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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MOB1B-PPAPDC1A (FusionGDB2 ID:54491)

Fusion Gene Summary for MOB1B-PPAPDC1A

check button Fusion gene summary
Fusion gene informationFusion gene name: MOB1B-PPAPDC1A
Fusion gene ID: 54491
HgeneTgene
Gene symbol

MOB1B

PPAPDC1A

Gene ID

92597

196051

Gene nameMOB kinase activator 1Bphospholipid phosphatase 4
SynonymsMATS2|MOB4A|MOBKL1ADPPL2|PPAPDC1|PPAPDC1A
Cytomap

4q13.3

10q26.12

Type of geneprotein-codingprotein-coding
DescriptionMOB kinase activator 1BMOB1 Mps One Binder homolog BMOB1, Mps One Binder kinase activator-like 1Amob1 homolog 1Amob1Amps one binder kinase activator-like 1Aphospholipid phosphatase 4diacylglycerol pyrophosphate like 2diacylglycerol pyrophosphate phosphatase-like 2phosphatidate phosphatase PPAPDC1Aphosphatidic acid phosphatase type 2 domain containing 1Aphosphatidic acid phosphatase type 2 domain-contain
Modification date2020032020200313
UniProtAcc

Q7L9L4

.
Ensembl transtripts involved in fusion geneENST00000511449, ENST00000309395, 
ENST00000396051, 		ENST00000369073, 
ENST00000398248, ENST00000398250, 
ENST00000439221, ENST00000541332, 
ENST00000496437, 
Fusion gene scores* DoF score9 X 3 X 8=2168 X 6 X 6=288
# samples 1113
** MAII scorelog2(11/216*10)=-0.973527788638809
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/288*10)=-1.14755718841386
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MOB1B [Title/Abstract] AND PPAPDC1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMOB1B(71768267)-PPAPDC1A(122263329), # samples:1
MOB1B(71768267)-PPAPDC1A(122263330), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMOB1B

GO:0031952

regulation of protein autophosphorylation

15197186

HgeneMOB1B

GO:0035329

hippo signaling

19739119

TgenePPAPDC1A

GO:0046839

phospholipid dephosphorylation

17590538


check buttonFusion gene breakpoints across MOB1B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PPAPDC1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AQ-A04L-01BMOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
ChimerDB4BRCATCGA-AQ-A04LMOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+


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Fusion Gene ORF analysis for MOB1B-PPAPDC1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000511449ENST00000369073MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
3UTR-3CDSENST00000511449ENST00000369073MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
3UTR-3CDSENST00000511449ENST00000398248MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
3UTR-3CDSENST00000511449ENST00000398248MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
3UTR-3CDSENST00000511449ENST00000398250MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
3UTR-3CDSENST00000511449ENST00000398250MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
3UTR-3CDSENST00000511449ENST00000439221MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
3UTR-3CDSENST00000511449ENST00000439221MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
3UTR-3CDSENST00000511449ENST00000541332MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
3UTR-3CDSENST00000511449ENST00000541332MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
3UTR-intronENST00000511449ENST00000496437MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
3UTR-intronENST00000511449ENST00000496437MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
5CDS-intronENST00000309395ENST00000496437MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
5CDS-intronENST00000309395ENST00000496437MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
5UTR-3CDSENST00000396051ENST00000369073MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
5UTR-3CDSENST00000396051ENST00000369073MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
5UTR-3CDSENST00000396051ENST00000398248MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
5UTR-3CDSENST00000396051ENST00000398248MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
5UTR-3CDSENST00000396051ENST00000398250MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
5UTR-3CDSENST00000396051ENST00000398250MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
5UTR-3CDSENST00000396051ENST00000439221MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
5UTR-3CDSENST00000396051ENST00000439221MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
5UTR-3CDSENST00000396051ENST00000541332MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
5UTR-3CDSENST00000396051ENST00000541332MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
5UTR-intronENST00000396051ENST00000496437MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
5UTR-intronENST00000396051ENST00000496437MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
In-frameENST00000309395ENST00000369073MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
In-frameENST00000309395ENST00000369073MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
In-frameENST00000309395ENST00000398248MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
In-frameENST00000309395ENST00000398248MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
In-frameENST00000309395ENST00000398250MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
In-frameENST00000309395ENST00000398250MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
In-frameENST00000309395ENST00000439221MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
In-frameENST00000309395ENST00000439221MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+
In-frameENST00000309395ENST00000541332MOB1Bchr4

71768267

+PPAPDC1Achr10

122263330

+
In-frameENST00000309395ENST00000541332MOB1Bchr4

71768267

+PPAPDC1Achr10

122263329

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000309395MOB1Bchr471768267+ENST00000398250PPAPDC1Achr10122263329+1328215105974289
ENST00000309395MOB1Bchr471768267+ENST00000439221PPAPDC1Achr10122263329+1139215105785226
ENST00000309395MOB1Bchr471768267+ENST00000398248PPAPDC1Achr10122263329+877215105449114
ENST00000309395MOB1Bchr471768267+ENST00000541332PPAPDC1Achr10122263329+1524215105860251
ENST00000309395MOB1Bchr471768267+ENST00000369073PPAPDC1Achr10122263329+1324215105974289
ENST00000309395MOB1Bchr471768267+ENST00000398250PPAPDC1Achr10122263330+1328215105974289
ENST00000309395MOB1Bchr471768267+ENST00000439221PPAPDC1Achr10122263330+1139215105785226
ENST00000309395MOB1Bchr471768267+ENST00000398248PPAPDC1Achr10122263330+877215105449114
ENST00000309395MOB1Bchr471768267+ENST00000541332PPAPDC1Achr10122263330+1524215105860251
ENST00000309395MOB1Bchr471768267+ENST00000369073PPAPDC1Achr10122263330+1324215105974289

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000309395ENST00000398250MOB1Bchr471768267+PPAPDC1Achr10122263329+0.0209214760.97907853
ENST00000309395ENST00000439221MOB1Bchr471768267+PPAPDC1Achr10122263329+0.010447240.98955274
ENST00000309395ENST00000398248MOB1Bchr471768267+PPAPDC1Achr10122263329+0.424049260.57595074
ENST00000309395ENST00000541332MOB1Bchr471768267+PPAPDC1Achr10122263329+0.146257030.853743
ENST00000309395ENST00000369073MOB1Bchr471768267+PPAPDC1Achr10122263329+0.0218857270.97811425
ENST00000309395ENST00000398250MOB1Bchr471768267+PPAPDC1Achr10122263330+0.0209214760.97907853
ENST00000309395ENST00000439221MOB1Bchr471768267+PPAPDC1Achr10122263330+0.010447240.98955274
ENST00000309395ENST00000398248MOB1Bchr471768267+PPAPDC1Achr10122263330+0.424049260.57595074
ENST00000309395ENST00000541332MOB1Bchr471768267+PPAPDC1Achr10122263330+0.146257030.853743
ENST00000309395ENST00000369073MOB1Bchr471768267+PPAPDC1Achr10122263330+0.0218857270.97811425

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Fusion Genomic Features for MOB1B-PPAPDC1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MOB1B-PPAPDC1A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:71768267/chr10:122263329)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MOB1B

