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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Diseases

Fusion gene:MICU1-ARHGAP22 (FusionGDB2 ID:53566)

Fusion Gene Summary for MICU1-ARHGAP22

check button Fusion gene summary
Fusion gene informationFusion gene name: MICU1-ARHGAP22
Fusion gene ID: 53566
HgeneTgene
Gene symbol

MICU1

ARHGAP22

Gene ID

10367

58504

Gene namemitochondrial calcium uptake 1Rho GTPase activating protein 22
SynonymsCALC|CBARA1|EFHA3|MPXPS|ara CALCRhoGAP2|RhoGap22
Cytomap

10q22.1

10q11.22-q11.23

Type of geneprotein-codingprotein-coding
Descriptioncalcium uptake protein 1, mitochondrialatopy-related autoantigen CALCcalcium-binding atopy-related autoantigen 1rho GTPase-activating protein 22rho-type GTPase-activating protein 22
Modification date2020031320200322
UniProtAcc

Q9BPX6

Q7Z5H3

Ensembl transtripts involved in fusion geneENST00000361114, ENST00000398761, 
ENST00000398763, ENST00000401998, 
ENST00000418483, ENST00000604025, 
ENST00000477708, ENST00000491108, 
ENST00000249601, ENST00000374170, 
ENST00000374172, ENST00000417912, 
ENST00000435790, ENST00000417247, 
Fusion gene scores* DoF score13 X 11 X 8=11441 X 1 X 1=1
# samples 172
** MAII scorelog2(17/1144*10)=-2.75048040064069
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/1*10)=4.32192809488736
Context

PubMed: MICU1 [Title/Abstract] AND ARHGAP22 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMICU1(74167687)-ARHGAP22(49654662), # samples:3
Anticipated loss of major functional domain due to fusion event.MICU1-ARHGAP22 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
MICU1-ARHGAP22 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMICU1

GO:0006851

mitochondrial calcium ion transmembrane transport

24560927

HgeneMICU1

GO:0051260

protein homooligomerization

24514027

HgeneMICU1

GO:0051561

positive regulation of mitochondrial calcium ion concentration

24560927

HgeneMICU1

GO:0070509

calcium ion import

20693986

TgeneARHGAP22

GO:0099175

regulation of postsynapse organization

21926414


check buttonFusion gene breakpoints across MICU1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARHGAP22 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A0HU-01AMICU1chr10

74167687

-ARHGAP22chr10

49654662

-
ChimerDB4BRCATCGA-BH-A0HUMICU1chr10

74167686

-ARHGAP22chr10

49654662

-


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Fusion Gene ORF analysis for MICU1-ARHGAP22

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000361114ENST00000477708MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000361114ENST00000477708MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000361114ENST00000491108MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000361114ENST00000491108MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000398761ENST00000477708MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000398761ENST00000477708MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000398761ENST00000491108MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000398761ENST00000491108MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000398763ENST00000477708MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000398763ENST00000477708MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000398763ENST00000491108MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000398763ENST00000491108MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000401998ENST00000477708MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000401998ENST00000477708MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000401998ENST00000491108MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000401998ENST00000491108MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000418483ENST00000477708MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000418483ENST00000477708MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000418483ENST00000491108MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
5CDS-intronENST00000418483ENST00000491108MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000361114ENST00000249601MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000361114ENST00000249601MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000361114ENST00000374170MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000361114ENST00000374170MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000361114ENST00000374172MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000361114ENST00000374172MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000361114ENST00000417912MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000361114ENST00000417912MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000361114ENST00000435790MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000361114ENST00000435790MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398761ENST00000249601MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398761ENST00000249601MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398761ENST00000374170MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398761ENST00000374170MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398761ENST00000374172MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398761ENST00000374172MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398761ENST00000417912MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398761ENST00000417912MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398761ENST00000435790MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398761ENST00000435790MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398763ENST00000374170MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398763ENST00000374170MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398763ENST00000374172MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398763ENST00000374172MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398763ENST00000417247MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000398763ENST00000417247MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000401998ENST00000249601MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000401998ENST00000249601MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000401998ENST00000374170MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000401998ENST00000374170MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000401998ENST00000374172MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000401998ENST00000374172MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000401998ENST00000417912MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000401998ENST00000417912MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000401998ENST00000435790MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000401998ENST00000435790MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000418483ENST00000374170MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000418483ENST00000374170MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000418483ENST00000374172MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000418483ENST00000374172MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000418483ENST00000417247MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
Frame-shiftENST00000418483ENST00000417247MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
In-frameENST00000361114ENST00000417247MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
In-frameENST00000361114ENST00000417247MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
In-frameENST00000398761ENST00000417247MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
In-frameENST00000398761ENST00000417247MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
In-frameENST00000398763ENST00000249601MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
In-frameENST00000398763ENST00000249601MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
In-frameENST00000398763ENST00000417912MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
In-frameENST00000398763ENST00000417912MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
In-frameENST00000398763ENST00000435790MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
In-frameENST00000398763ENST00000435790MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
In-frameENST00000401998ENST00000417247MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
In-frameENST00000401998ENST00000417247MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
In-frameENST00000418483ENST00000249601MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
In-frameENST00000418483ENST00000249601MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
In-frameENST00000418483ENST00000417912MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
In-frameENST00000418483ENST00000417912MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
In-frameENST00000418483ENST00000435790MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
In-frameENST00000418483ENST00000435790MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000249601MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000249601MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000374170MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000374170MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000374172MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000374172MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000417247MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000417247MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000417912MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000417912MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000435790MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
intron-3CDSENST00000604025ENST00000435790MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
intron-intronENST00000604025ENST00000477708MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
intron-intronENST00000604025ENST00000477708MICU1chr10

74167686

-ARHGAP22chr10

49654662

-
intron-intronENST00000604025ENST00000491108MICU1chr10

74167687

-ARHGAP22chr10

49654662

-
intron-intronENST00000604025ENST00000491108MICU1chr10

74167686

-ARHGAP22chr10

49654662

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000401998MICU1chr1074167687-ENST00000417247ARHGAP22chr1049654662-18341251621276404
ENST00000361114MICU1chr1074167687-ENST00000417247ARHGAP22chr1049654662-18601277881302404
ENST00000398761MICU1chr1074167687-ENST00000417247ARHGAP22chr1049654662-190213191241344406
ENST00000418483MICU1chr1074167687-ENST00000249601ARHGAP22chr1049654662-126668082705207
ENST00000418483MICU1chr1074167687-ENST00000435790ARHGAP22chr1049654662-105868082705207
ENST00000418483MICU1chr1074167687-ENST00000417912ARHGAP22chr1049654662-96068082705207
ENST00000398763MICU1chr1074167687-ENST00000249601ARHGAP22chr1049654662-1475889303914203
ENST00000398763MICU1chr1074167687-ENST00000435790ARHGAP22chr1049654662-1267889303914203
ENST00000398763MICU1chr1074167687-ENST00000417912ARHGAP22chr1049654662-1169889303914203
ENST00000401998MICU1chr1074167686-ENST00000417247ARHGAP22chr1049654662-18341251621276404
ENST00000361114MICU1chr1074167686-ENST00000417247ARHGAP22chr1049654662-18601277881302404
ENST00000398761MICU1chr1074167686-ENST00000417247ARHGAP22chr1049654662-190213191241344406
ENST00000418483MICU1chr1074167686-ENST00000249601ARHGAP22chr1049654662-126668082705207
ENST00000418483MICU1chr1074167686-ENST00000435790ARHGAP22chr1049654662-105868082705207
ENST00000418483MICU1chr1074167686-ENST00000417912ARHGAP22chr1049654662-96068082705207
ENST00000398763MICU1chr1074167686-ENST00000249601ARHGAP22chr1049654662-1475889303914203
ENST00000398763MICU1chr1074167686-ENST00000435790ARHGAP22chr1049654662-1267889303914203
ENST00000398763MICU1chr1074167686-ENST00000417912ARHGAP22chr1049654662-1169889303914203

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000401998ENST00000417247MICU1chr1074167687-ARHGAP22chr1049654662-0.0006807910.9993192
ENST00000361114ENST00000417247MICU1chr1074167687-ARHGAP22chr1049654662-0.0006402670.9993598
ENST00000398761ENST00000417247MICU1chr1074167687-ARHGAP22chr1049654662-0.0006643430.9993356
ENST00000418483ENST00000249601MICU1chr1074167687-ARHGAP22chr1049654662-0.0062772660.99372274
ENST00000418483ENST00000435790MICU1chr1074167687-ARHGAP22chr1049654662-0.0059422410.9940578
ENST00000418483ENST00000417912MICU1chr1074167687-ARHGAP22chr1049654662-0.0039514190.9960486
ENST00000398763ENST00000249601MICU1chr1074167687-ARHGAP22chr1049654662-0.0066618850.9933381
ENST00000398763ENST00000435790MICU1chr1074167687-ARHGAP22chr1049654662-0.0058814340.9941186
ENST00000398763ENST00000417912MICU1chr1074167687-ARHGAP22chr1049654662-0.0045411950.99545884
ENST00000401998ENST00000417247MICU1chr1074167686-ARHGAP22chr1049654662-0.0006807910.9993192
ENST00000361114ENST00000417247MICU1chr1074167686-ARHGAP22chr1049654662-0.0006402670.9993598
ENST00000398761ENST00000417247MICU1chr1074167686-ARHGAP22chr1049654662-0.0006643430.9993356
ENST00000418483ENST00000249601MICU1chr1074167686-ARHGAP22chr1049654662-0.0062772660.99372274
ENST00000418483ENST00000435790MICU1chr1074167686-ARHGAP22chr1049654662-0.0059422410.9940578
ENST00000418483ENST00000417912MICU1chr1074167686-ARHGAP22chr1049654662-0.0039514190.9960486
ENST00000398763ENST00000249601MICU1chr1074167686-ARHGAP22chr1049654662-0.0066618850.9933381
ENST00000398763ENST00000435790MICU1chr1074167686-ARHGAP22chr1049654662-0.0058814340.9941186
ENST00000398763ENST00000417912MICU1chr1074167686-ARHGAP22chr1049654662-0.0045411950.99545884

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Fusion Genomic Features for MICU1-ARHGAP22


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MICU1-ARHGAP22


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:74167687/chr10:49654662)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MICU1

Q9BPX6

ARHGAP22

Q7Z5H3

FUNCTION: Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains (PubMed:20693986, PubMed:23101630, PubMed:23747253, PubMed:24313810, PubMed:24332854, PubMed:24503055, PubMed:24560927, PubMed:26341627, PubMed:26903221, PubMed:27099988). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulates and inhibits MCU activity, depending on the concentration of calcium. MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptake (PubMed:26903221). Acts as a gatekeeper of MCU at low concentration of calcium, preventing channel opening (PubMed:26903221). Enhances MCU opening at high calcium concentration, allowing a rapid response of mitochondria to calcium signals generated in the cytoplasm (PubMed:24560927, PubMed:26903221). Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake (PubMed:22904319). Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG (PubMed:16002733). {ECO:0000269|PubMed:16002733, ECO:0000269|PubMed:20693986, ECO:0000269|PubMed:22904319, ECO:0000269|PubMed:23101630, ECO:0000269|PubMed:23747253, ECO:0000269|PubMed:24313810, ECO:0000269|PubMed:24332854, ECO:0000269|PubMed:24503055, ECO:0000269|PubMed:24560927, ECO:0000269|PubMed:26341627, ECO:0000269|PubMed:26903221, ECO:0000269|PubMed:27099988}.FUNCTION: Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMICU1chr10:74167686chr10:49654662ENST00000361114-1012231_242393477.0Calcium binding1
HgeneMICU1chr10:74167687chr10:49654662ENST00000361114-1012231_242393477.0Calcium binding1
HgeneMICU1chr10:74167686chr10:49654662ENST00000361114-1012218_253393477.0DomainEF-hand 1
HgeneMICU1chr10:74167687chr10:49654662ENST00000361114-1012218_253393477.0DomainEF-hand 1
HgeneMICU1chr10:74167686chr10:49654662ENST00000361114-101299_110393477.0RegionPolybasic region
HgeneMICU1chr10:74167686chr10:49654662ENST00000398763-7999_110195279.0RegionPolybasic region
HgeneMICU1chr10:74167686chr10:49654662ENST00000418483-5799_110195279.0RegionPolybasic region
HgeneMICU1chr10:74167687chr10:49654662ENST00000361114-101299_110393477.0RegionPolybasic region
HgeneMICU1chr10:74167687chr10:49654662ENST00000398763-7999_110195279.0RegionPolybasic region
HgeneMICU1chr10:74167687chr10:49654662ENST00000418483-5799_110195279.0RegionPolybasic region
HgeneMICU1chr10:74167686chr10:49654662ENST00000361114-101234_52393477.0TransmembraneHelical
HgeneMICU1chr10:74167686chr10:49654662ENST00000398763-7934_52195279.0TransmembraneHelical
HgeneMICU1chr10:74167686chr10:49654662ENST00000418483-5734_52195279.0TransmembraneHelical
HgeneMICU1chr10:74167687chr10:49654662ENST00000361114-101234_52393477.0TransmembraneHelical
HgeneMICU1chr10:74167687chr10:49654662ENST00000398763-7934_52195279.0TransmembraneHelical
HgeneMICU1chr10:74167687chr10:49654662ENST00000418483-5734_52195279.0TransmembraneHelical
TgeneARHGAP22chr10:74167686chr10:49654662ENST0000041724768590_687532609.0Coiled coilOntology_term=ECO:0000255
TgeneARHGAP22chr10:74167687chr10:49654662ENST0000041724768590_687532609.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMICU1chr10:74167686chr10:49654662ENST00000361114-1012421_432393477.0Calcium binding2
HgeneMICU1chr10:74167686chr10:49654662ENST00000398763-79231_242195279.0Calcium binding1
HgeneMICU1chr10:74167686chr10:49654662ENST00000398763-79421_432195279.0Calcium binding2
HgeneMICU1chr10:74167686chr10:49654662ENST00000418483-57231_242195279.0Calcium binding1
HgeneMICU1chr10:74167686chr10:49654662ENST00000418483-57421_432195279.0Calcium binding2
HgeneMICU1chr10:74167687chr10:49654662ENST00000361114-1012421_432393477.0Calcium binding2
HgeneMICU1chr10:74167687chr10:49654662ENST00000398763-79231_242195279.0Calcium binding1
HgeneMICU1chr10:74167687chr10:49654662ENST00000398763-79421_432195279.0Calcium binding2
HgeneMICU1chr10:74167687chr10:49654662ENST00000418483-57231_242195279.0Calcium binding1
HgeneMICU1chr10:74167687chr10:49654662ENST00000418483-57421_432195279.0Calcium binding2
HgeneMICU1chr10:74167686chr10:49654662ENST00000361114-1012408_443393477.0DomainEF-hand 2
HgeneMICU1chr10:74167686chr10:49654662ENST00000398763-79218_253195279.0DomainEF-hand 1
HgeneMICU1chr10:74167686chr10:49654662ENST00000398763-79408_443195279.0DomainEF-hand 2
HgeneMICU1chr10:74167686chr10:49654662ENST00000418483-57218_253195279.0DomainEF-hand 1
HgeneMICU1chr10:74167686chr10:49654662ENST00000418483-57408_443195279.0DomainEF-hand 2
HgeneMICU1chr10:74167687chr10:49654662ENST00000361114-1012408_443393477.0DomainEF-hand 2
HgeneMICU1chr10:74167687chr10:49654662ENST00000398763-79218_253195279.0DomainEF-hand 1
HgeneMICU1chr10:74167687chr10:49654662ENST00000398763-79408_443195279.0DomainEF-hand 2
HgeneMICU1chr10:74167687chr10:49654662ENST00000418483-57218_253195279.0DomainEF-hand 1
HgeneMICU1chr10:74167687chr10:49654662ENST00000418483-57408_443195279.0DomainEF-hand 2
HgeneMICU1chr10:74167686chr10:49654662ENST00000361114-1012455_465393477.0RegionC-helix region
HgeneMICU1chr10:74167686chr10:49654662ENST00000398763-79455_465195279.0RegionC-helix region
HgeneMICU1chr10:74167686chr10:49654662ENST00000418483-57455_465195279.0RegionC-helix region
HgeneMICU1chr10:74167687chr10:49654662ENST00000361114-1012455_465393477.0RegionC-helix region
HgeneMICU1chr10:74167687chr10:49654662ENST00000398763-79455_465195279.0RegionC-helix region
HgeneMICU1chr10:74167687chr10:49654662ENST00000418483-57455_465195279.0RegionC-helix region
HgeneMICU1chr10:74167686chr10:49654662ENST00000361114-101253_476393477.0Topological domainMitochondrial intermembrane
HgeneMICU1chr10:74167686chr10:49654662ENST00000398763-7953_476195279.0Topological domainMitochondrial intermembrane
HgeneMICU1chr10:74167686chr10:49654662ENST00000418483-5753_476195279.0Topological domainMitochondrial intermembrane
HgeneMICU1chr10:74167687chr10:49654662ENST00000361114-101253_476393477.0Topological domainMitochondrial intermembrane
HgeneMICU1chr10:74167687chr10:49654662ENST00000398763-7953_476195279.0Topological domainMitochondrial intermembrane
HgeneMICU1chr10:74167687chr10:49654662ENST00000418483-5753_476195279.0Topological domainMitochondrial intermembrane
TgeneARHGAP22chr10:74167686chr10:49654662ENST00000249601810590_687622699.0Coiled coilOntology_term=ECO:0000255
TgeneARHGAP22chr10:74167686chr10:49654662ENST00000417912810590_687638715.0Coiled coilOntology_term=ECO:0000255
TgeneARHGAP22chr10:74167686chr10:49654662ENST00000435790810590_687628705.0Coiled coilOntology_term=ECO:0000255
TgeneARHGAP22chr10:74167687chr10:49654662ENST00000249601810590_687622699.0Coiled coilOntology_term=ECO:0000255
TgeneARHGAP22chr10:74167687chr10:49654662ENST00000417912810590_687638715.0Coiled coilOntology_term=ECO:0000255
TgeneARHGAP22chr10:74167687chr10:49654662ENST00000435790810590_687628705.0Coiled coilOntology_term=ECO:0000255
TgeneARHGAP22chr10:74167686chr10:49654662ENST00000249601810427_587622699.0Compositional biasNote=Ser-rich
TgeneARHGAP22chr10:74167686chr10:49654662ENST0000041724768427_587532609.0Compositional biasNote=Ser-rich
TgeneARHGAP22chr10:74167686chr10:49654662ENST00000417912810427_587638715.0Compositional biasNote=Ser-rich
TgeneARHGAP22chr10:74167686chr10:49654662ENST00000435790810427_587628705.0Compositional biasNote=Ser-rich
TgeneARHGAP22chr10:74167687chr10:49654662ENST00000249601810427_587622699.0Compositional biasNote=Ser-rich
TgeneARHGAP22chr10:74167687chr10:49654662ENST0000041724768427_587532609.0Compositional biasNote=Ser-rich
TgeneARHGAP22chr10:74167687chr10:49654662ENST00000417912810427_587638715.0Compositional biasNote=Ser-rich
TgeneARHGAP22chr10:74167687chr10:49654662ENST00000435790810427_587628705.0Compositional biasNote=Ser-rich
TgeneARHGAP22chr10:74167686chr10:49654662ENST00000249601810155_349622699.0DomainRho-GAP
TgeneARHGAP22chr10:74167686chr10:49654662ENST0000024960181037_145622699.0DomainPH
TgeneARHGAP22chr10:74167686chr10:49654662ENST0000041724768155_349532609.0DomainRho-GAP
TgeneARHGAP22chr10:74167686chr10:49654662ENST000004172476837_145532609.0DomainPH
TgeneARHGAP22chr10:74167686chr10:49654662ENST00000417912810155_349638715.0DomainRho-GAP
TgeneARHGAP22chr10:74167686chr10:49654662ENST0000041791281037_145638715.0DomainPH
TgeneARHGAP22chr10:74167686chr10:49654662ENST00000435790810155_349628705.0DomainRho-GAP
TgeneARHGAP22chr10:74167686chr10:49654662ENST0000043579081037_145628705.0DomainPH
TgeneARHGAP22chr10:74167687chr10:49654662ENST00000249601810155_349622699.0DomainRho-GAP
TgeneARHGAP22chr10:74167687chr10:49654662ENST0000024960181037_145622699.0DomainPH
TgeneARHGAP22chr10:74167687chr10:49654662ENST0000041724768155_349532609.0DomainRho-GAP
TgeneARHGAP22chr10:74167687chr10:49654662ENST000004172476837_145532609.0DomainPH
TgeneARHGAP22chr10:74167687chr10:49654662ENST00000417912810155_349638715.0DomainRho-GAP
TgeneARHGAP22chr10:74167687chr10:49654662ENST0000041791281037_145638715.0DomainPH
TgeneARHGAP22chr10:74167687chr10:49654662ENST00000435790810155_349628705.0DomainRho-GAP
TgeneARHGAP22chr10:74167687chr10:49654662ENST0000043579081037_145628705.0DomainPH


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Fusion Gene Sequence for MICU1-ARHGAP22


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>53566_53566_1_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000361114_ARHGAP22_chr10_49654662_ENST00000417247_length(transcript)=1860nt_BP=1277nt
GGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTT
GGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCA
GATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGA
ATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAA
GACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGAT
TCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGAC
ACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGG
AAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGA
CTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGT
AGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAA
CACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGA
ATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGTTTGAACGCCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGG
TGGCATGCTACTTGCCTACAGTGGGGTGCAGTCCAAGAAGCTGACCGCCATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGG
TCTGACATTTCAGGAGGTGGAGAACTTCTTTACTTTCCTAAAGAACATTAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGG
AGCATCTCTTGATAAAGAATCGAAGAAGGGAGTGCTGACCTGAGAAAACGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAA
AAATACATCATGCTGGAAATAAAGCTGCGGAACTCTGAACGGGCGCGGGAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATG
GAGGAGTTTTTTTCGACCCTAGGAAGCTTGACTGTTGGGGCAAAAGGTGCCAGGGCCCCAAAGTAAAAGGAATGGCAGAGCTCACTTCTG
TACCACGTCTGCTGGTCTCCAGCCTTGTATGGAGTTAGAAGCGTCTGTATCTCTGGAGCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAG
AGAGATCCTGATACCTCTGTGGGGACTGTGGGGACTTTTGGGACCCCACACACTCCAGGTGGGATCAGATGCTGCTCCAACCATGCAGTT
CCTGGTGAGGGTCAGAAGGGGACGGTACCAAGAGTAGCGCTTAGCCCTTACCCAGGAAATATCCTTCATGGCCACAGAAATGGAGGGCGC

>53566_53566_1_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000361114_ARHGAP22_chr10_49654662_ENST00000417247_length(amino acids)=404AA_BP=
MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK
KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD
GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTG
NTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGK

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>53566_53566_2_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000398761_ARHGAP22_chr10_49654662_ENST00000417247_length(transcript)=1902nt_BP=1319nt
AGGCCCAGCGGCTAGGAGAGTCACGTGAGAGTGGGCGGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGG
GCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGG
TTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGC
AAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAA
TAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATT
CAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGT
CATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTT
GGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAATAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTAT
ATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGA
AATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAATTAGCATCATTCGCTCCCAAAC
CAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGG
AGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGTTTGAACG
CCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTGCAGTCCAAGAAGCTGACCGC
CATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTCTTTACTTTCCTAAAGAACAT
TAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAGGGAGTGCTGACCTGAGAAAA
CGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGCGGAACTCTGAACGGGCGCGG
GAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCTTGACTGTTGGGGCAAAAGGT
GCCAGGGCCCCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTTGTATGGAGTTAGAAGCGTCTGT
ATCTCTGGAGCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAGAGAGATCCTGATACCTCTGTGGGGACTGTGGGGACTTTTGGGACCCCA
CACACTCCAGGTGGGATCAGATGCTGCTCCAACCATGCAGTTCCTGGTGAGGGTCAGAAGGGGACGGTACCAAGAGTAGCGCTTAGCCCT
TACCCAGGAAATATCCTTCATGGCCACAGAAATGGAGGGCGCCCAGGATCCAGGCAGCCACCGGGAACAGTCAGCTTTCTTTATTAAATG

>53566_53566_2_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000398761_ARHGAP22_chr10_49654662_ENST00000417247_length(amino acids)=406AA_BP=
MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK
KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD
GKNKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPT
TGNTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKE

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>53566_53566_3_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000249601_length(transcript)=1475nt_BP=889nt
AAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAAAACCATGAAAAGAATAT
ATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATA
TTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCAATAAGTAATACCATATTGAA
GCAACAGAACGTTAATATTACTAAGCTAAGAAGATGGTGTCTCTGAAAGCAAAGCTAAATCATTTAAGGCAAAGCATGTTGAAACAAAAA
GCTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAG
AGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCC
CTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTT
CTGAAGCTTGAGTTTGAACGCCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTG
CAGTCCAAGAAGCTGACCGCCATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTC
TTTACTTTCCTAAAGAACATTAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAG
GGAGTGCTGACCTGAGAAAACGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGC
GGAACTCTGAACGGGCGCGGGAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCT
TGACTGTTGGGGCAAAAGGTGCCAGGGCCCCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTTGT
ATGGAGTTAGAAGCGTCTGTATCTCTGGAGCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAGAGAGATCCTGATACCTCTGTGGGGACTG
TGGGGACTTTTGGGACCCCACACACTCCAGGTGGGATCAGATGCTGCTCCAACCATGCAGTTCCTGGTGAGGGTCAGAAGGGGACGGTAC
CAAGAGTAGCGCTTAGCCCTTACCCAGGAAATATCCTTCATGGCCACAGAAATGGAGGGCGCCCAGGATCCAGGCAGCCACCGGGAACAG

>53566_53566_3_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000249601_length(amino acids)=203AA_BP=
MVSLKAKLNHLRQSMLKQKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLK
GKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVD

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>53566_53566_4_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000417912_length(transcript)=1169nt_BP=889nt
AAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAAAACCATGAAAAGAATAT
ATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATA
TTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCAATAAGTAATACCATATTGAA
GCAACAGAACGTTAATATTACTAAGCTAAGAAGATGGTGTCTCTGAAAGCAAAGCTAAATCATTTAAGGCAAAGCATGTTGAAACAAAAA
GCTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAG
AGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCC
CTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTT
CTGAAGCTTGAGTTTGAACGCCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTG
CAGTCCAAGAAGCTGACCGCCATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTC
TTTACTTTCCTAAAGAACATTAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAG
GGAGTGCTGACCTGAGAAAACGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGC
GGAACTCTGAACGGGCGCGGGAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCT

>53566_53566_4_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000417912_length(amino acids)=203AA_BP=
MVSLKAKLNHLRQSMLKQKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLK
GKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVD

--------------------------------------------------------------
>53566_53566_5_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000435790_length(transcript)=1267nt_BP=889nt
AAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAAAACCATGAAAAGAATAT
ATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATA
TTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCAATAAGTAATACCATATTGAA
GCAACAGAACGTTAATATTACTAAGCTAAGAAGATGGTGTCTCTGAAAGCAAAGCTAAATCATTTAAGGCAAAGCATGTTGAAACAAAAA
GCTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAG
AGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCC
CTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTT
CTGAAGCTTGAGTTTGAACGCCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTG
CAGTCCAAGAAGCTGACCGCCATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTC
TTTACTTTCCTAAAGAACATTAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAG
GGAGTGCTGACCTGAGAAAACGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGC
GGAACTCTGAACGGGCGCGGGAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCT
TGACTGTTGGGGCAAAAGGTGCCAGGGCCCCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTTGT
ATGGAGTTAGAAGCGTCTGTATCTCTGGAGCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAGAGAGATCCTGATACCTCTGTGGGGACTG

>53566_53566_5_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000435790_length(amino acids)=203AA_BP=
MVSLKAKLNHLRQSMLKQKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLK
GKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVD

--------------------------------------------------------------
>53566_53566_6_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000401998_ARHGAP22_chr10_49654662_ENST00000417247_length(transcript)=1834nt_BP=1251nt
GTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCAC
TTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGG
CTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAA
AAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAG
AAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAA
TCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAA
CACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAAAATTTCCCAGGAACGAGAAA
AATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTT
CCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAA
TTAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAG
CCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATG
TTCTGAAGCTTGAGTTTGAACGCCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGG
TGCAGTCCAAGAAGCTGACCGCCATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACT
TCTTTACTTTCCTAAAGAACATTAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGA
AGGGAGTGCTGACCTGAGAAAACGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCT
GCGGAACTCTGAACGGGCGCGGGAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAG
CTTGACTGTTGGGGCAAAAGGTGCCAGGGCCCCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTT
GTATGGAGTTAGAAGCGTCTGTATCTCTGGAGCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAGAGAGATCCTGATACCTCTGTGGGGAC
TGTGGGGACTTTTGGGACCCCACACACTCCAGGTGGGATCAGATGCTGCTCCAACCATGCAGTTCCTGGTGAGGGTCAGAAGGGGACGGT
ACCAAGAGTAGCGCTTAGCCCTTACCCAGGAAATATCCTTCATGGCCACAGAAATGGAGGGCGCCCAGGATCCAGGCAGCCACCGGGAAC

>53566_53566_6_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000401998_ARHGAP22_chr10_49654662_ENST00000417247_length(amino acids)=404AA_BP=
MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK
KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD
GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPTTG
NTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGK

--------------------------------------------------------------
>53566_53566_7_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000249601_length(transcript)=1266nt_BP=680nt
CAAATGGGACACCTAGAAAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAA
AACCATGAAAAGAATATATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGCTCCTCAGAGAAATTTTGAAATTGCCTT
CAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGG
TATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCT
GAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGTTTGAACGCCATGACCC
TGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTGCAGTCCAAGAAGCTGACCGCCATGCAGAG
GCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTCTTTACTTTCCTAAAGAACATTAATGATGT
GGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAGGGAGTGCTGACCTGAGAAAACGAATGTCC
CGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGCGGAACTCTGAACGGGCGCGGGAGGATGCG
GAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCTTGACTGTTGGGGCAAAAGGTGCCAGGGCC
CCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTTGTATGGAGTTAGAAGCGTCTGTATCTCTGGA
GCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAGAGAGATCCTGATACCTCTGTGGGGACTGTGGGGACTTTTGGGACCCCACACACTCCA
GGTGGGATCAGATGCTGCTCCAACCATGCAGTTCCTGGTGAGGGTCAGAAGGGGACGGTACCAAGAGTAGCGCTTAGCCCTTACCCAGGA
AATATCCTTCATGGCCACAGAAATGGAGGGCGCCCAGGATCCAGGCAGCCACCGGGAACAGTCAGCTTTCTTTATTAAATGTGCTCACAA

>53566_53566_7_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000249601_length(amino acids)=207AA_BP=
MEKTMKRIYTYRRAKEIFKDTPKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFG
ADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNI

--------------------------------------------------------------
>53566_53566_8_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000417912_length(transcript)=960nt_BP=680nt
CAAATGGGACACCTAGAAAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAA
AACCATGAAAAGAATATATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGCTCCTCAGAGAAATTTTGAAATTGCCTT
CAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGG
TATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCT
GAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGTTTGAACGCCATGACCC
TGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTGCAGTCCAAGAAGCTGACCGCCATGCAGAG
GCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTCTTTACTTTCCTAAAGAACATTAATGATGT
GGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAGGGAGTGCTGACCTGAGAAAACGAATGTCC
CGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGCGGAACTCTGAACGGGCGCGGGAGGATGCG
GAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCTTGACTGTTGGGGCAAAAGGTGCCAGGGCC

>53566_53566_8_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000417912_length(amino acids)=207AA_BP=
MEKTMKRIYTYRRAKEIFKDTPKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFG
ADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNI

--------------------------------------------------------------
>53566_53566_9_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000435790_length(transcript)=1058nt_BP=680nt
CAAATGGGACACCTAGAAAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAA
AACCATGAAAAGAATATATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGCTCCTCAGAGAAATTTTGAAATTGCCTT
CAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGG
TATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCT
GAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGTTTGAACGCCATGACCC
TGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTGCAGTCCAAGAAGCTGACCGCCATGCAGAG
GCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTCTTTACTTTCCTAAAGAACATTAATGATGT
GGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAGGGAGTGCTGACCTGAGAAAACGAATGTCC
CGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGCGGAACTCTGAACGGGCGCGGGAGGATGCG
GAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCTTGACTGTTGGGGCAAAAGGTGCCAGGGCC
CCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTTGTATGGAGTTAGAAGCGTCTGTATCTCTGGA

>53566_53566_9_MICU1-ARHGAP22_MICU1_chr10_74167686_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000435790_length(amino acids)=207AA_BP=
MEKTMKRIYTYRRAKEIFKDTPKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFG
ADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNI

--------------------------------------------------------------
>53566_53566_10_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000361114_ARHGAP22_chr10_49654662_ENST00000417247_length(transcript)=1860nt_BP=1277nt
GGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTT
GGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCA
GATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGA
ATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAA
GACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGAT
TCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGAC
ACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGG
AAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGA
CTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGT
AGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAA
CACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGA
ATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGTTTGAACGCCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGG
TGGCATGCTACTTGCCTACAGTGGGGTGCAGTCCAAGAAGCTGACCGCCATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGG
TCTGACATTTCAGGAGGTGGAGAACTTCTTTACTTTCCTAAAGAACATTAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGG
AGCATCTCTTGATAAAGAATCGAAGAAGGGAGTGCTGACCTGAGAAAACGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAA
AAATACATCATGCTGGAAATAAAGCTGCGGAACTCTGAACGGGCGCGGGAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATG
GAGGAGTTTTTTTCGACCCTAGGAAGCTTGACTGTTGGGGCAAAAGGTGCCAGGGCCCCAAAGTAAAAGGAATGGCAGAGCTCACTTCTG
TACCACGTCTGCTGGTCTCCAGCCTTGTATGGAGTTAGAAGCGTCTGTATCTCTGGAGCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAG
AGAGATCCTGATACCTCTGTGGGGACTGTGGGGACTTTTGGGACCCCACACACTCCAGGTGGGATCAGATGCTGCTCCAACCATGCAGTT
CCTGGTGAGGGTCAGAAGGGGACGGTACCAAGAGTAGCGCTTAGCCCTTACCCAGGAAATATCCTTCATGGCCACAGAAATGGAGGGCGC

>53566_53566_10_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000361114_ARHGAP22_chr10_49654662_ENST00000417247_length(amino acids)=404AA_BP=
MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK
KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD
GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTG
NTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGK

--------------------------------------------------------------
>53566_53566_11_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000398761_ARHGAP22_chr10_49654662_ENST00000417247_length(transcript)=1902nt_BP=1319nt
AGGCCCAGCGGCTAGGAGAGTCACGTGAGAGTGGGCGGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGG
GCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGG
TTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGC
AAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAA
TAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATT
CAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGT
CATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTT
GGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAATAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTAT
ATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGA
AATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAATTAGCATCATTCGCTCCCAAAC
CAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGG
AGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGTTTGAACG
CCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTGCAGTCCAAGAAGCTGACCGC
CATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTCTTTACTTTCCTAAAGAACAT
TAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAGGGAGTGCTGACCTGAGAAAA
CGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGCGGAACTCTGAACGGGCGCGG
GAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCTTGACTGTTGGGGCAAAAGGT
GCCAGGGCCCCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTTGTATGGAGTTAGAAGCGTCTGT
ATCTCTGGAGCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAGAGAGATCCTGATACCTCTGTGGGGACTGTGGGGACTTTTGGGACCCCA
CACACTCCAGGTGGGATCAGATGCTGCTCCAACCATGCAGTTCCTGGTGAGGGTCAGAAGGGGACGGTACCAAGAGTAGCGCTTAGCCCT
TACCCAGGAAATATCCTTCATGGCCACAGAAATGGAGGGCGCCCAGGATCCAGGCAGCCACCGGGAACAGTCAGCTTTCTTTATTAAATG

>53566_53566_11_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000398761_ARHGAP22_chr10_49654662_ENST00000417247_length(amino acids)=406AA_BP=
MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK
KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD
GKNKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPT
TGNTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKE

--------------------------------------------------------------
>53566_53566_12_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000249601_length(transcript)=1475nt_BP=889nt
AAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAAAACCATGAAAAGAATAT
ATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATA
TTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCAATAAGTAATACCATATTGAA
GCAACAGAACGTTAATATTACTAAGCTAAGAAGATGGTGTCTCTGAAAGCAAAGCTAAATCATTTAAGGCAAAGCATGTTGAAACAAAAA
GCTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAG
AGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCC
CTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTT
CTGAAGCTTGAGTTTGAACGCCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTG
CAGTCCAAGAAGCTGACCGCCATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTC
TTTACTTTCCTAAAGAACATTAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAG
GGAGTGCTGACCTGAGAAAACGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGC
GGAACTCTGAACGGGCGCGGGAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCT
TGACTGTTGGGGCAAAAGGTGCCAGGGCCCCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTTGT
ATGGAGTTAGAAGCGTCTGTATCTCTGGAGCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAGAGAGATCCTGATACCTCTGTGGGGACTG
TGGGGACTTTTGGGACCCCACACACTCCAGGTGGGATCAGATGCTGCTCCAACCATGCAGTTCCTGGTGAGGGTCAGAAGGGGACGGTAC
CAAGAGTAGCGCTTAGCCCTTACCCAGGAAATATCCTTCATGGCCACAGAAATGGAGGGCGCCCAGGATCCAGGCAGCCACCGGGAACAG

>53566_53566_12_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000249601_length(amino acids)=203AA_BP=
MVSLKAKLNHLRQSMLKQKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLK
GKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVD

--------------------------------------------------------------
>53566_53566_13_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000417912_length(transcript)=1169nt_BP=889nt
AAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAAAACCATGAAAAGAATAT
ATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATA
TTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCAATAAGTAATACCATATTGAA
GCAACAGAACGTTAATATTACTAAGCTAAGAAGATGGTGTCTCTGAAAGCAAAGCTAAATCATTTAAGGCAAAGCATGTTGAAACAAAAA
GCTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAG
AGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCC
CTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTT
CTGAAGCTTGAGTTTGAACGCCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTG
CAGTCCAAGAAGCTGACCGCCATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTC
TTTACTTTCCTAAAGAACATTAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAG
GGAGTGCTGACCTGAGAAAACGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGC
GGAACTCTGAACGGGCGCGGGAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCT

>53566_53566_13_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000417912_length(amino acids)=203AA_BP=
MVSLKAKLNHLRQSMLKQKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLK
GKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVD

--------------------------------------------------------------
>53566_53566_14_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000435790_length(transcript)=1267nt_BP=889nt
AAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAAAACCATGAAAAGAATAT
ATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATA
TTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCAATAAGTAATACCATATTGAA
GCAACAGAACGTTAATATTACTAAGCTAAGAAGATGGTGTCTCTGAAAGCAAAGCTAAATCATTTAAGGCAAAGCATGTTGAAACAAAAA
GCTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAG
AGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCC
CTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTT
CTGAAGCTTGAGTTTGAACGCCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTG
CAGTCCAAGAAGCTGACCGCCATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTC
TTTACTTTCCTAAAGAACATTAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAG
GGAGTGCTGACCTGAGAAAACGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGC
GGAACTCTGAACGGGCGCGGGAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCT
TGACTGTTGGGGCAAAAGGTGCCAGGGCCCCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTTGT
ATGGAGTTAGAAGCGTCTGTATCTCTGGAGCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAGAGAGATCCTGATACCTCTGTGGGGACTG

>53566_53566_14_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000398763_ARHGAP22_chr10_49654662_ENST00000435790_length(amino acids)=203AA_BP=
MVSLKAKLNHLRQSMLKQKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLK
GKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVD

--------------------------------------------------------------
>53566_53566_15_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000401998_ARHGAP22_chr10_49654662_ENST00000417247_length(transcript)=1834nt_BP=1251nt
GTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCAC
TTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGG
CTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAA
AAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAG
AAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAA
TCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAA
CACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAAAATTTCCCAGGAACGAGAAA
AATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTT
CCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAA
TTAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAG
CCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATG
TTCTGAAGCTTGAGTTTGAACGCCATGACCCTGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGG
TGCAGTCCAAGAAGCTGACCGCCATGCAGAGGCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACT
TCTTTACTTTCCTAAAGAACATTAATGATGTGGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGA
AGGGAGTGCTGACCTGAGAAAACGAATGTCCCGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCT
GCGGAACTCTGAACGGGCGCGGGAGGATGCGGAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAG
CTTGACTGTTGGGGCAAAAGGTGCCAGGGCCCCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTT
GTATGGAGTTAGAAGCGTCTGTATCTCTGGAGCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAGAGAGATCCTGATACCTCTGTGGGGAC
TGTGGGGACTTTTGGGACCCCACACACTCCAGGTGGGATCAGATGCTGCTCCAACCATGCAGTTCCTGGTGAGGGTCAGAAGGGGACGGT
ACCAAGAGTAGCGCTTAGCCCTTACCCAGGAAATATCCTTCATGGCCACAGAAATGGAGGGCGCCCAGGATCCAGGCAGCCACCGGGAAC

>53566_53566_15_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000401998_ARHGAP22_chr10_49654662_ENST00000417247_length(amino acids)=404AA_BP=
MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK
KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD
GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPTTG
NTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGK

--------------------------------------------------------------
>53566_53566_16_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000249601_length(transcript)=1266nt_BP=680nt
CAAATGGGACACCTAGAAAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAA
AACCATGAAAAGAATATATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGCTCCTCAGAGAAATTTTGAAATTGCCTT
CAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGG
TATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCT
GAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGTTTGAACGCCATGACCC
TGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTGCAGTCCAAGAAGCTGACCGCCATGCAGAG
GCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTCTTTACTTTCCTAAAGAACATTAATGATGT
GGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAGGGAGTGCTGACCTGAGAAAACGAATGTCC
CGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGCGGAACTCTGAACGGGCGCGGGAGGATGCG
GAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCTTGACTGTTGGGGCAAAAGGTGCCAGGGCC
CCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTTGTATGGAGTTAGAAGCGTCTGTATCTCTGGA
GCAGCCAGGCGCTCTGGAGCCAGCTGGAGAGAGAGAGATCCTGATACCTCTGTGGGGACTGTGGGGACTTTTGGGACCCCACACACTCCA
GGTGGGATCAGATGCTGCTCCAACCATGCAGTTCCTGGTGAGGGTCAGAAGGGGACGGTACCAAGAGTAGCGCTTAGCCCTTACCCAGGA
AATATCCTTCATGGCCACAGAAATGGAGGGCGCCCAGGATCCAGGCAGCCACCGGGAACAGTCAGCTTTCTTTATTAAATGTGCTCACAA

>53566_53566_16_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000249601_length(amino acids)=207AA_BP=
MEKTMKRIYTYRRAKEIFKDTPKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFG
ADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNI

--------------------------------------------------------------
>53566_53566_17_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000417912_length(transcript)=960nt_BP=680nt
CAAATGGGACACCTAGAAAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAA
AACCATGAAAAGAATATATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGCTCCTCAGAGAAATTTTGAAATTGCCTT
CAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGG
TATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCT
GAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGTTTGAACGCCATGACCC
TGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTGCAGTCCAAGAAGCTGACCGCCATGCAGAG
GCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTCTTTACTTTCCTAAAGAACATTAATGATGT
GGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAGGGAGTGCTGACCTGAGAAAACGAATGTCC
CGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGCGGAACTCTGAACGGGCGCGGGAGGATGCG
GAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCTTGACTGTTGGGGCAAAAGGTGCCAGGGCC

>53566_53566_17_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000417912_length(amino acids)=207AA_BP=
MEKTMKRIYTYRRAKEIFKDTPKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFG
ADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNI

--------------------------------------------------------------
>53566_53566_18_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000435790_length(transcript)=1058nt_BP=680nt
CAAATGGGACACCTAGAAAGACTTTATTATTTTGCTTTTCTGAGCTAATCAATGACTTTAATTTGGAAAAGCAACTAAATATTTGGAGAA
AACCATGAAAAGAATATATACTTACAGACGGGCCAAGGAGATCTTCAAGGACACTCCTAAAGCTCCTCAGAGAAATTTTGAAATTGCCTT
CAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGG
TATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCT
GAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGTTTGAACGCCATGACCC
TGTGGATGGGAGAATTACTGAGAGGCAGTTTGGTGGCATGCTACTTGCCTACAGTGGGGTGCAGTCCAAGAAGCTGACCGCCATGCAGAG
GCAGCTCAAGAAGCACTTCAAAGAAGGAAAGGGTCTGACATTTCAGGAGGTGGAGAACTTCTTTACTTTCCTAAAGAACATTAATGATGT
GGACACTGCATTGAGTTTTTACCATATGGCTGGAGCATCTCTTGATAAAGAATCGAAGAAGGGAGTGCTGACCTGAGAAAACGAATGTCC
CGGTTAGAAGAAGAACTGGACCAGGAAAAGAAAAAATACATCATGCTGGAAATAAAGCTGCGGAACTCTGAACGGGCGCGGGAGGATGCG
GAGAGGAGGAACCAGCTGTTGCAGAGGGAAATGGAGGAGTTTTTTTCGACCCTAGGAAGCTTGACTGTTGGGGCAAAAGGTGCCAGGGCC
CCAAAGTAAAAGGAATGGCAGAGCTCACTTCTGTACCACGTCTGCTGGTCTCCAGCCTTGTATGGAGTTAGAAGCGTCTGTATCTCTGGA

>53566_53566_18_MICU1-ARHGAP22_MICU1_chr10_74167687_ENST00000418483_ARHGAP22_chr10_49654662_ENST00000435790_length(amino acids)=207AA_BP=
MEKTMKRIYTYRRAKEIFKDTPKAPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFG
ADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MICU1-ARHGAP22


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MICU1-ARHGAP22


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MICU1-ARHGAP22


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource