Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:MRPL33-BRE (FusionGDB2 ID:55003)

Fusion Gene Summary for MRPL33-BRE

Fusion gene summary

Fusion gene information	Fusion gene name: MRPL33-BRE
	Fusion gene ID: 55003
		Hgene	Tgene
	Gene symbol	MRPL33	BRE
	Gene ID	9553	9577
	Gene name	mitochondrial ribosomal protein L33	BRISC and BRCA1 A complex member 2
	Synonyms	C2orf1\|L33mt\|MRP-L33\|RPL33L	BRCC4\|BRCC45\|BRE
	Cytomap	2p23.2	2p23.2
	Type of gene	protein-coding	protein-coding
	Description	39S ribosomal protein L33, mitochondrialmitochondrial large ribosomal subunit protein bL33m	BRISC and BRCA1-A complex member 2BRCA1-A complex subunit BREBRCA1/BRCA2-containing complex subunit 45BRCA1/BRCA2-containing complex, subunit 4brain and reproductive organ-expressed (TNFRSF1A modulator)brain and reproductive organ-expressed protein
	Modification date	20200313	20200313
	UniProtAcc	O75394	.
	Ensembl transtripts involved in fusion gene	ENST00000483992, ENST00000296102, ENST00000379666,	ENST00000342045, ENST00000344773, ENST00000361704, ENST00000379624, ENST00000379632, ENST00000603461,
Fusion gene scores	* DoF score	10 X 8 X 9=720	20 X 20 X 12=4800
	# samples	15	30
	** MAII score	log2(15/720*10)=-2.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(30/4800*10)=-4 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: MRPL33 [Title/Abstract] AND BRE [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	MRPL33(27995559)-BRE(28117400), # samples:54
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	BRE	GO:0043066	negative regulation of apoptotic process	15465831

Fusion gene breakpoints across MRPL33 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across BRE (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	Non-Cancer	TCGA-06-0675-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-06-0678-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-06-0680-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-06-0681-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-A6-2683-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-AC-A2FF-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-B0-5690-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-B0-5701-11A	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
ChimerDB4	Non-Cancer	TCGA-B2-5641-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A0BS-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A0BT-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A0C0-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A0C3-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A0DL-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A18Q-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A1EO-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A1EU-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A1F6-11B	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
ChimerDB4	Non-Cancer	TCGA-BH-A1FE-11B	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A1FM-11B	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A1FU-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A203-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A204-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BH-A209-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-BL-A13J-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-CJ-5680-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-CJ-6030-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-CW-6088-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-CZ-5451-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-CZ-5465-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-CZ-5466-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-CZ-5469-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-CZ-5986-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-CZ-5987-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-E2-A15M-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-E2-A1L7-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-E2-A1LS-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-E9-A1N4-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-E9-A1NA-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-E9-A1RB-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-E9-A1RC-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-E9-A1RI-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-FU-A3EO-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-GI-A2C9-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KL-8339-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KN-8419-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KN-8419-11A	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
ChimerDB4	Non-Cancer	TCGA-KN-8425-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KN-8426-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KN-8428-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KN-8431-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KN-8432-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KN-8433-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KN-8434-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KN-8436-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KO-8403-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
ChimerDB4	Non-Cancer	TCGA-KO-8415-11A	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+

Top

Fusion Gene ORF analysis for MRPL33-BRE

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
3UTR-3CDS	ENST00000483992	ENST00000342045	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
3UTR-3CDS	ENST00000483992	ENST00000344773	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
3UTR-3CDS	ENST00000483992	ENST00000361704	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
3UTR-3CDS	ENST00000483992	ENST00000379624	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
3UTR-3CDS	ENST00000483992	ENST00000379632	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
3UTR-3UTR	ENST00000483992	ENST00000603461	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
3UTR-5UTR	ENST00000483992	ENST00000342045	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
3UTR-5UTR	ENST00000483992	ENST00000344773	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
3UTR-5UTR	ENST00000483992	ENST00000361704	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
3UTR-5UTR	ENST00000483992	ENST00000379624	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
3UTR-5UTR	ENST00000483992	ENST00000379632	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
3UTR-intron	ENST00000483992	ENST00000603461	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-3UTR	ENST00000296102	ENST00000603461	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
5CDS-3UTR	ENST00000379666	ENST00000603461	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
5CDS-5UTR	ENST00000296102	ENST00000342045	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-5UTR	ENST00000296102	ENST00000344773	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-5UTR	ENST00000296102	ENST00000361704	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-5UTR	ENST00000296102	ENST00000379624	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-5UTR	ENST00000296102	ENST00000379632	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-5UTR	ENST00000379666	ENST00000342045	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-5UTR	ENST00000379666	ENST00000344773	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-5UTR	ENST00000379666	ENST00000361704	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-5UTR	ENST00000379666	ENST00000379624	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-5UTR	ENST00000379666	ENST00000379632	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-intron	ENST00000296102	ENST00000603461	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
5CDS-intron	ENST00000379666	ENST00000603461	MRPL33	chr2	27995559	+	BRE	chr2	28117400	+
In-frame	ENST00000296102	ENST00000342045	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
In-frame	ENST00000296102	ENST00000344773	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
In-frame	ENST00000296102	ENST00000361704	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
In-frame	ENST00000296102	ENST00000379624	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
In-frame	ENST00000296102	ENST00000379632	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
In-frame	ENST00000379666	ENST00000342045	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
In-frame	ENST00000379666	ENST00000344773	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
In-frame	ENST00000379666	ENST00000361704	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
In-frame	ENST00000379666	ENST00000379624	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+
In-frame	ENST00000379666	ENST00000379632	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000379666	MRPL33	chr2	27995559	+	ENST00000344773	BRE	chr2	28152699	+	1688	102	4	1221	405
ENST00000379666	MRPL33	chr2	27995559	+	ENST00000379624	BRE	chr2	28152699	+	1514	102	4	1125	373
ENST00000379666	MRPL33	chr2	27995559	+	ENST00000342045	BRE	chr2	28152699	+	1514	102	4	1125	373
ENST00000379666	MRPL33	chr2	27995559	+	ENST00000379632	BRE	chr2	28152699	+	1586	102	4	1104	366
ENST00000379666	MRPL33	chr2	27995559	+	ENST00000361704	BRE	chr2	28152699	+	1586	102	4	1104	366
ENST00000296102	MRPL33	chr2	27995559	+	ENST00000344773	BRE	chr2	28152699	+	1688	102	4	1221	405
ENST00000296102	MRPL33	chr2	27995559	+	ENST00000379624	BRE	chr2	28152699	+	1514	102	4	1125	373
ENST00000296102	MRPL33	chr2	27995559	+	ENST00000342045	BRE	chr2	28152699	+	1514	102	4	1125	373
ENST00000296102	MRPL33	chr2	27995559	+	ENST00000379632	BRE	chr2	28152699	+	1586	102	4	1104	366
ENST00000296102	MRPL33	chr2	27995559	+	ENST00000361704	BRE	chr2	28152699	+	1586	102	4	1104	366

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000379666	ENST00000344773	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+	0.005442054	0.994558
ENST00000379666	ENST00000379624	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+	0.001945221	0.99805486
ENST00000379666	ENST00000342045	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+	0.001945221	0.99805486
ENST00000379666	ENST00000379632	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+	0.00199752	0.99800247
ENST00000379666	ENST00000361704	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+	0.00199752	0.99800247
ENST00000296102	ENST00000344773	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+	0.005442054	0.994558
ENST00000296102	ENST00000379624	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+	0.001945221	0.99805486
ENST00000296102	ENST00000342045	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+	0.001945221	0.99805486
ENST00000296102	ENST00000379632	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+	0.00199752	0.99800247
ENST00000296102	ENST00000361704	MRPL33	chr2	27995559	+	BRE	chr2	28152699	+	0.00199752	0.99800247

Top

Fusion Genomic Features for MRPL33-BRE

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for MRPL33-BRE

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:27995559/chr2:28117400)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
MRPL33 O75394	.
	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

BRE

chr2:27995559

chr2:28152699

ENST00000342045

275_364

384.0

Region

Note=UEV-like 2

Tgene

BRE

chr2:27995559

chr2:28152699

ENST00000344773

275_364

528.6666666666666

Region

Note=UEV-like 2

Tgene

BRE

chr2:27995559

chr2:28152699

ENST00000361704

275_364

511.0

Region

Note=UEV-like 2

Tgene

BRE

chr2:27995559

chr2:28152699

ENST00000379624

275_364

384.0

Region

Note=UEV-like 2

Tgene

BRE

chr2:27995559

chr2:28152699

ENST00000379632

275_364

511.0

Region

Note=UEV-like 2

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

BRE

chr2:27995559

chr2:28152699

ENST00000342045

30_147

384.0

Region

Note=UEV-like 1

Tgene

BRE

chr2:27995559

chr2:28152699

ENST00000344773

30_147

528.6666666666666

Region

Note=UEV-like 1

Tgene

BRE

chr2:27995559

chr2:28152699

ENST00000361704

30_147

511.0

Region

Note=UEV-like 1

Tgene

BRE

chr2:27995559

chr2:28152699

ENST00000379624

30_147

384.0

Region

Note=UEV-like 1

Tgene

BRE

chr2:27995559

chr2:28152699

ENST00000379632

30_147

511.0

Region

Note=UEV-like 1

Top

Fusion Gene Sequence for MRPL33-BRE

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>55003_55003_1_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000296102_BRE_chr2_28152699_ENST00000342045_length(transcript)=1514nt_BP=102nt
GCAGTTGTTGTTGGTTGGGGGCCTTTTGGCCGGTGACGGAGACTGCCCAGGTGTGGTCACCATGTTCCTCTCCGCGGTCTTCTTTGCCAA
GAGCAAGTCAAACTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTG
GGATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTT
GCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATG
TAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGC
TGGGAAAAAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGATTTCAGCAATATCCCCACATACCTTCT
CAAGGATGTAAATGAAGACCCTGGAGAAGATGTGGCCCTCCTCTCTGTTAGTTTTGAGGACACTGAAGCCACCCAGGTGTACCCCAAGCT
GTACTTGTCACCTCGAATTGAGCATGCACTTGGAGGCTCCTCAGCTCTTCATATCCCAGCTTTTCCAGGAGGAGGATGTCTCATTGATTA
CGTTCCTCAAGTATGCCACCTGCTCACCAACAAGGTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCTGCTTTTCT
CAGTCACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTGCTGCTGATGTGGAAAGATTTTTGTTTTCT
TGTACACATTGACCTGCCTCTGTTTTTCCCTCGAGACCAGCCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCT
TTACTCCCAGGCCCAAAAAAATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAAAGAGCAAAGGCTTATTTCAAAACCTT
TGTCCCTCAGTTCCAGGAGGCAGCATTTGCCAATGGAAAGCTCTAGGAAACACCAGTCTTGAGAGGTGGCCAGCCAGACTGCCTGTCCAC
ATGCGTGTCAGCACATACAGCCGCTTCCTGGAAGCCGCCTGGAATGTCTTCACGGCAGCGTTTTGCTCACACAGCAGCTTTTGCACGCCC
CAGGCAGCCCCGACTGCTGAAATCCAACTTGAGCTGGCTGGTGGTCCCTGGATCCTAGAGCCCTTCACTTCGGGTTACTCCCTCTTTCTT
GCCTCTATTTCTTAGTTGGAAGAAATAAACTCACAAATTATGGTGCAGTAATTTTCCGGGGAAAGTAAAGCCTCAGGAATGCCCACGCCT

>55003_55003_1_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000296102_BRE_chr2_28152699_ENST00000342045_length(amino acids)=373AA_BP=1
MLLVGGLLAGDGDCPGVVTMFLSAVFFAKSKSNCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQ
NLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLK
DVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLS
HFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKAYFKTFV

--------------------------------------------------------------
>55003_55003_2_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000296102_BRE_chr2_28152699_ENST00000344773_length(transcript)=1688nt_BP=102nt
GCAGTTGTTGTTGGTTGGGGGCCTTTTGGCCGGTGACGGAGACTGCCCAGGTGTGGTCACCATGTTCCTCTCCGCGGTCTTCTTTGCCAA
GAGCAAGTCAAACTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTG
GGATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTT
GCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATG
TAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGC
TGGGAAAAAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGATTTCAGCAATATCCCCACATACCTTCT
CAAGGATGTAAATGAAGACCCTGGAGAAGATGTGGCCCTCCTCTCTGTTAGTTTTGAGGACACTGAAGCCACCCAGGTGTACCCCAAGCT
GTACTTGTCACCTCGAATTGAGCATGCACTTGGAGGCTCCTCAGCTCTTCATATCCCAGCTTTTCCAGGAGGAGGATGTCTCATTGATTA
CGTTCCTCAAGTATGCCACCTGCTCACCAACAAGGTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCTGCTTTTCT
CAGTCACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTGCTGCTGATGTGGAAAGATTTTTGTTTTCT
TGTACACATTGACCTGCCTCTGTTTTTCCCTCGAGACCAGCCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCT
TTACTCCCAGGCCCAAAAAAATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAAAGAGCAAAGGGATGCCAAGGGAGCAG
AGATGCCTGCAGCCCGTGGGAGCAAGTCCTGGCCTTTGCAGTTGCAAAAACTGGCTGCAAGCTGCTCCAGCCCCAGAGGAACTGGCCAAG
CTCCAGAGGGCCTCCTTGGAGGGCCTCAGAGGGAGAGAGAACTGCTCAGTAATTTTGATCACTTTGGGCTTATTTCAAAACCTTTGTCCC
TCAGTTCCAGGAGGCAGCATTTGCCAATGGAAAGCTCTAGGAAACACCAGTCTTGAGAGGTGGCCAGCCAGACTGCCTGTCCACATGCGT
GTCAGCACATACAGCCGCTTCCTGGAAGCCGCCTGGAATGTCTTCACGGCAGCGTTTTGCTCACACAGCAGCTTTTGCACGCCCCAGGCA
GCCCCGACTGCTGAAATCCAACTTGAGCTGGCTGGTGGTCCCTGGATCCTAGAGCCCTTCACTTCGGGTTACTCCCTCTTTCTTGCCTCT
ATTTCTTAGTTGGAAGAAATAAACTCACAAATTATGGTGCAGTAATTTTCCGGGGAAAGTAAAGCCTCAGGAATGCCCACGCCTTTCTTC

>55003_55003_2_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000296102_BRE_chr2_28152699_ENST00000344773_length(amino acids)=405AA_BP=1
MLLVGGLLAGDGDCPGVVTMFLSAVFFAKSKSNCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQ
NLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLK
DVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLS
HFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKGCQGSRD

--------------------------------------------------------------
>55003_55003_3_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000296102_BRE_chr2_28152699_ENST00000361704_length(transcript)=1586nt_BP=102nt
GCAGTTGTTGTTGGTTGGGGGCCTTTTGGCCGGTGACGGAGACTGCCCAGGTGTGGTCACCATGTTCCTCTCCGCGGTCTTCTTTGCCAA
GAGCAAGTCAAACTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTG
GGATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTT
GCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATG
TAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGC
TGGGAAAAAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGATTTCAGCAATATCCCCACATACCTTCT
CAAGGATGTAAATGAAGACCCTGGAGAAGATGTGGCCCTCCTCTCTGTTAGTTTTGAGGACACTGAAGCCACCCAGGTGTACCCCAAGCT
GTACTTGTCACCTCGAATTGAGCATGCACTTGGAGGCTCCTCAGCTCTTCATATCCCAGCTTTTCCAGGAGGAGGATGTCTCATTGATTA
CGTTCCTCAAGTATGCCACCTGCTCACCAACAAGGTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCTGCTTTTCT
CAGTCACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTGCTGCTGATGTGGAAAGATTTTTGTTTTCT
TGTACACATTGACCTGCCTCTGTTTTTCCCTCGAGACCAGCCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCT
TTACTCCCAGGCCCAAAAAAATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAAAGAGCAAAAAGAGAGAGCAACAGAGA
TGGGGAGGAATCCAGCTCTGCCTGACATCCAGGCATCCTCTCCAAATTGCATAGGGCTTATTTCAAAACCTTTGTCCCTCAGTTCCAGGA
GGCAGCATTTGCCAATGGAAAGCTCTAGGAAACACCAGTCTTGAGAGGTGGCCAGCCAGACTGCCTGTCCACATGCGTGTCAGCACATAC
AGCCGCTTCCTGGAAGCCGCCTGGAATGTCTTCACGGCAGCGTTTTGCTCACACAGCAGCTTTTGCACGCCCCAGGCAGCCCCGACTGCT
GAAATCCAACTTGAGCTGGCTGGTGGTCCCTGGATCCTAGAGCCCTTCACTTCGGGTTACTCCCTCTTTCTTGCCTCTATTTCTTAGTTG
GAAGAAATAAACTCACAAATTATGGTGCAGTAATTTTCCGGGGAAAGTAAAGCCTCAGGAATGCCCACGCCTTTCTTCCAAAGCCTTTGT

>55003_55003_3_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000296102_BRE_chr2_28152699_ENST00000361704_length(amino acids)=366AA_BP=1
MLLVGGLLAGDGDCPGVVTMFLSAVFFAKSKSNCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQ
NLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLK
DVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLS
HFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKRESNRDG

--------------------------------------------------------------
>55003_55003_4_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000296102_BRE_chr2_28152699_ENST00000379624_length(transcript)=1514nt_BP=102nt
GCAGTTGTTGTTGGTTGGGGGCCTTTTGGCCGGTGACGGAGACTGCCCAGGTGTGGTCACCATGTTCCTCTCCGCGGTCTTCTTTGCCAA
GAGCAAGTCAAACTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTG
GGATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTT
GCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATG
TAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGC
TGGGAAAAAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGATTTCAGCAATATCCCCACATACCTTCT
CAAGGATGTAAATGAAGACCCTGGAGAAGATGTGGCCCTCCTCTCTGTTAGTTTTGAGGACACTGAAGCCACCCAGGTGTACCCCAAGCT
GTACTTGTCACCTCGAATTGAGCATGCACTTGGAGGCTCCTCAGCTCTTCATATCCCAGCTTTTCCAGGAGGAGGATGTCTCATTGATTA
CGTTCCTCAAGTATGCCACCTGCTCACCAACAAGGTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCTGCTTTTCT
CAGTCACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTGCTGCTGATGTGGAAAGATTTTTGTTTTCT
TGTACACATTGACCTGCCTCTGTTTTTCCCTCGAGACCAGCCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCT
TTACTCCCAGGCCCAAAAAAATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAAAGAGCAAAGGCTTATTTCAAAACCTT
TGTCCCTCAGTTCCAGGAGGCAGCATTTGCCAATGGAAAGCTCTAGGAAACACCAGTCTTGAGAGGTGGCCAGCCAGACTGCCTGTCCAC
ATGCGTGTCAGCACATACAGCCGCTTCCTGGAAGCCGCCTGGAATGTCTTCACGGCAGCGTTTTGCTCACACAGCAGCTTTTGCACGCCC
CAGGCAGCCCCGACTGCTGAAATCCAACTTGAGCTGGCTGGTGGTCCCTGGATCCTAGAGCCCTTCACTTCGGGTTACTCCCTCTTTCTT
GCCTCTATTTCTTAGTTGGAAGAAATAAACTCACAAATTATGGTGCAGTAATTTTCCGGGGAAAGTAAAGCCTCAGGAATGCCCACGCCT

>55003_55003_4_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000296102_BRE_chr2_28152699_ENST00000379624_length(amino acids)=373AA_BP=1
MLLVGGLLAGDGDCPGVVTMFLSAVFFAKSKSNCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQ
NLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLK
DVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLS
HFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKAYFKTFV

--------------------------------------------------------------
>55003_55003_5_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000296102_BRE_chr2_28152699_ENST00000379632_length(transcript)=1586nt_BP=102nt
GCAGTTGTTGTTGGTTGGGGGCCTTTTGGCCGGTGACGGAGACTGCCCAGGTGTGGTCACCATGTTCCTCTCCGCGGTCTTCTTTGCCAA
GAGCAAGTCAAACTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTG
GGATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTT
GCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATG
TAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGC
TGGGAAAAAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGATTTCAGCAATATCCCCACATACCTTCT
CAAGGATGTAAATGAAGACCCTGGAGAAGATGTGGCCCTCCTCTCTGTTAGTTTTGAGGACACTGAAGCCACCCAGGTGTACCCCAAGCT
GTACTTGTCACCTCGAATTGAGCATGCACTTGGAGGCTCCTCAGCTCTTCATATCCCAGCTTTTCCAGGAGGAGGATGTCTCATTGATTA
CGTTCCTCAAGTATGCCACCTGCTCACCAACAAGGTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCTGCTTTTCT
CAGTCACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTGCTGCTGATGTGGAAAGATTTTTGTTTTCT
TGTACACATTGACCTGCCTCTGTTTTTCCCTCGAGACCAGCCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCT
TTACTCCCAGGCCCAAAAAAATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAAAGAGCAAAAAGAGAGAGCAACAGAGA
TGGGGAGGAATCCAGCTCTGCCTGACATCCAGGCATCCTCTCCAAATTGCATAGGGCTTATTTCAAAACCTTTGTCCCTCAGTTCCAGGA
GGCAGCATTTGCCAATGGAAAGCTCTAGGAAACACCAGTCTTGAGAGGTGGCCAGCCAGACTGCCTGTCCACATGCGTGTCAGCACATAC
AGCCGCTTCCTGGAAGCCGCCTGGAATGTCTTCACGGCAGCGTTTTGCTCACACAGCAGCTTTTGCACGCCCCAGGCAGCCCCGACTGCT
GAAATCCAACTTGAGCTGGCTGGTGGTCCCTGGATCCTAGAGCCCTTCACTTCGGGTTACTCCCTCTTTCTTGCCTCTATTTCTTAGTTG
GAAGAAATAAACTCACAAATTATGGTGCAGTAATTTTCCGGGGAAAGTAAAGCCTCAGGAATGCCCACGCCTTTCTTCCAAAGCCTTTGT

>55003_55003_5_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000296102_BRE_chr2_28152699_ENST00000379632_length(amino acids)=366AA_BP=1
MLLVGGLLAGDGDCPGVVTMFLSAVFFAKSKSNCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQ
NLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLK
DVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLS
HFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKRESNRDG

--------------------------------------------------------------
>55003_55003_6_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000379666_BRE_chr2_28152699_ENST00000342045_length(transcript)=1514nt_BP=102nt
GCAGTTGTTGTTGGTTGGGGGCCTTTTGGCCGGTGACGGAGACTGCCCAGGTGTGGTCACCATGTTCCTCTCCGCGGTCTTCTTTGCCAA
GAGCAAGTCAAACTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTG
GGATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTT
GCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATG
TAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGC
TGGGAAAAAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGATTTCAGCAATATCCCCACATACCTTCT
CAAGGATGTAAATGAAGACCCTGGAGAAGATGTGGCCCTCCTCTCTGTTAGTTTTGAGGACACTGAAGCCACCCAGGTGTACCCCAAGCT
GTACTTGTCACCTCGAATTGAGCATGCACTTGGAGGCTCCTCAGCTCTTCATATCCCAGCTTTTCCAGGAGGAGGATGTCTCATTGATTA
CGTTCCTCAAGTATGCCACCTGCTCACCAACAAGGTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCTGCTTTTCT
CAGTCACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTGCTGCTGATGTGGAAAGATTTTTGTTTTCT
TGTACACATTGACCTGCCTCTGTTTTTCCCTCGAGACCAGCCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCT
TTACTCCCAGGCCCAAAAAAATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAAAGAGCAAAGGCTTATTTCAAAACCTT
TGTCCCTCAGTTCCAGGAGGCAGCATTTGCCAATGGAAAGCTCTAGGAAACACCAGTCTTGAGAGGTGGCCAGCCAGACTGCCTGTCCAC
ATGCGTGTCAGCACATACAGCCGCTTCCTGGAAGCCGCCTGGAATGTCTTCACGGCAGCGTTTTGCTCACACAGCAGCTTTTGCACGCCC
CAGGCAGCCCCGACTGCTGAAATCCAACTTGAGCTGGCTGGTGGTCCCTGGATCCTAGAGCCCTTCACTTCGGGTTACTCCCTCTTTCTT
GCCTCTATTTCTTAGTTGGAAGAAATAAACTCACAAATTATGGTGCAGTAATTTTCCGGGGAAAGTAAAGCCTCAGGAATGCCCACGCCT

>55003_55003_6_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000379666_BRE_chr2_28152699_ENST00000342045_length(amino acids)=373AA_BP=1
MLLVGGLLAGDGDCPGVVTMFLSAVFFAKSKSNCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQ
NLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLK
DVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLS
HFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKAYFKTFV

--------------------------------------------------------------
>55003_55003_7_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000379666_BRE_chr2_28152699_ENST00000344773_length(transcript)=1688nt_BP=102nt
GCAGTTGTTGTTGGTTGGGGGCCTTTTGGCCGGTGACGGAGACTGCCCAGGTGTGGTCACCATGTTCCTCTCCGCGGTCTTCTTTGCCAA
GAGCAAGTCAAACTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTG
GGATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTT
GCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATG
TAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGC
TGGGAAAAAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGATTTCAGCAATATCCCCACATACCTTCT
CAAGGATGTAAATGAAGACCCTGGAGAAGATGTGGCCCTCCTCTCTGTTAGTTTTGAGGACACTGAAGCCACCCAGGTGTACCCCAAGCT
GTACTTGTCACCTCGAATTGAGCATGCACTTGGAGGCTCCTCAGCTCTTCATATCCCAGCTTTTCCAGGAGGAGGATGTCTCATTGATTA
CGTTCCTCAAGTATGCCACCTGCTCACCAACAAGGTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCTGCTTTTCT
CAGTCACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTGCTGCTGATGTGGAAAGATTTTTGTTTTCT
TGTACACATTGACCTGCCTCTGTTTTTCCCTCGAGACCAGCCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCT
TTACTCCCAGGCCCAAAAAAATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAAAGAGCAAAGGGATGCCAAGGGAGCAG
AGATGCCTGCAGCCCGTGGGAGCAAGTCCTGGCCTTTGCAGTTGCAAAAACTGGCTGCAAGCTGCTCCAGCCCCAGAGGAACTGGCCAAG
CTCCAGAGGGCCTCCTTGGAGGGCCTCAGAGGGAGAGAGAACTGCTCAGTAATTTTGATCACTTTGGGCTTATTTCAAAACCTTTGTCCC
TCAGTTCCAGGAGGCAGCATTTGCCAATGGAAAGCTCTAGGAAACACCAGTCTTGAGAGGTGGCCAGCCAGACTGCCTGTCCACATGCGT
GTCAGCACATACAGCCGCTTCCTGGAAGCCGCCTGGAATGTCTTCACGGCAGCGTTTTGCTCACACAGCAGCTTTTGCACGCCCCAGGCA
GCCCCGACTGCTGAAATCCAACTTGAGCTGGCTGGTGGTCCCTGGATCCTAGAGCCCTTCACTTCGGGTTACTCCCTCTTTCTTGCCTCT
ATTTCTTAGTTGGAAGAAATAAACTCACAAATTATGGTGCAGTAATTTTCCGGGGAAAGTAAAGCCTCAGGAATGCCCACGCCTTTCTTC

>55003_55003_7_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000379666_BRE_chr2_28152699_ENST00000344773_length(amino acids)=405AA_BP=1
MLLVGGLLAGDGDCPGVVTMFLSAVFFAKSKSNCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQ
NLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLK
DVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLS
HFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKGCQGSRD

--------------------------------------------------------------
>55003_55003_8_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000379666_BRE_chr2_28152699_ENST00000361704_length(transcript)=1586nt_BP=102nt
GCAGTTGTTGTTGGTTGGGGGCCTTTTGGCCGGTGACGGAGACTGCCCAGGTGTGGTCACCATGTTCCTCTCCGCGGTCTTCTTTGCCAA
GAGCAAGTCAAACTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTG
GGATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTT
GCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATG
TAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGC
TGGGAAAAAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGATTTCAGCAATATCCCCACATACCTTCT
CAAGGATGTAAATGAAGACCCTGGAGAAGATGTGGCCCTCCTCTCTGTTAGTTTTGAGGACACTGAAGCCACCCAGGTGTACCCCAAGCT
GTACTTGTCACCTCGAATTGAGCATGCACTTGGAGGCTCCTCAGCTCTTCATATCCCAGCTTTTCCAGGAGGAGGATGTCTCATTGATTA
CGTTCCTCAAGTATGCCACCTGCTCACCAACAAGGTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCTGCTTTTCT
CAGTCACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTGCTGCTGATGTGGAAAGATTTTTGTTTTCT
TGTACACATTGACCTGCCTCTGTTTTTCCCTCGAGACCAGCCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCT
TTACTCCCAGGCCCAAAAAAATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAAAGAGCAAAAAGAGAGAGCAACAGAGA
TGGGGAGGAATCCAGCTCTGCCTGACATCCAGGCATCCTCTCCAAATTGCATAGGGCTTATTTCAAAACCTTTGTCCCTCAGTTCCAGGA
GGCAGCATTTGCCAATGGAAAGCTCTAGGAAACACCAGTCTTGAGAGGTGGCCAGCCAGACTGCCTGTCCACATGCGTGTCAGCACATAC
AGCCGCTTCCTGGAAGCCGCCTGGAATGTCTTCACGGCAGCGTTTTGCTCACACAGCAGCTTTTGCACGCCCCAGGCAGCCCCGACTGCT
GAAATCCAACTTGAGCTGGCTGGTGGTCCCTGGATCCTAGAGCCCTTCACTTCGGGTTACTCCCTCTTTCTTGCCTCTATTTCTTAGTTG
GAAGAAATAAACTCACAAATTATGGTGCAGTAATTTTCCGGGGAAAGTAAAGCCTCAGGAATGCCCACGCCTTTCTTCCAAAGCCTTTGT

>55003_55003_8_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000379666_BRE_chr2_28152699_ENST00000361704_length(amino acids)=366AA_BP=1
MLLVGGLLAGDGDCPGVVTMFLSAVFFAKSKSNCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQ
NLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLK
DVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLS
HFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKRESNRDG

--------------------------------------------------------------
>55003_55003_9_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000379666_BRE_chr2_28152699_ENST00000379624_length(transcript)=1514nt_BP=102nt
GCAGTTGTTGTTGGTTGGGGGCCTTTTGGCCGGTGACGGAGACTGCCCAGGTGTGGTCACCATGTTCCTCTCCGCGGTCTTCTTTGCCAA
GAGCAAGTCAAACTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTG
GGATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTT
GCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATG
TAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGC
TGGGAAAAAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGATTTCAGCAATATCCCCACATACCTTCT
CAAGGATGTAAATGAAGACCCTGGAGAAGATGTGGCCCTCCTCTCTGTTAGTTTTGAGGACACTGAAGCCACCCAGGTGTACCCCAAGCT
GTACTTGTCACCTCGAATTGAGCATGCACTTGGAGGCTCCTCAGCTCTTCATATCCCAGCTTTTCCAGGAGGAGGATGTCTCATTGATTA
CGTTCCTCAAGTATGCCACCTGCTCACCAACAAGGTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCTGCTTTTCT
CAGTCACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTGCTGCTGATGTGGAAAGATTTTTGTTTTCT
TGTACACATTGACCTGCCTCTGTTTTTCCCTCGAGACCAGCCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCT
TTACTCCCAGGCCCAAAAAAATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAAAGAGCAAAGGCTTATTTCAAAACCTT
TGTCCCTCAGTTCCAGGAGGCAGCATTTGCCAATGGAAAGCTCTAGGAAACACCAGTCTTGAGAGGTGGCCAGCCAGACTGCCTGTCCAC
ATGCGTGTCAGCACATACAGCCGCTTCCTGGAAGCCGCCTGGAATGTCTTCACGGCAGCGTTTTGCTCACACAGCAGCTTTTGCACGCCC
CAGGCAGCCCCGACTGCTGAAATCCAACTTGAGCTGGCTGGTGGTCCCTGGATCCTAGAGCCCTTCACTTCGGGTTACTCCCTCTTTCTT
GCCTCTATTTCTTAGTTGGAAGAAATAAACTCACAAATTATGGTGCAGTAATTTTCCGGGGAAAGTAAAGCCTCAGGAATGCCCACGCCT

>55003_55003_9_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000379666_BRE_chr2_28152699_ENST00000379624_length(amino acids)=373AA_BP=1
MLLVGGLLAGDGDCPGVVTMFLSAVFFAKSKSNCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQ
NLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLK
DVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLS
HFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKAYFKTFV

--------------------------------------------------------------
>55003_55003_10_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000379666_BRE_chr2_28152699_ENST00000379632_length(transcript)=1586nt_BP=102nt
GCAGTTGTTGTTGGTTGGGGGCCTTTTGGCCGGTGACGGAGACTGCCCAGGTGTGGTCACCATGTTCCTCTCCGCGGTCTTCTTTGCCAA
GAGCAAGTCAAACTGCACATCATTGACTCCTGGGCCCAACTGTGACCGATTTAAACTGCACATACCATATGCTGGAGAGACATTAAAGTG
GGATATCATTTTCAATGCCCAATACCCAGAACTGCCTCCCGATTTTATCTTTGGAGAAGATGCTGAATTCCTGCCAGACCCCTCAGCTTT
GCAGAATCTTGCCTCCTGGAATCCTTCAAATCCTGAATGTCTCTTACTTGTGGTGAAGGAACTTGTGCAACAATATCACCAATTCCAATG
TAGCCGCCTCCGGGAGAGCTCCCGCCTCATGTTTGAATACCAGACATTACTGGAGGAGCCACAGTATGGAGAGAACATGGAAATTTATGC
TGGGAAAAAAAACAACTGGACTGGTGAATTTTCAGCTCGTTTCCTTTTGAAGCTGCCCGTAGATTTCAGCAATATCCCCACATACCTTCT
CAAGGATGTAAATGAAGACCCTGGAGAAGATGTGGCCCTCCTCTCTGTTAGTTTTGAGGACACTGAAGCCACCCAGGTGTACCCCAAGCT
GTACTTGTCACCTCGAATTGAGCATGCACTTGGAGGCTCCTCAGCTCTTCATATCCCAGCTTTTCCAGGAGGAGGATGTCTCATTGATTA
CGTTCCTCAAGTATGCCACCTGCTCACCAACAAGGTGCAGTACGTGATTCAAGGGTATCACAAAAGAAGAGAGTATATTGCTGCTTTTCT
CAGTCACTTTGGCACAGGTGTCGTGGAATATGATGCAGAAGGCTTTACAAAACTCACTCTGCTGCTGATGTGGAAAGATTTTTGTTTTCT
TGTACACATTGACCTGCCTCTGTTTTTCCCTCGAGACCAGCCAACTCTCACATTTCAGTCCGTTTATCACTTTACCAACAGTGGACAGCT
TTACTCCCAGGCCCAAAAAAATTATCCGTACAGCCCCAGATGGGATGGAAATGAAATGGCCAAAAGAGCAAAAAGAGAGAGCAACAGAGA
TGGGGAGGAATCCAGCTCTGCCTGACATCCAGGCATCCTCTCCAAATTGCATAGGGCTTATTTCAAAACCTTTGTCCCTCAGTTCCAGGA
GGCAGCATTTGCCAATGGAAAGCTCTAGGAAACACCAGTCTTGAGAGGTGGCCAGCCAGACTGCCTGTCCACATGCGTGTCAGCACATAC
AGCCGCTTCCTGGAAGCCGCCTGGAATGTCTTCACGGCAGCGTTTTGCTCACACAGCAGCTTTTGCACGCCCCAGGCAGCCCCGACTGCT
GAAATCCAACTTGAGCTGGCTGGTGGTCCCTGGATCCTAGAGCCCTTCACTTCGGGTTACTCCCTCTTTCTTGCCTCTATTTCTTAGTTG
GAAGAAATAAACTCACAAATTATGGTGCAGTAATTTTCCGGGGAAAGTAAAGCCTCAGGAATGCCCACGCCTTTCTTCCAAAGCCTTTGT

>55003_55003_10_MRPL33-BRE_MRPL33_chr2_27995559_ENST00000379666_BRE_chr2_28152699_ENST00000379632_length(amino acids)=366AA_BP=1
MLLVGGLLAGDGDCPGVVTMFLSAVFFAKSKSNCTSLTPGPNCDRFKLHIPYAGETLKWDIIFNAQYPELPPDFIFGEDAEFLPDPSALQ
NLASWNPSNPECLLLVVKELVQQYHQFQCSRLRESSRLMFEYQTLLEEPQYGENMEIYAGKKNNWTGEFSARFLLKLPVDFSNIPTYLLK
DVNEDPGEDVALLSVSFEDTEATQVYPKLYLSPRIEHALGGSSALHIPAFPGGGCLIDYVPQVCHLLTNKVQYVIQGYHKRREYIAAFLS
HFGTGVVEYDAEGFTKLTLLLMWKDFCFLVHIDLPLFFPRDQPTLTFQSVYHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKRESNRDG

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for MRPL33-BRE

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for MRPL33-BRE

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for MRPL33-BRE

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source