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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:MICU1-DNAJB12 (FusionGDB2 ID:53569) |
Fusion Gene Summary for MICU1-DNAJB12 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MICU1-DNAJB12 | Fusion gene ID: 53569 | Hgene | Tgene | Gene symbol | MICU1 | DNAJB12 | Gene ID | 10367 | 54788 |
| Gene name | mitochondrial calcium uptake 1 | DnaJ heat shock protein family (Hsp40) member B12 | |
| Synonyms | CALC|CBARA1|EFHA3|MPXPS|ara CALC | DJ10 | |
| Cytomap | 10q22.1 | 10q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | calcium uptake protein 1, mitochondrialatopy-related autoantigen CALCcalcium-binding atopy-related autoantigen 1 | dnaJ homolog subfamily B member 12DnaJ (Hsp40) homolog, subfamily B, member 12 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q9BPX6 | Q9NXW2 | |
| Ensembl transtripts involved in fusion gene | ENST00000361114, ENST00000398761, ENST00000401998, ENST00000604025, ENST00000398763, ENST00000418483, | ENST00000338820, ENST00000394903, ENST00000444643, ENST00000461919, | |
| Fusion gene scores | * DoF score | 13 X 11 X 8=1144 | 7 X 5 X 6=210 |
| # samples | 17 | 8 | |
| ** MAII score | log2(17/1144*10)=-2.75048040064069 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/210*10)=-1.39231742277876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MICU1 [Title/Abstract] AND DNAJB12 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | MICU1(74385768)-DNAJB12(74104885), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | MICU1-DNAJB12 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MICU1 | GO:0006851 | mitochondrial calcium ion transmembrane transport | 24560927 |
| Hgene | MICU1 | GO:0051260 | protein homooligomerization | 24514027 |
| Hgene | MICU1 | GO:0051561 | positive regulation of mitochondrial calcium ion concentration | 24560927 |
| Hgene | MICU1 | GO:0070509 | calcium ion import | 20693986 |
| Tgene | DNAJB12 | GO:0034622 | cellular protein-containing complex assembly | 27916661 |
| Tgene | DNAJB12 | GO:0036503 | ERAD pathway | 21148293|21150129 |
| Tgene | DNAJB12 | GO:0051085 | chaperone cofactor-dependent protein refolding | 27916661 |
| Tgene | DNAJB12 | GO:0071218 | cellular response to misfolded protein | 21148293|21150129 |
| Fusion gene breakpoints across MICU1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across DNAJB12 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | HNSC | TCGA-CQ-A4CG-01A | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| ChimerDB4 | STAD | TCGA-CG-4441-01A | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
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Fusion Gene ORF analysis for MICU1-DNAJB12 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000361114 | ENST00000338820 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-3CDS | ENST00000361114 | ENST00000394903 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-3CDS | ENST00000361114 | ENST00000444643 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-3CDS | ENST00000398761 | ENST00000338820 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-3CDS | ENST00000398761 | ENST00000394903 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-3CDS | ENST00000398761 | ENST00000444643 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-3CDS | ENST00000401998 | ENST00000338820 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-3CDS | ENST00000401998 | ENST00000394903 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-3CDS | ENST00000401998 | ENST00000444643 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-3CDS | ENST00000604025 | ENST00000338820 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-3CDS | ENST00000604025 | ENST00000394903 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-3CDS | ENST00000604025 | ENST00000444643 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-intron | ENST00000361114 | ENST00000461919 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-intron | ENST00000398761 | ENST00000461919 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-intron | ENST00000401998 | ENST00000461919 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| 5UTR-intron | ENST00000604025 | ENST00000461919 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| Frame-shift | ENST00000398763 | ENST00000338820 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| Frame-shift | ENST00000398763 | ENST00000394903 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| Frame-shift | ENST00000398763 | ENST00000444643 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| Frame-shift | ENST00000398763 | ENST00000461919 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| Frame-shift | ENST00000418483 | ENST00000338820 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| Frame-shift | ENST00000418483 | ENST00000394903 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| Frame-shift | ENST00000418483 | ENST00000444643 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| Frame-shift | ENST00000418483 | ENST00000461919 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000361114 | ENST00000338820 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000361114 | ENST00000394903 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000361114 | ENST00000444643 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000361114 | ENST00000461919 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000398761 | ENST00000338820 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000398761 | ENST00000394903 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000398761 | ENST00000444643 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000398761 | ENST00000461919 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000401998 | ENST00000338820 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000401998 | ENST00000394903 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000401998 | ENST00000444643 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| In-frame | ENST00000401998 | ENST00000461919 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| intron-3CDS | ENST00000398763 | ENST00000338820 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| intron-3CDS | ENST00000398763 | ENST00000394903 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| intron-3CDS | ENST00000398763 | ENST00000444643 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| intron-3CDS | ENST00000418483 | ENST00000338820 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| intron-3CDS | ENST00000418483 | ENST00000394903 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| intron-3CDS | ENST00000418483 | ENST00000444643 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| intron-3CDS | ENST00000604025 | ENST00000338820 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| intron-3CDS | ENST00000604025 | ENST00000394903 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| intron-3CDS | ENST00000604025 | ENST00000444643 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| intron-3CDS | ENST00000604025 | ENST00000461919 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - |
| intron-intron | ENST00000398763 | ENST00000461919 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| intron-intron | ENST00000418483 | ENST00000461919 | MICU1 | chr10 | 74385768 | - | DNAJB12 | chr10 | 74104885 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000401998 | MICU1 | chr10 | 74234858 | - | ENST00000394903 | DNAJB12 | chr10 | 74096454 | - | 3117 | 1004 | 62 | 1036 | 324 |
| ENST00000401998 | MICU1 | chr10 | 74234858 | - | ENST00000338820 | DNAJB12 | chr10 | 74096454 | - | 4279 | 1004 | 62 | 1036 | 324 |
| ENST00000401998 | MICU1 | chr10 | 74234858 | - | ENST00000444643 | DNAJB12 | chr10 | 74096454 | - | 3116 | 1004 | 62 | 1036 | 324 |
| ENST00000401998 | MICU1 | chr10 | 74234858 | - | ENST00000461919 | DNAJB12 | chr10 | 74096454 | - | 1812 | 1004 | 62 | 1036 | 324 |
| ENST00000361114 | MICU1 | chr10 | 74234858 | - | ENST00000394903 | DNAJB12 | chr10 | 74096454 | - | 3143 | 1030 | 88 | 1062 | 324 |
| ENST00000361114 | MICU1 | chr10 | 74234858 | - | ENST00000338820 | DNAJB12 | chr10 | 74096454 | - | 4305 | 1030 | 88 | 1062 | 324 |
| ENST00000361114 | MICU1 | chr10 | 74234858 | - | ENST00000444643 | DNAJB12 | chr10 | 74096454 | - | 3142 | 1030 | 88 | 1062 | 324 |
| ENST00000361114 | MICU1 | chr10 | 74234858 | - | ENST00000461919 | DNAJB12 | chr10 | 74096454 | - | 1838 | 1030 | 88 | 1062 | 324 |
| ENST00000398761 | MICU1 | chr10 | 74234858 | - | ENST00000394903 | DNAJB12 | chr10 | 74096454 | - | 3185 | 1072 | 124 | 1104 | 326 |
| ENST00000398761 | MICU1 | chr10 | 74234858 | - | ENST00000338820 | DNAJB12 | chr10 | 74096454 | - | 4347 | 1072 | 124 | 1104 | 326 |
| ENST00000398761 | MICU1 | chr10 | 74234858 | - | ENST00000444643 | DNAJB12 | chr10 | 74096454 | - | 3184 | 1072 | 124 | 1104 | 326 |
| ENST00000398761 | MICU1 | chr10 | 74234858 | - | ENST00000461919 | DNAJB12 | chr10 | 74096454 | - | 1880 | 1072 | 124 | 1104 | 326 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000401998 | ENST00000394903 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.000608716 | 0.9993913 |
| ENST00000401998 | ENST00000338820 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.001278138 | 0.9987218 |
| ENST00000401998 | ENST00000444643 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.000597883 | 0.99940217 |
| ENST00000401998 | ENST00000461919 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.000856444 | 0.9991435 |
| ENST00000361114 | ENST00000394903 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.000580118 | 0.9994199 |
| ENST00000361114 | ENST00000338820 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.001218831 | 0.99878114 |
| ENST00000361114 | ENST00000444643 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.000568571 | 0.99943143 |
| ENST00000361114 | ENST00000461919 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.000773798 | 0.9992262 |
| ENST00000398761 | ENST00000394903 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.000585748 | 0.9994143 |
| ENST00000398761 | ENST00000338820 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.001242626 | 0.99875736 |
| ENST00000398761 | ENST00000444643 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.000578464 | 0.9994216 |
| ENST00000398761 | ENST00000461919 | MICU1 | chr10 | 74234858 | - | DNAJB12 | chr10 | 74096454 | - | 0.00077875 | 0.9992212 |
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Fusion Genomic Features for MICU1-DNAJB12 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for MICU1-DNAJB12 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:74385768/chr10:74104885) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MICU1 | DNAJB12 |
| FUNCTION: Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains (PubMed:20693986, PubMed:23101630, PubMed:23747253, PubMed:24313810, PubMed:24332854, PubMed:24503055, PubMed:24560927, PubMed:26341627, PubMed:26903221, PubMed:27099988). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulates and inhibits MCU activity, depending on the concentration of calcium. MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptake (PubMed:26903221). Acts as a gatekeeper of MCU at low concentration of calcium, preventing channel opening (PubMed:26903221). Enhances MCU opening at high calcium concentration, allowing a rapid response of mitochondria to calcium signals generated in the cytoplasm (PubMed:24560927, PubMed:26903221). Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake (PubMed:22904319). Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG (PubMed:16002733). {ECO:0000269|PubMed:16002733, ECO:0000269|PubMed:20693986, ECO:0000269|PubMed:22904319, ECO:0000269|PubMed:23101630, ECO:0000269|PubMed:23747253, ECO:0000269|PubMed:24313810, ECO:0000269|PubMed:24332854, ECO:0000269|PubMed:24503055, ECO:0000269|PubMed:24560927, ECO:0000269|PubMed:26341627, ECO:0000269|PubMed:26903221, ECO:0000269|PubMed:27099988}. | FUNCTION: Acts as a co-chaperone with HSPA8/Hsc70; required to promote protein folding and trafficking, prevent aggregation of client proteins, and promote unfolded proteins to endoplasmic reticulum-associated degradation (ERAD) pathway (PubMed:21150129, PubMed:21148293). Acts by determining HSPA8/Hsc70's ATPase and polypeptide-binding activities. Can also act independently of HSPA8/Hsc70: together with DNAJB14, acts as a chaperone that promotes maturation of potassium channels KCND2 and KCNH2 by stabilizing nascent channel subunits and assembling them into tetramers (PubMed:27916661). While stabilization of nascent channel proteins is dependent on HSPA8/Hsc70, the process of oligomerization of channel subunits is independent of HSPA8/Hsc70 (PubMed:27916661). When overexpressed, forms membranous structures together with DNAJB14 and HSPA8/Hsc70 within the nucleus; the role of these structures, named DJANGOs, is still unclear (PubMed:24732912). {ECO:0000269|PubMed:21148293, ECO:0000269|PubMed:21150129, ECO:0000269|PubMed:24732912, ECO:0000269|PubMed:27916661}.; FUNCTION: (Microbial infection) In case of infection by polyomavirus, involved in the virus endoplasmic reticulum membrane penetration and infection (PubMed:21673190, PubMed:24675744). {ECO:0000269|PubMed:21673190, ECO:0000269|PubMed:24675744}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000361114 | - | 8 | 12 | 231_242 | 311 | 477.0 | Calcium binding | 1 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000361114 | - | 8 | 12 | 218_253 | 311 | 477.0 | Domain | EF-hand 1 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000361114 | - | 8 | 12 | 99_110 | 311 | 477.0 | Region | Polybasic region |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000398763 | - | 5 | 9 | 99_110 | 113 | 279.0 | Region | Polybasic region |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000418483 | - | 3 | 7 | 99_110 | 113 | 279.0 | Region | Polybasic region |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000361114 | - | 8 | 12 | 34_52 | 311 | 477.0 | Transmembrane | Helical |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000398763 | - | 5 | 9 | 34_52 | 113 | 279.0 | Transmembrane | Helical |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000418483 | - | 3 | 7 | 34_52 | 113 | 279.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000361114 | - | 8 | 12 | 421_432 | 311 | 477.0 | Calcium binding | 2 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000398763 | - | 5 | 9 | 231_242 | 113 | 279.0 | Calcium binding | 1 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000398763 | - | 5 | 9 | 421_432 | 113 | 279.0 | Calcium binding | 2 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000418483 | - | 3 | 7 | 231_242 | 113 | 279.0 | Calcium binding | 1 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000418483 | - | 3 | 7 | 421_432 | 113 | 279.0 | Calcium binding | 2 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000361114 | - | 8 | 12 | 408_443 | 311 | 477.0 | Domain | EF-hand 2 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000398763 | - | 5 | 9 | 218_253 | 113 | 279.0 | Domain | EF-hand 1 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000398763 | - | 5 | 9 | 408_443 | 113 | 279.0 | Domain | EF-hand 2 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000418483 | - | 3 | 7 | 218_253 | 113 | 279.0 | Domain | EF-hand 1 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000418483 | - | 3 | 7 | 408_443 | 113 | 279.0 | Domain | EF-hand 2 |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000361114 | - | 8 | 12 | 455_465 | 311 | 477.0 | Region | C-helix region |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000398763 | - | 5 | 9 | 455_465 | 113 | 279.0 | Region | C-helix region |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000418483 | - | 3 | 7 | 455_465 | 113 | 279.0 | Region | C-helix region |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000361114 | - | 8 | 12 | 53_476 | 311 | 477.0 | Topological domain | Mitochondrial intermembrane |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000398763 | - | 5 | 9 | 53_476 | 113 | 279.0 | Topological domain | Mitochondrial intermembrane |
| Hgene | MICU1 | chr10:74234858 | chr10:74096454 | ENST00000418483 | - | 3 | 7 | 53_476 | 113 | 279.0 | Topological domain | Mitochondrial intermembrane |
| Tgene | DNAJB12 | chr10:74234858 | chr10:74096454 | ENST00000444643 | 5 | 9 | 112_176 | 277 | 807.6666666666666 | Domain | J | |
| Tgene | DNAJB12 | chr10:74234858 | chr10:74096454 | ENST00000444643 | 5 | 9 | 1_243 | 277 | 807.6666666666666 | Topological domain | Cytoplasmic | |
| Tgene | DNAJB12 | chr10:74234858 | chr10:74096454 | ENST00000444643 | 5 | 9 | 265_375 | 277 | 807.6666666666666 | Topological domain | Lumenal | |
| Tgene | DNAJB12 | chr10:74234858 | chr10:74096454 | ENST00000444643 | 5 | 9 | 244_264 | 277 | 807.6666666666666 | Transmembrane | Helical |
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Fusion Gene Sequence for MICU1-DNAJB12 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >53569_53569_1_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000361114_DNAJB12_chr10_74096454_ENST00000338820_length(transcript)=4305nt_BP=1030nt GGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTT GGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCA GATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGA ATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAA GACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGAT TCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGAC ACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGG AAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGA CTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGT AGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAA CACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGA ATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGGTCCGTGGGCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCT ACTATGTGGGAGACACTTTCTCCGAAGAGTACACAGGCTCCAGCCTCAAAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACC TCCGGAACAACTGCTGGAAGGAGAAGCAGCAGAAGGAAGGCTTGCTGTACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAG CACAGAAGATGGGCACCCCCAGCTGCAGCCGACTGTCAGAGGTGCAGGCCTCCCTGCATGGATAGTCCTGGGCCAGCCACACCACCGAGG TCCAAGTATGAGCCAGGGCTGCCTCCACCCTGCAACTCCTGGCAGCTTTGGCCCTGGTCATGAGCAGAGGAGGGAGGGGGAGAAAGGGAG GAAGCCTGGTGATTGTGGCAAAGACTCCTGTCCCCAGCCTGACCTCCAGCCTCCAGAGACCGAGCAGCTGTGGGGCCTGCTGGGAAACCA AGGTCGGTTTCCGCCCTCTAGCGATGCTGTCCTCCCCACTCCTCCGCTCTGCTCCCTGGCTCCAGGGGTGTGGGGGACCCCAGAACCAGG CAGAGTGGGAACTTGAAACTGTTGCTGAGGGCCACCCGGGGCTTCTTGGTCCACTCCAGCCATCAGTCAGCACGGCCCTTTCTCCAGCAC AGCAGACTATTGTCCGTGCCCTGGTATTTAGGCCATCACATATGGTGGGGCCCAAGAGAGCCCCATATGCACACTGCCTGCCTGATACCA GGAAGAACCATGTGGGAATAGGTGGGCCAAGAGCCCTCCCCTTTCTCCATCCCTCCAGCTAGGAGGAAATGGAGCAAGATGAACAGGCAG CCACGAGGTGGGTGGGAGCTGGCAGTCTTGGTGGCGGCAGGGGCCGCGGGCCCTGACCACCCCCCTCTGGTGGGATCTGAGGCACTCTCT CGAATGCCGTCACACCTGGCAGCCTGGAAGCCACAGGCATCCGGCCTTGCCCAGGCATCTCGCCTGCGGTCTGAGGAAGGGAACAGAAGG TCATGAGTTCAGGGTCAGACGCAGCCGCTCAGCACAGGAGGGGTGGAGGGGAAATGAGAGTTGCTGGTAGCAGGCTCCCTCCTTCTGCAG CCCGGCGAATGGGGGCGCTGGGCTCTGTTCCCAGCGTTTGCCAGAGGTGGCCACTTCAGCCAAGCCCAGAGAAGTGTGGGCAGAAGCAGT GAAGGTTCTTCTCTGTGTGGGTGCCCTGCCCACCCCCTCCTTTGCCTGTGTCCTCCCGGCCTGGATCCATGGCTGACTCTGCCTGGAGGC CATTTGTGCCTGCCTCTGTGCTGCCGCAGGAGGGCAGGCCGCAAGTGGGGTTGGTGGGGGTCGAGCGGGCAGCACGGTGCAGCGGTGCAG TGGCAAGGGGGGCTACTTGTGTGGCATAAGCTAGAGGAGCCGGTGCCGCCTGAATGCCGAGCTAACTGTTGCCACTCTCCTCCCCAGACT ATGAAATCCCTGGAGAATTTTTGGTGACATGCACTGAGCCAAGGTGATGGACTGTATATTTGAGGAAAGACAAACAAAGAAACAAAATTA AAATGGAATTGGAGGCCGAACGCTGCACAGCTGCCCTCTCTCTCACCCAGTAAATGCAGAAAGCTCTTAGGACAGACAGAAAACCTGCCA TGGGGCTGCTTCCCTCCCTCGCAGGGCTGGCGGAGGCTCCGCATCGCCTCTCTCCTAGGATACAGAAACCATGGCAACGAAAGTAGAATG TAAAACTCGCAGCAGATATCAGTGGGAAGGGCTGGGGGAGGGGGCACCCAGCTGCCTTTCCTCCCTCACAGGAGCCACCACCAGCCACCT CTCAGGAGAAGCCAGAGGCCCTGGCCAAAGATAGGAGGAAGAAAGAGAACTCTCCATAGAATGTAATTTATAGATGCGTGTATATGTATA TATATCTATTTATATGTAAATAGGCATATATGAAGATATATATATATATAGTCTACTTTTTAAACTCTGCAGGGATTTGGTTAAGTTGTT GAGCTGATTTCTTCCATGTTTTAGAAAATGAGGCCTGTTTGGGGAAGGTACCCTGGTGATGTTTTTGCTAGACATTAGCTGTAGCTGACA GCATAAGGAGAGTCGCATCAGAGCTTTTCACAGCCCCCCGAAACCCCAGCCTGGTTTTGATGGCAGCAGTAATCATGATAGTGTGAACCC GCGAAGGCCTCAGGATTATGGTTAACCTGGAGAGGAGCAGGCCATGGAGGCAGGTGCCAGGTCAGTATTGAGTCACAGTAGAGGCCCCAC AAGGACCTGCTTGGGTGAGACCACCTCTCCCCTCTCAGCAGCGCTGGTGGGCTCTTTGTCCTGGTGCCCAGGAGCCCTCCAGCCCCCTGC CCACAGAAGGGAAGGCCTGCAGAGGGGGCCAGGATCTACCTAACCATTTCCCCACCCCTAAGTCCCTCAGTGGGCTTTGCCTTATAGGTG CCACAGGGCACAGCTCCATCATTGCCACTGGTTTTTCCTAAGTCATGCACCAAGGACTTCAGAAAGTTCTTCCTCCGAGTCAGTCAGTGG TGCCGGGACCCCAGGGCAGCCTCCTCGACTCCTGAAGAAAAGGCAGTGCCCGTGGCTGCCTCTGTCTTCACTCGCTGTTGATGTGACCGC CAGGCCTCCTCTCGTACCTTGGACAAAGGATACACCTGAACCAGAATAGTTTTCTTACCCTCACATTGAAATGAGGATTTTGCTTAAAAC AGCACTTGCCGCCAGTGGGAGGAGGGAGGTTTTATTTATTCCCACAGTTTCTCCTGGGCCTTCTGGAATGACCATGTTTTCCTGTGGCGG TGGGTGTGTCATTGCGCCCGCCGTCTTCCAAAGCCTTACTTCCCCAAGCTGCCAGCCAGGAGGTGATAACCACCCTCCCAGAGTTTCTCT CGGCTCTTTTTTTAAAAGTCCCCCAACAAATAGGATTCTTGCTGGGAAAGGAAGTTCGGTAAGGAAATGTCAAATCTGGTTTTTAAACAA GGTCCAACCCTGCAATGAAGCAGCCACTTCAGCCCAGAGAGATTATAAGAACTGATGTGGCCAGAGTGCCTACCCACTGTGGCCCCGGTG CTCTGCCCCCACGCCCCGACCATCTGGTCTTGGTAGATGTCCCTAGACGGGCTGAGCCATGTGCAATAAGAACATAGATCCTAAAGGATC >53569_53569_1_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000361114_DNAJB12_chr10_74096454_ENST00000338820_length(amino acids)=324AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTG -------------------------------------------------------------- >53569_53569_2_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000361114_DNAJB12_chr10_74096454_ENST00000394903_length(transcript)=3143nt_BP=1030nt GGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTT GGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCA GATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGA ATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAA GACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGAT TCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGAC ACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGG AAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGA CTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGT AGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAA CACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGA ATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGGTCCGTGGGCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCT ACTATGTGGGAGACACTTTCTCCGAAGAGTACACAGGCTCCAGCCTCAAAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACC TCCGGAACAACTGCTGGAAGGAGAAGCAGCAGAAGGAAGGCTTGCTGTACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAG CACAGAAGATGGGCACCCCCAGCTGCAGCCGACTGTCAGAGGTGCAGGCCTCCCTGCATGGATAGTCCTGGGCCAGCCACACCACCGAGG TCCAAACTATGAAATCCCTGGAGAATTTTTGGTGACATGCACTGAGCCAAGGTGATGGACTGTATATTTGAGGAAAGACAAACAAAGAAA CAAAATTAAAATGGAATTGGAGGCCGAACGCTGCACAGCTGCCCTCTCTCTCACCCAGTAAATGCAGAAAGCTCTTAGGACAGACAGAAA ACCTGCCATGGGGCTGCTTCCCTCCCTCGCAGGGCTGGCGGAGGCTCCGCATCGCCTCTCTCCTAGGATACAGAAACCATGGCAACGAAA GTAGAATGTAAAACTCGCAGCAGATATCAGTGGGAAGGGCTGGGGGAGGGGGCACCCAGCTGCCTTTCCTCCCTCACAGGAGCCACCACC AGCCACCTCTCAGGAGAAGCCAGAGGCCCTGGCCAAAGATAGGAGGAAGAAAGAGAACTCTCCATAGAATGTAATTTATAGATGCGTGTA TATGTATATATATCTATTTATATGTAAATAGGCATATATGAAGATATATATATATATAGTCTACTTTTTAAACTCTGCAGGGATTTGGTT AAGTTGTTGAGCTGATTTCTTCCATGTTTTAGAAAATGAGGCCTGTTTGGGGAAGGTACCCTGGTGATGTTTTTGCTAGACATTAGCTGT AGCTGACAGCATAAGGAGAGTCGCATCAGAGCTTTTCACAGCCCCCCGAAACCCCAGCCTGGTTTTGATGGCAGCAGTAATCATGATAGT GTGAACCCGCGAAGGCCTCAGGATTATGGTTAACCTGGAGAGGAGCAGGCCATGGAGGCAGGTGCCAGGTCAGTATTGAGTCACAGTAGA GGCCCCACAAGGACCTGCTTGGGTGAGACCACCTCTCCCCTCTCAGCAGCGCTGGTGGGCTCTTTGTCCTGGTGCCCAGGAGCCCTCCAG CCCCCTGCCCACAGAAGGGAAGGCCTGCAGAGGGGGCCAGGATCTACCTAACCATTTCCCCACCCCTAAGTCCCTCAGTGGGCTTTGCCT TATAGGTGCCACAGGGCACAGCTCCATCATTGCCACTGGTTTTTCCTAAGTCATGCACCAAGGACTTCAGAAAGTTCTTCCTCCGAGTCA GTCAGTGGTGCCGGGACCCCAGGGCAGCCTCCTCGACTCCTGAAGAAAAGGCAGTGCCCGTGGCTGCCTCTGTCTTCACTCGCTGTTGAT GTGACCGCCAGGCCTCCTCTCGTACCTTGGACAAAGGATACACCTGAACCAGAATAGTTTTCTTACCCTCACATTGAAATGAGGATTTTG CTTAAAACAGCACTTGCCGCCAGTGGGAGGAGGGAGGTTTTATTTATTCCCACAGTTTCTCCTGGGCCTTCTGGAATGACCATGTTTTCC TGTGGCGGTGGGTGTGTCATTGCGCCCGCCGTCTTCCAAAGCCTTACTTCCCCAAGCTGCCAGCCAGGAGGTGATAACCACCCTCCCAGA GTTTCTCTCGGCTCTTTTTTTAAAAGTCCCCCAACAAATAGGATTCTTGCTGGGAAAGGAAGTTCGGTAAGGAAATGTCAAATCTGGTTT TTAAACAAGGTCCAACCCTGCAATGAAGCAGCCACTTCAGCCCAGAGAGATTATAAGAACTGATGTGGCCAGAGTGCCTACCCACTGTGG CCCCGGTGCTCTGCCCCCACGCCCCGACCATCTGGTCTTGGTAGATGTCCCTAGACGGGCTGAGCCATGTGCAATAAGAACATAGATCCT >53569_53569_2_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000361114_DNAJB12_chr10_74096454_ENST00000394903_length(amino acids)=324AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTG -------------------------------------------------------------- >53569_53569_3_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000361114_DNAJB12_chr10_74096454_ENST00000444643_length(transcript)=3142nt_BP=1030nt GGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTT GGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCA GATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGA ATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAA GACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGAT TCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGAC ACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGG AAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGA CTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGT AGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAA CACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGA ATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGGTCCGTGGGCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCT ACTATGTGGGAGACACTTTCTCCGAAGAGTACACAGGCTCCAGCCTCAAAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACC TCCGGAACAACTGCTGGAAGGAGAAGCAGCAGAAGGAAGGCTTGCTGTACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAG CACAGAAGATGGGCACCCCCAGCTGCAGCCGACTGTCAGAGGTGCAGGCCTCCCTGCATGGATAGTCCTGGGCCAGCCACACCACCGAGG TCCAAACTATGAAATCCCTGGAGAATTTTTGGTGACATGCACTGAGCCAAGGTGATGGACTGTATATTTGAGGAAAGACAAACAAAGAAA CAAAATTAAAATGGAATTGGAGGCCGAACGCTGCACAGCTGCCCTCTCTCTCACCCAGTAAATGCAGAAAGCTCTTAGGACAGACAGAAA ACCTGCCATGGGGCTGCTTCCCTCCCTCGCAGGGCTGGCGGAGGCTCCGCATCGCCTCTCTCCTAGGATACAGAAACCATGGCAACGAAA GTAGAATGTAAAACTCGCAGCAGATATCAGTGGGAAGGGCTGGGGGAGGGGGCACCCAGCTGCCTTTCCTCCCTCACAGGAGCCACCACC AGCCACCTCTCAGGAGAAGCCAGAGGCCCTGGCCAAAGATAGGAGGAAGAAAGAGAACTCTCCATAGAATGTAATTTATAGATGCGTGTA TATGTATATATATCTATTTATATGTAAATAGGCATATATGAAGATATATATATATATAGTCTACTTTTTAAACTCTGCAGGGATTTGGTT AAGTTGTTGAGCTGATTTCTTCCATGTTTTAGAAAATGAGGCCTGTTTGGGGAAGGTACCCTGGTGATGTTTTTGCTAGACATTAGCTGT AGCTGACAGCATAAGGAGAGTCGCATCAGAGCTTTTCACAGCCCCCCGAAACCCCAGCCTGGTTTTGATGGCAGCAGTAATCATGATAGT GTGAACCCGCGAAGGCCTCAGGATTATGGTTAACCTGGAGAGGAGCAGGCCATGGAGGCAGGTGCCAGGTCAGTATTGAGTCACAGTAGA GGCCCCACAAGGACCTGCTTGGGTGAGACCACCTCTCCCCTCTCAGCAGCGCTGGTGGGCTCTTTGTCCTGGTGCCCAGGAGCCCTCCAG CCCCCTGCCCACAGAAGGGAAGGCCTGCAGAGGGGGCCAGGATCTACCTAACCATTTCCCCACCCCTAAGTCCCTCAGTGGGCTTTGCCT TATAGGTGCCACAGGGCACAGCTCCATCATTGCCACTGGTTTTTCCTAAGTCATGCACCAAGGACTTCAGAAAGTTCTTCCTCCGAGTCA GTCAGTGGTGCCGGGACCCCAGGGCAGCCTCCTCGACTCCTGAAGAAAAGGCAGTGCCCGTGGCTGCCTCTGTCTTCACTCGCTGTTGAT GTGACCGCCAGGCCTCCTCTCGTACCTTGGACAAAGGATACACCTGAACCAGAATAGTTTTCTTACCCTCACATTGAAATGAGGATTTTG CTTAAAACAGCACTTGCCGCCAGTGGGAGGAGGGAGGTTTTATTTATTCCCACAGTTTCTCCTGGGCCTTCTGGAATGACCATGTTTTCC TGTGGCGGTGGGTGTGTCATTGCGCCCGCCGTCTTCCAAAGCCTTACTTCCCCAAGCTGCCAGCCAGGAGGTGATAACCACCCTCCCAGA GTTTCTCTCGGCTCTTTTTTTAAAAGTCCCCCAACAAATAGGATTCTTGCTGGGAAAGGAAGTTCGGTAAGGAAATGTCAAATCTGGTTT TTAAACAAGGTCCAACCCTGCAATGAAGCAGCCACTTCAGCCCAGAGAGATTATAAGAACTGATGTGGCCAGAGTGCCTACCCACTGTGG CCCCGGTGCTCTGCCCCCACGCCCCGACCATCTGGTCTTGGTAGATGTCCCTAGACGGGCTGAGCCATGTGCAATAAGAACATAGATCCT >53569_53569_3_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000361114_DNAJB12_chr10_74096454_ENST00000444643_length(amino acids)=324AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTG -------------------------------------------------------------- >53569_53569_4_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000361114_DNAJB12_chr10_74096454_ENST00000461919_length(transcript)=1838nt_BP=1030nt GGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTT GGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCA GATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGA ATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAA GACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGAT TCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGAC ACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGG AAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGA CTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGT AGATATGGAAGAATTTGAACAGGTTCAGAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAA CACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGA ATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGGTCCGTGGGCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCT ACTATGTGGGAGACACTTTCTCCGAAGAGTACACAGGCTCCAGCCTCAAAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACC TCCGGAACAACTGCTGGAAGGAGAAGCAGCAGAAGGAAGGCTTGCTGTACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAG CACAGAAGATGGGCACCCCCAGCTGCAGCCGACTGTCAGAGACTATGAAATCCCTGGAGAATTTTTGGTGACATGCACTGAGCCAAGGTG ATGGACTGTATATTTGAGGAAAGACAAACAAAGAAACAAAATTAAAATGGAATTGGAGGCCGAACGCTGCACAGCTGCCCTCTCTCTCAC CCAGTAAATGCAGAAAGCTCTTAGGACAGACAGAAAACCTGCCATGGGGCTGCTTCCCTCCCTCGCAGGGCTGGCGGAGGCTCCGCATCG CCTCTCTCCTAGGATACAGAAACCATGGCAACGAAAGTAGAATGTAAAACTCGCAGCAGATATCAGTGGGAAGGGCTGGGGGAGGGGGCA CCCAGCTGCCTTTCCTCCCTCACAGGAGCCACCACCAGCCACCTCTCAGGAGAAGCCAGAGGCCCTGGCCAAAGATAGGAGGAAGAAAGA GAACTCTCCATAGAATGTAATTTATAGATGCGTGTATATGTATATATATCTATTTATATGTAAATAGGCATATATGAAGATATATATATA >53569_53569_4_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000361114_DNAJB12_chr10_74096454_ENST00000461919_length(amino acids)=324AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTG -------------------------------------------------------------- >53569_53569_5_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000398761_DNAJB12_chr10_74096454_ENST00000338820_length(transcript)=4347nt_BP=1072nt AGGCCCAGCGGCTAGGAGAGTCACGTGAGAGTGGGCGGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGG GCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGG TTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGC AAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAA TAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATT CAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGT CATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTT GGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAATAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTAT ATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGA AATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAATTAGCATCATTCGCTCCCAAAC CAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGG AGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGGTCCGTGG GCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCTACTATGTGGGAGACACTTTCTCCGAAGAGTACACAGGCTCCAGCCTCA AAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACCTCCGGAACAACTGCTGGAAGGAGAAGCAGCAGAAGGAAGGCTTGCTGT ACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAGCACAGAAGATGGGCACCCCCAGCTGCAGCCGACTGTCAGAGGTGCAGG CCTCCCTGCATGGATAGTCCTGGGCCAGCCACACCACCGAGGTCCAAGTATGAGCCAGGGCTGCCTCCACCCTGCAACTCCTGGCAGCTT TGGCCCTGGTCATGAGCAGAGGAGGGAGGGGGAGAAAGGGAGGAAGCCTGGTGATTGTGGCAAAGACTCCTGTCCCCAGCCTGACCTCCA GCCTCCAGAGACCGAGCAGCTGTGGGGCCTGCTGGGAAACCAAGGTCGGTTTCCGCCCTCTAGCGATGCTGTCCTCCCCACTCCTCCGCT CTGCTCCCTGGCTCCAGGGGTGTGGGGGACCCCAGAACCAGGCAGAGTGGGAACTTGAAACTGTTGCTGAGGGCCACCCGGGGCTTCTTG GTCCACTCCAGCCATCAGTCAGCACGGCCCTTTCTCCAGCACAGCAGACTATTGTCCGTGCCCTGGTATTTAGGCCATCACATATGGTGG GGCCCAAGAGAGCCCCATATGCACACTGCCTGCCTGATACCAGGAAGAACCATGTGGGAATAGGTGGGCCAAGAGCCCTCCCCTTTCTCC ATCCCTCCAGCTAGGAGGAAATGGAGCAAGATGAACAGGCAGCCACGAGGTGGGTGGGAGCTGGCAGTCTTGGTGGCGGCAGGGGCCGCG GGCCCTGACCACCCCCCTCTGGTGGGATCTGAGGCACTCTCTCGAATGCCGTCACACCTGGCAGCCTGGAAGCCACAGGCATCCGGCCTT GCCCAGGCATCTCGCCTGCGGTCTGAGGAAGGGAACAGAAGGTCATGAGTTCAGGGTCAGACGCAGCCGCTCAGCACAGGAGGGGTGGAG GGGAAATGAGAGTTGCTGGTAGCAGGCTCCCTCCTTCTGCAGCCCGGCGAATGGGGGCGCTGGGCTCTGTTCCCAGCGTTTGCCAGAGGT GGCCACTTCAGCCAAGCCCAGAGAAGTGTGGGCAGAAGCAGTGAAGGTTCTTCTCTGTGTGGGTGCCCTGCCCACCCCCTCCTTTGCCTG TGTCCTCCCGGCCTGGATCCATGGCTGACTCTGCCTGGAGGCCATTTGTGCCTGCCTCTGTGCTGCCGCAGGAGGGCAGGCCGCAAGTGG GGTTGGTGGGGGTCGAGCGGGCAGCACGGTGCAGCGGTGCAGTGGCAAGGGGGGCTACTTGTGTGGCATAAGCTAGAGGAGCCGGTGCCG CCTGAATGCCGAGCTAACTGTTGCCACTCTCCTCCCCAGACTATGAAATCCCTGGAGAATTTTTGGTGACATGCACTGAGCCAAGGTGAT GGACTGTATATTTGAGGAAAGACAAACAAAGAAACAAAATTAAAATGGAATTGGAGGCCGAACGCTGCACAGCTGCCCTCTCTCTCACCC AGTAAATGCAGAAAGCTCTTAGGACAGACAGAAAACCTGCCATGGGGCTGCTTCCCTCCCTCGCAGGGCTGGCGGAGGCTCCGCATCGCC TCTCTCCTAGGATACAGAAACCATGGCAACGAAAGTAGAATGTAAAACTCGCAGCAGATATCAGTGGGAAGGGCTGGGGGAGGGGGCACC CAGCTGCCTTTCCTCCCTCACAGGAGCCACCACCAGCCACCTCTCAGGAGAAGCCAGAGGCCCTGGCCAAAGATAGGAGGAAGAAAGAGA ACTCTCCATAGAATGTAATTTATAGATGCGTGTATATGTATATATATCTATTTATATGTAAATAGGCATATATGAAGATATATATATATA TAGTCTACTTTTTAAACTCTGCAGGGATTTGGTTAAGTTGTTGAGCTGATTTCTTCCATGTTTTAGAAAATGAGGCCTGTTTGGGGAAGG TACCCTGGTGATGTTTTTGCTAGACATTAGCTGTAGCTGACAGCATAAGGAGAGTCGCATCAGAGCTTTTCACAGCCCCCCGAAACCCCA GCCTGGTTTTGATGGCAGCAGTAATCATGATAGTGTGAACCCGCGAAGGCCTCAGGATTATGGTTAACCTGGAGAGGAGCAGGCCATGGA GGCAGGTGCCAGGTCAGTATTGAGTCACAGTAGAGGCCCCACAAGGACCTGCTTGGGTGAGACCACCTCTCCCCTCTCAGCAGCGCTGGT GGGCTCTTTGTCCTGGTGCCCAGGAGCCCTCCAGCCCCCTGCCCACAGAAGGGAAGGCCTGCAGAGGGGGCCAGGATCTACCTAACCATT TCCCCACCCCTAAGTCCCTCAGTGGGCTTTGCCTTATAGGTGCCACAGGGCACAGCTCCATCATTGCCACTGGTTTTTCCTAAGTCATGC ACCAAGGACTTCAGAAAGTTCTTCCTCCGAGTCAGTCAGTGGTGCCGGGACCCCAGGGCAGCCTCCTCGACTCCTGAAGAAAAGGCAGTG CCCGTGGCTGCCTCTGTCTTCACTCGCTGTTGATGTGACCGCCAGGCCTCCTCTCGTACCTTGGACAAAGGATACACCTGAACCAGAATA GTTTTCTTACCCTCACATTGAAATGAGGATTTTGCTTAAAACAGCACTTGCCGCCAGTGGGAGGAGGGAGGTTTTATTTATTCCCACAGT TTCTCCTGGGCCTTCTGGAATGACCATGTTTTCCTGTGGCGGTGGGTGTGTCATTGCGCCCGCCGTCTTCCAAAGCCTTACTTCCCCAAG CTGCCAGCCAGGAGGTGATAACCACCCTCCCAGAGTTTCTCTCGGCTCTTTTTTTAAAAGTCCCCCAACAAATAGGATTCTTGCTGGGAA AGGAAGTTCGGTAAGGAAATGTCAAATCTGGTTTTTAAACAAGGTCCAACCCTGCAATGAAGCAGCCACTTCAGCCCAGAGAGATTATAA GAACTGATGTGGCCAGAGTGCCTACCCACTGTGGCCCCGGTGCTCTGCCCCCACGCCCCGACCATCTGGTCTTGGTAGATGTCCCTAGAC GGGCTGAGCCATGTGCAATAAGAACATAGATCCTAAAGGATCCTCTGGAAGCTGTATTTCTTGAATTAGAATTCTCAAATTGTACATCTG >53569_53569_5_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000398761_DNAJB12_chr10_74096454_ENST00000338820_length(amino acids)=326AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKNKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPT -------------------------------------------------------------- >53569_53569_6_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000398761_DNAJB12_chr10_74096454_ENST00000394903_length(transcript)=3185nt_BP=1072nt AGGCCCAGCGGCTAGGAGAGTCACGTGAGAGTGGGCGGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGG GCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGG TTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGC AAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAA TAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATT CAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGT CATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTT GGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAATAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTAT ATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGA AATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAATTAGCATCATTCGCTCCCAAAC CAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGG AGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGGTCCGTGG GCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCTACTATGTGGGAGACACTTTCTCCGAAGAGTACACAGGCTCCAGCCTCA AAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACCTCCGGAACAACTGCTGGAAGGAGAAGCAGCAGAAGGAAGGCTTGCTGT ACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAGCACAGAAGATGGGCACCCCCAGCTGCAGCCGACTGTCAGAGGTGCAGG CCTCCCTGCATGGATAGTCCTGGGCCAGCCACACCACCGAGGTCCAAACTATGAAATCCCTGGAGAATTTTTGGTGACATGCACTGAGCC AAGGTGATGGACTGTATATTTGAGGAAAGACAAACAAAGAAACAAAATTAAAATGGAATTGGAGGCCGAACGCTGCACAGCTGCCCTCTC TCTCACCCAGTAAATGCAGAAAGCTCTTAGGACAGACAGAAAACCTGCCATGGGGCTGCTTCCCTCCCTCGCAGGGCTGGCGGAGGCTCC GCATCGCCTCTCTCCTAGGATACAGAAACCATGGCAACGAAAGTAGAATGTAAAACTCGCAGCAGATATCAGTGGGAAGGGCTGGGGGAG GGGGCACCCAGCTGCCTTTCCTCCCTCACAGGAGCCACCACCAGCCACCTCTCAGGAGAAGCCAGAGGCCCTGGCCAAAGATAGGAGGAA GAAAGAGAACTCTCCATAGAATGTAATTTATAGATGCGTGTATATGTATATATATCTATTTATATGTAAATAGGCATATATGAAGATATA TATATATATAGTCTACTTTTTAAACTCTGCAGGGATTTGGTTAAGTTGTTGAGCTGATTTCTTCCATGTTTTAGAAAATGAGGCCTGTTT GGGGAAGGTACCCTGGTGATGTTTTTGCTAGACATTAGCTGTAGCTGACAGCATAAGGAGAGTCGCATCAGAGCTTTTCACAGCCCCCCG AAACCCCAGCCTGGTTTTGATGGCAGCAGTAATCATGATAGTGTGAACCCGCGAAGGCCTCAGGATTATGGTTAACCTGGAGAGGAGCAG GCCATGGAGGCAGGTGCCAGGTCAGTATTGAGTCACAGTAGAGGCCCCACAAGGACCTGCTTGGGTGAGACCACCTCTCCCCTCTCAGCA GCGCTGGTGGGCTCTTTGTCCTGGTGCCCAGGAGCCCTCCAGCCCCCTGCCCACAGAAGGGAAGGCCTGCAGAGGGGGCCAGGATCTACC TAACCATTTCCCCACCCCTAAGTCCCTCAGTGGGCTTTGCCTTATAGGTGCCACAGGGCACAGCTCCATCATTGCCACTGGTTTTTCCTA AGTCATGCACCAAGGACTTCAGAAAGTTCTTCCTCCGAGTCAGTCAGTGGTGCCGGGACCCCAGGGCAGCCTCCTCGACTCCTGAAGAAA AGGCAGTGCCCGTGGCTGCCTCTGTCTTCACTCGCTGTTGATGTGACCGCCAGGCCTCCTCTCGTACCTTGGACAAAGGATACACCTGAA CCAGAATAGTTTTCTTACCCTCACATTGAAATGAGGATTTTGCTTAAAACAGCACTTGCCGCCAGTGGGAGGAGGGAGGTTTTATTTATT CCCACAGTTTCTCCTGGGCCTTCTGGAATGACCATGTTTTCCTGTGGCGGTGGGTGTGTCATTGCGCCCGCCGTCTTCCAAAGCCTTACT TCCCCAAGCTGCCAGCCAGGAGGTGATAACCACCCTCCCAGAGTTTCTCTCGGCTCTTTTTTTAAAAGTCCCCCAACAAATAGGATTCTT GCTGGGAAAGGAAGTTCGGTAAGGAAATGTCAAATCTGGTTTTTAAACAAGGTCCAACCCTGCAATGAAGCAGCCACTTCAGCCCAGAGA GATTATAAGAACTGATGTGGCCAGAGTGCCTACCCACTGTGGCCCCGGTGCTCTGCCCCCACGCCCCGACCATCTGGTCTTGGTAGATGT CCCTAGACGGGCTGAGCCATGTGCAATAAGAACATAGATCCTAAAGGATCCTCTGGAAGCTGTATTTCTTGAATTAGAATTCTCAAATTG >53569_53569_6_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000398761_DNAJB12_chr10_74096454_ENST00000394903_length(amino acids)=326AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKNKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPT -------------------------------------------------------------- >53569_53569_7_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000398761_DNAJB12_chr10_74096454_ENST00000444643_length(transcript)=3184nt_BP=1072nt AGGCCCAGCGGCTAGGAGAGTCACGTGAGAGTGGGCGGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGG GCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGG TTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGC AAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAA TAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATT CAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGT CATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTT GGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAATAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTAT ATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGA AATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAATTAGCATCATTCGCTCCCAAAC CAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGG AGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGGTCCGTGG GCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCTACTATGTGGGAGACACTTTCTCCGAAGAGTACACAGGCTCCAGCCTCA AAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACCTCCGGAACAACTGCTGGAAGGAGAAGCAGCAGAAGGAAGGCTTGCTGT ACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAGCACAGAAGATGGGCACCCCCAGCTGCAGCCGACTGTCAGAGGTGCAGG CCTCCCTGCATGGATAGTCCTGGGCCAGCCACACCACCGAGGTCCAAACTATGAAATCCCTGGAGAATTTTTGGTGACATGCACTGAGCC AAGGTGATGGACTGTATATTTGAGGAAAGACAAACAAAGAAACAAAATTAAAATGGAATTGGAGGCCGAACGCTGCACAGCTGCCCTCTC TCTCACCCAGTAAATGCAGAAAGCTCTTAGGACAGACAGAAAACCTGCCATGGGGCTGCTTCCCTCCCTCGCAGGGCTGGCGGAGGCTCC GCATCGCCTCTCTCCTAGGATACAGAAACCATGGCAACGAAAGTAGAATGTAAAACTCGCAGCAGATATCAGTGGGAAGGGCTGGGGGAG GGGGCACCCAGCTGCCTTTCCTCCCTCACAGGAGCCACCACCAGCCACCTCTCAGGAGAAGCCAGAGGCCCTGGCCAAAGATAGGAGGAA GAAAGAGAACTCTCCATAGAATGTAATTTATAGATGCGTGTATATGTATATATATCTATTTATATGTAAATAGGCATATATGAAGATATA TATATATATAGTCTACTTTTTAAACTCTGCAGGGATTTGGTTAAGTTGTTGAGCTGATTTCTTCCATGTTTTAGAAAATGAGGCCTGTTT GGGGAAGGTACCCTGGTGATGTTTTTGCTAGACATTAGCTGTAGCTGACAGCATAAGGAGAGTCGCATCAGAGCTTTTCACAGCCCCCCG AAACCCCAGCCTGGTTTTGATGGCAGCAGTAATCATGATAGTGTGAACCCGCGAAGGCCTCAGGATTATGGTTAACCTGGAGAGGAGCAG GCCATGGAGGCAGGTGCCAGGTCAGTATTGAGTCACAGTAGAGGCCCCACAAGGACCTGCTTGGGTGAGACCACCTCTCCCCTCTCAGCA GCGCTGGTGGGCTCTTTGTCCTGGTGCCCAGGAGCCCTCCAGCCCCCTGCCCACAGAAGGGAAGGCCTGCAGAGGGGGCCAGGATCTACC TAACCATTTCCCCACCCCTAAGTCCCTCAGTGGGCTTTGCCTTATAGGTGCCACAGGGCACAGCTCCATCATTGCCACTGGTTTTTCCTA AGTCATGCACCAAGGACTTCAGAAAGTTCTTCCTCCGAGTCAGTCAGTGGTGCCGGGACCCCAGGGCAGCCTCCTCGACTCCTGAAGAAA AGGCAGTGCCCGTGGCTGCCTCTGTCTTCACTCGCTGTTGATGTGACCGCCAGGCCTCCTCTCGTACCTTGGACAAAGGATACACCTGAA CCAGAATAGTTTTCTTACCCTCACATTGAAATGAGGATTTTGCTTAAAACAGCACTTGCCGCCAGTGGGAGGAGGGAGGTTTTATTTATT CCCACAGTTTCTCCTGGGCCTTCTGGAATGACCATGTTTTCCTGTGGCGGTGGGTGTGTCATTGCGCCCGCCGTCTTCCAAAGCCTTACT TCCCCAAGCTGCCAGCCAGGAGGTGATAACCACCCTCCCAGAGTTTCTCTCGGCTCTTTTTTTAAAAGTCCCCCAACAAATAGGATTCTT GCTGGGAAAGGAAGTTCGGTAAGGAAATGTCAAATCTGGTTTTTAAACAAGGTCCAACCCTGCAATGAAGCAGCCACTTCAGCCCAGAGA GATTATAAGAACTGATGTGGCCAGAGTGCCTACCCACTGTGGCCCCGGTGCTCTGCCCCCACGCCCCGACCATCTGGTCTTGGTAGATGT CCCTAGACGGGCTGAGCCATGTGCAATAAGAACATAGATCCTAAAGGATCCTCTGGAAGCTGTATTTCTTGAATTAGAATTCTCAAATTG >53569_53569_7_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000398761_DNAJB12_chr10_74096454_ENST00000444643_length(amino acids)=326AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKNKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPT -------------------------------------------------------------- >53569_53569_8_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000398761_DNAJB12_chr10_74096454_ENST00000461919_length(transcript)=1880nt_BP=1072nt AGGCCCAGCGGCTAGGAGAGTCACGTGAGAGTGGGCGGAGGGGGTGGAGGTTTGTCTCCGCTGTTTCATCTCTATGGCTGTCAGAGGTGG GCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCACTTTCTGCTTTGGCAGAACTGGCTGTGGG TTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGGCTTTCCTGGGAGCATCTGCAGTAACTGC AAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAAAAAGTGACATCGGTGATAAAGGGAAGAA TAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAGAAGAGAAAAAGAAGAAACGTTCTGGATT CAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAATCTTCCGATATTTTGCCACCTTGAAAGT CATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAACACCCAATGAAAAACAACCAGAACACTT GGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAATAAGAAAATTTCCCAGGAACGAGAAAAATTTGCTGATGAAGGCAGTAT ATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTTCCACTCCTCAGAGAAATTTTGA AATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAATTAGCATCATTCGCTCCCAAAC CAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAGCCCTCACAACCTACTTTTTTGG AGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATGTTCTGAAGCTTGAGGTCCGTGG GCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCTACTATGTGGGAGACACTTTCTCCGAAGAGTACACAGGCTCCAGCCTCA AAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACCTCCGGAACAACTGCTGGAAGGAGAAGCAGCAGAAGGAAGGCTTGCTGT ACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAGCACAGAAGATGGGCACCCCCAGCTGCAGCCGACTGTCAGAGACTATGA AATCCCTGGAGAATTTTTGGTGACATGCACTGAGCCAAGGTGATGGACTGTATATTTGAGGAAAGACAAACAAAGAAACAAAATTAAAAT GGAATTGGAGGCCGAACGCTGCACAGCTGCCCTCTCTCTCACCCAGTAAATGCAGAAAGCTCTTAGGACAGACAGAAAACCTGCCATGGG GCTGCTTCCCTCCCTCGCAGGGCTGGCGGAGGCTCCGCATCGCCTCTCTCCTAGGATACAGAAACCATGGCAACGAAAGTAGAATGTAAA ACTCGCAGCAGATATCAGTGGGAAGGGCTGGGGGAGGGGGCACCCAGCTGCCTTTCCTCCCTCACAGGAGCCACCACCAGCCACCTCTCA GGAGAAGCCAGAGGCCCTGGCCAAAGATAGGAGGAAGAAAGAGAACTCTCCATAGAATGTAATTTATAGATGCGTGTATATGTATATATA >53569_53569_8_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000398761_DNAJB12_chr10_74096454_ENST00000461919_length(amino acids)=326AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKNKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPT -------------------------------------------------------------- >53569_53569_9_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000401998_DNAJB12_chr10_74096454_ENST00000338820_length(transcript)=4279nt_BP=1004nt GTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCAC TTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGG CTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAA AAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAG AAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAA TCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAA CACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAAAATTTCCCAGGAACGAGAAA AATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTT CCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAA TTAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAG CCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATG TTCTGAAGCTTGAGGTCCGTGGGCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCTACTATGTGGGAGACACTTTCTCCGAA GAGTACACAGGCTCCAGCCTCAAAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACCTCCGGAACAACTGCTGGAAGGAGAAG CAGCAGAAGGAAGGCTTGCTGTACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAGCACAGAAGATGGGCACCCCCAGCTGC AGCCGACTGTCAGAGGTGCAGGCCTCCCTGCATGGATAGTCCTGGGCCAGCCACACCACCGAGGTCCAAGTATGAGCCAGGGCTGCCTCC ACCCTGCAACTCCTGGCAGCTTTGGCCCTGGTCATGAGCAGAGGAGGGAGGGGGAGAAAGGGAGGAAGCCTGGTGATTGTGGCAAAGACT CCTGTCCCCAGCCTGACCTCCAGCCTCCAGAGACCGAGCAGCTGTGGGGCCTGCTGGGAAACCAAGGTCGGTTTCCGCCCTCTAGCGATG CTGTCCTCCCCACTCCTCCGCTCTGCTCCCTGGCTCCAGGGGTGTGGGGGACCCCAGAACCAGGCAGAGTGGGAACTTGAAACTGTTGCT GAGGGCCACCCGGGGCTTCTTGGTCCACTCCAGCCATCAGTCAGCACGGCCCTTTCTCCAGCACAGCAGACTATTGTCCGTGCCCTGGTA TTTAGGCCATCACATATGGTGGGGCCCAAGAGAGCCCCATATGCACACTGCCTGCCTGATACCAGGAAGAACCATGTGGGAATAGGTGGG CCAAGAGCCCTCCCCTTTCTCCATCCCTCCAGCTAGGAGGAAATGGAGCAAGATGAACAGGCAGCCACGAGGTGGGTGGGAGCTGGCAGT CTTGGTGGCGGCAGGGGCCGCGGGCCCTGACCACCCCCCTCTGGTGGGATCTGAGGCACTCTCTCGAATGCCGTCACACCTGGCAGCCTG GAAGCCACAGGCATCCGGCCTTGCCCAGGCATCTCGCCTGCGGTCTGAGGAAGGGAACAGAAGGTCATGAGTTCAGGGTCAGACGCAGCC GCTCAGCACAGGAGGGGTGGAGGGGAAATGAGAGTTGCTGGTAGCAGGCTCCCTCCTTCTGCAGCCCGGCGAATGGGGGCGCTGGGCTCT GTTCCCAGCGTTTGCCAGAGGTGGCCACTTCAGCCAAGCCCAGAGAAGTGTGGGCAGAAGCAGTGAAGGTTCTTCTCTGTGTGGGTGCCC TGCCCACCCCCTCCTTTGCCTGTGTCCTCCCGGCCTGGATCCATGGCTGACTCTGCCTGGAGGCCATTTGTGCCTGCCTCTGTGCTGCCG CAGGAGGGCAGGCCGCAAGTGGGGTTGGTGGGGGTCGAGCGGGCAGCACGGTGCAGCGGTGCAGTGGCAAGGGGGGCTACTTGTGTGGCA TAAGCTAGAGGAGCCGGTGCCGCCTGAATGCCGAGCTAACTGTTGCCACTCTCCTCCCCAGACTATGAAATCCCTGGAGAATTTTTGGTG ACATGCACTGAGCCAAGGTGATGGACTGTATATTTGAGGAAAGACAAACAAAGAAACAAAATTAAAATGGAATTGGAGGCCGAACGCTGC ACAGCTGCCCTCTCTCTCACCCAGTAAATGCAGAAAGCTCTTAGGACAGACAGAAAACCTGCCATGGGGCTGCTTCCCTCCCTCGCAGGG CTGGCGGAGGCTCCGCATCGCCTCTCTCCTAGGATACAGAAACCATGGCAACGAAAGTAGAATGTAAAACTCGCAGCAGATATCAGTGGG AAGGGCTGGGGGAGGGGGCACCCAGCTGCCTTTCCTCCCTCACAGGAGCCACCACCAGCCACCTCTCAGGAGAAGCCAGAGGCCCTGGCC AAAGATAGGAGGAAGAAAGAGAACTCTCCATAGAATGTAATTTATAGATGCGTGTATATGTATATATATCTATTTATATGTAAATAGGCA TATATGAAGATATATATATATATAGTCTACTTTTTAAACTCTGCAGGGATTTGGTTAAGTTGTTGAGCTGATTTCTTCCATGTTTTAGAA AATGAGGCCTGTTTGGGGAAGGTACCCTGGTGATGTTTTTGCTAGACATTAGCTGTAGCTGACAGCATAAGGAGAGTCGCATCAGAGCTT TTCACAGCCCCCCGAAACCCCAGCCTGGTTTTGATGGCAGCAGTAATCATGATAGTGTGAACCCGCGAAGGCCTCAGGATTATGGTTAAC CTGGAGAGGAGCAGGCCATGGAGGCAGGTGCCAGGTCAGTATTGAGTCACAGTAGAGGCCCCACAAGGACCTGCTTGGGTGAGACCACCT CTCCCCTCTCAGCAGCGCTGGTGGGCTCTTTGTCCTGGTGCCCAGGAGCCCTCCAGCCCCCTGCCCACAGAAGGGAAGGCCTGCAGAGGG GGCCAGGATCTACCTAACCATTTCCCCACCCCTAAGTCCCTCAGTGGGCTTTGCCTTATAGGTGCCACAGGGCACAGCTCCATCATTGCC ACTGGTTTTTCCTAAGTCATGCACCAAGGACTTCAGAAAGTTCTTCCTCCGAGTCAGTCAGTGGTGCCGGGACCCCAGGGCAGCCTCCTC GACTCCTGAAGAAAAGGCAGTGCCCGTGGCTGCCTCTGTCTTCACTCGCTGTTGATGTGACCGCCAGGCCTCCTCTCGTACCTTGGACAA AGGATACACCTGAACCAGAATAGTTTTCTTACCCTCACATTGAAATGAGGATTTTGCTTAAAACAGCACTTGCCGCCAGTGGGAGGAGGG AGGTTTTATTTATTCCCACAGTTTCTCCTGGGCCTTCTGGAATGACCATGTTTTCCTGTGGCGGTGGGTGTGTCATTGCGCCCGCCGTCT TCCAAAGCCTTACTTCCCCAAGCTGCCAGCCAGGAGGTGATAACCACCCTCCCAGAGTTTCTCTCGGCTCTTTTTTTAAAAGTCCCCCAA CAAATAGGATTCTTGCTGGGAAAGGAAGTTCGGTAAGGAAATGTCAAATCTGGTTTTTAAACAAGGTCCAACCCTGCAATGAAGCAGCCA CTTCAGCCCAGAGAGATTATAAGAACTGATGTGGCCAGAGTGCCTACCCACTGTGGCCCCGGTGCTCTGCCCCCACGCCCCGACCATCTG GTCTTGGTAGATGTCCCTAGACGGGCTGAGCCATGTGCAATAAGAACATAGATCCTAAAGGATCCTCTGGAAGCTGTATTTCTTGAATTA >53569_53569_9_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000401998_DNAJB12_chr10_74096454_ENST00000338820_length(amino acids)=324AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPTTG -------------------------------------------------------------- >53569_53569_10_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000401998_DNAJB12_chr10_74096454_ENST00000394903_length(transcript)=3117nt_BP=1004nt GTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCAC TTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGG CTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAA AAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAG AAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAA TCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAA CACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAAAATTTCCCAGGAACGAGAAA AATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTT CCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAA TTAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAG CCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATG TTCTGAAGCTTGAGGTCCGTGGGCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCTACTATGTGGGAGACACTTTCTCCGAA GAGTACACAGGCTCCAGCCTCAAAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACCTCCGGAACAACTGCTGGAAGGAGAAG CAGCAGAAGGAAGGCTTGCTGTACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAGCACAGAAGATGGGCACCCCCAGCTGC AGCCGACTGTCAGAGGTGCAGGCCTCCCTGCATGGATAGTCCTGGGCCAGCCACACCACCGAGGTCCAAACTATGAAATCCCTGGAGAAT TTTTGGTGACATGCACTGAGCCAAGGTGATGGACTGTATATTTGAGGAAAGACAAACAAAGAAACAAAATTAAAATGGAATTGGAGGCCG AACGCTGCACAGCTGCCCTCTCTCTCACCCAGTAAATGCAGAAAGCTCTTAGGACAGACAGAAAACCTGCCATGGGGCTGCTTCCCTCCC TCGCAGGGCTGGCGGAGGCTCCGCATCGCCTCTCTCCTAGGATACAGAAACCATGGCAACGAAAGTAGAATGTAAAACTCGCAGCAGATA TCAGTGGGAAGGGCTGGGGGAGGGGGCACCCAGCTGCCTTTCCTCCCTCACAGGAGCCACCACCAGCCACCTCTCAGGAGAAGCCAGAGG CCCTGGCCAAAGATAGGAGGAAGAAAGAGAACTCTCCATAGAATGTAATTTATAGATGCGTGTATATGTATATATATCTATTTATATGTA AATAGGCATATATGAAGATATATATATATATAGTCTACTTTTTAAACTCTGCAGGGATTTGGTTAAGTTGTTGAGCTGATTTCTTCCATG TTTTAGAAAATGAGGCCTGTTTGGGGAAGGTACCCTGGTGATGTTTTTGCTAGACATTAGCTGTAGCTGACAGCATAAGGAGAGTCGCAT CAGAGCTTTTCACAGCCCCCCGAAACCCCAGCCTGGTTTTGATGGCAGCAGTAATCATGATAGTGTGAACCCGCGAAGGCCTCAGGATTA TGGTTAACCTGGAGAGGAGCAGGCCATGGAGGCAGGTGCCAGGTCAGTATTGAGTCACAGTAGAGGCCCCACAAGGACCTGCTTGGGTGA GACCACCTCTCCCCTCTCAGCAGCGCTGGTGGGCTCTTTGTCCTGGTGCCCAGGAGCCCTCCAGCCCCCTGCCCACAGAAGGGAAGGCCT GCAGAGGGGGCCAGGATCTACCTAACCATTTCCCCACCCCTAAGTCCCTCAGTGGGCTTTGCCTTATAGGTGCCACAGGGCACAGCTCCA TCATTGCCACTGGTTTTTCCTAAGTCATGCACCAAGGACTTCAGAAAGTTCTTCCTCCGAGTCAGTCAGTGGTGCCGGGACCCCAGGGCA GCCTCCTCGACTCCTGAAGAAAAGGCAGTGCCCGTGGCTGCCTCTGTCTTCACTCGCTGTTGATGTGACCGCCAGGCCTCCTCTCGTACC TTGGACAAAGGATACACCTGAACCAGAATAGTTTTCTTACCCTCACATTGAAATGAGGATTTTGCTTAAAACAGCACTTGCCGCCAGTGG GAGGAGGGAGGTTTTATTTATTCCCACAGTTTCTCCTGGGCCTTCTGGAATGACCATGTTTTCCTGTGGCGGTGGGTGTGTCATTGCGCC CGCCGTCTTCCAAAGCCTTACTTCCCCAAGCTGCCAGCCAGGAGGTGATAACCACCCTCCCAGAGTTTCTCTCGGCTCTTTTTTTAAAAG TCCCCCAACAAATAGGATTCTTGCTGGGAAAGGAAGTTCGGTAAGGAAATGTCAAATCTGGTTTTTAAACAAGGTCCAACCCTGCAATGA AGCAGCCACTTCAGCCCAGAGAGATTATAAGAACTGATGTGGCCAGAGTGCCTACCCACTGTGGCCCCGGTGCTCTGCCCCCACGCCCCG ACCATCTGGTCTTGGTAGATGTCCCTAGACGGGCTGAGCCATGTGCAATAAGAACATAGATCCTAAAGGATCCTCTGGAAGCTGTATTTC >53569_53569_10_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000401998_DNAJB12_chr10_74096454_ENST00000394903_length(amino acids)=324AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPTTG -------------------------------------------------------------- >53569_53569_11_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000401998_DNAJB12_chr10_74096454_ENST00000444643_length(transcript)=3116nt_BP=1004nt GTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCAC TTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGG CTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAA AAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAG AAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAA TCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAA CACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAAAATTTCCCAGGAACGAGAAA AATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTT CCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAA TTAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAG CCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATG TTCTGAAGCTTGAGGTCCGTGGGCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCTACTATGTGGGAGACACTTTCTCCGAA GAGTACACAGGCTCCAGCCTCAAAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACCTCCGGAACAACTGCTGGAAGGAGAAG CAGCAGAAGGAAGGCTTGCTGTACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAGCACAGAAGATGGGCACCCCCAGCTGC AGCCGACTGTCAGAGGTGCAGGCCTCCCTGCATGGATAGTCCTGGGCCAGCCACACCACCGAGGTCCAAACTATGAAATCCCTGGAGAAT TTTTGGTGACATGCACTGAGCCAAGGTGATGGACTGTATATTTGAGGAAAGACAAACAAAGAAACAAAATTAAAATGGAATTGGAGGCCG AACGCTGCACAGCTGCCCTCTCTCTCACCCAGTAAATGCAGAAAGCTCTTAGGACAGACAGAAAACCTGCCATGGGGCTGCTTCCCTCCC TCGCAGGGCTGGCGGAGGCTCCGCATCGCCTCTCTCCTAGGATACAGAAACCATGGCAACGAAAGTAGAATGTAAAACTCGCAGCAGATA TCAGTGGGAAGGGCTGGGGGAGGGGGCACCCAGCTGCCTTTCCTCCCTCACAGGAGCCACCACCAGCCACCTCTCAGGAGAAGCCAGAGG CCCTGGCCAAAGATAGGAGGAAGAAAGAGAACTCTCCATAGAATGTAATTTATAGATGCGTGTATATGTATATATATCTATTTATATGTA AATAGGCATATATGAAGATATATATATATATAGTCTACTTTTTAAACTCTGCAGGGATTTGGTTAAGTTGTTGAGCTGATTTCTTCCATG TTTTAGAAAATGAGGCCTGTTTGGGGAAGGTACCCTGGTGATGTTTTTGCTAGACATTAGCTGTAGCTGACAGCATAAGGAGAGTCGCAT CAGAGCTTTTCACAGCCCCCCGAAACCCCAGCCTGGTTTTGATGGCAGCAGTAATCATGATAGTGTGAACCCGCGAAGGCCTCAGGATTA TGGTTAACCTGGAGAGGAGCAGGCCATGGAGGCAGGTGCCAGGTCAGTATTGAGTCACAGTAGAGGCCCCACAAGGACCTGCTTGGGTGA GACCACCTCTCCCCTCTCAGCAGCGCTGGTGGGCTCTTTGTCCTGGTGCCCAGGAGCCCTCCAGCCCCCTGCCCACAGAAGGGAAGGCCT GCAGAGGGGGCCAGGATCTACCTAACCATTTCCCCACCCCTAAGTCCCTCAGTGGGCTTTGCCTTATAGGTGCCACAGGGCACAGCTCCA TCATTGCCACTGGTTTTTCCTAAGTCATGCACCAAGGACTTCAGAAAGTTCTTCCTCCGAGTCAGTCAGTGGTGCCGGGACCCCAGGGCA GCCTCCTCGACTCCTGAAGAAAAGGCAGTGCCCGTGGCTGCCTCTGTCTTCACTCGCTGTTGATGTGACCGCCAGGCCTCCTCTCGTACC TTGGACAAAGGATACACCTGAACCAGAATAGTTTTCTTACCCTCACATTGAAATGAGGATTTTGCTTAAAACAGCACTTGCCGCCAGTGG GAGGAGGGAGGTTTTATTTATTCCCACAGTTTCTCCTGGGCCTTCTGGAATGACCATGTTTTCCTGTGGCGGTGGGTGTGTCATTGCGCC CGCCGTCTTCCAAAGCCTTACTTCCCCAAGCTGCCAGCCAGGAGGTGATAACCACCCTCCCAGAGTTTCTCTCGGCTCTTTTTTTAAAAG TCCCCCAACAAATAGGATTCTTGCTGGGAAAGGAAGTTCGGTAAGGAAATGTCAAATCTGGTTTTTAAACAAGGTCCAACCCTGCAATGA AGCAGCCACTTCAGCCCAGAGAGATTATAAGAACTGATGTGGCCAGAGTGCCTACCCACTGTGGCCCCGGTGCTCTGCCCCCACGCCCCG ACCATCTGGTCTTGGTAGATGTCCCTAGACGGGCTGAGCCATGTGCAATAAGAACATAGATCCTAAAGGATCCTCTGGAAGCTGTATTTC >53569_53569_11_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000401998_DNAJB12_chr10_74096454_ENST00000444643_length(amino acids)=324AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPTTG -------------------------------------------------------------- >53569_53569_12_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000401998_DNAJB12_chr10_74096454_ENST00000461919_length(transcript)=1812nt_BP=1004nt GTTTCATCTCTATGGCTGTCAGAGGTGGGCGGCTTTGACCGAGAGGCTGCTGGAGCTCGTGTTTGGACGCGATGTTTCGTCTGAACTCAC TTTCTGCTTTGGCAGAACTGGCTGTGGGTTCTCGATGGTACCATGGAGGATCACAGCCCATCCAGATCCGGCGAAGACTAATGATGGTGG CTTTCCTGGGAGCATCTGCAGTAACTGCAAGTACTGGTCTTTTGTGGAAGAGGGCCCATGCAGAATCTCCACCATGTGTAGACAACCTAA AAAGTGACATCGGTGATAAAGGGAAGAATAAAGATGAAGGGGATGTTTGTAACCATGAGAAAAAGACTGCAGATCTTGCCCCTCACCCAG AAGAGAAAAAGAAGAAACGTTCTGGATTCAGAGACAGAAAAGTGATGGAATATGAGAATAGGATTCGAGCCTACTCCACGCCAGACAAAA TCTTCCGATATTTTGCCACCTTGAAAGTCATCAGTGAGCCTGGTGAAGCAGAAGTGTTTATGACACCAGAAGATTTTGTGCGATCCATAA CACCCAATGAAAAACAACCAGAACACTTGGGTCTGGATCAATATATAATAAAACGCTTTGATGGAAAGAAAATTTCCCAGGAACGAGAAA AATTTGCTGATGAAGGCAGTATATTTTACACCCTTGGAGAATGTGGGCTCATATCCTTTTCAGACTACATTTTCCTCACAACTGTTCTTT CCACTCCTCAGAGAAATTTTGAAATTGCCTTCAAGATGTTTGATTTGAATGGAGATGGAGAAGTAGATATGGAAGAATTTGAACAGGCAA TTAGCATCATTCGCTCCCAAACCAGTATGGGTATGCGCCACAGAGATCGTCCAACTACTGGCAACACCCTCAAGTCTGGCTTGTGTTCAG CCCTCACAACCTACTTTTTTGGAGCTGATCTGAAGGGAAAGCTGACAATCAAAAACTTCCTCGAATTTCAGCGTAAACTGCAGCATGATG TTCTGAAGCTTGAGGTCCGTGGGCCACATCCACAGGCGAGTCACTGACCACCTGGGTGTCGTCTACTATGTGGGAGACACTTTCTCCGAA GAGTACACAGGCTCCAGCCTCAAAACAGTCGAGCGGAATGTGGAAGATGATTATATCGCCAACCTCCGGAACAACTGCTGGAAGGAGAAG CAGCAGAAGGAAGGCTTGCTGTACCGGGCACGCTACTTTGGCGACACAGATATGTACCACAGAGCACAGAAGATGGGCACCCCCAGCTGC AGCCGACTGTCAGAGACTATGAAATCCCTGGAGAATTTTTGGTGACATGCACTGAGCCAAGGTGATGGACTGTATATTTGAGGAAAGACA AACAAAGAAACAAAATTAAAATGGAATTGGAGGCCGAACGCTGCACAGCTGCCCTCTCTCTCACCCAGTAAATGCAGAAAGCTCTTAGGA CAGACAGAAAACCTGCCATGGGGCTGCTTCCCTCCCTCGCAGGGCTGGCGGAGGCTCCGCATCGCCTCTCTCCTAGGATACAGAAACCAT GGCAACGAAAGTAGAATGTAAAACTCGCAGCAGATATCAGTGGGAAGGGCTGGGGGAGGGGGCACCCAGCTGCCTTTCCTCCCTCACAGG AGCCACCACCAGCCACCTCTCAGGAGAAGCCAGAGGCCCTGGCCAAAGATAGGAGGAAGAAAGAGAACTCTCCATAGAATGTAATTTATA GATGCGTGTATATGTATATATATCTATTTATATGTAAATAGGCATATATGAAGATATATATATATATAGTCTACTTTTTAAACTCTGCAG >53569_53569_12_MICU1-DNAJB12_MICU1_chr10_74234858_ENST00000401998_DNAJB12_chr10_74096454_ENST00000461919_length(amino acids)=324AA_BP=3 MDAMFRLNSLSALAELAVGSRWYHGGSQPIQIRRRLMMVAFLGASAVTASTGLLWKRAHAESPPCVDNLKSDIGDKGKNKDEGDVCNHEK KTADLAPHPEEKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVISEPGEAEVFMTPEDFVRSITPNEKQPEHLGLDQYIIKRFD GKKISQEREKFADEGSIFYTLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQAISIIRSQTSMGMRHRDRPTTG -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for MICU1-DNAJB12 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for MICU1-DNAJB12 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for MICU1-DNAJB12 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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