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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MMP2-DYNC1LI2 (FusionGDB2 ID:54428)

Fusion Gene Summary for MMP2-DYNC1LI2

check button Fusion gene summary
Fusion gene informationFusion gene name: MMP2-DYNC1LI2
Fusion gene ID: 54428
HgeneTgene
Gene symbol

MMP2

DYNC1LI2

Gene ID

4313

1783

Gene namematrix metallopeptidase 2dynein cytoplasmic 1 light intermediate chain 2
SynonymsCLG4|CLG4A|MMP-2|MMP-II|MONA|TBE-1DNCLI2|LIC2
Cytomap

16q12.2

16q22.1

Type of geneprotein-codingprotein-coding
Description72 kDa type IV collagenasecollagenase type IV-Amatrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)matrix metalloproteinase-2matrix metalloproteinase-IIneutrophil gelatinasecytoplasmic dynein 1 light intermediate chain 2LIC-2LIC53/55dynein light intermediate chain 2, cytosolicdynein, cytoplasmic, light intermediate polypeptide 2
Modification date2020032920200313
UniProtAcc

P08253

O43237

Ensembl transtripts involved in fusion geneENST00000219070, ENST00000437642, 
ENST00000543485, ENST00000570308, 
ENST00000440564, ENST00000570201, 
ENST00000258198, ENST00000379482, 
ENST00000443351, 
Fusion gene scores* DoF score8 X 8 X 2=1287 X 6 X 6=252
# samples 88
** MAII scorelog2(8/128*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/252*10)=-1.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MMP2 [Title/Abstract] AND DYNC1LI2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMMP2(55536800)-DYNC1LI2(66770147), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMMP2

GO:0006508

proteolysis

15863497


check buttonFusion gene breakpoints across MMP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DYNC1LI2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-8530MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-


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Fusion Gene ORF analysis for MMP2-DYNC1LI2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000219070ENST00000440564MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
5CDS-intronENST00000219070ENST00000570201MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
5CDS-intronENST00000437642ENST00000440564MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
5CDS-intronENST00000437642ENST00000570201MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
5CDS-intronENST00000543485ENST00000440564MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
5CDS-intronENST00000543485ENST00000570201MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
5CDS-intronENST00000570308ENST00000440564MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
5CDS-intronENST00000570308ENST00000570201MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000219070ENST00000258198MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000219070ENST00000379482MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000219070ENST00000443351MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000437642ENST00000258198MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000437642ENST00000379482MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000437642ENST00000443351MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000543485ENST00000258198MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000543485ENST00000379482MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000543485ENST00000443351MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000570308ENST00000258198MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000570308ENST00000379482MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-
In-frameENST00000570308ENST00000443351MMP2chr16

55536800

+DYNC1LI2chr16

66770147

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000570308MMP2chr1655536800+ENST00000258198DYNC1LI2chr1666770147-611523365353285916
ENST00000570308MMP2chr1655536800+ENST00000379482DYNC1LI2chr1666770147-243723365352436634
ENST00000570308MMP2chr1655536800+ENST00000443351DYNC1LI2chr1666770147-353023365353285916
ENST00000219070MMP2chr1655536800+ENST00000258198DYNC1LI2chr1666770147-616723885093337942
ENST00000219070MMP2chr1655536800+ENST00000379482DYNC1LI2chr1666770147-248923885092488660
ENST00000219070MMP2chr1655536800+ENST00000443351DYNC1LI2chr1666770147-358223885093337942
ENST00000543485MMP2chr1655536800+ENST00000258198DYNC1LI2chr1666770147-55701791712740889
ENST00000543485MMP2chr1655536800+ENST00000379482DYNC1LI2chr1666770147-18921791711891607
ENST00000543485MMP2chr1655536800+ENST00000443351DYNC1LI2chr1666770147-29851791712740889
ENST00000437642MMP2chr1655536800+ENST00000258198DYNC1LI2chr1666770147-582720483192997892
ENST00000437642MMP2chr1655536800+ENST00000379482DYNC1LI2chr1666770147-214920483192148610
ENST00000437642MMP2chr1655536800+ENST00000443351DYNC1LI2chr1666770147-324220483192997892

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000570308ENST00000258198MMP2chr1655536800+DYNC1LI2chr1666770147-0.000184720.9998153
ENST00000570308ENST00000379482MMP2chr1655536800+DYNC1LI2chr1666770147-0.0039279040.99607205
ENST00000570308ENST00000443351MMP2chr1655536800+DYNC1LI2chr1666770147-0.0011735820.99882644
ENST00000219070ENST00000258198MMP2chr1655536800+DYNC1LI2chr1666770147-0.0001814530.9998186
ENST00000219070ENST00000379482MMP2chr1655536800+DYNC1LI2chr1666770147-0.0060512980.9939487
ENST00000219070ENST00000443351MMP2chr1655536800+DYNC1LI2chr1666770147-0.0012533810.99874663
ENST00000543485ENST00000258198MMP2chr1655536800+DYNC1LI2chr1666770147-0.000238080.9997619
ENST00000543485ENST00000379482MMP2chr1655536800+DYNC1LI2chr1666770147-0.0046165440.99538344
ENST00000543485ENST00000443351MMP2chr1655536800+DYNC1LI2chr1666770147-0.0016928350.9983071
ENST00000437642ENST00000258198MMP2chr1655536800+DYNC1LI2chr1666770147-0.000166120.9998338
ENST00000437642ENST00000379482MMP2chr1655536800+DYNC1LI2chr1666770147-0.003799340.9962006
ENST00000437642ENST00000443351MMP2chr1655536800+DYNC1LI2chr1666770147-0.001257370.99874264

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Fusion Genomic Features for MMP2-DYNC1LI2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MMP2-DYNC1LI2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:55536800/chr16:66770147)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MMP2

P08253

DYNC1LI2

O43237

FUNCTION: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14.; FUNCTION: PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels.; FUNCTION: [Isoform 2]: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213228_276626661.0DomainFibronectin type-II 1
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213286_334626661.0DomainFibronectin type-II 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213344_392626661.0DomainFibronectin type-II 3
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213228_276576611.0DomainFibronectin type-II 1
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213286_334576611.0DomainFibronectin type-II 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213344_392576611.0DomainFibronectin type-II 3
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213228_276550585.0DomainFibronectin type-II 1
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213286_334550585.0DomainFibronectin type-II 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213344_392550585.0DomainFibronectin type-II 3
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314228_276550585.0DomainFibronectin type-II 1
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314286_334550585.0DomainFibronectin type-II 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314344_392550585.0DomainFibronectin type-II 3
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213100_107626661.0MotifCysteine switch
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213100_107576611.0MotifCysteine switch
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213100_107550585.0MotifCysteine switch
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314100_107550585.0MotifCysteine switch
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213110_221626661.0RegionNote=Collagenase-like 1
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213222_396626661.0RegionNote=Collagen-binding
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213397_465626661.0RegionNote=Collagenase-like 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213110_221576611.0RegionNote=Collagenase-like 1
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213222_396576611.0RegionNote=Collagen-binding
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213397_465576611.0RegionNote=Collagenase-like 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213110_221550585.0RegionNote=Collagenase-like 1
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213222_396550585.0RegionNote=Collagen-binding
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213397_465550585.0RegionNote=Collagenase-like 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314110_221550585.0RegionNote=Collagenase-like 1
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314222_396550585.0RegionNote=Collagen-binding
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314397_465550585.0RegionNote=Collagenase-like 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213472_516626661.0RepeatNote=Hemopexin 1
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213517_563626661.0RepeatNote=Hemopexin 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213565_613626661.0RepeatNote=Hemopexin 3
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213472_516576611.0RepeatNote=Hemopexin 1
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213517_563576611.0RepeatNote=Hemopexin 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213472_516550585.0RepeatNote=Hemopexin 1
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314472_516550585.0RepeatNote=Hemopexin 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213414_660626661.0RegionRequired for inhibitor TIMP2 binding
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213414_660576611.0RegionRequired for inhibitor TIMP2 binding
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213414_660550585.0RegionRequired for inhibitor TIMP2 binding
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314414_660550585.0RegionRequired for inhibitor TIMP2 binding
HgeneMMP2chr16:55536800chr16:66770147ENST00000219070+1213614_660626661.0RepeatNote=Hemopexin 4
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213565_613576611.0RepeatNote=Hemopexin 3
HgeneMMP2chr16:55536800chr16:66770147ENST00000437642+1213614_660576611.0RepeatNote=Hemopexin 4
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213517_563550585.0RepeatNote=Hemopexin 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213565_613550585.0RepeatNote=Hemopexin 3
HgeneMMP2chr16:55536800chr16:66770147ENST00000543485+1213614_660550585.0RepeatNote=Hemopexin 4
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314517_563550585.0RepeatNote=Hemopexin 2
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314565_613550585.0RepeatNote=Hemopexin 3
HgeneMMP2chr16:55536800chr16:66770147ENST00000570308+1314614_660550585.0RepeatNote=Hemopexin 4
TgeneDYNC1LI2chr16:55536800chr16:66770147ENST0000025819831361_68176493.0Nucleotide bindingATP


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Fusion Gene Sequence for MMP2-DYNC1LI2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>54428_54428_1_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000219070_DYNC1LI2_chr16_66770147_ENST00000258198_length(transcript)=6167nt_BP=2388nt
TGGGGTGACGAGGTCGTGCACTGAGGGTGGACGTAGAGGCCAGGAGTAGCAGGCGGCCGGGGAAAAGAGGTGGAGAAAGGAAAAAAGAGG
AGAAAAGTGGAGGAGGGCGAGTAGGGGGGTGGGGCAGAGAGGGGCGGGCCCGAGTGCGCCCCCCGCCCCCAGCCCCGCTCTGCCAGCTCC
CTCCCAGCCCAGCCGGCTACATCTGGCGGCTGCCCTCCCTTGTTTCCGCTGCATCCAGACTTCCTCAGGCGGTGGCTGGAGGCTGCGCAT
CTGGGGCTTTAAACATACAAAGGGATTGCCAGGACCTGCGGCGGCGGCGGCGGCGGCGGGGGCTGGGGCGCGGGGGCCGGACCATGAGCC
GCTGAGCCGGGCAAACCCCAGGCCACCGAGCCAGCGGACCCTCGGAGCGCAGCCCTGCGCCGCGGAGCAGGCTCCAACCAGGCGGCGAGG
CGGCCACACGCACCGAGCCAGCGACCCCCGGGCGACGCGCGGGGCCAGGGAGCGCTACGATGGAGGCGCTAATGGCCCGGGGCGCGCTCA
CGGGTCCCCTGAGGGCGCTCTGTCTCCTGGGCTGCCTGCTGAGCCACGCCGCCGCCGCGCCGTCGCCCATCATCAAGTTCCCCGGCGATG
TCGCCCCCAAAACGGACAAAGAGTTGGCAGTGCAATACCTGAACACCTTCTATGGCTGCCCCAAGGAGAGCTGCAACCTGTTTGTGCTGA
AGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGATCTTGACCAGAATACCATCGAGACCATGCGGAAGCCAC
GCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAAGTGGGACAAGAACCAGATCACATACAGGATCATTGGCT
ACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTTCCAAGTCTGGAGCGATGTGACCCCACTGCGGTTTTCTC
GAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCATGGCGATGGATACCCCTTTGACGGTAAGGACGGACTCC
TGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGATGACGATGAGCTATGGACCTTGGGAGAAGGCCAAGTGG
TCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTTGTTCAATGGCAAGGAGTACAACAGCTGCACTGATACCG
GCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGATGGCAAGTACGGCTTCTGTCCCCATGAAGCCCTGTTCA
CCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCAGGGCACATCCTATGACAGCTGCACCACTGAGGGCCGCA
CGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAAGTATGGCTTCTGCCCTGAGACCGCCATGTCCACTGTTG
GTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAACAAATATGAGAGCTGCACCAGCGCCGGCCGCAGTGACG
GAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGGCTTCTGCCCTGACCAAGGGTACAGCCTGTTCCTCGTGG
CAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGGGGCCCTGATGGCACCCATTTACACCTACACCAAGAACT
TCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTCTCCTGACATTGACCTTGGCACCGGCCCCACCCCCACGC
TGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCATCGCTCAGATCCGTGGTGAGATCTTCTTCTTCAAGGACC
GGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCTGGTGGCCACATTCTGGCCTGAGCTCCCGGAAAAGATTG
ATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAATGAATACTGGATCTACTCAGCCAGCACCCTGGAGCGAG
GGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGTGGATGCCGCCTTTAACTGGAGCAAAAACAAGAAGACAT
ACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAATGGATCCTGGCTTCCCCAAGCTCATCGCAGATGCCTGGA
ATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGTGAAAGATTTTCAAGACTATATGGAACCTGAAGAAGGTT
GTCAAGGTTCCCCACAGAGAAGAGGCCCTCTGACCTCAGGCTCCGATGAAGAAAATGTTGCCCTGCCTCTGGGTGACAATGTGCTGACTC
ATAACCTGGGGATCCCGGTGTTGGTGGTGTGCACAAAGTGTGATGCGGTGAGTGTCCTGGAGAAGGAGCACGATTACAGGGATGAGCATT
TGGACTTTATCCAGTCACACCTGCGGAGGTTCTGCCTTCAGTATGGAGCTGCCTTGATTTACACATCAGTGAAAGAAGAGAAAAACCTCG
ACTTGTTGTATAAGTATATTGTTCATAAAACATACGGTTTCCACTTCACCACACCTGCCTTAGTTGTGGAAAAGGATGCCGTTTTTATAC
CTGCAGGCTGGGACAATGAAAAGAAAATAGCTATTTTACATGAAAATTTTACAACCGTGAAGCCGGAAGATGCATATGAAGACTTTATTG
TGAAACCTCCCGTGAGAAAGCTGGTCCACGACAAAGAGTTGGCAGCAGAAGATGAGCAGGTGTTCCTAATGAAGCAACAGTCACTCCTTG
CCAAGCAACCAGCCACTCCCACGAGAGCTTCTGAATCTCCTGCAAGAGGACCCTCTGGCTCTCCAAGGACCCAGGGTCGGGGAGGGCCAG
CCAGTGTGCCTAGCTCCTCCCCAGGCACGTCAGTAAAAAAGCCGGACCCAAACATCAAAAATAATGCAGCAAGTGAAGGGGTGTTGGCCA
GCTTCTTCAACAGTCTGTTGAGTAAAAAGACAGGCTCTCCTGGAAGTCCTGGTGCTGGTGGGGTGCAGAGCACAGCCAAGAAGTCAGGAC
AAAAGACTGTGTTGTCAAATGTTCAGGAAGAACTGGATAGAATGACTCGAAAGCCAGACTCTATGGTAACAAACTCTTCAACAGAAAATG
AAGCCTGAACCTCCTTAAAAAGTGCATATGTCGAATGACCAAATAACTATGTATATTGATCTGCTAAGACCAGGATTTTTCTGATATGGC
ACATGCTATCAGTTTTTTGGGGCAGGGGAGATGAACTTTAAAAAAAAAAAAAAAACTTCATTGGCTTGTCCGAGTGTGAAATGCACATTT
AGGAAGGTTACATGTCAGACCCTTTGTTAAGGATAACCCTTGGACTCTGGGGCATGTGGCTCTTTTGTGGGAGGCAAGCACATCTGGGCT
TCTTGTGGAGGGGAAGGTAGAGTGAAAGAAAGAGGGCCCACTTTCTAACAGGGTGGAGCAAATGAGACCAAGAAATCATTGGTAAGATGA
TGGTTAGTCTGACCAGTTTCATGTTAGTAAATTCACTTGTTCTTGGGAAGCAGATTAAGTAGCAGAAAGTCCAGGAAAGAAAGACCAGAA
GGAGTAATGAGACAAGTGATGGTGGGGAAGCTGAATGTTGAGGGAGGTGGAGGAAGGAGGAGATGAGCAGTGTCAGTAAATACTGTGCAT
TCAGTAGAAGTTGAAGAATCATTGTTAGAAGCATTTCCAAACAAAACACTAAGCAAAATGGGAATTAGGCTTATTTTGAATGCATCTTTA
ACTTACGAAAGATGTACTAATTGTGGGGGTGCCTGAGTCAGGCGGAGCTGACCCAGGGGTGGGAACGATGGCAGCTGCCCAGGACCCATG
TGCTTGGCCCAGGCTATGTCCTCGTGAGAGGTACTGGGGTCCACGGATATGTGTTGTGGGGCAGACAGTCACTGTGGGATGTCTTCAAAG
TCAGCAGTTACAGAATTAGTTTACTTTGAATTTTGTTGTCTAAATAGCTCCTGCTTTATTTTTTAAATTAAATTTTTTGTTTTTACTATC
ACAGGCTGGCCTAACTAATACAAAATAGGTGATGAACCTCTGGTTTTACCATAATGCAATGTGCCACGGAAAGTTTGGGGGAGGTTTTTA
ATGTAATTGCACTCTGGTTAATTGGCTCGTACCAAGCCCTGCCTTATGACTTGTGGAAAGCTTCAAGGAGTTCCACTGATGCAAAAGGGT
CTTTTCCTAGCTTCCTGGTCTGATCAGTGCTATGAGATGGACAGATAAGTGTGAATGTTTTATACAGAAAATGGAAATGATACATTTCTC
TTGTTAGGTGTTTTCATAAAATGTAGCATTTTTTTTCTTATGGAAATAAGAGTTTCAGGTGTCTCCCCACCTAGGGCAAATTCATGCACA
TTGTCATGTTATACCACCATTCTGGAAATGATTTCTGTGGATTTGAAATTGCACTTTTAATTTTATATATGACAGCATTTAAATGCAAAC
ACTACCATGAATTTAATGTATAAAATGTTGTCAAACCAAGGGAAAAAACCACAGTTCACCATGTGGAGTTTACTTTTTTTATATGAATGT
TTGTTGTACTGTGTCTAAGCATAACTTCCCTAATGTCATTACTTTTACATACCAGATTTGACTGACCACTAATGTAGTACTGGGGATAAC
TTAATATCCTATGTTGTGTCAAGACTCTTTGAAGACTTTCTTGAATTGCTTTCGTAAAGGTCTGAACACTGTTAAGGAGAAAGCTGAGTA
TCAACTTGCCTTTCTGATAGAAATGTTTCTTGTGCCAGTTTTATTGTTGAGATATACTATTTTTTTCCTTTTTTAATTCAGTTTTTTAAA
AAAACAAATGTATTGTGGCTTCCAGTTACCAGGTTGTCTAGGTAATGACAGTAAACTGACTGTAGAATGATAATTGTGGTATAGTGACCA
ATAGATGCCAAACAGCTTGTGGCCTCACTAAAGGTGGGGTCGCTTAGTCCCCGGGAGTAAAATGAGTGACCTCAGAAACAAGAATTCCTG
GAAAGGCACATGCCGAAGAGGAATATGGTATAATTTTAAATTTTAATGCAAAATTTTAATTTGTCTTTATTTTTTATCATTTGAACTGAT
AAGCACTTTTTGTGTCAATATAAAATATACTAAAACTGATGAAATGCTAAGACATGTCTTGTGAAGGAAGGTTTCTTGGAGACCACTTTT
ATTTACTCATGAGAAGTGGAAGCTCCTAGTATCAGAAGAAGCTGATACATAGTGTCATGTGCTCAGTGGTTGCCAAAGTCTACCAACTTT
GGGGAGCTGCAGGGTTCTTTTTGGGAGGTGGGAGGAAGGGAGATGAGTTTTGTTATTTTGGGGTTTTCAAGCATTGGAACCAAAGGCCAA
ATAATAAACAGCCTTTAGTTTTTAAAGTAAAATTCATTTTATTTGCAGAGTACACTTGTATGGTAGACTGTTAAAGACAATTTTATGACT
ATTTATGCACATTATAATGGTTACATCTGCTTTTTGTCTTTAAAATAAAAAAAAAAATCAGAGAAAAGCCCACCTTTGAATACGTGGCTG
AAGATAACAGCCAAGAATTGGTCTTTCCTAAAAATGCAACAGATAATGCTGCTAGATTGTTATTTTGTTTGCACTTTTTTTTGATTGGCA
TTTTAAAATCGGTATTTAAACTGAAGACATTGTCATGTTTTATTAATTTAACAAAGTTGAAAGTGACTGCTCTGTACATCATGACCTTAA
CAATGTTAATGCTGTAAGTGAAAGTTCACTGTCGTCTGTATACTAAATTTATTGGTGTTTCTAACTTAAAAGTAAGACTGCAGATTATCC
CCCACCAGCCTTAGTCCAGGGGTGTGGCTCTGTCCGGGTGCAGTATGCAGTCATGTGGAACCTTGCTTTCTAGTCCTGGGAAAAAAAGAT

>54428_54428_1_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000219070_DYNC1LI2_chr16_66770147_ENST00000258198_length(amino acids)=942AA_BP=626
MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD
QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK
YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD
IDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY
WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGVVKD
FQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVVCTKCDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALI
YTSVKEEKNLDLLYKYIVHKTYGFHFTTPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQ
VFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGTSVKKPDPNIKNNAASEGVLASFFNSLLSKKTGSPGSPGAG

--------------------------------------------------------------
>54428_54428_2_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000219070_DYNC1LI2_chr16_66770147_ENST00000379482_length(transcript)=2489nt_BP=2388nt
TGGGGTGACGAGGTCGTGCACTGAGGGTGGACGTAGAGGCCAGGAGTAGCAGGCGGCCGGGGAAAAGAGGTGGAGAAAGGAAAAAAGAGG
AGAAAAGTGGAGGAGGGCGAGTAGGGGGGTGGGGCAGAGAGGGGCGGGCCCGAGTGCGCCCCCCGCCCCCAGCCCCGCTCTGCCAGCTCC
CTCCCAGCCCAGCCGGCTACATCTGGCGGCTGCCCTCCCTTGTTTCCGCTGCATCCAGACTTCCTCAGGCGGTGGCTGGAGGCTGCGCAT
CTGGGGCTTTAAACATACAAAGGGATTGCCAGGACCTGCGGCGGCGGCGGCGGCGGCGGGGGCTGGGGCGCGGGGGCCGGACCATGAGCC
GCTGAGCCGGGCAAACCCCAGGCCACCGAGCCAGCGGACCCTCGGAGCGCAGCCCTGCGCCGCGGAGCAGGCTCCAACCAGGCGGCGAGG
CGGCCACACGCACCGAGCCAGCGACCCCCGGGCGACGCGCGGGGCCAGGGAGCGCTACGATGGAGGCGCTAATGGCCCGGGGCGCGCTCA
CGGGTCCCCTGAGGGCGCTCTGTCTCCTGGGCTGCCTGCTGAGCCACGCCGCCGCCGCGCCGTCGCCCATCATCAAGTTCCCCGGCGATG
TCGCCCCCAAAACGGACAAAGAGTTGGCAGTGCAATACCTGAACACCTTCTATGGCTGCCCCAAGGAGAGCTGCAACCTGTTTGTGCTGA
AGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGATCTTGACCAGAATACCATCGAGACCATGCGGAAGCCAC
GCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAAGTGGGACAAGAACCAGATCACATACAGGATCATTGGCT
ACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTTCCAAGTCTGGAGCGATGTGACCCCACTGCGGTTTTCTC
GAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCATGGCGATGGATACCCCTTTGACGGTAAGGACGGACTCC
TGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGATGACGATGAGCTATGGACCTTGGGAGAAGGCCAAGTGG
TCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTTGTTCAATGGCAAGGAGTACAACAGCTGCACTGATACCG
GCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGATGGCAAGTACGGCTTCTGTCCCCATGAAGCCCTGTTCA
CCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCAGGGCACATCCTATGACAGCTGCACCACTGAGGGCCGCA
CGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAAGTATGGCTTCTGCCCTGAGACCGCCATGTCCACTGTTG
GTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAACAAATATGAGAGCTGCACCAGCGCCGGCCGCAGTGACG
GAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGGCTTCTGCCCTGACCAAGGGTACAGCCTGTTCCTCGTGG
CAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGGGGCCCTGATGGCACCCATTTACACCTACACCAAGAACT
TCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTCTCCTGACATTGACCTTGGCACCGGCCCCACCCCCACGC
TGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCATCGCTCAGATCCGTGGTGAGATCTTCTTCTTCAAGGACC
GGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCTGGTGGCCACATTCTGGCCTGAGCTCCCGGAAAAGATTG
ATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAATGAATACTGGATCTACTCAGCCAGCACCCTGGAGCGAG
GGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGTGGATGCCGCCTTTAACTGGAGCAAAAACAAGAAGACAT
ACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAATGGATCCTGGCTTCCCCAAGCTCATCGCAGATGCCTGGA
ATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGTGAAAGATTTTCAAGACTATATGGAACCTGAAGAAGGTT

>54428_54428_2_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000219070_DYNC1LI2_chr16_66770147_ENST00000379482_length(amino acids)=660AA_BP=626
MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD
QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK
YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD
IDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY
WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGVVKD

--------------------------------------------------------------
>54428_54428_3_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000219070_DYNC1LI2_chr16_66770147_ENST00000443351_length(transcript)=3582nt_BP=2388nt
TGGGGTGACGAGGTCGTGCACTGAGGGTGGACGTAGAGGCCAGGAGTAGCAGGCGGCCGGGGAAAAGAGGTGGAGAAAGGAAAAAAGAGG
AGAAAAGTGGAGGAGGGCGAGTAGGGGGGTGGGGCAGAGAGGGGCGGGCCCGAGTGCGCCCCCCGCCCCCAGCCCCGCTCTGCCAGCTCC
CTCCCAGCCCAGCCGGCTACATCTGGCGGCTGCCCTCCCTTGTTTCCGCTGCATCCAGACTTCCTCAGGCGGTGGCTGGAGGCTGCGCAT
CTGGGGCTTTAAACATACAAAGGGATTGCCAGGACCTGCGGCGGCGGCGGCGGCGGCGGGGGCTGGGGCGCGGGGGCCGGACCATGAGCC
GCTGAGCCGGGCAAACCCCAGGCCACCGAGCCAGCGGACCCTCGGAGCGCAGCCCTGCGCCGCGGAGCAGGCTCCAACCAGGCGGCGAGG
CGGCCACACGCACCGAGCCAGCGACCCCCGGGCGACGCGCGGGGCCAGGGAGCGCTACGATGGAGGCGCTAATGGCCCGGGGCGCGCTCA
CGGGTCCCCTGAGGGCGCTCTGTCTCCTGGGCTGCCTGCTGAGCCACGCCGCCGCCGCGCCGTCGCCCATCATCAAGTTCCCCGGCGATG
TCGCCCCCAAAACGGACAAAGAGTTGGCAGTGCAATACCTGAACACCTTCTATGGCTGCCCCAAGGAGAGCTGCAACCTGTTTGTGCTGA
AGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGATCTTGACCAGAATACCATCGAGACCATGCGGAAGCCAC
GCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAAGTGGGACAAGAACCAGATCACATACAGGATCATTGGCT
ACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTTCCAAGTCTGGAGCGATGTGACCCCACTGCGGTTTTCTC
GAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCATGGCGATGGATACCCCTTTGACGGTAAGGACGGACTCC
TGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGATGACGATGAGCTATGGACCTTGGGAGAAGGCCAAGTGG
TCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTTGTTCAATGGCAAGGAGTACAACAGCTGCACTGATACCG
GCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGATGGCAAGTACGGCTTCTGTCCCCATGAAGCCCTGTTCA
CCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCAGGGCACATCCTATGACAGCTGCACCACTGAGGGCCGCA
CGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAAGTATGGCTTCTGCCCTGAGACCGCCATGTCCACTGTTG
GTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAACAAATATGAGAGCTGCACCAGCGCCGGCCGCAGTGACG
GAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGGCTTCTGCCCTGACCAAGGGTACAGCCTGTTCCTCGTGG
CAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGGGGCCCTGATGGCACCCATTTACACCTACACCAAGAACT
TCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTCTCCTGACATTGACCTTGGCACCGGCCCCACCCCCACGC
TGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCATCGCTCAGATCCGTGGTGAGATCTTCTTCTTCAAGGACC
GGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCTGGTGGCCACATTCTGGCCTGAGCTCCCGGAAAAGATTG
ATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAATGAATACTGGATCTACTCAGCCAGCACCCTGGAGCGAG
GGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGTGGATGCCGCCTTTAACTGGAGCAAAAACAAGAAGACAT
ACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAATGGATCCTGGCTTCCCCAAGCTCATCGCAGATGCCTGGA
ATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGTGAAAGATTTTCAAGACTATATGGAACCTGAAGAAGGTT
GTCAAGGTTCCCCACAGAGAAGAGGCCCTCTGACCTCAGGCTCCGATGAAGAAAATGTTGCCCTGCCTCTGGGTGACAATGTGCTGACTC
ATAACCTGGGGATCCCGGTGTTGGTGGTGTGCACAAAGTGTGATGCGGTGAGTGTCCTGGAGAAGGAGCACGATTACAGGGATGAGCATT
TGGACTTTATCCAGTCACACCTGCGGAGGTTCTGCCTTCAGTATGGAGCTGCCTTGATTTACACATCAGTGAAAGAAGAGAAAAACCTCG
ACTTGTTGTATAAGTATATTGTTCATAAAACATACGGTTTCCACTTCACCACACCTGCCTTAGTTGTGGAAAAGGATGCCGTTTTTATAC
CTGCAGGCTGGGACAATGAAAAGAAAATAGCTATTTTACATGAAAATTTTACAACCGTGAAGCCGGAAGATGCATATGAAGACTTTATTG
TGAAACCTCCCGTGAGAAAGCTGGTCCACGACAAAGAGTTGGCAGCAGAAGATGAGCAGGTGTTCCTAATGAAGCAACAGTCACTCCTTG
CCAAGCAACCAGCCACTCCCACGAGAGCTTCTGAATCTCCTGCAAGAGGACCCTCTGGCTCTCCAAGGACCCAGGGTCGGGGAGGGCCAG
CCAGTGTGCCTAGCTCCTCCCCAGGCACGTCAGTAAAAAAGCCGGACCCAAACATCAAAAATAATGCAGCAAGTGAAGGGGTGTTGGCCA
GCTTCTTCAACAGTCTGTTGAGTAAAAAGACAGGCTCTCCTGGAAGTCCTGGTGCTGGTGGGGTGCAGAGCACAGCCAAGAAGTCAGGAC
AAAAGACTGTGTTGTCAAATGTTCAGGAAGAACTGGATAGAATGACTCGAAAGCCAGACTCTATGGTAACAAACTCTTCAACAGAAAATG
AAGCCTGAACCTCCTTAAAAAGTGCATATGTCGAATGACCAAATAACTATGTATATTGATCTGCTAAGACCAGGATTTTTCTGATATGGC
ACATGCTATCAGTTTTTTGGGGCAGGGGAGATGAACTTTAAAAAAAAAAAAAAAACTTCATTGGCTTGTCCGAGTGTGAAATGCACATTT

>54428_54428_3_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000219070_DYNC1LI2_chr16_66770147_ENST00000443351_length(amino acids)=942AA_BP=626
MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLD
QNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGD
GYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGK
YGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKY
ESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPD
IDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEY
WIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGVVKD
FQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVVCTKCDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALI
YTSVKEEKNLDLLYKYIVHKTYGFHFTTPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQ
VFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGTSVKKPDPNIKNNAASEGVLASFFNSLLSKKTGSPGSPGAG

--------------------------------------------------------------
>54428_54428_4_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000437642_DYNC1LI2_chr16_66770147_ENST00000258198_length(transcript)=5827nt_BP=2048nt
AATGCATGCCTGCCCTCCTGGGAATGAAGCACAGCAGGTCTCAGCCTCATCTTACCCAGCCCCCCACTCAAGATGGAGGTGCCTGGTTTG
AACACCTCTGACAAATGGAAGTCTGTGTTGTCCAGAGGCAATGCAGTGGGGGCTTAAGAAGATAACTCTGGACTTAGACCGCTTGGCTTC
AAATCAAAGAGTGCATGAACCAACCAGCTGGCCTAGTGATGATGTTAGGCAAGTGACTTCTCAGTTTCTTCATCTGCAAACTGGGAAATT
TCCTATCTCAGGGTTAAAAGAGAGGTAATCTTAGGTGCTTACCTAGCACATGCAATACCTGAACACCTTCTATGGCTGCCCCAAGGAGAG
CTGCAACCTGTTTGTGCTGAAGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGATCTTGACCAGAATACCAT
CGAGACCATGCGGAAGCCACGCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAAGTGGGACAAGAACCAGAT
CACATACAGGATCATTGGCTACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTTCCAAGTCTGGAGCGATGT
GACCCCACTGCGGTTTTCTCGAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCATGGCGATGGATACCCCTT
TGACGGTAAGGACGGACTCCTGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGATGACGATGAGCTATGGAC
CTTGGGAGAAGGCCAAGTGGTCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTTGTTCAATGGCAAGGAGTA
CAACAGCTGCACTGATACCGGCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGATGGCAAGTACGGCTTCTG
TCCCCATGAAGCCCTGTTCACCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCAGGGCACATCCTATGACAG
CTGCACCACTGAGGGCCGCACGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAAGTATGGCTTCTGCCCTGA
GACCGCCATGTCCACTGTTGGTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAACAAATATGAGAGCTGCAC
CAGCGCCGGCCGCAGTGACGGAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGGCTTCTGCCCTGACCAAGG
GTACAGCCTGTTCCTCGTGGCAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGGGGCCCTGATGGCACCCAT
TTACACCTACACCAAGAACTTCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTCTCCTGACATTGACCTTGG
CACCGGCCCCACCCCCACGCTGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCATCGCTCAGATCCGTGGTGA
GATCTTCTTCTTCAAGGACCGGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCTGGTGGCCACATTCTGGCC
TGAGCTCCCGGAAAAGATTGATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAATGAATACTGGATCTACTC
AGCCAGCACCCTGGAGCGAGGGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGTGGATGCCGCCTTTAACTG
GAGCAAAAACAAGAAGACATACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAATGGATCCTGGCTTCCCCAA
GCTCATCGCAGATGCCTGGAATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGTGAAAGATTTTCAAGACTA
TATGGAACCTGAAGAAGGTTGTCAAGGTTCCCCACAGAGAAGAGGCCCTCTGACCTCAGGCTCCGATGAAGAAAATGTTGCCCTGCCTCT
GGGTGACAATGTGCTGACTCATAACCTGGGGATCCCGGTGTTGGTGGTGTGCACAAAGTGTGATGCGGTGAGTGTCCTGGAGAAGGAGCA
CGATTACAGGGATGAGCATTTGGACTTTATCCAGTCACACCTGCGGAGGTTCTGCCTTCAGTATGGAGCTGCCTTGATTTACACATCAGT
GAAAGAAGAGAAAAACCTCGACTTGTTGTATAAGTATATTGTTCATAAAACATACGGTTTCCACTTCACCACACCTGCCTTAGTTGTGGA
AAAGGATGCCGTTTTTATACCTGCAGGCTGGGACAATGAAAAGAAAATAGCTATTTTACATGAAAATTTTACAACCGTGAAGCCGGAAGA
TGCATATGAAGACTTTATTGTGAAACCTCCCGTGAGAAAGCTGGTCCACGACAAAGAGTTGGCAGCAGAAGATGAGCAGGTGTTCCTAAT
GAAGCAACAGTCACTCCTTGCCAAGCAACCAGCCACTCCCACGAGAGCTTCTGAATCTCCTGCAAGAGGACCCTCTGGCTCTCCAAGGAC
CCAGGGTCGGGGAGGGCCAGCCAGTGTGCCTAGCTCCTCCCCAGGCACGTCAGTAAAAAAGCCGGACCCAAACATCAAAAATAATGCAGC
AAGTGAAGGGGTGTTGGCCAGCTTCTTCAACAGTCTGTTGAGTAAAAAGACAGGCTCTCCTGGAAGTCCTGGTGCTGGTGGGGTGCAGAG
CACAGCCAAGAAGTCAGGACAAAAGACTGTGTTGTCAAATGTTCAGGAAGAACTGGATAGAATGACTCGAAAGCCAGACTCTATGGTAAC
AAACTCTTCAACAGAAAATGAAGCCTGAACCTCCTTAAAAAGTGCATATGTCGAATGACCAAATAACTATGTATATTGATCTGCTAAGAC
CAGGATTTTTCTGATATGGCACATGCTATCAGTTTTTTGGGGCAGGGGAGATGAACTTTAAAAAAAAAAAAAAAACTTCATTGGCTTGTC
CGAGTGTGAAATGCACATTTAGGAAGGTTACATGTCAGACCCTTTGTTAAGGATAACCCTTGGACTCTGGGGCATGTGGCTCTTTTGTGG
GAGGCAAGCACATCTGGGCTTCTTGTGGAGGGGAAGGTAGAGTGAAAGAAAGAGGGCCCACTTTCTAACAGGGTGGAGCAAATGAGACCA
AGAAATCATTGGTAAGATGATGGTTAGTCTGACCAGTTTCATGTTAGTAAATTCACTTGTTCTTGGGAAGCAGATTAAGTAGCAGAAAGT
CCAGGAAAGAAAGACCAGAAGGAGTAATGAGACAAGTGATGGTGGGGAAGCTGAATGTTGAGGGAGGTGGAGGAAGGAGGAGATGAGCAG
TGTCAGTAAATACTGTGCATTCAGTAGAAGTTGAAGAATCATTGTTAGAAGCATTTCCAAACAAAACACTAAGCAAAATGGGAATTAGGC
TTATTTTGAATGCATCTTTAACTTACGAAAGATGTACTAATTGTGGGGGTGCCTGAGTCAGGCGGAGCTGACCCAGGGGTGGGAACGATG
GCAGCTGCCCAGGACCCATGTGCTTGGCCCAGGCTATGTCCTCGTGAGAGGTACTGGGGTCCACGGATATGTGTTGTGGGGCAGACAGTC
ACTGTGGGATGTCTTCAAAGTCAGCAGTTACAGAATTAGTTTACTTTGAATTTTGTTGTCTAAATAGCTCCTGCTTTATTTTTTAAATTA
AATTTTTTGTTTTTACTATCACAGGCTGGCCTAACTAATACAAAATAGGTGATGAACCTCTGGTTTTACCATAATGCAATGTGCCACGGA
AAGTTTGGGGGAGGTTTTTAATGTAATTGCACTCTGGTTAATTGGCTCGTACCAAGCCCTGCCTTATGACTTGTGGAAAGCTTCAAGGAG
TTCCACTGATGCAAAAGGGTCTTTTCCTAGCTTCCTGGTCTGATCAGTGCTATGAGATGGACAGATAAGTGTGAATGTTTTATACAGAAA
ATGGAAATGATACATTTCTCTTGTTAGGTGTTTTCATAAAATGTAGCATTTTTTTTCTTATGGAAATAAGAGTTTCAGGTGTCTCCCCAC
CTAGGGCAAATTCATGCACATTGTCATGTTATACCACCATTCTGGAAATGATTTCTGTGGATTTGAAATTGCACTTTTAATTTTATATAT
GACAGCATTTAAATGCAAACACTACCATGAATTTAATGTATAAAATGTTGTCAAACCAAGGGAAAAAACCACAGTTCACCATGTGGAGTT
TACTTTTTTTATATGAATGTTTGTTGTACTGTGTCTAAGCATAACTTCCCTAATGTCATTACTTTTACATACCAGATTTGACTGACCACT
AATGTAGTACTGGGGATAACTTAATATCCTATGTTGTGTCAAGACTCTTTGAAGACTTTCTTGAATTGCTTTCGTAAAGGTCTGAACACT
GTTAAGGAGAAAGCTGAGTATCAACTTGCCTTTCTGATAGAAATGTTTCTTGTGCCAGTTTTATTGTTGAGATATACTATTTTTTTCCTT
TTTTAATTCAGTTTTTTAAAAAAACAAATGTATTGTGGCTTCCAGTTACCAGGTTGTCTAGGTAATGACAGTAAACTGACTGTAGAATGA
TAATTGTGGTATAGTGACCAATAGATGCCAAACAGCTTGTGGCCTCACTAAAGGTGGGGTCGCTTAGTCCCCGGGAGTAAAATGAGTGAC
CTCAGAAACAAGAATTCCTGGAAAGGCACATGCCGAAGAGGAATATGGTATAATTTTAAATTTTAATGCAAAATTTTAATTTGTCTTTAT
TTTTTATCATTTGAACTGATAAGCACTTTTTGTGTCAATATAAAATATACTAAAACTGATGAAATGCTAAGACATGTCTTGTGAAGGAAG
GTTTCTTGGAGACCACTTTTATTTACTCATGAGAAGTGGAAGCTCCTAGTATCAGAAGAAGCTGATACATAGTGTCATGTGCTCAGTGGT
TGCCAAAGTCTACCAACTTTGGGGAGCTGCAGGGTTCTTTTTGGGAGGTGGGAGGAAGGGAGATGAGTTTTGTTATTTTGGGGTTTTCAA
GCATTGGAACCAAAGGCCAAATAATAAACAGCCTTTAGTTTTTAAAGTAAAATTCATTTTATTTGCAGAGTACACTTGTATGGTAGACTG
TTAAAGACAATTTTATGACTATTTATGCACATTATAATGGTTACATCTGCTTTTTGTCTTTAAAATAAAAAAAAAAATCAGAGAAAAGCC
CACCTTTGAATACGTGGCTGAAGATAACAGCCAAGAATTGGTCTTTCCTAAAAATGCAACAGATAATGCTGCTAGATTGTTATTTTGTTT
GCACTTTTTTTTGATTGGCATTTTAAAATCGGTATTTAAACTGAAGACATTGTCATGTTTTATTAATTTAACAAAGTTGAAAGTGACTGC
TCTGTACATCATGACCTTAACAATGTTAATGCTGTAAGTGAAAGTTCACTGTCGTCTGTATACTAAATTTATTGGTGTTTCTAACTTAAA
AGTAAGACTGCAGATTATCCCCCACCAGCCTTAGTCCAGGGGTGTGGCTCTGTCCGGGTGCAGTATGCAGTCATGTGGAACCTTGCTTTC

>54428_54428_4_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000437642_DYNC1LI2_chr16_66770147_ENST00000258198_length(amino acids)=892AA_BP=576
MQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETV
DDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADG
EYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTT
EDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG
LEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPR
DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR
YNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGVVKDFQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVV
CTKCDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTTPALVVEKDAVFIPAGWDNEKKI
AILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQVFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGT

--------------------------------------------------------------
>54428_54428_5_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000437642_DYNC1LI2_chr16_66770147_ENST00000379482_length(transcript)=2149nt_BP=2048nt
AATGCATGCCTGCCCTCCTGGGAATGAAGCACAGCAGGTCTCAGCCTCATCTTACCCAGCCCCCCACTCAAGATGGAGGTGCCTGGTTTG
AACACCTCTGACAAATGGAAGTCTGTGTTGTCCAGAGGCAATGCAGTGGGGGCTTAAGAAGATAACTCTGGACTTAGACCGCTTGGCTTC
AAATCAAAGAGTGCATGAACCAACCAGCTGGCCTAGTGATGATGTTAGGCAAGTGACTTCTCAGTTTCTTCATCTGCAAACTGGGAAATT
TCCTATCTCAGGGTTAAAAGAGAGGTAATCTTAGGTGCTTACCTAGCACATGCAATACCTGAACACCTTCTATGGCTGCCCCAAGGAGAG
CTGCAACCTGTTTGTGCTGAAGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGATCTTGACCAGAATACCAT
CGAGACCATGCGGAAGCCACGCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAAGTGGGACAAGAACCAGAT
CACATACAGGATCATTGGCTACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTTCCAAGTCTGGAGCGATGT
GACCCCACTGCGGTTTTCTCGAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCATGGCGATGGATACCCCTT
TGACGGTAAGGACGGACTCCTGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGATGACGATGAGCTATGGAC
CTTGGGAGAAGGCCAAGTGGTCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTTGTTCAATGGCAAGGAGTA
CAACAGCTGCACTGATACCGGCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGATGGCAAGTACGGCTTCTG
TCCCCATGAAGCCCTGTTCACCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCAGGGCACATCCTATGACAG
CTGCACCACTGAGGGCCGCACGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAAGTATGGCTTCTGCCCTGA
GACCGCCATGTCCACTGTTGGTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAACAAATATGAGAGCTGCAC
CAGCGCCGGCCGCAGTGACGGAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGGCTTCTGCCCTGACCAAGG
GTACAGCCTGTTCCTCGTGGCAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGGGGCCCTGATGGCACCCAT
TTACACCTACACCAAGAACTTCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTCTCCTGACATTGACCTTGG
CACCGGCCCCACCCCCACGCTGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCATCGCTCAGATCCGTGGTGA
GATCTTCTTCTTCAAGGACCGGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCTGGTGGCCACATTCTGGCC
TGAGCTCCCGGAAAAGATTGATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAATGAATACTGGATCTACTC
AGCCAGCACCCTGGAGCGAGGGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGTGGATGCCGCCTTTAACTG
GAGCAAAAACAAGAAGACATACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAATGGATCCTGGCTTCCCCAA
GCTCATCGCAGATGCCTGGAATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGTGAAAGATTTTCAAGACTA

>54428_54428_5_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000437642_DYNC1LI2_chr16_66770147_ENST00000379482_length(amino acids)=610AA_BP=576
MQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETV
DDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADG
EYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTT
EDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG
LEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPR
DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR

--------------------------------------------------------------
>54428_54428_6_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000437642_DYNC1LI2_chr16_66770147_ENST00000443351_length(transcript)=3242nt_BP=2048nt
AATGCATGCCTGCCCTCCTGGGAATGAAGCACAGCAGGTCTCAGCCTCATCTTACCCAGCCCCCCACTCAAGATGGAGGTGCCTGGTTTG
AACACCTCTGACAAATGGAAGTCTGTGTTGTCCAGAGGCAATGCAGTGGGGGCTTAAGAAGATAACTCTGGACTTAGACCGCTTGGCTTC
AAATCAAAGAGTGCATGAACCAACCAGCTGGCCTAGTGATGATGTTAGGCAAGTGACTTCTCAGTTTCTTCATCTGCAAACTGGGAAATT
TCCTATCTCAGGGTTAAAAGAGAGGTAATCTTAGGTGCTTACCTAGCACATGCAATACCTGAACACCTTCTATGGCTGCCCCAAGGAGAG
CTGCAACCTGTTTGTGCTGAAGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGATCTTGACCAGAATACCAT
CGAGACCATGCGGAAGCCACGCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAAGTGGGACAAGAACCAGAT
CACATACAGGATCATTGGCTACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTTCCAAGTCTGGAGCGATGT
GACCCCACTGCGGTTTTCTCGAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCATGGCGATGGATACCCCTT
TGACGGTAAGGACGGACTCCTGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGATGACGATGAGCTATGGAC
CTTGGGAGAAGGCCAAGTGGTCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTTGTTCAATGGCAAGGAGTA
CAACAGCTGCACTGATACCGGCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGATGGCAAGTACGGCTTCTG
TCCCCATGAAGCCCTGTTCACCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCAGGGCACATCCTATGACAG
CTGCACCACTGAGGGCCGCACGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAAGTATGGCTTCTGCCCTGA
GACCGCCATGTCCACTGTTGGTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAACAAATATGAGAGCTGCAC
CAGCGCCGGCCGCAGTGACGGAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGGCTTCTGCCCTGACCAAGG
GTACAGCCTGTTCCTCGTGGCAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGGGGCCCTGATGGCACCCAT
TTACACCTACACCAAGAACTTCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTCTCCTGACATTGACCTTGG
CACCGGCCCCACCCCCACGCTGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCATCGCTCAGATCCGTGGTGA
GATCTTCTTCTTCAAGGACCGGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCTGGTGGCCACATTCTGGCC
TGAGCTCCCGGAAAAGATTGATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAATGAATACTGGATCTACTC
AGCCAGCACCCTGGAGCGAGGGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGTGGATGCCGCCTTTAACTG
GAGCAAAAACAAGAAGACATACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAATGGATCCTGGCTTCCCCAA
GCTCATCGCAGATGCCTGGAATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGTGAAAGATTTTCAAGACTA
TATGGAACCTGAAGAAGGTTGTCAAGGTTCCCCACAGAGAAGAGGCCCTCTGACCTCAGGCTCCGATGAAGAAAATGTTGCCCTGCCTCT
GGGTGACAATGTGCTGACTCATAACCTGGGGATCCCGGTGTTGGTGGTGTGCACAAAGTGTGATGCGGTGAGTGTCCTGGAGAAGGAGCA
CGATTACAGGGATGAGCATTTGGACTTTATCCAGTCACACCTGCGGAGGTTCTGCCTTCAGTATGGAGCTGCCTTGATTTACACATCAGT
GAAAGAAGAGAAAAACCTCGACTTGTTGTATAAGTATATTGTTCATAAAACATACGGTTTCCACTTCACCACACCTGCCTTAGTTGTGGA
AAAGGATGCCGTTTTTATACCTGCAGGCTGGGACAATGAAAAGAAAATAGCTATTTTACATGAAAATTTTACAACCGTGAAGCCGGAAGA
TGCATATGAAGACTTTATTGTGAAACCTCCCGTGAGAAAGCTGGTCCACGACAAAGAGTTGGCAGCAGAAGATGAGCAGGTGTTCCTAAT
GAAGCAACAGTCACTCCTTGCCAAGCAACCAGCCACTCCCACGAGAGCTTCTGAATCTCCTGCAAGAGGACCCTCTGGCTCTCCAAGGAC
CCAGGGTCGGGGAGGGCCAGCCAGTGTGCCTAGCTCCTCCCCAGGCACGTCAGTAAAAAAGCCGGACCCAAACATCAAAAATAATGCAGC
AAGTGAAGGGGTGTTGGCCAGCTTCTTCAACAGTCTGTTGAGTAAAAAGACAGGCTCTCCTGGAAGTCCTGGTGCTGGTGGGGTGCAGAG
CACAGCCAAGAAGTCAGGACAAAAGACTGTGTTGTCAAATGTTCAGGAAGAACTGGATAGAATGACTCGAAAGCCAGACTCTATGGTAAC
AAACTCTTCAACAGAAAATGAAGCCTGAACCTCCTTAAAAAGTGCATATGTCGAATGACCAAATAACTATGTATATTGATCTGCTAAGAC
CAGGATTTTTCTGATATGGCACATGCTATCAGTTTTTTGGGGCAGGGGAGATGAACTTTAAAAAAAAAAAAAAAACTTCATTGGCTTGTC
CGAGTGTGAAATGCACATTTAGGAAGGTTACATGTCAGACCCTTTGTTAAGGATAACCCTTGGACTCTGGGGCATGTGGCTCTTTTGTGG

>54428_54428_6_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000437642_DYNC1LI2_chr16_66770147_ENST00000443351_length(amino acids)=892AA_BP=576
MQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETV
DDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADG
EYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTT
EDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMG
LEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPR
DKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWR
YNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGVVKDFQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVV
CTKCDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTTPALVVEKDAVFIPAGWDNEKKI
AILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQVFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGT

--------------------------------------------------------------
>54428_54428_7_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000543485_DYNC1LI2_chr16_66770147_ENST00000258198_length(transcript)=5570nt_BP=1791nt
AGATGTTGTCTTGTGAGCGTGCGCGCGCCTGGCTGGAGGGGCACTGAGCCTGGCCGCAGTGTTGCCAATACCTGAACACCTTCTATGGCT
GCCCCAAGGAGAGCTGCAACCTGTTTGTGCTGAAGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGATCTTG
ACCAGAATACCATCGAGACCATGCGGAAGCCACGCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAAGTGGG
ACAAGAACCAGATCACATACAGGATCATTGGCTACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTTCCAAG
TCTGGAGCGATGTGACCCCACTGCGGTTTTCTCGAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCATGGCG
ATGGATACCCCTTTGACGGTAAGGACGGACTCCTGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGATGACG
ATGAGCTATGGACCTTGGGAGAAGGCCAAGTGGTCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTTGTTCA
ATGGCAAGGAGTACAACAGCTGCACTGATACCGGCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGATGGCA
AGTACGGCTTCTGTCCCCATGAAGCCCTGTTCACCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCAGGGCA
CATCCTATGACAGCTGCACCACTGAGGGCCGCACGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAAGTATG
GCTTCTGCCCTGAGACCGCCATGTCCACTGTTGGTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAACAAAT
ATGAGAGCTGCACCAGCGCCGGCCGCAGTGACGGAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGGCTTCT
GCCCTGACCAAGGGTACAGCCTGTTCCTCGTGGCAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGGGGCCC
TGATGGCACCCATTTACACCTACACCAAGAACTTCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTCTCCTG
ACATTGACCTTGGCACCGGCCCCACCCCCACGCTGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCATCGCTC
AGATCCGTGGTGAGATCTTCTTCTTCAAGGACCGGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCTGGTGG
CCACATTCTGGCCTGAGCTCCCGGAAAAGATTGATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAATGAAT
ACTGGATCTACTCAGCCAGCACCCTGGAGCGAGGGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGTGGATG
CCGCCTTTAACTGGAGCAAAAACAAGAAGACATACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAATGGATC
CTGGCTTCCCCAAGCTCATCGCAGATGCCTGGAATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGTGAAAG
ATTTTCAAGACTATATGGAACCTGAAGAAGGTTGTCAAGGTTCCCCACAGAGAAGAGGCCCTCTGACCTCAGGCTCCGATGAAGAAAATG
TTGCCCTGCCTCTGGGTGACAATGTGCTGACTCATAACCTGGGGATCCCGGTGTTGGTGGTGTGCACAAAGTGTGATGCGGTGAGTGTCC
TGGAGAAGGAGCACGATTACAGGGATGAGCATTTGGACTTTATCCAGTCACACCTGCGGAGGTTCTGCCTTCAGTATGGAGCTGCCTTGA
TTTACACATCAGTGAAAGAAGAGAAAAACCTCGACTTGTTGTATAAGTATATTGTTCATAAAACATACGGTTTCCACTTCACCACACCTG
CCTTAGTTGTGGAAAAGGATGCCGTTTTTATACCTGCAGGCTGGGACAATGAAAAGAAAATAGCTATTTTACATGAAAATTTTACAACCG
TGAAGCCGGAAGATGCATATGAAGACTTTATTGTGAAACCTCCCGTGAGAAAGCTGGTCCACGACAAAGAGTTGGCAGCAGAAGATGAGC
AGGTGTTCCTAATGAAGCAACAGTCACTCCTTGCCAAGCAACCAGCCACTCCCACGAGAGCTTCTGAATCTCCTGCAAGAGGACCCTCTG
GCTCTCCAAGGACCCAGGGTCGGGGAGGGCCAGCCAGTGTGCCTAGCTCCTCCCCAGGCACGTCAGTAAAAAAGCCGGACCCAAACATCA
AAAATAATGCAGCAAGTGAAGGGGTGTTGGCCAGCTTCTTCAACAGTCTGTTGAGTAAAAAGACAGGCTCTCCTGGAAGTCCTGGTGCTG
GTGGGGTGCAGAGCACAGCCAAGAAGTCAGGACAAAAGACTGTGTTGTCAAATGTTCAGGAAGAACTGGATAGAATGACTCGAAAGCCAG
ACTCTATGGTAACAAACTCTTCAACAGAAAATGAAGCCTGAACCTCCTTAAAAAGTGCATATGTCGAATGACCAAATAACTATGTATATT
GATCTGCTAAGACCAGGATTTTTCTGATATGGCACATGCTATCAGTTTTTTGGGGCAGGGGAGATGAACTTTAAAAAAAAAAAAAAAACT
TCATTGGCTTGTCCGAGTGTGAAATGCACATTTAGGAAGGTTACATGTCAGACCCTTTGTTAAGGATAACCCTTGGACTCTGGGGCATGT
GGCTCTTTTGTGGGAGGCAAGCACATCTGGGCTTCTTGTGGAGGGGAAGGTAGAGTGAAAGAAAGAGGGCCCACTTTCTAACAGGGTGGA
GCAAATGAGACCAAGAAATCATTGGTAAGATGATGGTTAGTCTGACCAGTTTCATGTTAGTAAATTCACTTGTTCTTGGGAAGCAGATTA
AGTAGCAGAAAGTCCAGGAAAGAAAGACCAGAAGGAGTAATGAGACAAGTGATGGTGGGGAAGCTGAATGTTGAGGGAGGTGGAGGAAGG
AGGAGATGAGCAGTGTCAGTAAATACTGTGCATTCAGTAGAAGTTGAAGAATCATTGTTAGAAGCATTTCCAAACAAAACACTAAGCAAA
ATGGGAATTAGGCTTATTTTGAATGCATCTTTAACTTACGAAAGATGTACTAATTGTGGGGGTGCCTGAGTCAGGCGGAGCTGACCCAGG
GGTGGGAACGATGGCAGCTGCCCAGGACCCATGTGCTTGGCCCAGGCTATGTCCTCGTGAGAGGTACTGGGGTCCACGGATATGTGTTGT
GGGGCAGACAGTCACTGTGGGATGTCTTCAAAGTCAGCAGTTACAGAATTAGTTTACTTTGAATTTTGTTGTCTAAATAGCTCCTGCTTT
ATTTTTTAAATTAAATTTTTTGTTTTTACTATCACAGGCTGGCCTAACTAATACAAAATAGGTGATGAACCTCTGGTTTTACCATAATGC
AATGTGCCACGGAAAGTTTGGGGGAGGTTTTTAATGTAATTGCACTCTGGTTAATTGGCTCGTACCAAGCCCTGCCTTATGACTTGTGGA
AAGCTTCAAGGAGTTCCACTGATGCAAAAGGGTCTTTTCCTAGCTTCCTGGTCTGATCAGTGCTATGAGATGGACAGATAAGTGTGAATG
TTTTATACAGAAAATGGAAATGATACATTTCTCTTGTTAGGTGTTTTCATAAAATGTAGCATTTTTTTTCTTATGGAAATAAGAGTTTCA
GGTGTCTCCCCACCTAGGGCAAATTCATGCACATTGTCATGTTATACCACCATTCTGGAAATGATTTCTGTGGATTTGAAATTGCACTTT
TAATTTTATATATGACAGCATTTAAATGCAAACACTACCATGAATTTAATGTATAAAATGTTGTCAAACCAAGGGAAAAAACCACAGTTC
ACCATGTGGAGTTTACTTTTTTTATATGAATGTTTGTTGTACTGTGTCTAAGCATAACTTCCCTAATGTCATTACTTTTACATACCAGAT
TTGACTGACCACTAATGTAGTACTGGGGATAACTTAATATCCTATGTTGTGTCAAGACTCTTTGAAGACTTTCTTGAATTGCTTTCGTAA
AGGTCTGAACACTGTTAAGGAGAAAGCTGAGTATCAACTTGCCTTTCTGATAGAAATGTTTCTTGTGCCAGTTTTATTGTTGAGATATAC
TATTTTTTTCCTTTTTTAATTCAGTTTTTTAAAAAAACAAATGTATTGTGGCTTCCAGTTACCAGGTTGTCTAGGTAATGACAGTAAACT
GACTGTAGAATGATAATTGTGGTATAGTGACCAATAGATGCCAAACAGCTTGTGGCCTCACTAAAGGTGGGGTCGCTTAGTCCCCGGGAG
TAAAATGAGTGACCTCAGAAACAAGAATTCCTGGAAAGGCACATGCCGAAGAGGAATATGGTATAATTTTAAATTTTAATGCAAAATTTT
AATTTGTCTTTATTTTTTATCATTTGAACTGATAAGCACTTTTTGTGTCAATATAAAATATACTAAAACTGATGAAATGCTAAGACATGT
CTTGTGAAGGAAGGTTTCTTGGAGACCACTTTTATTTACTCATGAGAAGTGGAAGCTCCTAGTATCAGAAGAAGCTGATACATAGTGTCA
TGTGCTCAGTGGTTGCCAAAGTCTACCAACTTTGGGGAGCTGCAGGGTTCTTTTTGGGAGGTGGGAGGAAGGGAGATGAGTTTTGTTATT
TTGGGGTTTTCAAGCATTGGAACCAAAGGCCAAATAATAAACAGCCTTTAGTTTTTAAAGTAAAATTCATTTTATTTGCAGAGTACACTT
GTATGGTAGACTGTTAAAGACAATTTTATGACTATTTATGCACATTATAATGGTTACATCTGCTTTTTGTCTTTAAAATAAAAAAAAAAA
TCAGAGAAAAGCCCACCTTTGAATACGTGGCTGAAGATAACAGCCAAGAATTGGTCTTTCCTAAAAATGCAACAGATAATGCTGCTAGAT
TGTTATTTTGTTTGCACTTTTTTTTGATTGGCATTTTAAAATCGGTATTTAAACTGAAGACATTGTCATGTTTTATTAATTTAACAAAGT
TGAAAGTGACTGCTCTGTACATCATGACCTTAACAATGTTAATGCTGTAAGTGAAAGTTCACTGTCGTCTGTATACTAAATTTATTGGTG
TTTCTAACTTAAAAGTAAGACTGCAGATTATCCCCCACCAGCCTTAGTCCAGGGGTGTGGCTCTGTCCGGGTGCAGTATGCAGTCATGTG

>54428_54428_7_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000543485_DYNC1LI2_chr16_66770147_ENST00000258198_length(amino acids)=889AA_BP=573
MNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDA
FARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYC
KFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDY
DRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEH
SQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKP
MGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNE
VKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGVVKDFQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVVCTK
CDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTTPALVVEKDAVFIPAGWDNEKKIAIL
HENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQVFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGTSVK

--------------------------------------------------------------
>54428_54428_8_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000543485_DYNC1LI2_chr16_66770147_ENST00000379482_length(transcript)=1892nt_BP=1791nt
AGATGTTGTCTTGTGAGCGTGCGCGCGCCTGGCTGGAGGGGCACTGAGCCTGGCCGCAGTGTTGCCAATACCTGAACACCTTCTATGGCT
GCCCCAAGGAGAGCTGCAACCTGTTTGTGCTGAAGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGATCTTG
ACCAGAATACCATCGAGACCATGCGGAAGCCACGCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAAGTGGG
ACAAGAACCAGATCACATACAGGATCATTGGCTACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTTCCAAG
TCTGGAGCGATGTGACCCCACTGCGGTTTTCTCGAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCATGGCG
ATGGATACCCCTTTGACGGTAAGGACGGACTCCTGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGATGACG
ATGAGCTATGGACCTTGGGAGAAGGCCAAGTGGTCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTTGTTCA
ATGGCAAGGAGTACAACAGCTGCACTGATACCGGCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGATGGCA
AGTACGGCTTCTGTCCCCATGAAGCCCTGTTCACCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCAGGGCA
CATCCTATGACAGCTGCACCACTGAGGGCCGCACGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAAGTATG
GCTTCTGCCCTGAGACCGCCATGTCCACTGTTGGTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAACAAAT
ATGAGAGCTGCACCAGCGCCGGCCGCAGTGACGGAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGGCTTCT
GCCCTGACCAAGGGTACAGCCTGTTCCTCGTGGCAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGGGGCCC
TGATGGCACCCATTTACACCTACACCAAGAACTTCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTCTCCTG
ACATTGACCTTGGCACCGGCCCCACCCCCACGCTGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCATCGCTC
AGATCCGTGGTGAGATCTTCTTCTTCAAGGACCGGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCTGGTGG
CCACATTCTGGCCTGAGCTCCCGGAAAAGATTGATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAATGAAT
ACTGGATCTACTCAGCCAGCACCCTGGAGCGAGGGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGTGGATG
CCGCCTTTAACTGGAGCAAAAACAAGAAGACATACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAATGGATC
CTGGCTTCCCCAAGCTCATCGCAGATGCCTGGAATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGTGAAAG
ATTTTCAAGACTATATGGAACCTGAAGAAGGTTGTCAAGAGGGCCCACTTTCTAACAGGGTGGAGCAAATGAGACCAAGAAATCATTGGT

>54428_54428_8_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000543485_DYNC1LI2_chr16_66770147_ENST00000379482_length(amino acids)=607AA_BP=573
MNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDA
FARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYC
KFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDY
DRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEH
SQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKP
MGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNE

--------------------------------------------------------------
>54428_54428_9_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000543485_DYNC1LI2_chr16_66770147_ENST00000443351_length(transcript)=2985nt_BP=1791nt
AGATGTTGTCTTGTGAGCGTGCGCGCGCCTGGCTGGAGGGGCACTGAGCCTGGCCGCAGTGTTGCCAATACCTGAACACCTTCTATGGCT
GCCCCAAGGAGAGCTGCAACCTGTTTGTGCTGAAGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGATCTTG
ACCAGAATACCATCGAGACCATGCGGAAGCCACGCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAAGTGGG
ACAAGAACCAGATCACATACAGGATCATTGGCTACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTTCCAAG
TCTGGAGCGATGTGACCCCACTGCGGTTTTCTCGAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCATGGCG
ATGGATACCCCTTTGACGGTAAGGACGGACTCCTGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGATGACG
ATGAGCTATGGACCTTGGGAGAAGGCCAAGTGGTCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTTGTTCA
ATGGCAAGGAGTACAACAGCTGCACTGATACCGGCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGATGGCA
AGTACGGCTTCTGTCCCCATGAAGCCCTGTTCACCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCAGGGCA
CATCCTATGACAGCTGCACCACTGAGGGCCGCACGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAAGTATG
GCTTCTGCCCTGAGACCGCCATGTCCACTGTTGGTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAACAAAT
ATGAGAGCTGCACCAGCGCCGGCCGCAGTGACGGAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGGCTTCT
GCCCTGACCAAGGGTACAGCCTGTTCCTCGTGGCAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGGGGCCC
TGATGGCACCCATTTACACCTACACCAAGAACTTCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTCTCCTG
ACATTGACCTTGGCACCGGCCCCACCCCCACGCTGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCATCGCTC
AGATCCGTGGTGAGATCTTCTTCTTCAAGGACCGGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCTGGTGG
CCACATTCTGGCCTGAGCTCCCGGAAAAGATTGATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAATGAAT
ACTGGATCTACTCAGCCAGCACCCTGGAGCGAGGGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGTGGATG
CCGCCTTTAACTGGAGCAAAAACAAGAAGACATACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAATGGATC
CTGGCTTCCCCAAGCTCATCGCAGATGCCTGGAATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGTGAAAG
ATTTTCAAGACTATATGGAACCTGAAGAAGGTTGTCAAGGTTCCCCACAGAGAAGAGGCCCTCTGACCTCAGGCTCCGATGAAGAAAATG
TTGCCCTGCCTCTGGGTGACAATGTGCTGACTCATAACCTGGGGATCCCGGTGTTGGTGGTGTGCACAAAGTGTGATGCGGTGAGTGTCC
TGGAGAAGGAGCACGATTACAGGGATGAGCATTTGGACTTTATCCAGTCACACCTGCGGAGGTTCTGCCTTCAGTATGGAGCTGCCTTGA
TTTACACATCAGTGAAAGAAGAGAAAAACCTCGACTTGTTGTATAAGTATATTGTTCATAAAACATACGGTTTCCACTTCACCACACCTG
CCTTAGTTGTGGAAAAGGATGCCGTTTTTATACCTGCAGGCTGGGACAATGAAAAGAAAATAGCTATTTTACATGAAAATTTTACAACCG
TGAAGCCGGAAGATGCATATGAAGACTTTATTGTGAAACCTCCCGTGAGAAAGCTGGTCCACGACAAAGAGTTGGCAGCAGAAGATGAGC
AGGTGTTCCTAATGAAGCAACAGTCACTCCTTGCCAAGCAACCAGCCACTCCCACGAGAGCTTCTGAATCTCCTGCAAGAGGACCCTCTG
GCTCTCCAAGGACCCAGGGTCGGGGAGGGCCAGCCAGTGTGCCTAGCTCCTCCCCAGGCACGTCAGTAAAAAAGCCGGACCCAAACATCA
AAAATAATGCAGCAAGTGAAGGGGTGTTGGCCAGCTTCTTCAACAGTCTGTTGAGTAAAAAGACAGGCTCTCCTGGAAGTCCTGGTGCTG
GTGGGGTGCAGAGCACAGCCAAGAAGTCAGGACAAAAGACTGTGTTGTCAAATGTTCAGGAAGAACTGGATAGAATGACTCGAAAGCCAG
ACTCTATGGTAACAAACTCTTCAACAGAAAATGAAGCCTGAACCTCCTTAAAAAGTGCATATGTCGAATGACCAAATAACTATGTATATT
GATCTGCTAAGACCAGGATTTTTCTGATATGGCACATGCTATCAGTTTTTTGGGGCAGGGGAGATGAACTTTAAAAAAAAAAAAAAAACT
TCATTGGCTTGTCCGAGTGTGAAATGCACATTTAGGAAGGTTACATGTCAGACCCTTTGTTAAGGATAACCCTTGGACTCTGGGGCATGT

>54428_54428_9_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000543485_DYNC1LI2_chr16_66770147_ENST00000443351_length(amino acids)=889AA_BP=573
MNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDA
FARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYC
KFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDY
DRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEH
SQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKP
MGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNE
VKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGVVKDFQDYMEPEEGCQGSPQRRGPLTSGSDEENVALPLGDNVLTHNLGIPVLVVCTK
CDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHFTTPALVVEKDAVFIPAGWDNEKKIAIL
HENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQVFLMKQQSLLAKQPATPTRASESPARGPSGSPRTQGRGGPASVPSSSPGTSVK

--------------------------------------------------------------
>54428_54428_10_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000570308_DYNC1LI2_chr16_66770147_ENST00000258198_length(transcript)=6115nt_BP=2336nt
ACATCCGAGATGAACCCAGCCCTTGGTGTTCAAAATCACTTTAAGGGGAAGTAGAGCTTTTTCTTTCATGTACCTGGACCAGTAGTTCAC
TTACTCTGAAAGTCAAGAGGCCCCATGGACTGCCCAGCCCAGCTGCTGTGGAATGTGGCAGAGAAAGAGGGTGAGAGGGCCTGGATGACT
CCCATGCTGGGAGTATTATGCAAACGTGGGAGAAAAAAACATGCTTCCTCTCCTGGCCTACAGGAGCGCTTGAAAGCCTGCTCATCTGCA
AGCCCTAGGGCTGGACTCTACATCACAGCAGTGGATACTCCATCTCCATTGAGAACCCGATGACTGGTCACTGCCCAGCCCCACCCTCGA
CCCAACCAGGATGAAGAATGGGCAAGCCAGATAGCTACAGTAATCGACAGACAGACAAACAAGAGCATCGTATGACCCAGGGGCCAACAA
GTCCCACCCCAGTGACACCATCTCACTTTTGCAGAGCTCTTGCTCGCAAAGTGCAGCTAGGAGAACCCAGGCCTCCTGATGACAAATGCT
CCTTCTTTCTGCCCCCCACGTGCCAAGAGCGAGGAGGGAAGATAGCTGCTGGCTCACTGTGTGGTCGTGGCAATACCTGAACACCTTCTA
TGGCTGCCCCAAGGAGAGCTGCAACCTGTTTGTGCTGAAGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGA
TCTTGACCAGAATACCATCGAGACCATGCGGAAGCCACGCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAA
GTGGGACAAGAACCAGATCACATACAGGATCATTGGCTACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTT
CCAAGTCTGGAGCGATGTGACCCCACTGCGGTTTTCTCGAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCA
TGGCGATGGATACCCCTTTGACGGTAAGGACGGACTCCTGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGA
TGACGATGAGCTATGGACCTTGGGAGAAGGCCAAGTGGTCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTT
GTTCAATGGCAAGGAGTACAACAGCTGCACTGATACCGGCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGA
TGGCAAGTACGGCTTCTGTCCCCATGAAGCCCTGTTCACCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCA
GGGCACATCCTATGACAGCTGCACCACTGAGGGCCGCACGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAA
GTATGGCTTCTGCCCTGAGACCGCCATGTCCACTGTTGGTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAA
CAAATATGAGAGCTGCACCAGCGCCGGCCGCAGTGACGGAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGG
CTTCTGCCCTGACCAAGGGTACAGCCTGTTCCTCGTGGCAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGG
GGCCCTGATGGCACCCATTTACACCTACACCAAGAACTTCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTC
TCCTGACATTGACCTTGGCACCGGCCCCACCCCCACGCTGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCAT
CGCTCAGATCCGTGGTGAGATCTTCTTCTTCAAGGACCGGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCT
GGTGGCCACATTCTGGCCTGAGCTCCCGGAAAAGATTGATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAA
TGAATACTGGATCTACTCAGCCAGCACCCTGGAGCGAGGGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGT
GGATGCCGCCTTTAACTGGAGCAAAAACAAGAAGACATACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAAT
GGATCCTGGCTTCCCCAAGCTCATCGCAGATGCCTGGAATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGT
GAAAGATTTTCAAGACTATATGGAACCTGAAGAAGGTTGTCAAGGTTCCCCACAGAGAAGAGGCCCTCTGACCTCAGGCTCCGATGAAGA
AAATGTTGCCCTGCCTCTGGGTGACAATGTGCTGACTCATAACCTGGGGATCCCGGTGTTGGTGGTGTGCACAAAGTGTGATGCGGTGAG
TGTCCTGGAGAAGGAGCACGATTACAGGGATGAGCATTTGGACTTTATCCAGTCACACCTGCGGAGGTTCTGCCTTCAGTATGGAGCTGC
CTTGATTTACACATCAGTGAAAGAAGAGAAAAACCTCGACTTGTTGTATAAGTATATTGTTCATAAAACATACGGTTTCCACTTCACCAC
ACCTGCCTTAGTTGTGGAAAAGGATGCCGTTTTTATACCTGCAGGCTGGGACAATGAAAAGAAAATAGCTATTTTACATGAAAATTTTAC
AACCGTGAAGCCGGAAGATGCATATGAAGACTTTATTGTGAAACCTCCCGTGAGAAAGCTGGTCCACGACAAAGAGTTGGCAGCAGAAGA
TGAGCAGGTGTTCCTAATGAAGCAACAGTCACTCCTTGCCAAGCAACCAGCCACTCCCACGAGAGCTTCTGAATCTCCTGCAAGAGGACC
CTCTGGCTCTCCAAGGACCCAGGGTCGGGGAGGGCCAGCCAGTGTGCCTAGCTCCTCCCCAGGCACGTCAGTAAAAAAGCCGGACCCAAA
CATCAAAAATAATGCAGCAAGTGAAGGGGTGTTGGCCAGCTTCTTCAACAGTCTGTTGAGTAAAAAGACAGGCTCTCCTGGAAGTCCTGG
TGCTGGTGGGGTGCAGAGCACAGCCAAGAAGTCAGGACAAAAGACTGTGTTGTCAAATGTTCAGGAAGAACTGGATAGAATGACTCGAAA
GCCAGACTCTATGGTAACAAACTCTTCAACAGAAAATGAAGCCTGAACCTCCTTAAAAAGTGCATATGTCGAATGACCAAATAACTATGT
ATATTGATCTGCTAAGACCAGGATTTTTCTGATATGGCACATGCTATCAGTTTTTTGGGGCAGGGGAGATGAACTTTAAAAAAAAAAAAA
AAACTTCATTGGCTTGTCCGAGTGTGAAATGCACATTTAGGAAGGTTACATGTCAGACCCTTTGTTAAGGATAACCCTTGGACTCTGGGG
CATGTGGCTCTTTTGTGGGAGGCAAGCACATCTGGGCTTCTTGTGGAGGGGAAGGTAGAGTGAAAGAAAGAGGGCCCACTTTCTAACAGG
GTGGAGCAAATGAGACCAAGAAATCATTGGTAAGATGATGGTTAGTCTGACCAGTTTCATGTTAGTAAATTCACTTGTTCTTGGGAAGCA
GATTAAGTAGCAGAAAGTCCAGGAAAGAAAGACCAGAAGGAGTAATGAGACAAGTGATGGTGGGGAAGCTGAATGTTGAGGGAGGTGGAG
GAAGGAGGAGATGAGCAGTGTCAGTAAATACTGTGCATTCAGTAGAAGTTGAAGAATCATTGTTAGAAGCATTTCCAAACAAAACACTAA
GCAAAATGGGAATTAGGCTTATTTTGAATGCATCTTTAACTTACGAAAGATGTACTAATTGTGGGGGTGCCTGAGTCAGGCGGAGCTGAC
CCAGGGGTGGGAACGATGGCAGCTGCCCAGGACCCATGTGCTTGGCCCAGGCTATGTCCTCGTGAGAGGTACTGGGGTCCACGGATATGT
GTTGTGGGGCAGACAGTCACTGTGGGATGTCTTCAAAGTCAGCAGTTACAGAATTAGTTTACTTTGAATTTTGTTGTCTAAATAGCTCCT
GCTTTATTTTTTAAATTAAATTTTTTGTTTTTACTATCACAGGCTGGCCTAACTAATACAAAATAGGTGATGAACCTCTGGTTTTACCAT
AATGCAATGTGCCACGGAAAGTTTGGGGGAGGTTTTTAATGTAATTGCACTCTGGTTAATTGGCTCGTACCAAGCCCTGCCTTATGACTT
GTGGAAAGCTTCAAGGAGTTCCACTGATGCAAAAGGGTCTTTTCCTAGCTTCCTGGTCTGATCAGTGCTATGAGATGGACAGATAAGTGT
GAATGTTTTATACAGAAAATGGAAATGATACATTTCTCTTGTTAGGTGTTTTCATAAAATGTAGCATTTTTTTTCTTATGGAAATAAGAG
TTTCAGGTGTCTCCCCACCTAGGGCAAATTCATGCACATTGTCATGTTATACCACCATTCTGGAAATGATTTCTGTGGATTTGAAATTGC
ACTTTTAATTTTATATATGACAGCATTTAAATGCAAACACTACCATGAATTTAATGTATAAAATGTTGTCAAACCAAGGGAAAAAACCAC
AGTTCACCATGTGGAGTTTACTTTTTTTATATGAATGTTTGTTGTACTGTGTCTAAGCATAACTTCCCTAATGTCATTACTTTTACATAC
CAGATTTGACTGACCACTAATGTAGTACTGGGGATAACTTAATATCCTATGTTGTGTCAAGACTCTTTGAAGACTTTCTTGAATTGCTTT
CGTAAAGGTCTGAACACTGTTAAGGAGAAAGCTGAGTATCAACTTGCCTTTCTGATAGAAATGTTTCTTGTGCCAGTTTTATTGTTGAGA
TATACTATTTTTTTCCTTTTTTAATTCAGTTTTTTAAAAAAACAAATGTATTGTGGCTTCCAGTTACCAGGTTGTCTAGGTAATGACAGT
AAACTGACTGTAGAATGATAATTGTGGTATAGTGACCAATAGATGCCAAACAGCTTGTGGCCTCACTAAAGGTGGGGTCGCTTAGTCCCC
GGGAGTAAAATGAGTGACCTCAGAAACAAGAATTCCTGGAAAGGCACATGCCGAAGAGGAATATGGTATAATTTTAAATTTTAATGCAAA
ATTTTAATTTGTCTTTATTTTTTATCATTTGAACTGATAAGCACTTTTTGTGTCAATATAAAATATACTAAAACTGATGAAATGCTAAGA
CATGTCTTGTGAAGGAAGGTTTCTTGGAGACCACTTTTATTTACTCATGAGAAGTGGAAGCTCCTAGTATCAGAAGAAGCTGATACATAG
TGTCATGTGCTCAGTGGTTGCCAAAGTCTACCAACTTTGGGGAGCTGCAGGGTTCTTTTTGGGAGGTGGGAGGAAGGGAGATGAGTTTTG
TTATTTTGGGGTTTTCAAGCATTGGAACCAAAGGCCAAATAATAAACAGCCTTTAGTTTTTAAAGTAAAATTCATTTTATTTGCAGAGTA
CACTTGTATGGTAGACTGTTAAAGACAATTTTATGACTATTTATGCACATTATAATGGTTACATCTGCTTTTTGTCTTTAAAATAAAAAA
AAAAATCAGAGAAAAGCCCACCTTTGAATACGTGGCTGAAGATAACAGCCAAGAATTGGTCTTTCCTAAAAATGCAACAGATAATGCTGC
TAGATTGTTATTTTGTTTGCACTTTTTTTTGATTGGCATTTTAAAATCGGTATTTAAACTGAAGACATTGTCATGTTTTATTAATTTAAC
AAAGTTGAAAGTGACTGCTCTGTACATCATGACCTTAACAATGTTAATGCTGTAAGTGAAAGTTCACTGTCGTCTGTATACTAAATTTAT
TGGTGTTTCTAACTTAAAAGTAAGACTGCAGATTATCCCCCACCAGCCTTAGTCCAGGGGTGTGGCTCTGTCCGGGTGCAGTATGCAGTC

>54428_54428_10_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000570308_DYNC1LI2_chr16_66770147_ENST00000258198_length(amino acids)=916AA_BP=600
MLLLSAPHVPRARREDSCWLTVWSWQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRK
PKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSH
FDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFR
FQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRK
WGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFD
GIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQ
RVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGVVKDFQDYMEPEEGCQGSPQRRGPLTSGSD
EENVALPLGDNVLTHNLGIPVLVVCTKCDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHF
TTPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQVFLMKQQSLLAKQPATPTRASESPAR
GPSGSPRTQGRGGPASVPSSSPGTSVKKPDPNIKNNAASEGVLASFFNSLLSKKTGSPGSPGAGGVQSTAKKSGQKTVLSNVQEELDRMT

--------------------------------------------------------------
>54428_54428_11_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000570308_DYNC1LI2_chr16_66770147_ENST00000379482_length(transcript)=2437nt_BP=2336nt
ACATCCGAGATGAACCCAGCCCTTGGTGTTCAAAATCACTTTAAGGGGAAGTAGAGCTTTTTCTTTCATGTACCTGGACCAGTAGTTCAC
TTACTCTGAAAGTCAAGAGGCCCCATGGACTGCCCAGCCCAGCTGCTGTGGAATGTGGCAGAGAAAGAGGGTGAGAGGGCCTGGATGACT
CCCATGCTGGGAGTATTATGCAAACGTGGGAGAAAAAAACATGCTTCCTCTCCTGGCCTACAGGAGCGCTTGAAAGCCTGCTCATCTGCA
AGCCCTAGGGCTGGACTCTACATCACAGCAGTGGATACTCCATCTCCATTGAGAACCCGATGACTGGTCACTGCCCAGCCCCACCCTCGA
CCCAACCAGGATGAAGAATGGGCAAGCCAGATAGCTACAGTAATCGACAGACAGACAAACAAGAGCATCGTATGACCCAGGGGCCAACAA
GTCCCACCCCAGTGACACCATCTCACTTTTGCAGAGCTCTTGCTCGCAAAGTGCAGCTAGGAGAACCCAGGCCTCCTGATGACAAATGCT
CCTTCTTTCTGCCCCCCACGTGCCAAGAGCGAGGAGGGAAGATAGCTGCTGGCTCACTGTGTGGTCGTGGCAATACCTGAACACCTTCTA
TGGCTGCCCCAAGGAGAGCTGCAACCTGTTTGTGCTGAAGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGA
TCTTGACCAGAATACCATCGAGACCATGCGGAAGCCACGCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAA
GTGGGACAAGAACCAGATCACATACAGGATCATTGGCTACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTT
CCAAGTCTGGAGCGATGTGACCCCACTGCGGTTTTCTCGAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCA
TGGCGATGGATACCCCTTTGACGGTAAGGACGGACTCCTGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGA
TGACGATGAGCTATGGACCTTGGGAGAAGGCCAAGTGGTCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTT
GTTCAATGGCAAGGAGTACAACAGCTGCACTGATACCGGCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGA
TGGCAAGTACGGCTTCTGTCCCCATGAAGCCCTGTTCACCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCA
GGGCACATCCTATGACAGCTGCACCACTGAGGGCCGCACGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAA
GTATGGCTTCTGCCCTGAGACCGCCATGTCCACTGTTGGTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAA
CAAATATGAGAGCTGCACCAGCGCCGGCCGCAGTGACGGAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGG
CTTCTGCCCTGACCAAGGGTACAGCCTGTTCCTCGTGGCAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGG
GGCCCTGATGGCACCCATTTACACCTACACCAAGAACTTCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTC
TCCTGACATTGACCTTGGCACCGGCCCCACCCCCACGCTGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCAT
CGCTCAGATCCGTGGTGAGATCTTCTTCTTCAAGGACCGGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCT
GGTGGCCACATTCTGGCCTGAGCTCCCGGAAAAGATTGATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAA
TGAATACTGGATCTACTCAGCCAGCACCCTGGAGCGAGGGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGT
GGATGCCGCCTTTAACTGGAGCAAAAACAAGAAGACATACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAAT
GGATCCTGGCTTCCCCAAGCTCATCGCAGATGCCTGGAATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGT
GAAAGATTTTCAAGACTATATGGAACCTGAAGAAGGTTGTCAAGAGGGCCCACTTTCTAACAGGGTGGAGCAAATGAGACCAAGAAATCA

>54428_54428_11_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000570308_DYNC1LI2_chr16_66770147_ENST00000379482_length(amino acids)=634AA_BP=600
MLLLSAPHVPRARREDSCWLTVWSWQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRK
PKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSH
FDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFR
FQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRK
WGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFD
GIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQ
RVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGVVKDFQDYMEPEEGCQEGPLSNRVEQMRPR

--------------------------------------------------------------
>54428_54428_12_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000570308_DYNC1LI2_chr16_66770147_ENST00000443351_length(transcript)=3530nt_BP=2336nt
ACATCCGAGATGAACCCAGCCCTTGGTGTTCAAAATCACTTTAAGGGGAAGTAGAGCTTTTTCTTTCATGTACCTGGACCAGTAGTTCAC
TTACTCTGAAAGTCAAGAGGCCCCATGGACTGCCCAGCCCAGCTGCTGTGGAATGTGGCAGAGAAAGAGGGTGAGAGGGCCTGGATGACT
CCCATGCTGGGAGTATTATGCAAACGTGGGAGAAAAAAACATGCTTCCTCTCCTGGCCTACAGGAGCGCTTGAAAGCCTGCTCATCTGCA
AGCCCTAGGGCTGGACTCTACATCACAGCAGTGGATACTCCATCTCCATTGAGAACCCGATGACTGGTCACTGCCCAGCCCCACCCTCGA
CCCAACCAGGATGAAGAATGGGCAAGCCAGATAGCTACAGTAATCGACAGACAGACAAACAAGAGCATCGTATGACCCAGGGGCCAACAA
GTCCCACCCCAGTGACACCATCTCACTTTTGCAGAGCTCTTGCTCGCAAAGTGCAGCTAGGAGAACCCAGGCCTCCTGATGACAAATGCT
CCTTCTTTCTGCCCCCCACGTGCCAAGAGCGAGGAGGGAAGATAGCTGCTGGCTCACTGTGTGGTCGTGGCAATACCTGAACACCTTCTA
TGGCTGCCCCAAGGAGAGCTGCAACCTGTTTGTGCTGAAGGACACACTAAAGAAGATGCAGAAGTTCTTTGGACTGCCCCAGACAGGTGA
TCTTGACCAGAATACCATCGAGACCATGCGGAAGCCACGCTGCGGCAACCCAGATGTGGCCAACTACAACTTCTTCCCTCGCAAGCCCAA
GTGGGACAAGAACCAGATCACATACAGGATCATTGGCTACACACCTGATCTGGACCCAGAGACAGTGGATGATGCCTTTGCTCGTGCCTT
CCAAGTCTGGAGCGATGTGACCCCACTGCGGTTTTCTCGAATCCATGATGGAGAGGCAGACATCATGATCAACTTTGGCCGCTGGGAGCA
TGGCGATGGATACCCCTTTGACGGTAAGGACGGACTCCTGGCTCATGCCTTCGCCCCAGGCACTGGTGTTGGGGGAGACTCCCATTTTGA
TGACGATGAGCTATGGACCTTGGGAGAAGGCCAAGTGGTCCGTGTGAAGTATGGGAACGCCGATGGGGAGTACTGCAAGTTCCCCTTCTT
GTTCAATGGCAAGGAGTACAACAGCTGCACTGATACCGGCCGCAGCGATGGCTTCCTCTGGTGCTCCACCACCTACAACTTTGAGAAGGA
TGGCAAGTACGGCTTCTGTCCCCATGAAGCCCTGTTCACCATGGGCGGCAACGCTGAAGGACAGCCCTGCAAGTTTCCATTCCGCTTCCA
GGGCACATCCTATGACAGCTGCACCACTGAGGGCCGCACGGATGGCTACCGCTGGTGCGGCACCACTGAGGACTACGACCGCGACAAGAA
GTATGGCTTCTGCCCTGAGACCGCCATGTCCACTGTTGGTGGGAACTCAGAAGGTGCCCCCTGTGTCTTCCCCTTCACTTTCCTGGGCAA
CAAATATGAGAGCTGCACCAGCGCCGGCCGCAGTGACGGAAAGATGTGGTGTGCGACCACAGCCAACTACGATGATGACCGCAAGTGGGG
CTTCTGCCCTGACCAAGGGTACAGCCTGTTCCTCGTGGCAGCCCACGAGTTTGGCCACGCCATGGGGCTGGAGCACTCCCAAGACCCTGG
GGCCCTGATGGCACCCATTTACACCTACACCAAGAACTTCCGTCTGTCCCAGGATGACATCAAGGGCATTCAGGAGCTCTATGGGGCCTC
TCCTGACATTGACCTTGGCACCGGCCCCACCCCCACGCTGGGCCCTGTCACTCCTGAGATCTGCAAACAGGACATTGTATTTGATGGCAT
CGCTCAGATCCGTGGTGAGATCTTCTTCTTCAAGGACCGGTTCATTTGGCGGACTGTGACGCCACGTGACAAGCCCATGGGGCCCCTGCT
GGTGGCCACATTCTGGCCTGAGCTCCCGGAAAAGATTGATGCGGTATACGAGGCCCCACAGGAGGAGAAGGCTGTGTTCTTTGCAGGGAA
TGAATACTGGATCTACTCAGCCAGCACCCTGGAGCGAGGGTACCCCAAGCCACTGACCAGCCTGGGACTGCCCCCTGATGTCCAGCGAGT
GGATGCCGCCTTTAACTGGAGCAAAAACAAGAAGACATACATCTTTGCTGGAGACAAATTCTGGAGATACAATGAGGTGAAGAAGAAAAT
GGATCCTGGCTTCCCCAAGCTCATCGCAGATGCCTGGAATGCCATCCCCGATAACCTGGATGCCGTCGTGGACCTGCAGGGCGGCGTTGT
GAAAGATTTTCAAGACTATATGGAACCTGAAGAAGGTTGTCAAGGTTCCCCACAGAGAAGAGGCCCTCTGACCTCAGGCTCCGATGAAGA
AAATGTTGCCCTGCCTCTGGGTGACAATGTGCTGACTCATAACCTGGGGATCCCGGTGTTGGTGGTGTGCACAAAGTGTGATGCGGTGAG
TGTCCTGGAGAAGGAGCACGATTACAGGGATGAGCATTTGGACTTTATCCAGTCACACCTGCGGAGGTTCTGCCTTCAGTATGGAGCTGC
CTTGATTTACACATCAGTGAAAGAAGAGAAAAACCTCGACTTGTTGTATAAGTATATTGTTCATAAAACATACGGTTTCCACTTCACCAC
ACCTGCCTTAGTTGTGGAAAAGGATGCCGTTTTTATACCTGCAGGCTGGGACAATGAAAAGAAAATAGCTATTTTACATGAAAATTTTAC
AACCGTGAAGCCGGAAGATGCATATGAAGACTTTATTGTGAAACCTCCCGTGAGAAAGCTGGTCCACGACAAAGAGTTGGCAGCAGAAGA
TGAGCAGGTGTTCCTAATGAAGCAACAGTCACTCCTTGCCAAGCAACCAGCCACTCCCACGAGAGCTTCTGAATCTCCTGCAAGAGGACC
CTCTGGCTCTCCAAGGACCCAGGGTCGGGGAGGGCCAGCCAGTGTGCCTAGCTCCTCCCCAGGCACGTCAGTAAAAAAGCCGGACCCAAA
CATCAAAAATAATGCAGCAAGTGAAGGGGTGTTGGCCAGCTTCTTCAACAGTCTGTTGAGTAAAAAGACAGGCTCTCCTGGAAGTCCTGG
TGCTGGTGGGGTGCAGAGCACAGCCAAGAAGTCAGGACAAAAGACTGTGTTGTCAAATGTTCAGGAAGAACTGGATAGAATGACTCGAAA
GCCAGACTCTATGGTAACAAACTCTTCAACAGAAAATGAAGCCTGAACCTCCTTAAAAAGTGCATATGTCGAATGACCAAATAACTATGT
ATATTGATCTGCTAAGACCAGGATTTTTCTGATATGGCACATGCTATCAGTTTTTTGGGGCAGGGGAGATGAACTTTAAAAAAAAAAAAA
AAACTTCATTGGCTTGTCCGAGTGTGAAATGCACATTTAGGAAGGTTACATGTCAGACCCTTTGTTAAGGATAACCCTTGGACTCTGGGG

>54428_54428_12_MMP2-DYNC1LI2_MMP2_chr16_55536800_ENST00000570308_DYNC1LI2_chr16_66770147_ENST00000443351_length(amino acids)=916AA_BP=600
MLLLSAPHVPRARREDSCWLTVWSWQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRK
PKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSH
FDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFR
FQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRK
WGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFD
GIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQ
RVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGVVKDFQDYMEPEEGCQGSPQRRGPLTSGSD
EENVALPLGDNVLTHNLGIPVLVVCTKCDAVSVLEKEHDYRDEHLDFIQSHLRRFCLQYGAALIYTSVKEEKNLDLLYKYIVHKTYGFHF
TTPALVVEKDAVFIPAGWDNEKKIAILHENFTTVKPEDAYEDFIVKPPVRKLVHDKELAAEDEQVFLMKQQSLLAKQPATPTRASESPAR
GPSGSPRTQGRGGPASVPSSSPGTSVKKPDPNIKNNAASEGVLASFFNSLLSKKTGSPGSPGAGGVQSTAKKSGQKTVLSNVQEELDRMT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MMP2-DYNC1LI2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MMP2-DYNC1LI2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MMP2-DYNC1LI2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource