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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MKLN1-IMMP2L (FusionGDB2 ID:54085)

Fusion Gene Summary for MKLN1-IMMP2L

check button Fusion gene summary
Fusion gene informationFusion gene name: MKLN1-IMMP2L
Fusion gene ID: 54085
HgeneTgene
Gene symbol

MKLN1

IMMP2L

Gene ID

4289

83943

Gene namemuskelin 1inner mitochondrial membrane peptidase subunit 2
SynonymsTWA2IMMP2L-IT1|IMP2|IMP2-LIKE
Cytomap

7q32.3

7q31.1

Type of geneprotein-codingprotein-coding
Descriptionmuskelinmuskelin 1, intracellular mediator containing kelch motifsmitochondrial inner membrane protease subunit 2IMP2 inner mitochondrial membrane peptidase-likeIMP2 inner mitochondrial membrane protease-likeinner mitochondrial membrane peptidase 2 like
Modification date2020031320200313
UniProtAcc.

Q96T52

Ensembl transtripts involved in fusion geneENST00000352689, ENST00000421797, 
ENST00000429546, ENST00000498778, 
ENST00000450877, ENST00000489381, 
ENST00000437687, ENST00000447215, 
ENST00000405709, ENST00000331762, 
ENST00000415362, ENST00000452895, 
Fusion gene scores* DoF score15 X 15 X 7=157529 X 19 X 14=7714
# samples 1632
** MAII scorelog2(16/1575*10)=-3.29920801838728
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(32/7714*10)=-4.5913353357414
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MKLN1 [Title/Abstract] AND IMMP2L [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMKLN1(131130662)-IMMP2L(110303777), # samples:1
Anticipated loss of major functional domain due to fusion event.MKLN1-IMMP2L seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MKLN1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across IMMP2L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-38-4631-01AMKLN1chr7

131130662

-IMMP2Lchr7

110303777

-


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Fusion Gene ORF analysis for MKLN1-IMMP2L

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000352689ENST00000450877MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
5CDS-5UTRENST00000352689ENST00000489381MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
5CDS-5UTRENST00000421797ENST00000450877MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
5CDS-5UTRENST00000421797ENST00000489381MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
5CDS-intronENST00000352689ENST00000437687MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
5CDS-intronENST00000352689ENST00000447215MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
5CDS-intronENST00000421797ENST00000437687MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
5CDS-intronENST00000421797ENST00000447215MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
Frame-shiftENST00000352689ENST00000405709MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
Frame-shiftENST00000421797ENST00000405709MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
In-frameENST00000352689ENST00000331762MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
In-frameENST00000352689ENST00000415362MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
In-frameENST00000352689ENST00000452895MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
In-frameENST00000421797ENST00000331762MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
In-frameENST00000421797ENST00000415362MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
In-frameENST00000421797ENST00000452895MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-3CDSENST00000429546ENST00000331762MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-3CDSENST00000429546ENST00000405709MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-3CDSENST00000429546ENST00000415362MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-3CDSENST00000429546ENST00000452895MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-3CDSENST00000498778ENST00000331762MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-3CDSENST00000498778ENST00000405709MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-3CDSENST00000498778ENST00000415362MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-3CDSENST00000498778ENST00000452895MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-5UTRENST00000429546ENST00000450877MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-5UTRENST00000429546ENST00000489381MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-5UTRENST00000498778ENST00000450877MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-5UTRENST00000498778ENST00000489381MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-intronENST00000429546ENST00000437687MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-intronENST00000429546ENST00000447215MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-intronENST00000498778ENST00000437687MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-
intron-intronENST00000498778ENST00000447215MKLN1chr7

131130662

-IMMP2Lchr7

110303777

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000421797MKLN1chr7131130662-ENST00000331762IMMP2Lchr7110303777-232916612051788527
ENST00000421797MKLN1chr7131130662-ENST00000452895IMMP2Lchr7110303777-196716612051788527
ENST00000421797MKLN1chr7131130662-ENST00000415362IMMP2Lchr7110303777-178116612051779525
ENST00000352689MKLN1chr7131130662-ENST00000331762IMMP2Lchr7110303777-2233156511692563
ENST00000352689MKLN1chr7131130662-ENST00000452895IMMP2Lchr7110303777-1871156511692563
ENST00000352689MKLN1chr7131130662-ENST00000415362IMMP2Lchr7110303777-1685156511683561

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000421797ENST00000331762MKLN1chr7131130662-IMMP2Lchr7110303777-0.0002188350.9997812
ENST00000421797ENST00000452895MKLN1chr7131130662-IMMP2Lchr7110303777-0.0003647560.9996352
ENST00000421797ENST00000415362MKLN1chr7131130662-IMMP2Lchr7110303777-0.53048410.46951592
ENST00000352689ENST00000331762MKLN1chr7131130662-IMMP2Lchr7110303777-0.0001445690.9998554
ENST00000352689ENST00000452895MKLN1chr7131130662-IMMP2Lchr7110303777-0.0002518660.9997482
ENST00000352689ENST00000415362MKLN1chr7131130662-IMMP2Lchr7110303777-0.527429940.47257003

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Fusion Genomic Features for MKLN1-IMMP2L


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MKLN1-IMMP2L


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:131130662/chr7:110303777)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.IMMP2L

Q96T52

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO. {ECO:0000269|PubMed:15814844}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMKLN1chr7:131130662chr7:110303777ENST00000352689-1218172_204508736.0DomainLisH
HgeneMKLN1chr7:131130662chr7:110303777ENST00000352689-1218206_258508736.0DomainCTLH
HgeneMKLN1chr7:131130662chr7:110303777ENST00000352689-1218284_330508736.0RepeatNote=Kelch 1
HgeneMKLN1chr7:131130662chr7:110303777ENST00000352689-1218339_391508736.0RepeatNote=Kelch 2
HgeneMKLN1chr7:131130662chr7:110303777ENST00000352689-1218408_458508736.0RepeatNote=Kelch 3
TgeneIMMP2Lchr7:131130662chr7:110303777ENST000004376870419_370111.0TransmembraneHelical
TgeneIMMP2Lchr7:131130662chr7:110303777ENST000004472150519_370111.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMKLN1chr7:131130662chr7:110303777ENST00000352689-1218469_515508736.0RepeatNote=Kelch 4
HgeneMKLN1chr7:131130662chr7:110303777ENST00000352689-1218526_578508736.0RepeatNote=Kelch 5
HgeneMKLN1chr7:131130662chr7:110303777ENST00000352689-1218597_651508736.0RepeatNote=Kelch 6
TgeneIMMP2Lchr7:131130662chr7:110303777ENST000003317625719_37136176.0TransmembraneHelical
TgeneIMMP2Lchr7:131130662chr7:110303777ENST000004057094619_37136176.0TransmembraneHelical
TgeneIMMP2Lchr7:131130662chr7:110303777ENST000004153623519_37136176.0TransmembraneHelical
TgeneIMMP2Lchr7:131130662chr7:110303777ENST000004528955719_37136176.0TransmembraneHelical


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Fusion Gene Sequence for MKLN1-IMMP2L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>54085_54085_1_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000352689_IMMP2L_chr7_110303777_ENST00000331762_length(transcript)=2233nt_BP=1565nt
GCTGCCAGCGGTCGGTGGCGGCCGCTACGGTGCTGACAAGATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCC
CTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTACCTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATG
GTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGA
GAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAA
GAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTT
GTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTG
GTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCA
AAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGA
GTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAA
AAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTT
GTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACAC
TGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTT
GGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGA
TACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAG
AATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAAC
CTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAA
TCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACAT
AATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGC
GCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGTACAGAGAGAAGAGGAATGACTGCATGAATCTACCTGAGTTGCTG
GCATTGGGAGGCCAGTTACTGGAAAGGAATGGAAAAAAGAAGCCTCCAAAAGGGAAAAACTTCTGACAATATGATGCTGTGCGAGAAATA
TTTACAGCACATTAAAACGATCTGTATTATTAAATAAATAATTTTCAAATGTTAAACAGTATTAAATGGCACCTGATTTTGTGTTAAATT
TTAGTTCCCTGTTGTTTAATGCCCCCAAAATATGCAGACCTTTGGGAATATAAAAATATTGCACCCACATGTCTTAATGGGGCTGAATTT
CAGATTATTTGTTACATATACTTATTATATTGATTGTTGGGTTTTGATTTTGGTGCTTGCTGCTGAAATAAATTGAAAATTAATATTCAA
TAAAAATGATGTATTTGTCACTTGCTGTTAAGGTAGAACAAGAAGGAACACATATTATACACATAATGATGGGAATTACATTGTGATTTG

>54085_54085_1_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000352689_IMMP2L_chr7_110303777_ENST00000331762_length(amino acids)=563AA_BP=521
LPAVGGGRYGADKMAAGGAVAAAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYE
KTHVCNLKKFKVFGGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNW
YSKYREQEAIRLCLKHFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPK
STKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYL
DSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQT
WKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMGFPRTSACPCHTYPVAPRA

--------------------------------------------------------------
>54085_54085_2_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000352689_IMMP2L_chr7_110303777_ENST00000415362_length(transcript)=1685nt_BP=1565nt
GCTGCCAGCGGTCGGTGGCGGCCGCTACGGTGCTGACAAGATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCC
CTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTACCTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATG
GTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGA
GAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAA
GAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTT
GTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTG
GTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCA
AAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGA
GTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAA
AAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTT
GTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACAC
TGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTT
GGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGA
TACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAG
AATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAAC
CTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAA
TCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACAT
AATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGC

>54085_54085_2_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000352689_IMMP2L_chr7_110303777_ENST00000415362_length(amino acids)=561AA_BP=521
LPAVGGGRYGADKMAAGGAVAAAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYE
KTHVCNLKKFKVFGGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNW
YSKYREQEAIRLCLKHFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPK
STKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYL
DSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQT
WKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMGFPRTSACPCHTYPVAPRA

--------------------------------------------------------------
>54085_54085_3_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000352689_IMMP2L_chr7_110303777_ENST00000452895_length(transcript)=1871nt_BP=1565nt
GCTGCCAGCGGTCGGTGGCGGCCGCTACGGTGCTGACAAGATGGCGGCTGGCGGAGCTGTCGCTGCGGCGCCCGAGTGCCGGCTTCTCCC
CTACGCGCTACACAAGTGGAGCTCCTTTTCCTCCACCTACCTTCCCGAGAACATTTTAGTGGACAAACCAAATGACCAATCTTCAAGATG
GTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAAATATGA
GAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGGCTTAAA
GAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCCACTCTT
GTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCTCAACTG
GTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTCACTGCA
AAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTGCGAAGA
GTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCATTCCCAA
AAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGTTTATTT
GTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAGAGACAC
TGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCGTTACTT
GGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAGTGAGGA
TACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGGTGGTAG
AATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATGTCAAAC
CTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTCAAAAAA
TCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGTAGACAT
AATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCCCAGAGC
GCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGTACAGAGAGAAGAGGAATGACTGCATGAATCTACCTGAGTTGCTG
GCATTGGGAGGCCAGTTACTGGAAAGGAATGGAAAAAAGAAGCCTCCAAAAGGGAAAAACTTCTGACAATATGATGCTGTGCGAGAAATA

>54085_54085_3_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000352689_IMMP2L_chr7_110303777_ENST00000452895_length(amino acids)=563AA_BP=521
LPAVGGGRYGADKMAAGGAVAAAPECRLLPYALHKWSSFSSTYLPENILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYE
KTHVCNLKKFKVFGGMNEENMTELLSSGLKNDYNKETFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNW
YSKYREQEAIRLCLKHFRQHNYTEAFESLQKKTKIALEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPK
STKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDGTQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYL
DSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGGPKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQT
WKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVFGGQRSKTYLNDFFSYDVDSDHVDIISDGTKKDSGMGFPRTSACPCHTYPVAPRA

--------------------------------------------------------------
>54085_54085_4_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000421797_IMMP2L_chr7_110303777_ENST00000331762_length(transcript)=2329nt_BP=1661nt
AACCTGATCCTCCGGTAGCGAAGGGCTAGAGGCAAACACCGAGCTCCTCCAGAGCCGCCCGGGAGCAGGGAGGGCTCCGCTAGCCCGGGG
GGCCCTCCCCGCGGGGCAGATGAGTTCCATATCCAGACTCTCAAACCATGTTTTGGGATCATCCAAACATTCCATCCTCCTGACTCCATA
AACTATTGGATTCATAACCTGCTCCATGCTTGAAAACATGGGGATTGGAATTCGGAACATTTTAGTGGACAAACCAAATGACCAATCTTC
AAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAA
ATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGG
CTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCC
ACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCT
CAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTC
ACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTG
CGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCAT
TCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGT
TTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAG
AGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCG
TTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAG
TGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGG
TGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATG
TCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTC
AAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGT
AGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCC
CAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGTACAGAGAGAAGAGGAATGACTGCATGAATCTACCTGAG
TTGCTGGCATTGGGAGGCCAGTTACTGGAAAGGAATGGAAAAAAGAAGCCTCCAAAAGGGAAAAACTTCTGACAATATGATGCTGTGCGA
GAAATATTTACAGCACATTAAAACGATCTGTATTATTAAATAAATAATTTTCAAATGTTAAACAGTATTAAATGGCACCTGATTTTGTGT
TAAATTTTAGTTCCCTGTTGTTTAATGCCCCCAAAATATGCAGACCTTTGGGAATATAAAAATATTGCACCCACATGTCTTAATGGGGCT
GAATTTCAGATTATTTGTTACATATACTTATTATATTGATTGTTGGGTTTTGATTTTGGTGCTTGCTGCTGAAATAAATTGAAAATTAAT
ATTCAATAAAAATGATGTATTTGTCACTTGCTGTTAAGGTAGAACAAGAAGGAACACATATTATACACATAATGATGGGAATTACATTGT

>54085_54085_4_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000421797_IMMP2L_chr7_110303777_ENST00000331762_length(amino acids)=527AA_BP=485
MLENMGIGIRNILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVFGGMNEENMTELLSSGLKNDYNKE
TFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLKHFRQHNYTEAFESLQKKTKIA
LEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDG
TQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGG
PKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVF

--------------------------------------------------------------
>54085_54085_5_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000421797_IMMP2L_chr7_110303777_ENST00000415362_length(transcript)=1781nt_BP=1661nt
AACCTGATCCTCCGGTAGCGAAGGGCTAGAGGCAAACACCGAGCTCCTCCAGAGCCGCCCGGGAGCAGGGAGGGCTCCGCTAGCCCGGGG
GGCCCTCCCCGCGGGGCAGATGAGTTCCATATCCAGACTCTCAAACCATGTTTTGGGATCATCCAAACATTCCATCCTCCTGACTCCATA
AACTATTGGATTCATAACCTGCTCCATGCTTGAAAACATGGGGATTGGAATTCGGAACATTTTAGTGGACAAACCAAATGACCAATCTTC
AAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAA
ATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGG
CTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCC
ACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCT
CAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTC
ACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTG
CGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCAT
TCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGT
TTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAG
AGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCG
TTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAG
TGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGG
TGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATG
TCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTC
AAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGT
AGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCC

>54085_54085_5_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000421797_IMMP2L_chr7_110303777_ENST00000415362_length(amino acids)=525AA_BP=485
MLENMGIGIRNILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVFGGMNEENMTELLSSGLKNDYNKE
TFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLKHFRQHNYTEAFESLQKKTKIA
LEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDG
TQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGG
PKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVF

--------------------------------------------------------------
>54085_54085_6_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000421797_IMMP2L_chr7_110303777_ENST00000452895_length(transcript)=1967nt_BP=1661nt
AACCTGATCCTCCGGTAGCGAAGGGCTAGAGGCAAACACCGAGCTCCTCCAGAGCCGCCCGGGAGCAGGGAGGGCTCCGCTAGCCCGGGG
GGCCCTCCCCGCGGGGCAGATGAGTTCCATATCCAGACTCTCAAACCATGTTTTGGGATCATCCAAACATTCCATCCTCCTGACTCCATA
AACTATTGGATTCATAACCTGCTCCATGCTTGAAAACATGGGGATTGGAATTCGGAACATTTTAGTGGACAAACCAAATGACCAATCTTC
AAGATGGTCTTCAGAGAGCAACTATCCTCCCCAGTACTTGATTCTAAAGCTCGAAAGGCCTGCTATAGTTCAGAATATCACATTTGGAAA
ATATGAGAAAACTCATGTTTGCAATTTGAAGAAATTTAAAGTCTTTGGTGGAATGAATGAAGAAAATATGACAGAGCTGTTGTCCAGTGG
CTTAAAGAATGATTATAACAAAGAAACATTCACCTTGAAGCATAAAATTGATGAACAGATGTTCCCTTGTCGATTCATTAAAATAGTTCC
ACTCTTGTCCTGGGGACCCAGCTTTAACTTTAGCATCTGGTATGTTGAACTTAGTGGCATTGATGATCCTGATATAGTACAACCTTGTCT
CAACTGGTATAGCAAGTACCGTGAACAGGAAGCTATTCGCCTTTGCCTAAAACACTTCAGACAACACAACTATACAGAAGCTTTTGAGTC
ACTGCAAAAGAAAACCAAGATTGCACTGGAACATCCCATGTTAACAGATATTCATGACAAGCTGGTGTTGAAGGGTGATTTTGATGCTTG
CGAAGAGTTGATTGAAAAGGCTGTAAATGATGGCTTGTTCAATCAGTATATCAGTCAACAGGAATATAAGCCACGATGGAGTCAAATCAT
TCCCAAAAGTACCAAAGGTGATGGGGAAGATAACCGTCCAGGAATGAGAGGAGGCCATCAGATGGTTATTGATGTTCAAACAGAGACTGT
TTATTTGTTTGGTGGCTGGGATGGAACACAAGATCTTGCTGACTTCTGGGCGTACAGTGTGAAGGAGAACCAGTGGACATGTATCTCTAG
AGACACTGAAAAAGAGAATGGTCCTAGTGCCAGATCGTGTCATAAAATGTGCATTGATATTCAACGGAGGCAAATCTACACATTGGGGCG
TTACTTGGATTCCTCTGTGAGGAACAGCAAATCTCTGAAAAGTGACTTCTATCGTTATGACATTGATACAAACACATGGATGTTACTAAG
TGAGGATACTGCTGCTGATGGAGGGCCGAAATTGGTGTTTGATCATCAGATGTGTATGGACTCAGAAAAACATATGATCTACACTTTTGG
TGGTAGAATTTTGACTTGTAATGGCAGCGTAGATGACAGCAGAGCCAGTGAACCACAATTCAGTGGCTTGTTTGCTTTCAACTGTCAATG
TCAAACCTGGAAACTTCTTCGAGAGGACTCCTGTAATGCTGGGCCTGAGGACATCCAGTCTCGAATAGGACACTGCATGTTATTCCACTC
AAAAAATCGTTGCTTATATGTATTTGGTGGCCAGCGATCAAAGACCTATTTGAATGATTTCTTTAGTTATGATGTGGACTCTGATCATGT
AGACATAATATCAGATGGCACCAAGAAAGACTCTGGGATGGGTTTCCCTAGGACTTCTGCATGCCCATGCCACACATATCCTGTGGCCCC
CAGAGCGCTGGCAGAAATTGGAATCTGTTCTTCCTCCAGAGCGCTTACCAGTACAGAGAGAAGAGGAATGACTGCATGAATCTACCTGAG
TTGCTGGCATTGGGAGGCCAGTTACTGGAAAGGAATGGAAAAAAGAAGCCTCCAAAAGGGAAAAACTTCTGACAATATGATGCTGTGCGA

>54085_54085_6_MKLN1-IMMP2L_MKLN1_chr7_131130662_ENST00000421797_IMMP2L_chr7_110303777_ENST00000452895_length(amino acids)=527AA_BP=485
MLENMGIGIRNILVDKPNDQSSRWSSESNYPPQYLILKLERPAIVQNITFGKYEKTHVCNLKKFKVFGGMNEENMTELLSSGLKNDYNKE
TFTLKHKIDEQMFPCRFIKIVPLLSWGPSFNFSIWYVELSGIDDPDIVQPCLNWYSKYREQEAIRLCLKHFRQHNYTEAFESLQKKTKIA
LEHPMLTDIHDKLVLKGDFDACEELIEKAVNDGLFNQYISQQEYKPRWSQIIPKSTKGDGEDNRPGMRGGHQMVIDVQTETVYLFGGWDG
TQDLADFWAYSVKENQWTCISRDTEKENGPSARSCHKMCIDIQRRQIYTLGRYLDSSVRNSKSLKSDFYRYDIDTNTWMLLSEDTAADGG
PKLVFDHQMCMDSEKHMIYTFGGRILTCNGSVDDSRASEPQFSGLFAFNCQCQTWKLLREDSCNAGPEDIQSRIGHCMLFHSKNRCLYVF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MKLN1-IMMP2L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MKLN1-IMMP2L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MKLN1-IMMP2L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource