FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:MPI-ESYT1 (FusionGDB2 ID:54715)

Fusion Gene Summary for MPI-ESYT1

check button Fusion gene summary
Fusion gene informationFusion gene name: MPI-ESYT1
Fusion gene ID: 54715
HgeneTgene
Gene symbol

MPI

ESYT1

Gene ID

6590

23344

Gene namesecretory leukocyte peptidase inhibitorextended synaptotagmin 1
SynonymsALK1|ALP|BLPI|HUSI|HUSI-I|MPI|WAP4|WFDC4FAM62A|MBC2
Cytomap

20q13.12

12q13.2

Type of geneprotein-codingprotein-coding
DescriptionantileukoproteinaseHUSI-1WAP four-disulfide core domain protein 4mucus proteinase inhibitorprotease inhibitor WAP4secretory leukocyte protease inhibitor (antileukoproteinase)seminal proteinase inhibitorextended synaptotagmin-1extended synaptotagmin like protein 1extended synaptotagmin protein 1family with sequence similarity 62 (C2 domain containing), member Amembrane-bound C2 domain-containing protein
Modification date2020031320200313
UniProtAcc

P34949

Q9BSJ8

Ensembl transtripts involved in fusion geneENST00000323744, ENST00000352410, 
ENST00000535694, ENST00000562606, 
ENST00000563422, ENST00000563786, 
ENST00000564003, ENST00000565576, 
ENST00000566377, 		ENST00000550878, 
ENST00000267113, ENST00000394048, 
ENST00000541590, 
Fusion gene scores* DoF score2 X 1 X 2=46 X 6 X 3=108
# samples 26
** MAII scorelog2(2/4*10)=2.32192809488736log2(6/108*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MPI [Title/Abstract] AND ESYT1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMPI(75185143)-ESYT1(56537606), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneMPI

GO:0019731

antibacterial humoral response

18714013

HgeneMPI

GO:0032091

negative regulation of protein binding

19333378

HgeneMPI

GO:0035821

modification of morphology or physiology of other organism

2467900

HgeneMPI

GO:0045071

negative regulation of viral genome replication

19333378


check buttonFusion gene breakpoints across MPI (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ESYT1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-23-1023MPIchr15

75185143

+ESYT1chr12

56537606

+


Top

Fusion Gene ORF analysis for MPI-ESYT1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000323744ENST00000550878MPIchr15

75185143

+ESYT1chr12

56537606

+
5CDS-intronENST00000352410ENST00000550878MPIchr15

75185143

+ESYT1chr12

56537606

+
5CDS-intronENST00000535694ENST00000550878MPIchr15

75185143

+ESYT1chr12

56537606

+
5CDS-intronENST00000562606ENST00000550878MPIchr15

75185143

+ESYT1chr12

56537606

+
5CDS-intronENST00000563422ENST00000550878MPIchr15

75185143

+ESYT1chr12

56537606

+
5CDS-intronENST00000563786ENST00000550878MPIchr15

75185143

+ESYT1chr12

56537606

+
5CDS-intronENST00000564003ENST00000550878MPIchr15

75185143

+ESYT1chr12

56537606

+
5CDS-intronENST00000565576ENST00000550878MPIchr15

75185143

+ESYT1chr12

56537606

+
5CDS-intronENST00000566377ENST00000550878MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000323744ENST00000267113MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000323744ENST00000394048MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000323744ENST00000541590MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000352410ENST00000267113MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000352410ENST00000394048MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000352410ENST00000541590MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000535694ENST00000267113MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000535694ENST00000394048MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000535694ENST00000541590MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000562606ENST00000267113MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000562606ENST00000394048MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000562606ENST00000541590MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000563422ENST00000267113MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000563422ENST00000394048MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000563422ENST00000541590MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000563786ENST00000267113MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000563786ENST00000394048MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000563786ENST00000541590MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000564003ENST00000267113MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000564003ENST00000394048MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000564003ENST00000541590MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000565576ENST00000267113MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000565576ENST00000394048MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000565576ENST00000541590MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000566377ENST00000267113MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000566377ENST00000394048MPIchr15

75185143

+ESYT1chr12

56537606

+
In-frameENST00000566377ENST00000541590MPIchr15

75185143

+ESYT1chr12

56537606

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000352410MPIchr1575185143+ENST00000394048ESYT1chr1256537606+140355449564171
ENST00000352410MPIchr1575185143+ENST00000267113ESYT1chr1256537606+77355449564171
ENST00000352410MPIchr1575185143+ENST00000541590ESYT1chr1256537606+92355449564171
ENST00000566377MPIchr1575185143+ENST00000394048ESYT1chr1256537606+137152217532171
ENST00000566377MPIchr1575185143+ENST00000267113ESYT1chr1256537606+74152217532171
ENST00000566377MPIchr1575185143+ENST00000541590ESYT1chr1256537606+89152217532171
ENST00000563422MPIchr1575185143+ENST00000394048ESYT1chr1256537606+136851914529171
ENST00000563422MPIchr1575185143+ENST00000267113ESYT1chr1256537606+73851914529171
ENST00000563422MPIchr1575185143+ENST00000541590ESYT1chr1256537606+88851914529171
ENST00000564003MPIchr1575185143+ENST00000394048ESYT1chr1256537606+124039148401117
ENST00000564003MPIchr1575185143+ENST00000267113ESYT1chr1256537606+61039148401117
ENST00000564003MPIchr1575185143+ENST00000541590ESYT1chr1256537606+76039148401117
ENST00000563786MPIchr1575185143+ENST00000394048ESYT1chr1256537606+1457608115618167
ENST00000563786MPIchr1575185143+ENST00000267113ESYT1chr1256537606+827608115618167
ENST00000563786MPIchr1575185143+ENST00000541590ESYT1chr1256537606+977608115618167
ENST00000535694MPIchr1575185143+ENST00000394048ESYT1chr1256537606+124039148401117
ENST00000535694MPIchr1575185143+ENST00000267113ESYT1chr1256537606+61039148401117
ENST00000535694MPIchr1575185143+ENST00000541590ESYT1chr1256537606+76039148401117
ENST00000323744MPIchr1575185143+ENST00000394048ESYT1chr1256537606+136851914529171
ENST00000323744MPIchr1575185143+ENST00000267113ESYT1chr1256537606+73851914529171
ENST00000323744MPIchr1575185143+ENST00000541590ESYT1chr1256537606+88851914529171
ENST00000562606MPIchr1575185143+ENST00000394048ESYT1chr1256537606+133148255492145
ENST00000562606MPIchr1575185143+ENST00000267113ESYT1chr1256537606+70148255492145
ENST00000562606MPIchr1575185143+ENST00000541590ESYT1chr1256537606+85148255492145
ENST00000565576MPIchr1575185143+ENST00000394048ESYT1chr1256537606+134849912509165
ENST00000565576MPIchr1575185143+ENST00000267113ESYT1chr1256537606+71849912509165
ENST00000565576MPIchr1575185143+ENST00000541590ESYT1chr1256537606+86849912509165

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000352410ENST00000394048MPIchr1575185143+ESYT1chr1256537606+0.0075613690.9924386
ENST00000352410ENST00000267113MPIchr1575185143+ESYT1chr1256537606+0.0076267260.9923733
ENST00000352410ENST00000541590MPIchr1575185143+ESYT1chr1256537606+0.0086379240.99136204
ENST00000566377ENST00000394048MPIchr1575185143+ESYT1chr1256537606+0.008866690.9911333
ENST00000566377ENST00000267113MPIchr1575185143+ESYT1chr1256537606+0.0086839460.9913161
ENST00000566377ENST00000541590MPIchr1575185143+ESYT1chr1256537606+0.0099188760.99008113
ENST00000563422ENST00000394048MPIchr1575185143+ESYT1chr1256537606+0.010368480.9896316
ENST00000563422ENST00000267113MPIchr1575185143+ESYT1chr1256537606+0.0079350020.992065
ENST00000563422ENST00000541590MPIchr1575185143+ESYT1chr1256537606+0.0085565260.99144346
ENST00000564003ENST00000394048MPIchr1575185143+ESYT1chr1256537606+0.031482930.96851707
ENST00000564003ENST00000267113MPIchr1575185143+ESYT1chr1256537606+0.0308115110.96918845
ENST00000564003ENST00000541590MPIchr1575185143+ESYT1chr1256537606+0.053024760.9469753
ENST00000563786ENST00000394048MPIchr1575185143+ESYT1chr1256537606+0.0211764910.97882354
ENST00000563786ENST00000267113MPIchr1575185143+ESYT1chr1256537606+0.020949960.97905
ENST00000563786ENST00000541590MPIchr1575185143+ESYT1chr1256537606+0.0276467760.9723532
ENST00000535694ENST00000394048MPIchr1575185143+ESYT1chr1256537606+0.031482930.96851707
ENST00000535694ENST00000267113MPIchr1575185143+ESYT1chr1256537606+0.0308115110.96918845
ENST00000535694ENST00000541590MPIchr1575185143+ESYT1chr1256537606+0.053024760.9469753
ENST00000323744ENST00000394048MPIchr1575185143+ESYT1chr1256537606+0.010368480.9896316
ENST00000323744ENST00000267113MPIchr1575185143+ESYT1chr1256537606+0.0079350020.992065
ENST00000323744ENST00000541590MPIchr1575185143+ESYT1chr1256537606+0.0085565260.99144346
ENST00000562606ENST00000394048MPIchr1575185143+ESYT1chr1256537606+0.0132556010.9867444
ENST00000562606ENST00000267113MPIchr1575185143+ESYT1chr1256537606+0.0104858450.9895141
ENST00000562606ENST00000541590MPIchr1575185143+ESYT1chr1256537606+0.0151050470.98489493
ENST00000565576ENST00000394048MPIchr1575185143+ESYT1chr1256537606+0.0096762920.99032366
ENST00000565576ENST00000267113MPIchr1575185143+ESYT1chr1256537606+0.0087513250.9912486
ENST00000565576ENST00000541590MPIchr1575185143+ESYT1chr1256537606+0.0108305080.9891695

Top

Fusion Genomic Features for MPI-ESYT1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for MPI-ESYT1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:75185143/chr12:56537606)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MPI

P34949

ESYT1

Q9BSJ8

FUNCTION: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.FUNCTION: Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. {ECO:0000250, ECO:0000269|PubMed:23791178, ECO:0000269|PubMed:24183667}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneESYT1chr15:75185143chr12:56537606ENST00000267113293191_11611011115.0Coiled coilOntology_term=ECO:0000255
TgeneESYT1chr15:75185143chr12:56537606ENST00000394048293191_11610911105.0Coiled coilOntology_term=ECO:0000255
TgeneESYT1chr15:75185143chr12:56537606ENST00000541590293291_1161101975.3333333333334Coiled coilOntology_term=ECO:0000255
TgeneESYT1chr15:75185143chr12:56537606ENST0000026711329311012_101511011115.0Compositional biasNote=Poly-Leu
TgeneESYT1chr15:75185143chr12:56537606ENST000002671132931924_93511011115.0Compositional biasNote=Poly-Ser
TgeneESYT1chr15:75185143chr12:56537606ENST0000039404829311012_101510911105.0Compositional biasNote=Poly-Leu
TgeneESYT1chr15:75185143chr12:56537606ENST000003940482931924_93510911105.0Compositional biasNote=Poly-Ser
TgeneESYT1chr15:75185143chr12:56537606ENST0000054159029321012_10151101975.3333333333334Compositional biasNote=Poly-Leu
TgeneESYT1chr15:75185143chr12:56537606ENST000005415902932924_9351101975.3333333333334Compositional biasNote=Poly-Ser
TgeneESYT1chr15:75185143chr12:56537606ENST000002671132931135_31311011115.0DomainSMP-LTD
TgeneESYT1chr15:75185143chr12:56537606ENST000002671132931312_43311011115.0DomainC2 1
TgeneESYT1chr15:75185143chr12:56537606ENST000002671132931460_58011011115.0DomainC2 2
TgeneESYT1chr15:75185143chr12:56537606ENST000002671132931627_75111011115.0DomainC2 3
TgeneESYT1chr15:75185143chr12:56537606ENST000002671132931777_89911011115.0DomainC2 4
TgeneESYT1chr15:75185143chr12:56537606ENST000002671132931971_109311011115.0DomainC2 5
TgeneESYT1chr15:75185143chr12:56537606ENST000003940482931135_31310911105.0DomainSMP-LTD
TgeneESYT1chr15:75185143chr12:56537606ENST000003940482931312_43310911105.0DomainC2 1
TgeneESYT1chr15:75185143chr12:56537606ENST000003940482931460_58010911105.0DomainC2 2
TgeneESYT1chr15:75185143chr12:56537606ENST000003940482931627_75110911105.0DomainC2 3
TgeneESYT1chr15:75185143chr12:56537606ENST000003940482931777_89910911105.0DomainC2 4
TgeneESYT1chr15:75185143chr12:56537606ENST000003940482931971_109310911105.0DomainC2 5
TgeneESYT1chr15:75185143chr12:56537606ENST000005415902932135_3131101975.3333333333334DomainSMP-LTD
TgeneESYT1chr15:75185143chr12:56537606ENST000005415902932312_4331101975.3333333333334DomainC2 1
TgeneESYT1chr15:75185143chr12:56537606ENST000005415902932460_5801101975.3333333333334DomainC2 2
TgeneESYT1chr15:75185143chr12:56537606ENST000005415902932627_7511101975.3333333333334DomainC2 3
TgeneESYT1chr15:75185143chr12:56537606ENST000005415902932777_8991101975.3333333333334DomainC2 4
TgeneESYT1chr15:75185143chr12:56537606ENST000005415902932971_10931101975.3333333333334DomainC2 5
TgeneESYT1chr15:75185143chr12:56537606ENST0000026711329311018_102511011115.0RegionRequired for phosphatidylinositol 4%2C5-bisphosphate-dependent location at the cell membrane
TgeneESYT1chr15:75185143chr12:56537606ENST0000039404829311018_102510911105.0RegionRequired for phosphatidylinositol 4%2C5-bisphosphate-dependent location at the cell membrane
TgeneESYT1chr15:75185143chr12:56537606ENST0000054159029321018_10251101975.3333333333334RegionRequired for phosphatidylinositol 4%2C5-bisphosphate-dependent location at the cell membrane
TgeneESYT1chr15:75185143chr12:56537606ENST0000026711329311_3811011115.0Topological domainCytoplasmic
TgeneESYT1chr15:75185143chr12:56537606ENST00000267113293160_6211011115.0Topological domainLumenal
TgeneESYT1chr15:75185143chr12:56537606ENST00000267113293184_110411011115.0Topological domainCytoplasmic
TgeneESYT1chr15:75185143chr12:56537606ENST0000039404829311_3810911105.0Topological domainCytoplasmic
TgeneESYT1chr15:75185143chr12:56537606ENST00000394048293160_6210911105.0Topological domainLumenal
TgeneESYT1chr15:75185143chr12:56537606ENST00000394048293184_110410911105.0Topological domainCytoplasmic
TgeneESYT1chr15:75185143chr12:56537606ENST0000054159029321_381101975.3333333333334Topological domainCytoplasmic
TgeneESYT1chr15:75185143chr12:56537606ENST00000541590293260_621101975.3333333333334Topological domainLumenal
TgeneESYT1chr15:75185143chr12:56537606ENST00000541590293284_11041101975.3333333333334Topological domainCytoplasmic
TgeneESYT1chr15:75185143chr12:56537606ENST00000267113293139_5911011115.0TransmembraneHelical
TgeneESYT1chr15:75185143chr12:56537606ENST00000267113293163_8311011115.0TransmembraneHelical
TgeneESYT1chr15:75185143chr12:56537606ENST00000394048293139_5910911105.0TransmembraneHelical
TgeneESYT1chr15:75185143chr12:56537606ENST00000394048293163_8310911105.0TransmembraneHelical
TgeneESYT1chr15:75185143chr12:56537606ENST00000541590293239_591101975.3333333333334TransmembraneHelical
TgeneESYT1chr15:75185143chr12:56537606ENST00000541590293263_831101975.3333333333334TransmembraneHelical


Top

Fusion Gene Sequence for MPI-ESYT1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>54715_54715_1_MPI-ESYT1_MPI_chr15_75185143_ENST00000323744_ESYT1_chr12_56537606_ENST00000267113_length(transcript)=738nt_BP=519nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGA
AGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGT
GGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGG
ACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCC
AGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCA
TTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAA
GGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGA
TGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAG

>54715_54715_1_MPI-ESYT1_MPI_chr15_75185143_ENST00000323744_ESYT1_chr12_56537606_ENST00000267113_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------
>54715_54715_2_MPI-ESYT1_MPI_chr15_75185143_ENST00000323744_ESYT1_chr12_56537606_ENST00000394048_length(transcript)=1368nt_BP=519nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGA
AGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGT
GGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGG
ACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCC
AGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCA
TTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAA
GGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGA
TGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAG
AGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCT
GCACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCCTTCTGTATCTGTGCCTGGCCAGTGGCAGCACTAGCAGTGGTATTAGCTTATGC
CAAATACAGCTTTGGAAGGATCTTTTTTTCTTTAACTAGATGGTCACCTTCTTCCCTACCACACATGGGTGGGAAGGTGGACAGGCTAAC
CTCTCCAGCTGTGAGCCTCTTAGACTACTGCATGTAGCAAATGTTCAGCAGCTCAGGCCCCCATGTCCAGTTCTGTCCCCACTGTCCTCA
ACCCTGTCCTGAAAATTCTACTGCTTTGATGGCTGGGGCCAGTCTCTTGTCACTTTGGAAACTGAGGACGCGTGGATTCTACTCAAGCCT
CCAAGTAGTGGCATATCAGTCTTGGAGCTCCTAGCTGGTGATACGGAGAGGGCTTTGGAGGACTTGGGACAGCAGGGCCAATTTTTTTGC
CCAAGTGCCTAGGCTGCTAACTCACTGACTAGAACTTAATCTGGTACTTTACAGTTTTGCACCAACTCTGCCAAGCCACTGGATCTTACA

>54715_54715_2_MPI-ESYT1_MPI_chr15_75185143_ENST00000323744_ESYT1_chr12_56537606_ENST00000394048_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------
>54715_54715_3_MPI-ESYT1_MPI_chr15_75185143_ENST00000323744_ESYT1_chr12_56537606_ENST00000541590_length(transcript)=888nt_BP=519nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGA
AGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGT
GGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGG
ACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCC
AGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCA
TTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAA
GGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGA
TGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAG
AGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCT

>54715_54715_3_MPI-ESYT1_MPI_chr15_75185143_ENST00000323744_ESYT1_chr12_56537606_ENST00000541590_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------
>54715_54715_4_MPI-ESYT1_MPI_chr15_75185143_ENST00000352410_ESYT1_chr12_56537606_ENST00000267113_length(transcript)=773nt_BP=554nt
GGGCGCAGAGGGCCGCGGGGGCTGCCGGGAAAGGCATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCC
ACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGAAGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGC
CCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACA
GAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTT
CAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCA
CTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGT
AACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCC
TGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCT

>54715_54715_4_MPI-ESYT1_MPI_chr15_75185143_ENST00000352410_ESYT1_chr12_56537606_ENST00000267113_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------
>54715_54715_5_MPI-ESYT1_MPI_chr15_75185143_ENST00000352410_ESYT1_chr12_56537606_ENST00000394048_length(transcript)=1403nt_BP=554nt
GGGCGCAGAGGGCCGCGGGGGCTGCCGGGAAAGGCATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCC
ACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGAAGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGC
CCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACA
GAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTT
CAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCA
CTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGT
AACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCC
TGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCT
AACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGAGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGG
GCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTGCACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCCTTCTGTATCTGTGCCTGG
CCAGTGGCAGCACTAGCAGTGGTATTAGCTTATGCCAAATACAGCTTTGGAAGGATCTTTTTTTCTTTAACTAGATGGTCACCTTCTTCC
CTACCACACATGGGTGGGAAGGTGGACAGGCTAACCTCTCCAGCTGTGAGCCTCTTAGACTACTGCATGTAGCAAATGTTCAGCAGCTCA
GGCCCCCATGTCCAGTTCTGTCCCCACTGTCCTCAACCCTGTCCTGAAAATTCTACTGCTTTGATGGCTGGGGCCAGTCTCTTGTCACTT
TGGAAACTGAGGACGCGTGGATTCTACTCAAGCCTCCAAGTAGTGGCATATCAGTCTTGGAGCTCCTAGCTGGTGATACGGAGAGGGCTT
TGGAGGACTTGGGACAGCAGGGCCAATTTTTTTGCCCAAGTGCCTAGGCTGCTAACTCACTGACTAGAACTTAATCTGGTACTTTACAGT

>54715_54715_5_MPI-ESYT1_MPI_chr15_75185143_ENST00000352410_ESYT1_chr12_56537606_ENST00000394048_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------
>54715_54715_6_MPI-ESYT1_MPI_chr15_75185143_ENST00000352410_ESYT1_chr12_56537606_ENST00000541590_length(transcript)=923nt_BP=554nt
GGGCGCAGAGGGCCGCGGGGGCTGCCGGGAAAGGCATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCC
ACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGAAGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGC
CCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACA
GAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTT
CAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCA
CTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGT
AACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCC
TGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCT
AACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGAGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGG
GCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTGCACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCCTTCTGTATCTGTGCCTGG

>54715_54715_6_MPI-ESYT1_MPI_chr15_75185143_ENST00000352410_ESYT1_chr12_56537606_ENST00000541590_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------
>54715_54715_7_MPI-ESYT1_MPI_chr15_75185143_ENST00000535694_ESYT1_chr12_56537606_ENST00000267113_length(transcript)=610nt_BP=391nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTT
GACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGC
AACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCAC
CTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGG
CCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCC
TGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCC

>54715_54715_7_MPI-ESYT1_MPI_chr15_75185143_ENST00000535694_ESYT1_chr12_56537606_ENST00000267113_length(amino acids)=117AA_BP=
MWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEM

--------------------------------------------------------------
>54715_54715_8_MPI-ESYT1_MPI_chr15_75185143_ENST00000535694_ESYT1_chr12_56537606_ENST00000394048_length(transcript)=1240nt_BP=391nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTT
GACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGC
AACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCAC
CTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGG
CCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCC
TGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCC
CTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGAGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTAT
CCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTGCACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCCT
TCTGTATCTGTGCCTGGCCAGTGGCAGCACTAGCAGTGGTATTAGCTTATGCCAAATACAGCTTTGGAAGGATCTTTTTTTCTTTAACTA
GATGGTCACCTTCTTCCCTACCACACATGGGTGGGAAGGTGGACAGGCTAACCTCTCCAGCTGTGAGCCTCTTAGACTACTGCATGTAGC
AAATGTTCAGCAGCTCAGGCCCCCATGTCCAGTTCTGTCCCCACTGTCCTCAACCCTGTCCTGAAAATTCTACTGCTTTGATGGCTGGGG
CCAGTCTCTTGTCACTTTGGAAACTGAGGACGCGTGGATTCTACTCAAGCCTCCAAGTAGTGGCATATCAGTCTTGGAGCTCCTAGCTGG
TGATACGGAGAGGGCTTTGGAGGACTTGGGACAGCAGGGCCAATTTTTTTGCCCAAGTGCCTAGGCTGCTAACTCACTGACTAGAACTTA

>54715_54715_8_MPI-ESYT1_MPI_chr15_75185143_ENST00000535694_ESYT1_chr12_56537606_ENST00000394048_length(amino acids)=117AA_BP=
MWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEM

--------------------------------------------------------------
>54715_54715_9_MPI-ESYT1_MPI_chr15_75185143_ENST00000535694_ESYT1_chr12_56537606_ENST00000541590_length(transcript)=760nt_BP=391nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTT
GACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGC
AACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCAC
CTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGG
CCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCC
TGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCC
CTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGAGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTAT
CCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTGCACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCCT

>54715_54715_9_MPI-ESYT1_MPI_chr15_75185143_ENST00000535694_ESYT1_chr12_56537606_ENST00000541590_length(amino acids)=117AA_BP=
MWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEM

--------------------------------------------------------------
>54715_54715_10_MPI-ESYT1_MPI_chr15_75185143_ENST00000562606_ESYT1_chr12_56537606_ENST00000267113_length(transcript)=701nt_BP=482nt
ATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGCAGTATGCCTGGGGGAAGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGC
CAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCT
TGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGG
CAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCA
CCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCG
GCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGC
CTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGC

>54715_54715_10_MPI-ESYT1_MPI_chr15_75185143_ENST00000562606_ESYT1_chr12_56537606_ENST00000267113_length(amino acids)=145AA_BP=
MGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQ

--------------------------------------------------------------
>54715_54715_11_MPI-ESYT1_MPI_chr15_75185143_ENST00000562606_ESYT1_chr12_56537606_ENST00000394048_length(transcript)=1331nt_BP=482nt
ATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGCAGTATGCCTGGGGGAAGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGC
CAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCT
TGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGG
CAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCA
CCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCG
GCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGC
CTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGC
CCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGAGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTA
TCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTGCACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCC
TTCTGTATCTGTGCCTGGCCAGTGGCAGCACTAGCAGTGGTATTAGCTTATGCCAAATACAGCTTTGGAAGGATCTTTTTTTCTTTAACT
AGATGGTCACCTTCTTCCCTACCACACATGGGTGGGAAGGTGGACAGGCTAACCTCTCCAGCTGTGAGCCTCTTAGACTACTGCATGTAG
CAAATGTTCAGCAGCTCAGGCCCCCATGTCCAGTTCTGTCCCCACTGTCCTCAACCCTGTCCTGAAAATTCTACTGCTTTGATGGCTGGG
GCCAGTCTCTTGTCACTTTGGAAACTGAGGACGCGTGGATTCTACTCAAGCCTCCAAGTAGTGGCATATCAGTCTTGGAGCTCCTAGCTG
GTGATACGGAGAGGGCTTTGGAGGACTTGGGACAGCAGGGCCAATTTTTTTGCCCAAGTGCCTAGGCTGCTAACTCACTGACTAGAACTT

>54715_54715_11_MPI-ESYT1_MPI_chr15_75185143_ENST00000562606_ESYT1_chr12_56537606_ENST00000394048_length(amino acids)=145AA_BP=
MGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQ

--------------------------------------------------------------
>54715_54715_12_MPI-ESYT1_MPI_chr15_75185143_ENST00000562606_ESYT1_chr12_56537606_ENST00000541590_length(transcript)=851nt_BP=482nt
ATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGCAGTATGCCTGGGGGAAGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGC
CAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCT
TGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGG
CAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCA
CCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCG
GCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGC
CTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGC
CCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGAGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTA
TCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTGCACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCC

>54715_54715_12_MPI-ESYT1_MPI_chr15_75185143_ENST00000562606_ESYT1_chr12_56537606_ENST00000541590_length(amino acids)=145AA_BP=
MGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQ

--------------------------------------------------------------
>54715_54715_13_MPI-ESYT1_MPI_chr15_75185143_ENST00000563422_ESYT1_chr12_56537606_ENST00000267113_length(transcript)=738nt_BP=519nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGA
AGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGT
GGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGG
ACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCC
AGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCA
TTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAA
GGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGA
TGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAG

>54715_54715_13_MPI-ESYT1_MPI_chr15_75185143_ENST00000563422_ESYT1_chr12_56537606_ENST00000267113_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------
>54715_54715_14_MPI-ESYT1_MPI_chr15_75185143_ENST00000563422_ESYT1_chr12_56537606_ENST00000394048_length(transcript)=1368nt_BP=519nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGA
AGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGT
GGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGG
ACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCC
AGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCA
TTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAA
GGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGA
TGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAG
AGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCT
GCACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCCTTCTGTATCTGTGCCTGGCCAGTGGCAGCACTAGCAGTGGTATTAGCTTATGC
CAAATACAGCTTTGGAAGGATCTTTTTTTCTTTAACTAGATGGTCACCTTCTTCCCTACCACACATGGGTGGGAAGGTGGACAGGCTAAC
CTCTCCAGCTGTGAGCCTCTTAGACTACTGCATGTAGCAAATGTTCAGCAGCTCAGGCCCCCATGTCCAGTTCTGTCCCCACTGTCCTCA
ACCCTGTCCTGAAAATTCTACTGCTTTGATGGCTGGGGCCAGTCTCTTGTCACTTTGGAAACTGAGGACGCGTGGATTCTACTCAAGCCT
CCAAGTAGTGGCATATCAGTCTTGGAGCTCCTAGCTGGTGATACGGAGAGGGCTTTGGAGGACTTGGGACAGCAGGGCCAATTTTTTTGC
CCAAGTGCCTAGGCTGCTAACTCACTGACTAGAACTTAATCTGGTACTTTACAGTTTTGCACCAACTCTGCCAAGCCACTGGATCTTACA

>54715_54715_14_MPI-ESYT1_MPI_chr15_75185143_ENST00000563422_ESYT1_chr12_56537606_ENST00000394048_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------
>54715_54715_15_MPI-ESYT1_MPI_chr15_75185143_ENST00000563422_ESYT1_chr12_56537606_ENST00000541590_length(transcript)=888nt_BP=519nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGA
AGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGT
GGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGG
ACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCC
AGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCA
TTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAA
GGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGA
TGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAG
AGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCT

>54715_54715_15_MPI-ESYT1_MPI_chr15_75185143_ENST00000563422_ESYT1_chr12_56537606_ENST00000541590_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------
>54715_54715_16_MPI-ESYT1_MPI_chr15_75185143_ENST00000563786_ESYT1_chr12_56537606_ENST00000267113_length(transcript)=827nt_BP=608nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTGAGCACCCCCAGCTCTTGCCTGGTTTCCCGGGACACTAGGG
TGGGGCCTGAGGAGTGGAGTGGCAGCTGACCCTGTCTGTGCCCCTAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGAA
GATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTG
GATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGA
CAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCA
GGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCAT
TGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAG
GACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGAT
GAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGA

>54715_54715_16_MPI-ESYT1_MPI_chr15_75185143_ENST00000563786_ESYT1_chr12_56537606_ENST00000267113_length(amino acids)=167AA_BP=
MTLSVPLVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKD

--------------------------------------------------------------
>54715_54715_17_MPI-ESYT1_MPI_chr15_75185143_ENST00000563786_ESYT1_chr12_56537606_ENST00000394048_length(transcript)=1457nt_BP=608nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTGAGCACCCCCAGCTCTTGCCTGGTTTCCCGGGACACTAGGG
TGGGGCCTGAGGAGTGGAGTGGCAGCTGACCCTGTCTGTGCCCCTAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGAA
GATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTG
GATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGA
CAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCA
GGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCAT
TGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAG
GACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGAT
GAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGA
GAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTG
CACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCCTTCTGTATCTGTGCCTGGCCAGTGGCAGCACTAGCAGTGGTATTAGCTTATGCC
AAATACAGCTTTGGAAGGATCTTTTTTTCTTTAACTAGATGGTCACCTTCTTCCCTACCACACATGGGTGGGAAGGTGGACAGGCTAACC
TCTCCAGCTGTGAGCCTCTTAGACTACTGCATGTAGCAAATGTTCAGCAGCTCAGGCCCCCATGTCCAGTTCTGTCCCCACTGTCCTCAA
CCCTGTCCTGAAAATTCTACTGCTTTGATGGCTGGGGCCAGTCTCTTGTCACTTTGGAAACTGAGGACGCGTGGATTCTACTCAAGCCTC
CAAGTAGTGGCATATCAGTCTTGGAGCTCCTAGCTGGTGATACGGAGAGGGCTTTGGAGGACTTGGGACAGCAGGGCCAATTTTTTTGCC
CAAGTGCCTAGGCTGCTAACTCACTGACTAGAACTTAATCTGGTACTTTACAGTTTTGCACCAACTCTGCCAAGCCACTGGATCTTACAT

>54715_54715_17_MPI-ESYT1_MPI_chr15_75185143_ENST00000563786_ESYT1_chr12_56537606_ENST00000394048_length(amino acids)=167AA_BP=
MTLSVPLVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKD

--------------------------------------------------------------
>54715_54715_18_MPI-ESYT1_MPI_chr15_75185143_ENST00000563786_ESYT1_chr12_56537606_ENST00000541590_length(transcript)=977nt_BP=608nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTGAGCACCCCCAGCTCTTGCCTGGTTTCCCGGGACACTAGGG
TGGGGCCTGAGGAGTGGAGTGGCAGCTGACCCTGTCTGTGCCCCTAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGAA
GATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTG
GATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGA
CAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCA
GGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCAT
TGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAG
GACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGAT
GAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGA
GAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTG

>54715_54715_18_MPI-ESYT1_MPI_chr15_75185143_ENST00000563786_ESYT1_chr12_56537606_ENST00000541590_length(amino acids)=167AA_BP=
MTLSVPLVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKD

--------------------------------------------------------------
>54715_54715_19_MPI-ESYT1_MPI_chr15_75185143_ENST00000564003_ESYT1_chr12_56537606_ENST00000267113_length(transcript)=610nt_BP=391nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTT
GACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGC
AACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCAC
CTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGG
CCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCC
TGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCC

>54715_54715_19_MPI-ESYT1_MPI_chr15_75185143_ENST00000564003_ESYT1_chr12_56537606_ENST00000267113_length(amino acids)=117AA_BP=
MWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEM

--------------------------------------------------------------
>54715_54715_20_MPI-ESYT1_MPI_chr15_75185143_ENST00000564003_ESYT1_chr12_56537606_ENST00000394048_length(transcript)=1240nt_BP=391nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTT
GACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGC
AACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCAC
CTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGG
CCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCC
TGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCC
CTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGAGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTAT
CCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTGCACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCCT
TCTGTATCTGTGCCTGGCCAGTGGCAGCACTAGCAGTGGTATTAGCTTATGCCAAATACAGCTTTGGAAGGATCTTTTTTTCTTTAACTA
GATGGTCACCTTCTTCCCTACCACACATGGGTGGGAAGGTGGACAGGCTAACCTCTCCAGCTGTGAGCCTCTTAGACTACTGCATGTAGC
AAATGTTCAGCAGCTCAGGCCCCCATGTCCAGTTCTGTCCCCACTGTCCTCAACCCTGTCCTGAAAATTCTACTGCTTTGATGGCTGGGG
CCAGTCTCTTGTCACTTTGGAAACTGAGGACGCGTGGATTCTACTCAAGCCTCCAAGTAGTGGCATATCAGTCTTGGAGCTCCTAGCTGG
TGATACGGAGAGGGCTTTGGAGGACTTGGGACAGCAGGGCCAATTTTTTTGCCCAAGTGCCTAGGCTGCTAACTCACTGACTAGAACTTA

>54715_54715_20_MPI-ESYT1_MPI_chr15_75185143_ENST00000564003_ESYT1_chr12_56537606_ENST00000394048_length(amino acids)=117AA_BP=
MWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEM

--------------------------------------------------------------
>54715_54715_21_MPI-ESYT1_MPI_chr15_75185143_ENST00000564003_ESYT1_chr12_56537606_ENST00000541590_length(transcript)=760nt_BP=391nt
ATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTTGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTT
GACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGC
AACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCAC
CTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGG
CCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCC
TGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCC
CTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGAGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTAT
CCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTGCACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCCT

>54715_54715_21_MPI-ESYT1_MPI_chr15_75185143_ENST00000564003_ESYT1_chr12_56537606_ENST00000541590_length(amino acids)=117AA_BP=
MWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTFNGNLPFLFKVLSVETPLSIQAHPNKELAEKLHLQAPQHYPDANHKPEM

--------------------------------------------------------------
>54715_54715_22_MPI-ESYT1_MPI_chr15_75185143_ENST00000565576_ESYT1_chr12_56537606_ENST00000267113_length(transcript)=718nt_BP=499nt
CAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGAAGATGGGTTCCAACAGCGAA
GTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTGGATGGGGACTCACCCCCGA
GGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTC
AAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAG
CTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAG
GGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGG
AGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCC

>54715_54715_22_MPI-ESYT1_MPI_chr15_75185143_ENST00000565576_ESYT1_chr12_56537606_ENST00000267113_length(amino acids)=165AA_BP=
MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTF

--------------------------------------------------------------
>54715_54715_23_MPI-ESYT1_MPI_chr15_75185143_ENST00000565576_ESYT1_chr12_56537606_ENST00000394048_length(transcript)=1348nt_BP=499nt
CAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGAAGATGGGTTCCAACAGCGAA
GTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTGGATGGGGACTCACCCCCGA
GGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTC
AAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAG
CTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAG
GGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGG
AGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCC
AAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGAGAAGAACCGTATGTTCCCT
TTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTGCACATTGTTCTCCCTTCCT
CCCAACTCCTCAGGGCCTTCTGTATCTGTGCCTGGCCAGTGGCAGCACTAGCAGTGGTATTAGCTTATGCCAAATACAGCTTTGGAAGGA
TCTTTTTTTCTTTAACTAGATGGTCACCTTCTTCCCTACCACACATGGGTGGGAAGGTGGACAGGCTAACCTCTCCAGCTGTGAGCCTCT
TAGACTACTGCATGTAGCAAATGTTCAGCAGCTCAGGCCCCCATGTCCAGTTCTGTCCCCACTGTCCTCAACCCTGTCCTGAAAATTCTA
CTGCTTTGATGGCTGGGGCCAGTCTCTTGTCACTTTGGAAACTGAGGACGCGTGGATTCTACTCAAGCCTCCAAGTAGTGGCATATCAGT
CTTGGAGCTCCTAGCTGGTGATACGGAGAGGGCTTTGGAGGACTTGGGACAGCAGGGCCAATTTTTTTGCCCAAGTGCCTAGGCTGCTAA

>54715_54715_23_MPI-ESYT1_MPI_chr15_75185143_ENST00000565576_ESYT1_chr12_56537606_ENST00000394048_length(amino acids)=165AA_BP=
MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTF

--------------------------------------------------------------
>54715_54715_24_MPI-ESYT1_MPI_chr15_75185143_ENST00000565576_ESYT1_chr12_56537606_ENST00000541590_length(transcript)=868nt_BP=499nt
CAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGGGGAAGATGGGTTCCAACAGCGAA
GTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGTTGTGGATGGGGACTCACCCCCGA
GGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACCAGGACAGCTTGGGCTCAAAGGTC
AAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCATCCAGGCACACCCTAACAAGGAG
CTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGGCCATTGCCCTCACCCCCTTCCAG
GGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAACAAGGACAAGGGCAGCTCCTAGG
AGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATGTGATGAGCCTAAAGCTAGGGTCC
AAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCAAAGAGAAGAACCGTATGTTCCCT
TTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTGCCTGCACATTGTTCTCCCTTCCT

>54715_54715_24_MPI-ESYT1_MPI_chr15_75185143_ENST00000565576_ESYT1_chr12_56537606_ENST00000541590_length(amino acids)=165AA_BP=
MAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGSKVKDTF

--------------------------------------------------------------
>54715_54715_25_MPI-ESYT1_MPI_chr15_75185143_ENST00000566377_ESYT1_chr12_56537606_ENST00000267113_length(transcript)=741nt_BP=522nt
GGCATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGG
GGAAGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGT
TGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACC
AGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCA
TCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGG
CCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAA
CAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATG
TGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCA

>54715_54715_25_MPI-ESYT1_MPI_chr15_75185143_ENST00000566377_ESYT1_chr12_56537606_ENST00000267113_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------
>54715_54715_26_MPI-ESYT1_MPI_chr15_75185143_ENST00000566377_ESYT1_chr12_56537606_ENST00000394048_length(transcript)=1371nt_BP=522nt
GGCATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGG
GGAAGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGT
TGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACC
AGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCA
TCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGG
CCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAA
CAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATG
TGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCA
AAGAGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTG
CCTGCACATTGTTCTCCCTTCCTCCCAACTCCTCAGGGCCTTCTGTATCTGTGCCTGGCCAGTGGCAGCACTAGCAGTGGTATTAGCTTA
TGCCAAATACAGCTTTGGAAGGATCTTTTTTTCTTTAACTAGATGGTCACCTTCTTCCCTACCACACATGGGTGGGAAGGTGGACAGGCT
AACCTCTCCAGCTGTGAGCCTCTTAGACTACTGCATGTAGCAAATGTTCAGCAGCTCAGGCCCCCATGTCCAGTTCTGTCCCCACTGTCC
TCAACCCTGTCCTGAAAATTCTACTGCTTTGATGGCTGGGGCCAGTCTCTTGTCACTTTGGAAACTGAGGACGCGTGGATTCTACTCAAG
CCTCCAAGTAGTGGCATATCAGTCTTGGAGCTCCTAGCTGGTGATACGGAGAGGGCTTTGGAGGACTTGGGACAGCAGGGCCAATTTTTT
TGCCCAAGTGCCTAGGCTGCTAACTCACTGACTAGAACTTAATCTGGTACTTTACAGTTTTGCACCAACTCTGCCAAGCCACTGGATCTT

>54715_54715_26_MPI-ESYT1_MPI_chr15_75185143_ENST00000566377_ESYT1_chr12_56537606_ENST00000394048_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------
>54715_54715_27_MPI-ESYT1_MPI_chr15_75185143_ENST00000566377_ESYT1_chr12_56537606_ENST00000541590_length(transcript)=891nt_BP=522nt
GGCATACGTGCTTAATCCTGGTGCAGGGGGCGAGCATGGCCGCTCCGCGAGTATTCCCACTTTCCTGTGCGGTGCAGCAGTATGCCTGGG
GGAAGATGGGTTCCAACAGCGAAGTGGCGCGGCTGTTGGCCAGCAGTGATCCACTGGCCCAGATCGCAGAGGACAAGCCTTATGCAGAGT
TGTGGATGGGGACTCACCCCCGAGGGGATGCCAAGATCCTTGACAACCGCATCTCACAGAAGACCCTAAGCCAGTGGATTGCTGAGAACC
AGGACAGCTTGGGCTCAAAGGTCAAGGACACCTTTAATGGCAACCTGCCCTTCCTCTTCAAAGTGCTCTCAGTTGAAACACCCCTGTCCA
TCCAGGCACACCCTAACAAGGAGCTGGCAGAGAAGCTGCACCTCCAGGCTCCGCAGCACTACCCCGATGCCAACCACAAGCCAGAGATGG
CCATTGCCCTCACCCCCTTCCAGGGCTTGTGTGGCTTCCGGCCAGTTGAGGAGATTGTAACCTTTCTAAAGAGTATGACCTGATGGACAA
CAAGGACAAGGGCAGCTCCTAGGAGCTGGCGAGTCCCAGCCTGACTGCTCTGTCTTCCTGCCTTCGTCTCGCTCCATCACCGCCTCAATG
TGATGAGCCTAAAGCTAGGGTCCAAGGGCAGAGCCTGTGCCCTTCAGCCCTTTCACCTAACAGGCCCATATTCGGGCCTTTGCCTGACCA
AAGAGAAGAACCGTATGTTCCCTTTACTGCACGGCCTTTATCCTTCTGGGCCCCTGGGGCGGGGACCTGAGCTGGCTGTTTCCTGCTTTG

>54715_54715_27_MPI-ESYT1_MPI_chr15_75185143_ENST00000566377_ESYT1_chr12_56537606_ENST00000541590_length(amino acids)=171AA_BP=
MVQGASMAAPRVFPLSCAVQQYAWGKMGSNSEVARLLASSDPLAQIAEDKPYAELWMGTHPRGDAKILDNRISQKTLSQWIAENQDSLGS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for MPI-ESYT1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for MPI-ESYT1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for MPI-ESYT1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource