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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MIPOL1-TTC6 (FusionGDB2 ID:53769)

Fusion Gene Summary for MIPOL1-TTC6

check button Fusion gene summary
Fusion gene informationFusion gene name: MIPOL1-TTC6
Fusion gene ID: 53769
HgeneTgene
Gene symbol

MIPOL1

TTC6

Gene ID

145282

319089

Gene namemirror-image polydactyly 1tetratricopeptide repeat domain 6
SynonymsCCDC193C14orf25|NCRNA00291
Cytomap

14q13.3-q21.1

14q21.1

Type of geneprotein-codingprotein-coding
Descriptionmirror-image polydactyly gene 1 proteintetratricopeptide repeat protein 6TPR repeat protein 6
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000327441, ENST00000396294, 
ENST00000537471, ENST00000539062, 
ENST00000545536, ENST00000556451, 
ENST00000536774, ENST00000539174, 
ENST00000267368, ENST00000476979, 
ENST00000382320, ENST00000554555, 
ENST00000553443, 
Fusion gene scores* DoF score21 X 15 X 10=315012 X 14 X 5=840
# samples 2212
** MAII scorelog2(22/3150*10)=-3.83977639974998
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/840*10)=-2.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MIPOL1 [Title/Abstract] AND TTC6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTTC6(38075947)-MIPOL1(37969113), # samples:14
MIPOL1(37717112)-TTC6(38261469), # samples:1
MIPOL1(37717112)-TTC6(38259922), # samples:1
MIPOL1(37717112)-TTC6(38264475), # samples:1
Anticipated loss of major functional domain due to fusion event.MIPOL1-TTC6 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
TTC6-MIPOL1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MIPOL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TTC6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-VQ-A8P3-01AMIPOL1chr14

37717112

+TTC6chr14

38259922

+
ChimerDB4STADTCGA-VQ-A8P3-01AMIPOL1chr14

37717112

+TTC6chr14

38261469

+
ChimerDB4STADTCGA-VQ-A8P3-01AMIPOL1chr14

37717112

+TTC6chr14

38264475

+


Top

Fusion Gene ORF analysis for MIPOL1-TTC6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000327441ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5CDS-5UTRENST00000327441ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5CDS-5UTRENST00000396294ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5CDS-5UTRENST00000396294ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5CDS-5UTRENST00000537471ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5CDS-5UTRENST00000537471ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5CDS-intronENST00000327441ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000327441ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000327441ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000327441ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000327441ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5CDS-intronENST00000327441ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000327441ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000327441ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000327441ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000327441ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5CDS-intronENST00000396294ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000396294ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000396294ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000396294ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000396294ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5CDS-intronENST00000396294ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000396294ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000396294ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000396294ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000396294ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5CDS-intronENST00000537471ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000537471ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000537471ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000537471ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000537471ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5CDS-intronENST00000537471ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000537471ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000537471ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5CDS-intronENST00000537471ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5CDS-intronENST00000537471ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-3CDSENST00000539062ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-3CDSENST00000539062ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-3CDSENST00000539062ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-3CDSENST00000545536ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-3CDSENST00000545536ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-3CDSENST00000545536ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-3CDSENST00000556451ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-3CDSENST00000556451ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-3CDSENST00000556451ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-5UTRENST00000539062ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-5UTRENST00000539062ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-5UTRENST00000545536ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-5UTRENST00000545536ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-5UTRENST00000556451ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-5UTRENST00000556451ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-intronENST00000539062ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000539062ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000539062ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000539062ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000539062ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-intronENST00000539062ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000539062ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000539062ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000539062ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000539062ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-intronENST00000545536ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000545536ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000545536ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000545536ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000545536ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-intronENST00000545536ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000545536ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000545536ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000545536ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000545536ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-intronENST00000556451ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000556451ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000556451ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000556451ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000556451ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38264475

+
5UTR-intronENST00000556451ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000556451ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000556451ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38259922

+
5UTR-intronENST00000556451ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38261469

+
5UTR-intronENST00000556451ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38264475

+
Frame-shiftENST00000327441ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38261469

+
Frame-shiftENST00000327441ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38264475

+
Frame-shiftENST00000396294ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38261469

+
Frame-shiftENST00000396294ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38264475

+
Frame-shiftENST00000537471ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38261469

+
Frame-shiftENST00000537471ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38264475

+
In-frameENST00000327441ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38259922

+
In-frameENST00000396294ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38259922

+
In-frameENST00000537471ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38259922

+
intron-3CDSENST00000536774ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38259922

+
intron-3CDSENST00000536774ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38261469

+
intron-3CDSENST00000536774ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38264475

+
intron-3CDSENST00000539174ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38259922

+
intron-3CDSENST00000539174ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38261469

+
intron-3CDSENST00000539174ENST00000553443MIPOL1chr14

37717112

+TTC6chr14

38264475

+
intron-5UTRENST00000536774ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38264475

+
intron-5UTRENST00000536774ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38264475

+
intron-5UTRENST00000539174ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38264475

+
intron-5UTRENST00000539174ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38264475

+
intron-intronENST00000536774ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38259922

+
intron-intronENST00000536774ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38261469

+
intron-intronENST00000536774ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38259922

+
intron-intronENST00000536774ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38261469

+
intron-intronENST00000536774ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38264475

+
intron-intronENST00000536774ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38259922

+
intron-intronENST00000536774ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38261469

+
intron-intronENST00000536774ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38259922

+
intron-intronENST00000536774ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38261469

+
intron-intronENST00000536774ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38264475

+
intron-intronENST00000539174ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38259922

+
intron-intronENST00000539174ENST00000267368MIPOL1chr14

37717112

+TTC6chr14

38261469

+
intron-intronENST00000539174ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38259922

+
intron-intronENST00000539174ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38261469

+
intron-intronENST00000539174ENST00000382320MIPOL1chr14

37717112

+TTC6chr14

38264475

+
intron-intronENST00000539174ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38259922

+
intron-intronENST00000539174ENST00000476979MIPOL1chr14

37717112

+TTC6chr14

38261469

+
intron-intronENST00000539174ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38259922

+
intron-intronENST00000539174ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38261469

+
intron-intronENST00000539174ENST00000554555MIPOL1chr14

37717112

+TTC6chr14

38264475

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000327441MIPOL1chr1437717112+ENST00000553443TTC6chr1438259922+28824853882709773
ENST00000396294MIPOL1chr1437717112+ENST00000553443TTC6chr1438259922+28834863892710773
ENST00000537471MIPOL1chr1437717112+ENST00000553443TTC6chr1438259922+27543572602581773

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000327441ENST00000553443MIPOL1chr1437717112+TTC6chr1438259922+0.0010885290.9989115
ENST00000396294ENST00000553443MIPOL1chr1437717112+TTC6chr1438259922+0.0011770160.998823
ENST00000537471ENST00000553443MIPOL1chr1437717112+TTC6chr1438259922+0.001188790.99881124

Top

Fusion Genomic Features for MIPOL1-TTC6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for MIPOL1-TTC6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:38075947/chr14:37969113)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012101_1380521.0RepeatNote=TPR 2
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012139_1720521.0RepeatNote=TPR 3
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012176_2090521.0RepeatNote=TPR 4
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012210_2430521.0RepeatNote=TPR 5
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012245_2800521.0RepeatNote=TPR 6
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012281_3140521.0RepeatNote=TPR 7
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012320_3470521.0RepeatNote=TPR 8
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012348_3810521.0RepeatNote=TPR 9
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012382_4150521.0RepeatNote=TPR 10
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012416_4490521.0RepeatNote=TPR 11
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012450_4830521.0RepeatNote=TPR 12
TgeneTTC6chr14:37717112chr14:38259922ENST00000267368012484_5170521.0RepeatNote=TPR 13
TgeneTTC6chr14:37717112chr14:38259922ENST0000026736801257_900521.0RepeatNote=TPR 1
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013101_1380521.0RepeatNote=TPR 2
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013139_1720521.0RepeatNote=TPR 3
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013176_2090521.0RepeatNote=TPR 4
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013210_2430521.0RepeatNote=TPR 5
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013245_2800521.0RepeatNote=TPR 6
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013281_3140521.0RepeatNote=TPR 7
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013320_3470521.0RepeatNote=TPR 8
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013348_3810521.0RepeatNote=TPR 9
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013382_4150521.0RepeatNote=TPR 10
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013416_4490521.0RepeatNote=TPR 11
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013450_4830521.0RepeatNote=TPR 12
TgeneTTC6chr14:37717112chr14:38259922ENST00000476979013484_5170521.0RepeatNote=TPR 13
TgeneTTC6chr14:37717112chr14:38259922ENST0000047697901357_900521.0RepeatNote=TPR 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMIPOL1chr14:37717112chr14:38259922ENST00000327441+414107_2126443.0Coiled coilOntology_term=ECO:0000255
HgeneMIPOL1chr14:37717112chr14:38259922ENST00000327441+414253_4356443.0Coiled coilOntology_term=ECO:0000255
HgeneMIPOL1chr14:37717112chr14:38259922ENST00000396294+515107_2126443.0Coiled coilOntology_term=ECO:0000255
HgeneMIPOL1chr14:37717112chr14:38259922ENST00000396294+515253_4356443.0Coiled coilOntology_term=ECO:0000255
HgeneMIPOL1chr14:37717112chr14:38259922ENST00000536774+18107_2120262.0Coiled coilOntology_term=ECO:0000255
HgeneMIPOL1chr14:37717112chr14:38259922ENST00000536774+18253_4350262.0Coiled coilOntology_term=ECO:0000255
HgeneMIPOL1chr14:37717112chr14:38259922ENST00000537471+313107_2126443.0Coiled coilOntology_term=ECO:0000255
HgeneMIPOL1chr14:37717112chr14:38259922ENST00000537471+313253_4356443.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for MIPOL1-TTC6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>53769_53769_1_MIPOL1-TTC6_MIPOL1_chr14_37717112_ENST00000327441_TTC6_chr14_38259922_ENST00000553443_length(transcript)=2882nt_BP=485nt
CGCCCCGCTCCTCCGCCGGATCGTCTGTGGGTGAGTCTCGAGCCAGGAGGCTCTGAGCCAGTGGCGATTGGCTGACGCGGTGGCTGCGCA
CTCGGCCTGAGAAACTCGGCAAGCGCGCAGTGTCGACTCCCCGGTCTATGCCAGGCGCATCTCAGAGTTTGGCTTAGAGATTAAAGCTCC
TTCTATCTTGTGATGCCACCATCGCAAGGTTCTCAAGGTTGTTGTGGGAGAAGAGAAGGCTAAAGGAGCTCATAGAATGCCTTTAATGCT
AATCCAAAAGTAAATGAGAAACTTAGAAAAAGATTGCCAATTCCAAATCAACATATTTAGAGAAAATTGGAAAAGGAGAAGCTTACTACA
GCTTTATTTGAGGACTTTTTAAAGAACGCTGGGTTCTATCTGTGAGCTGCAAATCTTGGAGCAAAAACCAGAGACATTGCCAGAGCAAAC
AAGAACAGAAATACAAATGGAGAACTGGTCAAAAGCACTCATAAATGATGGCTATGAGAATCTTGGTTGTTTTCTACATCGGGGAATAGT
CTATGCACATCTAAAACTTTGGCTGCTGGCAATTTGTGACTTTGAAACTGTCATTTCTCTAGAAAGAACTATTACTTTGGCTTATGTAAA
TATTGGCCTCATACATCTGCTACACCTGGATAACTACACGGAAGCTATTTGGCAATTTTCTGAGGCTATTAGAATTGATCCTTTATGTAT
TCAAAGCTATCTTTGTCGGGCGGAAACCTATTTTAAGTTGCATAAATTGAAAAAGGCAGTAAATGAATTGTCTCGTGCTATCCACCTTCA
GCCAGATGGAATCCAATTATACATAAGAAGAGGACAATATCTTCTTATGATGAAATATTATGATCTTGCAAAGTTTACTATTTATCAAAT
AGCAGAAATGGACAAAGGTCTCAGTGAGTTGAGTCCTATGCAGCAAGCCCTTATTTATTCATTTTGTGAAAACCATGACAAGGCCATTGA
GGTCTTGGACGGAATCAGCTGGAATAGAGCTGAGATGACCATGTGTGCTCTATTAGCAAAAGTTCAAATGAAGGCCAAGAGAACCAAGGA
AGCTGTGGAAGTGCTTAAGAAGGCTTTGGATGCCATTTCTCATTCTGATAAAGGACCAGATGCCACAGCAATTTCAGCAGACTGTCTGTA
TAACTTGGGTCTTTGTTACATGGAGGAAGGCAATTTACAAATGGCTTTTGATTCTTTTACAAAAGCTGTGAAAGCAAATCCAGATTTTGC
AGAAAGCTTTTATCAGCGAGGGCTTTGTAAAGTGAAACTCCACAAGGATAGCTCGATTCTGGATTTTAATCGTGCAATTACCCTCAATCC
AAAACATTACCAGGCATATTTAAGCCGAGTAGCATTCTATGGTTTAAAAGGCAGGTATTCCAAAGCAATCTTGAATTGTAACAAGGCTAT
TAAAATTTACCCTGAAAGCGTACGTGCCTATCTCTACAGAGGAGTTCTGAAATACTACAACAAGACTTATAAGCTAGCAATTACAGATTT
AACTACAGCTATCAGCATGGACAAAAATAGTTATACAGCATTTTATAACAGAGCATTATGTTACACCAAGATAAGGGAACTTCAAATGGC
ATTAACAGATTATGGAATTGTGCTGCTTCTTGATGCTACAGAAACTGTAAAACTAAATACCTTCCTTAATCGTGGACTCATCTACGTAGA
ACTAGGCCAGTATGGCTTTGCACTAGAGGATTTTAAACAAGCTGCACTGATAAGCCGGACTAACGGGAGCCTTTGTCACGCCACTGCCAT
GTGCCATCACAGAATTAATGAGTTTGAAGAAGCTGTCAATTTCTTTACTTGGGCTCTTAAAATTAACCCATGTTTTCTGGATGCTTATGT
TGGACGGGGAAATTCTTACATGGAATACGGTCATGATGAAGCCACCAAGCAAGCACAGAAAGACTTTCTGAAAGCACTGCATATTAATCC
AGCATACATAAAAGCCAGAATTAGTTTTGGCTATAATTTGCAGGCCCAAGGAAAATTCCAGAAAGCTTGGAACCACTTTACCATTGCCAT
AGATACTGATCCAAAGAACTACCTAGCCTATGAAGGAAGAGCTGTGGTCTGTCTTCAGATGGGTAATAATTTTGCTGCAATGCAGGATAT
TAATGCTGCCATGAAGATCAGTACTACAGCAGAATTCTTAACAAATCGTGGGGTGATTCATGAGTTTATGGGCCACAAACAGAATGCAAT
GAAAGACTACCAAGATGCAATTACTCTAAACCCCAAGTACTCGCTGGCTTACTTTAATGCAGGAAATATCTACTTTCACCACAGGCAGTT
TTCCCAGGCCAGTGACTACTTCTCAAAAGCTTTAAAATTTGATCCAGAAAATGAATATGTTCTCATGAATCGAGCTATTACAAATACAAT
ATTAAAGAAATATGAAGAAGCAAAAGAAGATTTTGCAAATGTAATTGAAAGCTGTCCCTTTTGGGCTGCAGTATATTTTAATAGAGCACA
TTTCTACTACTGCTTAAAGCAATATGAACTAGCTGAGGAAGACCTTAATAAAGCCCTGTCTTTGAAGCCTAATGATGCTCTAGTATATAA
TTTTAGAGCAAAAGTTCGTGGTAAAATAGGTCTGATTGAGGAAGCTATGGCTGACTATAACCAAGCACTTGATCTTGAAGACTATGCCTC
AGTTATATGATTACATAGACTGTGGTTGCTATAGTAGTTTACACAGCTGTTCTCTCTGAAACGGAAACATATTTGTTGTCTAAAAGGTTC
TACCATTTTCATTATTGTATTCGTTATGCTTAGTCTTCCATATAACCTTCTATGCATTTTAATAAAATGTTTGTTATACATTAATTATAA

>53769_53769_1_MIPOL1-TTC6_MIPOL1_chr14_37717112_ENST00000327441_TTC6_chr14_38259922_ENST00000553443_length(amino acids)=773AA_BP=32
MGSICELQILEQKPETLPEQTRTEIQMENWSKALINDGYENLGCFLHRGIVYAHLKLWLLAICDFETVISLERTITLAYVNIGLIHLLHL
DNYTEAIWQFSEAIRIDPLCIQSYLCRAETYFKLHKLKKAVNELSRAIHLQPDGIQLYIRRGQYLLMMKYYDLAKFTIYQIAEMDKGLSE
LSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEE
GNLQMAFDSFTKAVKANPDFAESFYQRGLCKVKLHKDSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRA
YLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALE
DFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISF
GYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITL
NPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYE

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>53769_53769_2_MIPOL1-TTC6_MIPOL1_chr14_37717112_ENST00000396294_TTC6_chr14_38259922_ENST00000553443_length(transcript)=2883nt_BP=486nt
TGCCAGGCGCATCTCAGGAACGAGGTCTCACTATATTGCCCAGACTGGTCTCGAACTCCTGGGCTCAAACAGTCCCCCTGCGTTGGCCTC
CCAAAGTGATGGAATTACAGGTGTGAATCACTGCATCTGACTATGGCAAGGATCTCTGTCACTGAGAGTTTGGCTTAGAGATTAAAGCTC
CTTCTATCTTGTGATGCCACCATCGCAAGGTTCTCAAGGTTGTTGTGGGAGAAGAGAAGGCTAAAGGAGCTCATAGAATGCCTTTAATGC
TAATCCAAAAGTAAATGAGAAACTTAGAAAAAGATTGCCAATTCCAAATCAACATATTTAGAGAAAATTGGAAAAGGAGAAGCTTACTAC
AGCTTTATTTGAGGACTTTTTAAAGAACGCTGGGTTCTATCTGTGAGCTGCAAATCTTGGAGCAAAAACCAGAGACATTGCCAGAGCAAA
CAAGAACAGAAATACAAATGGAGAACTGGTCAAAAGCACTCATAAATGATGGCTATGAGAATCTTGGTTGTTTTCTACATCGGGGAATAG
TCTATGCACATCTAAAACTTTGGCTGCTGGCAATTTGTGACTTTGAAACTGTCATTTCTCTAGAAAGAACTATTACTTTGGCTTATGTAA
ATATTGGCCTCATACATCTGCTACACCTGGATAACTACACGGAAGCTATTTGGCAATTTTCTGAGGCTATTAGAATTGATCCTTTATGTA
TTCAAAGCTATCTTTGTCGGGCGGAAACCTATTTTAAGTTGCATAAATTGAAAAAGGCAGTAAATGAATTGTCTCGTGCTATCCACCTTC
AGCCAGATGGAATCCAATTATACATAAGAAGAGGACAATATCTTCTTATGATGAAATATTATGATCTTGCAAAGTTTACTATTTATCAAA
TAGCAGAAATGGACAAAGGTCTCAGTGAGTTGAGTCCTATGCAGCAAGCCCTTATTTATTCATTTTGTGAAAACCATGACAAGGCCATTG
AGGTCTTGGACGGAATCAGCTGGAATAGAGCTGAGATGACCATGTGTGCTCTATTAGCAAAAGTTCAAATGAAGGCCAAGAGAACCAAGG
AAGCTGTGGAAGTGCTTAAGAAGGCTTTGGATGCCATTTCTCATTCTGATAAAGGACCAGATGCCACAGCAATTTCAGCAGACTGTCTGT
ATAACTTGGGTCTTTGTTACATGGAGGAAGGCAATTTACAAATGGCTTTTGATTCTTTTACAAAAGCTGTGAAAGCAAATCCAGATTTTG
CAGAAAGCTTTTATCAGCGAGGGCTTTGTAAAGTGAAACTCCACAAGGATAGCTCGATTCTGGATTTTAATCGTGCAATTACCCTCAATC
CAAAACATTACCAGGCATATTTAAGCCGAGTAGCATTCTATGGTTTAAAAGGCAGGTATTCCAAAGCAATCTTGAATTGTAACAAGGCTA
TTAAAATTTACCCTGAAAGCGTACGTGCCTATCTCTACAGAGGAGTTCTGAAATACTACAACAAGACTTATAAGCTAGCAATTACAGATT
TAACTACAGCTATCAGCATGGACAAAAATAGTTATACAGCATTTTATAACAGAGCATTATGTTACACCAAGATAAGGGAACTTCAAATGG
CATTAACAGATTATGGAATTGTGCTGCTTCTTGATGCTACAGAAACTGTAAAACTAAATACCTTCCTTAATCGTGGACTCATCTACGTAG
AACTAGGCCAGTATGGCTTTGCACTAGAGGATTTTAAACAAGCTGCACTGATAAGCCGGACTAACGGGAGCCTTTGTCACGCCACTGCCA
TGTGCCATCACAGAATTAATGAGTTTGAAGAAGCTGTCAATTTCTTTACTTGGGCTCTTAAAATTAACCCATGTTTTCTGGATGCTTATG
TTGGACGGGGAAATTCTTACATGGAATACGGTCATGATGAAGCCACCAAGCAAGCACAGAAAGACTTTCTGAAAGCACTGCATATTAATC
CAGCATACATAAAAGCCAGAATTAGTTTTGGCTATAATTTGCAGGCCCAAGGAAAATTCCAGAAAGCTTGGAACCACTTTACCATTGCCA
TAGATACTGATCCAAAGAACTACCTAGCCTATGAAGGAAGAGCTGTGGTCTGTCTTCAGATGGGTAATAATTTTGCTGCAATGCAGGATA
TTAATGCTGCCATGAAGATCAGTACTACAGCAGAATTCTTAACAAATCGTGGGGTGATTCATGAGTTTATGGGCCACAAACAGAATGCAA
TGAAAGACTACCAAGATGCAATTACTCTAAACCCCAAGTACTCGCTGGCTTACTTTAATGCAGGAAATATCTACTTTCACCACAGGCAGT
TTTCCCAGGCCAGTGACTACTTCTCAAAAGCTTTAAAATTTGATCCAGAAAATGAATATGTTCTCATGAATCGAGCTATTACAAATACAA
TATTAAAGAAATATGAAGAAGCAAAAGAAGATTTTGCAAATGTAATTGAAAGCTGTCCCTTTTGGGCTGCAGTATATTTTAATAGAGCAC
ATTTCTACTACTGCTTAAAGCAATATGAACTAGCTGAGGAAGACCTTAATAAAGCCCTGTCTTTGAAGCCTAATGATGCTCTAGTATATA
ATTTTAGAGCAAAAGTTCGTGGTAAAATAGGTCTGATTGAGGAAGCTATGGCTGACTATAACCAAGCACTTGATCTTGAAGACTATGCCT
CAGTTATATGATTACATAGACTGTGGTTGCTATAGTAGTTTACACAGCTGTTCTCTCTGAAACGGAAACATATTTGTTGTCTAAAAGGTT
CTACCATTTTCATTATTGTATTCGTTATGCTTAGTCTTCCATATAACCTTCTATGCATTTTAATAAAATGTTTGTTATACATTAATTATA

>53769_53769_2_MIPOL1-TTC6_MIPOL1_chr14_37717112_ENST00000396294_TTC6_chr14_38259922_ENST00000553443_length(amino acids)=773AA_BP=32
MGSICELQILEQKPETLPEQTRTEIQMENWSKALINDGYENLGCFLHRGIVYAHLKLWLLAICDFETVISLERTITLAYVNIGLIHLLHL
DNYTEAIWQFSEAIRIDPLCIQSYLCRAETYFKLHKLKKAVNELSRAIHLQPDGIQLYIRRGQYLLMMKYYDLAKFTIYQIAEMDKGLSE
LSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEE
GNLQMAFDSFTKAVKANPDFAESFYQRGLCKVKLHKDSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRA
YLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALE
DFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISF
GYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITL
NPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYE

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>53769_53769_3_MIPOL1-TTC6_MIPOL1_chr14_37717112_ENST00000537471_TTC6_chr14_38259922_ENST00000553443_length(transcript)=2754nt_BP=357nt
GGAACGAGGTCTCACTATATTGCCCAGACTGGTCTCGAACTCCTGGGCTCAAACAGTCCCCCTGCGTTGGCCTCCCAAAGTGATGGAATT
ACAGGTGTGAATCACTGCATCTGACTATGGCAAGGATCTCTGTCACTGAGCTAATCCAAAAGTAAATGAGAAACTTAGAAAAAGATTGCC
AATTCCAAATCAACATATTTAGAGAAAATTGGAAAAGGAGAAGCTTACTACAGCTTTATTTGAGGACTTTTTAAAGAACGCTGGGTTCTA
TCTGTGAGCTGCAAATCTTGGAGCAAAAACCAGAGACATTGCCAGAGCAAACAAGAACAGAAATACAAATGGAGAACTGGTCAAAAGCAC
TCATAAATGATGGCTATGAGAATCTTGGTTGTTTTCTACATCGGGGAATAGTCTATGCACATCTAAAACTTTGGCTGCTGGCAATTTGTG
ACTTTGAAACTGTCATTTCTCTAGAAAGAACTATTACTTTGGCTTATGTAAATATTGGCCTCATACATCTGCTACACCTGGATAACTACA
CGGAAGCTATTTGGCAATTTTCTGAGGCTATTAGAATTGATCCTTTATGTATTCAAAGCTATCTTTGTCGGGCGGAAACCTATTTTAAGT
TGCATAAATTGAAAAAGGCAGTAAATGAATTGTCTCGTGCTATCCACCTTCAGCCAGATGGAATCCAATTATACATAAGAAGAGGACAAT
ATCTTCTTATGATGAAATATTATGATCTTGCAAAGTTTACTATTTATCAAATAGCAGAAATGGACAAAGGTCTCAGTGAGTTGAGTCCTA
TGCAGCAAGCCCTTATTTATTCATTTTGTGAAAACCATGACAAGGCCATTGAGGTCTTGGACGGAATCAGCTGGAATAGAGCTGAGATGA
CCATGTGTGCTCTATTAGCAAAAGTTCAAATGAAGGCCAAGAGAACCAAGGAAGCTGTGGAAGTGCTTAAGAAGGCTTTGGATGCCATTT
CTCATTCTGATAAAGGACCAGATGCCACAGCAATTTCAGCAGACTGTCTGTATAACTTGGGTCTTTGTTACATGGAGGAAGGCAATTTAC
AAATGGCTTTTGATTCTTTTACAAAAGCTGTGAAAGCAAATCCAGATTTTGCAGAAAGCTTTTATCAGCGAGGGCTTTGTAAAGTGAAAC
TCCACAAGGATAGCTCGATTCTGGATTTTAATCGTGCAATTACCCTCAATCCAAAACATTACCAGGCATATTTAAGCCGAGTAGCATTCT
ATGGTTTAAAAGGCAGGTATTCCAAAGCAATCTTGAATTGTAACAAGGCTATTAAAATTTACCCTGAAAGCGTACGTGCCTATCTCTACA
GAGGAGTTCTGAAATACTACAACAAGACTTATAAGCTAGCAATTACAGATTTAACTACAGCTATCAGCATGGACAAAAATAGTTATACAG
CATTTTATAACAGAGCATTATGTTACACCAAGATAAGGGAACTTCAAATGGCATTAACAGATTATGGAATTGTGCTGCTTCTTGATGCTA
CAGAAACTGTAAAACTAAATACCTTCCTTAATCGTGGACTCATCTACGTAGAACTAGGCCAGTATGGCTTTGCACTAGAGGATTTTAAAC
AAGCTGCACTGATAAGCCGGACTAACGGGAGCCTTTGTCACGCCACTGCCATGTGCCATCACAGAATTAATGAGTTTGAAGAAGCTGTCA
ATTTCTTTACTTGGGCTCTTAAAATTAACCCATGTTTTCTGGATGCTTATGTTGGACGGGGAAATTCTTACATGGAATACGGTCATGATG
AAGCCACCAAGCAAGCACAGAAAGACTTTCTGAAAGCACTGCATATTAATCCAGCATACATAAAAGCCAGAATTAGTTTTGGCTATAATT
TGCAGGCCCAAGGAAAATTCCAGAAAGCTTGGAACCACTTTACCATTGCCATAGATACTGATCCAAAGAACTACCTAGCCTATGAAGGAA
GAGCTGTGGTCTGTCTTCAGATGGGTAATAATTTTGCTGCAATGCAGGATATTAATGCTGCCATGAAGATCAGTACTACAGCAGAATTCT
TAACAAATCGTGGGGTGATTCATGAGTTTATGGGCCACAAACAGAATGCAATGAAAGACTACCAAGATGCAATTACTCTAAACCCCAAGT
ACTCGCTGGCTTACTTTAATGCAGGAAATATCTACTTTCACCACAGGCAGTTTTCCCAGGCCAGTGACTACTTCTCAAAAGCTTTAAAAT
TTGATCCAGAAAATGAATATGTTCTCATGAATCGAGCTATTACAAATACAATATTAAAGAAATATGAAGAAGCAAAAGAAGATTTTGCAA
ATGTAATTGAAAGCTGTCCCTTTTGGGCTGCAGTATATTTTAATAGAGCACATTTCTACTACTGCTTAAAGCAATATGAACTAGCTGAGG
AAGACCTTAATAAAGCCCTGTCTTTGAAGCCTAATGATGCTCTAGTATATAATTTTAGAGCAAAAGTTCGTGGTAAAATAGGTCTGATTG
AGGAAGCTATGGCTGACTATAACCAAGCACTTGATCTTGAAGACTATGCCTCAGTTATATGATTACATAGACTGTGGTTGCTATAGTAGT
TTACACAGCTGTTCTCTCTGAAACGGAAACATATTTGTTGTCTAAAAGGTTCTACCATTTTCATTATTGTATTCGTTATGCTTAGTCTTC

>53769_53769_3_MIPOL1-TTC6_MIPOL1_chr14_37717112_ENST00000537471_TTC6_chr14_38259922_ENST00000553443_length(amino acids)=773AA_BP=32
MGSICELQILEQKPETLPEQTRTEIQMENWSKALINDGYENLGCFLHRGIVYAHLKLWLLAICDFETVISLERTITLAYVNIGLIHLLHL
DNYTEAIWQFSEAIRIDPLCIQSYLCRAETYFKLHKLKKAVNELSRAIHLQPDGIQLYIRRGQYLLMMKYYDLAKFTIYQIAEMDKGLSE
LSPMQQALIYSFCENHDKAIEVLDGISWNRAEMTMCALLAKVQMKAKRTKEAVEVLKKALDAISHSDKGPDATAISADCLYNLGLCYMEE
GNLQMAFDSFTKAVKANPDFAESFYQRGLCKVKLHKDSSILDFNRAITLNPKHYQAYLSRVAFYGLKGRYSKAILNCNKAIKIYPESVRA
YLYRGVLKYYNKTYKLAITDLTTAISMDKNSYTAFYNRALCYTKIRELQMALTDYGIVLLLDATETVKLNTFLNRGLIYVELGQYGFALE
DFKQAALISRTNGSLCHATAMCHHRINEFEEAVNFFTWALKINPCFLDAYVGRGNSYMEYGHDEATKQAQKDFLKALHINPAYIKARISF
GYNLQAQGKFQKAWNHFTIAIDTDPKNYLAYEGRAVVCLQMGNNFAAMQDINAAMKISTTAEFLTNRGVIHEFMGHKQNAMKDYQDAITL
NPKYSLAYFNAGNIYFHHRQFSQASDYFSKALKFDPENEYVLMNRAITNTILKKYEEAKEDFANVIESCPFWAAVYFNRAHFYYCLKQYE

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Fusion Gene PPI Analysis for MIPOL1-TTC6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MIPOL1-TTC6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MIPOL1-TTC6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource