FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:MROH1-XRCC5 (FusionGDB2 ID:54887)

Fusion Gene Summary for MROH1-XRCC5

check button Fusion gene summary
Fusion gene informationFusion gene name: MROH1-XRCC5
Fusion gene ID: 54887
HgeneTgene
Gene symbol

MROH1

XRCC5

Gene ID

727957

7520

Gene namemaestro heat like repeat family member 1X-ray repair cross complementing 5
SynonymsHEATR7AKARP-1|KARP1|KU80|KUB2|Ku86|NFIV
Cytomap

8q24.3

2q35

Type of geneprotein-codingprotein-coding
Descriptionmaestro heat-like repeat-containing protein family member 1HEAT repeat containing 7AHEAT repeat-containing protein 7AX-ray repair cross-complementing protein 586 kDa subunit of Ku antigenATP-dependent DNA helicase 2 subunit 2ATP-dependent DNA helicase II 80 kDa subunitCTC box-binding factor 85 kDa subunitCTC85CTCBFDNA repair protein XRCC5Ku autoantigen, 80kDaKu
Modification date2020032020200313
UniProtAcc

Q8NDA8

.
Ensembl transtripts involved in fusion geneENST00000527071, ENST00000326134, 
ENST00000398656, ENST00000423230, 
ENST00000528919, ENST00000534366, 
ENST00000544576, 		ENST00000392132, 
ENST00000392133, ENST00000471649, 
Fusion gene scores* DoF score18 X 8 X 8=11529 X 6 X 5=270
# samples 1910
** MAII scorelog2(19/1152*10)=-2.60006939311136
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/270*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MROH1 [Title/Abstract] AND XRCC5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMROH1(145255444)-XRCC5(217054948), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneXRCC5

GO:0002218

activation of innate immune response

28712728

TgeneXRCC5

GO:0006303

double-strand break repair via nonhomologous end joining

26359349

TgeneXRCC5

GO:0045860

positive regulation of protein kinase activity

22504299

TgeneXRCC5

GO:0071480

cellular response to gamma radiation

26359349


check buttonFusion gene breakpoints across MROH1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across XRCC5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-23-1030-01AMROH1chr8

145255444

+XRCC5chr2

217054948

+


Top

Fusion Gene ORF analysis for MROH1-XRCC5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000527071ENST00000392132MROH1chr8

145255444

+XRCC5chr2

217054948

+
3UTR-3CDSENST00000527071ENST00000392133MROH1chr8

145255444

+XRCC5chr2

217054948

+
3UTR-intronENST00000527071ENST00000471649MROH1chr8

145255444

+XRCC5chr2

217054948

+
5CDS-intronENST00000326134ENST00000471649MROH1chr8

145255444

+XRCC5chr2

217054948

+
5CDS-intronENST00000398656ENST00000471649MROH1chr8

145255444

+XRCC5chr2

217054948

+
5CDS-intronENST00000423230ENST00000471649MROH1chr8

145255444

+XRCC5chr2

217054948

+
5CDS-intronENST00000528919ENST00000471649MROH1chr8

145255444

+XRCC5chr2

217054948

+
5CDS-intronENST00000534366ENST00000471649MROH1chr8

145255444

+XRCC5chr2

217054948

+
In-frameENST00000326134ENST00000392132MROH1chr8

145255444

+XRCC5chr2

217054948

+
In-frameENST00000326134ENST00000392133MROH1chr8

145255444

+XRCC5chr2

217054948

+
In-frameENST00000398656ENST00000392132MROH1chr8

145255444

+XRCC5chr2

217054948

+
In-frameENST00000398656ENST00000392133MROH1chr8

145255444

+XRCC5chr2

217054948

+
In-frameENST00000423230ENST00000392132MROH1chr8

145255444

+XRCC5chr2

217054948

+
In-frameENST00000423230ENST00000392133MROH1chr8

145255444

+XRCC5chr2

217054948

+
In-frameENST00000528919ENST00000392132MROH1chr8

145255444

+XRCC5chr2

217054948

+
In-frameENST00000528919ENST00000392133MROH1chr8

145255444

+XRCC5chr2

217054948

+
In-frameENST00000534366ENST00000392132MROH1chr8

145255444

+XRCC5chr2

217054948

+
In-frameENST00000534366ENST00000392133MROH1chr8

145255444

+XRCC5chr2

217054948

+
intron-3CDSENST00000544576ENST00000392132MROH1chr8

145255444

+XRCC5chr2

217054948

+
intron-3CDSENST00000544576ENST00000392133MROH1chr8

145255444

+XRCC5chr2

217054948

+
intron-intronENST00000544576ENST00000471649MROH1chr8

145255444

+XRCC5chr2

217054948

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000423230MROH1chr8145255444+ENST00000392133XRCC5chr2217054948+27041238971602501
ENST00000423230MROH1chr8145255444+ENST00000392132XRCC5chr2217054948+26921238971602501
ENST00000398656MROH1chr8145255444+ENST00000392133XRCC5chr2217054948+27041238971602501
ENST00000398656MROH1chr8145255444+ENST00000392132XRCC5chr2217054948+26921238971602501
ENST00000534366MROH1chr8145255444+ENST00000392133XRCC5chr2217054948+273112651241629501
ENST00000534366MROH1chr8145255444+ENST00000392132XRCC5chr2217054948+271912651241629501
ENST00000528919MROH1chr8145255444+ENST00000392133XRCC5chr2217054948+27281262371626529
ENST00000528919MROH1chr8145255444+ENST00000392132XRCC5chr2217054948+27161262371626529
ENST00000326134MROH1chr8145255444+ENST00000392133XRCC5chr2217054948+26641198571562501
ENST00000326134MROH1chr8145255444+ENST00000392132XRCC5chr2217054948+26521198571562501

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000423230ENST00000392133MROH1chr8145255444+XRCC5chr2217054948+0.0018315710.99816835
ENST00000423230ENST00000392132MROH1chr8145255444+XRCC5chr2217054948+0.0017993140.99820065
ENST00000398656ENST00000392133MROH1chr8145255444+XRCC5chr2217054948+0.0018315710.99816835
ENST00000398656ENST00000392132MROH1chr8145255444+XRCC5chr2217054948+0.0017993140.99820065
ENST00000534366ENST00000392133MROH1chr8145255444+XRCC5chr2217054948+0.0018721310.9981279
ENST00000534366ENST00000392132MROH1chr8145255444+XRCC5chr2217054948+0.0018334010.99816656
ENST00000528919ENST00000392133MROH1chr8145255444+XRCC5chr2217054948+0.0018577640.99814224
ENST00000528919ENST00000392132MROH1chr8145255444+XRCC5chr2217054948+0.00183730.9981627
ENST00000326134ENST00000392133MROH1chr8145255444+XRCC5chr2217054948+0.001688270.99831176
ENST00000326134ENST00000392132MROH1chr8145255444+XRCC5chr2217054948+0.0016503490.99834967

Top

Fusion Genomic Features for MROH1-XRCC5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for MROH1-XRCC5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:145255444/chr2:217054948)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MROH1

Q8NDA8

.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMROH1chr8:145255444chr2:217054948ENST00000326134+1042159_1983801642.0RepeatNote=HEAT 2
HgeneMROH1chr8:145255444chr2:217054948ENST00000326134+1042344_3823801642.0RepeatNote=HEAT 3
HgeneMROH1chr8:145255444chr2:217054948ENST00000326134+10423_413801642.0RepeatNote=HEAT 1
HgeneMROH1chr8:145255444chr2:217054948ENST00000398656+1143159_1983801642.0RepeatNote=HEAT 2
HgeneMROH1chr8:145255444chr2:217054948ENST00000398656+1143344_3823801642.0RepeatNote=HEAT 3
HgeneMROH1chr8:145255444chr2:217054948ENST00000398656+11433_413801642.0RepeatNote=HEAT 1
HgeneMROH1chr8:145255444chr2:217054948ENST00000423230+1112159_198380423.0RepeatNote=HEAT 2
HgeneMROH1chr8:145255444chr2:217054948ENST00000423230+1112344_382380423.0RepeatNote=HEAT 3
HgeneMROH1chr8:145255444chr2:217054948ENST00000423230+11123_41380423.0RepeatNote=HEAT 1
HgeneMROH1chr8:145255444chr2:217054948ENST00000528919+1143159_1983801642.0RepeatNote=HEAT 2
HgeneMROH1chr8:145255444chr2:217054948ENST00000528919+1143344_3823801642.0RepeatNote=HEAT 3
HgeneMROH1chr8:145255444chr2:217054948ENST00000528919+11433_413801642.0RepeatNote=HEAT 1
TgeneXRCC5chr8:145255444chr2:217054948ENST000003921321521720_728611733.0MotifNote=EEXXXDL motif
TgeneXRCC5chr8:145255444chr2:217054948ENST000003921331723720_728611733.0MotifNote=EEXXXDL motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneMROH1chr8:145255444chr2:217054948ENST00000326134+10421048_10863801642.0RepeatNote=HEAT 5
HgeneMROH1chr8:145255444chr2:217054948ENST00000326134+10421358_13963801642.0RepeatNote=HEAT 6
HgeneMROH1chr8:145255444chr2:217054948ENST00000326134+10421605_16413801642.0RepeatNote=HEAT 7
HgeneMROH1chr8:145255444chr2:217054948ENST00000326134+1042385_4233801642.0RepeatNote=HEAT 4
HgeneMROH1chr8:145255444chr2:217054948ENST00000398656+11431048_10863801642.0RepeatNote=HEAT 5
HgeneMROH1chr8:145255444chr2:217054948ENST00000398656+11431358_13963801642.0RepeatNote=HEAT 6
HgeneMROH1chr8:145255444chr2:217054948ENST00000398656+11431605_16413801642.0RepeatNote=HEAT 7
HgeneMROH1chr8:145255444chr2:217054948ENST00000398656+1143385_4233801642.0RepeatNote=HEAT 4
HgeneMROH1chr8:145255444chr2:217054948ENST00000423230+11121048_1086380423.0RepeatNote=HEAT 5
HgeneMROH1chr8:145255444chr2:217054948ENST00000423230+11121358_1396380423.0RepeatNote=HEAT 6
HgeneMROH1chr8:145255444chr2:217054948ENST00000423230+11121605_1641380423.0RepeatNote=HEAT 7
HgeneMROH1chr8:145255444chr2:217054948ENST00000423230+1112385_423380423.0RepeatNote=HEAT 4
HgeneMROH1chr8:145255444chr2:217054948ENST00000528919+11431048_10863801642.0RepeatNote=HEAT 5
HgeneMROH1chr8:145255444chr2:217054948ENST00000528919+11431358_13963801642.0RepeatNote=HEAT 6
HgeneMROH1chr8:145255444chr2:217054948ENST00000528919+11431605_16413801642.0RepeatNote=HEAT 7
HgeneMROH1chr8:145255444chr2:217054948ENST00000528919+1143385_4233801642.0RepeatNote=HEAT 4
HgeneMROH1chr8:145255444chr2:217054948ENST00000544576+1261048_10860616.0RepeatNote=HEAT 5
HgeneMROH1chr8:145255444chr2:217054948ENST00000544576+1261358_13960616.0RepeatNote=HEAT 6
HgeneMROH1chr8:145255444chr2:217054948ENST00000544576+126159_1980616.0RepeatNote=HEAT 2
HgeneMROH1chr8:145255444chr2:217054948ENST00000544576+1261605_16410616.0RepeatNote=HEAT 7
HgeneMROH1chr8:145255444chr2:217054948ENST00000544576+126344_3820616.0RepeatNote=HEAT 3
HgeneMROH1chr8:145255444chr2:217054948ENST00000544576+126385_4230616.0RepeatNote=HEAT 4
HgeneMROH1chr8:145255444chr2:217054948ENST00000544576+1263_410616.0RepeatNote=HEAT 1
TgeneXRCC5chr8:145255444chr2:217054948ENST000003921321521478_519611733.0Compositional biasNote=Pro-rich
TgeneXRCC5chr8:145255444chr2:217054948ENST000003921331723478_519611733.0Compositional biasNote=Pro-rich
TgeneXRCC5chr8:145255444chr2:217054948ENST000003921321521251_460611733.0DomainNote=Ku
TgeneXRCC5chr8:145255444chr2:217054948ENST000003921331723251_460611733.0DomainNote=Ku
TgeneXRCC5chr8:145255444chr2:217054948ENST000003921321521138_165611733.0RegionNote=Leucine-zipper
TgeneXRCC5chr8:145255444chr2:217054948ENST000003921331723138_165611733.0RegionNote=Leucine-zipper


Top

Fusion Gene Sequence for MROH1-XRCC5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>54887_54887_1_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000326134_XRCC5_chr2_217054948_ENST00000392132_length(transcript)=2652nt_BP=1198nt
GATGGGAGAAGAAGTTGTCCATGTTCACACTGGGTGAAGGAAGCTGAAACCACAGACATGACTGAGTCCTCCATGAAGAAGCTGGCCTCC
ACCCTGCTGGACGCCATCACCGATAAGGACCCCCTGGTGCAGGAGCAGGTCTGCAGTGCCCTGTGCTCCCTCGGGGAGGCGCGGCCGGTG
GAGACGCTCCGTGCCTGCGAGGAGTATCTGCGGCAGCATGACAAGCTGGCACACCCATACCGAGCAGCGGTCCTGAGGGCCATGGAGAGG
GTCCTGAGCAGTCGCGCCAGTGAGCTGGACAAGGACACAGCCAGCACCATCATCCTCCTGGCCTCCAGCGAGATGACCAAGACGAAGGAC
CTGGTCTGGGACTGGCAGCAGGCGGCGAGTGGCGTCCTGGTGGCCGTGGGAAGACAGTTCATCAGCAAGGTGATGGAGGAGCTGCTGCGC
AGGCTGCACCCTGGGACCCTGCCACACTGCGCCGTGCTGCACACCCTCGCCAGCCTCTCGGTGGCCAACGCGTTCGGCGTAGTCCCCTTC
CTGCCATCCGTCCTGAGCTCCCTGCTGCCCGTGCTGGGCGTGGCCAAGCAGGACACGGTGCGCGTGGCCTTCTGCTCCGCTCTGCAGCGC
TTCAGCGAGGGTGCCCTGGAGTACCTAGCCAACCTGGACCGAGCCCCAGACCCCACGGTCAGGAAGGACGCCTTTGCCACCGACATCTTC
AGCGCCTACGATGTTCTCTTCCATCAGTGGCTGCAGAGTCGAGAAGCCAAGCTCCGTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGC
CATCTGCTGCCCAGTGAGAGGCTGGAAGAGCAGCTGCCCAAGCTCCTCCCTGGGATTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTC
TACTTGTCCAAGAGCCTGGGCCAGATCCTCGAGGCAGCTGTGAGTGTGGGCAGCCGCACACTGGAGACCCAGCTGGATGCCCTCTTGGCT
GCACTGCACTCCCAGATCTGTGTGCCTGTGGAGTCCTCAAGCCCCCTGGTGATGAGTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTG
CTGGCCTGCAGCTCGCCTGACCGCCTACTGGCCTTCCTGCTGCCCAGGCTGGACACCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAG
GTGGTCAGACATGTCATCAACTCAGCTGCGAGTAACCAGCTCATAAATCACATCGAACAGTTTTTGGATACTAATGAAACACCGTATTTT
ATGAAGAGCATAGACTGCATCCGAGCCTTCCGGGAAGAAGCCATTAAGTTTTCAGAAGAGCAGCGCTTTAACAACTTCCTGAAAGCCCTT
CAAGAGAAAGTGGAAATTAAACAATTAAATCATTTCTGGGAAATTGTTGTCCAGGATGGAATTACTCTGATCACCAAAGAGGAAGCCTCT
GGAAGTTCTGTCACAGCTGAGGAAGCCAAAAAGTTTCTGGCCCCCAAAGACAAACCAAGTGGAGACACAGCAGCTGTATTTGAAGAAGGT
GGTGATGTGGACGATTTATTGGACATGATATAGGTCGTGGATGTATGGGGAATCTAAGAGAGCTGCCATCGCTGTGATGCTGGGAGTTCT
AACAAAACAAGTTGGATGCGGCCATTCAAGGGGAGCCAAAATCTCAAGAAATTCCCAGCAGGTTACCTGGAGGCGGATCATCTAATTCTC
TGTGGAATGAATACACACATATATATTACAAGGGATAATTTAGACCCCATACAAGTTTATAAAGAGTCATTGTTATTTTCTGGTTGGTGT
ATTATTTTTTCTGTGGTCTTACTGATCTTTGTATATTACATACATGCTTTGAAGTTTCTGGAAAGTAGATCTTTTCTTGACCTAGTATAT
CAGTGACAGTTGCAGCCCTTGTGATGTGATTAGTGTCTCATGTGGAACCATGGCATGGTTATTGATGAGTTTCTTAACCCTTTCCAGAGT
CCTCCTTTGCCTGATCCTCCAACAGCTGTCACAACTTGTGTTGAGCAAGCAGTAGCATTTGCTTCCTCCCAACAAGCAGCTGGGTTAGGA
AAACCATGGGTAAGGACGGACTCACTTCTCTTTTTAGTTGAGGCCTTCTAGTTACCACATTACTCTGCCTCTGTATATAGGTGGTTTTCT
TTAAGTGGGGTGGGAAGGGGAGCACAATTTCCCTTCATACTCCTTTTAAGCAGTGAGTTATGGTGGTGGTCTCATGAAGAAAAGACCTTT
TGGCCCAATCTCTGCCATATCAGTGAACCTTTAGAAACTCAAAAACTGAGAAATTTACTACAGTAGTTAGAATTATATCACTTCACTGTT
CTCTACTTGCAAGCCTCAAAGAGAGAAAGTTTCGTTATATTAAAACACTTAGGTAACTTTTCGGTCTTTCCCATTTCTACCTAAGTCAGC
TTTCATCTTTGTGGATGGTGTCTCCTTTACTAAATAAGAAAATAACAAAGCCCTTATTCTCTTTTTTTCTTGTCCTCATTCTTGCCTTGA
GTTCCAGTTCCTCTTTGGTGTACAGACTTCTTGGTACCCAGTCACCTCTGTCTTCAGCACCCTCATAAGTCGTCACTAATACACAGTTTT

>54887_54887_1_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000326134_XRCC5_chr2_217054948_ENST00000392132_length(amino acids)=501AA_BP=380
MTESSMKKLASTLLDAITDKDPLVQEQVCSALCSLGEARPVETLRACEEYLRQHDKLAHPYRAAVLRAMERVLSSRASELDKDTASTIIL
LASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDT
VRVAFCSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGI
LALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDT
SNERTRVGTLQVVRHVINSAASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQD

--------------------------------------------------------------
>54887_54887_2_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000326134_XRCC5_chr2_217054948_ENST00000392133_length(transcript)=2664nt_BP=1198nt
GATGGGAGAAGAAGTTGTCCATGTTCACACTGGGTGAAGGAAGCTGAAACCACAGACATGACTGAGTCCTCCATGAAGAAGCTGGCCTCC
ACCCTGCTGGACGCCATCACCGATAAGGACCCCCTGGTGCAGGAGCAGGTCTGCAGTGCCCTGTGCTCCCTCGGGGAGGCGCGGCCGGTG
GAGACGCTCCGTGCCTGCGAGGAGTATCTGCGGCAGCATGACAAGCTGGCACACCCATACCGAGCAGCGGTCCTGAGGGCCATGGAGAGG
GTCCTGAGCAGTCGCGCCAGTGAGCTGGACAAGGACACAGCCAGCACCATCATCCTCCTGGCCTCCAGCGAGATGACCAAGACGAAGGAC
CTGGTCTGGGACTGGCAGCAGGCGGCGAGTGGCGTCCTGGTGGCCGTGGGAAGACAGTTCATCAGCAAGGTGATGGAGGAGCTGCTGCGC
AGGCTGCACCCTGGGACCCTGCCACACTGCGCCGTGCTGCACACCCTCGCCAGCCTCTCGGTGGCCAACGCGTTCGGCGTAGTCCCCTTC
CTGCCATCCGTCCTGAGCTCCCTGCTGCCCGTGCTGGGCGTGGCCAAGCAGGACACGGTGCGCGTGGCCTTCTGCTCCGCTCTGCAGCGC
TTCAGCGAGGGTGCCCTGGAGTACCTAGCCAACCTGGACCGAGCCCCAGACCCCACGGTCAGGAAGGACGCCTTTGCCACCGACATCTTC
AGCGCCTACGATGTTCTCTTCCATCAGTGGCTGCAGAGTCGAGAAGCCAAGCTCCGTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGC
CATCTGCTGCCCAGTGAGAGGCTGGAAGAGCAGCTGCCCAAGCTCCTCCCTGGGATTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTC
TACTTGTCCAAGAGCCTGGGCCAGATCCTCGAGGCAGCTGTGAGTGTGGGCAGCCGCACACTGGAGACCCAGCTGGATGCCCTCTTGGCT
GCACTGCACTCCCAGATCTGTGTGCCTGTGGAGTCCTCAAGCCCCCTGGTGATGAGTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTG
CTGGCCTGCAGCTCGCCTGACCGCCTACTGGCCTTCCTGCTGCCCAGGCTGGACACCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAG
GTGGTCAGACATGTCATCAACTCAGCTGCGAGTAACCAGCTCATAAATCACATCGAACAGTTTTTGGATACTAATGAAACACCGTATTTT
ATGAAGAGCATAGACTGCATCCGAGCCTTCCGGGAAGAAGCCATTAAGTTTTCAGAAGAGCAGCGCTTTAACAACTTCCTGAAAGCCCTT
CAAGAGAAAGTGGAAATTAAACAATTAAATCATTTCTGGGAAATTGTTGTCCAGGATGGAATTACTCTGATCACCAAAGAGGAAGCCTCT
GGAAGTTCTGTCACAGCTGAGGAAGCCAAAAAGTTTCTGGCCCCCAAAGACAAACCAAGTGGAGACACAGCAGCTGTATTTGAAGAAGGT
GGTGATGTGGACGATTTATTGGACATGATATAGGTCGTGGATGTATGGGGAATCTAAGAGAGCTGCCATCGCTGTGATGCTGGGAGTTCT
AACAAAACAAGTTGGATGCGGCCATTCAAGGGGAGCCAAAATCTCAAGAAATTCCCAGCAGGTTACCTGGAGGCGGATCATCTAATTCTC
TGTGGAATGAATACACACATATATATTACAAGGGATAATTTAGACCCCATACAAGTTTATAAAGAGTCATTGTTATTTTCTGGTTGGTGT
ATTATTTTTTCTGTGGTCTTACTGATCTTTGTATATTACATACATGCTTTGAAGTTTCTGGAAAGTAGATCTTTTCTTGACCTAGTATAT
CAGTGACAGTTGCAGCCCTTGTGATGTGATTAGTGTCTCATGTGGAACCATGGCATGGTTATTGATGAGTTTCTTAACCCTTTCCAGAGT
CCTCCTTTGCCTGATCCTCCAACAGCTGTCACAACTTGTGTTGAGCAAGCAGTAGCATTTGCTTCCTCCCAACAAGCAGCTGGGTTAGGA
AAACCATGGGTAAGGACGGACTCACTTCTCTTTTTAGTTGAGGCCTTCTAGTTACCACATTACTCTGCCTCTGTATATAGGTGGTTTTCT
TTAAGTGGGGTGGGAAGGGGAGCACAATTTCCCTTCATACTCCTTTTAAGCAGTGAGTTATGGTGGTGGTCTCATGAAGAAAAGACCTTT
TGGCCCAATCTCTGCCATATCAGTGAACCTTTAGAAACTCAAAAACTGAGAAATTTACTACAGTAGTTAGAATTATATCACTTCACTGTT
CTCTACTTGCAAGCCTCAAAGAGAGAAAGTTTCGTTATATTAAAACACTTAGGTAACTTTTCGGTCTTTCCCATTTCTACCTAAGTCAGC
TTTCATCTTTGTGGATGGTGTCTCCTTTACTAAATAAGAAAATAACAAAGCCCTTATTCTCTTTTTTTCTTGTCCTCATTCTTGCCTTGA
GTTCCAGTTCCTCTTTGGTGTACAGACTTCTTGGTACCCAGTCACCTCTGTCTTCAGCACCCTCATAAGTCGTCACTAATACACAGTTTT

>54887_54887_2_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000326134_XRCC5_chr2_217054948_ENST00000392133_length(amino acids)=501AA_BP=380
MTESSMKKLASTLLDAITDKDPLVQEQVCSALCSLGEARPVETLRACEEYLRQHDKLAHPYRAAVLRAMERVLSSRASELDKDTASTIIL
LASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDT
VRVAFCSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGI
LALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDT
SNERTRVGTLQVVRHVINSAASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQD

--------------------------------------------------------------
>54887_54887_3_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000398656_XRCC5_chr2_217054948_ENST00000392132_length(transcript)=2692nt_BP=1238nt
GGGAAGGCGGCGCCCCGGCCGAGGTGGCGGCGGCTCCTCAGATGGGAGAAGAAGTTGTCCATGTTCACACTGGGTGAAGGAAGCTGAAAC
CACAGACATGACTGAGTCCTCCATGAAGAAGCTGGCCTCCACCCTGCTGGACGCCATCACCGATAAGGACCCCCTGGTGCAGGAGCAGGT
CTGCAGTGCCCTGTGCTCCCTCGGGGAGGCGCGGCCGGTGGAGACGCTCCGTGCCTGCGAGGAGTATCTGCGGCAGCATGACAAGCTGGC
ACACCCATACCGAGCAGCGGTCCTGAGGGCCATGGAGAGGGTCCTGAGCAGTCGCGCCAGTGAGCTGGACAAGGACACAGCCAGCACCAT
CATCCTCCTGGCCTCCAGCGAGATGACCAAGACGAAGGACCTGGTCTGGGACTGGCAGCAGGCGGCGAGTGGCGTCCTGGTGGCCGTGGG
AAGACAGTTCATCAGCAAGGTGATGGAGGAGCTGCTGCGCAGGCTGCACCCTGGGACCCTGCCACACTGCGCCGTGCTGCACACCCTCGC
CAGCCTCTCGGTGGCCAACGCGTTCGGCGTAGTCCCCTTCCTGCCATCCGTCCTGAGCTCCCTGCTGCCCGTGCTGGGCGTGGCCAAGCA
GGACACGGTGCGCGTGGCCTTCTGCTCCGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTACCTAGCCAACCTGGACCGAGCCCCAGA
CCCCACGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCATCAGTGGCTGCAGAGTCGAGAAGCCAA
GCTCCGTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCTGGAAGAGCAGCTGCCCAAGCTCCTCCC
TGGGATTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCAGATCCTCGAGGCAGCTGTGAGTGTGGG
CAGCCGCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGTGCCTGTGGAGTCCTCAAGCCCCCTGGT
GATGAGTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCGCCTACTGGCCTTCCTGCTGCCCAGGCT
GGACACCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTCAGCTGCGAGTAACCAGCTCATAAATCA
CATCGAACAGTTTTTGGATACTAATGAAACACCGTATTTTATGAAGAGCATAGACTGCATCCGAGCCTTCCGGGAAGAAGCCATTAAGTT
TTCAGAAGAGCAGCGCTTTAACAACTTCCTGAAAGCCCTTCAAGAGAAAGTGGAAATTAAACAATTAAATCATTTCTGGGAAATTGTTGT
CCAGGATGGAATTACTCTGATCACCAAAGAGGAAGCCTCTGGAAGTTCTGTCACAGCTGAGGAAGCCAAAAAGTTTCTGGCCCCCAAAGA
CAAACCAAGTGGAGACACAGCAGCTGTATTTGAAGAAGGTGGTGATGTGGACGATTTATTGGACATGATATAGGTCGTGGATGTATGGGG
AATCTAAGAGAGCTGCCATCGCTGTGATGCTGGGAGTTCTAACAAAACAAGTTGGATGCGGCCATTCAAGGGGAGCCAAAATCTCAAGAA
ATTCCCAGCAGGTTACCTGGAGGCGGATCATCTAATTCTCTGTGGAATGAATACACACATATATATTACAAGGGATAATTTAGACCCCAT
ACAAGTTTATAAAGAGTCATTGTTATTTTCTGGTTGGTGTATTATTTTTTCTGTGGTCTTACTGATCTTTGTATATTACATACATGCTTT
GAAGTTTCTGGAAAGTAGATCTTTTCTTGACCTAGTATATCAGTGACAGTTGCAGCCCTTGTGATGTGATTAGTGTCTCATGTGGAACCA
TGGCATGGTTATTGATGAGTTTCTTAACCCTTTCCAGAGTCCTCCTTTGCCTGATCCTCCAACAGCTGTCACAACTTGTGTTGAGCAAGC
AGTAGCATTTGCTTCCTCCCAACAAGCAGCTGGGTTAGGAAAACCATGGGTAAGGACGGACTCACTTCTCTTTTTAGTTGAGGCCTTCTA
GTTACCACATTACTCTGCCTCTGTATATAGGTGGTTTTCTTTAAGTGGGGTGGGAAGGGGAGCACAATTTCCCTTCATACTCCTTTTAAG
CAGTGAGTTATGGTGGTGGTCTCATGAAGAAAAGACCTTTTGGCCCAATCTCTGCCATATCAGTGAACCTTTAGAAACTCAAAAACTGAG
AAATTTACTACAGTAGTTAGAATTATATCACTTCACTGTTCTCTACTTGCAAGCCTCAAAGAGAGAAAGTTTCGTTATATTAAAACACTT
AGGTAACTTTTCGGTCTTTCCCATTTCTACCTAAGTCAGCTTTCATCTTTGTGGATGGTGTCTCCTTTACTAAATAAGAAAATAACAAAG
CCCTTATTCTCTTTTTTTCTTGTCCTCATTCTTGCCTTGAGTTCCAGTTCCTCTTTGGTGTACAGACTTCTTGGTACCCAGTCACCTCTG

>54887_54887_3_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000398656_XRCC5_chr2_217054948_ENST00000392132_length(amino acids)=501AA_BP=380
MTESSMKKLASTLLDAITDKDPLVQEQVCSALCSLGEARPVETLRACEEYLRQHDKLAHPYRAAVLRAMERVLSSRASELDKDTASTIIL
LASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDT
VRVAFCSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGI
LALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDT
SNERTRVGTLQVVRHVINSAASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQD

--------------------------------------------------------------
>54887_54887_4_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000398656_XRCC5_chr2_217054948_ENST00000392133_length(transcript)=2704nt_BP=1238nt
GGGAAGGCGGCGCCCCGGCCGAGGTGGCGGCGGCTCCTCAGATGGGAGAAGAAGTTGTCCATGTTCACACTGGGTGAAGGAAGCTGAAAC
CACAGACATGACTGAGTCCTCCATGAAGAAGCTGGCCTCCACCCTGCTGGACGCCATCACCGATAAGGACCCCCTGGTGCAGGAGCAGGT
CTGCAGTGCCCTGTGCTCCCTCGGGGAGGCGCGGCCGGTGGAGACGCTCCGTGCCTGCGAGGAGTATCTGCGGCAGCATGACAAGCTGGC
ACACCCATACCGAGCAGCGGTCCTGAGGGCCATGGAGAGGGTCCTGAGCAGTCGCGCCAGTGAGCTGGACAAGGACACAGCCAGCACCAT
CATCCTCCTGGCCTCCAGCGAGATGACCAAGACGAAGGACCTGGTCTGGGACTGGCAGCAGGCGGCGAGTGGCGTCCTGGTGGCCGTGGG
AAGACAGTTCATCAGCAAGGTGATGGAGGAGCTGCTGCGCAGGCTGCACCCTGGGACCCTGCCACACTGCGCCGTGCTGCACACCCTCGC
CAGCCTCTCGGTGGCCAACGCGTTCGGCGTAGTCCCCTTCCTGCCATCCGTCCTGAGCTCCCTGCTGCCCGTGCTGGGCGTGGCCAAGCA
GGACACGGTGCGCGTGGCCTTCTGCTCCGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTACCTAGCCAACCTGGACCGAGCCCCAGA
CCCCACGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCATCAGTGGCTGCAGAGTCGAGAAGCCAA
GCTCCGTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCTGGAAGAGCAGCTGCCCAAGCTCCTCCC
TGGGATTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCAGATCCTCGAGGCAGCTGTGAGTGTGGG
CAGCCGCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGTGCCTGTGGAGTCCTCAAGCCCCCTGGT
GATGAGTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCGCCTACTGGCCTTCCTGCTGCCCAGGCT
GGACACCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTCAGCTGCGAGTAACCAGCTCATAAATCA
CATCGAACAGTTTTTGGATACTAATGAAACACCGTATTTTATGAAGAGCATAGACTGCATCCGAGCCTTCCGGGAAGAAGCCATTAAGTT
TTCAGAAGAGCAGCGCTTTAACAACTTCCTGAAAGCCCTTCAAGAGAAAGTGGAAATTAAACAATTAAATCATTTCTGGGAAATTGTTGT
CCAGGATGGAATTACTCTGATCACCAAAGAGGAAGCCTCTGGAAGTTCTGTCACAGCTGAGGAAGCCAAAAAGTTTCTGGCCCCCAAAGA
CAAACCAAGTGGAGACACAGCAGCTGTATTTGAAGAAGGTGGTGATGTGGACGATTTATTGGACATGATATAGGTCGTGGATGTATGGGG
AATCTAAGAGAGCTGCCATCGCTGTGATGCTGGGAGTTCTAACAAAACAAGTTGGATGCGGCCATTCAAGGGGAGCCAAAATCTCAAGAA
ATTCCCAGCAGGTTACCTGGAGGCGGATCATCTAATTCTCTGTGGAATGAATACACACATATATATTACAAGGGATAATTTAGACCCCAT
ACAAGTTTATAAAGAGTCATTGTTATTTTCTGGTTGGTGTATTATTTTTTCTGTGGTCTTACTGATCTTTGTATATTACATACATGCTTT
GAAGTTTCTGGAAAGTAGATCTTTTCTTGACCTAGTATATCAGTGACAGTTGCAGCCCTTGTGATGTGATTAGTGTCTCATGTGGAACCA
TGGCATGGTTATTGATGAGTTTCTTAACCCTTTCCAGAGTCCTCCTTTGCCTGATCCTCCAACAGCTGTCACAACTTGTGTTGAGCAAGC
AGTAGCATTTGCTTCCTCCCAACAAGCAGCTGGGTTAGGAAAACCATGGGTAAGGACGGACTCACTTCTCTTTTTAGTTGAGGCCTTCTA
GTTACCACATTACTCTGCCTCTGTATATAGGTGGTTTTCTTTAAGTGGGGTGGGAAGGGGAGCACAATTTCCCTTCATACTCCTTTTAAG
CAGTGAGTTATGGTGGTGGTCTCATGAAGAAAAGACCTTTTGGCCCAATCTCTGCCATATCAGTGAACCTTTAGAAACTCAAAAACTGAG
AAATTTACTACAGTAGTTAGAATTATATCACTTCACTGTTCTCTACTTGCAAGCCTCAAAGAGAGAAAGTTTCGTTATATTAAAACACTT
AGGTAACTTTTCGGTCTTTCCCATTTCTACCTAAGTCAGCTTTCATCTTTGTGGATGGTGTCTCCTTTACTAAATAAGAAAATAACAAAG
CCCTTATTCTCTTTTTTTCTTGTCCTCATTCTTGCCTTGAGTTCCAGTTCCTCTTTGGTGTACAGACTTCTTGGTACCCAGTCACCTCTG
TCTTCAGCACCCTCATAAGTCGTCACTAATACACAGTTTTGTACATGTAACATTAAAGGCATAAATGACTCATCTCTCTGTGAATTGCTG

>54887_54887_4_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000398656_XRCC5_chr2_217054948_ENST00000392133_length(amino acids)=501AA_BP=380
MTESSMKKLASTLLDAITDKDPLVQEQVCSALCSLGEARPVETLRACEEYLRQHDKLAHPYRAAVLRAMERVLSSRASELDKDTASTIIL
LASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDT
VRVAFCSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGI
LALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDT
SNERTRVGTLQVVRHVINSAASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQD

--------------------------------------------------------------
>54887_54887_5_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000423230_XRCC5_chr2_217054948_ENST00000392132_length(transcript)=2692nt_BP=1238nt
GGGAAGGCGGCGCCCCGGCCGAGGTGGCGGCGGCTCCTCAGATGGGAGAAGAAGTTGTCCATGTTCACACTGGGTGAAGGAAGCTGAAAC
CACAGACATGACTGAGTCCTCCATGAAGAAGCTGGCCTCCACCCTGCTGGACGCCATCACCGATAAGGACCCCCTGGTGCAGGAGCAGGT
CTGCAGTGCCCTGTGCTCCCTCGGGGAGGCGCGGCCGGTGGAGACGCTCCGTGCCTGCGAGGAGTATCTGCGGCAGCATGACAAGCTGGC
ACACCCATACCGAGCAGCGGTCCTGAGGGCCATGGAGAGGGTCCTGAGCAGTCGCGCCAGTGAGCTGGACAAGGACACAGCCAGCACCAT
CATCCTCCTGGCCTCCAGCGAGATGACCAAGACGAAGGACCTGGTCTGGGACTGGCAGCAGGCGGCGAGTGGCGTCCTGGTGGCCGTGGG
AAGACAGTTCATCAGCAAGGTGATGGAGGAGCTGCTGCGCAGGCTGCACCCTGGGACCCTGCCACACTGCGCCGTGCTGCACACCCTCGC
CAGCCTCTCGGTGGCCAACGCGTTCGGCGTAGTCCCCTTCCTGCCATCCGTCCTGAGCTCCCTGCTGCCCGTGCTGGGCGTGGCCAAGCA
GGACACGGTGCGCGTGGCCTTCTGCTCCGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTACCTAGCCAACCTGGACCGAGCCCCAGA
CCCCACGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCATCAGTGGCTGCAGAGTCGAGAAGCCAA
GCTCCGTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCTGGAAGAGCAGCTGCCCAAGCTCCTCCC
TGGGATTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCAGATCCTCGAGGCAGCTGTGAGTGTGGG
CAGCCGCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGTGCCTGTGGAGTCCTCAAGCCCCCTGGT
GATGAGTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCGCCTACTGGCCTTCCTGCTGCCCAGGCT
GGACACCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTCAGCTGCGAGTAACCAGCTCATAAATCA
CATCGAACAGTTTTTGGATACTAATGAAACACCGTATTTTATGAAGAGCATAGACTGCATCCGAGCCTTCCGGGAAGAAGCCATTAAGTT
TTCAGAAGAGCAGCGCTTTAACAACTTCCTGAAAGCCCTTCAAGAGAAAGTGGAAATTAAACAATTAAATCATTTCTGGGAAATTGTTGT
CCAGGATGGAATTACTCTGATCACCAAAGAGGAAGCCTCTGGAAGTTCTGTCACAGCTGAGGAAGCCAAAAAGTTTCTGGCCCCCAAAGA
CAAACCAAGTGGAGACACAGCAGCTGTATTTGAAGAAGGTGGTGATGTGGACGATTTATTGGACATGATATAGGTCGTGGATGTATGGGG
AATCTAAGAGAGCTGCCATCGCTGTGATGCTGGGAGTTCTAACAAAACAAGTTGGATGCGGCCATTCAAGGGGAGCCAAAATCTCAAGAA
ATTCCCAGCAGGTTACCTGGAGGCGGATCATCTAATTCTCTGTGGAATGAATACACACATATATATTACAAGGGATAATTTAGACCCCAT
ACAAGTTTATAAAGAGTCATTGTTATTTTCTGGTTGGTGTATTATTTTTTCTGTGGTCTTACTGATCTTTGTATATTACATACATGCTTT
GAAGTTTCTGGAAAGTAGATCTTTTCTTGACCTAGTATATCAGTGACAGTTGCAGCCCTTGTGATGTGATTAGTGTCTCATGTGGAACCA
TGGCATGGTTATTGATGAGTTTCTTAACCCTTTCCAGAGTCCTCCTTTGCCTGATCCTCCAACAGCTGTCACAACTTGTGTTGAGCAAGC
AGTAGCATTTGCTTCCTCCCAACAAGCAGCTGGGTTAGGAAAACCATGGGTAAGGACGGACTCACTTCTCTTTTTAGTTGAGGCCTTCTA
GTTACCACATTACTCTGCCTCTGTATATAGGTGGTTTTCTTTAAGTGGGGTGGGAAGGGGAGCACAATTTCCCTTCATACTCCTTTTAAG
CAGTGAGTTATGGTGGTGGTCTCATGAAGAAAAGACCTTTTGGCCCAATCTCTGCCATATCAGTGAACCTTTAGAAACTCAAAAACTGAG
AAATTTACTACAGTAGTTAGAATTATATCACTTCACTGTTCTCTACTTGCAAGCCTCAAAGAGAGAAAGTTTCGTTATATTAAAACACTT
AGGTAACTTTTCGGTCTTTCCCATTTCTACCTAAGTCAGCTTTCATCTTTGTGGATGGTGTCTCCTTTACTAAATAAGAAAATAACAAAG
CCCTTATTCTCTTTTTTTCTTGTCCTCATTCTTGCCTTGAGTTCCAGTTCCTCTTTGGTGTACAGACTTCTTGGTACCCAGTCACCTCTG

>54887_54887_5_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000423230_XRCC5_chr2_217054948_ENST00000392132_length(amino acids)=501AA_BP=380
MTESSMKKLASTLLDAITDKDPLVQEQVCSALCSLGEARPVETLRACEEYLRQHDKLAHPYRAAVLRAMERVLSSRASELDKDTASTIIL
LASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDT
VRVAFCSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGI
LALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDT
SNERTRVGTLQVVRHVINSAASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQD

--------------------------------------------------------------
>54887_54887_6_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000423230_XRCC5_chr2_217054948_ENST00000392133_length(transcript)=2704nt_BP=1238nt
GGGAAGGCGGCGCCCCGGCCGAGGTGGCGGCGGCTCCTCAGATGGGAGAAGAAGTTGTCCATGTTCACACTGGGTGAAGGAAGCTGAAAC
CACAGACATGACTGAGTCCTCCATGAAGAAGCTGGCCTCCACCCTGCTGGACGCCATCACCGATAAGGACCCCCTGGTGCAGGAGCAGGT
CTGCAGTGCCCTGTGCTCCCTCGGGGAGGCGCGGCCGGTGGAGACGCTCCGTGCCTGCGAGGAGTATCTGCGGCAGCATGACAAGCTGGC
ACACCCATACCGAGCAGCGGTCCTGAGGGCCATGGAGAGGGTCCTGAGCAGTCGCGCCAGTGAGCTGGACAAGGACACAGCCAGCACCAT
CATCCTCCTGGCCTCCAGCGAGATGACCAAGACGAAGGACCTGGTCTGGGACTGGCAGCAGGCGGCGAGTGGCGTCCTGGTGGCCGTGGG
AAGACAGTTCATCAGCAAGGTGATGGAGGAGCTGCTGCGCAGGCTGCACCCTGGGACCCTGCCACACTGCGCCGTGCTGCACACCCTCGC
CAGCCTCTCGGTGGCCAACGCGTTCGGCGTAGTCCCCTTCCTGCCATCCGTCCTGAGCTCCCTGCTGCCCGTGCTGGGCGTGGCCAAGCA
GGACACGGTGCGCGTGGCCTTCTGCTCCGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTACCTAGCCAACCTGGACCGAGCCCCAGA
CCCCACGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCATCAGTGGCTGCAGAGTCGAGAAGCCAA
GCTCCGTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCTGGAAGAGCAGCTGCCCAAGCTCCTCCC
TGGGATTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCAGATCCTCGAGGCAGCTGTGAGTGTGGG
CAGCCGCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGTGCCTGTGGAGTCCTCAAGCCCCCTGGT
GATGAGTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCGCCTACTGGCCTTCCTGCTGCCCAGGCT
GGACACCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTCAGCTGCGAGTAACCAGCTCATAAATCA
CATCGAACAGTTTTTGGATACTAATGAAACACCGTATTTTATGAAGAGCATAGACTGCATCCGAGCCTTCCGGGAAGAAGCCATTAAGTT
TTCAGAAGAGCAGCGCTTTAACAACTTCCTGAAAGCCCTTCAAGAGAAAGTGGAAATTAAACAATTAAATCATTTCTGGGAAATTGTTGT
CCAGGATGGAATTACTCTGATCACCAAAGAGGAAGCCTCTGGAAGTTCTGTCACAGCTGAGGAAGCCAAAAAGTTTCTGGCCCCCAAAGA
CAAACCAAGTGGAGACACAGCAGCTGTATTTGAAGAAGGTGGTGATGTGGACGATTTATTGGACATGATATAGGTCGTGGATGTATGGGG
AATCTAAGAGAGCTGCCATCGCTGTGATGCTGGGAGTTCTAACAAAACAAGTTGGATGCGGCCATTCAAGGGGAGCCAAAATCTCAAGAA
ATTCCCAGCAGGTTACCTGGAGGCGGATCATCTAATTCTCTGTGGAATGAATACACACATATATATTACAAGGGATAATTTAGACCCCAT
ACAAGTTTATAAAGAGTCATTGTTATTTTCTGGTTGGTGTATTATTTTTTCTGTGGTCTTACTGATCTTTGTATATTACATACATGCTTT
GAAGTTTCTGGAAAGTAGATCTTTTCTTGACCTAGTATATCAGTGACAGTTGCAGCCCTTGTGATGTGATTAGTGTCTCATGTGGAACCA
TGGCATGGTTATTGATGAGTTTCTTAACCCTTTCCAGAGTCCTCCTTTGCCTGATCCTCCAACAGCTGTCACAACTTGTGTTGAGCAAGC
AGTAGCATTTGCTTCCTCCCAACAAGCAGCTGGGTTAGGAAAACCATGGGTAAGGACGGACTCACTTCTCTTTTTAGTTGAGGCCTTCTA
GTTACCACATTACTCTGCCTCTGTATATAGGTGGTTTTCTTTAAGTGGGGTGGGAAGGGGAGCACAATTTCCCTTCATACTCCTTTTAAG
CAGTGAGTTATGGTGGTGGTCTCATGAAGAAAAGACCTTTTGGCCCAATCTCTGCCATATCAGTGAACCTTTAGAAACTCAAAAACTGAG
AAATTTACTACAGTAGTTAGAATTATATCACTTCACTGTTCTCTACTTGCAAGCCTCAAAGAGAGAAAGTTTCGTTATATTAAAACACTT
AGGTAACTTTTCGGTCTTTCCCATTTCTACCTAAGTCAGCTTTCATCTTTGTGGATGGTGTCTCCTTTACTAAATAAGAAAATAACAAAG
CCCTTATTCTCTTTTTTTCTTGTCCTCATTCTTGCCTTGAGTTCCAGTTCCTCTTTGGTGTACAGACTTCTTGGTACCCAGTCACCTCTG
TCTTCAGCACCCTCATAAGTCGTCACTAATACACAGTTTTGTACATGTAACATTAAAGGCATAAATGACTCATCTCTCTGTGAATTGCTG

>54887_54887_6_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000423230_XRCC5_chr2_217054948_ENST00000392133_length(amino acids)=501AA_BP=380
MTESSMKKLASTLLDAITDKDPLVQEQVCSALCSLGEARPVETLRACEEYLRQHDKLAHPYRAAVLRAMERVLSSRASELDKDTASTIIL
LASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDT
VRVAFCSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGI
LALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDT
SNERTRVGTLQVVRHVINSAASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQD

--------------------------------------------------------------
>54887_54887_7_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000528919_XRCC5_chr2_217054948_ENST00000392132_length(transcript)=2716nt_BP=1262nt
CCAGGCCACCTGCATTCCTTGTCTCAGAGCCTCCCTCCTGCATCCTCCAAGCCAGCAGTTGTGGGATGGGAGAAGAAGTTGTCCATGTTC
ACACTGGGTGAAGGAAGCTGAAACCACAGACATGACTGAGTCCTCCATGAAGAAGCTGGCCTCCACCCTGCTGGACGCCATCACCGATAA
GGACCCCCTGGTGCAGGAGCAGGTCTGCAGTGCCCTGTGCTCCCTCGGGGAGGCGCGGCCGGTGGAGACGCTCCGTGCCTGCGAGGAGTA
TCTGCGGCAGCATGACAAGCTGGCACACCCATACCGAGCAGCGGTCCTGAGGGCCATGGAGAGGGTCCTGAGCAGTCGCGCCAGTGAGCT
GGACAAGGACACAGCCAGCACCATCATCCTCCTGGCCTCCAGCGAGATGACCAAGACGAAGGACCTGGTCTGGGACTGGCAGCAGGCGGC
GAGTGGCGTCCTGGTGGCCGTGGGAAGACAGTTCATCAGCAAGGTGATGGAGGAGCTGCTGCGCAGGCTGCACCCTGGGACCCTGCCACA
CTGCGCCGTGCTGCACACCCTCGCCAGCCTCTCGGTGGCCAACGCGTTCGGCGTAGTCCCCTTCCTGCCATCCGTCCTGAGCTCCCTGCT
GCCCGTGCTGGGCGTGGCCAAGCAGGACACGGTGCGCGTGGCCTTCTGCTCCGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTACCT
AGCCAACCTGGACCGAGCCCCAGACCCCACGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCATCA
GTGGCTGCAGAGTCGAGAAGCCAAGCTCCGTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCTGGA
AGAGCAGCTGCCCAAGCTCCTCCCTGGGATTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCAGAT
CCTCGAGGCAGCTGTGAGTGTGGGCAGCCGCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGTGCC
TGTGGAGTCCTCAAGCCCCCTGGTGATGAGTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCGCCT
ACTGGCCTTCCTGCTGCCCAGGCTGGACACCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTCAGC
TGCGAGTAACCAGCTCATAAATCACATCGAACAGTTTTTGGATACTAATGAAACACCGTATTTTATGAAGAGCATAGACTGCATCCGAGC
CTTCCGGGAAGAAGCCATTAAGTTTTCAGAAGAGCAGCGCTTTAACAACTTCCTGAAAGCCCTTCAAGAGAAAGTGGAAATTAAACAATT
AAATCATTTCTGGGAAATTGTTGTCCAGGATGGAATTACTCTGATCACCAAAGAGGAAGCCTCTGGAAGTTCTGTCACAGCTGAGGAAGC
CAAAAAGTTTCTGGCCCCCAAAGACAAACCAAGTGGAGACACAGCAGCTGTATTTGAAGAAGGTGGTGATGTGGACGATTTATTGGACAT
GATATAGGTCGTGGATGTATGGGGAATCTAAGAGAGCTGCCATCGCTGTGATGCTGGGAGTTCTAACAAAACAAGTTGGATGCGGCCATT
CAAGGGGAGCCAAAATCTCAAGAAATTCCCAGCAGGTTACCTGGAGGCGGATCATCTAATTCTCTGTGGAATGAATACACACATATATAT
TACAAGGGATAATTTAGACCCCATACAAGTTTATAAAGAGTCATTGTTATTTTCTGGTTGGTGTATTATTTTTTCTGTGGTCTTACTGAT
CTTTGTATATTACATACATGCTTTGAAGTTTCTGGAAAGTAGATCTTTTCTTGACCTAGTATATCAGTGACAGTTGCAGCCCTTGTGATG
TGATTAGTGTCTCATGTGGAACCATGGCATGGTTATTGATGAGTTTCTTAACCCTTTCCAGAGTCCTCCTTTGCCTGATCCTCCAACAGC
TGTCACAACTTGTGTTGAGCAAGCAGTAGCATTTGCTTCCTCCCAACAAGCAGCTGGGTTAGGAAAACCATGGGTAAGGACGGACTCACT
TCTCTTTTTAGTTGAGGCCTTCTAGTTACCACATTACTCTGCCTCTGTATATAGGTGGTTTTCTTTAAGTGGGGTGGGAAGGGGAGCACA
ATTTCCCTTCATACTCCTTTTAAGCAGTGAGTTATGGTGGTGGTCTCATGAAGAAAAGACCTTTTGGCCCAATCTCTGCCATATCAGTGA
ACCTTTAGAAACTCAAAAACTGAGAAATTTACTACAGTAGTTAGAATTATATCACTTCACTGTTCTCTACTTGCAAGCCTCAAAGAGAGA
AAGTTTCGTTATATTAAAACACTTAGGTAACTTTTCGGTCTTTCCCATTTCTACCTAAGTCAGCTTTCATCTTTGTGGATGGTGTCTCCT
TTACTAAATAAGAAAATAACAAAGCCCTTATTCTCTTTTTTTCTTGTCCTCATTCTTGCCTTGAGTTCCAGTTCCTCTTTGGTGTACAGA
CTTCTTGGTACCCAGTCACCTCTGTCTTCAGCACCCTCATAAGTCGTCACTAATACACAGTTTTGTACATGTAACATTAAAGGCATAAAT

>54887_54887_7_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000528919_XRCC5_chr2_217054948_ENST00000392132_length(amino acids)=529AA_BP=408
MHPPSQQLWDGRRSCPCSHWVKEAETTDMTESSMKKLASTLLDAITDKDPLVQEQVCSALCSLGEARPVETLRACEEYLRQHDKLAHPYR
AAVLRAMERVLSSRASELDKDTASTIILLASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLPHCAVLHTLASLSV
ANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLA
VVEALGPMSHLLPSERLEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSPLVMSNQ
KEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHVINSAASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQ

--------------------------------------------------------------
>54887_54887_8_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000528919_XRCC5_chr2_217054948_ENST00000392133_length(transcript)=2728nt_BP=1262nt
CCAGGCCACCTGCATTCCTTGTCTCAGAGCCTCCCTCCTGCATCCTCCAAGCCAGCAGTTGTGGGATGGGAGAAGAAGTTGTCCATGTTC
ACACTGGGTGAAGGAAGCTGAAACCACAGACATGACTGAGTCCTCCATGAAGAAGCTGGCCTCCACCCTGCTGGACGCCATCACCGATAA
GGACCCCCTGGTGCAGGAGCAGGTCTGCAGTGCCCTGTGCTCCCTCGGGGAGGCGCGGCCGGTGGAGACGCTCCGTGCCTGCGAGGAGTA
TCTGCGGCAGCATGACAAGCTGGCACACCCATACCGAGCAGCGGTCCTGAGGGCCATGGAGAGGGTCCTGAGCAGTCGCGCCAGTGAGCT
GGACAAGGACACAGCCAGCACCATCATCCTCCTGGCCTCCAGCGAGATGACCAAGACGAAGGACCTGGTCTGGGACTGGCAGCAGGCGGC
GAGTGGCGTCCTGGTGGCCGTGGGAAGACAGTTCATCAGCAAGGTGATGGAGGAGCTGCTGCGCAGGCTGCACCCTGGGACCCTGCCACA
CTGCGCCGTGCTGCACACCCTCGCCAGCCTCTCGGTGGCCAACGCGTTCGGCGTAGTCCCCTTCCTGCCATCCGTCCTGAGCTCCCTGCT
GCCCGTGCTGGGCGTGGCCAAGCAGGACACGGTGCGCGTGGCCTTCTGCTCCGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTACCT
AGCCAACCTGGACCGAGCCCCAGACCCCACGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCATCA
GTGGCTGCAGAGTCGAGAAGCCAAGCTCCGTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCTGGA
AGAGCAGCTGCCCAAGCTCCTCCCTGGGATTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCAGAT
CCTCGAGGCAGCTGTGAGTGTGGGCAGCCGCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGTGCC
TGTGGAGTCCTCAAGCCCCCTGGTGATGAGTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCGCCT
ACTGGCCTTCCTGCTGCCCAGGCTGGACACCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTCAGC
TGCGAGTAACCAGCTCATAAATCACATCGAACAGTTTTTGGATACTAATGAAACACCGTATTTTATGAAGAGCATAGACTGCATCCGAGC
CTTCCGGGAAGAAGCCATTAAGTTTTCAGAAGAGCAGCGCTTTAACAACTTCCTGAAAGCCCTTCAAGAGAAAGTGGAAATTAAACAATT
AAATCATTTCTGGGAAATTGTTGTCCAGGATGGAATTACTCTGATCACCAAAGAGGAAGCCTCTGGAAGTTCTGTCACAGCTGAGGAAGC
CAAAAAGTTTCTGGCCCCCAAAGACAAACCAAGTGGAGACACAGCAGCTGTATTTGAAGAAGGTGGTGATGTGGACGATTTATTGGACAT
GATATAGGTCGTGGATGTATGGGGAATCTAAGAGAGCTGCCATCGCTGTGATGCTGGGAGTTCTAACAAAACAAGTTGGATGCGGCCATT
CAAGGGGAGCCAAAATCTCAAGAAATTCCCAGCAGGTTACCTGGAGGCGGATCATCTAATTCTCTGTGGAATGAATACACACATATATAT
TACAAGGGATAATTTAGACCCCATACAAGTTTATAAAGAGTCATTGTTATTTTCTGGTTGGTGTATTATTTTTTCTGTGGTCTTACTGAT
CTTTGTATATTACATACATGCTTTGAAGTTTCTGGAAAGTAGATCTTTTCTTGACCTAGTATATCAGTGACAGTTGCAGCCCTTGTGATG
TGATTAGTGTCTCATGTGGAACCATGGCATGGTTATTGATGAGTTTCTTAACCCTTTCCAGAGTCCTCCTTTGCCTGATCCTCCAACAGC
TGTCACAACTTGTGTTGAGCAAGCAGTAGCATTTGCTTCCTCCCAACAAGCAGCTGGGTTAGGAAAACCATGGGTAAGGACGGACTCACT
TCTCTTTTTAGTTGAGGCCTTCTAGTTACCACATTACTCTGCCTCTGTATATAGGTGGTTTTCTTTAAGTGGGGTGGGAAGGGGAGCACA
ATTTCCCTTCATACTCCTTTTAAGCAGTGAGTTATGGTGGTGGTCTCATGAAGAAAAGACCTTTTGGCCCAATCTCTGCCATATCAGTGA
ACCTTTAGAAACTCAAAAACTGAGAAATTTACTACAGTAGTTAGAATTATATCACTTCACTGTTCTCTACTTGCAAGCCTCAAAGAGAGA
AAGTTTCGTTATATTAAAACACTTAGGTAACTTTTCGGTCTTTCCCATTTCTACCTAAGTCAGCTTTCATCTTTGTGGATGGTGTCTCCT
TTACTAAATAAGAAAATAACAAAGCCCTTATTCTCTTTTTTTCTTGTCCTCATTCTTGCCTTGAGTTCCAGTTCCTCTTTGGTGTACAGA
CTTCTTGGTACCCAGTCACCTCTGTCTTCAGCACCCTCATAAGTCGTCACTAATACACAGTTTTGTACATGTAACATTAAAGGCATAAAT

>54887_54887_8_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000528919_XRCC5_chr2_217054948_ENST00000392133_length(amino acids)=529AA_BP=408
MHPPSQQLWDGRRSCPCSHWVKEAETTDMTESSMKKLASTLLDAITDKDPLVQEQVCSALCSLGEARPVETLRACEEYLRQHDKLAHPYR
AAVLRAMERVLSSRASELDKDTASTIILLASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLPHCAVLHTLASLSV
ANAFGVVPFLPSVLSSLLPVLGVAKQDTVRVAFCSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLA
VVEALGPMSHLLPSERLEEQLPKLLPGILALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSPLVMSNQ
KEVLRCFTVLACSSPDRLLAFLLPRLDTSNERTRVGTLQVVRHVINSAASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQ

--------------------------------------------------------------
>54887_54887_9_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000534366_XRCC5_chr2_217054948_ENST00000392132_length(transcript)=2719nt_BP=1265nt
TGACTGGTCATAGCGTGCCGGGCATAGCGCTGGCAGGGCCGCCGGGAGCCAGCCCTCACTCAGCCAAGATGGGAGAAGAAGTTGTCCATG
TTCACACTGGGTGAAGGAAGCTGAAACCACAGACATGACTGAGTCCTCCATGAAGAAGCTGGCCTCCACCCTGCTGGACGCCATCACCGA
TAAGGACCCCCTGGTGCAGGAGCAGGTCTGCAGTGCCCTGTGCTCCCTCGGGGAGGCGCGGCCGGTGGAGACGCTCCGTGCCTGCGAGGA
GTATCTGCGGCAGCATGACAAGCTGGCACACCCATACCGAGCAGCGGTCCTGAGGGCCATGGAGAGGGTCCTGAGCAGTCGCGCCAGTGA
GCTGGACAAGGACACAGCCAGCACCATCATCCTCCTGGCCTCCAGCGAGATGACCAAGACGAAGGACCTGGTCTGGGACTGGCAGCAGGC
GGCGAGTGGCGTCCTGGTGGCCGTGGGAAGACAGTTCATCAGCAAGGTGATGGAGGAGCTGCTGCGCAGGCTGCACCCTGGGACCCTGCC
ACACTGCGCCGTGCTGCACACCCTCGCCAGCCTCTCGGTGGCCAACGCGTTCGGCGTAGTCCCCTTCCTGCCATCCGTCCTGAGCTCCCT
GCTGCCCGTGCTGGGCGTGGCCAAGCAGGACACGGTGCGCGTGGCCTTCTGCTCCGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTA
CCTAGCCAACCTGGACCGAGCCCCAGACCCCACGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCA
TCAGTGGCTGCAGAGTCGAGAAGCCAAGCTCCGTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCT
GGAAGAGCAGCTGCCCAAGCTCCTCCCTGGGATTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCA
GATCCTCGAGGCAGCTGTGAGTGTGGGCAGCCGCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGT
GCCTGTGGAGTCCTCAAGCCCCCTGGTGATGAGTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCG
CCTACTGGCCTTCCTGCTGCCCAGGCTGGACACCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTC
AGCTGCGAGTAACCAGCTCATAAATCACATCGAACAGTTTTTGGATACTAATGAAACACCGTATTTTATGAAGAGCATAGACTGCATCCG
AGCCTTCCGGGAAGAAGCCATTAAGTTTTCAGAAGAGCAGCGCTTTAACAACTTCCTGAAAGCCCTTCAAGAGAAAGTGGAAATTAAACA
ATTAAATCATTTCTGGGAAATTGTTGTCCAGGATGGAATTACTCTGATCACCAAAGAGGAAGCCTCTGGAAGTTCTGTCACAGCTGAGGA
AGCCAAAAAGTTTCTGGCCCCCAAAGACAAACCAAGTGGAGACACAGCAGCTGTATTTGAAGAAGGTGGTGATGTGGACGATTTATTGGA
CATGATATAGGTCGTGGATGTATGGGGAATCTAAGAGAGCTGCCATCGCTGTGATGCTGGGAGTTCTAACAAAACAAGTTGGATGCGGCC
ATTCAAGGGGAGCCAAAATCTCAAGAAATTCCCAGCAGGTTACCTGGAGGCGGATCATCTAATTCTCTGTGGAATGAATACACACATATA
TATTACAAGGGATAATTTAGACCCCATACAAGTTTATAAAGAGTCATTGTTATTTTCTGGTTGGTGTATTATTTTTTCTGTGGTCTTACT
GATCTTTGTATATTACATACATGCTTTGAAGTTTCTGGAAAGTAGATCTTTTCTTGACCTAGTATATCAGTGACAGTTGCAGCCCTTGTG
ATGTGATTAGTGTCTCATGTGGAACCATGGCATGGTTATTGATGAGTTTCTTAACCCTTTCCAGAGTCCTCCTTTGCCTGATCCTCCAAC
AGCTGTCACAACTTGTGTTGAGCAAGCAGTAGCATTTGCTTCCTCCCAACAAGCAGCTGGGTTAGGAAAACCATGGGTAAGGACGGACTC
ACTTCTCTTTTTAGTTGAGGCCTTCTAGTTACCACATTACTCTGCCTCTGTATATAGGTGGTTTTCTTTAAGTGGGGTGGGAAGGGGAGC
ACAATTTCCCTTCATACTCCTTTTAAGCAGTGAGTTATGGTGGTGGTCTCATGAAGAAAAGACCTTTTGGCCCAATCTCTGCCATATCAG
TGAACCTTTAGAAACTCAAAAACTGAGAAATTTACTACAGTAGTTAGAATTATATCACTTCACTGTTCTCTACTTGCAAGCCTCAAAGAG
AGAAAGTTTCGTTATATTAAAACACTTAGGTAACTTTTCGGTCTTTCCCATTTCTACCTAAGTCAGCTTTCATCTTTGTGGATGGTGTCT
CCTTTACTAAATAAGAAAATAACAAAGCCCTTATTCTCTTTTTTTCTTGTCCTCATTCTTGCCTTGAGTTCCAGTTCCTCTTTGGTGTAC
AGACTTCTTGGTACCCAGTCACCTCTGTCTTCAGCACCCTCATAAGTCGTCACTAATACACAGTTTTGTACATGTAACATTAAAGGCATA

>54887_54887_9_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000534366_XRCC5_chr2_217054948_ENST00000392132_length(amino acids)=501AA_BP=380
MTESSMKKLASTLLDAITDKDPLVQEQVCSALCSLGEARPVETLRACEEYLRQHDKLAHPYRAAVLRAMERVLSSRASELDKDTASTIIL
LASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDT
VRVAFCSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGI
LALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDT
SNERTRVGTLQVVRHVINSAASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQD

--------------------------------------------------------------
>54887_54887_10_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000534366_XRCC5_chr2_217054948_ENST00000392133_length(transcript)=2731nt_BP=1265nt
TGACTGGTCATAGCGTGCCGGGCATAGCGCTGGCAGGGCCGCCGGGAGCCAGCCCTCACTCAGCCAAGATGGGAGAAGAAGTTGTCCATG
TTCACACTGGGTGAAGGAAGCTGAAACCACAGACATGACTGAGTCCTCCATGAAGAAGCTGGCCTCCACCCTGCTGGACGCCATCACCGA
TAAGGACCCCCTGGTGCAGGAGCAGGTCTGCAGTGCCCTGTGCTCCCTCGGGGAGGCGCGGCCGGTGGAGACGCTCCGTGCCTGCGAGGA
GTATCTGCGGCAGCATGACAAGCTGGCACACCCATACCGAGCAGCGGTCCTGAGGGCCATGGAGAGGGTCCTGAGCAGTCGCGCCAGTGA
GCTGGACAAGGACACAGCCAGCACCATCATCCTCCTGGCCTCCAGCGAGATGACCAAGACGAAGGACCTGGTCTGGGACTGGCAGCAGGC
GGCGAGTGGCGTCCTGGTGGCCGTGGGAAGACAGTTCATCAGCAAGGTGATGGAGGAGCTGCTGCGCAGGCTGCACCCTGGGACCCTGCC
ACACTGCGCCGTGCTGCACACCCTCGCCAGCCTCTCGGTGGCCAACGCGTTCGGCGTAGTCCCCTTCCTGCCATCCGTCCTGAGCTCCCT
GCTGCCCGTGCTGGGCGTGGCCAAGCAGGACACGGTGCGCGTGGCCTTCTGCTCCGCTCTGCAGCGCTTCAGCGAGGGTGCCCTGGAGTA
CCTAGCCAACCTGGACCGAGCCCCAGACCCCACGGTCAGGAAGGACGCCTTTGCCACCGACATCTTCAGCGCCTACGATGTTCTCTTCCA
TCAGTGGCTGCAGAGTCGAGAAGCCAAGCTCCGTCTTGCCGTGGTGGAGGCTCTGGGGCCTATGAGCCATCTGCTGCCCAGTGAGAGGCT
GGAAGAGCAGCTGCCCAAGCTCCTCCCTGGGATTCTCGCCCTCTACAAGAAGCACGCAGAGACCTTCTACTTGTCCAAGAGCCTGGGCCA
GATCCTCGAGGCAGCTGTGAGTGTGGGCAGCCGCACACTGGAGACCCAGCTGGATGCCCTCTTGGCTGCACTGCACTCCCAGATCTGTGT
GCCTGTGGAGTCCTCAAGCCCCCTGGTGATGAGTAACCAGAAGGAGGTGCTGCGCTGCTTCACTGTGCTGGCCTGCAGCTCGCCTGACCG
CCTACTGGCCTTCCTGCTGCCCAGGCTGGACACCAGCAATGAGAGGACCCGCGTGGGCACCCTGCAGGTGGTCAGACATGTCATCAACTC
AGCTGCGAGTAACCAGCTCATAAATCACATCGAACAGTTTTTGGATACTAATGAAACACCGTATTTTATGAAGAGCATAGACTGCATCCG
AGCCTTCCGGGAAGAAGCCATTAAGTTTTCAGAAGAGCAGCGCTTTAACAACTTCCTGAAAGCCCTTCAAGAGAAAGTGGAAATTAAACA
ATTAAATCATTTCTGGGAAATTGTTGTCCAGGATGGAATTACTCTGATCACCAAAGAGGAAGCCTCTGGAAGTTCTGTCACAGCTGAGGA
AGCCAAAAAGTTTCTGGCCCCCAAAGACAAACCAAGTGGAGACACAGCAGCTGTATTTGAAGAAGGTGGTGATGTGGACGATTTATTGGA
CATGATATAGGTCGTGGATGTATGGGGAATCTAAGAGAGCTGCCATCGCTGTGATGCTGGGAGTTCTAACAAAACAAGTTGGATGCGGCC
ATTCAAGGGGAGCCAAAATCTCAAGAAATTCCCAGCAGGTTACCTGGAGGCGGATCATCTAATTCTCTGTGGAATGAATACACACATATA
TATTACAAGGGATAATTTAGACCCCATACAAGTTTATAAAGAGTCATTGTTATTTTCTGGTTGGTGTATTATTTTTTCTGTGGTCTTACT
GATCTTTGTATATTACATACATGCTTTGAAGTTTCTGGAAAGTAGATCTTTTCTTGACCTAGTATATCAGTGACAGTTGCAGCCCTTGTG
ATGTGATTAGTGTCTCATGTGGAACCATGGCATGGTTATTGATGAGTTTCTTAACCCTTTCCAGAGTCCTCCTTTGCCTGATCCTCCAAC
AGCTGTCACAACTTGTGTTGAGCAAGCAGTAGCATTTGCTTCCTCCCAACAAGCAGCTGGGTTAGGAAAACCATGGGTAAGGACGGACTC
ACTTCTCTTTTTAGTTGAGGCCTTCTAGTTACCACATTACTCTGCCTCTGTATATAGGTGGTTTTCTTTAAGTGGGGTGGGAAGGGGAGC
ACAATTTCCCTTCATACTCCTTTTAAGCAGTGAGTTATGGTGGTGGTCTCATGAAGAAAAGACCTTTTGGCCCAATCTCTGCCATATCAG
TGAACCTTTAGAAACTCAAAAACTGAGAAATTTACTACAGTAGTTAGAATTATATCACTTCACTGTTCTCTACTTGCAAGCCTCAAAGAG
AGAAAGTTTCGTTATATTAAAACACTTAGGTAACTTTTCGGTCTTTCCCATTTCTACCTAAGTCAGCTTTCATCTTTGTGGATGGTGTCT
CCTTTACTAAATAAGAAAATAACAAAGCCCTTATTCTCTTTTTTTCTTGTCCTCATTCTTGCCTTGAGTTCCAGTTCCTCTTTGGTGTAC
AGACTTCTTGGTACCCAGTCACCTCTGTCTTCAGCACCCTCATAAGTCGTCACTAATACACAGTTTTGTACATGTAACATTAAAGGCATA

>54887_54887_10_MROH1-XRCC5_MROH1_chr8_145255444_ENST00000534366_XRCC5_chr2_217054948_ENST00000392133_length(amino acids)=501AA_BP=380
MTESSMKKLASTLLDAITDKDPLVQEQVCSALCSLGEARPVETLRACEEYLRQHDKLAHPYRAAVLRAMERVLSSRASELDKDTASTIIL
LASSEMTKTKDLVWDWQQAASGVLVAVGRQFISKVMEELLRRLHPGTLPHCAVLHTLASLSVANAFGVVPFLPSVLSSLLPVLGVAKQDT
VRVAFCSALQRFSEGALEYLANLDRAPDPTVRKDAFATDIFSAYDVLFHQWLQSREAKLRLAVVEALGPMSHLLPSERLEEQLPKLLPGI
LALYKKHAETFYLSKSLGQILEAAVSVGSRTLETQLDALLAALHSQICVPVESSSPLVMSNQKEVLRCFTVLACSSPDRLLAFLLPRLDT
SNERTRVGTLQVVRHVINSAASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQD

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for MROH1-XRCC5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for MROH1-XRCC5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for MROH1-XRCC5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource