTTGACCCTGAGCTTAAATAACAAAACTGTGCCAACTACTACTGGTGATGCCTAATTATGAATCCAACGTGTAACCAGTTAT

>53457_53457_5_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367885_UCK2_chr1_165859441_ENST00000367879_length(amino acids)=295AA_BP=1
MFCSSCSKVIQGQEMPWRGRRFRLCRRKMAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQV
VILSQDSFYRVLTSEQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVR
DLFQMKLFVDTDADTRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNGGPSKR

--------------------------------------------------------------
>53457_53457_6_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367885_UCK2_chr1_165859441_ENST00000372212_length(transcript)=1313nt_BP=222nt
CCCACACCGCGCTGCGCAGTTTTGTTCTGCTCCAGCTGTTCGAAGGTGATCCAGGGACAGGAGATGCCCTGGAGGGGAAGGCGCTTCCGG
CTCTGCAGACGCAAGATGGCTGTCCTCTCTAAGGAATATGGTTTTGTGCTTCTAACTGGTGCTGCCAGCTTTATAATGGTGGCCCACCTA
GCCATCAATGTTTCCAAGGCCCGCAAGAAGTACAAAGTGGAGTCTTCCGTGTGTGCTAAGATCGTGCAGCTCCTGGGGCAGAATGAGGTG
GACTATCGCCAGAAGCAGGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCGGAGCAGAAGGCCAAAGCCCTGAAGGGC
CAGTTCAACTTTGACCACCCGGATGCCTTTGACAATGAACTCATTCTCAAAACACTCAAAGAAATCACTGAAGGGAAAACAGTCCAGATC
CCCGTGTATGACTTTGTCTCCCATTCCCGTATTAAGGGACATCAGCGAGAGAGGCAGGGATCTTGAGCAGATTTTATCTCAGTACATTAC
GTTCGTCAAGCCTGCCTTTGAGGAATTCTGCTTGCCAACAAAGAAGTATGCTGATGTGATCATCCCTAGAGGTGCAGATAATCTGGTGGC
CATCAACCTCATCGTGCAGCACATCCAGGACATCCTGAATGGAGGGCCCTCCAAACGGCAGACCAATGGCTGTCTCAACGGCTACACCCC
TTCACGCAAGAGGCAGGCATCGGAGTCCAGCAGCAGGCCGCATTGACCCGTCTCCATCGGACCCCAGCCCCTATCTCCAAGAGACAGAGG
AGGGGTCAGGAGGCACTGCTCATCTGTACATACTGTTTCCTATGACATTACTGTATTTAAGAAAACACCATGGAGATGAAATGCCTTTGA
TTTTTTTTTTCTTTTTGTACTTTGGAACGACAAAATGAAACAGAACTTGACCCTGAGCTTAAATAACAAAACTGTGCCAACTACTACTGG
TGATGCCTAATTATGAATCCAACGTGTAACCAGTTATAAATACATATATATATAAAAAAGGATCTATTTTTGTGTAAATGTACAAATACT
GTAAAGCTGTTTGCCATAAGTATTTTGCAGGAGGGTCTGTACTTGAGTGTTTTAGGACTGGAGCTGGAATTTCACCAAGGGGAAATTGCC
TGTTGTGTCCCAGGGTGGGGAGGCTCGGGCATCTGTGAGAGACAGGGAGGGTGGCTAAGGTCCAGTTGCTTTTGAGTGCCCCGTGGAACT

>53457_53457_6_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367885_UCK2_chr1_165859441_ENST00000372212_length(amino acids)=164AA_BP=1
MFCSSCSKVIQGQEMPWRGRRFRLCRRKMAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQV

--------------------------------------------------------------
>53457_53457_7_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367886_UCK2_chr1_165859441_ENST00000367879_length(transcript)=1132nt_BP=159nt
ATGCCCTGGAGGGGAAGGCGCTTCCGGCTCTGCAGACGCAAGATGGCTGTCCTCTCTAAGGAATATGGTTTTGTGCTTCTAACTGGTGCT
GCCAGCTTTATAATGGTGGCCCACCTAGCCATCAATGTTTCCAAGGCCCGCAAGAAGTACAAAGTGGAGTCTTCCGTGTGTGCTAAGATC
GTGCAGCTCCTGGGGCAGAATGAGGTGGACTATCGCCAGAAGCAGGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCG
GAGCAGAAGGCCAAAGCCCTGAAGGGCCAGTTCAACTTTGACCACCCGGATGCCTTTGACAATGAACTCATTCTCAAAACACTCAAAGAA
ATCACTGAAGGGAAAACAGTCCAGATCCCCGTGTATGACTTTGTCTCCCATTCCCGGAAGGAGGAGACAGTTACTGTCTATCCCGCAGAC
GTGGTGCTCTTTGAAGGGATCCTGGCCTTCTACTCCCAGGAGGTACGAGACCTGTTCCAGATGAAGCTTTTTGTGGATACAGATGCGGAC
ACCCGGCTCTCACGCAGAGTATTAAGGGACATCAGCGAGAGAGGCAGGGATCTTGAGCAGATTTTATCTCAGTACATTACGTTCGTCAAG
CCTGCCTTTGAGGAATTCTGCTTGCCAACAAAGAAGTATGCTGATGTGATCATCCCTAGAGGTGCAGATAATCTGGTGGCCATCAACCTC
ATCGTGCAGCACATCCAGGACATCCTGAATGGAGGGCCCTCCAAACGGCAGACCAATGGCTGTCTCAACGGCTACACCCCTTCACGCAAG
AGGCAGGCATCGGAGTCCAGCAGCAGGCCGCATTGACCCGTCTCCATCGGACCCCAGCCCCTATCTCCAAGAGACAGAGGAGGGGTCAGG
AGGCACTGCTCATCTGTACATACTGTTTCCTATGACATTACTGTATTTAAGAAAACACCATGGAGATGAAATGCCTTTGATTTTTTTTTT
CTTTTTGTACTTTGGAACGACAAAATGAAACAGAACTTGACCCTGAGCTTAAATAACAAAACTGTGCCAACTACTACTGGTGATGCCTAA

>53457_53457_7_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367886_UCK2_chr1_165859441_ENST00000367879_length(amino acids)=281AA_BP=0
MPWRGRRFRLCRRKMAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTS
EQKAKALKGQFNFDHPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDAD
TRLSRRVLRDISERGRDLEQILSQYITFVKPAFEEFCLPTKKYADVIIPRGADNLVAINLIVQHIQDILNGGPSKRQTNGCLNGYTPSRK

--------------------------------------------------------------
>53457_53457_8_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367886_UCK2_chr1_165859441_ENST00000372212_length(transcript)=1250nt_BP=159nt
ATGCCCTGGAGGGGAAGGCGCTTCCGGCTCTGCAGACGCAAGATGGCTGTCCTCTCTAAGGAATATGGTTTTGTGCTTCTAACTGGTGCT
GCCAGCTTTATAATGGTGGCCCACCTAGCCATCAATGTTTCCAAGGCCCGCAAGAAGTACAAAGTGGAGTCTTCCGTGTGTGCTAAGATC
GTGCAGCTCCTGGGGCAGAATGAGGTGGACTATCGCCAGAAGCAGGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCG
GAGCAGAAGGCCAAAGCCCTGAAGGGCCAGTTCAACTTTGACCACCCGGATGCCTTTGACAATGAACTCATTCTCAAAACACTCAAAGAA
ATCACTGAAGGGAAAACAGTCCAGATCCCCGTGTATGACTTTGTCTCCCATTCCCGTATTAAGGGACATCAGCGAGAGAGGCAGGGATCT
TGAGCAGATTTTATCTCAGTACATTACGTTCGTCAAGCCTGCCTTTGAGGAATTCTGCTTGCCAACAAAGAAGTATGCTGATGTGATCAT
CCCTAGAGGTGCAGATAATCTGGTGGCCATCAACCTCATCGTGCAGCACATCCAGGACATCCTGAATGGAGGGCCCTCCAAACGGCAGAC
CAATGGCTGTCTCAACGGCTACACCCCTTCACGCAAGAGGCAGGCATCGGAGTCCAGCAGCAGGCCGCATTGACCCGTCTCCATCGGACC
CCAGCCCCTATCTCCAAGAGACAGAGGAGGGGTCAGGAGGCACTGCTCATCTGTACATACTGTTTCCTATGACATTACTGTATTTAAGAA
AACACCATGGAGATGAAATGCCTTTGATTTTTTTTTTCTTTTTGTACTTTGGAACGACAAAATGAAACAGAACTTGACCCTGAGCTTAAA
TAACAAAACTGTGCCAACTACTACTGGTGATGCCTAATTATGAATCCAACGTGTAACCAGTTATAAATACATATATATATAAAAAAGGAT
CTATTTTTGTGTAAATGTACAAATACTGTAAAGCTGTTTGCCATAAGTATTTTGCAGGAGGGTCTGTACTTGAGTGTTTTAGGACTGGAG
CTGGAATTTCACCAAGGGGAAATTGCCTGTTGTGTCCCAGGGTGGGGAGGCTCGGGCATCTGTGAGAGACAGGGAGGGTGGCTAAGGTCC

>53457_53457_8_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367886_UCK2_chr1_165859441_ENST00000372212_length(amino acids)=150AA_BP=0
MPWRGRRFRLCRRKMAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTS

--------------------------------------------------------------
>53457_53457_9_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367888_UCK2_chr1_165859441_ENST00000367879_length(transcript)=1178nt_BP=205nt
AGCCCCGCCCCAGGCGAGGGCGCCGCACCCACACCGCGCTGCGCAGTTTTGTTCTGCTCCAGCTGTTCGAAGGTGATCCAGACGCAAGAT
GGCTGTCCTCTCTAAGGAATATGGTTTTGTGCTTCTAACTGGTGCTGCCAGCTTTATAATGGTGGCCCACCTAGCCATCAATGTTTCCAA
GGCCCGCAAGAAGTACAAAGTGGAGTCTTCCGTGTGTGCTAAGATCGTGCAGCTCCTGGGGCAGAATGAGGTGGACTATCGCCAGAAGCA
GGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCGGAGCAGAAGGCCAAAGCCCTGAAGGGCCAGTTCAACTTTGACCA
CCCGGATGCCTTTGACAATGAACTCATTCTCAAAACACTCAAAGAAATCACTGAAGGGAAAACAGTCCAGATCCCCGTGTATGACTTTGT
CTCCCATTCCCGGAAGGAGGAGACAGTTACTGTCTATCCCGCAGACGTGGTGCTCTTTGAAGGGATCCTGGCCTTCTACTCCCAGGAGGT
ACGAGACCTGTTCCAGATGAAGCTTTTTGTGGATACAGATGCGGACACCCGGCTCTCACGCAGAGTATTAAGGGACATCAGCGAGAGAGG
CAGGGATCTTGAGCAGATTTTATCTCAGTACATTACGTTCGTCAAGCCTGCCTTTGAGGAATTCTGCTTGCCAACAAAGAAGTATGCTGA
TGTGATCATCCCTAGAGGTGCAGATAATCTGGTGGCCATCAACCTCATCGTGCAGCACATCCAGGACATCCTGAATGGAGGGCCCTCCAA
ACGGCAGACCAATGGCTGTCTCAACGGCTACACCCCTTCACGCAAGAGGCAGGCATCGGAGTCCAGCAGCAGGCCGCATTGACCCGTCTC
CATCGGACCCCAGCCCCTATCTCCAAGAGACAGAGGAGGGGTCAGGAGGCACTGCTCATCTGTACATACTGTTTCCTATGACATTACTGT
ATTTAAGAAAACACCATGGAGATGAAATGCCTTTGATTTTTTTTTTCTTTTTGTACTTTGGAACGACAAAATGAAACAGAACTTGACCCT
GAGCTTAAATAACAAAACTGTGCCAACTACTACTGGTGATGCCTAATTATGAATCCAACGTGTAACCAGTTATAAATACATATATATATA

>53457_53457_9_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367888_UCK2_chr1_165859441_ENST00000367879_length(amino acids)=267AA_BP=0
MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFD
HPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISER

--------------------------------------------------------------
>53457_53457_10_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367888_UCK2_chr1_165859441_ENST00000372212_length(transcript)=1296nt_BP=205nt
AGCCCCGCCCCAGGCGAGGGCGCCGCACCCACACCGCGCTGCGCAGTTTTGTTCTGCTCCAGCTGTTCGAAGGTGATCCAGACGCAAGAT
GGCTGTCCTCTCTAAGGAATATGGTTTTGTGCTTCTAACTGGTGCTGCCAGCTTTATAATGGTGGCCCACCTAGCCATCAATGTTTCCAA
GGCCCGCAAGAAGTACAAAGTGGAGTCTTCCGTGTGTGCTAAGATCGTGCAGCTCCTGGGGCAGAATGAGGTGGACTATCGCCAGAAGCA
GGTGGTCATCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCGGAGCAGAAGGCCAAAGCCCTGAAGGGCCAGTTCAACTTTGACCA
CCCGGATGCCTTTGACAATGAACTCATTCTCAAAACACTCAAAGAAATCACTGAAGGGAAAACAGTCCAGATCCCCGTGTATGACTTTGT
CTCCCATTCCCGTATTAAGGGACATCAGCGAGAGAGGCAGGGATCTTGAGCAGATTTTATCTCAGTACATTACGTTCGTCAAGCCTGCCT
TTGAGGAATTCTGCTTGCCAACAAAGAAGTATGCTGATGTGATCATCCCTAGAGGTGCAGATAATCTGGTGGCCATCAACCTCATCGTGC
AGCACATCCAGGACATCCTGAATGGAGGGCCCTCCAAACGGCAGACCAATGGCTGTCTCAACGGCTACACCCCTTCACGCAAGAGGCAGG
CATCGGAGTCCAGCAGCAGGCCGCATTGACCCGTCTCCATCGGACCCCAGCCCCTATCTCCAAGAGACAGAGGAGGGGTCAGGAGGCACT
GCTCATCTGTACATACTGTTTCCTATGACATTACTGTATTTAAGAAAACACCATGGAGATGAAATGCCTTTGATTTTTTTTTTCTTTTTG
TACTTTGGAACGACAAAATGAAACAGAACTTGACCCTGAGCTTAAATAACAAAACTGTGCCAACTACTACTGGTGATGCCTAATTATGAA
TCCAACGTGTAACCAGTTATAAATACATATATATATAAAAAAGGATCTATTTTTGTGTAAATGTACAAATACTGTAAAGCTGTTTGCCAT
AAGTATTTTGCAGGAGGGTCTGTACTTGAGTGTTTTAGGACTGGAGCTGGAATTTCACCAAGGGGAAATTGCCTGTTGTGTCCCAGGGTG
GGGAGGCTCGGGCATCTGTGAGAGACAGGGAGGGTGGCTAAGGTCCAGTTGCTTTTGAGTGCCCCGTGGAACTTGATGGGAATGGGGTTG

>53457_53457_10_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367888_UCK2_chr1_165859441_ENST00000372212_length(amino acids)=136AA_BP=0
MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFD

--------------------------------------------------------------
>53457_53457_11_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367889_UCK2_chr1_165859441_ENST00000367879_length(transcript)=1530nt_BP=557nt
ATGCCCGTGCTTCGCCCTTACAGCAGAGCGCCTAAAACCGCTACGGTGGCTCTGCTGGGGACAAATTATTCACGTCCCACTGTTCTGCAA
ACCCAATCCGGGAGGTATGACCTGGCTGGGACAGTTTAGGAAGATGGCCACGAAGGCACCTGGGGGAGTAGATATATGTTTTTGAGAATG
AGAGGAGTAAATCGCTGGACGACCATGAGCAGGAAGAAAATTAGGCCTCCACCTCCCAACCAGTGGCCCTGAGTTGGCAACTTAGACAGC
GCGCGCCAGCGCCAGGAGCCCCGCCTTGGGGGCGTGGCCGCGCGCTGGTCGGCTGGGGCGGGGCCTGCTTCTGGCCTCATCTAGCCCCGC
CCCAGGCGAGGGCGCCGCACCCACACCGCGCTGCGCAGTTTTGTTCTGCTCCAGCTGTTCGAAGGTGATCCAGACGCAAGATGGCTGTCC
TCTCTAAGGAATATGGTTTTGTGCTTCTAACTGGTGCTGCCAGCTTTATAATGGTGGCCCACCTAGCCATCAATGTTTCCAAGGCCCGCA
AGAAGTACAAAGTGGAGTCTTCCGTGTGTGCTAAGATCGTGCAGCTCCTGGGGCAGAATGAGGTGGACTATCGCCAGAAGCAGGTGGTCA
TCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCGGAGCAGAAGGCCAAAGCCCTGAAGGGCCAGTTCAACTTTGACCACCCGGATG
CCTTTGACAATGAACTCATTCTCAAAACACTCAAAGAAATCACTGAAGGGAAAACAGTCCAGATCCCCGTGTATGACTTTGTCTCCCATT
CCCGGAAGGAGGAGACAGTTACTGTCTATCCCGCAGACGTGGTGCTCTTTGAAGGGATCCTGGCCTTCTACTCCCAGGAGGTACGAGACC
TGTTCCAGATGAAGCTTTTTGTGGATACAGATGCGGACACCCGGCTCTCACGCAGAGTATTAAGGGACATCAGCGAGAGAGGCAGGGATC
TTGAGCAGATTTTATCTCAGTACATTACGTTCGTCAAGCCTGCCTTTGAGGAATTCTGCTTGCCAACAAAGAAGTATGCTGATGTGATCA
TCCCTAGAGGTGCAGATAATCTGGTGGCCATCAACCTCATCGTGCAGCACATCCAGGACATCCTGAATGGAGGGCCCTCCAAACGGCAGA
CCAATGGCTGTCTCAACGGCTACACCCCTTCACGCAAGAGGCAGGCATCGGAGTCCAGCAGCAGGCCGCATTGACCCGTCTCCATCGGAC
CCCAGCCCCTATCTCCAAGAGACAGAGGAGGGGTCAGGAGGCACTGCTCATCTGTACATACTGTTTCCTATGACATTACTGTATTTAAGA
AAACACCATGGAGATGAAATGCCTTTGATTTTTTTTTTCTTTTTGTACTTTGGAACGACAAAATGAAACAGAACTTGACCCTGAGCTTAA
ATAACAAAACTGTGCCAACTACTACTGGTGATGCCTAATTATGAATCCAACGTGTAACCAGTTATAAATACATATATATATAAAAAAGGA

>53457_53457_11_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367889_UCK2_chr1_165859441_ENST00000367879_length(amino acids)=267AA_BP=0
MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFD
HPDAFDNELILKTLKEITEGKTVQIPVYDFVSHSRKEETVTVYPADVVLFEGILAFYSQEVRDLFQMKLFVDTDADTRLSRRVLRDISER

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>53457_53457_12_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367889_UCK2_chr1_165859441_ENST00000372212_length(transcript)=1648nt_BP=557nt
ATGCCCGTGCTTCGCCCTTACAGCAGAGCGCCTAAAACCGCTACGGTGGCTCTGCTGGGGACAAATTATTCACGTCCCACTGTTCTGCAA
ACCCAATCCGGGAGGTATGACCTGGCTGGGACAGTTTAGGAAGATGGCCACGAAGGCACCTGGGGGAGTAGATATATGTTTTTGAGAATG
AGAGGAGTAAATCGCTGGACGACCATGAGCAGGAAGAAAATTAGGCCTCCACCTCCCAACCAGTGGCCCTGAGTTGGCAACTTAGACAGC
GCGCGCCAGCGCCAGGAGCCCCGCCTTGGGGGCGTGGCCGCGCGCTGGTCGGCTGGGGCGGGGCCTGCTTCTGGCCTCATCTAGCCCCGC
CCCAGGCGAGGGCGCCGCACCCACACCGCGCTGCGCAGTTTTGTTCTGCTCCAGCTGTTCGAAGGTGATCCAGACGCAAGATGGCTGTCC
TCTCTAAGGAATATGGTTTTGTGCTTCTAACTGGTGCTGCCAGCTTTATAATGGTGGCCCACCTAGCCATCAATGTTTCCAAGGCCCGCA
AGAAGTACAAAGTGGAGTCTTCCGTGTGTGCTAAGATCGTGCAGCTCCTGGGGCAGAATGAGGTGGACTATCGCCAGAAGCAGGTGGTCA
TCCTGAGCCAGGATAGCTTCTACCGTGTCCTTACCTCGGAGCAGAAGGCCAAAGCCCTGAAGGGCCAGTTCAACTTTGACCACCCGGATG
CCTTTGACAATGAACTCATTCTCAAAACACTCAAAGAAATCACTGAAGGGAAAACAGTCCAGATCCCCGTGTATGACTTTGTCTCCCATT
CCCGTATTAAGGGACATCAGCGAGAGAGGCAGGGATCTTGAGCAGATTTTATCTCAGTACATTACGTTCGTCAAGCCTGCCTTTGAGGAA
TTCTGCTTGCCAACAAAGAAGTATGCTGATGTGATCATCCCTAGAGGTGCAGATAATCTGGTGGCCATCAACCTCATCGTGCAGCACATC
CAGGACATCCTGAATGGAGGGCCCTCCAAACGGCAGACCAATGGCTGTCTCAACGGCTACACCCCTTCACGCAAGAGGCAGGCATCGGAG
TCCAGCAGCAGGCCGCATTGACCCGTCTCCATCGGACCCCAGCCCCTATCTCCAAGAGACAGAGGAGGGGTCAGGAGGCACTGCTCATCT
GTACATACTGTTTCCTATGACATTACTGTATTTAAGAAAACACCATGGAGATGAAATGCCTTTGATTTTTTTTTTCTTTTTGTACTTTGG
AACGACAAAATGAAACAGAACTTGACCCTGAGCTTAAATAACAAAACTGTGCCAACTACTACTGGTGATGCCTAATTATGAATCCAACGT
GTAACCAGTTATAAATACATATATATATAAAAAAGGATCTATTTTTGTGTAAATGTACAAATACTGTAAAGCTGTTTGCCATAAGTATTT
TGCAGGAGGGTCTGTACTTGAGTGTTTTAGGACTGGAGCTGGAATTTCACCAAGGGGAAATTGCCTGTTGTGTCCCAGGGTGGGGAGGCT
CGGGCATCTGTGAGAGACAGGGAGGGTGGCTAAGGTCCAGTTGCTTTTGAGTGCCCCGTGGAACTTGATGGGAATGGGGTTGGAAAACCT

>53457_53457_12_MGST3-UCK2_MGST3_chr1_165619201_ENST00000367889_UCK2_chr1_165859441_ENST00000372212_length(amino acids)=136AA_BP=0
MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVESSVCAKIVQLLGQNEVDYRQKQVVILSQDSFYRVLTSEQKAKALKGQFNFD

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for MGST3-UCK2

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for MGST3-UCK2

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for MGST3-UCK2

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source