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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MON2-RNF219-AS1 (FusionGDB2 ID:54577)

Fusion Gene Summary for MON2-RNF219-AS1

check button Fusion gene summary
Fusion gene informationFusion gene name: MON2-RNF219-AS1
Fusion gene ID: 54577
HgeneTgene
Gene symbol

MON2

RNF219-AS1

Gene ID

23041

100874222

Gene nameMON2 homolog, regulator of endosome-to-Golgi traffickingOBI1 antisense RNA 1
Synonyms-POU4F1-AS1|RNF219-AS1
Cytomap

12q14.1

13q22.3-q31.1

Type of geneprotein-codingncRNA
Descriptionprotein MON2 homologMON2 regulator of endosome-to-Golgi traffickingPOU4F1 antisense RNA 1 (non-protein coding)RNF219 antisense RNA 1
Modification date2020031320200313
UniProtAcc

Q7Z3U7

.
Ensembl transtripts involved in fusion geneENST00000393630, ENST00000393632, 
ENST00000546600, ENST00000280379, 
ENST00000393629, ENST00000549378, 
ENST00000551397, ENST00000552115, 
ENST00000552738, 		ENST00000430549, 
ENST00000444769, ENST00000560209, 
ENST00000560584, ENST00000605996, 
ENST00000606124, ENST00000606187, 
ENST00000606376, ENST00000606429, 
ENST00000606803, ENST00000607205, 
ENST00000607220, ENST00000607860, 
ENST00000607862, 
Fusion gene scores* DoF score18 X 13 X 7=16387 X 7 X 1=49
# samples 197
** MAII scorelog2(19/1638*10)=-3.10786403331006
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/49*10)=0.514573172829758
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: MON2 [Title/Abstract] AND RNF219-AS1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMON2(62987058)-RNF219-AS1(79009891), # samples:14
RNF219-AS1(79009891)-MON2(62987058), # samples:6
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MON2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check buttonFusion gene breakpoints across RNF219-AS1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/AAW020608MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/AAW020714MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/AAW021018MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/AAW021160MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/AAW021184MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/AAW021474MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/AAW022645MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/AAW022762MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/AAW022779MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/AAW023040MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/ABI493888MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/ABI494151MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/ABI496159MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
ChiTaRS5.0N/ABI497084MON2chr12

62987058

+RNF219-AS1chr13

79009891

+


Top

Fusion Gene ORF analysis for MON2-RNF219-AS1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-intronENST00000393630ENST00000430549MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000444769MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000560209MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000560584MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000605996MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000606124MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000606187MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000606376MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000606429MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000606803MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000607205MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000607220MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000607860MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393630ENST00000607862MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000430549MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000444769MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000560209MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000560584MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000605996MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000606124MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000606187MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000606376MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000606429MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000606803MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000607205MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000607220MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000607860MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
3UTR-intronENST00000393632ENST00000607862MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000430549MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000444769MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000560209MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000560584MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000605996MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000606124MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000606187MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000606376MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000606429MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000606803MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000607205MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000607220MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000607860MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
5CDS-intronENST00000546600ENST00000607862MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000430549MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000444769MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000560209MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000560584MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000605996MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000606124MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000606187MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000606376MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000606429MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000606803MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000607205MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000607220MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000607860MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000280379ENST00000607862MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000430549MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000444769MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000560209MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000560584MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000605996MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000606124MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000606187MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000606376MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000606429MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000606803MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000607205MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000607220MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000607860MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000393629ENST00000607862MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000430549MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000444769MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000560209MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000560584MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000605996MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000606124MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000606187MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000606376MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000606429MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000606803MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000607205MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000607220MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000607860MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000549378ENST00000607862MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000430549MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000444769MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000560209MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000560584MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000605996MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000606124MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000606187MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000606376MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000606429MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000606803MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000607205MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000607220MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000607860MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000551397ENST00000607862MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000430549MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000444769MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000560209MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000560584MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000605996MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000606124MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000606187MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000606376MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000606429MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000606803MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000607205MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000607220MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000607860MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552115ENST00000607862MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000430549MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000444769MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000560209MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000560584MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000605996MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000606124MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000606187MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000606376MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000606429MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000606803MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000607205MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000607220MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000607860MON2chr12

62987058

+RNF219-AS1chr13

79009891

+
intron-intronENST00000552738ENST00000607862MON2chr12

62987058

+RNF219-AS1chr13

79009891

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

Top

Fusion Genomic Features for MON2-RNF219-AS1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MON2-RNF219-AS1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:62987058/:79009891)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MON2

Q7Z3U7

.
FUNCTION: Plays a role in regulating membrane trafficking of cargo proteins. Together with ATP9A and DOP1B, regulates SNX3 retromer-mediated endosomal sorting of WLS away from lysosomal degradation. {ECO:0000269|PubMed:30213940}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for MON2-RNF219-AS1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for MON2-RNF219-AS1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MON2-RNF219-AS1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MON2-RNF219-AS1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource