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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MON2-CHGB (FusionGDB2 ID:54569)

Fusion Gene Summary for MON2-CHGB

check button Fusion gene summary
Fusion gene informationFusion gene name: MON2-CHGB
Fusion gene ID: 54569
HgeneTgene
Gene symbol

MON2

CHGB

Gene ID

23041

1114

Gene nameMON2 homolog, regulator of endosome-to-Golgi traffickingchromogranin B
Synonyms-SCG1
Cytomap

12q14.1

20p12.3

Type of geneprotein-codingprotein-coding
Descriptionprotein MON2 homologMON2 regulator of endosome-to-Golgi traffickingsecretogranin-1cgBsecretogranin Bsecretogranin IsgI
Modification date2020031320200313
UniProtAcc

Q7Z3U7

P05060

Ensembl transtripts involved in fusion geneENST00000280379, ENST00000393629, 
ENST00000393630, ENST00000393632, 
ENST00000546600, ENST00000552115, 
ENST00000552738, ENST00000549378, 
ENST00000551397, 		ENST00000488832, 
ENST00000378961, 
Fusion gene scores* DoF score18 X 13 X 7=16388 X 11 X 4=352
# samples 1910
** MAII scorelog2(19/1638*10)=-3.10786403331006
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/352*10)=-1.81557542886257
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MON2 [Title/Abstract] AND CHGB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMON2(62926331)-CHGB(5904344), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MON2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CHGB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABC042679MON2chr12

62926331

+CHGBchr20

5904344

+


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Fusion Gene ORF analysis for MON2-CHGB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000280379ENST00000488832MON2chr12

62926331

+CHGBchr20

5904344

+
5CDS-intronENST00000393629ENST00000488832MON2chr12

62926331

+CHGBchr20

5904344

+
5CDS-intronENST00000393630ENST00000488832MON2chr12

62926331

+CHGBchr20

5904344

+
5CDS-intronENST00000393632ENST00000488832MON2chr12

62926331

+CHGBchr20

5904344

+
5CDS-intronENST00000546600ENST00000488832MON2chr12

62926331

+CHGBchr20

5904344

+
5CDS-intronENST00000552115ENST00000488832MON2chr12

62926331

+CHGBchr20

5904344

+
5CDS-intronENST00000552738ENST00000488832MON2chr12

62926331

+CHGBchr20

5904344

+
In-frameENST00000280379ENST00000378961MON2chr12

62926331

+CHGBchr20

5904344

+
In-frameENST00000393629ENST00000378961MON2chr12

62926331

+CHGBchr20

5904344

+
In-frameENST00000393630ENST00000378961MON2chr12

62926331

+CHGBchr20

5904344

+
In-frameENST00000393632ENST00000378961MON2chr12

62926331

+CHGBchr20

5904344

+
In-frameENST00000546600ENST00000378961MON2chr12

62926331

+CHGBchr20

5904344

+
In-frameENST00000552115ENST00000378961MON2chr12

62926331

+CHGBchr20

5904344

+
In-frameENST00000552738ENST00000378961MON2chr12

62926331

+CHGBchr20

5904344

+
intron-3CDSENST00000549378ENST00000378961MON2chr12

62926331

+CHGBchr20

5904344

+
intron-3CDSENST00000551397ENST00000378961MON2chr12

62926331

+CHGBchr20

5904344

+
intron-intronENST00000549378ENST00000488832MON2chr12

62926331

+CHGBchr20

5904344

+
intron-intronENST00000551397ENST00000488832MON2chr12

62926331

+CHGBchr20

5904344

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000280379MON2chr1262926331+ENST00000378961CHGBchr205904344+270219103491791480
ENST00000393632MON2chr1262926331+ENST00000378961CHGBchr205904344+270219103491791480
ENST00000393630MON2chr1262926331+ENST00000378961CHGBchr205904344+270219103491791480
ENST00000546600MON2chr1262926331+ENST00000378961CHGBchr205904344+269719053441786480
ENST00000552738MON2chr1262926331+ENST00000378961CHGBchr205904344+267118793181760480
ENST00000393629MON2chr1262926331+ENST00000378961CHGBchr205904344+267118793181760480
ENST00000552115MON2chr1262926331+ENST00000378961CHGBchr205904344+267018783171759480

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000280379ENST00000378961MON2chr1262926331+CHGBchr205904344+0.0018433880.9981566
ENST00000393632ENST00000378961MON2chr1262926331+CHGBchr205904344+0.0018433880.9981566
ENST00000393630ENST00000378961MON2chr1262926331+CHGBchr205904344+0.0018433880.9981566
ENST00000546600ENST00000378961MON2chr1262926331+CHGBchr205904344+0.0019311250.99806887
ENST00000552738ENST00000378961MON2chr1262926331+CHGBchr205904344+0.0017730080.99822706
ENST00000393629ENST00000378961MON2chr1262926331+CHGBchr205904344+0.0017730080.99822706
ENST00000552115ENST00000378961MON2chr1262926331+CHGBchr205904344+0.001795970.998204

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Fusion Genomic Features for MON2-CHGB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MON2-CHGB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:62926331/chr20:5904344)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MON2

Q7Z3U7

CHGB

P05060

FUNCTION: Plays a role in regulating membrane trafficking of cargo proteins. Together with ATP9A and DOP1B, regulates SNX3 retromer-mediated endosomal sorting of WLS away from lysosomal degradation. {ECO:0000269|PubMed:30213940}.FUNCTION: Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCHGBchr12:62926331chr20:5904344ENST0000037896105163_1710678.0Compositional biasNote=Poly-Glu
TgeneCHGBchr12:62926331chr20:5904344ENST0000037896105116_1200678.0RegionNote=O-glycosylated at one site

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for MON2-CHGB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>54569_54569_1_MON2-CHGB_MON2_chr12_62926331_ENST00000280379_CHGB_chr20_5904344_ENST00000378961_length(transcript)=2702nt_BP=1910nt
ATTGTGGGCGACTCGGCTAATGGCGTCGGCGAGTCTTAGGGGCCTGGGGAGCTGGCGCTGAAGCTTCTTGCCAGGTTGGCTGGTGACACC
CGGTGTGGCTGGGCCCCGCGGCAGCGGAGGGACCTGCCCGCCTTGTGGGTTTCTCGGCCAGAGTCGGCGGAGCCTAGCGGGACGGTGCGA
CTGCGGGGGGCGCCTCCGAGAAAAGCCAGAGGTGTTGCGGGGAAGCTGCTGGGGGACGCTCGAGCAGGCTCCGGGTTCGCAGCCCAGGGC
CCAAGAAGCGGGCTGCTGAAGGACCAGAGACACCGGGAGGGAGCTGCCTGTGGCCCTAAGGAGCTGACCGTGCCAGAGCTTGTTTGTACC
TCTCGGAAATTGGCTGGGACCTTGGAGGATCATGTCCGGCACCAGCAGCCCCGAGGCGGTGAAGAAGCTGCTGGAGAATATGCAGAGCGA
CTTGCGCGCCTTGTCACTGGAGTGCAAGAAGAAATTCCCACCTGTCAAAGAGGCTGCTGAATCAGGAATAATAAAAGTTAAAACAATTGC
TGCACGAAACACTGAAATTTTGGCAGCACTGAAAGAGAACAGCTCAGAGGTTGTACAGCCTTTTTTAATGGGTTGTGGAACCAAGGAACC
GAAGATCACTCAGCTATGTTTGGCTGCTATTCAGAGACTCATGTCACATGAAGTCGTGTCTGAGACTGCAGCTGGAAATATAATTAACAT
GCTTTGGCAGCTAATGGAGAATAGTCTTGAAGAACTTAAGCTACTTCAAACAGTTCTTGTTCTTTTAACAACCAATACAGTAGTTCATGA
TGAGGCACTTTCTAAGGCAATCGTTCTTTGTTTTCGACTACACTTCACAAAAGATAATATTACAAATAATACAGCTGCTGCTACAGTGCG
ACAAGTTGTTACTGTTGTTTTTGAGAGGATGGTTGCTGAAGATGAACGACACAGAGATATTATAGAACAACCAGTACTGGTACAAGGAAA
TAGTAACAGAAGATCTGTCAGTACCCTCAAACCTTGTGCTAAAGATGCATATATGCTTTTCCAGGATCTTTGTCAGTTGGTTAATGCTGA
TGCTCCTTATTGGCTAGTGGGCATGACAGAAATGACTCGGACGTTTGGCCTCGAATTACTTGAGTCAGTCCTCAATGATTTTCCGCAGGT
CTTTTTACAACACCAAGAATTTAGTTTCCTCCTCAAAGAAAGGGTATGTCCTCTTGTGATAAAGCTCTTTTCTCCAAATATAAAGTTCAG
ACAAGGTTCCAGCACCTCATCTTCTCCAGCACCAGTTGAAAAACCATATTTTCCTATCTGCATGCGTTTGCTGAGAGTAGTATCTGTTCT
GATTAAGCAGTTTTACAGTCTTTTGGTAACTGAATGTGAGATATTTCTGTCACTTCTGGTGAAATTTCTGGATGCAGATAAACCACAGTG
GCTACGAGCTGTTGCGGTGGAATCAATACACAGATTCTGTGTGCAGCCTCAACTATTAAGGTCATTTTGTCAGTCCTATGATATGAAACA
GCATTCTACCAAGGTTTTTCGTGATATTGTAAATGCACTGGGATCTTTTATACAGTCCTTGTTTCTTGTCCCCCCTACTGGAAATCCTGC
AACAAGCAACCAAGCTGGAAACAATAATTTAGGTGGCTCAGTCTCAGCACCAGCTAACTCAGGAATGGTGGGGATTGGTGGAGGTGTTAC
TTTGCTACCAGCATTTGAATATAGGGGAACCTGGATACCTATTCTGACAATCACAGTTCAAGGCAGTGCTAAAGCCACCTAAGAGCTAGG
AGAGCTTGAAACAGAATGTCAAACCACCACTGAAGAAGGTTCTTCACCAACACAGTCGACAGAACAGCAGGATTTACAGTCAACATCAGA
CCAAATGGATAAGGAAATTGGGGGAACTGTTCAACCCATACTACGACCCTCTCCAGTGGAAGAGCAGCCATTTTGAAAGAAGAGACAACA
TGAATGACAATTTTCTCGAGGGTGAGGAGGAAAATGAGCTGACCTTGAACGAGAAGAATTTCTTCCCAGAATACAACTATGACTGGTGGG
AGAAAAAGCCCTTCTCTGAGGATGTGAACTGGGGGTATGAGAAGAGAAACCTCGCCAGGGTCCCCAAGCTGGACCTGAAAAGGCAATATG
ACAGGGTGGCCCAACTGGACCAGCTCCTTCACTACAGGAAGAAGTCAGCTGAGTTTCCAGACTTCTATGATTCTGAGGAGCCGGTGAGCA
CCCACCAGGAGGCAGAAAATGAAAAGGACAGGGCTGACCAGACAGTCCTGACAGAGGACGAGAAAAAAGAACTCGAAAACTTGGCTGCAA
TGGATTTGGAACTACAGAAGATAGCTGAGAAATTCAGCCAAAGGGGCTGACTGTCATTGGAGCGGTGGGCACTGTTAAGAAGCAGCCATC
ACATGATCTGTTTTTCACCACTTCACTGAAAGACACCATTTATCTACCCAAGGGCAGAAAGTAGAACTTACTATTCATTAAATGTTTGAC
ACAATTGGAATTGTCTTTAATTTCTGTCAGAATGCTATTGAAAATGTGAATTGCATGACTTGTAGCATATTCTTTTCTGCAAAATAGACA
TATTAACATGCTTATGACAATGACTGTGCTACTGTCTTTGGAAAAATGTTTGTCTCAGTTGGAAATAATAAAAGATTCACCTGAGACCAA

>54569_54569_1_MON2-CHGB_MON2_chr12_62926331_ENST00000280379_CHGB_chr20_5904344_ENST00000378961_length(amino acids)=480AA_BP=
MFVPLGNWLGPWRIMSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCG
TKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAA
ATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLND
FPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDAD
KPQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPATSNQAGNNNLGGSVSAPANSGMVGIG

--------------------------------------------------------------
>54569_54569_2_MON2-CHGB_MON2_chr12_62926331_ENST00000393629_CHGB_chr20_5904344_ENST00000378961_length(transcript)=2671nt_BP=1879nt
AGTCTTAGGGGCCTGGGGAGCTGGCGCTGAAGCTTCTTGCCAGGTTGGCTGGTGACACCCGGTGTGGCTGGGCCCCGCGGCAGCGGAGGG
ACCTGCCCGCCTTGTGGGTTTCTCGGCCAGAGTCGGCGGAGCCTAGCGGGACGGTGCGACTGCGGGGGGCGCCTCCGAGAAAAGCCAGAG
GTGTTGCGGGGAAGCTGCTGGGGGACGCTCGAGCAGGCTCCGGGTTCGCAGCCCAGGGCCCAAGAAGCGGGCTGCTGAAGGACCAGAGAC
ACCGGGAGGGAGCTGCCTGTGGCCCTAAGGAGCTGACCGTGCCAGAGCTTGTTTGTACCTCTCGGAAATTGGCTGGGACCTTGGAGGATC
ATGTCCGGCACCAGCAGCCCCGAGGCGGTGAAGAAGCTGCTGGAGAATATGCAGAGCGACTTGCGCGCCTTGTCACTGGAGTGCAAGAAG
AAATTCCCACCTGTCAAAGAGGCTGCTGAATCAGGAATAATAAAAGTTAAAACAATTGCTGCACGAAACACTGAAATTTTGGCAGCACTG
AAAGAGAACAGCTCAGAGGTTGTACAGCCTTTTTTAATGGGTTGTGGAACCAAGGAACCGAAGATCACTCAGCTATGTTTGGCTGCTATT
CAGAGACTCATGTCACATGAAGTCGTGTCTGAGACTGCAGCTGGAAATATAATTAACATGCTTTGGCAGCTAATGGAGAATAGTCTTGAA
GAACTTAAGCTACTTCAAACAGTTCTTGTTCTTTTAACAACCAATACAGTAGTTCATGATGAGGCACTTTCTAAGGCAATCGTTCTTTGT
TTTCGACTACACTTCACAAAAGATAATATTACAAATAATACAGCTGCTGCTACAGTGCGACAAGTTGTTACTGTTGTTTTTGAGAGGATG
GTTGCTGAAGATGAACGACACAGAGATATTATAGAACAACCAGTACTGGTACAAGGAAATAGTAACAGAAGATCTGTCAGTACCCTCAAA
CCTTGTGCTAAAGATGCATATATGCTTTTCCAGGATCTTTGTCAGTTGGTTAATGCTGATGCTCCTTATTGGCTAGTGGGCATGACAGAA
ATGACTCGGACGTTTGGCCTCGAATTACTTGAGTCAGTCCTCAATGATTTTCCGCAGGTCTTTTTACAACACCAAGAATTTAGTTTCCTC
CTCAAAGAAAGGGTATGTCCTCTTGTGATAAAGCTCTTTTCTCCAAATATAAAGTTCAGACAAGGTTCCAGCACCTCATCTTCTCCAGCA
CCAGTTGAAAAACCATATTTTCCTATCTGCATGCGTTTGCTGAGAGTAGTATCTGTTCTGATTAAGCAGTTTTACAGTCTTTTGGTAACT
GAATGTGAGATATTTCTGTCACTTCTGGTGAAATTTCTGGATGCAGATAAACCACAGTGGCTACGAGCTGTTGCGGTGGAATCAATACAC
AGATTCTGTGTGCAGCCTCAACTATTAAGGTCATTTTGTCAGTCCTATGATATGAAACAGCATTCTACCAAGGTTTTTCGTGATATTGTA
AATGCACTGGGATCTTTTATACAGTCCTTGTTTCTTGTCCCCCCTACTGGAAATCCTGCAACAAGCAACCAAGCTGGAAACAATAATTTA
GGTGGCTCAGTCTCAGCACCAGCTAACTCAGGAATGGTGGGGATTGGTGGAGGTGTTACTTTGCTACCAGCATTTGAATATAGGGGAACC
TGGATACCTATTCTGACAATCACAGTTCAAGGCAGTGCTAAAGCCACCTAAGAGCTAGGAGAGCTTGAAACAGAATGTCAAACCACCACT
GAAGAAGGTTCTTCACCAACACAGTCGACAGAACAGCAGGATTTACAGTCAACATCAGACCAAATGGATAAGGAAATTGGGGGAACTGTT
CAACCCATACTACGACCCTCTCCAGTGGAAGAGCAGCCATTTTGAAAGAAGAGACAACATGAATGACAATTTTCTCGAGGGTGAGGAGGA
AAATGAGCTGACCTTGAACGAGAAGAATTTCTTCCCAGAATACAACTATGACTGGTGGGAGAAAAAGCCCTTCTCTGAGGATGTGAACTG
GGGGTATGAGAAGAGAAACCTCGCCAGGGTCCCCAAGCTGGACCTGAAAAGGCAATATGACAGGGTGGCCCAACTGGACCAGCTCCTTCA
CTACAGGAAGAAGTCAGCTGAGTTTCCAGACTTCTATGATTCTGAGGAGCCGGTGAGCACCCACCAGGAGGCAGAAAATGAAAAGGACAG
GGCTGACCAGACAGTCCTGACAGAGGACGAGAAAAAAGAACTCGAAAACTTGGCTGCAATGGATTTGGAACTACAGAAGATAGCTGAGAA
ATTCAGCCAAAGGGGCTGACTGTCATTGGAGCGGTGGGCACTGTTAAGAAGCAGCCATCACATGATCTGTTTTTCACCACTTCACTGAAA
GACACCATTTATCTACCCAAGGGCAGAAAGTAGAACTTACTATTCATTAAATGTTTGACACAATTGGAATTGTCTTTAATTTCTGTCAGA
ATGCTATTGAAAATGTGAATTGCATGACTTGTAGCATATTCTTTTCTGCAAAATAGACATATTAACATGCTTATGACAATGACTGTGCTA

>54569_54569_2_MON2-CHGB_MON2_chr12_62926331_ENST00000393629_CHGB_chr20_5904344_ENST00000378961_length(amino acids)=480AA_BP=
MFVPLGNWLGPWRIMSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCG
TKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAA
ATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLND
FPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDAD
KPQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPATSNQAGNNNLGGSVSAPANSGMVGIG

--------------------------------------------------------------
>54569_54569_3_MON2-CHGB_MON2_chr12_62926331_ENST00000393630_CHGB_chr20_5904344_ENST00000378961_length(transcript)=2702nt_BP=1910nt
ATTGTGGGCGACTCGGCTAATGGCGTCGGCGAGTCTTAGGGGCCTGGGGAGCTGGCGCTGAAGCTTCTTGCCAGGTTGGCTGGTGACACC
CGGTGTGGCTGGGCCCCGCGGCAGCGGAGGGACCTGCCCGCCTTGTGGGTTTCTCGGCCAGAGTCGGCGGAGCCTAGCGGGACGGTGCGA
CTGCGGGGGGCGCCTCCGAGAAAAGCCAGAGGTGTTGCGGGGAAGCTGCTGGGGGACGCTCGAGCAGGCTCCGGGTTCGCAGCCCAGGGC
CCAAGAAGCGGGCTGCTGAAGGACCAGAGACACCGGGAGGGAGCTGCCTGTGGCCCTAAGGAGCTGACCGTGCCAGAGCTTGTTTGTACC
TCTCGGAAATTGGCTGGGACCTTGGAGGATCATGTCCGGCACCAGCAGCCCCGAGGCGGTGAAGAAGCTGCTGGAGAATATGCAGAGCGA
CTTGCGCGCCTTGTCACTGGAGTGCAAGAAGAAATTCCCACCTGTCAAAGAGGCTGCTGAATCAGGAATAATAAAAGTTAAAACAATTGC
TGCACGAAACACTGAAATTTTGGCAGCACTGAAAGAGAACAGCTCAGAGGTTGTACAGCCTTTTTTAATGGGTTGTGGAACCAAGGAACC
GAAGATCACTCAGCTATGTTTGGCTGCTATTCAGAGACTCATGTCACATGAAGTCGTGTCTGAGACTGCAGCTGGAAATATAATTAACAT
GCTTTGGCAGCTAATGGAGAATAGTCTTGAAGAACTTAAGCTACTTCAAACAGTTCTTGTTCTTTTAACAACCAATACAGTAGTTCATGA
TGAGGCACTTTCTAAGGCAATCGTTCTTTGTTTTCGACTACACTTCACAAAAGATAATATTACAAATAATACAGCTGCTGCTACAGTGCG
ACAAGTTGTTACTGTTGTTTTTGAGAGGATGGTTGCTGAAGATGAACGACACAGAGATATTATAGAACAACCAGTACTGGTACAAGGAAA
TAGTAACAGAAGATCTGTCAGTACCCTCAAACCTTGTGCTAAAGATGCATATATGCTTTTCCAGGATCTTTGTCAGTTGGTTAATGCTGA
TGCTCCTTATTGGCTAGTGGGCATGACAGAAATGACTCGGACGTTTGGCCTCGAATTACTTGAGTCAGTCCTCAATGATTTTCCGCAGGT
CTTTTTACAACACCAAGAATTTAGTTTCCTCCTCAAAGAAAGGGTATGTCCTCTTGTGATAAAGCTCTTTTCTCCAAATATAAAGTTCAG
ACAAGGTTCCAGCACCTCATCTTCTCCAGCACCAGTTGAAAAACCATATTTTCCTATCTGCATGCGTTTGCTGAGAGTAGTATCTGTTCT
GATTAAGCAGTTTTACAGTCTTTTGGTAACTGAATGTGAGATATTTCTGTCACTTCTGGTGAAATTTCTGGATGCAGATAAACCACAGTG
GCTACGAGCTGTTGCGGTGGAATCAATACACAGATTCTGTGTGCAGCCTCAACTATTAAGGTCATTTTGTCAGTCCTATGATATGAAACA
GCATTCTACCAAGGTTTTTCGTGATATTGTAAATGCACTGGGATCTTTTATACAGTCCTTGTTTCTTGTCCCCCCTACTGGAAATCCTGC
AACAAGCAACCAAGCTGGAAACAATAATTTAGGTGGCTCAGTCTCAGCACCAGCTAACTCAGGAATGGTGGGGATTGGTGGAGGTGTTAC
TTTGCTACCAGCATTTGAATATAGGGGAACCTGGATACCTATTCTGACAATCACAGTTCAAGGCAGTGCTAAAGCCACCTAAGAGCTAGG
AGAGCTTGAAACAGAATGTCAAACCACCACTGAAGAAGGTTCTTCACCAACACAGTCGACAGAACAGCAGGATTTACAGTCAACATCAGA
CCAAATGGATAAGGAAATTGGGGGAACTGTTCAACCCATACTACGACCCTCTCCAGTGGAAGAGCAGCCATTTTGAAAGAAGAGACAACA
TGAATGACAATTTTCTCGAGGGTGAGGAGGAAAATGAGCTGACCTTGAACGAGAAGAATTTCTTCCCAGAATACAACTATGACTGGTGGG
AGAAAAAGCCCTTCTCTGAGGATGTGAACTGGGGGTATGAGAAGAGAAACCTCGCCAGGGTCCCCAAGCTGGACCTGAAAAGGCAATATG
ACAGGGTGGCCCAACTGGACCAGCTCCTTCACTACAGGAAGAAGTCAGCTGAGTTTCCAGACTTCTATGATTCTGAGGAGCCGGTGAGCA
CCCACCAGGAGGCAGAAAATGAAAAGGACAGGGCTGACCAGACAGTCCTGACAGAGGACGAGAAAAAAGAACTCGAAAACTTGGCTGCAA
TGGATTTGGAACTACAGAAGATAGCTGAGAAATTCAGCCAAAGGGGCTGACTGTCATTGGAGCGGTGGGCACTGTTAAGAAGCAGCCATC
ACATGATCTGTTTTTCACCACTTCACTGAAAGACACCATTTATCTACCCAAGGGCAGAAAGTAGAACTTACTATTCATTAAATGTTTGAC
ACAATTGGAATTGTCTTTAATTTCTGTCAGAATGCTATTGAAAATGTGAATTGCATGACTTGTAGCATATTCTTTTCTGCAAAATAGACA
TATTAACATGCTTATGACAATGACTGTGCTACTGTCTTTGGAAAAATGTTTGTCTCAGTTGGAAATAATAAAAGATTCACCTGAGACCAA

>54569_54569_3_MON2-CHGB_MON2_chr12_62926331_ENST00000393630_CHGB_chr20_5904344_ENST00000378961_length(amino acids)=480AA_BP=
MFVPLGNWLGPWRIMSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCG
TKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAA
ATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLND
FPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDAD
KPQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPATSNQAGNNNLGGSVSAPANSGMVGIG

--------------------------------------------------------------
>54569_54569_4_MON2-CHGB_MON2_chr12_62926331_ENST00000393632_CHGB_chr20_5904344_ENST00000378961_length(transcript)=2702nt_BP=1910nt
ATTGTGGGCGACTCGGCTAATGGCGTCGGCGAGTCTTAGGGGCCTGGGGAGCTGGCGCTGAAGCTTCTTGCCAGGTTGGCTGGTGACACC
CGGTGTGGCTGGGCCCCGCGGCAGCGGAGGGACCTGCCCGCCTTGTGGGTTTCTCGGCCAGAGTCGGCGGAGCCTAGCGGGACGGTGCGA
CTGCGGGGGGCGCCTCCGAGAAAAGCCAGAGGTGTTGCGGGGAAGCTGCTGGGGGACGCTCGAGCAGGCTCCGGGTTCGCAGCCCAGGGC
CCAAGAAGCGGGCTGCTGAAGGACCAGAGACACCGGGAGGGAGCTGCCTGTGGCCCTAAGGAGCTGACCGTGCCAGAGCTTGTTTGTACC
TCTCGGAAATTGGCTGGGACCTTGGAGGATCATGTCCGGCACCAGCAGCCCCGAGGCGGTGAAGAAGCTGCTGGAGAATATGCAGAGCGA
CTTGCGCGCCTTGTCACTGGAGTGCAAGAAGAAATTCCCACCTGTCAAAGAGGCTGCTGAATCAGGAATAATAAAAGTTAAAACAATTGC
TGCACGAAACACTGAAATTTTGGCAGCACTGAAAGAGAACAGCTCAGAGGTTGTACAGCCTTTTTTAATGGGTTGTGGAACCAAGGAACC
GAAGATCACTCAGCTATGTTTGGCTGCTATTCAGAGACTCATGTCACATGAAGTCGTGTCTGAGACTGCAGCTGGAAATATAATTAACAT
GCTTTGGCAGCTAATGGAGAATAGTCTTGAAGAACTTAAGCTACTTCAAACAGTTCTTGTTCTTTTAACAACCAATACAGTAGTTCATGA
TGAGGCACTTTCTAAGGCAATCGTTCTTTGTTTTCGACTACACTTCACAAAAGATAATATTACAAATAATACAGCTGCTGCTACAGTGCG
ACAAGTTGTTACTGTTGTTTTTGAGAGGATGGTTGCTGAAGATGAACGACACAGAGATATTATAGAACAACCAGTACTGGTACAAGGAAA
TAGTAACAGAAGATCTGTCAGTACCCTCAAACCTTGTGCTAAAGATGCATATATGCTTTTCCAGGATCTTTGTCAGTTGGTTAATGCTGA
TGCTCCTTATTGGCTAGTGGGCATGACAGAAATGACTCGGACGTTTGGCCTCGAATTACTTGAGTCAGTCCTCAATGATTTTCCGCAGGT
CTTTTTACAACACCAAGAATTTAGTTTCCTCCTCAAAGAAAGGGTATGTCCTCTTGTGATAAAGCTCTTTTCTCCAAATATAAAGTTCAG
ACAAGGTTCCAGCACCTCATCTTCTCCAGCACCAGTTGAAAAACCATATTTTCCTATCTGCATGCGTTTGCTGAGAGTAGTATCTGTTCT
GATTAAGCAGTTTTACAGTCTTTTGGTAACTGAATGTGAGATATTTCTGTCACTTCTGGTGAAATTTCTGGATGCAGATAAACCACAGTG
GCTACGAGCTGTTGCGGTGGAATCAATACACAGATTCTGTGTGCAGCCTCAACTATTAAGGTCATTTTGTCAGTCCTATGATATGAAACA
GCATTCTACCAAGGTTTTTCGTGATATTGTAAATGCACTGGGATCTTTTATACAGTCCTTGTTTCTTGTCCCCCCTACTGGAAATCCTGC
AACAAGCAACCAAGCTGGAAACAATAATTTAGGTGGCTCAGTCTCAGCACCAGCTAACTCAGGAATGGTGGGGATTGGTGGAGGTGTTAC
TTTGCTACCAGCATTTGAATATAGGGGAACCTGGATACCTATTCTGACAATCACAGTTCAAGGCAGTGCTAAAGCCACCTAAGAGCTAGG
AGAGCTTGAAACAGAATGTCAAACCACCACTGAAGAAGGTTCTTCACCAACACAGTCGACAGAACAGCAGGATTTACAGTCAACATCAGA
CCAAATGGATAAGGAAATTGGGGGAACTGTTCAACCCATACTACGACCCTCTCCAGTGGAAGAGCAGCCATTTTGAAAGAAGAGACAACA
TGAATGACAATTTTCTCGAGGGTGAGGAGGAAAATGAGCTGACCTTGAACGAGAAGAATTTCTTCCCAGAATACAACTATGACTGGTGGG
AGAAAAAGCCCTTCTCTGAGGATGTGAACTGGGGGTATGAGAAGAGAAACCTCGCCAGGGTCCCCAAGCTGGACCTGAAAAGGCAATATG
ACAGGGTGGCCCAACTGGACCAGCTCCTTCACTACAGGAAGAAGTCAGCTGAGTTTCCAGACTTCTATGATTCTGAGGAGCCGGTGAGCA
CCCACCAGGAGGCAGAAAATGAAAAGGACAGGGCTGACCAGACAGTCCTGACAGAGGACGAGAAAAAAGAACTCGAAAACTTGGCTGCAA
TGGATTTGGAACTACAGAAGATAGCTGAGAAATTCAGCCAAAGGGGCTGACTGTCATTGGAGCGGTGGGCACTGTTAAGAAGCAGCCATC
ACATGATCTGTTTTTCACCACTTCACTGAAAGACACCATTTATCTACCCAAGGGCAGAAAGTAGAACTTACTATTCATTAAATGTTTGAC
ACAATTGGAATTGTCTTTAATTTCTGTCAGAATGCTATTGAAAATGTGAATTGCATGACTTGTAGCATATTCTTTTCTGCAAAATAGACA
TATTAACATGCTTATGACAATGACTGTGCTACTGTCTTTGGAAAAATGTTTGTCTCAGTTGGAAATAATAAAAGATTCACCTGAGACCAA

>54569_54569_4_MON2-CHGB_MON2_chr12_62926331_ENST00000393632_CHGB_chr20_5904344_ENST00000378961_length(amino acids)=480AA_BP=
MFVPLGNWLGPWRIMSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCG
TKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAA
ATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLND
FPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDAD
KPQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPATSNQAGNNNLGGSVSAPANSGMVGIG

--------------------------------------------------------------
>54569_54569_5_MON2-CHGB_MON2_chr12_62926331_ENST00000546600_CHGB_chr20_5904344_ENST00000378961_length(transcript)=2697nt_BP=1905nt
GGGCGACTCGGCTAATGGCGTCGGCGAGTCTTAGGGGCCTGGGGAGCTGGCGCTGAAGCTTCTTGCCAGGTTGGCTGGTGACACCCGGTG
TGGCTGGGCCCCGCGGCAGCGGAGGGACCTGCCCGCCTTGTGGGTTTCTCGGCCAGAGTCGGCGGAGCCTAGCGGGACGGTGCGACTGCG
GGGGGCGCCTCCGAGAAAAGCCAGAGGTGTTGCGGGGAAGCTGCTGGGGGACGCTCGAGCAGGCTCCGGGTTCGCAGCCCAGGGCCCAAG
AAGCGGGCTGCTGAAGGACCAGAGACACCGGGAGGGAGCTGCCTGTGGCCCTAAGGAGCTGACCGTGCCAGAGCTTGTTTGTACCTCTCG
GAAATTGGCTGGGACCTTGGAGGATCATGTCCGGCACCAGCAGCCCCGAGGCGGTGAAGAAGCTGCTGGAGAATATGCAGAGCGACTTGC
GCGCCTTGTCACTGGAGTGCAAGAAGAAATTCCCACCTGTCAAAGAGGCTGCTGAATCAGGAATAATAAAAGTTAAAACAATTGCTGCAC
GAAACACTGAAATTTTGGCAGCACTGAAAGAGAACAGCTCAGAGGTTGTACAGCCTTTTTTAATGGGTTGTGGAACCAAGGAACCGAAGA
TCACTCAGCTATGTTTGGCTGCTATTCAGAGACTCATGTCACATGAAGTCGTGTCTGAGACTGCAGCTGGAAATATAATTAACATGCTTT
GGCAGCTAATGGAGAATAGTCTTGAAGAACTTAAGCTACTTCAAACAGTTCTTGTTCTTTTAACAACCAATACAGTAGTTCATGATGAGG
CACTTTCTAAGGCAATCGTTCTTTGTTTTCGACTACACTTCACAAAAGATAATATTACAAATAATACAGCTGCTGCTACAGTGCGACAAG
TTGTTACTGTTGTTTTTGAGAGGATGGTTGCTGAAGATGAACGACACAGAGATATTATAGAACAACCAGTACTGGTACAAGGAAATAGTA
ACAGAAGATCTGTCAGTACCCTCAAACCTTGTGCTAAAGATGCATATATGCTTTTCCAGGATCTTTGTCAGTTGGTTAATGCTGATGCTC
CTTATTGGCTAGTGGGCATGACAGAAATGACTCGGACGTTTGGCCTCGAATTACTTGAGTCAGTCCTCAATGATTTTCCGCAGGTCTTTT
TACAACACCAAGAATTTAGTTTCCTCCTCAAAGAAAGGGTATGTCCTCTTGTGATAAAGCTCTTTTCTCCAAATATAAAGTTCAGACAAG
GTTCCAGCACCTCATCTTCTCCAGCACCAGTTGAAAAACCATATTTTCCTATCTGCATGCGTTTGCTGAGAGTAGTATCTGTTCTGATTA
AGCAGTTTTACAGTCTTTTGGTAACTGAATGTGAGATATTTCTGTCACTTCTGGTGAAATTTCTGGATGCAGATAAACCACAGTGGCTAC
GAGCTGTTGCGGTGGAATCAATACACAGATTCTGTGTGCAGCCTCAACTATTAAGGTCATTTTGTCAGTCCTATGATATGAAACAGCATT
CTACCAAGGTTTTTCGTGATATTGTAAATGCACTGGGATCTTTTATACAGTCCTTGTTTCTTGTCCCCCCTACTGGAAATCCTGCAACAA
GCAACCAAGCTGGAAACAATAATTTAGGTGGCTCAGTCTCAGCACCAGCTAACTCAGGAATGGTGGGGATTGGTGGAGGTGTTACTTTGC
TACCAGCATTTGAATATAGGGGAACCTGGATACCTATTCTGACAATCACAGTTCAAGGCAGTGCTAAAGCCACCTAAGAGCTAGGAGAGC
TTGAAACAGAATGTCAAACCACCACTGAAGAAGGTTCTTCACCAACACAGTCGACAGAACAGCAGGATTTACAGTCAACATCAGACCAAA
TGGATAAGGAAATTGGGGGAACTGTTCAACCCATACTACGACCCTCTCCAGTGGAAGAGCAGCCATTTTGAAAGAAGAGACAACATGAAT
GACAATTTTCTCGAGGGTGAGGAGGAAAATGAGCTGACCTTGAACGAGAAGAATTTCTTCCCAGAATACAACTATGACTGGTGGGAGAAA
AAGCCCTTCTCTGAGGATGTGAACTGGGGGTATGAGAAGAGAAACCTCGCCAGGGTCCCCAAGCTGGACCTGAAAAGGCAATATGACAGG
GTGGCCCAACTGGACCAGCTCCTTCACTACAGGAAGAAGTCAGCTGAGTTTCCAGACTTCTATGATTCTGAGGAGCCGGTGAGCACCCAC
CAGGAGGCAGAAAATGAAAAGGACAGGGCTGACCAGACAGTCCTGACAGAGGACGAGAAAAAAGAACTCGAAAACTTGGCTGCAATGGAT
TTGGAACTACAGAAGATAGCTGAGAAATTCAGCCAAAGGGGCTGACTGTCATTGGAGCGGTGGGCACTGTTAAGAAGCAGCCATCACATG
ATCTGTTTTTCACCACTTCACTGAAAGACACCATTTATCTACCCAAGGGCAGAAAGTAGAACTTACTATTCATTAAATGTTTGACACAAT
TGGAATTGTCTTTAATTTCTGTCAGAATGCTATTGAAAATGTGAATTGCATGACTTGTAGCATATTCTTTTCTGCAAAATAGACATATTA

>54569_54569_5_MON2-CHGB_MON2_chr12_62926331_ENST00000546600_CHGB_chr20_5904344_ENST00000378961_length(amino acids)=480AA_BP=
MFVPLGNWLGPWRIMSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCG
TKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAA
ATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLND
FPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDAD
KPQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPATSNQAGNNNLGGSVSAPANSGMVGIG

--------------------------------------------------------------
>54569_54569_6_MON2-CHGB_MON2_chr12_62926331_ENST00000552115_CHGB_chr20_5904344_ENST00000378961_length(transcript)=2670nt_BP=1878nt
GTCTTAGGGGCCTGGGGAGCTGGCGCTGAAGCTTCTTGCCAGGTTGGCTGGTGACACCCGGTGTGGCTGGGCCCCGCGGCAGCGGAGGGA
CCTGCCCGCCTTGTGGGTTTCTCGGCCAGAGTCGGCGGAGCCTAGCGGGACGGTGCGACTGCGGGGGGCGCCTCCGAGAAAAGCCAGAGG
TGTTGCGGGGAAGCTGCTGGGGGACGCTCGAGCAGGCTCCGGGTTCGCAGCCCAGGGCCCAAGAAGCGGGCTGCTGAAGGACCAGAGACA
CCGGGAGGGAGCTGCCTGTGGCCCTAAGGAGCTGACCGTGCCAGAGCTTGTTTGTACCTCTCGGAAATTGGCTGGGACCTTGGAGGATCA
TGTCCGGCACCAGCAGCCCCGAGGCGGTGAAGAAGCTGCTGGAGAATATGCAGAGCGACTTGCGCGCCTTGTCACTGGAGTGCAAGAAGA
AATTCCCACCTGTCAAAGAGGCTGCTGAATCAGGAATAATAAAAGTTAAAACAATTGCTGCACGAAACACTGAAATTTTGGCAGCACTGA
AAGAGAACAGCTCAGAGGTTGTACAGCCTTTTTTAATGGGTTGTGGAACCAAGGAACCGAAGATCACTCAGCTATGTTTGGCTGCTATTC
AGAGACTCATGTCACATGAAGTCGTGTCTGAGACTGCAGCTGGAAATATAATTAACATGCTTTGGCAGCTAATGGAGAATAGTCTTGAAG
AACTTAAGCTACTTCAAACAGTTCTTGTTCTTTTAACAACCAATACAGTAGTTCATGATGAGGCACTTTCTAAGGCAATCGTTCTTTGTT
TTCGACTACACTTCACAAAAGATAATATTACAAATAATACAGCTGCTGCTACAGTGCGACAAGTTGTTACTGTTGTTTTTGAGAGGATGG
TTGCTGAAGATGAACGACACAGAGATATTATAGAACAACCAGTACTGGTACAAGGAAATAGTAACAGAAGATCTGTCAGTACCCTCAAAC
CTTGTGCTAAAGATGCATATATGCTTTTCCAGGATCTTTGTCAGTTGGTTAATGCTGATGCTCCTTATTGGCTAGTGGGCATGACAGAAA
TGACTCGGACGTTTGGCCTCGAATTACTTGAGTCAGTCCTCAATGATTTTCCGCAGGTCTTTTTACAACACCAAGAATTTAGTTTCCTCC
TCAAAGAAAGGGTATGTCCTCTTGTGATAAAGCTCTTTTCTCCAAATATAAAGTTCAGACAAGGTTCCAGCACCTCATCTTCTCCAGCAC
CAGTTGAAAAACCATATTTTCCTATCTGCATGCGTTTGCTGAGAGTAGTATCTGTTCTGATTAAGCAGTTTTACAGTCTTTTGGTAACTG
AATGTGAGATATTTCTGTCACTTCTGGTGAAATTTCTGGATGCAGATAAACCACAGTGGCTACGAGCTGTTGCGGTGGAATCAATACACA
GATTCTGTGTGCAGCCTCAACTATTAAGGTCATTTTGTCAGTCCTATGATATGAAACAGCATTCTACCAAGGTTTTTCGTGATATTGTAA
ATGCACTGGGATCTTTTATACAGTCCTTGTTTCTTGTCCCCCCTACTGGAAATCCTGCAACAAGCAACCAAGCTGGAAACAATAATTTAG
GTGGCTCAGTCTCAGCACCAGCTAACTCAGGAATGGTGGGGATTGGTGGAGGTGTTACTTTGCTACCAGCATTTGAATATAGGGGAACCT
GGATACCTATTCTGACAATCACAGTTCAAGGCAGTGCTAAAGCCACCTAAGAGCTAGGAGAGCTTGAAACAGAATGTCAAACCACCACTG
AAGAAGGTTCTTCACCAACACAGTCGACAGAACAGCAGGATTTACAGTCAACATCAGACCAAATGGATAAGGAAATTGGGGGAACTGTTC
AACCCATACTACGACCCTCTCCAGTGGAAGAGCAGCCATTTTGAAAGAAGAGACAACATGAATGACAATTTTCTCGAGGGTGAGGAGGAA
AATGAGCTGACCTTGAACGAGAAGAATTTCTTCCCAGAATACAACTATGACTGGTGGGAGAAAAAGCCCTTCTCTGAGGATGTGAACTGG
GGGTATGAGAAGAGAAACCTCGCCAGGGTCCCCAAGCTGGACCTGAAAAGGCAATATGACAGGGTGGCCCAACTGGACCAGCTCCTTCAC
TACAGGAAGAAGTCAGCTGAGTTTCCAGACTTCTATGATTCTGAGGAGCCGGTGAGCACCCACCAGGAGGCAGAAAATGAAAAGGACAGG
GCTGACCAGACAGTCCTGACAGAGGACGAGAAAAAAGAACTCGAAAACTTGGCTGCAATGGATTTGGAACTACAGAAGATAGCTGAGAAA
TTCAGCCAAAGGGGCTGACTGTCATTGGAGCGGTGGGCACTGTTAAGAAGCAGCCATCACATGATCTGTTTTTCACCACTTCACTGAAAG
ACACCATTTATCTACCCAAGGGCAGAAAGTAGAACTTACTATTCATTAAATGTTTGACACAATTGGAATTGTCTTTAATTTCTGTCAGAA
TGCTATTGAAAATGTGAATTGCATGACTTGTAGCATATTCTTTTCTGCAAAATAGACATATTAACATGCTTATGACAATGACTGTGCTAC

>54569_54569_6_MON2-CHGB_MON2_chr12_62926331_ENST00000552115_CHGB_chr20_5904344_ENST00000378961_length(amino acids)=480AA_BP=
MFVPLGNWLGPWRIMSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCG
TKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAA
ATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLND
FPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDAD
KPQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPATSNQAGNNNLGGSVSAPANSGMVGIG

--------------------------------------------------------------
>54569_54569_7_MON2-CHGB_MON2_chr12_62926331_ENST00000552738_CHGB_chr20_5904344_ENST00000378961_length(transcript)=2671nt_BP=1879nt
AGTCTTAGGGGCCTGGGGAGCTGGCGCTGAAGCTTCTTGCCAGGTTGGCTGGTGACACCCGGTGTGGCTGGGCCCCGCGGCAGCGGAGGG
ACCTGCCCGCCTTGTGGGTTTCTCGGCCAGAGTCGGCGGAGCCTAGCGGGACGGTGCGACTGCGGGGGGCGCCTCCGAGAAAAGCCAGAG
GTGTTGCGGGGAAGCTGCTGGGGGACGCTCGAGCAGGCTCCGGGTTCGCAGCCCAGGGCCCAAGAAGCGGGCTGCTGAAGGACCAGAGAC
ACCGGGAGGGAGCTGCCTGTGGCCCTAAGGAGCTGACCGTGCCAGAGCTTGTTTGTACCTCTCGGAAATTGGCTGGGACCTTGGAGGATC
ATGTCCGGCACCAGCAGCCCCGAGGCGGTGAAGAAGCTGCTGGAGAATATGCAGAGCGACTTGCGCGCCTTGTCACTGGAGTGCAAGAAG
AAATTCCCACCTGTCAAAGAGGCTGCTGAATCAGGAATAATAAAAGTTAAAACAATTGCTGCACGAAACACTGAAATTTTGGCAGCACTG
AAAGAGAACAGCTCAGAGGTTGTACAGCCTTTTTTAATGGGTTGTGGAACCAAGGAACCGAAGATCACTCAGCTATGTTTGGCTGCTATT
CAGAGACTCATGTCACATGAAGTCGTGTCTGAGACTGCAGCTGGAAATATAATTAACATGCTTTGGCAGCTAATGGAGAATAGTCTTGAA
GAACTTAAGCTACTTCAAACAGTTCTTGTTCTTTTAACAACCAATACAGTAGTTCATGATGAGGCACTTTCTAAGGCAATCGTTCTTTGT
TTTCGACTACACTTCACAAAAGATAATATTACAAATAATACAGCTGCTGCTACAGTGCGACAAGTTGTTACTGTTGTTTTTGAGAGGATG
GTTGCTGAAGATGAACGACACAGAGATATTATAGAACAACCAGTACTGGTACAAGGAAATAGTAACAGAAGATCTGTCAGTACCCTCAAA
CCTTGTGCTAAAGATGCATATATGCTTTTCCAGGATCTTTGTCAGTTGGTTAATGCTGATGCTCCTTATTGGCTAGTGGGCATGACAGAA
ATGACTCGGACGTTTGGCCTCGAATTACTTGAGTCAGTCCTCAATGATTTTCCGCAGGTCTTTTTACAACACCAAGAATTTAGTTTCCTC
CTCAAAGAAAGGGTATGTCCTCTTGTGATAAAGCTCTTTTCTCCAAATATAAAGTTCAGACAAGGTTCCAGCACCTCATCTTCTCCAGCA
CCAGTTGAAAAACCATATTTTCCTATCTGCATGCGTTTGCTGAGAGTAGTATCTGTTCTGATTAAGCAGTTTTACAGTCTTTTGGTAACT
GAATGTGAGATATTTCTGTCACTTCTGGTGAAATTTCTGGATGCAGATAAACCACAGTGGCTACGAGCTGTTGCGGTGGAATCAATACAC
AGATTCTGTGTGCAGCCTCAACTATTAAGGTCATTTTGTCAGTCCTATGATATGAAACAGCATTCTACCAAGGTTTTTCGTGATATTGTA
AATGCACTGGGATCTTTTATACAGTCCTTGTTTCTTGTCCCCCCTACTGGAAATCCTGCAACAAGCAACCAAGCTGGAAACAATAATTTA
GGTGGCTCAGTCTCAGCACCAGCTAACTCAGGAATGGTGGGGATTGGTGGAGGTGTTACTTTGCTACCAGCATTTGAATATAGGGGAACC
TGGATACCTATTCTGACAATCACAGTTCAAGGCAGTGCTAAAGCCACCTAAGAGCTAGGAGAGCTTGAAACAGAATGTCAAACCACCACT
GAAGAAGGTTCTTCACCAACACAGTCGACAGAACAGCAGGATTTACAGTCAACATCAGACCAAATGGATAAGGAAATTGGGGGAACTGTT
CAACCCATACTACGACCCTCTCCAGTGGAAGAGCAGCCATTTTGAAAGAAGAGACAACATGAATGACAATTTTCTCGAGGGTGAGGAGGA
AAATGAGCTGACCTTGAACGAGAAGAATTTCTTCCCAGAATACAACTATGACTGGTGGGAGAAAAAGCCCTTCTCTGAGGATGTGAACTG
GGGGTATGAGAAGAGAAACCTCGCCAGGGTCCCCAAGCTGGACCTGAAAAGGCAATATGACAGGGTGGCCCAACTGGACCAGCTCCTTCA
CTACAGGAAGAAGTCAGCTGAGTTTCCAGACTTCTATGATTCTGAGGAGCCGGTGAGCACCCACCAGGAGGCAGAAAATGAAAAGGACAG
GGCTGACCAGACAGTCCTGACAGAGGACGAGAAAAAAGAACTCGAAAACTTGGCTGCAATGGATTTGGAACTACAGAAGATAGCTGAGAA
ATTCAGCCAAAGGGGCTGACTGTCATTGGAGCGGTGGGCACTGTTAAGAAGCAGCCATCACATGATCTGTTTTTCACCACTTCACTGAAA
GACACCATTTATCTACCCAAGGGCAGAAAGTAGAACTTACTATTCATTAAATGTTTGACACAATTGGAATTGTCTTTAATTTCTGTCAGA
ATGCTATTGAAAATGTGAATTGCATGACTTGTAGCATATTCTTTTCTGCAAAATAGACATATTAACATGCTTATGACAATGACTGTGCTA

>54569_54569_7_MON2-CHGB_MON2_chr12_62926331_ENST00000552738_CHGB_chr20_5904344_ENST00000378961_length(amino acids)=480AA_BP=
MFVPLGNWLGPWRIMSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCG
TKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAA
ATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLND
FPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDAD
KPQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPATSNQAGNNNLGGSVSAPANSGMVGIG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MON2-CHGB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MON2-CHGB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MON2-CHGB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource