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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MIPEP-MYO16 (FusionGDB2 ID:53744)

Fusion Gene Summary for MIPEP-MYO16

check button Fusion gene summary
Fusion gene informationFusion gene name: MIPEP-MYO16
Fusion gene ID: 53744
HgeneTgene
Gene symbol

MIPEP

MYO16

Gene ID

4285

23026

Gene namemitochondrial intermediate peptidasemyosin XVI
SynonymsCOXPD31|HMIP|MIPMYAP3|MYR8|Myo16b|NYAP3|PPP1R107
Cytomap

13q12.12

13q33.3

Type of geneprotein-codingprotein-coding
Descriptionmitochondrial intermediate peptidaseunconventional myosin-XVIMYO16 variant proteinmyosin heavy chain Myr 8neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 3protein phosphatase 1, regulatory subunit 10
Modification date2020031320200313
UniProtAcc

Q99797

Q9Y6X6

Ensembl transtripts involved in fusion geneENST00000382172, ENST00000469167, 
ENST00000457511, ENST00000467639, 
ENST00000251041, ENST00000356711, 
ENST00000357550, 
Fusion gene scores* DoF score7 X 7 X 6=29418 X 19 X 10=3420
# samples 721
** MAII scorelog2(7/294*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(21/3420*10)=-4.02553509210714
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MIPEP [Title/Abstract] AND MYO16 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMIPEP(24380089)-MYO16(109507791), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MIPEP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MYO16 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-DM-A28F-01AMIPEPchr13

24380089

-MYO16chr13

109507791

+


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Fusion Gene ORF analysis for MIPEP-MYO16

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000382172ENST00000457511MIPEPchr13

24380089

-MYO16chr13

109507791

+
5CDS-intronENST00000382172ENST00000467639MIPEPchr13

24380089

-MYO16chr13

109507791

+
In-frameENST00000382172ENST00000251041MIPEPchr13

24380089

-MYO16chr13

109507791

+
In-frameENST00000382172ENST00000356711MIPEPchr13

24380089

-MYO16chr13

109507791

+
In-frameENST00000382172ENST00000357550MIPEPchr13

24380089

-MYO16chr13

109507791

+
intron-3CDSENST00000469167ENST00000251041MIPEPchr13

24380089

-MYO16chr13

109507791

+
intron-3CDSENST00000469167ENST00000356711MIPEPchr13

24380089

-MYO16chr13

109507791

+
intron-3CDSENST00000469167ENST00000357550MIPEPchr13

24380089

-MYO16chr13

109507791

+
intron-intronENST00000469167ENST00000457511MIPEPchr13

24380089

-MYO16chr13

109507791

+
intron-intronENST00000469167ENST00000467639MIPEPchr13

24380089

-MYO16chr13

109507791

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000382172MIPEPchr1324380089-ENST00000356711MYO16chr13109507791+75131947963412110
ENST00000382172MIPEPchr1324380089-ENST00000251041MYO16chr13109507791+42161947935871192
ENST00000382172MIPEPchr1324380089-ENST00000357550MYO16chr13109507791+74991947963412110

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000382172ENST00000356711MIPEPchr1324380089-MYO16chr13109507791+0.000618670.9993813
ENST00000382172ENST00000251041MIPEPchr1324380089-MYO16chr13109507791+0.0007044610.9992955
ENST00000382172ENST00000357550MIPEPchr1324380089-MYO16chr13109507791+0.0006333930.9993666

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Fusion Genomic Features for MIPEP-MYO16


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MIPEP-MYO16


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:24380089/chr13:109507791)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MIPEP

Q99797

MYO16

Q9Y6X6

FUNCTION: Cleaves proteins, imported into the mitochondrion, to their mature size.FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMYO16chr13:24380089chr13:109507791ENST000002510418241389_1671394941.0Compositional biasPro-rich
TgeneMYO16chr13:24380089chr13:109507791ENST000003567119351389_16713941859.0Compositional biasPro-rich
TgeneMYO16chr13:24380089chr13:109507791ENST000003575508341389_16713941859.0Compositional biasPro-rich
TgeneMYO16chr13:24380089chr13:109507791ENST000002510418241147_1176394941.0DomainIQ
TgeneMYO16chr13:24380089chr13:109507791ENST00000251041824401_1145394941.0DomainMyosin motor
TgeneMYO16chr13:24380089chr13:109507791ENST000003567119351147_11763941859.0DomainIQ
TgeneMYO16chr13:24380089chr13:109507791ENST00000356711935401_11453941859.0DomainMyosin motor
TgeneMYO16chr13:24380089chr13:109507791ENST000003575508341147_11763941859.0DomainIQ
TgeneMYO16chr13:24380089chr13:109507791ENST00000357550834401_11453941859.0DomainMyosin motor
TgeneMYO16chr13:24380089chr13:109507791ENST00000251041824497_504394941.0Nucleotide bindingATP
TgeneMYO16chr13:24380089chr13:109507791ENST00000356711935497_5043941859.0Nucleotide bindingATP
TgeneMYO16chr13:24380089chr13:109507791ENST00000357550834497_5043941859.0Nucleotide bindingATP
TgeneMYO16chr13:24380089chr13:109507791ENST000002510418241111_1377394941.0RegionInvolved in CYFIP1- and NCKAP1-binding
TgeneMYO16chr13:24380089chr13:109507791ENST000003567119351111_13773941859.0RegionInvolved in CYFIP1- and NCKAP1-binding
TgeneMYO16chr13:24380089chr13:109507791ENST000003575508341111_13773941859.0RegionInvolved in CYFIP1- and NCKAP1-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMYO16chr13:24380089chr13:109507791ENST00000251041824125_154394941.0RepeatANK 3
TgeneMYO16chr13:24380089chr13:109507791ENST00000251041824158_189394941.0RepeatANK 4
TgeneMYO16chr13:24380089chr13:109507791ENST00000251041824191_217394941.0RepeatANK 5
TgeneMYO16chr13:24380089chr13:109507791ENST00000251041824221_250394941.0RepeatANK 6
TgeneMYO16chr13:24380089chr13:109507791ENST00000251041824254_283394941.0RepeatANK 7
TgeneMYO16chr13:24380089chr13:109507791ENST0000025104182459_88394941.0RepeatANK 1
TgeneMYO16chr13:24380089chr13:109507791ENST0000025104182492_121394941.0RepeatANK 2
TgeneMYO16chr13:24380089chr13:109507791ENST00000356711935125_1543941859.0RepeatANK 3
TgeneMYO16chr13:24380089chr13:109507791ENST00000356711935158_1893941859.0RepeatANK 4
TgeneMYO16chr13:24380089chr13:109507791ENST00000356711935191_2173941859.0RepeatANK 5
TgeneMYO16chr13:24380089chr13:109507791ENST00000356711935221_2503941859.0RepeatANK 6
TgeneMYO16chr13:24380089chr13:109507791ENST00000356711935254_2833941859.0RepeatANK 7
TgeneMYO16chr13:24380089chr13:109507791ENST0000035671193559_883941859.0RepeatANK 1
TgeneMYO16chr13:24380089chr13:109507791ENST0000035671193592_1213941859.0RepeatANK 2
TgeneMYO16chr13:24380089chr13:109507791ENST00000357550834125_1543941859.0RepeatANK 3
TgeneMYO16chr13:24380089chr13:109507791ENST00000357550834158_1893941859.0RepeatANK 4
TgeneMYO16chr13:24380089chr13:109507791ENST00000357550834191_2173941859.0RepeatANK 5
TgeneMYO16chr13:24380089chr13:109507791ENST00000357550834221_2503941859.0RepeatANK 6
TgeneMYO16chr13:24380089chr13:109507791ENST00000357550834254_2833941859.0RepeatANK 7
TgeneMYO16chr13:24380089chr13:109507791ENST0000035755083459_883941859.0RepeatANK 1
TgeneMYO16chr13:24380089chr13:109507791ENST0000035755083492_1213941859.0RepeatANK 2


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Fusion Gene Sequence for MIPEP-MYO16


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>53744_53744_1_MIPEP-MYO16_MIPEP_chr13_24380089_ENST00000382172_MYO16_chr13_109507791_ENST00000251041_length(transcript)=4216nt_BP=1947nt
CGGCGTGGGCTGCTGCCTTGGAAACGCGGAGCGCGCGCTCCCAGCGAAAGCAGCAGGGCAGGGATCTGCGTTGGAGGAAGGGACTGCTCT
GGTGCTAGAATGCTGTGCGTCGGAAGGCTGGGCGGCTTGGGAGCCAGAGCAGCAGCTCTGCCGCCCCGCCGGGCGGGCCGGGGAAGCCTC
GAAGCCGGGATCCGGGCCCGAAGGGTCAGCACCAGCTGGTCTCCCGTGGGCGCCGCCTTCAATGTCAAGCCCCAGGGCAGCCGCTTGGAC
CTGTTCGGCGAGCGCCGGGGTCTTTTTGGAGTTCCTGAGCTGAGTGCCCCAGAAGGATTTCATATTGCACAAGAAAAAGCCTTGAGAAAG
ACAGAATTGCTTGTGGACCGTGCATGTTCCACCCCACCTGGGCCCCAGACCGTGCTGATCTTCGATGAGCTCTCGGATTCCTTATGCAGA
GTGGCCGACTTGGCTGATTTTGTGAAAATCGCTCACCCTGAGCCAGCATTCAGAGAAGCTGCGGAAGAAGCTTGTAGAAGTATTGGCACC
ATGGTAGAGAAGTTGAACACAAATGTGGATTTATATCAAAGTTTGCAAAAATTACTAGCTGATAAAAAACTTGTGGATTCCCTTGATCCA
GAAACAAGGCGAGTGGCTGAACTGTTTATGTTTGATTTTGAAATTAGTGGAATCCATCTAGACAAAGAAAAGCGTAAAAGAGCAGTGGAC
CTCAATGTTAAAATCTTGGATTTGAGTAGTACATTTCTTATGGGAACCAATTTTCCCAACAAGATTGAGAAGCATCTCTTACCAGAACAC
ATTCGTCGTAACTTTACATCTGCTGGGGATCATATCATAATTGATGGTCTCCACGCAGAATCACCAGATGACTTGGTGCGAGAAGCTGCT
TATAAAATTTTTCTTTATCCCAATGCTGGTCAATTGAAATGTTTAGAAGAATTGCTCAGCAGCAGAGATCTTCTGGCAAAGTTGGTGGGG
TATTCCACGTTTTCTCACAGGGCTCTCCAAGGAACGATAGCTAAAAATCCAGAGACTGTCATGCAGTTCCTTGAAAAACTATCTGACAAA
CTTTCTGAAAGAACTCTGAAAGATTTTGAGATGATACGAGGGATGAAAATGAAACTGAATCCTCAAAATTCCGAAGTAATGCCCTGGGAC
CCCCCTTACTACAGTGGTGTGATTCGTGCAGAAAGGTATAATATTGAGCCCAGCCTATATTGCCCGTTTTTCTCTCTTGGAGCATGCATG
GAAGGCCTGAATATTTTGCTTAACAGACTGTTGGGGATTTCATTATATGCAGAGCAGCCTGCAAAAGGAGAGGTGTGGAGCGAAGATGTC
CGAAAACTGGCTGTTGTTCATGAATCTGAAGGATTGTTGGGGTACATTTACTGTGATTTTTTTCAGCGAGCAGACAAACCACATCAGGAT
TGCCATTTCACTATCCGTGGAGGCAGACTAAAGGAAGATGGAGACTATCAACTCCCAGTTGTAGTTCTTATGCTGAATCTTCCCCGTTCC
TCAAGGAGTTCTCCAACTTTGCTAACTCCTAGCATGATGGAAAATCTTTTCCATGAAATGGGACATGCCATGCATTCAATGCTAGGACGT
ACTCGTTACCAACACGTCACTGGGACCAGGTGCCCTACTGATTTTGCTGAGGTTCCTTCTATTCTGATGGAGTACTTTGCAAATGATTAT
CGAGTAGTTAACCAATTTGCCAGACATTATCAGACTGGACAGCCACTGCCAAAAAATATGGTGTCTCGTCTTTGTGAATCTAAAAAGGTT
TGTGCTGCAGCTGATATGCAACTTCAGGTCTTTTATGCCACTCTGGATCAAATCTACCATGGGAAGCATCCCCTGAGGAATTCAACCACA
GACATTCTCAAGGAAACACAAGAGAAATTCTATGGCCTACCATATGTTCCAAATACTGTCAAGCTAATGCCTCCTGCCCCAAACGATGAC
CTGGCAACGCTCAGCGAGCTCAATGATGGCAGCCTGCTCTATGAGATTCAGAAGCGCTTTGGGAACAATCAGATCTATACATTCATTGGA
GACATTCTTTTGCTTGTTAACCCATACAAGGAGCTTCCAATTTATTCTTCCATGGTGTCCCAGCTGTATTTCAGCTCCTCAGGGAAGCTG
TGTTCCTCGCTGCCTCCTCACCTCTTCTCCTGTGTGGAGAGAGCCTTTCACCAGCTCTTCCGGGAACAGCGGCCTCAGTGTTTCATCCTC
AGTGGAGAAAGGGGATCAGGAAAGTCTGAAGCCAGCAAACAAATCATAAGACACCTCACCTGCAGGGCTGGCGCCAGCAGGGCCACACTG
GATTCCAGATTCAAACATGTCGTGTGCATCTTAGAAGCCTTTGGACATGCCAAGACCACACTTAATGATTTGTCCAGTTGCTTCATCAAG
TATTTTGAACTGCAGTTCTGTGAGAGGAAACAACAGCTAACCGGAGCCAGAATTTATACATATTTGCTAGAGAAATCCAGACTTGTTTCA
CAACCTCTTGGCCAGAGCAATTTTCTCATTTTCTACTTGTTGATGGATGGGTTATCTGCTGAAGAAAAATATGGACTTCATCTTAATAAT
TTATGTGCACACCGGTATTTGAACCAGACCATACAGGATGATGCATCCACAGGGGAGCGTTCTCTGAACAGGGAGAAATTGGCTGTTTTG
AAACGAGCCCTGAATGTAGTTGGCTTCAGCAGCTTGGAGGTGGAGAATCTGTTCGTAATTCTAGCAGCAATATTGCACCTTGGAGACATT
CGGTTTACTGCCCTGAATGAGGGGAACTCCGCCTTCGTTTCTGACCTCCAGCTCCTGGAACAAGTGGCTGGAATGTTACAAGTATCAACA
GATGAATTGGCATCTGCCTTAACAACTGATATTCAATATTTTAAAGGGGATATGATAATACGACGACATACCATACAGATTGCTGAGTTT
TTCCGAGACCTCTTGGCCAAGTCCCTGTACAGTCGTTTGTTTAGCTTTTTGGTGAATACCATGAATTCTTGCCTCCACAGTCAAGATGAA
CAGAAAAGCATGCAGACATTGGATATTGGAATATTGGACATTTTTGGTTTTGAAGAGTTTCAAAAGAATGAATTTGAACAACTTTGTGTC
AACATGACCAATGAGAAGATGCACCACTATATCAATGAAGTGCTTTTTCTCCACGAGCAAGTGGAATGTGTACAAGAGGGAGTTACCATG
GAAACAGCATATTCTCCTGGTAACCAGAATGGAGTTTTGGACTTTTTTTTCCAGAAGCCATCTGGATTTCTCACCTTATTGGATGAAGAA
AGTCAAATGATTTGGTCAGTGGAATCAAATTTTCCAAAAAAACTACAAAGTCTCCTAGAATCCTCAAACACAAATGCGGTGTACTCCCCC
ATGAAGGATGGGAATGGGAATGTTGCCCTCAAAGACCACGGTACAGCCTTCACCATCATGCACTACGCAGGAAGGGTAATGTATGATGTT
GTTGGGGCGATTGAAAAAAATAAAGACTCCCTTTCACAGAATCTTCTATTTGTAATGAAAAGAGGAAGGTGCTTCTGAGCAAAAGGACAG
AATTTACAATGTACCCTTTTGTATTTATACAGGAGGTGTCAGATTTTTTTTTTTGTAAAGGGCTAGAGAATAAATATTTTAGACCTTGTG
CACCATAAGATCCTTGTTGCAGTTACTCACCTCTGCTGTTATAATGTGAAAAACAGCTGTAGACAATACAAATGGATGTGACTGTATTCT
GATAAAATTTTATTTACAAAAACAGGCAGTGGGCCATGTTTGGCTCAGGAGCCATGATTGCTCACTCACTCTATCATAAAAGCAAAATAT
TTGTGGTTGCCATCATGTTTTATGAATCTGTGAAATACTTTGATGCTTGTACATATTTATTAAAAGCAAGTGTAATTCATAAATAATAAT
TTTTATTTGCAGGTACTTTGCTTATAGTATCTAATTCAATTTTCGTAGCATCAAAAAGCTCCCAGTTGAGGAAGATGGTGAGGTCTGTTG
TAGAATGTACACAAGCAGAGCTGAGTCTCTGAGACCACTAACCAGGTACAGTCAGGGAGCTTGGAGACAGCTCATAGAGACACACAGCAA

>53744_53744_1_MIPEP-MYO16_MIPEP_chr13_24380089_ENST00000382172_MYO16_chr13_109507791_ENST00000251041_length(amino acids)=1192AA_BP=646
MLPWKRGARAPSESSRAGICVGGRDCSGARMLCVGRLGGLGARAAALPPRRAGRGSLEAGIRARRVSTSWSPVGAAFNVKPQGSRLDLFG
ERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRACSTPPGPQTVLIFDELSDSLCRVADLADFVKIAHPEPAFREAAEEACRSIGTMVE
KLNTNVDLYQSLQKLLADKKLVDSLDPETRRVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPNKIEKHLLPEHIRR
NFTSAGDHIIIDGLHAESPDDLVREAAYKIFLYPNAGQLKCLEELLSSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEKLSDKLSE
RTLKDFEMIRGMKMKLNPQNSEVMPWDPPYYSGVIRAERYNIEPSLYCPFFSLGACMEGLNILLNRLLGISLYAEQPAKGEVWSEDVRKL
AVVHESEGLLGYIYCDFFQRADKPHQDCHFTIRGGRLKEDGDYQLPVVVLMLNLPRSSRSSPTLLTPSMMENLFHEMGHAMHSMLGRTRY
QHVTGTRCPTDFAEVPSILMEYFANDYRVVNQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQLQVFYATLDQIYHGKHPLRNSTTDIL
KETQEKFYGLPYVPNTVKLMPPAPNDDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSGKLCSS
LPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRATLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFE
LQFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREKLAVLKRA
LNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRD
LLAKSLYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMETA
YSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGA

--------------------------------------------------------------
>53744_53744_2_MIPEP-MYO16_MIPEP_chr13_24380089_ENST00000382172_MYO16_chr13_109507791_ENST00000356711_length(transcript)=7513nt_BP=1947nt
CGGCGTGGGCTGCTGCCTTGGAAACGCGGAGCGCGCGCTCCCAGCGAAAGCAGCAGGGCAGGGATCTGCGTTGGAGGAAGGGACTGCTCT
GGTGCTAGAATGCTGTGCGTCGGAAGGCTGGGCGGCTTGGGAGCCAGAGCAGCAGCTCTGCCGCCCCGCCGGGCGGGCCGGGGAAGCCTC
GAAGCCGGGATCCGGGCCCGAAGGGTCAGCACCAGCTGGTCTCCCGTGGGCGCCGCCTTCAATGTCAAGCCCCAGGGCAGCCGCTTGGAC
CTGTTCGGCGAGCGCCGGGGTCTTTTTGGAGTTCCTGAGCTGAGTGCCCCAGAAGGATTTCATATTGCACAAGAAAAAGCCTTGAGAAAG
ACAGAATTGCTTGTGGACCGTGCATGTTCCACCCCACCTGGGCCCCAGACCGTGCTGATCTTCGATGAGCTCTCGGATTCCTTATGCAGA
GTGGCCGACTTGGCTGATTTTGTGAAAATCGCTCACCCTGAGCCAGCATTCAGAGAAGCTGCGGAAGAAGCTTGTAGAAGTATTGGCACC
ATGGTAGAGAAGTTGAACACAAATGTGGATTTATATCAAAGTTTGCAAAAATTACTAGCTGATAAAAAACTTGTGGATTCCCTTGATCCA
GAAACAAGGCGAGTGGCTGAACTGTTTATGTTTGATTTTGAAATTAGTGGAATCCATCTAGACAAAGAAAAGCGTAAAAGAGCAGTGGAC
CTCAATGTTAAAATCTTGGATTTGAGTAGTACATTTCTTATGGGAACCAATTTTCCCAACAAGATTGAGAAGCATCTCTTACCAGAACAC
ATTCGTCGTAACTTTACATCTGCTGGGGATCATATCATAATTGATGGTCTCCACGCAGAATCACCAGATGACTTGGTGCGAGAAGCTGCT
TATAAAATTTTTCTTTATCCCAATGCTGGTCAATTGAAATGTTTAGAAGAATTGCTCAGCAGCAGAGATCTTCTGGCAAAGTTGGTGGGG
TATTCCACGTTTTCTCACAGGGCTCTCCAAGGAACGATAGCTAAAAATCCAGAGACTGTCATGCAGTTCCTTGAAAAACTATCTGACAAA
CTTTCTGAAAGAACTCTGAAAGATTTTGAGATGATACGAGGGATGAAAATGAAACTGAATCCTCAAAATTCCGAAGTAATGCCCTGGGAC
CCCCCTTACTACAGTGGTGTGATTCGTGCAGAAAGGTATAATATTGAGCCCAGCCTATATTGCCCGTTTTTCTCTCTTGGAGCATGCATG
GAAGGCCTGAATATTTTGCTTAACAGACTGTTGGGGATTTCATTATATGCAGAGCAGCCTGCAAAAGGAGAGGTGTGGAGCGAAGATGTC
CGAAAACTGGCTGTTGTTCATGAATCTGAAGGATTGTTGGGGTACATTTACTGTGATTTTTTTCAGCGAGCAGACAAACCACATCAGGAT
TGCCATTTCACTATCCGTGGAGGCAGACTAAAGGAAGATGGAGACTATCAACTCCCAGTTGTAGTTCTTATGCTGAATCTTCCCCGTTCC
TCAAGGAGTTCTCCAACTTTGCTAACTCCTAGCATGATGGAAAATCTTTTCCATGAAATGGGACATGCCATGCATTCAATGCTAGGACGT
ACTCGTTACCAACACGTCACTGGGACCAGGTGCCCTACTGATTTTGCTGAGGTTCCTTCTATTCTGATGGAGTACTTTGCAAATGATTAT
CGAGTAGTTAACCAATTTGCCAGACATTATCAGACTGGACAGCCACTGCCAAAAAATATGGTGTCTCGTCTTTGTGAATCTAAAAAGGTT
TGTGCTGCAGCTGATATGCAACTTCAGGTCTTTTATGCCACTCTGGATCAAATCTACCATGGGAAGCATCCCCTGAGGAATTCAACCACA
GACATTCTCAAGGAAACACAAGAGAAATTCTATGGCCTACCATATGTTCCAAATACTGTCAAGCTAATGCCTCCTGCCCCAAACGATGAC
CTGGCAACGCTCAGCGAGCTCAATGATGGCAGCCTGCTCTATGAGATTCAGAAGCGCTTTGGGAACAATCAGATCTATACATTCATTGGA
GACATTCTTTTGCTTGTTAACCCATACAAGGAGCTTCCAATTTATTCTTCCATGGTGTCCCAGCTGTATTTCAGCTCCTCAGGGAAGCTG
TGTTCCTCGCTGCCTCCTCACCTCTTCTCCTGTGTGGAGAGAGCCTTTCACCAGCTCTTCCGGGAACAGCGGCCTCAGTGTTTCATCCTC
AGTGGAGAAAGGGGATCAGGAAAGTCTGAAGCCAGCAAACAAATCATAAGACACCTCACCTGCAGGGCTGGCGCCAGCAGGGCCACACTG
GATTCCAGATTCAAACATGTCGTGTGCATCTTAGAAGCCTTTGGACATGCCAAGACCACACTTAATGATTTGTCCAGTTGCTTCATCAAG
TATTTTGAACTGCAGTTCTGTGAGAGGAAACAACAGCTAACCGGAGCCAGAATTTATACATATTTGCTAGAGAAATCCAGACTTGTTTCA
CAACCTCTTGGCCAGAGCAATTTTCTCATTTTCTACTTGTTGATGGATGGGTTATCTGCTGAAGAAAAATATGGACTTCATCTTAATAAT
TTATGTGCACACCGGTATTTGAACCAGACCATACAGGATGATGCATCCACAGGGGAGCGTTCTCTGAACAGGGAGAAATTGGCTGTTTTG
AAACGAGCCCTGAATGTAGTTGGCTTCAGCAGCTTGGAGGTGGAGAATCTGTTCGTAATTCTAGCAGCAATATTGCACCTTGGAGACATT
CGGTTTACTGCCCTGAATGAGGGGAACTCCGCCTTCGTTTCTGACCTCCAGCTCCTGGAACAAGTGGCTGGAATGTTACAAGTATCAACA
GATGAATTGGCATCTGCCTTAACAACTGATATTCAATATTTTAAAGGGGATATGATAATACGACGACATACCATACAGATTGCTGAGTTT
TTCCGAGACCTCTTGGCCAAGTCCCTGTACAGTCGTTTGTTTAGCTTTTTGGTGAATACCATGAATTCTTGCCTCCACAGTCAAGATGAA
CAGAAAAGCATGCAGACATTGGATATTGGAATATTGGACATTTTTGGTTTTGAAGAGTTTCAAAAGAATGAATTTGAACAACTTTGTGTC
AACATGACCAATGAGAAGATGCACCACTATATCAATGAAGTGCTTTTTCTCCACGAGCAAGTGGAATGTGTACAAGAGGGAGTTACCATG
GAAACAGCATATTCTCCTGGTAACCAGAATGGAGTTTTGGACTTTTTTTTCCAGAAGCCATCTGGATTTCTCACCTTATTGGATGAAGAA
AGTCAAATGATTTGGTCAGTGGAATCAAATTTTCCAAAAAAACTACAAAGTCTCCTAGAATCCTCAAACACAAATGCGGTGTACTCCCCC
ATGAAGGATGGGAATGGGAATGTTGCCCTCAAAGACCACGGTACAGCCTTCACCATCATGCACTACGCAGGAAGGGTAATGTATGATGTT
GTTGGGGCGATTGAAAAAAATAAAGACTCCCTTTCACAGAATCTTCTATTTGTAATGAAAACTAGTGAAAATGTCGTGATCAATCATTTG
TTCCAGTCGAAATTGTCACAAACAGGATCCCTCGTATCTGCCTATCCTTCCTTTAAATTCCGAGGACATAAGTCTGCCCTGCTCAGTAAG
AAAATGACAGCTTCTTCAATTATTGGAGAAAACAAGAATTATCTAGAACTTAGTAAGTTATTAAAAAAGAAAGGAACTTCTACATTTCTT
CAAAGATTGGAACGAGGAGATCCAGTCACCATAGCATCACAACTCAGGAAATCACTAATGGATATTATTGGAAAACTTCAGAAGTGCACT
CCACACTTCATTCATTGCATCAGGCCCAATAACTCAAAGCTGCCAGATACTTTTGATAATTTTTACGTGTCTGCTCAGCTACAATATATT
GGGGTCCTGGAGATGGTGAAGATCTTCCGATATGGATACCCTGTTCGCCTTTCCTTCTCGGATTTCCTGTCAAGGTATAAGCCACTGGCT
GATACATTCCTGCGTGAGAAGAAGGAACAGTCAGCTGCCGAGCGATGTCGACTTGTTCTCCAGCAGTGTAAATTACAAGGCTGGCAGATG
GGAGTCCGAAAAGTGTTTCTAAAATACTGGCATGCTGACCAACTCAATGATTTGTGCCTACAGTTGCAGAGAAAAATTATAACCTGCCAA
AAAGTTATCAGAGGATTTTTAGCACGCCAGCACCTGCTTCAGAGAATAAGCATCAGACAACAAGAGGTGACTTCTATCAATAGCTTTCTG
CAGAACACAGAGGACATGGGGCTGAAAACCTACGATGCCCTGGTCATTCAGAATGCTTCAGACATTGCCCGGGAAAATGACCGGCTCCGT
AGTGAAATGAACGCTCCCTACCATAAAGAGAAGTTAGAGGTCAGGAACATGCAAGAGGAAGGAAGCAAAAGAACCGATGACAAGAGTGGA
CCCAGGCATTTCCACCCCAGCTCCATGTCAGTCTGCGCGGCCGTGGATGGCCTGGGCCAGTGCCTCGTTGGCCCGTCCATCTGGTCTCCT
TCGCTGCACTCGGTGTTCAGCATGGATGACAGCAGCAGCCTCCCGTCTCCACGGAAACAGCCCCCGCCCAAGCCAAAGAGGGACCCCAAC
ACCCGGCTGAGTGCTTCCTATGAGGCTGTGAGCGCCTGCCTCTCCGCGGCCAGGGAAGCGGCCAACGAAGCTCTGGCCCGGCCCAGACCG
CACAGCGACGACTACAGCACCATGAAGAAGATTCCTCCTCGAAAGCCCAAGCGCAGCCCCAACACCAAGCTCAGCGGCTCCTACGAGGAG
ATATCGGGGTCCCGGCCCGGGGACGCGAGGCCCGCGGGCGCCCCGGGGGCAGCAGCGCGCGTTCTGACCCCCGGGACTCCGCAGTGCGCG
CTGCCCCCGGCGGCGCCTCCGGGTGACGAGGACGACAGCGAGCCTGTGTACATCGAGATGCTGGGGCACGCGGCCAGGCCCGATAGCCCG
GACCCCGGGGAGTCCGTGTACGAGGAGATGAAGTGTTGCCTGCCCGACGACGGCGGCCCGGGCGCGGGCTCCTTCCTGCTCCACGGCGCA
TCGCCGCCCCTGCTCCACCGCGCGCCGGAGGACGAGGCGGCGGGGCCCCCAGGGGACGCGTGCGACATCCCGCCGCCCTTCCCCAACCTG
CTGCCGCACCGGCCGCCCCTGCTGGTGTTCCCCCCGACCCCCGTCACCTGCTCCCCCGCCTCCGACGAGTCGCCCCTGACACCCCTGGAG
GTGAAGAAGCTGCCAGTCCTGGAGACCAACCTCAAGTACCCCGTGCAGCCGGAGGGGTCGAGCCCGCTGTCCCCGCAGTACTCCAAGAGC
CAGAAGGGCGACGGCGACAGGCCCGCGTCCCCCGGCCTGGCGCTGTTCAACGGGTCCGGCCGAGCCTCCCCGCCGTCCACGCCGCCCCCG
CCCCCGCCCCCGCCCGGGCCGCCCCCCGCGCCCTACAGGCCCTGCGCGCACTTGGCCTTCCCGCCGGAGCCCGCCCCGGTGAACGCGGGG
AAAGCGGGGCCGAGCGCAGAGGCGCCCAAGGTTCACCCAAAGCCAAACTCTGCCCCCGTGGCCGGGCCCTGCAGCTCCTTCCCCAAGATC
CCATATTCCCCCGTGAAGGCCACCAGGGCGGACGCCAGGAAGGCCGGCTCCAGTGCCTCGCCCCCCGCGCCCTACAGCCCTCCCAGCTCC
AGGCCTCTCAGCAGCCCCCTGGACGAGCTCGCCAGCCTCTTCAACTCGGGGAGGAGTGTGCTTCGGAAATCCGCGGCGGGAAGAAAAATC
AGGGAAGCAGAAGGTTTTGAAACTAACATGAACATAAGTAGCCGAGATGACCCTAGTACGTCAGAAATTACTTCCGAGACTCAAGACAGA
AATGCAAATAACCATGGAATTCAGTTATCTAATTCACTATCTAGTGCTATAACTGCTGAAAATGGAAATTCCATCTCAAATGGTTTACCT
GAAGAAGATGGATACTCACGGTTGTCTATAAGTGGCACAGGGACTTCGACATTTCAAAGACACAGGGACAGTCACACCACTCAGGTAATC
CATCAGCTGAGGCTCTCAGAGAATGAAAGTGTGGCCCTGCAGGAACTCTTGGACTGGAGGAGAAAGCTCTGTGAGGAAGGACAAGACTGG
CAGCAGATCCTGCACCACGCTGAGCCCAGGGTGCCTCCCCCACCACCTTGCAAGAAGCCCAGCCTTCTGAAGAAGCCGGAAGGGGCCTCC
TGCAACAGGCTGCCGTCTGAGCTCTGGGACACCACCATTTGATGTGGCCTGAACTGCAGACTTACAAAATAGAACTGCCTACTGATTCCG
GGCTGCAACAACAGAAGGCTGCCTTCTGACATGCGCTGGGGCTTCTCTCCACGCATTTAGACAAAAAAAGCACAGGACACAGACACTAAA
TATATGAGATCCCGTGTGTGTGTGTGTGTGTTTGTGTGTGTGTGTGTGGGTTCTTTCTTATCCATCTCGTGGTGATACACTCTGATTTTC
AAGCTCCTCATTTACGGCTCTGTGCTACCCCTAGGTAGCAAGAGAGAGGCTGGGAAAAGTGTGGACGTGGCCAGAGCGAGAGAGTAGCGG
AGGAAAGGAGCAATCCATGCACACTCTGTACAGTTGTTTTTCTACGGTTCAACAGTCTGTTTATTGTACTTCCAATGGTTTTATTATAAT
ACAGTATACGGGACATATATTTTATTTCTTTGTAGCTACTTGTGTTTTATTGGTATTATAAACCTGATAATTATTTACATGTTTATTACT
GTAATTTTATAAATTTATGCAATTGGTGGTGCTTCCTTTCTTCAAAATACAGATTTTAAAAAATCATTTCTAGATTATTTTTTTCCTCCA
CAGTCCTTTTTTTTCACCTAACGCACCTAAATCTTGAAACTACATTGTTGTTTTAGCTTCGCCAGTGTCACCCCTTGCAAAACTATGAAT
TGAGCCCCATGTTTTAGGTGTTACTCATGGATGAGGAGGCTGTTCTTTCCTATGCCCTGTATTTCTGGATAAGTGGATTGTGTACCCTTT
AGTTAAATTTCACCTCCCGACTTCAGCATAGATCACAGGAAATCACATGGCACACGGTTAAACACGTATGGCTTCAAATCCATAGCCGGT
GGTGTAAAATGATCATATTCATTCAAAGGCCTACACAGTACAAATGAGCACGCTGCCATGTACTGGTTTGAGCAGTAGGGGCTGCATCGC
ACAGCGCTCGTCCCCCGGGACTTACACTGCATGATTCCCTCACTGTATATCCTCAACCCTCCCATAATGCAAGGCCTTGTTCATTGATGT
GCTTTCGTCGGCTGTCGGAAAGTTCTGAGCAGTGGCTCCAGACCACCTTGTCTTGCTACTTGGAACTTTTTATTCATACCAGCCTTTGAA

>53744_53744_2_MIPEP-MYO16_MIPEP_chr13_24380089_ENST00000382172_MYO16_chr13_109507791_ENST00000356711_length(amino acids)=2110AA_BP=646
MLPWKRGARAPSESSRAGICVGGRDCSGARMLCVGRLGGLGARAAALPPRRAGRGSLEAGIRARRVSTSWSPVGAAFNVKPQGSRLDLFG
ERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRACSTPPGPQTVLIFDELSDSLCRVADLADFVKIAHPEPAFREAAEEACRSIGTMVE
KLNTNVDLYQSLQKLLADKKLVDSLDPETRRVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPNKIEKHLLPEHIRR
NFTSAGDHIIIDGLHAESPDDLVREAAYKIFLYPNAGQLKCLEELLSSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEKLSDKLSE
RTLKDFEMIRGMKMKLNPQNSEVMPWDPPYYSGVIRAERYNIEPSLYCPFFSLGACMEGLNILLNRLLGISLYAEQPAKGEVWSEDVRKL
AVVHESEGLLGYIYCDFFQRADKPHQDCHFTIRGGRLKEDGDYQLPVVVLMLNLPRSSRSSPTLLTPSMMENLFHEMGHAMHSMLGRTRY
QHVTGTRCPTDFAEVPSILMEYFANDYRVVNQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQLQVFYATLDQIYHGKHPLRNSTTDIL
KETQEKFYGLPYVPNTVKLMPPAPNDDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSGKLCSS
LPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRATLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFE
LQFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREKLAVLKRA
LNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRD
LLAKSLYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMETA
YSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGA
IEKNKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKKKGTSTFLQRL
ERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTF
LREKKEQSAAERCRLVLQQCKLQGWQMGVRKVFLKYWHADQLNDLCLQLQRKIITCQKVIRGFLARQHLLQRISIRQQEVTSINSFLQNT
EDMGLKTYDALVIQNASDIARENDRLRSEMNAPYHKEKLEVRNMQEEGSKRTDDKSGPRHFHPSSMSVCAAVDGLGQCLVGPSIWSPSLH
SVFSMDDSSSLPSPRKQPPPKPKRDPNTRLSASYEAVSACLSAAREAANEALARPRPHSDDYSTMKKIPPRKPKRSPNTKLSGSYEEISG
SRPGDARPAGAPGAAARVLTPGTPQCALPPAAPPGDEDDSEPVYIEMLGHAARPDSPDPGESVYEEMKCCLPDDGGPGAGSFLLHGASPP
LLHRAPEDEAAGPPGDACDIPPPFPNLLPHRPPLLVFPPTPVTCSPASDESPLTPLEVKKLPVLETNLKYPVQPEGSSPLSPQYSKSQKG
DGDRPASPGLALFNGSGRASPPSTPPPPPPPPGPPPAPYRPCAHLAFPPEPAPVNAGKAGPSAEAPKVHPKPNSAPVAGPCSSFPKIPYS
PVKATRADARKAGSSASPPAPYSPPSSRPLSSPLDELASLFNSGRSVLRKSAAGRKIREAEGFETNMNISSRDDPSTSEITSETQDRNAN
NHGIQLSNSLSSAITAENGNSISNGLPEEDGYSRLSISGTGTSTFQRHRDSHTTQVIHQLRLSENESVALQELLDWRRKLCEEGQDWQQI

--------------------------------------------------------------
>53744_53744_3_MIPEP-MYO16_MIPEP_chr13_24380089_ENST00000382172_MYO16_chr13_109507791_ENST00000357550_length(transcript)=7499nt_BP=1947nt
CGGCGTGGGCTGCTGCCTTGGAAACGCGGAGCGCGCGCTCCCAGCGAAAGCAGCAGGGCAGGGATCTGCGTTGGAGGAAGGGACTGCTCT
GGTGCTAGAATGCTGTGCGTCGGAAGGCTGGGCGGCTTGGGAGCCAGAGCAGCAGCTCTGCCGCCCCGCCGGGCGGGCCGGGGAAGCCTC
GAAGCCGGGATCCGGGCCCGAAGGGTCAGCACCAGCTGGTCTCCCGTGGGCGCCGCCTTCAATGTCAAGCCCCAGGGCAGCCGCTTGGAC
CTGTTCGGCGAGCGCCGGGGTCTTTTTGGAGTTCCTGAGCTGAGTGCCCCAGAAGGATTTCATATTGCACAAGAAAAAGCCTTGAGAAAG
ACAGAATTGCTTGTGGACCGTGCATGTTCCACCCCACCTGGGCCCCAGACCGTGCTGATCTTCGATGAGCTCTCGGATTCCTTATGCAGA
GTGGCCGACTTGGCTGATTTTGTGAAAATCGCTCACCCTGAGCCAGCATTCAGAGAAGCTGCGGAAGAAGCTTGTAGAAGTATTGGCACC
ATGGTAGAGAAGTTGAACACAAATGTGGATTTATATCAAAGTTTGCAAAAATTACTAGCTGATAAAAAACTTGTGGATTCCCTTGATCCA
GAAACAAGGCGAGTGGCTGAACTGTTTATGTTTGATTTTGAAATTAGTGGAATCCATCTAGACAAAGAAAAGCGTAAAAGAGCAGTGGAC
CTCAATGTTAAAATCTTGGATTTGAGTAGTACATTTCTTATGGGAACCAATTTTCCCAACAAGATTGAGAAGCATCTCTTACCAGAACAC
ATTCGTCGTAACTTTACATCTGCTGGGGATCATATCATAATTGATGGTCTCCACGCAGAATCACCAGATGACTTGGTGCGAGAAGCTGCT
TATAAAATTTTTCTTTATCCCAATGCTGGTCAATTGAAATGTTTAGAAGAATTGCTCAGCAGCAGAGATCTTCTGGCAAAGTTGGTGGGG
TATTCCACGTTTTCTCACAGGGCTCTCCAAGGAACGATAGCTAAAAATCCAGAGACTGTCATGCAGTTCCTTGAAAAACTATCTGACAAA
CTTTCTGAAAGAACTCTGAAAGATTTTGAGATGATACGAGGGATGAAAATGAAACTGAATCCTCAAAATTCCGAAGTAATGCCCTGGGAC
CCCCCTTACTACAGTGGTGTGATTCGTGCAGAAAGGTATAATATTGAGCCCAGCCTATATTGCCCGTTTTTCTCTCTTGGAGCATGCATG
GAAGGCCTGAATATTTTGCTTAACAGACTGTTGGGGATTTCATTATATGCAGAGCAGCCTGCAAAAGGAGAGGTGTGGAGCGAAGATGTC
CGAAAACTGGCTGTTGTTCATGAATCTGAAGGATTGTTGGGGTACATTTACTGTGATTTTTTTCAGCGAGCAGACAAACCACATCAGGAT
TGCCATTTCACTATCCGTGGAGGCAGACTAAAGGAAGATGGAGACTATCAACTCCCAGTTGTAGTTCTTATGCTGAATCTTCCCCGTTCC
TCAAGGAGTTCTCCAACTTTGCTAACTCCTAGCATGATGGAAAATCTTTTCCATGAAATGGGACATGCCATGCATTCAATGCTAGGACGT
ACTCGTTACCAACACGTCACTGGGACCAGGTGCCCTACTGATTTTGCTGAGGTTCCTTCTATTCTGATGGAGTACTTTGCAAATGATTAT
CGAGTAGTTAACCAATTTGCCAGACATTATCAGACTGGACAGCCACTGCCAAAAAATATGGTGTCTCGTCTTTGTGAATCTAAAAAGGTT
TGTGCTGCAGCTGATATGCAACTTCAGGTCTTTTATGCCACTCTGGATCAAATCTACCATGGGAAGCATCCCCTGAGGAATTCAACCACA
GACATTCTCAAGGAAACACAAGAGAAATTCTATGGCCTACCATATGTTCCAAATACTGTCAAGCTAATGCCTCCTGCCCCAAACGATGAC
CTGGCAACGCTCAGCGAGCTCAATGATGGCAGCCTGCTCTATGAGATTCAGAAGCGCTTTGGGAACAATCAGATCTATACATTCATTGGA
GACATTCTTTTGCTTGTTAACCCATACAAGGAGCTTCCAATTTATTCTTCCATGGTGTCCCAGCTGTATTTCAGCTCCTCAGGGAAGCTG
TGTTCCTCGCTGCCTCCTCACCTCTTCTCCTGTGTGGAGAGAGCCTTTCACCAGCTCTTCCGGGAACAGCGGCCTCAGTGTTTCATCCTC
AGTGGAGAAAGGGGATCAGGAAAGTCTGAAGCCAGCAAACAAATCATAAGACACCTCACCTGCAGGGCTGGCGCCAGCAGGGCCACACTG
GATTCCAGATTCAAACATGTCGTGTGCATCTTAGAAGCCTTTGGACATGCCAAGACCACACTTAATGATTTGTCCAGTTGCTTCATCAAG
TATTTTGAACTGCAGTTCTGTGAGAGGAAACAACAGCTAACCGGAGCCAGAATTTATACATATTTGCTAGAGAAATCCAGACTTGTTTCA
CAACCTCTTGGCCAGAGCAATTTTCTCATTTTCTACTTGTTGATGGATGGGTTATCTGCTGAAGAAAAATATGGACTTCATCTTAATAAT
TTATGTGCACACCGGTATTTGAACCAGACCATACAGGATGATGCATCCACAGGGGAGCGTTCTCTGAACAGGGAGAAATTGGCTGTTTTG
AAACGAGCCCTGAATGTAGTTGGCTTCAGCAGCTTGGAGGTGGAGAATCTGTTCGTAATTCTAGCAGCAATATTGCACCTTGGAGACATT
CGGTTTACTGCCCTGAATGAGGGGAACTCCGCCTTCGTTTCTGACCTCCAGCTCCTGGAACAAGTGGCTGGAATGTTACAAGTATCAACA
GATGAATTGGCATCTGCCTTAACAACTGATATTCAATATTTTAAAGGGGATATGATAATACGACGACATACCATACAGATTGCTGAGTTT
TTCCGAGACCTCTTGGCCAAGTCCCTGTACAGTCGTTTGTTTAGCTTTTTGGTGAATACCATGAATTCTTGCCTCCACAGTCAAGATGAA
CAGAAAAGCATGCAGACATTGGATATTGGAATATTGGACATTTTTGGTTTTGAAGAGTTTCAAAAGAATGAATTTGAACAACTTTGTGTC
AACATGACCAATGAGAAGATGCACCACTATATCAATGAAGTGCTTTTTCTCCACGAGCAAGTGGAATGTGTACAAGAGGGAGTTACCATG
GAAACAGCATATTCTCCTGGTAACCAGAATGGAGTTTTGGACTTTTTTTTCCAGAAGCCATCTGGATTTCTCACCTTATTGGATGAAGAA
AGTCAAATGATTTGGTCAGTGGAATCAAATTTTCCAAAAAAACTACAAAGTCTCCTAGAATCCTCAAACACAAATGCGGTGTACTCCCCC
ATGAAGGATGGGAATGGGAATGTTGCCCTCAAAGACCACGGTACAGCCTTCACCATCATGCACTACGCAGGAAGGGTAATGTATGATGTT
GTTGGGGCGATTGAAAAAAATAAAGACTCCCTTTCACAGAATCTTCTATTTGTAATGAAAACTAGTGAAAATGTCGTGATCAATCATTTG
TTCCAGTCGAAATTGTCACAAACAGGATCCCTCGTATCTGCCTATCCTTCCTTTAAATTCCGAGGACATAAGTCTGCCCTGCTCAGTAAG
AAAATGACAGCTTCTTCAATTATTGGAGAAAACAAGAATTATCTAGAACTTAGTAAGTTATTAAAAAAGAAAGGAACTTCTACATTTCTT
CAAAGATTGGAACGAGGAGATCCAGTCACCATAGCATCACAACTCAGGAAATCACTAATGGATATTATTGGAAAACTTCAGAAGTGCACT
CCACACTTCATTCATTGCATCAGGCCCAATAACTCAAAGCTGCCAGATACTTTTGATAATTTTTACGTGTCTGCTCAGCTACAATATATT
GGGGTCCTGGAGATGGTGAAGATCTTCCGATATGGATACCCTGTTCGCCTTTCCTTCTCGGATTTCCTGTCAAGGTATAAGCCACTGGCT
GATACATTCCTGCGTGAGAAGAAGGAACAGTCAGCTGCCGAGCGATGTCGACTTGTTCTCCAGCAGTGTAAATTACAAGGCTGGCAGATG
GGAGTCCGAAAAGTGTTTCTAAAATACTGGCATGCTGACCAACTCAATGATTTGTGCCTACAGTTGCAGAGAAAAATTATAACCTGCCAA
AAAGTTATCAGAGGATTTTTAGCACGCCAGCACCTGCTTCAGAGAATAAGCATCAGACAACAAGAGGTGACTTCTATCAATAGCTTTCTG
CAGAACACAGAGGACATGGGGCTGAAAACCTACGATGCCCTGGTCATTCAGAATGCTTCAGACATTGCCCGGGAAAATGACCGGCTCCGT
AGTGAAATGAACGCTCCCTACCATAAAGAGAAGTTAGAGGTCAGGAACATGCAAGAGGAAGGAAGCAAAAGAACCGATGACAAGAGTGGA
CCCAGGCATTTCCACCCCAGCTCCATGTCAGTCTGCGCGGCCGTGGATGGCCTGGGCCAGTGCCTCGTTGGCCCGTCCATCTGGTCTCCT
TCGCTGCACTCGGTGTTCAGCATGGATGACAGCAGCAGCCTCCCGTCTCCACGGAAACAGCCCCCGCCCAAGCCAAAGAGGGACCCCAAC
ACCCGGCTGAGTGCTTCCTATGAGGCTGTGAGCGCCTGCCTCTCCGCGGCCAGGGAAGCGGCCAACGAAGCTCTGGCCCGGCCCAGACCG
CACAGCGACGACTACAGCACCATGAAGAAGATTCCTCCTCGAAAGCCCAAGCGCAGCCCCAACACCAAGCTCAGCGGCTCCTACGAGGAG
ATATCGGGGTCCCGGCCCGGGGACGCGAGGCCCGCGGGCGCCCCGGGGGCAGCAGCGCGCGTTCTGACCCCCGGGACTCCGCAGTGCGCG
CTGCCCCCGGCGGCGCCTCCGGGTGACGAGGACGACAGCGAGCCTGTGTACATCGAGATGCTGGGGCACGCGGCCAGGCCCGATAGCCCG
GACCCCGGGGAGTCCGTGTACGAGGAGATGAAGTGTTGCCTGCCCGACGACGGCGGCCCGGGCGCGGGCTCCTTCCTGCTCCACGGCGCA
TCGCCGCCCCTGCTCCACCGCGCGCCGGAGGACGAGGCGGCGGGGCCCCCAGGGGACGCGTGCGACATCCCGCCGCCCTTCCCCAACCTG
CTGCCGCACCGGCCGCCCCTGCTGGTGTTCCCCCCGACCCCCGTCACCTGCTCCCCCGCCTCCGACGAGTCGCCCCTGACACCCCTGGAG
GTGAAGAAGCTGCCAGTCCTGGAGACCAACCTCAAGTACCCCGTGCAGCCGGAGGGGTCGAGCCCGCTGTCCCCGCAGTACTCCAAGAGC
CAGAAGGGCGACGGCGACAGGCCCGCGTCCCCCGGCCTGGCGCTGTTCAACGGGTCCGGCCGAGCCTCCCCGCCGTCCACGCCGCCCCCG
CCCCCGCCCCCGCCCGGGCCGCCCCCCGCGCCCTACAGGCCCTGCGCGCACTTGGCCTTCCCGCCGGAGCCCGCCCCGGTGAACGCGGGG
AAAGCGGGGCCGAGCGCAGAGGCGCCCAAGGTTCACCCAAAGCCAAACTCTGCCCCCGTGGCCGGGCCCTGCAGCTCCTTCCCCAAGATC
CCATATTCCCCCGTGAAGGCCACCAGGGCGGACGCCAGGAAGGCCGGCTCCAGTGCCTCGCCCCCCGCGCCCTACAGCCCTCCCAGCTCC
AGGCCTCTCAGCAGCCCCCTGGACGAGCTCGCCAGCCTCTTCAACTCGGGGAGGAGTGTGCTTCGGAAATCCGCGGCGGGAAGAAAAATC
AGGGAAGCAGAAGGTTTTGAAACTAACATGAACATAAGTAGCCGAGATGACCCTAGTACGTCAGAAATTACTTCCGAGACTCAAGACAGA
AATGCAAATAACCATGGAATTCAGTTATCTAATTCACTATCTAGTGCTATAACTGCTGAAAATGGAAATTCCATCTCAAATGGTTTACCT
GAAGAAGATGGATACTCACGGTTGTCTATAAGTGGCACAGGGACTTCGACATTTCAAAGACACAGGGACAGTCACACCACTCAGGTAATC
CATCAGCTGAGGCTCTCAGAGAATGAAAGTGTGGCCCTGCAGGAACTCTTGGACTGGAGGAGAAAGCTCTGTGAGGAAGGACAAGACTGG
CAGCAGATCCTGCACCACGCTGAGCCCAGGGTGCCTCCCCCACCACCTTGCAAGAAGCCCAGCCTTCTGAAGAAGCCGGAAGGGGCCTCC
TGCAACAGGCTGCCGTCTGAGCTCTGGGACACCACCATTTGATGTGGCCTGAACTGCAGACTTACAAAATAGAACTGCCTACTGATTCCG
GGCTGCAACAACAGAAGGCTGCCTTCTGACATGCGCTGGGGCTTCTCTCCACGCATTTAGACAAAAAAAGCACAGGACACAGACACTAAA
TATATGAGATCCCGTGTGTGTGTGTGTGTGTTTGTGTGTGTGTGTGTGGGTTCTTTCTTATCCATCTCGTGGTGATACACTCTGATTTTC
AAGCTCCTCATTTACGGCTCTGTGCTACCCCTAGGTAGCAAGAGAGAGGCTGGGAAAAGTGTGGACGTGGCCAGAGCGAGAGAGTAGCGG
AGGAAAGGAGCAATCCATGCACACTCTGTACAGTTGTTTTTCTACGGTTCAACAGTCTGTTTATTGTACTTCCAATGGTTTTATTATAAT
ACAGTATACGGGACATATATTTTATTTCTTTGTAGCTACTTGTGTTTTATTGGTATTATAAACCTGATAATTATTTACATGTTTATTACT
GTAATTTTATAAATTTATGCAATTGGTGGTGCTTCCTTTCTTCAAAATACAGATTTTAAAAAATCATTTCTAGATTATTTTTTTCCTCCA
CAGTCCTTTTTTTTCACCTAACGCACCTAAATCTTGAAACTACATTGTTGTTTTAGCTTCGCCAGTGTCACCCCTTGCAAAACTATGAAT
TGAGCCCCATGTTTTAGGTGTTACTCATGGATGAGGAGGCTGTTCTTTCCTATGCCCTGTATTTCTGGATAAGTGGATTGTGTACCCTTT
AGTTAAATTTCACCTCCCGACTTCAGCATAGATCACAGGAAATCACATGGCACACGGTTAAACACGTATGGCTTCAAATCCATAGCCGGT
GGTGTAAAATGATCATATTCATTCAAAGGCCTACACAGTACAAATGAGCACGCTGCCATGTACTGGTTTGAGCAGTAGGGGCTGCATCGC
ACAGCGCTCGTCCCCCGGGACTTACACTGCATGATTCCCTCACTGTATATCCTCAACCCTCCCATAATGCAAGGCCTTGTTCATTGATGT
GCTTTCGTCGGCTGTCGGAAAGTTCTGAGCAGTGGCTCCAGACCACCTTGTCTTGCTACTTGGAACTTTTTATTCATACCAGCCTTTGAA

>53744_53744_3_MIPEP-MYO16_MIPEP_chr13_24380089_ENST00000382172_MYO16_chr13_109507791_ENST00000357550_length(amino acids)=2110AA_BP=646
MLPWKRGARAPSESSRAGICVGGRDCSGARMLCVGRLGGLGARAAALPPRRAGRGSLEAGIRARRVSTSWSPVGAAFNVKPQGSRLDLFG
ERRGLFGVPELSAPEGFHIAQEKALRKTELLVDRACSTPPGPQTVLIFDELSDSLCRVADLADFVKIAHPEPAFREAAEEACRSIGTMVE
KLNTNVDLYQSLQKLLADKKLVDSLDPETRRVAELFMFDFEISGIHLDKEKRKRAVDLNVKILDLSSTFLMGTNFPNKIEKHLLPEHIRR
NFTSAGDHIIIDGLHAESPDDLVREAAYKIFLYPNAGQLKCLEELLSSRDLLAKLVGYSTFSHRALQGTIAKNPETVMQFLEKLSDKLSE
RTLKDFEMIRGMKMKLNPQNSEVMPWDPPYYSGVIRAERYNIEPSLYCPFFSLGACMEGLNILLNRLLGISLYAEQPAKGEVWSEDVRKL
AVVHESEGLLGYIYCDFFQRADKPHQDCHFTIRGGRLKEDGDYQLPVVVLMLNLPRSSRSSPTLLTPSMMENLFHEMGHAMHSMLGRTRY
QHVTGTRCPTDFAEVPSILMEYFANDYRVVNQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQLQVFYATLDQIYHGKHPLRNSTTDIL
KETQEKFYGLPYVPNTVKLMPPAPNDDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSGKLCSS
LPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRATLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFE
LQFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREKLAVLKRA
LNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRD
LLAKSLYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMETA
YSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGA
IEKNKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKKKGTSTFLQRL
ERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTF
LREKKEQSAAERCRLVLQQCKLQGWQMGVRKVFLKYWHADQLNDLCLQLQRKIITCQKVIRGFLARQHLLQRISIRQQEVTSINSFLQNT
EDMGLKTYDALVIQNASDIARENDRLRSEMNAPYHKEKLEVRNMQEEGSKRTDDKSGPRHFHPSSMSVCAAVDGLGQCLVGPSIWSPSLH
SVFSMDDSSSLPSPRKQPPPKPKRDPNTRLSASYEAVSACLSAAREAANEALARPRPHSDDYSTMKKIPPRKPKRSPNTKLSGSYEEISG
SRPGDARPAGAPGAAARVLTPGTPQCALPPAAPPGDEDDSEPVYIEMLGHAARPDSPDPGESVYEEMKCCLPDDGGPGAGSFLLHGASPP
LLHRAPEDEAAGPPGDACDIPPPFPNLLPHRPPLLVFPPTPVTCSPASDESPLTPLEVKKLPVLETNLKYPVQPEGSSPLSPQYSKSQKG
DGDRPASPGLALFNGSGRASPPSTPPPPPPPPGPPPAPYRPCAHLAFPPEPAPVNAGKAGPSAEAPKVHPKPNSAPVAGPCSSFPKIPYS
PVKATRADARKAGSSASPPAPYSPPSSRPLSSPLDELASLFNSGRSVLRKSAAGRKIREAEGFETNMNISSRDDPSTSEITSETQDRNAN
NHGIQLSNSLSSAITAENGNSISNGLPEEDGYSRLSISGTGTSTFQRHRDSHTTQVIHQLRLSENESVALQELLDWRRKLCEEGQDWQQI

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Fusion Gene PPI Analysis for MIPEP-MYO16


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MIPEP-MYO16


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MIPEP-MYO16


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource