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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:MRPL11-ST8SIA1 (FusionGDB2 ID:54911) |
Fusion Gene Summary for MRPL11-ST8SIA1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MRPL11-ST8SIA1 | Fusion gene ID: 54911 | Hgene | Tgene | Gene symbol | MRPL11 | ST8SIA1 | Gene ID | 65003 | 6489 |
| Gene name | mitochondrial ribosomal protein L11 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | |
| Synonyms | CGI-113|L11MT|MRP-L11 | GD3S|SIAT8|SIAT8-A|SIAT8A|ST8SiaI | |
| Cytomap | 11q13.2 | 12p12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 39S ribosomal protein L11, mitochondrialmitochondrial large ribosomal subunit protein uL11m | alpha-N-acetylneuraminide alpha-2,8-sialyltransferaseST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 1alpha-2,8-sialyltransferase 8Adisialoganglioside (GD3) synthaseganglioside GD3 synthaseganglioside GT3 synthaseganglioside-specific alpha | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q9Y3B7 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000310999, ENST00000329819, ENST00000430466, ENST00000524576, | ENST00000381424, ENST00000404299, ENST00000536558, ENST00000396037, ENST00000539510, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 14 X 11 X 9=1386 |
| # samples | 3 | 15 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(15/1386*10)=-3.20789285164133 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MRPL11 [Title/Abstract] AND ST8SIA1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | MRPL11(66204575)-ST8SIA1(22402032), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across MRPL11 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across ST8SIA1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-B6-A0I2-01A | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
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Fusion Gene ORF analysis for MRPL11-ST8SIA1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000310999 | ENST00000381424 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5CDS-intron | ENST00000310999 | ENST00000404299 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5CDS-intron | ENST00000310999 | ENST00000536558 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5CDS-intron | ENST00000329819 | ENST00000381424 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5CDS-intron | ENST00000329819 | ENST00000404299 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5CDS-intron | ENST00000329819 | ENST00000536558 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5CDS-intron | ENST00000430466 | ENST00000381424 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5CDS-intron | ENST00000430466 | ENST00000404299 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5CDS-intron | ENST00000430466 | ENST00000536558 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5UTR-3CDS | ENST00000524576 | ENST00000396037 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5UTR-3CDS | ENST00000524576 | ENST00000539510 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5UTR-intron | ENST00000524576 | ENST00000381424 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5UTR-intron | ENST00000524576 | ENST00000404299 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| 5UTR-intron | ENST00000524576 | ENST00000536558 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| Frame-shift | ENST00000329819 | ENST00000396037 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| Frame-shift | ENST00000329819 | ENST00000539510 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| In-frame | ENST00000310999 | ENST00000396037 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| In-frame | ENST00000310999 | ENST00000539510 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| In-frame | ENST00000430466 | ENST00000396037 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| In-frame | ENST00000430466 | ENST00000539510 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000310999 | MRPL11 | chr11 | 66204575 | - | ENST00000396037 | ST8SIA1 | chr12 | 22402032 | - | 9308 | 567 | 94 | 1146 | 350 |
| ENST00000310999 | MRPL11 | chr11 | 66204575 | - | ENST00000539510 | ST8SIA1 | chr12 | 22402032 | - | 1557 | 567 | 94 | 1146 | 350 |
| ENST00000430466 | MRPL11 | chr11 | 66204575 | - | ENST00000396037 | ST8SIA1 | chr12 | 22402032 | - | 9230 | 489 | 94 | 1068 | 324 |
| ENST00000430466 | MRPL11 | chr11 | 66204575 | - | ENST00000539510 | ST8SIA1 | chr12 | 22402032 | - | 1479 | 489 | 94 | 1068 | 324 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000310999 | ENST00000396037 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - | 0.000161474 | 0.9998385 |
| ENST00000310999 | ENST00000539510 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - | 0.000968889 | 0.99903107 |
| ENST00000430466 | ENST00000396037 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - | 0.000148613 | 0.99985135 |
| ENST00000430466 | ENST00000539510 | MRPL11 | chr11 | 66204575 | - | ST8SIA1 | chr12 | 22402032 | - | 0.000955147 | 0.99904484 |
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Fusion Genomic Features for MRPL11-ST8SIA1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for MRPL11-ST8SIA1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:66204575/chr12:22402032) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MRPL11 | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | ST8SIA1 | chr11:66204575 | chr12:22402032 | ENST00000396037 | 2 | 5 | 188_190 | 163 | 357.0 | Region | Substrate binding | |
| Tgene | ST8SIA1 | chr11:66204575 | chr12:22402032 | ENST00000396037 | 2 | 5 | 274_276 | 163 | 357.0 | Region | Substrate binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | ST8SIA1 | chr11:66204575 | chr12:22402032 | ENST00000396037 | 2 | 5 | 1_29 | 163 | 357.0 | Topological domain | Cytoplasmic | |
| Tgene | ST8SIA1 | chr11:66204575 | chr12:22402032 | ENST00000396037 | 2 | 5 | 49_356 | 163 | 357.0 | Topological domain | Lumenal | |
| Tgene | ST8SIA1 | chr11:66204575 | chr12:22402032 | ENST00000396037 | 2 | 5 | 30_48 | 163 | 357.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
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Fusion Gene Sequence for MRPL11-ST8SIA1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >54911_54911_1_MRPL11-ST8SIA1_MRPL11_chr11_66204575_ENST00000310999_ST8SIA1_chr12_22402032_ENST00000396037_length(transcript)=9308nt_BP=567nt GTGAGGACCCTTGACCTCTGGCCCAAGATGGTGGCGCCCAGAGCTTCGCTCTTGCTGCTCCCCTGAGGTGAACTGAAGCCAGCAGCCCCG CATCATGTCAAAGCTCGGCCGGGCCGCCCGGGGCCTCAGGAAGCCCGAGGTCGGCGGTGTGATCCGGGCGATCGTGCGGGCAGGCCTGGC CATGCCCGGGCCCCCACTAGGCCCAGTGCTGGGTCAGAGAGGCGTTTCCATCAACCAGTTTTGCAAGGAGTTCAATGAGAGGACAAAGGA CATCAAGGAAGGCATTCCTCTGCCTACCAAGATTTTAGTGAAGCCTGACAGGACATTTGAAATTAAGATTGGACAGCCCACTGTTTCCTA CTTCCTGAAGGCAGCAGCTGGGATTGAAAAGGGGGCCCGGCAAACAGGGAAAGAGGTGGCAGGCCTGGTGACCTTGAAGCATGTGTATGA GATTGCCCGCATCAAAGCTCAGGATGAGGCATTTGCCCTGCAGGATGTACCCCTGTCGTCTGTTGTCCGCTCCATCATCGGGTCTGCCCG TTCTCTGGGCATTCGCGTGGTGAAGGAATGCAATCTCCCTCCTTTGTCAAGTGAATACACTAAGGATGTTGGATCCAAAAGTCAGTTAGT GACAGCTAATCCCAGCATAATTCGGCAAAGGTTTCAGAACCTTCTGTGGTCCAGAAAGACATTTGTGGACAACATGAAAATTTATAACCA CAGTTACATCTACATGCCTGCCTTTTCTATGAAGACAGGAACAGAGCCATCTTTGAGGGTTTATTATACACTGTCAGATGTTGGTGCCAA TCAAACAGTGCTGTTTGCCAACCCCAACTTTCTGCGTAGCATTGGAAAGTTCTGGAAAAGTAGAGGAATCCATGCCAAGCGCCTGTCCAC AGGACTTTTTCTGGTGAGCGCAGCTCTGGGTCTCTGTGAAGAGGTGGCCATCTATGGCTTCTGGCCCTTCTCTGTGAATATGCATGAGCA GCCCATCAGCCACCACTACTATGACAACGTCTTACCCTTTTCTGGCTTCCATGCCATGCCCGAGGAATTTCTCCAACTCTGGTATCTTCA TAAAATCGGTGCACTGAGAATGCAGCTGGACCCATGTGAAGATACCTCACTCCAGCCCACTTCCTAGGAACAATGGAAGAAGAAAGGACT GAACCAGGGTATTTTTGTTAGGTTTTCTATGTGACTCCAAGAGGGAATGGTCAAGTTGTTTCATGAGTTTGCATGGGCCCTTGGAAAAAC AGGAAAGGAGCAATGAAGATCCAAGCAAAACTTTACTTTCAGCGTTGGCTTGGAGGACAAATAAGAAATGAAACATCCTATGAAATACTT TATAGCACATGGCAGATTTGCAACTAGTAAAATGCTGGTGAAATGCTGTTGGTAAAGCACATGGTTCAAATCTAGAAGATGCAGTTCAAA AACAAGACAGACTCGAGTTGTTAGGGCTGAGGAACCAATCAAGGTAGAACAAAGAAAATGTTGGGGTAAAAGTGTTGCTGATTGTCAACA CAAACTGGCTTAATAATATTAATAAGAACCTGTCTTATTAAGACTGGCTTTAGAACCGTAGGTTTTTTTAAAAAATTATTATTTATTTTT GCCCTCTTTGGGGAAGTGGGTGGGTAGATTTAAAAAATCCCTTCCTGAGTAATAAAGATACAAAATGTTACTGCTGATAATTGTGATTTG TTGAGCCACGTCTATATTAACTATAGCTCCCCTCTATTTTTAAAATTTTACATAAGAATTGCTTCTTCCTCTTTTGTCAAGTCCACAGAG ACAATGTGAAGCATTATTGAATTTAGACTGTGTTGCTTCATAGTCTGGATAACAGGAGCCACTTTCCTTCCTCAGAATTTAGGACATAAA CCCAATTTTAGGTCTGCATTATGTAAGCCTGTTTGCATTGTCATTTTTATTTTAGTGCAAAAGACTACCAATATGAGTGAATTATTTGTT TGTAAATTGGCATAATTGTCTTCATAATTTAATGTTCAGAAATGCAGTAAAGCACGTTGATGAAAAGCTTAGTCTCTGTGGAAGACAGAC CAGAAGACAAATCCCTTTTCTATCTACTGTGGCATATTCACTGCAAGGTAAAGGACATGTATGCATACATGCAAGAATGAATTGAGCGAA ACTTTGAATATGTTTCCTCTTTTGAGCTATTGTTATTTAGTAGTTACCTAAAAAAGAATACATTTTTACTAGTATACCATTAAAAATGTA AAAGGCTTAACATGTATGCATACATGTAGACACACATACACACACACAAAGTTAAACAAAGCTCATTACTGTGCAACTATGAAAGCTGAA CTCATATGACCTGGTATGGCAAAAATTTGTAACCAGTGTTGGAGAATCACAAATGTGTTATGCACTATCCATTACATGTTGATATAAGAC AACCGAGCTCACTGGTTGCCGCACATAATACCCATAGCAGCACAAGATGCAAGTCTTACCCCCAAATGCTTACCCGGAATGAGCAGAATT GTCTTACTCATCCTGATTTTACCCAAAATCTCATGAATGGGCTTGCTGTTGAGCGTGGTCACACAAGGTATAGTTTGTACAAGTAAAGAA ATGTGAATTAGTAGCTATTTATTTCCTTAGTAGCAGGTAGGACTACTTAGCTTGTTACAACAGCTTTGATACACAGTAAGAAAACTCTAC TGACAGATTACAAGCAGCCAAATGTGTTTACATTTCAGAGAAGGGTAAGGGAAGCCTCTCGTTGTCTTCATACTTTGGAATGTCTTAAGC TAAAATGTGACACTAGAGTTCAATTTCTTTTTTATTTTAAATGTCACTAAATTGTAGGTAAACTGTACCAAAAAGTTCTAGTTTAATTTT AACAGTAAAAACTCAGCATACCATGTTACCACGTAAACAATAATGGCTGGTATTTTCTGTGGGTTAATTTAACATGACATAAACATAGGA AAGCCCTTGGCAAAATTCTACATCATTGAAGTAGACCATTTCTAAATGCAATTAAATAGTGAGGTTATTATAAAAATTAGAATTTAAAAT ATGACTTGTTGATAGTGCAGATTATAATGTTACTTAGAAAGTTAAGAATTCGAGAGTAATGATGCTATTGGAGAACTGGTTTGCTATACG GCAGCAAAAACATAATGAGAATGTACCATGAAGAAATTGTGTTAAATATTCACTTTGAGTGAAACTTTAAATATGTTTCCTCTTTTGAGC TACTGTTATTTAGCAGTTACCTAAAAAAGAATACATTTTTACTAGTCTACCATTAAAAATATAAAAGGCTTAACAAAAACGCATATAAAA GTTAATAAAATGTTACTCAGATTAGTACTTTAATTGTTAAAATGTAATTAATGAGCTCCATAGAGCCCATACATCACAGTTCCATTGAAA ATATCATCTGGACTAGAATCTCTTAAACCCAGGAAGTGGAGGTTGCAGTGAGCCAAGATGGTGCCACTGCACTCCAGCCTGGGTGACAGG GCAAGACCCTGTCTCAAAAAAAAAAAAAAGAAAAGAAAAAGAAAGAAAATATTATGTGGAAATTTTTCATCTTTTTATGATGCCTGGGAT AGATTTATGCAGTAGATTTATATATAATGTTTAGTTTACAAACTTGTGAAACTATTTCATGTGGGTTCTGAAAGGCAAAACAGAAATGGC CAGTGCTGGTGATGTTTGATTAGACCAGCTCTTCTCAGCTGGGGTGATTCATTATCCCTCTCTGGTGACATTTGGCAATGTCTGGAGACC AGAGACATTTTTTATTTTCATGACTCAAGGGTGCTAATAGCATGTACTTAGTAGAGGTTAGGGATCCTGCTAAAGATCTTACAATGCACA AGTCAGCCTCTCACAGCAAAATAATTATCCAGGCTGAGATGTCAGTAGTATCAAGGTTGACATCTCAGACCTGGATTAGACCTGGATTAG ACCAAAATGAAATTTTGATTGTTCCACCTTGTCTTCACTTAAAGATAGATATACATGCTCACAGCATTCAAAATATGACTACAATTTAAT GAAAATATTTTCTTATGGTAGATTACAACTCACTAGATACACCATACATATGCCTTTTGGACATAATTGGTTAGATAGGAGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGCATGAAGTTAGGCATCTCTATCCTTAACTGTGCTATGTGTTCCTAAGTAAGG ACCTCGCTAGAATCATCCTGTAGAGTGCTCTGGAATACTCTATTATTAAGATCTTCAATTCTAAGCTCCCATTATCTTTCTTTGTTTATC TGAAATTAAGACCTTCAGAATTAGGCCTGGTACTTTTCCAGATTTGATCAGTTACATTTTGATATAACTGACTCTTAAAATTCAGCTTAG AAGACATTCAATAAGAAAATCTTTAATCACTTTTGGTGATGCACCTGCCAAGAGGGGGCATCACTTTGTACCATCAGACTAATTAAAAAA ATTGTTGTGTAGTCATAAAAATTAGGCTGATCCATAGGGGCAAAAGGAAGGGTGAAGAGACTAAAAACTAGTACCCTGATAGAATTTTAG TTTTTATTAGCCTCGATTTGAGAACTGCATTGATTCCAAAGATCATGAAGGTAGGTGAAGGATTAAGTCATTCCATAATTAAGAAAAGTA ATGTTTATATGAAAGATTTTTATATGGACAATGACTCACAGACACATATGCTTTGTATAGAGGATTTTGCCAAAAGTTTATACAAAATTG CACATCTAAACTGCATAATTCTCATACAAGAAGTTAAGGAAGTGCTCACTGGATTTTGCTTCTGTATAGTTCACTTTTATCTGTCTTCAC AAGGGTAGGAAGTAAATGATCTCAAATGGCACATGTTCAGACAATACTGTGTTTGGCTTTGTGATGTCTCATGTCTTTCTCTTGGCTAAA AAAAATTGTTTAGGCTATATATAACTTGTACCTGAAGCAATCTGGACAACATGGCTTAAAATGGAAAATAACTGAAAAAATCCTGGGATT TTAAATTTGCCAAAAATACCCTTGGATTAGTCAAAGGCTTTACAAGAGTGTTATAGATGATCCAAAATGGAAACAATATTGATAACATTT CTTTTCGTCAGCAGCTACATATTCCAGTTTTATAACTTTATTATATACATTTTTTGATTATTAATAGAAAGTCAGCCATCCAGAGTTTTA ACTTCTGTGGTTGAAATATTGACTTTGTGAAATTTTTCACTGACAAATACTTGTTAGGAGGGACCTAAGGGGGAGGGGAATGTTACCAGT CCACTGAAAACTTTAGGAAATGTTCATTGTGTTGTGTAAATACTTTCCCACCAGCACCAGGTAATATATTCTCTATGTTTGTAGAATTCC AAAGATCAAAAGCTGTAAGGACGTTTATGTGAACTTGACGCAAACTTGTGGAGGAATAAGGACTGAGAGTAATGTTGTGCTTTTTCTTTA TCTTCCCGTCGTATAGGTCGACTCTCAGGTTATATGACTTTTATTGGGCACACGTCAGGGGTGGAAGTGGTAGAAGTGGGTTAACAATTT CAAGGCCTGGCAACCTAGGTCAAAACCTCTAATAAAGTCAGCAGTAAACATAACTAGCAACTTCATTCCACTATGTGCTAGGAGGAGGGT GAGGCAAGTTGAAAGGAGATGACCCTATCCCCACACTCTCAGGATGTAAAAGGGCAGAGTGCTCTCTACCCTTAACCTTGGCTTTTTAGC ACCGTCAGTCTCTGTCCTCTCCCAGGAGAGCTGCCTTGGCTCCAGAGTTGAGCTAGTAGCATTGTGACTAGAGAGGTAGTGTGGAAATTC GCTGAGGACCTCAAAATTTTACACTGCCTTAAACTGTTTTGTTTTTGCTTAAACTCGTGCTGTCTAAATGTGGGTGTTTTGTGGCAGAGT CTGATCACCCCGACCTAGTTATAGCCCTGCCAGTGATTCTAAAGTGGAACTTTTCCCCCTCATTCATATGGATAGTCTGAGTCCTTGAAG CTAGGGAGATATCAAATATTCTACCAGTTCCTACATAGCTTCTTTAAAAGTCCTAGAGACTAACTCACAGGAAGTCTGAAGCCCAGAGCG TCTGTTTATAAACTCCTAAATATGAGGCCACAATATTTAGGTTGAGCACTAGAAAATTTCTATTTTGCAAGTGGAAGGAGACTTGAATCT ATAATTGCTGTAGCTTTTTTTCCCTTCTATCATAAGAAAATGGATACCATCTGCTTTACCCTCAGCCCAGACTTGTCTTTTGAATTTTTT ACATACATCTTAGGGGTGAGAGATTGAAACAAGTGCATGAATGAAAAGCTTATTGAAACATAACACAGCCCCTGCTCACCATTTCAGTAA GGGAAAATACATGTTTCTGTTTCCCTCTAATTTGTTTTCTCTGGTGCCAACATTTCTGATTTCTTCTGTCTCTAATACATAAGGAATAAA TACCATATTTTAAATTGACTTACATGCCTGCGAGCATTTGCCAGATAATCAAAGCCTATGACTCTAACTTTTTAAAGCACAGAAGAGGAA TTATATTTTATGGTCACTCCTCTGTGTTTCTATTGATCTCTATATTGTGCTAAAATTCTTTCAGGTAATTTTTTTCTTGTTGAAGCTGTG GGATATAATCAATGATGCCAAGCTGTCTGAGAATTTTATAGAATAATATCCAAATATATTGATCCTGCCTCTTTCTGCTTCTATGTAATT AAACTTTCTTTTGATGTTTATTTTTAAAATGTATGCTTCACACAACACCAATAAACATCTAAGAGATGTGATATAATCCAAGGCAAAGAA AAGTAAGAATCAGTTAATGTCTATTTTATCTGCACAGCATTACGAACAGAAAATTGTAATAAAAAAAGGTTTAACCAAACTGAAAAAAAG AGAGACAAAATCTTGGTTTTAATTTGAAAAGATGATTGGGAGTGATCTCAGAAGAGAGTTCAGCAGGAAGCAAGGAAGAGGCTGTTGACC TTGAGTGCAGCCTCAAGAATGGAACCTTTTTGAAATATTTTAAAGGAAATATCTTGTCATCCAGCTGTTATGGTTAATAATGAATAGTTT TCTCTGGGTGAAGCTTATCCATTGCACACCTGATGTGCTGGCCCCTGCGATTTCCCCAAATGTTGGAATGTTGCCTGCATAATTTGTGGT AATGGGGGACTGTGTTCCTGCTTTTACCTGGTTACAAAAAACAAAACAAAACAAAACAAAACAACAAACAGAAAAAAAAAGAGAGAAAAG ATGCTAGAGGAAGCAGTGTGACAGACAGATCATGAGATGCTGACGGAGAGAACAGAGTGGTACCTGTTTACCCACTTGGACCATGACAGT ATCAAGGCTCCACCCCTTGCTGTCCCTTCCCAAGAGGTGCTCTCCTGGGAGTTTGATCACAGTGAAACAACACTCCCGTTTTCTTTTTCC TTTCTTTCTTTCTTTCTTTTTTTTTTTTTTTTTTTTTTTTGTTGAGACAGAGTTTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCG TGATCTCGGCTCACCGCAACCTCCGCCTCCCAGGTTCAAGCGATTCTCGTGCCTCAGCCTCTGGAGTAGCTGGGATTACAGGCATGCGCC ACCACACCCGGCTAATTTTGTACTTTTAGTAGAGATGGGGTTTCTCCATATTGGTCAGGCTGGTCCCGAACTCCTGACCTCAGGTGATCT GCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATAAGCCACCGAGCCCAGCCCCACACTCCTGTTTTCATAGCCCTTTTTTGTCT GTACTTTGGTACATATTCCCCAAATAAGATTATTATTTACATCTGTCATGATGAGGCAGTGATAGCAGCAAGTGTCACTTTGACCCTCAC CCTTGGAAAGTGGGCTATGCATAGCTAGAGTTAGAACAGGAGGTTCTAATCCTGCTTCCACAATTACTTCAGTAACAGGCTTTTGTATCC ATGATTACTTAAGCTGACTTAGATGCATTTTCTACCCTGTATTCTAGTGTACACAACACAAACACACATAAGCCCTTTACCTGTGGAGAA GAGGGAGATGGTTGATTCAGTGGGAGTGGGGAGTGGCAGAGGGTGCCTTAACTTTTTCTGGCTTGACCCCTACTTCCTTATGTGTTTCCT TCATATACCTCTGTCACTTTAGAGATGTAATCATGTCTGTTCCAAGTTGTATCGTTATTATCAAGAAGTCCTATAAATGTAGCAAATGTG ACTATTTTATAGAAATGCACAATAGTTTATAGGCCTTGGAGAAGTCTGATAATAGTATGTAAATATCCTTCATTGAAGTCATAGAACCTT CTAGTAGGAAGCTCCATAGGTGATAACTGCAAGAGGATTAATGTTTGTTTCTCCAGTAAACACCGGAAGCAAGGAATCAATCTGTCACTG TTTATCATTCAGTCTTGAGCACCGTTGGGTGTTGATAGGTTACTATAGACACTCCCCTTATAATTAATATACAGGACTCACAATTTAGGA TGTCTGATGGCCACTAGGGTACATCATAGAGACACTAGAGAGAAGAGAACAAATATAGCTCCATCAAAAAGCCTGCTTAATCTTTAACAA GTCTGAAATATTACTAAAATTCCAGTTACCGTGCAGCATAGTCAGTCTAAAAAGCACTGGGGAAAAAGGTGTCTTTTTGGTCTCTTTAAT TCTATTATGGCACATTTTAATATTATTCCACATGTGTGCAAACTATTTCTCAAGAGCAAAGTTTGAGGCTGGAGTTAAGAAAATAGAAAA ATTAAAACATTATTTTTTCTCATATAATATAATCTGACTACTAGTTCATGGATATAATAATTCTGGGAAAAATTTTAGATTAAACTATAA AATTGAAATCACCTTTGAAGAGTATATGGAATTGCTTCTTTCTATTAAAGCCAACCTACATTGGCAAAAAGTGTGGAGAAAATCAGTGTG CTCAATTCTTTTTGTAGAGTTTCATCTAAAATGTTGCAGGTAAAAAAGAAAACTTTAATTGGTACTTTCTACGGTGTGATTAGAAAAATT AGTATCTATCTCTGTTGGTTCTGCTGACTTGCTTCTTTCCACCGAATCTAAATGCAATGTCATAGGAGGAGGTTTGCTGTAAAAACATGT CTTTTTCTTTGGTGTATTCATTGTAATTATGGCTGGCAGTGAGAAGGTTCGGTAAGTCTCAATTTCTCTACCTCCTTTACTTGGAGAAAA >54911_54911_1_MRPL11-ST8SIA1_MRPL11_chr11_66204575_ENST00000310999_ST8SIA1_chr12_22402032_ENST00000396037_length(amino acids)=350AA_BP=158 MSKLGRAARGLRKPEVGGVIRAIVRAGLAMPGPPLGPVLGQRGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYF LKAAAGIEKGARQTGKEVAGLVTLKHVYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGIRVVKECNLPPLSSEYTKDVGSKSQLVT ANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTG -------------------------------------------------------------- >54911_54911_2_MRPL11-ST8SIA1_MRPL11_chr11_66204575_ENST00000310999_ST8SIA1_chr12_22402032_ENST00000539510_length(transcript)=1557nt_BP=567nt GTGAGGACCCTTGACCTCTGGCCCAAGATGGTGGCGCCCAGAGCTTCGCTCTTGCTGCTCCCCTGAGGTGAACTGAAGCCAGCAGCCCCG CATCATGTCAAAGCTCGGCCGGGCCGCCCGGGGCCTCAGGAAGCCCGAGGTCGGCGGTGTGATCCGGGCGATCGTGCGGGCAGGCCTGGC CATGCCCGGGCCCCCACTAGGCCCAGTGCTGGGTCAGAGAGGCGTTTCCATCAACCAGTTTTGCAAGGAGTTCAATGAGAGGACAAAGGA CATCAAGGAAGGCATTCCTCTGCCTACCAAGATTTTAGTGAAGCCTGACAGGACATTTGAAATTAAGATTGGACAGCCCACTGTTTCCTA CTTCCTGAAGGCAGCAGCTGGGATTGAAAAGGGGGCCCGGCAAACAGGGAAAGAGGTGGCAGGCCTGGTGACCTTGAAGCATGTGTATGA GATTGCCCGCATCAAAGCTCAGGATGAGGCATTTGCCCTGCAGGATGTACCCCTGTCGTCTGTTGTCCGCTCCATCATCGGGTCTGCCCG TTCTCTGGGCATTCGCGTGGTGAAGGAATGCAATCTCCCTCCTTTGTCAAGTGAATACACTAAGGATGTTGGATCCAAAAGTCAGTTAGT GACAGCTAATCCCAGCATAATTCGGCAAAGGTTTCAGAACCTTCTGTGGTCCAGAAAGACATTTGTGGACAACATGAAAATTTATAACCA CAGTTACATCTACATGCCTGCCTTTTCTATGAAGACAGGAACAGAGCCATCTTTGAGGGTTTATTATACACTGTCAGATGTTGGTGCCAA TCAAACAGTGCTGTTTGCCAACCCCAACTTTCTGCGTAGCATTGGAAAGTTCTGGAAAAGTAGAGGAATCCATGCCAAGCGCCTGTCCAC AGGACTTTTTCTGGTGAGCGCAGCTCTGGGTCTCTGTGAAGAGGTGGCCATCTATGGCTTCTGGCCCTTCTCTGTGAATATGCATGAGCA GCCCATCAGCCACCACTACTATGACAACGTCTTACCCTTTTCTGGCTTCCATGCCATGCCCGAGGAATTTCTCCAACTCTGGTATCTTCA TAAAATCGGTGCACTGAGAATGCAGCTGGACCCATGTGAAGATACCTCACTCCAGCCCACTTCCTAGGAACAATGGAAGAAGAAAGGACT GAACCAGGGTATTTTTGTTAGGTTTTCTATGTGACTCCAAGAGGGAATGGTCAAGTTGTTTCATGAGTTTGCATGGGCCCTTGGAAAAAC AGGAAAGGAGCAATGAAGATCCAAGCAAAACTTTACTTTCAGCGTTGGCTTGGAGGACAAATAAGAAATGAAACATCCTATGAAATACTT TATAGCACATGGCAGATTTGCAACTAGTAAAATGCTGGTGAAATGCTGTTGGTAAAGCACATGGTTCAAATCTAGAAGATGCAGTTCAAA AACAAGACAGACTCGAGTTGTTAGGGCTGAGGAACCAATCAAGGTAGAACAAAGAAAATGTTGGGGTAAAAGTGTTGCTGATTGTCAACA >54911_54911_2_MRPL11-ST8SIA1_MRPL11_chr11_66204575_ENST00000310999_ST8SIA1_chr12_22402032_ENST00000539510_length(amino acids)=350AA_BP=158 MSKLGRAARGLRKPEVGGVIRAIVRAGLAMPGPPLGPVLGQRGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYF LKAAAGIEKGARQTGKEVAGLVTLKHVYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGIRVVKECNLPPLSSEYTKDVGSKSQLVT ANPSIIRQRFQNLLWSRKTFVDNMKIYNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTG -------------------------------------------------------------- >54911_54911_3_MRPL11-ST8SIA1_MRPL11_chr11_66204575_ENST00000430466_ST8SIA1_chr12_22402032_ENST00000396037_length(transcript)=9230nt_BP=489nt GTGAGGACCCTTGACCTCTGGCCCAAGATGGTGGCGCCCAGAGCTTCGCTCTTGCTGCTCCCCTGAGGTGAACTGAAGCCAGCAGCCCCG CATCATGTCAAAGCTCGGCCGGGCCGCCCGGGGCCTCAGGAAGCCCGAGAGAGGCGTTTCCATCAACCAGTTTTGCAAGGAGTTCAATGA GAGGACAAAGGACATCAAGGAAGGCATTCCTCTGCCTACCAAGATTTTAGTGAAGCCTGACAGGACATTTGAAATTAAGATTGGACAGCC CACTGTTTCCTACTTCCTGAAGGCAGCAGCTGGGATTGAAAAGGGGGCCCGGCAAACAGGGAAAGAGGTGGCAGGCCTGGTGACCTTGAA GCATGTGTATGAGATTGCCCGCATCAAAGCTCAGGATGAGGCATTTGCCCTGCAGGATGTACCCCTGTCGTCTGTTGTCCGCTCCATCAT CGGGTCTGCCCGTTCTCTGGGCATTCGCGTGGTGAAGGAATGCAATCTCCCTCCTTTGTCAAGTGAATACACTAAGGATGTTGGATCCAA AAGTCAGTTAGTGACAGCTAATCCCAGCATAATTCGGCAAAGGTTTCAGAACCTTCTGTGGTCCAGAAAGACATTTGTGGACAACATGAA AATTTATAACCACAGTTACATCTACATGCCTGCCTTTTCTATGAAGACAGGAACAGAGCCATCTTTGAGGGTTTATTATACACTGTCAGA TGTTGGTGCCAATCAAACAGTGCTGTTTGCCAACCCCAACTTTCTGCGTAGCATTGGAAAGTTCTGGAAAAGTAGAGGAATCCATGCCAA GCGCCTGTCCACAGGACTTTTTCTGGTGAGCGCAGCTCTGGGTCTCTGTGAAGAGGTGGCCATCTATGGCTTCTGGCCCTTCTCTGTGAA TATGCATGAGCAGCCCATCAGCCACCACTACTATGACAACGTCTTACCCTTTTCTGGCTTCCATGCCATGCCCGAGGAATTTCTCCAACT CTGGTATCTTCATAAAATCGGTGCACTGAGAATGCAGCTGGACCCATGTGAAGATACCTCACTCCAGCCCACTTCCTAGGAACAATGGAA GAAGAAAGGACTGAACCAGGGTATTTTTGTTAGGTTTTCTATGTGACTCCAAGAGGGAATGGTCAAGTTGTTTCATGAGTTTGCATGGGC CCTTGGAAAAACAGGAAAGGAGCAATGAAGATCCAAGCAAAACTTTACTTTCAGCGTTGGCTTGGAGGACAAATAAGAAATGAAACATCC TATGAAATACTTTATAGCACATGGCAGATTTGCAACTAGTAAAATGCTGGTGAAATGCTGTTGGTAAAGCACATGGTTCAAATCTAGAAG ATGCAGTTCAAAAACAAGACAGACTCGAGTTGTTAGGGCTGAGGAACCAATCAAGGTAGAACAAAGAAAATGTTGGGGTAAAAGTGTTGC TGATTGTCAACACAAACTGGCTTAATAATATTAATAAGAACCTGTCTTATTAAGACTGGCTTTAGAACCGTAGGTTTTTTTAAAAAATTA TTATTTATTTTTGCCCTCTTTGGGGAAGTGGGTGGGTAGATTTAAAAAATCCCTTCCTGAGTAATAAAGATACAAAATGTTACTGCTGAT AATTGTGATTTGTTGAGCCACGTCTATATTAACTATAGCTCCCCTCTATTTTTAAAATTTTACATAAGAATTGCTTCTTCCTCTTTTGTC AAGTCCACAGAGACAATGTGAAGCATTATTGAATTTAGACTGTGTTGCTTCATAGTCTGGATAACAGGAGCCACTTTCCTTCCTCAGAAT TTAGGACATAAACCCAATTTTAGGTCTGCATTATGTAAGCCTGTTTGCATTGTCATTTTTATTTTAGTGCAAAAGACTACCAATATGAGT GAATTATTTGTTTGTAAATTGGCATAATTGTCTTCATAATTTAATGTTCAGAAATGCAGTAAAGCACGTTGATGAAAAGCTTAGTCTCTG TGGAAGACAGACCAGAAGACAAATCCCTTTTCTATCTACTGTGGCATATTCACTGCAAGGTAAAGGACATGTATGCATACATGCAAGAAT GAATTGAGCGAAACTTTGAATATGTTTCCTCTTTTGAGCTATTGTTATTTAGTAGTTACCTAAAAAAGAATACATTTTTACTAGTATACC ATTAAAAATGTAAAAGGCTTAACATGTATGCATACATGTAGACACACATACACACACACAAAGTTAAACAAAGCTCATTACTGTGCAACT ATGAAAGCTGAACTCATATGACCTGGTATGGCAAAAATTTGTAACCAGTGTTGGAGAATCACAAATGTGTTATGCACTATCCATTACATG TTGATATAAGACAACCGAGCTCACTGGTTGCCGCACATAATACCCATAGCAGCACAAGATGCAAGTCTTACCCCCAAATGCTTACCCGGA ATGAGCAGAATTGTCTTACTCATCCTGATTTTACCCAAAATCTCATGAATGGGCTTGCTGTTGAGCGTGGTCACACAAGGTATAGTTTGT ACAAGTAAAGAAATGTGAATTAGTAGCTATTTATTTCCTTAGTAGCAGGTAGGACTACTTAGCTTGTTACAACAGCTTTGATACACAGTA AGAAAACTCTACTGACAGATTACAAGCAGCCAAATGTGTTTACATTTCAGAGAAGGGTAAGGGAAGCCTCTCGTTGTCTTCATACTTTGG AATGTCTTAAGCTAAAATGTGACACTAGAGTTCAATTTCTTTTTTATTTTAAATGTCACTAAATTGTAGGTAAACTGTACCAAAAAGTTC TAGTTTAATTTTAACAGTAAAAACTCAGCATACCATGTTACCACGTAAACAATAATGGCTGGTATTTTCTGTGGGTTAATTTAACATGAC ATAAACATAGGAAAGCCCTTGGCAAAATTCTACATCATTGAAGTAGACCATTTCTAAATGCAATTAAATAGTGAGGTTATTATAAAAATT AGAATTTAAAATATGACTTGTTGATAGTGCAGATTATAATGTTACTTAGAAAGTTAAGAATTCGAGAGTAATGATGCTATTGGAGAACTG GTTTGCTATACGGCAGCAAAAACATAATGAGAATGTACCATGAAGAAATTGTGTTAAATATTCACTTTGAGTGAAACTTTAAATATGTTT CCTCTTTTGAGCTACTGTTATTTAGCAGTTACCTAAAAAAGAATACATTTTTACTAGTCTACCATTAAAAATATAAAAGGCTTAACAAAA ACGCATATAAAAGTTAATAAAATGTTACTCAGATTAGTACTTTAATTGTTAAAATGTAATTAATGAGCTCCATAGAGCCCATACATCACA GTTCCATTGAAAATATCATCTGGACTAGAATCTCTTAAACCCAGGAAGTGGAGGTTGCAGTGAGCCAAGATGGTGCCACTGCACTCCAGC CTGGGTGACAGGGCAAGACCCTGTCTCAAAAAAAAAAAAAAGAAAAGAAAAAGAAAGAAAATATTATGTGGAAATTTTTCATCTTTTTAT GATGCCTGGGATAGATTTATGCAGTAGATTTATATATAATGTTTAGTTTACAAACTTGTGAAACTATTTCATGTGGGTTCTGAAAGGCAA AACAGAAATGGCCAGTGCTGGTGATGTTTGATTAGACCAGCTCTTCTCAGCTGGGGTGATTCATTATCCCTCTCTGGTGACATTTGGCAA TGTCTGGAGACCAGAGACATTTTTTATTTTCATGACTCAAGGGTGCTAATAGCATGTACTTAGTAGAGGTTAGGGATCCTGCTAAAGATC TTACAATGCACAAGTCAGCCTCTCACAGCAAAATAATTATCCAGGCTGAGATGTCAGTAGTATCAAGGTTGACATCTCAGACCTGGATTA GACCTGGATTAGACCAAAATGAAATTTTGATTGTTCCACCTTGTCTTCACTTAAAGATAGATATACATGCTCACAGCATTCAAAATATGA CTACAATTTAATGAAAATATTTTCTTATGGTAGATTACAACTCACTAGATACACCATACATATGCCTTTTGGACATAATTGGTTAGATAG GAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGCATGAAGTTAGGCATCTCTATCCTTAACTGTGCTATGTGT TCCTAAGTAAGGACCTCGCTAGAATCATCCTGTAGAGTGCTCTGGAATACTCTATTATTAAGATCTTCAATTCTAAGCTCCCATTATCTT TCTTTGTTTATCTGAAATTAAGACCTTCAGAATTAGGCCTGGTACTTTTCCAGATTTGATCAGTTACATTTTGATATAACTGACTCTTAA AATTCAGCTTAGAAGACATTCAATAAGAAAATCTTTAATCACTTTTGGTGATGCACCTGCCAAGAGGGGGCATCACTTTGTACCATCAGA CTAATTAAAAAAATTGTTGTGTAGTCATAAAAATTAGGCTGATCCATAGGGGCAAAAGGAAGGGTGAAGAGACTAAAAACTAGTACCCTG ATAGAATTTTAGTTTTTATTAGCCTCGATTTGAGAACTGCATTGATTCCAAAGATCATGAAGGTAGGTGAAGGATTAAGTCATTCCATAA TTAAGAAAAGTAATGTTTATATGAAAGATTTTTATATGGACAATGACTCACAGACACATATGCTTTGTATAGAGGATTTTGCCAAAAGTT TATACAAAATTGCACATCTAAACTGCATAATTCTCATACAAGAAGTTAAGGAAGTGCTCACTGGATTTTGCTTCTGTATAGTTCACTTTT ATCTGTCTTCACAAGGGTAGGAAGTAAATGATCTCAAATGGCACATGTTCAGACAATACTGTGTTTGGCTTTGTGATGTCTCATGTCTTT CTCTTGGCTAAAAAAAATTGTTTAGGCTATATATAACTTGTACCTGAAGCAATCTGGACAACATGGCTTAAAATGGAAAATAACTGAAAA AATCCTGGGATTTTAAATTTGCCAAAAATACCCTTGGATTAGTCAAAGGCTTTACAAGAGTGTTATAGATGATCCAAAATGGAAACAATA TTGATAACATTTCTTTTCGTCAGCAGCTACATATTCCAGTTTTATAACTTTATTATATACATTTTTTGATTATTAATAGAAAGTCAGCCA TCCAGAGTTTTAACTTCTGTGGTTGAAATATTGACTTTGTGAAATTTTTCACTGACAAATACTTGTTAGGAGGGACCTAAGGGGGAGGGG AATGTTACCAGTCCACTGAAAACTTTAGGAAATGTTCATTGTGTTGTGTAAATACTTTCCCACCAGCACCAGGTAATATATTCTCTATGT TTGTAGAATTCCAAAGATCAAAAGCTGTAAGGACGTTTATGTGAACTTGACGCAAACTTGTGGAGGAATAAGGACTGAGAGTAATGTTGT GCTTTTTCTTTATCTTCCCGTCGTATAGGTCGACTCTCAGGTTATATGACTTTTATTGGGCACACGTCAGGGGTGGAAGTGGTAGAAGTG GGTTAACAATTTCAAGGCCTGGCAACCTAGGTCAAAACCTCTAATAAAGTCAGCAGTAAACATAACTAGCAACTTCATTCCACTATGTGC TAGGAGGAGGGTGAGGCAAGTTGAAAGGAGATGACCCTATCCCCACACTCTCAGGATGTAAAAGGGCAGAGTGCTCTCTACCCTTAACCT TGGCTTTTTAGCACCGTCAGTCTCTGTCCTCTCCCAGGAGAGCTGCCTTGGCTCCAGAGTTGAGCTAGTAGCATTGTGACTAGAGAGGTA GTGTGGAAATTCGCTGAGGACCTCAAAATTTTACACTGCCTTAAACTGTTTTGTTTTTGCTTAAACTCGTGCTGTCTAAATGTGGGTGTT TTGTGGCAGAGTCTGATCACCCCGACCTAGTTATAGCCCTGCCAGTGATTCTAAAGTGGAACTTTTCCCCCTCATTCATATGGATAGTCT GAGTCCTTGAAGCTAGGGAGATATCAAATATTCTACCAGTTCCTACATAGCTTCTTTAAAAGTCCTAGAGACTAACTCACAGGAAGTCTG AAGCCCAGAGCGTCTGTTTATAAACTCCTAAATATGAGGCCACAATATTTAGGTTGAGCACTAGAAAATTTCTATTTTGCAAGTGGAAGG AGACTTGAATCTATAATTGCTGTAGCTTTTTTTCCCTTCTATCATAAGAAAATGGATACCATCTGCTTTACCCTCAGCCCAGACTTGTCT TTTGAATTTTTTACATACATCTTAGGGGTGAGAGATTGAAACAAGTGCATGAATGAAAAGCTTATTGAAACATAACACAGCCCCTGCTCA CCATTTCAGTAAGGGAAAATACATGTTTCTGTTTCCCTCTAATTTGTTTTCTCTGGTGCCAACATTTCTGATTTCTTCTGTCTCTAATAC ATAAGGAATAAATACCATATTTTAAATTGACTTACATGCCTGCGAGCATTTGCCAGATAATCAAAGCCTATGACTCTAACTTTTTAAAGC ACAGAAGAGGAATTATATTTTATGGTCACTCCTCTGTGTTTCTATTGATCTCTATATTGTGCTAAAATTCTTTCAGGTAATTTTTTTCTT GTTGAAGCTGTGGGATATAATCAATGATGCCAAGCTGTCTGAGAATTTTATAGAATAATATCCAAATATATTGATCCTGCCTCTTTCTGC TTCTATGTAATTAAACTTTCTTTTGATGTTTATTTTTAAAATGTATGCTTCACACAACACCAATAAACATCTAAGAGATGTGATATAATC CAAGGCAAAGAAAAGTAAGAATCAGTTAATGTCTATTTTATCTGCACAGCATTACGAACAGAAAATTGTAATAAAAAAAGGTTTAACCAA ACTGAAAAAAAGAGAGACAAAATCTTGGTTTTAATTTGAAAAGATGATTGGGAGTGATCTCAGAAGAGAGTTCAGCAGGAAGCAAGGAAG AGGCTGTTGACCTTGAGTGCAGCCTCAAGAATGGAACCTTTTTGAAATATTTTAAAGGAAATATCTTGTCATCCAGCTGTTATGGTTAAT AATGAATAGTTTTCTCTGGGTGAAGCTTATCCATTGCACACCTGATGTGCTGGCCCCTGCGATTTCCCCAAATGTTGGAATGTTGCCTGC ATAATTTGTGGTAATGGGGGACTGTGTTCCTGCTTTTACCTGGTTACAAAAAACAAAACAAAACAAAACAAAACAACAAACAGAAAAAAA AAGAGAGAAAAGATGCTAGAGGAAGCAGTGTGACAGACAGATCATGAGATGCTGACGGAGAGAACAGAGTGGTACCTGTTTACCCACTTG GACCATGACAGTATCAAGGCTCCACCCCTTGCTGTCCCTTCCCAAGAGGTGCTCTCCTGGGAGTTTGATCACAGTGAAACAACACTCCCG TTTTCTTTTTCCTTTCTTTCTTTCTTTCTTTTTTTTTTTTTTTTTTTTTTTTGTTGAGACAGAGTTTTTTGCTCTTGTTGCCCAGGCTGG AGTGCAATGGCGTGATCTCGGCTCACCGCAACCTCCGCCTCCCAGGTTCAAGCGATTCTCGTGCCTCAGCCTCTGGAGTAGCTGGGATTA CAGGCATGCGCCACCACACCCGGCTAATTTTGTACTTTTAGTAGAGATGGGGTTTCTCCATATTGGTCAGGCTGGTCCCGAACTCCTGAC CTCAGGTGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATAAGCCACCGAGCCCAGCCCCACACTCCTGTTTTCATAGC CCTTTTTTGTCTGTACTTTGGTACATATTCCCCAAATAAGATTATTATTTACATCTGTCATGATGAGGCAGTGATAGCAGCAAGTGTCAC TTTGACCCTCACCCTTGGAAAGTGGGCTATGCATAGCTAGAGTTAGAACAGGAGGTTCTAATCCTGCTTCCACAATTACTTCAGTAACAG GCTTTTGTATCCATGATTACTTAAGCTGACTTAGATGCATTTTCTACCCTGTATTCTAGTGTACACAACACAAACACACATAAGCCCTTT ACCTGTGGAGAAGAGGGAGATGGTTGATTCAGTGGGAGTGGGGAGTGGCAGAGGGTGCCTTAACTTTTTCTGGCTTGACCCCTACTTCCT TATGTGTTTCCTTCATATACCTCTGTCACTTTAGAGATGTAATCATGTCTGTTCCAAGTTGTATCGTTATTATCAAGAAGTCCTATAAAT GTAGCAAATGTGACTATTTTATAGAAATGCACAATAGTTTATAGGCCTTGGAGAAGTCTGATAATAGTATGTAAATATCCTTCATTGAAG TCATAGAACCTTCTAGTAGGAAGCTCCATAGGTGATAACTGCAAGAGGATTAATGTTTGTTTCTCCAGTAAACACCGGAAGCAAGGAATC AATCTGTCACTGTTTATCATTCAGTCTTGAGCACCGTTGGGTGTTGATAGGTTACTATAGACACTCCCCTTATAATTAATATACAGGACT CACAATTTAGGATGTCTGATGGCCACTAGGGTACATCATAGAGACACTAGAGAGAAGAGAACAAATATAGCTCCATCAAAAAGCCTGCTT AATCTTTAACAAGTCTGAAATATTACTAAAATTCCAGTTACCGTGCAGCATAGTCAGTCTAAAAAGCACTGGGGAAAAAGGTGTCTTTTT GGTCTCTTTAATTCTATTATGGCACATTTTAATATTATTCCACATGTGTGCAAACTATTTCTCAAGAGCAAAGTTTGAGGCTGGAGTTAA GAAAATAGAAAAATTAAAACATTATTTTTTCTCATATAATATAATCTGACTACTAGTTCATGGATATAATAATTCTGGGAAAAATTTTAG ATTAAACTATAAAATTGAAATCACCTTTGAAGAGTATATGGAATTGCTTCTTTCTATTAAAGCCAACCTACATTGGCAAAAAGTGTGGAG AAAATCAGTGTGCTCAATTCTTTTTGTAGAGTTTCATCTAAAATGTTGCAGGTAAAAAAGAAAACTTTAATTGGTACTTTCTACGGTGTG ATTAGAAAAATTAGTATCTATCTCTGTTGGTTCTGCTGACTTGCTTCTTTCCACCGAATCTAAATGCAATGTCATAGGAGGAGGTTTGCT GTAAAAACATGTCTTTTTCTTTGGTGTATTCATTGTAATTATGGCTGGCAGTGAGAAGGTTCGGTAAGTCTCAATTTCTCTACCTCCTTT >54911_54911_3_MRPL11-ST8SIA1_MRPL11_chr11_66204575_ENST00000430466_ST8SIA1_chr12_22402032_ENST00000396037_length(amino acids)=324AA_BP=132 MSKLGRAARGLRKPERGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYFLKAAAGIEKGARQTGKEVAGLVTLKH VYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGIRVVKECNLPPLSSEYTKDVGSKSQLVTANPSIIRQRFQNLLWSRKTFVDNMKI YNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNM -------------------------------------------------------------- >54911_54911_4_MRPL11-ST8SIA1_MRPL11_chr11_66204575_ENST00000430466_ST8SIA1_chr12_22402032_ENST00000539510_length(transcript)=1479nt_BP=489nt GTGAGGACCCTTGACCTCTGGCCCAAGATGGTGGCGCCCAGAGCTTCGCTCTTGCTGCTCCCCTGAGGTGAACTGAAGCCAGCAGCCCCG CATCATGTCAAAGCTCGGCCGGGCCGCCCGGGGCCTCAGGAAGCCCGAGAGAGGCGTTTCCATCAACCAGTTTTGCAAGGAGTTCAATGA GAGGACAAAGGACATCAAGGAAGGCATTCCTCTGCCTACCAAGATTTTAGTGAAGCCTGACAGGACATTTGAAATTAAGATTGGACAGCC CACTGTTTCCTACTTCCTGAAGGCAGCAGCTGGGATTGAAAAGGGGGCCCGGCAAACAGGGAAAGAGGTGGCAGGCCTGGTGACCTTGAA GCATGTGTATGAGATTGCCCGCATCAAAGCTCAGGATGAGGCATTTGCCCTGCAGGATGTACCCCTGTCGTCTGTTGTCCGCTCCATCAT CGGGTCTGCCCGTTCTCTGGGCATTCGCGTGGTGAAGGAATGCAATCTCCCTCCTTTGTCAAGTGAATACACTAAGGATGTTGGATCCAA AAGTCAGTTAGTGACAGCTAATCCCAGCATAATTCGGCAAAGGTTTCAGAACCTTCTGTGGTCCAGAAAGACATTTGTGGACAACATGAA AATTTATAACCACAGTTACATCTACATGCCTGCCTTTTCTATGAAGACAGGAACAGAGCCATCTTTGAGGGTTTATTATACACTGTCAGA TGTTGGTGCCAATCAAACAGTGCTGTTTGCCAACCCCAACTTTCTGCGTAGCATTGGAAAGTTCTGGAAAAGTAGAGGAATCCATGCCAA GCGCCTGTCCACAGGACTTTTTCTGGTGAGCGCAGCTCTGGGTCTCTGTGAAGAGGTGGCCATCTATGGCTTCTGGCCCTTCTCTGTGAA TATGCATGAGCAGCCCATCAGCCACCACTACTATGACAACGTCTTACCCTTTTCTGGCTTCCATGCCATGCCCGAGGAATTTCTCCAACT CTGGTATCTTCATAAAATCGGTGCACTGAGAATGCAGCTGGACCCATGTGAAGATACCTCACTCCAGCCCACTTCCTAGGAACAATGGAA GAAGAAAGGACTGAACCAGGGTATTTTTGTTAGGTTTTCTATGTGACTCCAAGAGGGAATGGTCAAGTTGTTTCATGAGTTTGCATGGGC CCTTGGAAAAACAGGAAAGGAGCAATGAAGATCCAAGCAAAACTTTACTTTCAGCGTTGGCTTGGAGGACAAATAAGAAATGAAACATCC TATGAAATACTTTATAGCACATGGCAGATTTGCAACTAGTAAAATGCTGGTGAAATGCTGTTGGTAAAGCACATGGTTCAAATCTAGAAG ATGCAGTTCAAAAACAAGACAGACTCGAGTTGTTAGGGCTGAGGAACCAATCAAGGTAGAACAAAGAAAATGTTGGGGTAAAAGTGTTGC >54911_54911_4_MRPL11-ST8SIA1_MRPL11_chr11_66204575_ENST00000430466_ST8SIA1_chr12_22402032_ENST00000539510_length(amino acids)=324AA_BP=132 MSKLGRAARGLRKPERGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYFLKAAAGIEKGARQTGKEVAGLVTLKH VYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGIRVVKECNLPPLSSEYTKDVGSKSQLVTANPSIIRQRFQNLLWSRKTFVDNMKI YNHSYIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNM -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for MRPL11-ST8SIA1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for MRPL11-ST8SIA1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for MRPL11-ST8SIA1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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