Q7L9L4

.
FUNCTION: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L. {ECO:0000269|PubMed:15067004, ECO:0000269|PubMed:19739119}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039824803102_1101897.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039824803143_1461897.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039824803195_2051897.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039825007102_11018272.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039825007143_14618272.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039825007195_20518272.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000043922105102_11018209.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000043922105143_14618209.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000043922105195_20518209.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039824803102_1101897.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039824803143_1461897.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039824803195_2051897.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039825007102_11018272.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039825007143_14618272.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039825007195_20518272.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000043922105102_11018209.0RegionPhosphatase sequence motif I
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000043922105143_14618209.0RegionPhosphatase sequence motif II
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000043922105195_20518209.0RegionPhosphatase sequence motif III
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039824803142_1621897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039824803179_1991897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039824803202_2221897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST000003982480349_691897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST000003982480384_1041897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039825007142_16218272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039825007179_19918272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000039825007202_22218272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST000003982500749_6918272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST000003982500784_10418272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000043922105142_16218209.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000043922105179_19918209.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST0000043922105202_22218209.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST000004392210549_6918209.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST000004392210584_10418209.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039824803142_1621897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039824803179_1991897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039824803202_2221897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST000003982480349_691897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST000003982480384_1041897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039825007142_16218272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039825007179_19918272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000039825007202_22218272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST000003982500749_6918272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST000003982500784_10418272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000043922105142_16218209.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000043922105179_19918209.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST0000043922105202_22218209.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST000004392210549_6918209.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST000004392210584_10418209.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePPAPDC1Achr4:71768267chr10:122263329ENST00000398248034_241897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST00000398250074_2418272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263329ENST00000439221054_2418209.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST00000398248034_241897.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST00000398250074_2418272.0TransmembraneHelical
TgenePPAPDC1Achr4:71768267chr10:122263330ENST00000439221054_2418209.0TransmembraneHelical


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Fusion Gene Sequence for MOB1B-PPAPDC1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>54491_54491_1_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263329_ENST00000369073_length(transcript)=1324nt_BP=215nt
GAGCGCTACCCACTTCCGCCCCCTCCCCCTGCCATTGGAACTAGCTGAGCCGAACTAGTTGCGGCCACCGAGCAGCCGGCTCTCGGCACC
TCCTCCTCCGCCTCCCTGTCTCCTGTTCCATTCGCCTTTCCTCTTCTTTCCTGGCCCACGCCGCTCCGAGGCCTCGCGACCGCCGAGCCT
GCAGCCTGCCCCGCGGCCAACATGAGCTTCTTGTTTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGG
CTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGTTATTTGT
GTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGCTCTTGCTTTGAATGGAGTCTGC
ACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGGAGTGATGAACTCGGAAATGCAT
TGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGCCTTTTCGGGCCTTGGCTTCACG
ACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTAC
TGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTT
GCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGCCTCACTG
AAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTCCTGGGAG
GATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCAGTTGTTT
CTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTTGCAAGTG
AAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAATGTTTGCT

>54491_54491_1_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263329_ENST00000369073_length(amino acids)=289AA_BP=37
MSPVPFAFPLLSWPTPLRGLATAEPAACPAANMSFLFFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKII
RRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLA
GKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEER

--------------------------------------------------------------
>54491_54491_2_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263329_ENST00000398248_length(transcript)=877nt_BP=215nt
GAGCGCTACCCACTTCCGCCCCCTCCCCCTGCCATTGGAACTAGCTGAGCCGAACTAGTTGCGGCCACCGAGCAGCCGGCTCTCGGCACC
TCCTCCTCCGCCTCCCTGTCTCCTGTTCCATTCGCCTTTCCTCTTCTTTCCTGGCCCACGCCGCTCCGAGGCCTCGCGACCGCCGAGCCT
GCAGCCTGCCCCGCGGCCAACATGAGCTTCTTGTTTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGG
CTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTATTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTTG
CATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGCCTCACTGA
AGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTCCTGGGAGG
ATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCAGTTGTTTC
TCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTTGCAAGTGA
AGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAATGTTTGCTG

>54491_54491_2_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263329_ENST00000398248_length(amino acids)=114AA_BP=37
MSPVPFAFPLLSWPTPLRGLATAEPAACPAANMSFLFFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFIPLWVESSASFLHTFAT

--------------------------------------------------------------
>54491_54491_3_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263329_ENST00000398250_length(transcript)=1328nt_BP=215nt
GAGCGCTACCCACTTCCGCCCCCTCCCCCTGCCATTGGAACTAGCTGAGCCGAACTAGTTGCGGCCACCGAGCAGCCGGCTCTCGGCACC
TCCTCCTCCGCCTCCCTGTCTCCTGTTCCATTCGCCTTTCCTCTTCTTTCCTGGCCCACGCCGCTCCGAGGCCTCGCGACCGCCGAGCCT
GCAGCCTGCCCCGCGGCCAACATGAGCTTCTTGTTTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGG
CTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGTTATTTGT
GTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGCTCTTGCTTTGAATGGAGTCTGC
ACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGGAGTGATGAACTCGGAAATGCAT
TGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGCCTTTTCGGGCCTTGGCTTCACG
ACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTAC
TGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTT
GCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGCCTCACTG
AAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTCCTGGGAG
GATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCAGTTGTTT
CTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTTGCAAGTG
AAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAATGTTTGCT

>54491_54491_3_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263329_ENST00000398250_length(amino acids)=289AA_BP=37
MSPVPFAFPLLSWPTPLRGLATAEPAACPAANMSFLFFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKII
RRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLA
GKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEER

--------------------------------------------------------------
>54491_54491_4_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263329_ENST00000439221_length(transcript)=1139nt_BP=215nt
GAGCGCTACCCACTTCCGCCCCCTCCCCCTGCCATTGGAACTAGCTGAGCCGAACTAGTTGCGGCCACCGAGCAGCCGGCTCTCGGCACC
TCCTCCTCCGCCTCCCTGTCTCCTGTTCCATTCGCCTTTCCTCTTCTTTCCTGGCCCACGCCGCTCCGAGGCCTCGCGACCGCCGAGCCT
GCAGCCTGCCCCGCGGCCAACATGAGCTTCTTGTTTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGG
CTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGTTATTTGT
GTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTAC
TTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTACTGCGCCATG
ATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATT
TGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAG
GAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTCCTGGGAGGATGGACAC
TAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTC
ATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTTGCAAGTGAAGGACAAC
AATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAATGTTTGCTGTAACAGCC

>54491_54491_4_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263329_ENST00000439221_length(amino acids)=226AA_BP=37
MSPVPFAFPLLSWPTPLRGLATAEPAACPAANMSFLFFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKII
RRTDKTEIKEAFLVAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQH

--------------------------------------------------------------
>54491_54491_5_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263329_ENST00000541332_length(transcript)=1524nt_BP=215nt
GAGCGCTACCCACTTCCGCCCCCTCCCCCTGCCATTGGAACTAGCTGAGCCGAACTAGTTGCGGCCACCGAGCAGCCGGCTCTCGGCACC
TCCTCCTCCGCCTCCCTGTCTCCTGTTCCATTCGCCTTTCCTCTTCTTTCCTGGCCCACGCCGCTCCGAGGCCTCGCGACCGCCGAGCCT
GCAGCCTGCCCCGCGGCCAACATGAGCTTCTTGTTTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGG
CTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGTTATTTGT
GTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGCTCTTGCTTTGAATGGAGTCTGC
ACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGGAGTGATGAACTCGGAAATGCAT
TGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGCCTTTTCGGGCCTTGGCTTCACG
ACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTAC
TGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGTTGGCTGCTGTGTATGGCAGGGCCCACAGTCACAT
TTACCATCGGCTGCCAACCCCCGCCTCTGTCTGGGAACCTCTGAACCTTGACTGCCCATCTAAGTCCACCCGCCTCTGTGTTGGTGCCTA
GGAGAGCGTAAGAAGCCTCAGCCCCTGGCTCACCCCTCCCTCCGGTCAAAGTCCACTGCATATCCTGCTTTCAGCCTCAAGAGAGGCATT
CTCAGTCAGGACTTCTGCCCTCTTCCTGCCTCCAGGATAGCCCTGGTGTTTCCCCGTGATGTAATTCCCAGGGAAGATGGACGTTGATTG
CTCCCAAGTCTCACTGGCATCCTTCCTTTGTTTTACTCAAGGGAACCTGTCTCTTCTCAGCTTTCTGTGGTGTTCTGTGGTTCCTCCTGC
TCAGCATATTTATAGACTCCAACTTTTCCTTCCCACTCTGGTCTAGTGATCCTCAGTTGTTGCCTGAATCATTGCAGAAGCCTCTCAGCC
TGGCTCCCTCCTTCCTTCTTTGGCCCTCAACTGCATTTGGAATGTGCCTTTAGAGCCTGCGTTAGCACATGTCACTTTTGCAAAAATCCT
CCAGTGATTCTCATTTCACTCAGCATCACAGCCTGTGTCCTGCCATGGTCCATAAGATCTGCTCCCTCCGTACTTCTTTGATGCTATGTT

>54491_54491_5_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263329_ENST00000541332_length(amino acids)=251AA_BP=37
MSPVPFAFPLLSWPTPLRGLATAEPAACPAANMSFLFFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKII
RRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLA

--------------------------------------------------------------
>54491_54491_6_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263330_ENST00000369073_length(transcript)=1324nt_BP=215nt
GAGCGCTACCCACTTCCGCCCCCTCCCCCTGCCATTGGAACTAGCTGAGCCGAACTAGTTGCGGCCACCGAGCAGCCGGCTCTCGGCACC
TCCTCCTCCGCCTCCCTGTCTCCTGTTCCATTCGCCTTTCCTCTTCTTTCCTGGCCCACGCCGCTCCGAGGCCTCGCGACCGCCGAGCCT
GCAGCCTGCCCCGCGGCCAACATGAGCTTCTTGTTTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGG
CTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGTTATTTGT
GTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGCTCTTGCTTTGAATGGAGTCTGC
ACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGGAGTGATGAACTCGGAAATGCAT
TGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGCCTTTTCGGGCCTTGGCTTCACG
ACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTAC
TGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTT
GCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGCCTCACTG
AAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTCCTGGGAG
GATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCAGTTGTTT
CTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTTGCAAGTG
AAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAATGTTTGCT

>54491_54491_6_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263330_ENST00000369073_length(amino acids)=289AA_BP=37
MSPVPFAFPLLSWPTPLRGLATAEPAACPAANMSFLFFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKII
RRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLA
GKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEER

--------------------------------------------------------------
>54491_54491_7_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263330_ENST00000398248_length(transcript)=877nt_BP=215nt
GAGCGCTACCCACTTCCGCCCCCTCCCCCTGCCATTGGAACTAGCTGAGCCGAACTAGTTGCGGCCACCGAGCAGCCGGCTCTCGGCACC
TCCTCCTCCGCCTCCCTGTCTCCTGTTCCATTCGCCTTTCCTCTTCTTTCCTGGCCCACGCCGCTCCGAGGCCTCGCGACCGCCGAGCCT
GCAGCCTGCCCCGCGGCCAACATGAGCTTCTTGTTTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGG
CTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTATTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTTG
CATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGCCTCACTGA
AGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTCCTGGGAGG
ATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCAGTTGTTTC
TCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTTGCAAGTGA
AGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAATGTTTGCTG

>54491_54491_7_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263330_ENST00000398248_length(amino acids)=114AA_BP=37
MSPVPFAFPLLSWPTPLRGLATAEPAACPAANMSFLFFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFIPLWVESSASFLHTFAT

--------------------------------------------------------------
>54491_54491_8_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263330_ENST00000398250_length(transcript)=1328nt_BP=215nt
GAGCGCTACCCACTTCCGCCCCCTCCCCCTGCCATTGGAACTAGCTGAGCCGAACTAGTTGCGGCCACCGAGCAGCCGGCTCTCGGCACC
TCCTCCTCCGCCTCCCTGTCTCCTGTTCCATTCGCCTTTCCTCTTCTTTCCTGGCCCACGCCGCTCCGAGGCCTCGCGACCGCCGAGCCT
GCAGCCTGCCCCGCGGCCAACATGAGCTTCTTGTTTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGG
CTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGTTATTTGT
GTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGCTCTTGCTTTGAATGGAGTCTGC
ACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGGAGTGATGAACTCGGAAATGCAT
TGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGCCTTTTCGGGCCTTGGCTTCACG
ACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTAC
TGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTT
GCATACATTTGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGCCTCACTG
AAGAAAGAGGAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTCCTGGGAG
GATGGACACTAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCAGTTGTTT
CTCAAAGTCATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTTGCAAGTG
AAGGACAACAATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAATGTTTGCT

>54491_54491_8_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263330_ENST00000398250_length(amino acids)=289AA_BP=37
MSPVPFAFPLLSWPTPLRGLATAEPAACPAANMSFLFFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKII
RRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLA
GKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQHYPPLANTACHKPYVSLRVPASLKKEER

--------------------------------------------------------------
>54491_54491_9_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263330_ENST00000439221_length(transcript)=1139nt_BP=215nt
GAGCGCTACCCACTTCCGCCCCCTCCCCCTGCCATTGGAACTAGCTGAGCCGAACTAGTTGCGGCCACCGAGCAGCCGGCTCTCGGCACC
TCCTCCTCCGCCTCCCTGTCTCCTGTTCCATTCGCCTTTCCTCTTCTTTCCTGGCCCACGCCGCTCCGAGGCCTCGCGACCGCCGAGCCT
GCAGCCTGCCCCGCGGCCAACATGAGCTTCTTGTTTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGG
CTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGTTATTTGT
GTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGTTGCCTTTTCGGGCCTTGGCTTCACGACGTTCTAC
TTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTACTGCGCCATG
ATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGATTCCTTTGTGGGTGGAGTCATCGGCCTCATTTTTGCATACATT
TGCTACAGACAGCACTATCCTCCTCTGGCCAACACAGCTTGCCATAAACCCTACGTTAGTCTGCGAGTCCCAGCCTCACTGAAGAAAGAG
GAGAGGCCCACAGCTGACAGCGCACCCAGCTTGCCTCTGGAGGGGATCACCGAAGGCCCGGTATGACCAGTGTCCTGGGAGGATGGACAC
TAAGCCCTGGGCACATCTGCCACCCTGACATCATAACACAATAGAAATGGTTTTCTGTAGTGTATTTTTCATCAGTTGTTTCTCAAAGTC
ATCGTACTTCTGCTTCTGTTTCACTGATGGTGTTCCTGCTACTTTAAATGTCTACTTCCAACATCCTTGAATTTGCAAGTGAAGGACAAC
AATCTCTGAGAGACGTGTGGAAGAGGCTGTGAAGGTGGGGTTTGGGGAGCTTGGCCGATTCGTCTATCTGAAATGTTTGCTGTAACAGCC

>54491_54491_9_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263330_ENST00000439221_length(amino acids)=226AA_BP=37
MSPVPFAFPLLSWPTPLRGLATAEPAACPAANMSFLFFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKII
RRTDKTEIKEAFLVAFSGLGFTTFYLAGKLHCFTESGRGKSWRLCAAILPLYCAMMIALSRMCDYKHHWQDSFVGGVIGLIFAYICYRQH

--------------------------------------------------------------
>54491_54491_10_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263330_ENST00000541332_length(transcript)=1524nt_BP=215nt
GAGCGCTACCCACTTCCGCCCCCTCCCCCTGCCATTGGAACTAGCTGAGCCGAACTAGTTGCGGCCACCGAGCAGCCGGCTCTCGGCACC
TCCTCCTCCGCCTCCCTGTCTCCTGTTCCATTCGCCTTTCCTCTTCTTTCCTGGCCCACGCCGCTCCGAGGCCTCGCGACCGCCGAGCCT
GCAGCCTGCCCCGCGGCCAACATGAGCTTCTTGTTTTTTACAGAGTTTTTGGATCCGTTCCAGAGAGTCATCCAGCCAGAAGAGATCTGG
CTCTATAAAAATCCTTTGGTGCAATCAGATAACATACCTACCCGCCTCATGTTTGCAATTTCTTTCCTCACACCCCTGGCTGTTATTTGT
GTGGTGAAAATTATCCGGCGAACAGACAAGACTGAAATTAAGGAAGCCTTCTTAGCGGTGTCCTTGGCTCTTGCTTTGAATGGAGTCTGC
ACAAACACTATTAAATTAATAGTGGGAAGACCTCGCCCCGATTTCTTTTACCGCTGCTTTCCAGATGGAGTGATGAACTCGGAAATGCAT
TGCACAGGTGACCCCGATCTGGTGTCCGAGGGCCGCAAAAGCTTCCCCAGCATCCATTCCTCCTTTGCCTTTTCGGGCCTTGGCTTCACG
ACGTTCTACTTGGCGGGCAAGCTGCACTGCTTCACCGAGAGTGGGCGGGGAAAGAGCTGGCGGCTCTGTGCTGCCATCCTGCCCTTGTAC
TGCGCCATGATGATTGCCCTGTCCCGCATGTGCGACTACAAGCATCACTGGCAAGTTGGCTGCTGTGTATGGCAGGGCCCACAGTCACAT
TTACCATCGGCTGCCAACCCCCGCCTCTGTCTGGGAACCTCTGAACCTTGACTGCCCATCTAAGTCCACCCGCCTCTGTGTTGGTGCCTA
GGAGAGCGTAAGAAGCCTCAGCCCCTGGCTCACCCCTCCCTCCGGTCAAAGTCCACTGCATATCCTGCTTTCAGCCTCAAGAGAGGCATT
CTCAGTCAGGACTTCTGCCCTCTTCCTGCCTCCAGGATAGCCCTGGTGTTTCCCCGTGATGTAATTCCCAGGGAAGATGGACGTTGATTG
CTCCCAAGTCTCACTGGCATCCTTCCTTTGTTTTACTCAAGGGAACCTGTCTCTTCTCAGCTTTCTGTGGTGTTCTGTGGTTCCTCCTGC
TCAGCATATTTATAGACTCCAACTTTTCCTTCCCACTCTGGTCTAGTGATCCTCAGTTGTTGCCTGAATCATTGCAGAAGCCTCTCAGCC
TGGCTCCCTCCTTCCTTCTTTGGCCCTCAACTGCATTTGGAATGTGCCTTTAGAGCCTGCGTTAGCACATGTCACTTTTGCAAAAATCCT
CCAGTGATTCTCATTTCACTCAGCATCACAGCCTGTGTCCTGCCATGGTCCATAAGATCTGCTCCCTCCGTACTTCTTTGATGCTATGTT

>54491_54491_10_MOB1B-PPAPDC1A_MOB1B_chr4_71768267_ENST00000309395_PPAPDC1A_chr10_122263330_ENST00000541332_length(amino acids)=251AA_BP=37
MSPVPFAFPLLSWPTPLRGLATAEPAACPAANMSFLFFTEFLDPFQRVIQPEEIWLYKNPLVQSDNIPTRLMFAISFLTPLAVICVVKII
RRTDKTEIKEAFLAVSLALALNGVCTNTIKLIVGRPRPDFFYRCFPDGVMNSEMHCTGDPDLVSEGRKSFPSIHSSFAFSGLGFTTFYLA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MOB1B-PPAPDC1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MOB1B-PPAPDC1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MOB1B-PPAPDC1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource