Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:MIPEP-GATAD2A (FusionGDB2 ID:53743)

Fusion Gene Summary for MIPEP-GATAD2A

Fusion gene summary

Fusion gene information	Fusion gene name: MIPEP-GATAD2A
	Fusion gene ID: 53743
		Hgene	Tgene
	Gene symbol	MIPEP	GATAD2A
	Gene ID	4285	54815
	Gene name	mitochondrial intermediate peptidase	GATA zinc finger domain containing 2A
	Synonyms	COXPD31\|HMIP\|MIP	p66alpha
	Cytomap	13q12.12	19p13.11
	Type of gene	protein-coding	protein-coding
	Description	mitochondrial intermediate peptidase	transcriptional repressor p66-alphaGATA zinc finger domain-containing protein 2A
	Modification date	20200313	20200313
	UniProtAcc	Q99797	Q86YP4
	Ensembl transtripts involved in fusion gene	ENST00000382172, ENST00000469167,	ENST00000473184, ENST00000358713, ENST00000404158, ENST00000429563, ENST00000537887, ENST00000252577, ENST00000360315,
Fusion gene scores	* DoF score	7 X 7 X 6=294	11 X 10 X 9=990
	# samples	7	14
	** MAII score	log2(7/294*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(14/990*10)=-2.82200169802201 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: MIPEP [Title/Abstract] AND GATAD2A [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	MIPEP(24432999)-GATAD2A(19603115), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	GATAD2A	GO:0045892	negative regulation of transcription, DNA-templated	12183469

Fusion gene breakpoints across MIPEP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across GATAD2A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LGG	TCGA-TM-A84B-01A	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+

Top

Fusion Gene ORF analysis for MIPEP-GATAD2A

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-3UTR	ENST00000382172	ENST00000473184	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
5CDS-intron	ENST00000382172	ENST00000358713	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
5CDS-intron	ENST00000382172	ENST00000404158	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
5CDS-intron	ENST00000382172	ENST00000429563	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
5CDS-intron	ENST00000382172	ENST00000537887	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
In-frame	ENST00000382172	ENST00000252577	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
In-frame	ENST00000382172	ENST00000360315	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
intron-3CDS	ENST00000469167	ENST00000252577	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
intron-3CDS	ENST00000469167	ENST00000360315	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
intron-3UTR	ENST00000469167	ENST00000473184	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
intron-intron	ENST00000469167	ENST00000358713	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
intron-intron	ENST00000469167	ENST00000404158	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
intron-intron	ENST00000469167	ENST00000429563	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+
intron-intron	ENST00000469167	ENST00000537887	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

ENST00000382172

MIPEP

chr13

24432999

ENST00000252577

GATAD2A

chr19

19603115

6220

1205

2762

917

ENST00000382172

MIPEP

chr13

24432999

ENST00000360315

GATAD2A

chr19

19603115

6295

1205

2837

942

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000382172	ENST00000252577	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+	0.003047767	0.9969522
ENST00000382172	ENST00000360315	MIPEP	chr13	24432999	-	GATAD2A	chr19	19603115	+	0.00237429	0.99762577

Top

Fusion Genomic Features for MIPEP-GATAD2A

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for MIPEP-GATAD2A

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:24432999/chr19:19603115)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
MIPEP Q99797	GATAD2A Q86YP4
FUNCTION: Cleaves proteins, imported into the mitochondrion, to their mature size.	FUNCTION: Transcriptional repressor. Enhances MBD2-mediated repression. Efficient repression requires the presence of GATAD2B. {ECO:0000269\|PubMed:12183469, ECO:0000269\|PubMed:16415179}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000252577

139_174

609.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000358713

139_174

634.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000360315

139_174

634.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000404158

139_174

635.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000252577

340_480

609.0

Region

CR2%3B histone tail-binding

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000358713

340_480

634.0

Region

CR2%3B histone tail-binding

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000360315

340_480

634.0

Region

CR2%3B histone tail-binding

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000404158

340_480

635.0

Region

CR2%3B histone tail-binding

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000252577

411_464

609.0

Zinc finger

GATA-type

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000358713

411_464

634.0

Zinc finger

GATA-type

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000360315

411_464

634.0

Zinc finger

GATA-type

Tgene

GATAD2A

chr13:24432999

chr19:19603115

ENST00000404158

411_464

635.0

Zinc finger

GATA-type

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Top

Fusion Gene Sequence for MIPEP-GATAD2A

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>53743_53743_1_MIPEP-GATAD2A_MIPEP_chr13_24432999_ENST00000382172_GATAD2A_chr19_19603115_ENST00000252577_length(transcript)=6220nt_BP=1205nt
CGGCGTGGGCTGCTGCCTTGGAAACGCGGAGCGCGCGCTCCCAGCGAAAGCAGCAGGGCAGGGATCTGCGTTGGAGGAAGGGACTGCTCT
GGTGCTAGAATGCTGTGCGTCGGAAGGCTGGGCGGCTTGGGAGCCAGAGCAGCAGCTCTGCCGCCCCGCCGGGCGGGCCGGGGAAGCCTC
GAAGCCGGGATCCGGGCCCGAAGGGTCAGCACCAGCTGGTCTCCCGTGGGCGCCGCCTTCAATGTCAAGCCCCAGGGCAGCCGCTTGGAC
CTGTTCGGCGAGCGCCGGGGTCTTTTTGGAGTTCCTGAGCTGAGTGCCCCAGAAGGATTTCATATTGCACAAGAAAAAGCCTTGAGAAAG
ACAGAATTGCTTGTGGACCGTGCATGTTCCACCCCACCTGGGCCCCAGACCGTGCTGATCTTCGATGAGCTCTCGGATTCCTTATGCAGA
GTGGCCGACTTGGCTGATTTTGTGAAAATCGCTCACCCTGAGCCAGCATTCAGAGAAGCTGCGGAAGAAGCTTGTAGAAGTATTGGCACC
ATGGTAGAGAAGTTGAACACAAATGTGGATTTATATCAAAGTTTGCAAAAATTACTAGCTGATAAAAAACTTGTGGATTCCCTTGATCCA
GAAACAAGGCGAGTGGCTGAACTGTTTATGTTTGATTTTGAAATTAGTGGAATCCATCTAGACAAAGAAAAGCGTAAAAGAGCAGTGGAC
CTCAATGTTAAAATCTTGGATTTGAGTAGTACATTTCTTATGGGAACCAATTTTCCCAACAAGATTGAGAAGCATCTCTTACCAGAACAC
ATTCGTCGTAACTTTACATCTGCTGGGGATCATATCATAATTGATGGTCTCCACGCAGAATCACCAGATGACTTGGTGCGAGAAGCTGCT
TATAAAATTTTTCTTTATCCCAATGCTGGTCAATTGAAATGTTTAGAAGAATTGCTCAGCAGCAGAGATCTTCTGGCAAAGTTGGTGGGG
TATTCCACGTTTTCTCACAGGGCTCTCCAAGGAACGATAGCTAAAAATCCAGAGACTGTCATGCAGTTCCTTGAAAAACTATCTGACAAA
CTTTCTGAAAGAACTCTGAAAGATTTTGAGATGATACGAGGGATGAAAATGAAACTGAATCCTCAAAATTCCGAAGTAATGCCCTGGGAC
CCCCCTTACTACAGTGGTGTGATTCGTGCAGAAAGTGACATGAAGTCCGAGAGGAGACCCCCCTCACCTGACGTGATTGTGCTCTCCGAC
AACGAGCAGCCCTCGAGCCCGAGAGTGAATGGGCTGACCACGGTGGCCTTGAAGGAGACTAGCACCGAGGCCCTCATGAAAAGCAGTCCT
GAAGAACGAGAAAGGATGATCAAGCAGCTGAAGGAAGAATTGAGGTTAGAAGAAGCAAAACTCGTGTTGTTGAAAAAGTTGCGGCAGAGT
CAAATACAAAAGGAAGCCACCGCCCAGAAGCCCACAGGTTCTGTTGGGAGCACCGTGACCACCCCTCCCCCGCTTGTTCGGGGCACTCAG
AACATTCCTGCTGGCAAGCCATCACTCCAGACCTCTTCAGCTCGGATGCCCGGCAGTGTCATACCCCCGCCCCTGGTCCGAGGTGGGCAG
CAGGCGTCCTCGAAGCTGGGGCCACAGGCGAGCTCACAGGTCGTCATGCCCCCACTCGTCAGGGGGGCTCAGCAAATCCACAGCATTAGG
CAACATTCCAGCACAGGGCCACCGCCCCTCCTCCTGGCCCCCCGGGCGTCGGTGCCCAGTGTGCAGATTCAGGGACAGAGGATCATCCAG
CAGGGCCTCATCCGCGTCGCCAATGTTCCCAACACCAGCCTGCTCGTCAACATCCCACAGCCCACCCCAGCATCACTGAAGGGGACAACA
GCCACCTCCGCTCAGGCCAACTCCACCCCCACTAGTGTGGCCTCTGTGGTCACCTCTGCCGAGTCTCCAGCAAGCCGACAGGCGGCCGCC
AAGCTGGCGCTGCGCAAACAGCTGGAGAAGACGCTACTCGAGATCCCCCCACCCAAGCCCCCAGCCCCAGAGATGAACTTCCTGCCCAGC
GCCGCCAACAACGAGTTCATCTACCTGGTCGGCCTGGAGGAGGTGGTGCAGAACCTACTGGAGACACAAGGCAGGATGTCGGCCGCCACT
GTGCTGTCCCGGGAGCCCTACATGTGTGCACAGTGCAAGACGGACTTCACGTGCCGCTGGCGGGAGGAGAAGAGCGGCGCCATCATGTGT
GAGAACTGCATGACAACCAACCAGAAGAAGGCGCTCAAGGTGGAGCACACCAGCCGGCTGAAGGCCGCCTTTGTGAAGGCGCTGCAGCAG
GAACAGGAGATTGAGCAGCGGCTCCTGCAGCAGGGCACGGCCCCTGCACAGGCCAAGGCCGAGCCCACCGCTGCCCCACACCCCGTGCTG
AAGCAGGCCTCCAGCCAGCTGTCCCGGGGTTCGGCCACGACGCCCCGAGGTGTCCTGCACACGTTCAGTCCGTCACCCAAACTGCAGAAC
TCAGCCTCGGCCACAGCCCTGGTCAGCAGGACCGGCAGACATTCTGAGAGAACCGTGAGCGCCGGCAAGGGCAGCGCCACCTCCAACTGG
AAGAAGACGCCCCTCAGCACAGGCGGGACCCTTGCGTTTGTCAGCCCAAGCCTGGCGGTGCACAAGAGCTCCTCGGCCGTGGACCGCCAG
CGAGAGTACCTCCTGGACATGATCCCACCCCGCTCCATCCCCCAGTCAGCCACGTGGAAATAGTGCGAGCCAGGCCCCGTGGAAGACGGG
CTCCCTCCTCCCCCACCTGGCCCCTGGTCTAGAAGGACCCACTGCACCACCCTCCGCTGGCTCGGGAAGACACCGTGCCCGCCCCAAGAG
CAAGCACCGGCCATGCTGCAGAGGCAAGACCTCAATTCTTGGCTGCAAAGTTTCATCAGGGCTAGGGGGCTGGTGCCGCCTCATAGGCAG
ACGAGGATCATCGCTGGGGGACCTTTCCCGTGGGCTTTCTTCCTTTCTCTCTTTGCCTTTAGTTTGCCCGACACCAGCAGAAAAGTGGAC
CTTGGGGGCTGGTTCTGCTCCTGGCCCCCTTGTTCAGCCCCTGCCGGCACACGGGCGGCTCACCCTGGACACTGTGATGCGCATGGGCAA
GGCCAGCGCCCGGGGCTTCTGAACCGAGCGGGGTGTTTCATTTTTTTGCTTTTCCCTGTCTTAGGCTCCCAGTCTTTGACTGCCTTCCCA
TGGCGATCTATAAGTTGAAAGATTTTTTTTTTTTTTAATCACCTCATGATGATGGAGTTAAAAGTAAACCGTGCAGACCCTGGGGTCCCT
GTTGTACGCTGCATCATCCCGCTGGCCCTGTGCCCTGGAGGGTGGGCGGCTCATGGTGCCACAGCCCCTGGCAGGGACGGCCGGCCCGCC
CCCGTGACTGACTGACAGATGCAGGGATGGCCGAGGCAGCCCTCGCTCCAGCTGAACGCCTCCATTGCTGCTTGTTCTGGAGACCCCCGC
CCCCGCACCTTCCAGACTTAGCAGAAGAACAAACTGAAGAACAGACCCAGCCAGAGAAGCAGGGATTCCAGAAGCTGCCCATTAAGGGAG
AAGGAGAGGATCCGGTCGGCAGCAGCCCTGAGCAGAAAGCTGGAGGGGGGACTGTCGCGGGGTTTTTCTGTTGTGGTTTATTTTATTAAA
TTTTTTCCTTTTTTCTATTCATTTCGATGGACGCAATCTTAAGCCACCCTGGCCTTGCTCCTGGGAGGTGAGCGTGCACAGGTGTGTGCA
GGTCAGGAGGTGCCGTCCAGGTGTGCGGCGAGCCGCTGCGCACAGATGTCAGGATTTCCGTTTGGGTCTAGTTTAGAACCTGTCCTTAAA
CCTAGGGGTTGCTGTCAGGATTTGCTTTCAGACTTTTTTTTTTTTTGTAATTCCCTTTAGAGTCTACAAAAATGTTTTTAAAAGGATCAG
GTCTGCTTTTAGTTTCATTTTTGTTTCTTTCCCGTCCCACTCTTTAAAAACTGGTTCCGTGAGGAAAGGCAGAAGCCGTTCCGTGTCTCT
TGCAGGCTGGGCCGGCTTCATGCCAGTGCGAGGGCGTCCCGTGCCCACGTACATACGTATGTCTCCATGAGTTCTGGGCTCCACTGGTTC
CAATTGAGCTCCAGCCCTGGTTTTCCTACCCATGCAGTTAGGGACTTTAATTTAATTTTTTTTTTGTAGGGCCACCGCCTTCAAACACAA
CTGCTACAACATTCTAATAAAGGCTCATTTAACCCCCAGGCTCCTGTCGTGTGAATATCCTCAGTCTGTAGGAAACTTTTTTTGACACAG
CATAGAAGACCTAGTTTTGGAAAACATTATCTAATTTTTTGTTGTGCAAATCCCCAAATTTCTCACTAATTTTTGTTTTTTTGTGCATAA
CTTGGATGGGCTGAAGGAGGTGAGGACAGATTGGGGAAGGGTGGCTTTCATTCCAAGATCCAGGGATTTGGGGAAAAGGAAGGAATTTGA
TGTTTTTTGGGGTGGGAGGGGAGGGTGTGTTTTTTACACCAAAAAAAAAAAAAAAAATCAAGAGTATGCAAGCATTTCTATTCCTCGCAT
TTTTCTGTGTGCCTGGCAAATAAATACCTGTCTCCTACGACCCTGAGCTGTTAGCCCTCTCTGTTCCATGACAGGGGCCAGATCTTCCAG
CTCCTCCCAGAAGGAGCACCCAGGCTGGCTTCTTCCCACTGAAAGCCCTCCCCAGCGAACCAACCTCAGTTCTATGCAGTGGCTGGGGAT
CAGGCATCCAGACCGAAGTCACCTCTGCCTGCTCCAGCTTGGGTCAGCTGGGTCTGACCAGGGGGCCAGATCCGAGCCGCACCTGCCGGC
CCCCAGCCCCAGCTCCAGCTCCTGACCTCTCCCAGCCTGGCCTGGCTGTTCCTCCAGGGCTGATGGCTGTCAACCCATCCTTGTGAGTTC
ATATGGACTGCTGCCCCTCGAAAGGGAGAGGGTCGGCCCCATGTCCCCAGGGAGCATTCCATCAGGGACAACGTACATACTGTGATGTAA
ACTTTTTTTTTTTCCCCCCAGGGGGCAAAAGTGTGAGATGCCTTAATCTTTCCTTCATTTCTGCTGTCTCGAACACTCTAGCCCATTATT
TCCTTTCAGTTCCTTGCAGCATAACCTCTACGATAAGCCCCAAGCGGGTTGTTGTATTATGACGTTTATGATGTTCCAGGTGAAGGCATT
ATTAAGTACCTCTCTGGGTGTGGGGTTTGGACGCACCAGGATAGCTATTGATTAATGTTAAGGGTGTTCTACCCACAGCAAAGCACACCC
TCTTAAACCAGGCACTGCCTGGGTCCTGGTCCCGAGAGCCCTACCAGGATCAGGTTCCTGCAAGCCGTCAGAATGTGGGAGCCCCCAGCC
CAACTGATTGTAACTGTCCCCTGTTACCTGTGACATGAACCTCCAACAGCACCTGGAAACGGTTCCCTCTGTCAGCTGCTCTGTAGACAG
GGCTGGGGAGATCTCAGAGTTCACACCTCGCCTGTTGTAGGGGAGGTTGGGGGTAGGGTTTGGAATGGCCAAGTGCCCTTGGAACCTCCC
ACAGCTATGGCCGTCCTGACCTCATCCCAGGAACTCTACGGTGACCAGGAACCACCCCTCTGACGAGGTCTGTAGCGGCCCTTCTCAGAG
TGGAACAGCCCACAGTGCTAGTTGTGCCTGGTCTTACCTGTACTCCACGGACCTCGGTGAAGCAAAAGCTTCAGGGCAGAGGGAATGAGG
CAACCCAGTGGCAGCCCCGCTGGGCCCCGTGGCTCCTGCTCTCCTATTGGACGTAGAGGCAGGGGAGAGACTTCTCTATACAAATATTCT
CATCACAGAAGGGATGATCCTTGCTGCTCTGCCGTAGGGTTTTTGATGCTGAGCTATGCTGCACATGACGTTAACCTAAAGAACTTGGAC
TGAGCTTTTAAAAAAGGACAGCAAACAATTTTATAATCCTTAAAGTGTAATAGACGGTTACACTAGTGCAGGGTATTGGGGAGGCTCTTT
GGGTGTGGAGGCTGTCACTTGTATTTATTGTGACTCTAAATCTTTGATAGTAAAACAAATGTAAAAAGAAATGTTTGCCACCAGATGGGA
ATAGAAGTTCCAATAAGCAGGCTGGAATGGGTGGCTATACGTTGTATCACGAGGAAGTTTTAGACTCTGAAGGATAATAAATGGATGATG

>53743_53743_1_MIPEP-GATAD2A_MIPEP_chr13_24432999_ENST00000382172_GATAD2A_chr19_19603115_ENST00000252577_length(amino acids)=917AA_BP=398
MLPWKRGARAPSESSRAGICVGGRDCSGARMLCVGRLGGLGARAAALPPRRAGRGSLEAGIRARRVSTSWSPVGAAFNVKPQGSRLDLFG
ERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRACSTPPGPQTVLIFDELSDSLCRVADLADFVKIAHPEPAFREAAEEACRSIGTMVE
KLNTNVDLYQSLQKLLADKKLVDSLDPETRRVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPNKIEKHLLPEHIRR
NFTSAGDHIIIDGLHAESPDDLVREAAYKIFLYPNAGQLKCLEELLSSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEKLSDKLSE
RTLKDFEMIRGMKMKLNPQNSEVMPWDPPYYSGVIRAESDMKSERRPPSPDVIVLSDNEQPSSPRVNGLTTVALKETSTEALMKSSPEER
ERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQAS
SKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVNIPQPTPASLKGTTATS
AQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMSAATVLS
REPYMCAQCKTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQA
SSQLSRGSATTPRGVLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTGGTLAFVSPSLAVHKSSSAVDRQREY

--------------------------------------------------------------
>53743_53743_2_MIPEP-GATAD2A_MIPEP_chr13_24432999_ENST00000382172_GATAD2A_chr19_19603115_ENST00000360315_length(transcript)=6295nt_BP=1205nt
CGGCGTGGGCTGCTGCCTTGGAAACGCGGAGCGCGCGCTCCCAGCGAAAGCAGCAGGGCAGGGATCTGCGTTGGAGGAAGGGACTGCTCT
GGTGCTAGAATGCTGTGCGTCGGAAGGCTGGGCGGCTTGGGAGCCAGAGCAGCAGCTCTGCCGCCCCGCCGGGCGGGCCGGGGAAGCCTC
GAAGCCGGGATCCGGGCCCGAAGGGTCAGCACCAGCTGGTCTCCCGTGGGCGCCGCCTTCAATGTCAAGCCCCAGGGCAGCCGCTTGGAC
CTGTTCGGCGAGCGCCGGGGTCTTTTTGGAGTTCCTGAGCTGAGTGCCCCAGAAGGATTTCATATTGCACAAGAAAAAGCCTTGAGAAAG
ACAGAATTGCTTGTGGACCGTGCATGTTCCACCCCACCTGGGCCCCAGACCGTGCTGATCTTCGATGAGCTCTCGGATTCCTTATGCAGA
GTGGCCGACTTGGCTGATTTTGTGAAAATCGCTCACCCTGAGCCAGCATTCAGAGAAGCTGCGGAAGAAGCTTGTAGAAGTATTGGCACC
ATGGTAGAGAAGTTGAACACAAATGTGGATTTATATCAAAGTTTGCAAAAATTACTAGCTGATAAAAAACTTGTGGATTCCCTTGATCCA
GAAACAAGGCGAGTGGCTGAACTGTTTATGTTTGATTTTGAAATTAGTGGAATCCATCTAGACAAAGAAAAGCGTAAAAGAGCAGTGGAC
CTCAATGTTAAAATCTTGGATTTGAGTAGTACATTTCTTATGGGAACCAATTTTCCCAACAAGATTGAGAAGCATCTCTTACCAGAACAC
ATTCGTCGTAACTTTACATCTGCTGGGGATCATATCATAATTGATGGTCTCCACGCAGAATCACCAGATGACTTGGTGCGAGAAGCTGCT
TATAAAATTTTTCTTTATCCCAATGCTGGTCAATTGAAATGTTTAGAAGAATTGCTCAGCAGCAGAGATCTTCTGGCAAAGTTGGTGGGG
TATTCCACGTTTTCTCACAGGGCTCTCCAAGGAACGATAGCTAAAAATCCAGAGACTGTCATGCAGTTCCTTGAAAAACTATCTGACAAA
CTTTCTGAAAGAACTCTGAAAGATTTTGAGATGATACGAGGGATGAAAATGAAACTGAATCCTCAAAATTCCGAAGTAATGCCCTGGGAC
CCCCCTTACTACAGTGGTGTGATTCGTGCAGAAAGTGACATGAAGTCCGAGAGGAGACCCCCCTCACCTGACGTGATTGTGCTCTCCGAC
AACGAGCAGCCCTCGAGCCCGAGAGTGAATGGGCTGACCACGGTGGCCTTGAAGGAGACTAGCACCGAGGCCCTCATGAAAAGCAGTCCT
GAAGAACGAGAAAGGATGATCAAGCAGCTGAAGGAAGAATTGAGGTTAGAAGAAGCAAAACTCGTGTTGTTGAAAAAGTTGCGGCAGAGT
CAAATACAAAAGGAAGCCACCGCCCAGAAGCCCACAGGTTCTGTTGGGAGCACCGTGACCACCCCTCCCCCGCTTGTTCGGGGCACTCAG
AACATTCCTGCTGGCAAGCCATCACTCCAGACCTCTTCAGCTCGGATGCCCGGCAGTGTCATACCCCCGCCCCTGGTCCGAGGTGGGCAG
CAGGCGTCCTCGAAGCTGGGGCCACAGGCGAGCTCACAGGTCGTCATGCCCCCACTCGTCAGGGGGGCTCAGCAAATCCACAGCATTAGG
CAACATTCCAGCACAGGGCCACCGCCCCTCCTCCTGGCCCCCCGGGCGTCGGTGCCCAGTGTGCAGATTCAGGGACAGAGGATCATCCAG
CAGGGCCTCATCCGCGTCGCCAATGTTCCCAACACCAGCCTGCTCGTCAACATCCCACAGCCCACCCCAGCATCACTGAAGGGGACAACA
GCCACCTCCGCTCAGGCCAACTCCACCCCCACTAGTGTGGCCTCTGTGGTCACCTCTGCCGAGTCTCCAGCAAGCCGACAGGCGGCCGCC
AAGCTGGCGCTGCGCAAACAGCTGGAGAAGACGCTACTCGAGATCCCCCCACCCAAGCCCCCAGCCCCAGAGATGAACTTCCTGCCCAGC
GCCGCCAACAACGAGTTCATCTACCTGGTCGGCCTGGAGGAGGTGGTGCAGAACCTACTGGAGACACAAGGCAGGATGTCGGCCGCCACT
GTGCTGTCCCGGGAGCCCTACATGTGTGCACAGTGCAAGACGGACTTCACGTGCCGCTGGCGGGAGGAGAAGAGCGGCGCCATCATGTGT
GAGAACTGCATGACAACCAACCAGAAGAAGGCGCTCAAGGTGGAGCACACCAGCCGGCTGAAGGCCGCCTTTGTGAAGGCGCTGCAGCAG
GAACAGGAGATTGAGCAGCGGCTCCTGCAGCAGGGCACGGCCCCTGCACAGGCCAAGGCCGAGCCCACCGCTGCCCCACACCCCGTGCTG
AAGCAGGTCATAAAACCCCGGCGTAAGTTGGCGTTCCGCTCAGGAGAGGCCCGCGACTGGAGTAACGGGGCTGTGCTACAGGCCTCCAGC
CAGCTGTCCCGGGGTTCGGCCACGACGCCCCGAGGTGTCCTGCACACGTTCAGTCCGTCACCCAAACTGCAGAACTCAGCCTCGGCCACA
GCCCTGGTCAGCAGGACCGGCAGACATTCTGAGAGAACCGTGAGCGCCGGCAAGGGCAGCGCCACCTCCAACTGGAAGAAGACGCCCCTC
AGCACAGGCGGGACCCTTGCGTTTGTCAGCCCAAGCCTGGCGGTGCACAAGAGCTCCTCGGCCGTGGACCGCCAGCGAGAGTACCTCCTG
GACATGATCCCACCCCGCTCCATCCCCCAGTCAGCCACGTGGAAATAGTGCGAGCCAGGCCCCGTGGAAGACGGGCTCCCTCCTCCCCCA
CCTGGCCCCTGGTCTAGAAGGACCCACTGCACCACCCTCCGCTGGCTCGGGAAGACACCGTGCCCGCCCCAAGAGCAAGCACCGGCCATG
CTGCAGAGGCAAGACCTCAATTCTTGGCTGCAAAGTTTCATCAGGGCTAGGGGGCTGGTGCCGCCTCATAGGCAGACGAGGATCATCGCT
GGGGGACCTTTCCCGTGGGCTTTCTTCCTTTCTCTCTTTGCCTTTAGTTTGCCCGACACCAGCAGAAAAGTGGACCTTGGGGGCTGGTTC
TGCTCCTGGCCCCCTTGTTCAGCCCCTGCCGGCACACGGGCGGCTCACCCTGGACACTGTGATGCGCATGGGCAAGGCCAGCGCCCGGGG
CTTCTGAACCGAGCGGGGTGTTTCATTTTTTTGCTTTTCCCTGTCTTAGGCTCCCAGTCTTTGACTGCCTTCCCATGGCGATCTATAAGT
TGAAAGATTTTTTTTTTTTTTAATCACCTCATGATGATGGAGTTAAAAGTAAACCGTGCAGACCCTGGGGTCCCTGTTGTACGCTGCATC
ATCCCGCTGGCCCTGTGCCCTGGAGGGTGGGCGGCTCATGGTGCCACAGCCCCTGGCAGGGACGGCCGGCCCGCCCCCGTGACTGACTGA
CAGATGCAGGGATGGCCGAGGCAGCCCTCGCTCCAGCTGAACGCCTCCATTGCTGCTTGTTCTGGAGACCCCCGCCCCCGCACCTTCCAG
ACTTAGCAGAAGAACAAACTGAAGAACAGACCCAGCCAGAGAAGCAGGGATTCCAGAAGCTGCCCATTAAGGGAGAAGGAGAGGATCCGG
TCGGCAGCAGCCCTGAGCAGAAAGCTGGAGGGGGGACTGTCGCGGGGTTTTTCTGTTGTGGTTTATTTTATTAAATTTTTTCCTTTTTTC
TATTCATTTCGATGGACGCAATCTTAAGCCACCCTGGCCTTGCTCCTGGGAGGTGAGCGTGCACAGGTGTGTGCAGGTCAGGAGGTGCCG
TCCAGGTGTGCGGCGAGCCGCTGCGCACAGATGTCAGGATTTCCGTTTGGGTCTAGTTTAGAACCTGTCCTTAAACCTAGGGGTTGCTGT
CAGGATTTGCTTTCAGACTTTTTTTTTTTTTGTAATTCCCTTTAGAGTCTACAAAAATGTTTTTAAAAGGATCAGGTCTGCTTTTAGTTT
CATTTTTGTTTCTTTCCCGTCCCACTCTTTAAAAACTGGTTCCGTGAGGAAAGGCAGAAGCCGTTCCGTGTCTCTTGCAGGCTGGGCCGG
CTTCATGCCAGTGCGAGGGCGTCCCGTGCCCACGTACATACGTATGTCTCCATGAGTTCTGGGCTCCACTGGTTCCAATTGAGCTCCAGC
CCTGGTTTTCCTACCCATGCAGTTAGGGACTTTAATTTAATTTTTTTTTTGTAGGGCCACCGCCTTCAAACACAACTGCTACAACATTCT
AATAAAGGCTCATTTAACCCCCAGGCTCCTGTCGTGTGAATATCCTCAGTCTGTAGGAAACTTTTTTTGACACAGCATAGAAGACCTAGT
TTTGGAAAACATTATCTAATTTTTTGTTGTGCAAATCCCCAAATTTCTCACTAATTTTTGTTTTTTTGTGCATAACTTGGATGGGCTGAA
GGAGGTGAGGACAGATTGGGGAAGGGTGGCTTTCATTCCAAGATCCAGGGATTTGGGGAAAAGGAAGGAATTTGATGTTTTTTGGGGTGG
GAGGGGAGGGTGTGTTTTTTACACCAAAAAAAAAAAAAAAAATCAAGAGTATGCAAGCATTTCTATTCCTCGCATTTTTCTGTGTGCCTG
GCAAATAAATACCTGTCTCCTACGACCCTGAGCTGTTAGCCCTCTCTGTTCCATGACAGGGGCCAGATCTTCCAGCTCCTCCCAGAAGGA
GCACCCAGGCTGGCTTCTTCCCACTGAAAGCCCTCCCCAGCGAACCAACCTCAGTTCTATGCAGTGGCTGGGGATCAGGCATCCAGACCG
AAGTCACCTCTGCCTGCTCCAGCTTGGGTCAGCTGGGTCTGACCAGGGGGCCAGATCCGAGCCGCACCTGCCGGCCCCCAGCCCCAGCTC
CAGCTCCTGACCTCTCCCAGCCTGGCCTGGCTGTTCCTCCAGGGCTGATGGCTGTCAACCCATCCTTGTGAGTTCATATGGACTGCTGCC
CCTCGAAAGGGAGAGGGTCGGCCCCATGTCCCCAGGGAGCATTCCATCAGGGACAACGTACATACTGTGATGTAAACTTTTTTTTTTTCC
CCCCAGGGGGCAAAAGTGTGAGATGCCTTAATCTTTCCTTCATTTCTGCTGTCTCGAACACTCTAGCCCATTATTTCCTTTCAGTTCCTT
GCAGCATAACCTCTACGATAAGCCCCAAGCGGGTTGTTGTATTATGACGTTTATGATGTTCCAGGTGAAGGCATTATTAAGTACCTCTCT
GGGTGTGGGGTTTGGACGCACCAGGATAGCTATTGATTAATGTTAAGGGTGTTCTACCCACAGCAAAGCACACCCTCTTAAACCAGGCAC
TGCCTGGGTCCTGGTCCCGAGAGCCCTACCAGGATCAGGTTCCTGCAAGCCGTCAGAATGTGGGAGCCCCCAGCCCAACTGATTGTAACT
GTCCCCTGTTACCTGTGACATGAACCTCCAACAGCACCTGGAAACGGTTCCCTCTGTCAGCTGCTCTGTAGACAGGGCTGGGGAGATCTC
AGAGTTCACACCTCGCCTGTTGTAGGGGAGGTTGGGGGTAGGGTTTGGAATGGCCAAGTGCCCTTGGAACCTCCCACAGCTATGGCCGTC
CTGACCTCATCCCAGGAACTCTACGGTGACCAGGAACCACCCCTCTGACGAGGTCTGTAGCGGCCCTTCTCAGAGTGGAACAGCCCACAG
TGCTAGTTGTGCCTGGTCTTACCTGTACTCCACGGACCTCGGTGAAGCAAAAGCTTCAGGGCAGAGGGAATGAGGCAACCCAGTGGCAGC
CCCGCTGGGCCCCGTGGCTCCTGCTCTCCTATTGGACGTAGAGGCAGGGGAGAGACTTCTCTATACAAATATTCTCATCACAGAAGGGAT
GATCCTTGCTGCTCTGCCGTAGGGTTTTTGATGCTGAGCTATGCTGCACATGACGTTAACCTAAAGAACTTGGACTGAGCTTTTAAAAAA
GGACAGCAAACAATTTTATAATCCTTAAAGTGTAATAGACGGTTACACTAGTGCAGGGTATTGGGGAGGCTCTTTGGGTGTGGAGGCTGT
CACTTGTATTTATTGTGACTCTAAATCTTTGATAGTAAAACAAATGTAAAAAGAAATGTTTGCCACCAGATGGGAATAGAAGTTCCAATA

>53743_53743_2_MIPEP-GATAD2A_MIPEP_chr13_24432999_ENST00000382172_GATAD2A_chr19_19603115_ENST00000360315_length(amino acids)=942AA_BP=398
MLPWKRGARAPSESSRAGICVGGRDCSGARMLCVGRLGGLGARAAALPPRRAGRGSLEAGIRARRVSTSWSPVGAAFNVKPQGSRLDLFG
ERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRACSTPPGPQTVLIFDELSDSLCRVADLADFVKIAHPEPAFREAAEEACRSIGTMVE
KLNTNVDLYQSLQKLLADKKLVDSLDPETRRVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPNKIEKHLLPEHIRR
NFTSAGDHIIIDGLHAESPDDLVREAAYKIFLYPNAGQLKCLEELLSSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEKLSDKLSE
RTLKDFEMIRGMKMKLNPQNSEVMPWDPPYYSGVIRAESDMKSERRPPSPDVIVLSDNEQPSSPRVNGLTTVALKETSTEALMKSSPEER
ERMIKQLKEELRLEEAKLVLLKKLRQSQIQKEATAQKPTGSVGSTVTTPPPLVRGTQNIPAGKPSLQTSSARMPGSVIPPPLVRGGQQAS
SKLGPQASSQVVMPPLVRGAQQIHSIRQHSSTGPPPLLLAPRASVPSVQIQGQRIIQQGLIRVANVPNTSLLVNIPQPTPASLKGTTATS
AQANSTPTSVASVVTSAESPASRQAAAKLALRKQLEKTLLEIPPPKPPAPEMNFLPSAANNEFIYLVGLEEVVQNLLETQGRMSAATVLS
REPYMCAQCKTDFTCRWREEKSGAIMCENCMTTNQKKALKVEHTSRLKAAFVKALQQEQEIEQRLLQQGTAPAQAKAEPTAAPHPVLKQV
IKPRRKLAFRSGEARDWSNGAVLQASSQLSRGSATTPRGVLHTFSPSPKLQNSASATALVSRTGRHSERTVSAGKGSATSNWKKTPLSTG

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for MIPEP-GATAD2A

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for MIPEP-GATAD2A

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for MIPEP-GATAD2A

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source