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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MORF4L1-PSMA4 (FusionGDB2 ID:54605)

Fusion Gene Summary for MORF4L1-PSMA4

check button Fusion gene summary
Fusion gene informationFusion gene name: MORF4L1-PSMA4
Fusion gene ID: 54605
HgeneTgene
Gene symbol

MORF4L1

PSMA4

Gene ID

10933

5685

Gene namemortality factor 4 like 1proteasome 20S subunit alpha 4
SynonymsEaf3|FWP006|HsT17725|MEAF3|MORFRG15|MRG15|S863-6HC9|HsT17706|PSC9
Cytomap

15q25.1

15q25.1

Type of geneprotein-codingprotein-coding
Descriptionmortality factor 4-like protein 1Esa1p-associated factor 3 homologMORF-related gene 15 proteinMORF-related gene on chromosome 15protein MSL3-1transcription factor-like protein MRG15proteasome subunit alpha type-4macropain subunit C9multicatalytic endopeptidase complex subunit C9proteasome (prosome, macropain) subunit, alpha type, 4proteasome component C9proteasome subunit HC9proteasome subunit Lproteasome subunit alpha 4prot
Modification date2020031320200327
UniProtAcc

Q9UBU8

.
Ensembl transtripts involved in fusion geneENST00000331268, ENST00000379535, 
ENST00000426013, ENST00000558502, 
ENST00000558746, ENST00000559345, 
ENST00000561171, 		ENST00000557929, 
ENST00000558094, ENST00000558281, 
ENST00000558341, ENST00000044462, 
ENST00000560217, ENST00000413382, 
ENST00000559082, 
Fusion gene scores* DoF score9 X 8 X 4=28811 X 11 X 5=605
# samples 1111
** MAII scorelog2(11/288*10)=-1.38856528791765
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/605*10)=-2.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MORF4L1 [Title/Abstract] AND PSMA4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMORF4L1(79186572)-PSMA4(78841131), # samples:1
Anticipated loss of major functional domain due to fusion event.MORF4L1-PSMA4 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
MORF4L1-PSMA4 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
MORF4L1-PSMA4 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
MORF4L1-PSMA4 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMORF4L1

GO:0000724

double-strand break repair via homologous recombination

20332121

HgeneMORF4L1

GO:0016575

histone deacetylation

14966270

HgeneMORF4L1

GO:0043967

histone H4 acetylation

14966270

HgeneMORF4L1

GO:0043968

histone H2A acetylation

14966270


check buttonFusion gene breakpoints across MORF4L1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PSMA4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-24-1562MORF4L1chr15

79186572

+PSMA4chr15

78841131

+


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Fusion Gene ORF analysis for MORF4L1-PSMA4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000331268ENST00000557929MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000331268ENST00000558094MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000331268ENST00000558281MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000331268ENST00000558341MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000379535ENST00000557929MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000379535ENST00000558094MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000379535ENST00000558281MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000379535ENST00000558341MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000426013ENST00000557929MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000426013ENST00000558094MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000426013ENST00000558281MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000426013ENST00000558341MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000558502ENST00000557929MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000558502ENST00000558094MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000558502ENST00000558281MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000558502ENST00000558341MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000558746ENST00000557929MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000558746ENST00000558094MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000558746ENST00000558281MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000558746ENST00000558341MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000559345ENST00000557929MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000559345ENST00000558094MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000559345ENST00000558281MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
5CDS-intronENST00000559345ENST00000558341MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000331268ENST00000044462MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000331268ENST00000560217MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000379535ENST00000044462MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000379535ENST00000560217MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000426013ENST00000044462MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000426013ENST00000560217MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000558502ENST00000044462MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000558502ENST00000560217MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000558746ENST00000044462MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000558746ENST00000560217MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000559345ENST00000044462MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
Frame-shiftENST00000559345ENST00000560217MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000331268ENST00000413382MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000331268ENST00000559082MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000379535ENST00000413382MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000379535ENST00000559082MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000426013ENST00000413382MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000426013ENST00000559082MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000558502ENST00000413382MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000558502ENST00000559082MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000558746ENST00000413382MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000558746ENST00000559082MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000559345ENST00000413382MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
In-frameENST00000559345ENST00000559082MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
intron-3CDSENST00000561171ENST00000044462MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
intron-3CDSENST00000561171ENST00000413382MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
intron-3CDSENST00000561171ENST00000559082MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
intron-3CDSENST00000561171ENST00000560217MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
intron-intronENST00000561171ENST00000557929MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
intron-intronENST00000561171ENST00000558094MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
intron-intronENST00000561171ENST00000558281MORF4L1chr15

79186572

+PSMA4chr15

78841131

+
intron-intronENST00000561171ENST00000558341MORF4L1chr15

79186572

+PSMA4chr15

78841131

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000379535MORF4L1chr1579186572+ENST00000559082PSMA4chr1578841131+183814414111595394
ENST00000379535MORF4L1chr1579186572+ENST00000413382PSMA4chr1578841131+185614414111595394
ENST00000426013MORF4L1chr1579186572+ENST00000559082PSMA4chr1578841131+144110442421198318
ENST00000426013MORF4L1chr1579186572+ENST00000413382PSMA4chr1578841131+145910442421198318
ENST00000331268MORF4L1chr1579186572+ENST00000559082PSMA4chr1578841131+152011232041277357
ENST00000331268MORF4L1chr1579186572+ENST00000413382PSMA4chr1578841131+153811232041277357
ENST00000558746MORF4L1chr1579186572+ENST00000559082PSMA4chr1578841131+118278564939291
ENST00000558746MORF4L1chr1579186572+ENST00000413382PSMA4chr1578841131+120078564939291
ENST00000559345MORF4L1chr1579186572+ENST00000559082PSMA4chr1578841131+13739762251130301
ENST00000559345MORF4L1chr1579186572+ENST00000413382PSMA4chr1578841131+13919762251130301
ENST00000558502MORF4L1chr1579186572+ENST00000559082PSMA4chr1578841131+107267580829249
ENST00000558502MORF4L1chr1579186572+ENST00000413382PSMA4chr1578841131+109067580829249

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000379535ENST00000559082MORF4L1chr1579186572+PSMA4chr1578841131+0.0023404820.99765956
ENST00000379535ENST00000413382MORF4L1chr1579186572+PSMA4chr1578841131+0.0024033920.99759656
ENST00000426013ENST00000559082MORF4L1chr1579186572+PSMA4chr1578841131+0.0002951690.9997048
ENST00000426013ENST00000413382MORF4L1chr1579186572+PSMA4chr1578841131+0.0002995960.9997004
ENST00000331268ENST00000559082MORF4L1chr1579186572+PSMA4chr1578841131+0.0006356080.99936444
ENST00000331268ENST00000413382MORF4L1chr1579186572+PSMA4chr1578841131+0.0006444550.9993555
ENST00000558746ENST00000559082MORF4L1chr1579186572+PSMA4chr1578841131+0.0012125940.99878746
ENST00000558746ENST00000413382MORF4L1chr1579186572+PSMA4chr1578841131+0.001287770.9987122
ENST00000559345ENST00000559082MORF4L1chr1579186572+PSMA4chr1578841131+0.0011731230.9988269
ENST00000559345ENST00000413382MORF4L1chr1579186572+PSMA4chr1578841131+0.0012200370.99877995
ENST00000558502ENST00000559082MORF4L1chr1579186572+PSMA4chr1578841131+0.0016141590.9983859
ENST00000558502ENST00000413382MORF4L1chr1579186572+PSMA4chr1578841131+0.0017439210.998256

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Fusion Genomic Features for MORF4L1-PSMA4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for MORF4L1-PSMA4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:79186572/chr15:78841131)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MORF4L1

Q9UBU8

.
FUNCTION: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci. {ECO:0000269|PubMed:14966270, ECO:0000269|PubMed:20332121}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000331268+1113135_146306363.0MotifNuclear localization signal
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000426013+1012135_146267324.0MotifNuclear localization signal
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000558502+810135_146179236.0MotifNuclear localization signal
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000559345+1012135_146179236.0MotifNuclear localization signal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000331268+1113191_362306363.0DomainMRG
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000426013+1012191_362267324.0DomainMRG
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000558502+810191_362179236.0DomainMRG
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000559345+1012191_362179236.0DomainMRG


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Fusion Gene Sequence for MORF4L1-PSMA4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>54605_54605_1_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000331268_PSMA4_chr15_78841131_ENST00000413382_length(transcript)=1538nt_BP=1123nt
GCGTGCGCGGCGGGCTGTCGTTGGCTGGAGCAGCGGCTGCGCGGGTCGCGGTGCTGTGAGGTCTGCGGGCGCTGGCAAATCCGGCCCAGG
ATGTAGAGCTGGCAGTGCCTGACGGCGCGTCTGACGCGGAGTTGGGTGGGGTAGAGAGTAGGGGGCGGTAGTCGGGGGTGGTGGGAGAAG
GAGGAGGCGGCGAATCACTTATAAATGGCGCCGAAGCAGGACCCGAAGCCTAAATTCCAGGAGGGTGAGCGAGTGCTGTGCTTTCATGGG
CCTCTTCTTTATGAAGCAAAGTGTGTAAAGGTTGCCATAAAGGACAAACAAGTGAAATACTTCATACATTACAGTGGTTGGAATAAAAAA
AGTGCTGTGAGGCCCAGGCGCTCTGAAAAATCTTTGAAGACACATGAGGATATTGTAGCCCTTTTTCCTGTTCCTGAAGGAGCTCCCTCA
GTACACCACCCCCTCCTGACCTCTAGTTGGGATGAATGGGTTCCGGAGAGCAGAGTACTCAAATACGTGGACACCAATTTGCAGAAACAG
CGAGAACTTCAAAAAGCCAATCAGGAGCAGTATGCAGAGGGGAAGATGAGAGGGGCTGCCCCAGGAAAGAAGACATCTGGTCTGCAACAG
AAAAATGTTGAAGTGAAAACGAAAAAGAACAAACAGAAAACACCTGGAAATGGAGATGGTGGCAGTACCAGTGAGACCCCTCAGCCTCCT
CGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAGGAAACATTCATGAACAGAGTTGAAGTTAAAGTAAAGATTCCTGAAGAG
CTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGGCAAAAACAGCTCTTTTATCTTCCTGCCAAGAAGAATGTGGATTCCATT
CTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACAGATAATAAGGAGTATGCGGTTAATGAAGTTGTGGCAGGGATAAAAGAA
TACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTTGAGAGACCACAGTATGCTGAAATTCTTGCAGATCATCCCGATGCACCC
ATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTTGTGGAAATTGCAACACTAACAAGAGAGAATGGAAAGACAGTAATCAGA
GTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACATGAGGAAGAAGAAGCCAAAGCTGAGCGTGAGAAGAAAGAAAAAGAACAG
AAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTTGGGGCACCATTTCAGTGTAAAAGCAGTCCTACTCTTCCACACTAGGAA
GGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACATTACATACTGAATTGGGTCCTTGTCATTTCTGTCCAATTGAATACTTTA
TTGTAACGATGATGGTTACCCTTCATGGACGTCTTAATCTTCCACACACATCCCCTTTTTTTGGAATAAAATTTGGAAAATGGAAATGAA

>54605_54605_1_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000331268_PSMA4_chr15_78841131_ENST00000413382_length(amino acids)=357AA_BP=301
MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKKSAVRPRRSEKSLKTHEDIVALFPVPEGAPSVHHPLLTS
SWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVD
PTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGT

--------------------------------------------------------------
>54605_54605_2_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000331268_PSMA4_chr15_78841131_ENST00000559082_length(transcript)=1520nt_BP=1123nt
GCGTGCGCGGCGGGCTGTCGTTGGCTGGAGCAGCGGCTGCGCGGGTCGCGGTGCTGTGAGGTCTGCGGGCGCTGGCAAATCCGGCCCAGG
ATGTAGAGCTGGCAGTGCCTGACGGCGCGTCTGACGCGGAGTTGGGTGGGGTAGAGAGTAGGGGGCGGTAGTCGGGGGTGGTGGGAGAAG
GAGGAGGCGGCGAATCACTTATAAATGGCGCCGAAGCAGGACCCGAAGCCTAAATTCCAGGAGGGTGAGCGAGTGCTGTGCTTTCATGGG
CCTCTTCTTTATGAAGCAAAGTGTGTAAAGGTTGCCATAAAGGACAAACAAGTGAAATACTTCATACATTACAGTGGTTGGAATAAAAAA
AGTGCTGTGAGGCCCAGGCGCTCTGAAAAATCTTTGAAGACACATGAGGATATTGTAGCCCTTTTTCCTGTTCCTGAAGGAGCTCCCTCA
GTACACCACCCCCTCCTGACCTCTAGTTGGGATGAATGGGTTCCGGAGAGCAGAGTACTCAAATACGTGGACACCAATTTGCAGAAACAG
CGAGAACTTCAAAAAGCCAATCAGGAGCAGTATGCAGAGGGGAAGATGAGAGGGGCTGCCCCAGGAAAGAAGACATCTGGTCTGCAACAG
AAAAATGTTGAAGTGAAAACGAAAAAGAACAAACAGAAAACACCTGGAAATGGAGATGGTGGCAGTACCAGTGAGACCCCTCAGCCTCCT
CGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAGGAAACATTCATGAACAGAGTTGAAGTTAAAGTAAAGATTCCTGAAGAG
CTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGGCAAAAACAGCTCTTTTATCTTCCTGCCAAGAAGAATGTGGATTCCATT
CTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACAGATAATAAGGAGTATGCGGTTAATGAAGTTGTGGCAGGGATAAAAGAA
TACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTTGAGAGACCACAGTATGCTGAAATTCTTGCAGATCATCCCGATGCACCC
ATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTTGTGGAAATTGCAACACTAACAAGAGAGAATGGAAAGACAGTAATCAGA
GTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACATGAGGAAGAAGAAGCCAAAGCTGAGCGTGAGAAGAAAGAAAAAGAACAG
AAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTTGGGGCACCATTTCAGTGTAAAAGCAGTCCTACTCTTCCACACTAGGAA
GGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACATTACATACTGAATTGGGTCCTTGTCATTTCTGTCCAATTGAATACTTTA

>54605_54605_2_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000331268_PSMA4_chr15_78841131_ENST00000559082_length(amino acids)=357AA_BP=301
MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKKSAVRPRRSEKSLKTHEDIVALFPVPEGAPSVHHPLLTS
SWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVD
PTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGT

--------------------------------------------------------------
>54605_54605_3_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000379535_PSMA4_chr15_78841131_ENST00000413382_length(transcript)=1856nt_BP=1441nt
AACCCATGGCCGGGAAAAGAAGCTCCTGCTCCCCGCTCCACTCCCGGCGTCTTCACACTTGGGGAAGGGAGAGGCAGGAAGTGCAAGGAC
CGCGCAAGACCCGGCCCCCCGAGCCGCCAGGGGCCGCGCCAGCAGCCCAGATGCGGTGGGCGGGAGCTGGGGGGGCGGCGGGGTCCCGCG
AAGACCTGCGACCTGGCGCCCTCGCCGGCTGTGTCCCGGCCAGCCCGCTTTCCAGGCGAGCCTCGCTAAGGAGTGTGAGAAACCAAATCC
TCAGTGGGTAAACCGCGCTCCGTCCAGCCCACTCGGACGAGAGCTCTCCCGGGAGCCAGGCGCGTTGCTGCACCCGAGGTGGGGAAACCG
GAGCCCGAAGAGCGGAAGGGGCTTATTCCAGGCGACAGGCAGTGTCAGTAACTGAATCAGGGGCCGAGGAAGTTTCCCCAGAAGCGCGGC
TTCGCTCCCGGCCCGGCCCGACCCCGACTACTGTCCCCTAATACCCAGGGAGCGGAAGACGCGACCAACTCCAGGCACAGCGGAGCCGGC
GCGGGGTCCACAAAGCAAAAAAGAATGATCCCCTTCCCCCATCCTCAAGTGACTGATGCTCTTGGAAGATACTCCAACTATATCCTGAGT
AGCACTGTGGAGAGCCCCAGTCTGAGAAGCATGAACTTTGAGAAGCAAGGTGAGCGAGTGCTGTGCTTTCATGGGCCTCTTCTTTATGAA
GCAAAGTGTGTAAAGGTTGCCATAAAGGACAAACAAGTGAAATACTTCATACATTACAGTGGTTGGAATAAAAATTGGGATGAATGGGTT
CCGGAGAGCAGAGTACTCAAATACGTGGACACCAATTTGCAGAAACAGCGAGAACTTCAAAAAGCCAATCAGGAGCAGTATGCAGAGGGG
AAGATGAGAGGGGCTGCCCCAGGAAAGAAGACATCTGGTCTGCAACAGAAAAATGTTGAAGTGAAAACGAAAAAGAACAAACAGAAAACA
CCTGGAAATGGAGATGGTGGCAGTACCAGTGAGACCCCTCAGCCTCCTCGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAG
GAAACATTCATGAACAGAGTTGAAGTTAAAGTAAAGATTCCTGAAGAGCTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGG
CAAAAACAGCTCTTTTATCTTCCTGCCAAGAAGAATGTGGATTCCATTCTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACA
GATAATAAGGAGTATGCGGTTAATGAAGTTGTGGCAGGGATAAAAGAATACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTT
GAGAGACCACAGTATGCTGAAATTCTTGCAGATCATCCCGATGCACCCATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTT
GTGGAAATTGCAACACTAACAAGAGAGAATGGAAAGACAGTAATCAGAGTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACAT
GAGGAAGAAGAAGCCAAAGCTGAGCGTGAGAAGAAAGAAAAAGAACAGAAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTT
GGGGCACCATTTCAGTGTAAAAGCAGTCCTACTCTTCCACACTAGGAAGGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACAT
TACATACTGAATTGGGTCCTTGTCATTTCTGTCCAATTGAATACTTTATTGTAACGATGATGGTTACCCTTCATGGACGTCTTAATCTTC

>54605_54605_3_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000379535_PSMA4_chr15_78841131_ENST00000413382_length(amino acids)=394AA_BP=338
MNQGPRKFPQKRGFAPGPARPRLLSPNTQGAEDATNSRHSGAGAGSTKQKRMIPFPHPQVTDALGRYSNYILSSTVESPSLRSMNFEKQG
ERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQK
NVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSIL
EDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVEIATLTRENGKTVIRV

--------------------------------------------------------------
>54605_54605_4_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000379535_PSMA4_chr15_78841131_ENST00000559082_length(transcript)=1838nt_BP=1441nt
AACCCATGGCCGGGAAAAGAAGCTCCTGCTCCCCGCTCCACTCCCGGCGTCTTCACACTTGGGGAAGGGAGAGGCAGGAAGTGCAAGGAC
CGCGCAAGACCCGGCCCCCCGAGCCGCCAGGGGCCGCGCCAGCAGCCCAGATGCGGTGGGCGGGAGCTGGGGGGGCGGCGGGGTCCCGCG
AAGACCTGCGACCTGGCGCCCTCGCCGGCTGTGTCCCGGCCAGCCCGCTTTCCAGGCGAGCCTCGCTAAGGAGTGTGAGAAACCAAATCC
TCAGTGGGTAAACCGCGCTCCGTCCAGCCCACTCGGACGAGAGCTCTCCCGGGAGCCAGGCGCGTTGCTGCACCCGAGGTGGGGAAACCG
GAGCCCGAAGAGCGGAAGGGGCTTATTCCAGGCGACAGGCAGTGTCAGTAACTGAATCAGGGGCCGAGGAAGTTTCCCCAGAAGCGCGGC
TTCGCTCCCGGCCCGGCCCGACCCCGACTACTGTCCCCTAATACCCAGGGAGCGGAAGACGCGACCAACTCCAGGCACAGCGGAGCCGGC
GCGGGGTCCACAAAGCAAAAAAGAATGATCCCCTTCCCCCATCCTCAAGTGACTGATGCTCTTGGAAGATACTCCAACTATATCCTGAGT
AGCACTGTGGAGAGCCCCAGTCTGAGAAGCATGAACTTTGAGAAGCAAGGTGAGCGAGTGCTGTGCTTTCATGGGCCTCTTCTTTATGAA
GCAAAGTGTGTAAAGGTTGCCATAAAGGACAAACAAGTGAAATACTTCATACATTACAGTGGTTGGAATAAAAATTGGGATGAATGGGTT
CCGGAGAGCAGAGTACTCAAATACGTGGACACCAATTTGCAGAAACAGCGAGAACTTCAAAAAGCCAATCAGGAGCAGTATGCAGAGGGG
AAGATGAGAGGGGCTGCCCCAGGAAAGAAGACATCTGGTCTGCAACAGAAAAATGTTGAAGTGAAAACGAAAAAGAACAAACAGAAAACA
CCTGGAAATGGAGATGGTGGCAGTACCAGTGAGACCCCTCAGCCTCCTCGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAG
GAAACATTCATGAACAGAGTTGAAGTTAAAGTAAAGATTCCTGAAGAGCTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGG
CAAAAACAGCTCTTTTATCTTCCTGCCAAGAAGAATGTGGATTCCATTCTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACA
GATAATAAGGAGTATGCGGTTAATGAAGTTGTGGCAGGGATAAAAGAATACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTT
GAGAGACCACAGTATGCTGAAATTCTTGCAGATCATCCCGATGCACCCATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTT
GTGGAAATTGCAACACTAACAAGAGAGAATGGAAAGACAGTAATCAGAGTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACAT
GAGGAAGAAGAAGCCAAAGCTGAGCGTGAGAAGAAAGAAAAAGAACAGAAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTT
GGGGCACCATTTCAGTGTAAAAGCAGTCCTACTCTTCCACACTAGGAAGGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACAT
TACATACTGAATTGGGTCCTTGTCATTTCTGTCCAATTGAATACTTTATTGTAACGATGATGGTTACCCTTCATGGACGTCTTAATCTTC

>54605_54605_4_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000379535_PSMA4_chr15_78841131_ENST00000559082_length(amino acids)=394AA_BP=338
MNQGPRKFPQKRGFAPGPARPRLLSPNTQGAEDATNSRHSGAGAGSTKQKRMIPFPHPQVTDALGRYSNYILSSTVESPSLRSMNFEKQG
ERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQK
NVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSIL
EDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVEIATLTRENGKTVIRV

--------------------------------------------------------------
>54605_54605_5_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000426013_PSMA4_chr15_78841131_ENST00000413382_length(transcript)=1459nt_BP=1044nt
AGTCCCGGCGTGCCCTGGGGCGGCGCGGGCGCAGGGGCGCGTGCGCGGCGGGCTGTCGTTGGCTGGAGCAGCGGCTGCGCGGGTCGCGGT
GCTGTGAGGTCTGCGGGCGCTGGCAAATCCGGCCCAGGATGTAGAGCTGGCAGTGCCTGACGGCGCGTCTGACGCGGAGTTGGGTGGGGT
AGAGAGTAGGGGGCGGTAGTCGGGGGTGGTGGGAGAAGGAGGAGGCGGCGAATCACTTATAAATGGCGCCGAAGCAGGACCCGAAGCCTA
AATTCCAGGAGGGTGAGCGAGTGCTGTGCTTTCATGGGCCTCTTCTTTATGAAGCAAAGTGTGTAAAGGTTGCCATAAAGGACAAACAAG
TGAAATACTTCATACATTACAGTGGTTGGAATAAAAATTGGGATGAATGGGTTCCGGAGAGCAGAGTACTCAAATACGTGGACACCAATT
TGCAGAAACAGCGAGAACTTCAAAAAGCCAATCAGGAGCAGTATGCAGAGGGGAAGATGAGAGGGGCTGCCCCAGGAAAGAAGACATCTG
GTCTGCAACAGAAAAATGTTGAAGTGAAAACGAAAAAGAACAAACAGAAAACACCTGGAAATGGAGATGGTGGCAGTACCAGTGAGACCC
CTCAGCCTCCTCGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAGGAAACATTCATGAACAGAGTTGAAGTTAAAGTAAAGA
TTCCTGAAGAGCTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGGCAAAAACAGCTCTTTTATCTTCCTGCCAAGAAGAATG
TGGATTCCATTCTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACAGATAATAAGGAGTATGCGGTTAATGAAGTTGTGGCAG
GGATAAAAGAATACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTTGAGAGACCACAGTATGCTGAAATTCTTGCAGATCATC
CCGATGCACCCATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTTGTGGAAATTGCAACACTAACAAGAGAGAATGGAAAGA
CAGTAATCAGAGTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACATGAGGAAGAAGAAGCCAAAGCTGAGCGTGAGAAGAAAG
AAAAAGAACAGAAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTTGGGGCACCATTTCAGTGTAAAAGCAGTCCTACTCTTC
CACACTAGGAAGGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACATTACATACTGAATTGGGTCCTTGTCATTTCTGTCCAAT
TGAATACTTTATTGTAACGATGATGGTTACCCTTCATGGACGTCTTAATCTTCCACACACATCCCCTTTTTTTGGAATAAAATTTGGAAA

>54605_54605_5_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000426013_PSMA4_chr15_78841131_ENST00000413382_length(amino acids)=318AA_BP=262
MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEGKMR
GAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQ
LFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVEI

--------------------------------------------------------------
>54605_54605_6_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000426013_PSMA4_chr15_78841131_ENST00000559082_length(transcript)=1441nt_BP=1044nt
AGTCCCGGCGTGCCCTGGGGCGGCGCGGGCGCAGGGGCGCGTGCGCGGCGGGCTGTCGTTGGCTGGAGCAGCGGCTGCGCGGGTCGCGGT
GCTGTGAGGTCTGCGGGCGCTGGCAAATCCGGCCCAGGATGTAGAGCTGGCAGTGCCTGACGGCGCGTCTGACGCGGAGTTGGGTGGGGT
AGAGAGTAGGGGGCGGTAGTCGGGGGTGGTGGGAGAAGGAGGAGGCGGCGAATCACTTATAAATGGCGCCGAAGCAGGACCCGAAGCCTA
AATTCCAGGAGGGTGAGCGAGTGCTGTGCTTTCATGGGCCTCTTCTTTATGAAGCAAAGTGTGTAAAGGTTGCCATAAAGGACAAACAAG
TGAAATACTTCATACATTACAGTGGTTGGAATAAAAATTGGGATGAATGGGTTCCGGAGAGCAGAGTACTCAAATACGTGGACACCAATT
TGCAGAAACAGCGAGAACTTCAAAAAGCCAATCAGGAGCAGTATGCAGAGGGGAAGATGAGAGGGGCTGCCCCAGGAAAGAAGACATCTG
GTCTGCAACAGAAAAATGTTGAAGTGAAAACGAAAAAGAACAAACAGAAAACACCTGGAAATGGAGATGGTGGCAGTACCAGTGAGACCC
CTCAGCCTCCTCGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAGGAAACATTCATGAACAGAGTTGAAGTTAAAGTAAAGA
TTCCTGAAGAGCTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGGCAAAAACAGCTCTTTTATCTTCCTGCCAAGAAGAATG
TGGATTCCATTCTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACAGATAATAAGGAGTATGCGGTTAATGAAGTTGTGGCAG
GGATAAAAGAATACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTTGAGAGACCACAGTATGCTGAAATTCTTGCAGATCATC
CCGATGCACCCATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTTGTGGAAATTGCAACACTAACAAGAGAGAATGGAAAGA
CAGTAATCAGAGTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACATGAGGAAGAAGAAGCCAAAGCTGAGCGTGAGAAGAAAG
AAAAAGAACAGAAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTTGGGGCACCATTTCAGTGTAAAAGCAGTCCTACTCTTC
CACACTAGGAAGGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACATTACATACTGAATTGGGTCCTTGTCATTTCTGTCCAAT
TGAATACTTTATTGTAACGATGATGGTTACCCTTCATGGACGTCTTAATCTTCCACACACATCCCCTTTTTTTGGAATAAAATTTGGAAA

>54605_54605_6_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000426013_PSMA4_chr15_78841131_ENST00000559082_length(amino acids)=318AA_BP=262
MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEGKMR
GAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQ
LFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVEI

--------------------------------------------------------------
>54605_54605_7_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000558502_PSMA4_chr15_78841131_ENST00000413382_length(transcript)=1090nt_BP=675nt
CAGGACCCGAAGCCTAAATTCCAGGAGGTTGGGATGAATGGGTTCCGGAGAGCAGAGTACTCAAATACGTGGACACCAATTTGCAGAAAC
AGCGAGAACTTCAAAAAGCCAATCAGGAGCAGTATGCAGAGGGGAAGATGAGAGGGGCTGCCCCAGGAAAGAAGACATCTGGTCTGCAAC
AGAAAAATGTTGAAGTGAAAACGAAAAAGAACAAACAGAAAACACCTGGAAATGGAGATGGTGGCAGTACCAGTGAGACCCCTCAGCCTC
CTCGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAGGAAACATTCATGAACAGAGTTGAAGTTAAAGTAAAGATTCCTGAAG
AGCTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGGCAAAAACAGCTCTTTTATCTTCCTGCCAAGAAGAATGTGGATTCCA
TTCTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACAGATAATAAGGAGTATGCGGTTAATGAAGTTGTGGCAGGGATAAAAG
AATACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTTGAGAGACCACAGTATGCTGAAATTCTTGCAGATCATCCCGATGCAC
CCATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTTGTGGAAATTGCAACACTAACAAGAGAGAATGGAAAGACAGTAATCA
GAGTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACATGAGGAAGAAGAAGCCAAAGCTGAGCGTGAGAAGAAAGAAAAAGAAC
AGAAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTTGGGGCACCATTTCAGTGTAAAAGCAGTCCTACTCTTCCACACTAGG
AAGGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACATTACATACTGAATTGGGTCCTTGTCATTTCTGTCCAATTGAATACTT
TATTGTAACGATGATGGTTACCCTTCATGGACGTCTTAATCTTCCACACACATCCCCTTTTTTTGGAATAAAATTTGGAAAATGGAAATG

>54605_54605_7_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000558502_PSMA4_chr15_78841131_ENST00000413382_length(amino acids)=249AA_BP=193
MQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVK
IPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADH

--------------------------------------------------------------
>54605_54605_8_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000558502_PSMA4_chr15_78841131_ENST00000559082_length(transcript)=1072nt_BP=675nt
CAGGACCCGAAGCCTAAATTCCAGGAGGTTGGGATGAATGGGTTCCGGAGAGCAGAGTACTCAAATACGTGGACACCAATTTGCAGAAAC
AGCGAGAACTTCAAAAAGCCAATCAGGAGCAGTATGCAGAGGGGAAGATGAGAGGGGCTGCCCCAGGAAAGAAGACATCTGGTCTGCAAC
AGAAAAATGTTGAAGTGAAAACGAAAAAGAACAAACAGAAAACACCTGGAAATGGAGATGGTGGCAGTACCAGTGAGACCCCTCAGCCTC
CTCGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAGGAAACATTCATGAACAGAGTTGAAGTTAAAGTAAAGATTCCTGAAG
AGCTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGGCAAAAACAGCTCTTTTATCTTCCTGCCAAGAAGAATGTGGATTCCA
TTCTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACAGATAATAAGGAGTATGCGGTTAATGAAGTTGTGGCAGGGATAAAAG
AATACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTTGAGAGACCACAGTATGCTGAAATTCTTGCAGATCATCCCGATGCAC
CCATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTTGTGGAAATTGCAACACTAACAAGAGAGAATGGAAAGACAGTAATCA
GAGTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACATGAGGAAGAAGAAGCCAAAGCTGAGCGTGAGAAGAAAGAAAAAGAAC
AGAAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTTGGGGCACCATTTCAGTGTAAAAGCAGTCCTACTCTTCCACACTAGG
AAGGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACATTACATACTGAATTGGGTCCTTGTCATTTCTGTCCAATTGAATACTT

>54605_54605_8_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000558502_PSMA4_chr15_78841131_ENST00000559082_length(amino acids)=249AA_BP=193
MQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVK
IPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADH

--------------------------------------------------------------
>54605_54605_9_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000558746_PSMA4_chr15_78841131_ENST00000413382_length(transcript)=1200nt_BP=785nt
GTAGAGAGTAGGGGGCGGTAGTCGGGGGTGGTGGGAGAAGGAGGAGGCGGCGAATCACTTATAAATGGCGCCGAAGCAGGACCCGAAGCC
TAAATTCCAGGAGGGTGAGCGAGTGCTGTGCTTTCATGGGCCTCTTCTTTATGAAGCAAAGTGTGTAAAGGTTGCCATAAAGGACAAACA
AGTGAAATACTTCATACATTACAGTGGTTGGAATAAAAATTGGGATGAATGGGTTCCGGAGAGCAGAGTACTCAAATACGTGGACACCAA
TTTGCAGAAACAGCGAGAACTTCAAAAAGCCAATCAGAAAACGAAAAAGAACAAACAGAAAACACCTGGAAATGGAGATGGTGGCAGTAC
CAGTGAGACCCCTCAGCCTCCTCGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAGGAAACATTCATGAACAGAGTTGAAGT
TAAAGTAAAGATTCCTGAAGAGCTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGGCAAAAACAGCTCTTTTATCTTCCTGC
CAAGAAGAATGTGGATTCCATTCTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACAGATAATAAGGAGTATGCGGTTAATGA
AGTTGTGGCAGGGATAAAAGAATACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTTGAGAGACCACAGTATGCTGAAATTCT
TGCAGATCATCCCGATGCACCCATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTTGTGGAAATTGCAACACTAACAAGAGA
GAATGGAAAGACAGTAATCAGAGTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACATGAGGAAGAAGAAGCCAAAGCTGAGCG
TGAGAAGAAAGAAAAAGAACAGAAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTTGGGGCACCATTTCAGTGTAAAAGCAG
TCCTACTCTTCCACACTAGGAAGGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACATTACATACTGAATTGGGTCCTTGTCAT
TTCTGTCCAATTGAATACTTTATTGTAACGATGATGGTTACCCTTCATGGACGTCTTAATCTTCCACACACATCCCCTTTTTTTGGAATA

>54605_54605_9_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000558746_PSMA4_chr15_78841131_ENST00000413382_length(amino acids)=291AA_BP=235
MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQRELQKANQKTKKNKQKT
PGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNT
DNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVEIATLTRENGKTVIRVLKQKEVEQLIKKH

--------------------------------------------------------------
>54605_54605_10_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000558746_PSMA4_chr15_78841131_ENST00000559082_length(transcript)=1182nt_BP=785nt
GTAGAGAGTAGGGGGCGGTAGTCGGGGGTGGTGGGAGAAGGAGGAGGCGGCGAATCACTTATAAATGGCGCCGAAGCAGGACCCGAAGCC
TAAATTCCAGGAGGGTGAGCGAGTGCTGTGCTTTCATGGGCCTCTTCTTTATGAAGCAAAGTGTGTAAAGGTTGCCATAAAGGACAAACA
AGTGAAATACTTCATACATTACAGTGGTTGGAATAAAAATTGGGATGAATGGGTTCCGGAGAGCAGAGTACTCAAATACGTGGACACCAA
TTTGCAGAAACAGCGAGAACTTCAAAAAGCCAATCAGAAAACGAAAAAGAACAAACAGAAAACACCTGGAAATGGAGATGGTGGCAGTAC
CAGTGAGACCCCTCAGCCTCCTCGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAGGAAACATTCATGAACAGAGTTGAAGT
TAAAGTAAAGATTCCTGAAGAGCTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGGCAAAAACAGCTCTTTTATCTTCCTGC
CAAGAAGAATGTGGATTCCATTCTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACAGATAATAAGGAGTATGCGGTTAATGA
AGTTGTGGCAGGGATAAAAGAATACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTTGAGAGACCACAGTATGCTGAAATTCT
TGCAGATCATCCCGATGCACCCATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTTGTGGAAATTGCAACACTAACAAGAGA
GAATGGAAAGACAGTAATCAGAGTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACATGAGGAAGAAGAAGCCAAAGCTGAGCG
TGAGAAGAAAGAAAAAGAACAGAAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTTGGGGCACCATTTCAGTGTAAAAGCAG
TCCTACTCTTCCACACTAGGAAGGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACATTACATACTGAATTGGGTCCTTGTCAT
TTCTGTCCAATTGAATACTTTATTGTAACGATGATGGTTACCCTTCATGGACGTCTTAATCTTCCACACACATCCCCTTTTTTTGGAATA

>54605_54605_10_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000558746_PSMA4_chr15_78841131_ENST00000559082_length(amino acids)=291AA_BP=235
MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQRELQKANQKTKKNKQKT
PGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNT
DNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVEIATLTRENGKTVIRVLKQKEVEQLIKKH

--------------------------------------------------------------
>54605_54605_11_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000559345_PSMA4_chr15_78841131_ENST00000413382_length(transcript)=1391nt_BP=976nt
GAATCACTTATAAATGGCGCCGAAGCAGGACCCGAAGCCTAAATTCCAGGAGGGTGAGTGTGCGCCTTTGGGAAAAAGGCACCTAACGGC
GCAGGAGATAGAGGCGGGCTCGAGGTGATTGAGGCTTGAGGGCCGGGGGCGGCGCGGGCTGCGCCCTGAGAAGGCGGCGGTCAGTGCTTT
GTGCGGGGAAAGCGCATTGCGGATGGCAATTCCGGTGAGCGAGTGCTGTGCTTTCATGGGCCTCTTCTTTATGAAGCAAAGTGTGTAAAG
GTTGCCATAAAGGACAAACAAGTGAAATACTTCATACATTACAGTGGTTGGAATAAAAATTGGGATGAATGGGTTCCGGAGAGCAGAGTA
CTCAAATACGTGGACACCAATTTGCAGAAACAGCGAGAACTTCAAAAAGCCAATCAGGAGCAGTATGCAGAGGGGAAGATGAGAGGGGCT
GCCCCAGGAAAGAAGACATCTGGTCTGCAACAGAAAAATGTTGAAGTGAAAACGAAAAAGAACAAACAGAAAACACCTGGAAATGGAGAT
GGTGGCAGTACCAGTGAGACCCCTCAGCCTCCTCGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAGGAAACATTCATGAAC
AGAGTTGAAGTTAAAGTAAAGATTCCTGAAGAGCTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGGCAAAAACAGCTCTTT
TATCTTCCTGCCAAGAAGAATGTGGATTCCATTCTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACAGATAATAAGGAGTAT
GCGGTTAATGAAGTTGTGGCAGGGATAAAAGAATACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTTGAGAGACCACAGTAT
GCTGAAATTCTTGCAGATCATCCCGATGCACCCATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTTGTGGAAATTGCAACA
CTAACAAGAGAGAATGGAAAGACAGTAATCAGAGTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACATGAGGAAGAAGAAGCC
AAAGCTGAGCGTGAGAAGAAAGAAAAAGAACAGAAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTTGGGGCACCATTTCAG
TGTAAAAGCAGTCCTACTCTTCCACACTAGGAAGGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACATTACATACTGAATTGG
GTCCTTGTCATTTCTGTCCAATTGAATACTTTATTGTAACGATGATGGTTACCCTTCATGGACGTCTTAATCTTCCACACACATCCCCTT

>54605_54605_11_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000559345_PSMA4_chr15_78841131_ENST00000413382_length(amino acids)=301AA_BP=245
MCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVE
VKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDY
ANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVEIATLTRENGKTVIRVLKQ

--------------------------------------------------------------
>54605_54605_12_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000559345_PSMA4_chr15_78841131_ENST00000559082_length(transcript)=1373nt_BP=976nt
GAATCACTTATAAATGGCGCCGAAGCAGGACCCGAAGCCTAAATTCCAGGAGGGTGAGTGTGCGCCTTTGGGAAAAAGGCACCTAACGGC
GCAGGAGATAGAGGCGGGCTCGAGGTGATTGAGGCTTGAGGGCCGGGGGCGGCGCGGGCTGCGCCCTGAGAAGGCGGCGGTCAGTGCTTT
GTGCGGGGAAAGCGCATTGCGGATGGCAATTCCGGTGAGCGAGTGCTGTGCTTTCATGGGCCTCTTCTTTATGAAGCAAAGTGTGTAAAG
GTTGCCATAAAGGACAAACAAGTGAAATACTTCATACATTACAGTGGTTGGAATAAAAATTGGGATGAATGGGTTCCGGAGAGCAGAGTA
CTCAAATACGTGGACACCAATTTGCAGAAACAGCGAGAACTTCAAAAAGCCAATCAGGAGCAGTATGCAGAGGGGAAGATGAGAGGGGCT
GCCCCAGGAAAGAAGACATCTGGTCTGCAACAGAAAAATGTTGAAGTGAAAACGAAAAAGAACAAACAGAAAACACCTGGAAATGGAGAT
GGTGGCAGTACCAGTGAGACCCCTCAGCCTCCTCGGAAGAAAAGGGCCCGGGTAGATCCTACTGTTGAAAATGAGGAAACATTCATGAAC
AGAGTTGAAGTTAAAGTAAAGATTCCTGAAGAGCTAAAACCGTGGCTTGTTGATGACTGGGACTTAATTACCAGGCAAAAACAGCTCTTT
TATCTTCCTGCCAAGAAGAATGTGGATTCCATTCTTGAGGATTATGCAAATTACAAGAAATCTCGTGGAAACACAGATAATAAGGAGTAT
GCGGTTAATGAAGTTGTGGCAGGGATAAAAGAATACTTCAACGTAATGTTGGGTACCCAGCTACTCTATAAATTTGAGAGACCACAGTAT
GCTGAAATTCTTGCAGATCATCCCGATGCACCCATGTCCCAGGTGTATGGAGCGCCACATCTCCTGAGATTATTTGTGGAAATTGCAACA
CTAACAAGAGAGAATGGAAAGACAGTAATCAGAGTTCTCAAACAAAAAGAAGTGGAGCAGTTGATCAAAAAACATGAGGAAGAAGAAGCC
AAAGCTGAGCGTGAGAAGAAAGAAAAAGAACAGAAAGAAAAGGATAAATAGAATCAGAGATTTTATTACTCATTTGGGGCACCATTTCAG
TGTAAAAGCAGTCCTACTCTTCCACACTAGGAAGGCTTTACTTTTTTTAACTGGTGCAGTGGGAAAATAGGACATTACATACTGAATTGG
GTCCTTGTCATTTCTGTCCAATTGAATACTTTATTGTAACGATGATGGTTACCCTTCATGGACGTCTTAATCTTCCACACACATCCCCTT

>54605_54605_12_MORF4L1-PSMA4_MORF4L1_chr15_79186572_ENST00000559345_PSMA4_chr15_78841131_ENST00000559082_length(amino acids)=301AA_BP=245
MCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKNWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVE
VKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDY
ANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVEIATLTRENGKTVIRVLKQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MORF4L1-PSMA4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000331268+111326_62306.3333333333333363.0KAT8
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000426013+101226_62267.3333333333333324.0KAT8
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000558502+81026_62179.33333333333334236.0KAT8
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000559345+101226_62179.33333333333334236.0KAT8
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000331268+1113164_230306.3333333333333363.0RB1-1
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000426013+1012164_230267.3333333333333324.0RB1-1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000558502+810164_230179.33333333333334236.0RB1-1
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000559345+1012164_230179.33333333333334236.0RB1-1
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000331268+1113323_344306.3333333333333363.0RB1-2
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000426013+1012323_344267.3333333333333324.0RB1-2
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000558502+810323_344179.33333333333334236.0RB1-2
HgeneMORF4L1chr15:79186572chr15:78841131ENST00000559345+1012323_344179.33333333333334236.0RB1-2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MORF4L1-PSMA4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MORF4L1-PSMA4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource