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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:MRPL48-DTX4 (FusionGDB2 ID:55064)

Fusion Gene Summary for MRPL48-DTX4

Fusion gene summary

Fusion gene information	Fusion gene name: MRPL48-DTX4
	Fusion gene ID: 55064
		Hgene	Tgene
	Gene symbol	MRPL48	DTX4
	Gene ID	51642	23220
	Gene name	mitochondrial ribosomal protein L48	deltex E3 ubiquitin ligase 4
	Synonyms	CGI-118\|HSPC290\|L48MT\|MRP-L48	RNF155
	Cytomap	11q13.4	11q12.1
	Type of gene	protein-coding	protein-coding
	Description	39S ribosomal protein L48, mitochondrialmitochondrial large ribosomal subunit protein mL48	E3 ubiquitin-protein ligase DTX4RING finger protein 155RING-type E3 ubiquitin transferase DTX4deltex 4 homologdeltex 4, E3 ubiquitin ligasedeltex homolog 4deltex4protein deltex-4
	Modification date	20200313	20200313
	UniProtAcc	Q96GC5	Q9Y2E6
	Ensembl transtripts involved in fusion gene	ENST00000310614, ENST00000535529, ENST00000542303, ENST00000398483, ENST00000411840, ENST00000314282,	ENST00000531902, ENST00000227451, ENST00000532982,
Fusion gene scores	* DoF score	16 X 9 X 9=1296	4 X 4 X 3=48
	# samples	19	5
	** MAII score	log2(19/1296*10)=-2.76999439455368 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/48*10)=0.0588936890535686 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: MRPL48 [Title/Abstract] AND DTX4 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	MRPL48(73536841)-DTX4(58972149), # samples:17
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across MRPL48 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across DTX4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-A8-A06O-01A	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A076-01A	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A07P-01A	MRPL48	chr11	73536841	-	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A07P-01A	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A086-01A	MRPL48	chr11	73536841	-	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A086-01A	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A08J-01A	MRPL48	chr11	73536841	-	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A08J-01A	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A092-01A	MRPL48	chr11	73536841	-	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A092-01A	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A093-01A	MRPL48	chr11	73536841	-	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A093-01A	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
ChimerDB4	BRCA	TCGA-A8-A093	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+

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Fusion Gene ORF analysis for MRPL48-DTX4

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000310614	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
5CDS-intron	ENST00000310614	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
5CDS-intron	ENST00000535529	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
5CDS-intron	ENST00000535529	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
5CDS-intron	ENST00000542303	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
5CDS-intron	ENST00000542303	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
5UTR-3CDS	ENST00000398483	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
5UTR-3CDS	ENST00000398483	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
5UTR-3CDS	ENST00000398483	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
5UTR-3CDS	ENST00000398483	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
5UTR-3CDS	ENST00000411840	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
5UTR-3CDS	ENST00000411840	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
5UTR-3CDS	ENST00000411840	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
5UTR-3CDS	ENST00000411840	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
5UTR-intron	ENST00000398483	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
5UTR-intron	ENST00000398483	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
5UTR-intron	ENST00000411840	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
5UTR-intron	ENST00000411840	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
In-frame	ENST00000310614	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
In-frame	ENST00000310614	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
In-frame	ENST00000310614	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
In-frame	ENST00000310614	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
In-frame	ENST00000535529	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
In-frame	ENST00000535529	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
In-frame	ENST00000535529	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
In-frame	ENST00000535529	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
In-frame	ENST00000542303	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
In-frame	ENST00000542303	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
In-frame	ENST00000542303	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
In-frame	ENST00000542303	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
intron-3CDS	ENST00000314282	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
intron-3CDS	ENST00000314282	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
intron-3CDS	ENST00000314282	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
intron-3CDS	ENST00000314282	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+
intron-intron	ENST00000314282	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+
intron-intron	ENST00000314282	ENST00000531902	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000310614	MRPL48	chr11	73536841	+	ENST00000532982	DTX4	chr11	58972149	+	1091	857	509	1090	194
ENST00000310614	MRPL48	chr11	73536841	+	ENST00000227451	DTX4	chr11	58972149	+	4769	857	509	1090	193
ENST00000535529	MRPL48	chr11	73536841	+	ENST00000532982	DTX4	chr11	58972149	+	593	359	212	592	127
ENST00000535529	MRPL48	chr11	73536841	+	ENST00000227451	DTX4	chr11	58972149	+	4271	359	623	1120	165
ENST00000542303	MRPL48	chr11	73536841	+	ENST00000532982	DTX4	chr11	58972149	+	498	264	63	497	144
ENST00000542303	MRPL48	chr11	73536841	+	ENST00000227451	DTX4	chr11	58972149	+	4176	264	528	1025	165
ENST00000310614	MRPL48	chr11	73536841	+	ENST00000532982	DTX4	chr11	58972148	+	1091	857	509	1090	194
ENST00000310614	MRPL48	chr11	73536841	+	ENST00000227451	DTX4	chr11	58972148	+	4769	857	509	1090	193
ENST00000535529	MRPL48	chr11	73536841	+	ENST00000532982	DTX4	chr11	58972148	+	593	359	212	592	127
ENST00000535529	MRPL48	chr11	73536841	+	ENST00000227451	DTX4	chr11	58972148	+	4271	359	623	1120	165
ENST00000542303	MRPL48	chr11	73536841	+	ENST00000532982	DTX4	chr11	58972148	+	498	264	63	497	144
ENST00000542303	MRPL48	chr11	73536841	+	ENST00000227451	DTX4	chr11	58972148	+	4176	264	528	1025	165

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000310614	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+	0.01312082	0.98687917
ENST00000310614	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+	0.006963977	0.993036
ENST00000535529	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+	0.011725848	0.9882741
ENST00000535529	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+	0.4215679	0.5784321
ENST00000542303	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+	0.011505155	0.9884948
ENST00000542303	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972149	+	0.4492059	0.5507941
ENST00000310614	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+	0.01312082	0.98687917
ENST00000310614	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+	0.006963977	0.993036
ENST00000535529	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+	0.011725848	0.9882741
ENST00000535529	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+	0.4215679	0.5784321
ENST00000542303	ENST00000532982	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+	0.011505155	0.9884948
ENST00000542303	ENST00000227451	MRPL48	chr11	73536841	+	DTX4	chr11	58972148	+	0.4492059	0.5507941

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Fusion Genomic Features for MRPL48-DTX4

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MRPL48-DTX4

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:73536841/chr11:58972149)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
MRPL48 Q96GC5	DTX4 Q9Y2E6
	FUNCTION: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4. {ECO:0000250, ECO:0000269\|PubMed:22388039}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

MRPL48

chr11:73536841

chr11:58972148

ENST00000310614

69_74

213.0

Compositional bias

Note=Poly-Lys

Hgene

MRPL48

chr11:73536841

chr11:58972149

ENST00000310614

69_74

213.0

Compositional bias

Note=Poly-Lys

Tgene

DTX4

chr11:73536841

chr11:58972148

ENST00000227451

1_78

542

620.0

Domain

WWE 1

Tgene

DTX4

chr11:73536841

chr11:58972148

ENST00000227451

79_155

542

620.0

Domain

WWE 2

Tgene

DTX4

chr11:73536841

chr11:58972148

ENST00000532982

1_78

436

514.0

Domain

WWE 1

Tgene

DTX4

chr11:73536841

chr11:58972148

ENST00000532982

79_155

436

514.0

Domain

WWE 2

Tgene

DTX4

chr11:73536841

chr11:58972149

ENST00000227451

1_78

542

620.0

Domain

WWE 1

Tgene

DTX4

chr11:73536841

chr11:58972149

ENST00000227451

79_155

542

620.0

Domain

WWE 2

Tgene

DTX4

chr11:73536841

chr11:58972149

ENST00000532982

1_78

436

514.0

Domain

WWE 1

Tgene

DTX4

chr11:73536841

chr11:58972149

ENST00000532982

79_155

436

514.0

Domain

WWE 2

Tgene

DTX4

chr11:73536841

chr11:58972148

ENST00000227451

409_468

542

620.0

Zinc finger

RING-type%3B atypical

Tgene

DTX4

chr11:73536841

chr11:58972148

ENST00000532982

409_468

436

514.0

Zinc finger

RING-type%3B atypical

Tgene

DTX4

chr11:73536841

chr11:58972149

ENST00000227451

409_468

542

620.0

Zinc finger

RING-type%3B atypical

Tgene

DTX4

chr11:73536841

chr11:58972149

ENST00000532982

409_468

436

514.0

Zinc finger

RING-type%3B atypical

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Fusion Gene Sequence for MRPL48-DTX4

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>55064_55064_1_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000310614_DTX4_chr11_58972148_ENST00000227451_length(transcript)=4769nt_BP=857nt
AGGCCGAGGCGGGCGGATCACCTGAGGTCGGGAGTTCAAGACCAGCCTGACAAACATGGAGAAACCTCATCTCTAGTAAAAATATAAAAA
TTAGGCGGGCGTGGTGGCGGGCACCTGTAATCCCAGCTACTTGGAGACAGAATTGCTTGAACCCGAGAGGCGGAGGTGGCAGTGAGCTGA
GATCGTGCCACTACACTCCAGCCTGCGCAACAGAGCGAGACTCCGTCTCAAACAAACAAAAAAGTCAGATCTGTGCTAGACGCTGAAAGG
AATTAATCAGACAGGATCTCAGTCTTTTAAGAACTTTCAAATACAGAGAAGAGGTGGTAACAAATCATTAGTGTATAATATTGTAAGCGA
AAAATTAGAATTGTGTGCTAAGTACTGGGGTAACACAGAGATGGTAATTAATTCTTTCTGGAGAAACAGCAGTGAATGTGACAACCTGAG
TGAGGGTGGAAAGCAGGAGAATTTCTAGACTCTGAATTTCAGAAGCTTCCGGAACTAAAATGATGTGGAAGTTGAGTGAGTCTCGGTGGG
ATATTGCTGCTGCACCTGGTCAAGGCCGTTCCTTCAGTGTTTTCAGACGCCCTGGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCAC
AGCTAGAGGCCGCGCAGCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTGTGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTT
CTCTCTTAAGGTTTAGAACTTCAGGAGAGAAGCCCATCTATTCTGTAGGTGGAATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGC
CCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGGTTCTGAAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTT
TTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCTGGAATGAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCA
CTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTGAACTGGCTGCCCAGGGCATCTCTGAGGACAGCACTGCCCAGG
AGAAGGACTGAGGCCAGAAAAGCTTTGAGGTGGGAGGGGCCATGGAGACTGCAGGACAGGAAGTGAGGAGAGTGAGTCAATGTAGAAGAA
GTTGGTGTCCTGCCCTCCCAACTTTCTATCCTCCCCTCCTGCCCTGTGTCCATCCCTCATCCCTCCCAACCACAGTGGGAGCCAGACTGA
ATATAGCGACATCATTCATAAATCTCATCCAACACAAAGGGAGATGGGATGAGGGCCATCCTGGGTCTGTTCCCATGGAGTTTTTGGTGC
TGGGTAGGCAGGAATCCCCTCCCTACCCCACCTCCCAAGTAGGGGCATGGTCAGCACACCTAGGGTATGGGCAGTGCTTAGGCACTCCAT
ATCCTGGCTTTGGGAAGCCGGGGTTTCTTGCCTCAGCCGGCTTCTTGCTACTTCCACTCTGCTTTGAGACTGGAGTTTCTGCTATTCTCC
CTCTGCTGGAGGCAGGGAGCTCTCACTGTGCAAGGTTGGGGGGTGGGCAAAGGGGTGAATCACTAAACTGCTGTGACATCAGAAACTGAT
GCCTTGGTGTAGAGCAAGGAAGCACTTCTTCCCAAGAGGGTCGGAGAAGGAAAAGCCTCTGGGAGCACATTCTGCTGTCATCACAGTCCT
TGGCTTCTCTGGGCCCTCCTCTCCTCCTCACAGCTCTCACCTGTCCAAAGAGGCATCTGGTTCTCTCATGTGGATGGATGGACTCTGGGG
TTCCTCTTTGGAGTGGCATCCCATGATGCTGTTTCTAGACCCTCTCTGATCAAACCAGAGCCTGCATCCCACTGAGCATCTGAACTGTCC
TCAGGGAGAGGAGCCCACAGCCTTCTTCCCAACTCATTCTAGACCAGCTCAAAGATTCCATGAGTTTCATCGAGTCACTGTGAGTGGAGC
CCATGCTGGGCTCTGTGCCCTCTGTGTCTGTGCATGCGCGTGTGTGTGTGGGCGTGTGTGCATTGCTGGGCCAGCTTGAAGGGAAGGCCC
GTCATGTCCCTGCACTCTGTTTTGCAAGATGCCAAACCCCAGTTCTGATGGGGCTCCAACAGCCAGGCTGTGGTCCTTTGACGTTCCTCA
CCTGTTGCCAACCTATCCCGTAGTGAACTGAAACCCCAATGAAGACAGAACTGTGCCTGGGGAGATGCAATGAGGTGAGGGCTGAACTCA
TCCTTTTATATTTCTTTTCAAGATTGGATCAGAGCTCATCTCCATCCAGTCTTGTTTCTATGAAGGCTTCAATCTGTTTCCATGCAAATT
TGCTAATCAGAGCCCAGAGCTGCTGGGTCCCTCATCTCCCTCATCTATTATAGATTGACTTACAGCAGGGAGAGAATCTCTTTAGCTCAT
TCCTAATGGAGTTGGGATCACAATATGGTCTGGTCCAATCTGCATCTTGTTGTGTCCCAAGACCCTATCTCCTCCCCAACATTCTTATTG
CCTTTGGCTCCCAGTAAGGAACGAATTGGGGGCCAGGGAGGAGAACAGGGGGGATCAAGAAGGGAAACCCAATTCCCCCTTTGAAAGTGG
GTTCTTTGAACTATGTGTTTGGGGGAAGTTCCTCTGGATACTAATTTGAATTTATATACCTCATGTTTTGGGGGTTTGACGTATATATAT
ATATATATATATGCATATATATTTCATAATATTTGGAAGGTTTTTGATGCTAGAAAAATGGAAACAAGAGAACCTTCAAAAATGGTACTT
AGATGGGAACTGGAGGCCAATCTTTCATAAAGCCAGCCCCATAGCTGCTTGCTGTTAGGCCTCCAGCCATTTTGACATTGGGGTGGATAG
TCGATTCACCTGCCTGTCAGTCGATTCACCTGCCTGTCACCCAGTTCTGTGGATGTGCTGGTGCTGAGCCTTTGCTCTCTTTCCAAATGG
TTACAGGGATGTTGATCAGCTCCACCAGAGGGAGCTCTGATGGGAGGAATTGCTCTGCCATCCTTGTCCCTGTGTCTCCTGTCGGCAGGC
AGCCATTGTATCTCACCAGCAGACCAGGAGACTGGTCCCAAGGTTACTGCACCACAGGGCAATTTCCTGCCATAGTTAGGAAGGAAACAC
CTGAACTAAATGGAAGAGACATCCCTGCGGTGTTTAATATCACACCCATGCCCTTTGTCAGGTTACCATGTACAGAGATTACTTGGAGAG
CCTCATGCCGTCTCTACCTTCGCACACTGGTCAAGTATCTGCTGAGCTTCTTGGCCGCAAGGATGCAGAAATAGGCTGAGGGTCCATGGG
AAGAAAGACACAATGAGGCAGTAGGAGGTGGGGAAGAAAAGAAGACAGACTTTCAAAATGGAATTAGGCACTGGGGAGAGATCAGTTTCC
CCACATCAGGGAGAAGAAGGTATAGGTGGGGAAGGGGGTGGCCAGGAGCAGAAGGAAGAAGACTCAAGATGGAAAGGGAGCCGCTGTGCC
TGTGGCAATACCACTTGGAGAGGTCGACTTCATACCTTCAAGCCTTTTCCCCTGGGCTTTTGATTGTGTCTGTGCCCCCTTTCTTGTCCT
CTCTGCAGATGCCCAGTAGGGGCTACCTCATCCTCGTGCTGTTCTTGTGTGGCTTTCTGGGCAGTAGGGATCTTGAATTTCCTTTCTAAC
ACTGTGCCCGGCAAGGCGGGGAGCATTCCTCTGCCCTTTGTCTTGTGCCAACCTGGAAAGGTGCAGTCTAGATTTCAGTGAGAACCCTGC
CAGCTGAGCCCTGTGCATCTACTACCTTGACACAGAGTGTTTTCCCACTAGAAGCTCTGCTCTGCTCTCCTGGCCCAAGTAGGGGATTCC
ATGCCTTCCCTTTCATGGTCTTAGCACCAGCAGCCTAGTTTCTCCCTTCCAGAGTCTCCAGGGATGACAAATTGGATTGGAGACAAACCT
CGTCAGATGCTCATCCCCTAAAAGGTTAATTGTGTATTTGTGGCTGCGTGTGCCTTTGTGTTTTCATTCTCTTCCCATTTTTGTACATTT
TGGTCTTCTCTGTGGTTTTATACTTGGTCAAAAGTACTCGTCTTGGTATTGCACTGTTGTGTGCATGAGAAAACTGGGGGAAGGCTCACT
GGTACAAGAAAGGACCCCTGACCCCTTTCCTTCTCTGTGGTCCCCGGCATTAGATTGGGGGTTCTGGGAGAGGCAGGTGAATGTCCTAAG
TGAATTGTTCTGTTTGTAACTGGAATGTTTTTGAAGTCTTTGGTGTTGCTCCGTGAAAGGACATCGCCACCTGGTGCTCATGAGGTGTCT
TTGCAGAACAATAAATGGCAAATGAACAACCACAAAATTGTTACTCTTGTTGGCCTTCTGCTGTTTGTAGATTAGTGCACCTATCTGTGA
GGGATTTGGGTTACCTCCCTGAGTCTGTAAGCAACCACAAGCCCTGCCACTGGGTGGGGGAAGTCCCTCCCCAACCACTTAAAAACAAAT
TTTCCACATATTACCCACCCACACATTTGACCTGGCTAGACTTTGTTTGCCTAAAGGAACAGACCACATTGCTGGGAAAATGAGTAAGTG
AACGTGTGGGAGAAAAACACTTTTAGAATCACGAATATTCACTTTTAAAGGTCTCTTTGCCTGGCTGCAATATAGTGTGTGTTTAAATTA

>55064_55064_1_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000310614_DTX4_chr11_58972148_ENST00000227451_length(amino acids)=193AA_BP=116
MMWKLSESRWDIAAAPGQGRSFSVFRRPGNAAAGSGLRFAQLEAAQQQRMSGTLEKVLCLRNNTIFKQAFSLLRFRTSGEKPIYSVGGIL
LSISRPYKTKPTHGIGKYKHLIKAEEVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAA

--------------------------------------------------------------
>55064_55064_2_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000310614_DTX4_chr11_58972148_ENST00000532982_length(transcript)=1091nt_BP=857nt
AGGCCGAGGCGGGCGGATCACCTGAGGTCGGGAGTTCAAGACCAGCCTGACAAACATGGAGAAACCTCATCTCTAGTAAAAATATAAAAA
TTAGGCGGGCGTGGTGGCGGGCACCTGTAATCCCAGCTACTTGGAGACAGAATTGCTTGAACCCGAGAGGCGGAGGTGGCAGTGAGCTGA
GATCGTGCCACTACACTCCAGCCTGCGCAACAGAGCGAGACTCCGTCTCAAACAAACAAAAAAGTCAGATCTGTGCTAGACGCTGAAAGG
AATTAATCAGACAGGATCTCAGTCTTTTAAGAACTTTCAAATACAGAGAAGAGGTGGTAACAAATCATTAGTGTATAATATTGTAAGCGA
AAAATTAGAATTGTGTGCTAAGTACTGGGGTAACACAGAGATGGTAATTAATTCTTTCTGGAGAAACAGCAGTGAATGTGACAACCTGAG
TGAGGGTGGAAAGCAGGAGAATTTCTAGACTCTGAATTTCAGAAGCTTCCGGAACTAAAATGATGTGGAAGTTGAGTGAGTCTCGGTGGG
ATATTGCTGCTGCACCTGGTCAAGGCCGTTCCTTCAGTGTTTTCAGACGCCCTGGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCAC
AGCTAGAGGCCGCGCAGCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTGTGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTT
CTCTCTTAAGGTTTAGAACTTCAGGAGAGAAGCCCATCTATTCTGTAGGTGGAATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGC
CCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGGTTCTGAAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTT
TTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCTGGAATGAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCA
CTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTGAACTGGCTGCCCAGGGCATCTCTGAGGACAGCACTGCCCAGG

>55064_55064_2_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000310614_DTX4_chr11_58972148_ENST00000532982_length(amino acids)=194AA_BP=116
MMWKLSESRWDIAAAPGQGRSFSVFRRPGNAAAGSGLRFAQLEAAQQQRMSGTLEKVLCLRNNTIFKQAFSLLRFRTSGEKPIYSVGGIL
LSISRPYKTKPTHGIGKYKHLIKAEEVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAA

--------------------------------------------------------------
>55064_55064_3_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000310614_DTX4_chr11_58972149_ENST00000227451_length(transcript)=4769nt_BP=857nt
AGGCCGAGGCGGGCGGATCACCTGAGGTCGGGAGTTCAAGACCAGCCTGACAAACATGGAGAAACCTCATCTCTAGTAAAAATATAAAAA
TTAGGCGGGCGTGGTGGCGGGCACCTGTAATCCCAGCTACTTGGAGACAGAATTGCTTGAACCCGAGAGGCGGAGGTGGCAGTGAGCTGA
GATCGTGCCACTACACTCCAGCCTGCGCAACAGAGCGAGACTCCGTCTCAAACAAACAAAAAAGTCAGATCTGTGCTAGACGCTGAAAGG
AATTAATCAGACAGGATCTCAGTCTTTTAAGAACTTTCAAATACAGAGAAGAGGTGGTAACAAATCATTAGTGTATAATATTGTAAGCGA
AAAATTAGAATTGTGTGCTAAGTACTGGGGTAACACAGAGATGGTAATTAATTCTTTCTGGAGAAACAGCAGTGAATGTGACAACCTGAG
TGAGGGTGGAAAGCAGGAGAATTTCTAGACTCTGAATTTCAGAAGCTTCCGGAACTAAAATGATGTGGAAGTTGAGTGAGTCTCGGTGGG
ATATTGCTGCTGCACCTGGTCAAGGCCGTTCCTTCAGTGTTTTCAGACGCCCTGGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCAC
AGCTAGAGGCCGCGCAGCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTGTGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTT
CTCTCTTAAGGTTTAGAACTTCAGGAGAGAAGCCCATCTATTCTGTAGGTGGAATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGC
CCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGGTTCTGAAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTT
TTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCTGGAATGAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCA
CTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTGAACTGGCTGCCCAGGGCATCTCTGAGGACAGCACTGCCCAGG
AGAAGGACTGAGGCCAGAAAAGCTTTGAGGTGGGAGGGGCCATGGAGACTGCAGGACAGGAAGTGAGGAGAGTGAGTCAATGTAGAAGAA
GTTGGTGTCCTGCCCTCCCAACTTTCTATCCTCCCCTCCTGCCCTGTGTCCATCCCTCATCCCTCCCAACCACAGTGGGAGCCAGACTGA
ATATAGCGACATCATTCATAAATCTCATCCAACACAAAGGGAGATGGGATGAGGGCCATCCTGGGTCTGTTCCCATGGAGTTTTTGGTGC
TGGGTAGGCAGGAATCCCCTCCCTACCCCACCTCCCAAGTAGGGGCATGGTCAGCACACCTAGGGTATGGGCAGTGCTTAGGCACTCCAT
ATCCTGGCTTTGGGAAGCCGGGGTTTCTTGCCTCAGCCGGCTTCTTGCTACTTCCACTCTGCTTTGAGACTGGAGTTTCTGCTATTCTCC
CTCTGCTGGAGGCAGGGAGCTCTCACTGTGCAAGGTTGGGGGGTGGGCAAAGGGGTGAATCACTAAACTGCTGTGACATCAGAAACTGAT
GCCTTGGTGTAGAGCAAGGAAGCACTTCTTCCCAAGAGGGTCGGAGAAGGAAAAGCCTCTGGGAGCACATTCTGCTGTCATCACAGTCCT
TGGCTTCTCTGGGCCCTCCTCTCCTCCTCACAGCTCTCACCTGTCCAAAGAGGCATCTGGTTCTCTCATGTGGATGGATGGACTCTGGGG
TTCCTCTTTGGAGTGGCATCCCATGATGCTGTTTCTAGACCCTCTCTGATCAAACCAGAGCCTGCATCCCACTGAGCATCTGAACTGTCC
TCAGGGAGAGGAGCCCACAGCCTTCTTCCCAACTCATTCTAGACCAGCTCAAAGATTCCATGAGTTTCATCGAGTCACTGTGAGTGGAGC
CCATGCTGGGCTCTGTGCCCTCTGTGTCTGTGCATGCGCGTGTGTGTGTGGGCGTGTGTGCATTGCTGGGCCAGCTTGAAGGGAAGGCCC
GTCATGTCCCTGCACTCTGTTTTGCAAGATGCCAAACCCCAGTTCTGATGGGGCTCCAACAGCCAGGCTGTGGTCCTTTGACGTTCCTCA
CCTGTTGCCAACCTATCCCGTAGTGAACTGAAACCCCAATGAAGACAGAACTGTGCCTGGGGAGATGCAATGAGGTGAGGGCTGAACTCA
TCCTTTTATATTTCTTTTCAAGATTGGATCAGAGCTCATCTCCATCCAGTCTTGTTTCTATGAAGGCTTCAATCTGTTTCCATGCAAATT
TGCTAATCAGAGCCCAGAGCTGCTGGGTCCCTCATCTCCCTCATCTATTATAGATTGACTTACAGCAGGGAGAGAATCTCTTTAGCTCAT
TCCTAATGGAGTTGGGATCACAATATGGTCTGGTCCAATCTGCATCTTGTTGTGTCCCAAGACCCTATCTCCTCCCCAACATTCTTATTG
CCTTTGGCTCCCAGTAAGGAACGAATTGGGGGCCAGGGAGGAGAACAGGGGGGATCAAGAAGGGAAACCCAATTCCCCCTTTGAAAGTGG
GTTCTTTGAACTATGTGTTTGGGGGAAGTTCCTCTGGATACTAATTTGAATTTATATACCTCATGTTTTGGGGGTTTGACGTATATATAT
ATATATATATATGCATATATATTTCATAATATTTGGAAGGTTTTTGATGCTAGAAAAATGGAAACAAGAGAACCTTCAAAAATGGTACTT
AGATGGGAACTGGAGGCCAATCTTTCATAAAGCCAGCCCCATAGCTGCTTGCTGTTAGGCCTCCAGCCATTTTGACATTGGGGTGGATAG
TCGATTCACCTGCCTGTCAGTCGATTCACCTGCCTGTCACCCAGTTCTGTGGATGTGCTGGTGCTGAGCCTTTGCTCTCTTTCCAAATGG
TTACAGGGATGTTGATCAGCTCCACCAGAGGGAGCTCTGATGGGAGGAATTGCTCTGCCATCCTTGTCCCTGTGTCTCCTGTCGGCAGGC
AGCCATTGTATCTCACCAGCAGACCAGGAGACTGGTCCCAAGGTTACTGCACCACAGGGCAATTTCCTGCCATAGTTAGGAAGGAAACAC
CTGAACTAAATGGAAGAGACATCCCTGCGGTGTTTAATATCACACCCATGCCCTTTGTCAGGTTACCATGTACAGAGATTACTTGGAGAG
CCTCATGCCGTCTCTACCTTCGCACACTGGTCAAGTATCTGCTGAGCTTCTTGGCCGCAAGGATGCAGAAATAGGCTGAGGGTCCATGGG
AAGAAAGACACAATGAGGCAGTAGGAGGTGGGGAAGAAAAGAAGACAGACTTTCAAAATGGAATTAGGCACTGGGGAGAGATCAGTTTCC
CCACATCAGGGAGAAGAAGGTATAGGTGGGGAAGGGGGTGGCCAGGAGCAGAAGGAAGAAGACTCAAGATGGAAAGGGAGCCGCTGTGCC
TGTGGCAATACCACTTGGAGAGGTCGACTTCATACCTTCAAGCCTTTTCCCCTGGGCTTTTGATTGTGTCTGTGCCCCCTTTCTTGTCCT
CTCTGCAGATGCCCAGTAGGGGCTACCTCATCCTCGTGCTGTTCTTGTGTGGCTTTCTGGGCAGTAGGGATCTTGAATTTCCTTTCTAAC
ACTGTGCCCGGCAAGGCGGGGAGCATTCCTCTGCCCTTTGTCTTGTGCCAACCTGGAAAGGTGCAGTCTAGATTTCAGTGAGAACCCTGC
CAGCTGAGCCCTGTGCATCTACTACCTTGACACAGAGTGTTTTCCCACTAGAAGCTCTGCTCTGCTCTCCTGGCCCAAGTAGGGGATTCC
ATGCCTTCCCTTTCATGGTCTTAGCACCAGCAGCCTAGTTTCTCCCTTCCAGAGTCTCCAGGGATGACAAATTGGATTGGAGACAAACCT
CGTCAGATGCTCATCCCCTAAAAGGTTAATTGTGTATTTGTGGCTGCGTGTGCCTTTGTGTTTTCATTCTCTTCCCATTTTTGTACATTT
TGGTCTTCTCTGTGGTTTTATACTTGGTCAAAAGTACTCGTCTTGGTATTGCACTGTTGTGTGCATGAGAAAACTGGGGGAAGGCTCACT
GGTACAAGAAAGGACCCCTGACCCCTTTCCTTCTCTGTGGTCCCCGGCATTAGATTGGGGGTTCTGGGAGAGGCAGGTGAATGTCCTAAG
TGAATTGTTCTGTTTGTAACTGGAATGTTTTTGAAGTCTTTGGTGTTGCTCCGTGAAAGGACATCGCCACCTGGTGCTCATGAGGTGTCT
TTGCAGAACAATAAATGGCAAATGAACAACCACAAAATTGTTACTCTTGTTGGCCTTCTGCTGTTTGTAGATTAGTGCACCTATCTGTGA
GGGATTTGGGTTACCTCCCTGAGTCTGTAAGCAACCACAAGCCCTGCCACTGGGTGGGGGAAGTCCCTCCCCAACCACTTAAAAACAAAT
TTTCCACATATTACCCACCCACACATTTGACCTGGCTAGACTTTGTTTGCCTAAAGGAACAGACCACATTGCTGGGAAAATGAGTAAGTG
AACGTGTGGGAGAAAAACACTTTTAGAATCACGAATATTCACTTTTAAAGGTCTCTTTGCCTGGCTGCAATATAGTGTGTGTTTAAATTA

>55064_55064_3_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000310614_DTX4_chr11_58972149_ENST00000227451_length(amino acids)=193AA_BP=116
MMWKLSESRWDIAAAPGQGRSFSVFRRPGNAAAGSGLRFAQLEAAQQQRMSGTLEKVLCLRNNTIFKQAFSLLRFRTSGEKPIYSVGGIL
LSISRPYKTKPTHGIGKYKHLIKAEEVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAA

--------------------------------------------------------------
>55064_55064_4_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000310614_DTX4_chr11_58972149_ENST00000532982_length(transcript)=1091nt_BP=857nt
AGGCCGAGGCGGGCGGATCACCTGAGGTCGGGAGTTCAAGACCAGCCTGACAAACATGGAGAAACCTCATCTCTAGTAAAAATATAAAAA
TTAGGCGGGCGTGGTGGCGGGCACCTGTAATCCCAGCTACTTGGAGACAGAATTGCTTGAACCCGAGAGGCGGAGGTGGCAGTGAGCTGA
GATCGTGCCACTACACTCCAGCCTGCGCAACAGAGCGAGACTCCGTCTCAAACAAACAAAAAAGTCAGATCTGTGCTAGACGCTGAAAGG
AATTAATCAGACAGGATCTCAGTCTTTTAAGAACTTTCAAATACAGAGAAGAGGTGGTAACAAATCATTAGTGTATAATATTGTAAGCGA
AAAATTAGAATTGTGTGCTAAGTACTGGGGTAACACAGAGATGGTAATTAATTCTTTCTGGAGAAACAGCAGTGAATGTGACAACCTGAG
TGAGGGTGGAAAGCAGGAGAATTTCTAGACTCTGAATTTCAGAAGCTTCCGGAACTAAAATGATGTGGAAGTTGAGTGAGTCTCGGTGGG
ATATTGCTGCTGCACCTGGTCAAGGCCGTTCCTTCAGTGTTTTCAGACGCCCTGGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCAC
AGCTAGAGGCCGCGCAGCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTGTGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTT
CTCTCTTAAGGTTTAGAACTTCAGGAGAGAAGCCCATCTATTCTGTAGGTGGAATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGC
CCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGGTTCTGAAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTT
TTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCTGGAATGAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCA
CTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTGAACTGGCTGCCCAGGGCATCTCTGAGGACAGCACTGCCCAGG

>55064_55064_4_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000310614_DTX4_chr11_58972149_ENST00000532982_length(amino acids)=194AA_BP=116
MMWKLSESRWDIAAAPGQGRSFSVFRRPGNAAAGSGLRFAQLEAAQQQRMSGTLEKVLCLRNNTIFKQAFSLLRFRTSGEKPIYSVGGIL
LSISRPYKTKPTHGIGKYKHLIKAEEVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNVLAELAA

--------------------------------------------------------------
>55064_55064_5_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000535529_DTX4_chr11_58972148_ENST00000227451_length(transcript)=4271nt_BP=359nt
TGGTCAAGGCCGTTCCTTCAGTGTTTTCAGACGCCCTGGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCACAGCTAGAGGCCGCGCA
GCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTGTGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTTCTCTCTTAAGGTTTAG
AACTTCAGGAGAGAAGCCCATCTATTCTGTAGATGGGACTGTCTAGTTGCAGGAAAACAAGCTCAGGGCTTCCACTGATTCTACATTATG
GTGGAATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGCCCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGG
TTCTGAAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTTTTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCT
GGAATGAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCACTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTG
AACTGGCTGCCCAGGGCATCTCTGAGGACAGCACTGCCCAGGAGAAGGACTGAGGCCAGAAAAGCTTTGAGGTGGGAGGGGCCATGGAGA
CTGCAGGACAGGAAGTGAGGAGAGTGAGTCAATGTAGAAGAAGTTGGTGTCCTGCCCTCCCAACTTTCTATCCTCCCCTCCTGCCCTGTG
TCCATCCCTCATCCCTCCCAACCACAGTGGGAGCCAGACTGAATATAGCGACATCATTCATAAATCTCATCCAACACAAAGGGAGATGGG
ATGAGGGCCATCCTGGGTCTGTTCCCATGGAGTTTTTGGTGCTGGGTAGGCAGGAATCCCCTCCCTACCCCACCTCCCAAGTAGGGGCAT
GGTCAGCACACCTAGGGTATGGGCAGTGCTTAGGCACTCCATATCCTGGCTTTGGGAAGCCGGGGTTTCTTGCCTCAGCCGGCTTCTTGC
TACTTCCACTCTGCTTTGAGACTGGAGTTTCTGCTATTCTCCCTCTGCTGGAGGCAGGGAGCTCTCACTGTGCAAGGTTGGGGGGTGGGC
AAAGGGGTGAATCACTAAACTGCTGTGACATCAGAAACTGATGCCTTGGTGTAGAGCAAGGAAGCACTTCTTCCCAAGAGGGTCGGAGAA
GGAAAAGCCTCTGGGAGCACATTCTGCTGTCATCACAGTCCTTGGCTTCTCTGGGCCCTCCTCTCCTCCTCACAGCTCTCACCTGTCCAA
AGAGGCATCTGGTTCTCTCATGTGGATGGATGGACTCTGGGGTTCCTCTTTGGAGTGGCATCCCATGATGCTGTTTCTAGACCCTCTCTG
ATCAAACCAGAGCCTGCATCCCACTGAGCATCTGAACTGTCCTCAGGGAGAGGAGCCCACAGCCTTCTTCCCAACTCATTCTAGACCAGC
TCAAAGATTCCATGAGTTTCATCGAGTCACTGTGAGTGGAGCCCATGCTGGGCTCTGTGCCCTCTGTGTCTGTGCATGCGCGTGTGTGTG
TGGGCGTGTGTGCATTGCTGGGCCAGCTTGAAGGGAAGGCCCGTCATGTCCCTGCACTCTGTTTTGCAAGATGCCAAACCCCAGTTCTGA
TGGGGCTCCAACAGCCAGGCTGTGGTCCTTTGACGTTCCTCACCTGTTGCCAACCTATCCCGTAGTGAACTGAAACCCCAATGAAGACAG
AACTGTGCCTGGGGAGATGCAATGAGGTGAGGGCTGAACTCATCCTTTTATATTTCTTTTCAAGATTGGATCAGAGCTCATCTCCATCCA
GTCTTGTTTCTATGAAGGCTTCAATCTGTTTCCATGCAAATTTGCTAATCAGAGCCCAGAGCTGCTGGGTCCCTCATCTCCCTCATCTAT
TATAGATTGACTTACAGCAGGGAGAGAATCTCTTTAGCTCATTCCTAATGGAGTTGGGATCACAATATGGTCTGGTCCAATCTGCATCTT
GTTGTGTCCCAAGACCCTATCTCCTCCCCAACATTCTTATTGCCTTTGGCTCCCAGTAAGGAACGAATTGGGGGCCAGGGAGGAGAACAG
GGGGGATCAAGAAGGGAAACCCAATTCCCCCTTTGAAAGTGGGTTCTTTGAACTATGTGTTTGGGGGAAGTTCCTCTGGATACTAATTTG
AATTTATATACCTCATGTTTTGGGGGTTTGACGTATATATATATATATATATATGCATATATATTTCATAATATTTGGAAGGTTTTTGAT
GCTAGAAAAATGGAAACAAGAGAACCTTCAAAAATGGTACTTAGATGGGAACTGGAGGCCAATCTTTCATAAAGCCAGCCCCATAGCTGC
TTGCTGTTAGGCCTCCAGCCATTTTGACATTGGGGTGGATAGTCGATTCACCTGCCTGTCAGTCGATTCACCTGCCTGTCACCCAGTTCT
GTGGATGTGCTGGTGCTGAGCCTTTGCTCTCTTTCCAAATGGTTACAGGGATGTTGATCAGCTCCACCAGAGGGAGCTCTGATGGGAGGA
ATTGCTCTGCCATCCTTGTCCCTGTGTCTCCTGTCGGCAGGCAGCCATTGTATCTCACCAGCAGACCAGGAGACTGGTCCCAAGGTTACT
GCACCACAGGGCAATTTCCTGCCATAGTTAGGAAGGAAACACCTGAACTAAATGGAAGAGACATCCCTGCGGTGTTTAATATCACACCCA
TGCCCTTTGTCAGGTTACCATGTACAGAGATTACTTGGAGAGCCTCATGCCGTCTCTACCTTCGCACACTGGTCAAGTATCTGCTGAGCT
TCTTGGCCGCAAGGATGCAGAAATAGGCTGAGGGTCCATGGGAAGAAAGACACAATGAGGCAGTAGGAGGTGGGGAAGAAAAGAAGACAG
ACTTTCAAAATGGAATTAGGCACTGGGGAGAGATCAGTTTCCCCACATCAGGGAGAAGAAGGTATAGGTGGGGAAGGGGGTGGCCAGGAG
CAGAAGGAAGAAGACTCAAGATGGAAAGGGAGCCGCTGTGCCTGTGGCAATACCACTTGGAGAGGTCGACTTCATACCTTCAAGCCTTTT
CCCCTGGGCTTTTGATTGTGTCTGTGCCCCCTTTCTTGTCCTCTCTGCAGATGCCCAGTAGGGGCTACCTCATCCTCGTGCTGTTCTTGT
GTGGCTTTCTGGGCAGTAGGGATCTTGAATTTCCTTTCTAACACTGTGCCCGGCAAGGCGGGGAGCATTCCTCTGCCCTTTGTCTTGTGC
CAACCTGGAAAGGTGCAGTCTAGATTTCAGTGAGAACCCTGCCAGCTGAGCCCTGTGCATCTACTACCTTGACACAGAGTGTTTTCCCAC
TAGAAGCTCTGCTCTGCTCTCCTGGCCCAAGTAGGGGATTCCATGCCTTCCCTTTCATGGTCTTAGCACCAGCAGCCTAGTTTCTCCCTT
CCAGAGTCTCCAGGGATGACAAATTGGATTGGAGACAAACCTCGTCAGATGCTCATCCCCTAAAAGGTTAATTGTGTATTTGTGGCTGCG
TGTGCCTTTGTGTTTTCATTCTCTTCCCATTTTTGTACATTTTGGTCTTCTCTGTGGTTTTATACTTGGTCAAAAGTACTCGTCTTGGTA
TTGCACTGTTGTGTGCATGAGAAAACTGGGGGAAGGCTCACTGGTACAAGAAAGGACCCCTGACCCCTTTCCTTCTCTGTGGTCCCCGGC
ATTAGATTGGGGGTTCTGGGAGAGGCAGGTGAATGTCCTAAGTGAATTGTTCTGTTTGTAACTGGAATGTTTTTGAAGTCTTTGGTGTTG
CTCCGTGAAAGGACATCGCCACCTGGTGCTCATGAGGTGTCTTTGCAGAACAATAAATGGCAAATGAACAACCACAAAATTGTTACTCTT
GTTGGCCTTCTGCTGTTTGTAGATTAGTGCACCTATCTGTGAGGGATTTGGGTTACCTCCCTGAGTCTGTAAGCAACCACAAGCCCTGCC
ACTGGGTGGGGGAAGTCCCTCCCCAACCACTTAAAAACAAATTTTCCACATATTACCCACCCACACATTTGACCTGGCTAGACTTTGTTT
GCCTAAAGGAACAGACCACATTGCTGGGAAAATGAGTAAGTGAACGTGTGGGAGAAAAACACTTTTAGAATCACGAATATTCACTTTTAA
AGGTCTCTTTGCCTGGCTGCAATATAGTGTGTGTTTAAATTATTTACAGGCTGTTGTTTCTCAAATAAATGTTTAATATTAATCATTCCC

>55064_55064_5_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000535529_DTX4_chr11_58972148_ENST00000227451_length(amino acids)=165AA_BP=
METAGQEVRRVSQCRRSWCPALPTFYPPLLPCVHPSSLPTTVGARLNIATSFINLIQHKGRWDEGHPGSVPMEFLVLGRQESPPYPTSQV

--------------------------------------------------------------
>55064_55064_6_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000535529_DTX4_chr11_58972148_ENST00000532982_length(transcript)=593nt_BP=359nt
TGGTCAAGGCCGTTCCTTCAGTGTTTTCAGACGCCCTGGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCACAGCTAGAGGCCGCGCA
GCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTGTGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTTCTCTCTTAAGGTTTAG
AACTTCAGGAGAGAAGCCCATCTATTCTGTAGATGGGACTGTCTAGTTGCAGGAAAACAAGCTCAGGGCTTCCACTGATTCTACATTATG
GTGGAATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGCCCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGG
TTCTGAAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTTTTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCT
GGAATGAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCACTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTG

>55064_55064_6_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000535529_DTX4_chr11_58972148_ENST00000532982_length(amino acids)=127AA_BP=49
MGLSSCRKTSSGLPLILHYGGILLSISRPYKTKPTHGIGKYKHLIKAEEVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFG

--------------------------------------------------------------
>55064_55064_7_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000535529_DTX4_chr11_58972149_ENST00000227451_length(transcript)=4271nt_BP=359nt
TGGTCAAGGCCGTTCCTTCAGTGTTTTCAGACGCCCTGGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCACAGCTAGAGGCCGCGCA
GCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTGTGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTTCTCTCTTAAGGTTTAG
AACTTCAGGAGAGAAGCCCATCTATTCTGTAGATGGGACTGTCTAGTTGCAGGAAAACAAGCTCAGGGCTTCCACTGATTCTACATTATG
GTGGAATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGCCCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGG
TTCTGAAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTTTTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCT
GGAATGAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCACTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTG
AACTGGCTGCCCAGGGCATCTCTGAGGACAGCACTGCCCAGGAGAAGGACTGAGGCCAGAAAAGCTTTGAGGTGGGAGGGGCCATGGAGA
CTGCAGGACAGGAAGTGAGGAGAGTGAGTCAATGTAGAAGAAGTTGGTGTCCTGCCCTCCCAACTTTCTATCCTCCCCTCCTGCCCTGTG
TCCATCCCTCATCCCTCCCAACCACAGTGGGAGCCAGACTGAATATAGCGACATCATTCATAAATCTCATCCAACACAAAGGGAGATGGG
ATGAGGGCCATCCTGGGTCTGTTCCCATGGAGTTTTTGGTGCTGGGTAGGCAGGAATCCCCTCCCTACCCCACCTCCCAAGTAGGGGCAT
GGTCAGCACACCTAGGGTATGGGCAGTGCTTAGGCACTCCATATCCTGGCTTTGGGAAGCCGGGGTTTCTTGCCTCAGCCGGCTTCTTGC
TACTTCCACTCTGCTTTGAGACTGGAGTTTCTGCTATTCTCCCTCTGCTGGAGGCAGGGAGCTCTCACTGTGCAAGGTTGGGGGGTGGGC
AAAGGGGTGAATCACTAAACTGCTGTGACATCAGAAACTGATGCCTTGGTGTAGAGCAAGGAAGCACTTCTTCCCAAGAGGGTCGGAGAA
GGAAAAGCCTCTGGGAGCACATTCTGCTGTCATCACAGTCCTTGGCTTCTCTGGGCCCTCCTCTCCTCCTCACAGCTCTCACCTGTCCAA
AGAGGCATCTGGTTCTCTCATGTGGATGGATGGACTCTGGGGTTCCTCTTTGGAGTGGCATCCCATGATGCTGTTTCTAGACCCTCTCTG
ATCAAACCAGAGCCTGCATCCCACTGAGCATCTGAACTGTCCTCAGGGAGAGGAGCCCACAGCCTTCTTCCCAACTCATTCTAGACCAGC
TCAAAGATTCCATGAGTTTCATCGAGTCACTGTGAGTGGAGCCCATGCTGGGCTCTGTGCCCTCTGTGTCTGTGCATGCGCGTGTGTGTG
TGGGCGTGTGTGCATTGCTGGGCCAGCTTGAAGGGAAGGCCCGTCATGTCCCTGCACTCTGTTTTGCAAGATGCCAAACCCCAGTTCTGA
TGGGGCTCCAACAGCCAGGCTGTGGTCCTTTGACGTTCCTCACCTGTTGCCAACCTATCCCGTAGTGAACTGAAACCCCAATGAAGACAG
AACTGTGCCTGGGGAGATGCAATGAGGTGAGGGCTGAACTCATCCTTTTATATTTCTTTTCAAGATTGGATCAGAGCTCATCTCCATCCA
GTCTTGTTTCTATGAAGGCTTCAATCTGTTTCCATGCAAATTTGCTAATCAGAGCCCAGAGCTGCTGGGTCCCTCATCTCCCTCATCTAT
TATAGATTGACTTACAGCAGGGAGAGAATCTCTTTAGCTCATTCCTAATGGAGTTGGGATCACAATATGGTCTGGTCCAATCTGCATCTT
GTTGTGTCCCAAGACCCTATCTCCTCCCCAACATTCTTATTGCCTTTGGCTCCCAGTAAGGAACGAATTGGGGGCCAGGGAGGAGAACAG
GGGGGATCAAGAAGGGAAACCCAATTCCCCCTTTGAAAGTGGGTTCTTTGAACTATGTGTTTGGGGGAAGTTCCTCTGGATACTAATTTG
AATTTATATACCTCATGTTTTGGGGGTTTGACGTATATATATATATATATATATGCATATATATTTCATAATATTTGGAAGGTTTTTGAT
GCTAGAAAAATGGAAACAAGAGAACCTTCAAAAATGGTACTTAGATGGGAACTGGAGGCCAATCTTTCATAAAGCCAGCCCCATAGCTGC
TTGCTGTTAGGCCTCCAGCCATTTTGACATTGGGGTGGATAGTCGATTCACCTGCCTGTCAGTCGATTCACCTGCCTGTCACCCAGTTCT
GTGGATGTGCTGGTGCTGAGCCTTTGCTCTCTTTCCAAATGGTTACAGGGATGTTGATCAGCTCCACCAGAGGGAGCTCTGATGGGAGGA
ATTGCTCTGCCATCCTTGTCCCTGTGTCTCCTGTCGGCAGGCAGCCATTGTATCTCACCAGCAGACCAGGAGACTGGTCCCAAGGTTACT
GCACCACAGGGCAATTTCCTGCCATAGTTAGGAAGGAAACACCTGAACTAAATGGAAGAGACATCCCTGCGGTGTTTAATATCACACCCA
TGCCCTTTGTCAGGTTACCATGTACAGAGATTACTTGGAGAGCCTCATGCCGTCTCTACCTTCGCACACTGGTCAAGTATCTGCTGAGCT
TCTTGGCCGCAAGGATGCAGAAATAGGCTGAGGGTCCATGGGAAGAAAGACACAATGAGGCAGTAGGAGGTGGGGAAGAAAAGAAGACAG
ACTTTCAAAATGGAATTAGGCACTGGGGAGAGATCAGTTTCCCCACATCAGGGAGAAGAAGGTATAGGTGGGGAAGGGGGTGGCCAGGAG
CAGAAGGAAGAAGACTCAAGATGGAAAGGGAGCCGCTGTGCCTGTGGCAATACCACTTGGAGAGGTCGACTTCATACCTTCAAGCCTTTT
CCCCTGGGCTTTTGATTGTGTCTGTGCCCCCTTTCTTGTCCTCTCTGCAGATGCCCAGTAGGGGCTACCTCATCCTCGTGCTGTTCTTGT
GTGGCTTTCTGGGCAGTAGGGATCTTGAATTTCCTTTCTAACACTGTGCCCGGCAAGGCGGGGAGCATTCCTCTGCCCTTTGTCTTGTGC
CAACCTGGAAAGGTGCAGTCTAGATTTCAGTGAGAACCCTGCCAGCTGAGCCCTGTGCATCTACTACCTTGACACAGAGTGTTTTCCCAC
TAGAAGCTCTGCTCTGCTCTCCTGGCCCAAGTAGGGGATTCCATGCCTTCCCTTTCATGGTCTTAGCACCAGCAGCCTAGTTTCTCCCTT
CCAGAGTCTCCAGGGATGACAAATTGGATTGGAGACAAACCTCGTCAGATGCTCATCCCCTAAAAGGTTAATTGTGTATTTGTGGCTGCG
TGTGCCTTTGTGTTTTCATTCTCTTCCCATTTTTGTACATTTTGGTCTTCTCTGTGGTTTTATACTTGGTCAAAAGTACTCGTCTTGGTA
TTGCACTGTTGTGTGCATGAGAAAACTGGGGGAAGGCTCACTGGTACAAGAAAGGACCCCTGACCCCTTTCCTTCTCTGTGGTCCCCGGC
ATTAGATTGGGGGTTCTGGGAGAGGCAGGTGAATGTCCTAAGTGAATTGTTCTGTTTGTAACTGGAATGTTTTTGAAGTCTTTGGTGTTG
CTCCGTGAAAGGACATCGCCACCTGGTGCTCATGAGGTGTCTTTGCAGAACAATAAATGGCAAATGAACAACCACAAAATTGTTACTCTT
GTTGGCCTTCTGCTGTTTGTAGATTAGTGCACCTATCTGTGAGGGATTTGGGTTACCTCCCTGAGTCTGTAAGCAACCACAAGCCCTGCC
ACTGGGTGGGGGAAGTCCCTCCCCAACCACTTAAAAACAAATTTTCCACATATTACCCACCCACACATTTGACCTGGCTAGACTTTGTTT
GCCTAAAGGAACAGACCACATTGCTGGGAAAATGAGTAAGTGAACGTGTGGGAGAAAAACACTTTTAGAATCACGAATATTCACTTTTAA
AGGTCTCTTTGCCTGGCTGCAATATAGTGTGTGTTTAAATTATTTACAGGCTGTTGTTTCTCAAATAAATGTTTAATATTAATCATTCCC

>55064_55064_7_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000535529_DTX4_chr11_58972149_ENST00000227451_length(amino acids)=165AA_BP=
METAGQEVRRVSQCRRSWCPALPTFYPPLLPCVHPSSLPTTVGARLNIATSFINLIQHKGRWDEGHPGSVPMEFLVLGRQESPPYPTSQV

--------------------------------------------------------------
>55064_55064_8_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000535529_DTX4_chr11_58972149_ENST00000532982_length(transcript)=593nt_BP=359nt
TGGTCAAGGCCGTTCCTTCAGTGTTTTCAGACGCCCTGGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCACAGCTAGAGGCCGCGCA
GCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTGTGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTTCTCTCTTAAGGTTTAG
AACTTCAGGAGAGAAGCCCATCTATTCTGTAGATGGGACTGTCTAGTTGCAGGAAAACAAGCTCAGGGCTTCCACTGATTCTACATTATG
GTGGAATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGCCCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGG
TTCTGAAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTTTTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCT
GGAATGAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCACTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTG

>55064_55064_8_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000535529_DTX4_chr11_58972149_ENST00000532982_length(amino acids)=127AA_BP=49
MGLSSCRKTSSGLPLILHYGGILLSISRPYKTKPTHGIGKYKHLIKAEEVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFG

--------------------------------------------------------------
>55064_55064_9_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000542303_DTX4_chr11_58972148_ENST00000227451_length(transcript)=4176nt_BP=264nt
GGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCACAGCTAGAGGCCGCGCAGCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTG
TGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTTCTCTCTTAAGGTTTAGAACTTCAGGAGAGAAGCCCATCTATTCTGTAGGTGGA
ATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGCCCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGGTTCTG
AAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTTTTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCTGGAAT
GAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCACTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTGAACTG
GCTGCCCAGGGCATCTCTGAGGACAGCACTGCCCAGGAGAAGGACTGAGGCCAGAAAAGCTTTGAGGTGGGAGGGGCCATGGAGACTGCA
GGACAGGAAGTGAGGAGAGTGAGTCAATGTAGAAGAAGTTGGTGTCCTGCCCTCCCAACTTTCTATCCTCCCCTCCTGCCCTGTGTCCAT
CCCTCATCCCTCCCAACCACAGTGGGAGCCAGACTGAATATAGCGACATCATTCATAAATCTCATCCAACACAAAGGGAGATGGGATGAG
GGCCATCCTGGGTCTGTTCCCATGGAGTTTTTGGTGCTGGGTAGGCAGGAATCCCCTCCCTACCCCACCTCCCAAGTAGGGGCATGGTCA
GCACACCTAGGGTATGGGCAGTGCTTAGGCACTCCATATCCTGGCTTTGGGAAGCCGGGGTTTCTTGCCTCAGCCGGCTTCTTGCTACTT
CCACTCTGCTTTGAGACTGGAGTTTCTGCTATTCTCCCTCTGCTGGAGGCAGGGAGCTCTCACTGTGCAAGGTTGGGGGGTGGGCAAAGG
GGTGAATCACTAAACTGCTGTGACATCAGAAACTGATGCCTTGGTGTAGAGCAAGGAAGCACTTCTTCCCAAGAGGGTCGGAGAAGGAAA
AGCCTCTGGGAGCACATTCTGCTGTCATCACAGTCCTTGGCTTCTCTGGGCCCTCCTCTCCTCCTCACAGCTCTCACCTGTCCAAAGAGG
CATCTGGTTCTCTCATGTGGATGGATGGACTCTGGGGTTCCTCTTTGGAGTGGCATCCCATGATGCTGTTTCTAGACCCTCTCTGATCAA
ACCAGAGCCTGCATCCCACTGAGCATCTGAACTGTCCTCAGGGAGAGGAGCCCACAGCCTTCTTCCCAACTCATTCTAGACCAGCTCAAA
GATTCCATGAGTTTCATCGAGTCACTGTGAGTGGAGCCCATGCTGGGCTCTGTGCCCTCTGTGTCTGTGCATGCGCGTGTGTGTGTGGGC
GTGTGTGCATTGCTGGGCCAGCTTGAAGGGAAGGCCCGTCATGTCCCTGCACTCTGTTTTGCAAGATGCCAAACCCCAGTTCTGATGGGG
CTCCAACAGCCAGGCTGTGGTCCTTTGACGTTCCTCACCTGTTGCCAACCTATCCCGTAGTGAACTGAAACCCCAATGAAGACAGAACTG
TGCCTGGGGAGATGCAATGAGGTGAGGGCTGAACTCATCCTTTTATATTTCTTTTCAAGATTGGATCAGAGCTCATCTCCATCCAGTCTT
GTTTCTATGAAGGCTTCAATCTGTTTCCATGCAAATTTGCTAATCAGAGCCCAGAGCTGCTGGGTCCCTCATCTCCCTCATCTATTATAG
ATTGACTTACAGCAGGGAGAGAATCTCTTTAGCTCATTCCTAATGGAGTTGGGATCACAATATGGTCTGGTCCAATCTGCATCTTGTTGT
GTCCCAAGACCCTATCTCCTCCCCAACATTCTTATTGCCTTTGGCTCCCAGTAAGGAACGAATTGGGGGCCAGGGAGGAGAACAGGGGGG
ATCAAGAAGGGAAACCCAATTCCCCCTTTGAAAGTGGGTTCTTTGAACTATGTGTTTGGGGGAAGTTCCTCTGGATACTAATTTGAATTT
ATATACCTCATGTTTTGGGGGTTTGACGTATATATATATATATATATATGCATATATATTTCATAATATTTGGAAGGTTTTTGATGCTAG
AAAAATGGAAACAAGAGAACCTTCAAAAATGGTACTTAGATGGGAACTGGAGGCCAATCTTTCATAAAGCCAGCCCCATAGCTGCTTGCT
GTTAGGCCTCCAGCCATTTTGACATTGGGGTGGATAGTCGATTCACCTGCCTGTCAGTCGATTCACCTGCCTGTCACCCAGTTCTGTGGA
TGTGCTGGTGCTGAGCCTTTGCTCTCTTTCCAAATGGTTACAGGGATGTTGATCAGCTCCACCAGAGGGAGCTCTGATGGGAGGAATTGC
TCTGCCATCCTTGTCCCTGTGTCTCCTGTCGGCAGGCAGCCATTGTATCTCACCAGCAGACCAGGAGACTGGTCCCAAGGTTACTGCACC
ACAGGGCAATTTCCTGCCATAGTTAGGAAGGAAACACCTGAACTAAATGGAAGAGACATCCCTGCGGTGTTTAATATCACACCCATGCCC
TTTGTCAGGTTACCATGTACAGAGATTACTTGGAGAGCCTCATGCCGTCTCTACCTTCGCACACTGGTCAAGTATCTGCTGAGCTTCTTG
GCCGCAAGGATGCAGAAATAGGCTGAGGGTCCATGGGAAGAAAGACACAATGAGGCAGTAGGAGGTGGGGAAGAAAAGAAGACAGACTTT
CAAAATGGAATTAGGCACTGGGGAGAGATCAGTTTCCCCACATCAGGGAGAAGAAGGTATAGGTGGGGAAGGGGGTGGCCAGGAGCAGAA
GGAAGAAGACTCAAGATGGAAAGGGAGCCGCTGTGCCTGTGGCAATACCACTTGGAGAGGTCGACTTCATACCTTCAAGCCTTTTCCCCT
GGGCTTTTGATTGTGTCTGTGCCCCCTTTCTTGTCCTCTCTGCAGATGCCCAGTAGGGGCTACCTCATCCTCGTGCTGTTCTTGTGTGGC
TTTCTGGGCAGTAGGGATCTTGAATTTCCTTTCTAACACTGTGCCCGGCAAGGCGGGGAGCATTCCTCTGCCCTTTGTCTTGTGCCAACC
TGGAAAGGTGCAGTCTAGATTTCAGTGAGAACCCTGCCAGCTGAGCCCTGTGCATCTACTACCTTGACACAGAGTGTTTTCCCACTAGAA
GCTCTGCTCTGCTCTCCTGGCCCAAGTAGGGGATTCCATGCCTTCCCTTTCATGGTCTTAGCACCAGCAGCCTAGTTTCTCCCTTCCAGA
GTCTCCAGGGATGACAAATTGGATTGGAGACAAACCTCGTCAGATGCTCATCCCCTAAAAGGTTAATTGTGTATTTGTGGCTGCGTGTGC
CTTTGTGTTTTCATTCTCTTCCCATTTTTGTACATTTTGGTCTTCTCTGTGGTTTTATACTTGGTCAAAAGTACTCGTCTTGGTATTGCA
CTGTTGTGTGCATGAGAAAACTGGGGGAAGGCTCACTGGTACAAGAAAGGACCCCTGACCCCTTTCCTTCTCTGTGGTCCCCGGCATTAG
ATTGGGGGTTCTGGGAGAGGCAGGTGAATGTCCTAAGTGAATTGTTCTGTTTGTAACTGGAATGTTTTTGAAGTCTTTGGTGTTGCTCCG
TGAAAGGACATCGCCACCTGGTGCTCATGAGGTGTCTTTGCAGAACAATAAATGGCAAATGAACAACCACAAAATTGTTACTCTTGTTGG
CCTTCTGCTGTTTGTAGATTAGTGCACCTATCTGTGAGGGATTTGGGTTACCTCCCTGAGTCTGTAAGCAACCACAAGCCCTGCCACTGG
GTGGGGGAAGTCCCTCCCCAACCACTTAAAAACAAATTTTCCACATATTACCCACCCACACATTTGACCTGGCTAGACTTTGTTTGCCTA
AAGGAACAGACCACATTGCTGGGAAAATGAGTAAGTGAACGTGTGGGAGAAAAACACTTTTAGAATCACGAATATTCACTTTTAAAGGTC
TCTTTGCCTGGCTGCAATATAGTGTGTGTTTAAATTATTTACAGGCTGTTGTTTCTCAAATAAATGTTTAATATTAATCATTCCCAAACT

>55064_55064_9_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000542303_DTX4_chr11_58972148_ENST00000227451_length(amino acids)=165AA_BP=
METAGQEVRRVSQCRRSWCPALPTFYPPLLPCVHPSSLPTTVGARLNIATSFINLIQHKGRWDEGHPGSVPMEFLVLGRQESPPYPTSQV

--------------------------------------------------------------
>55064_55064_10_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000542303_DTX4_chr11_58972148_ENST00000532982_length(transcript)=498nt_BP=264nt
GGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCACAGCTAGAGGCCGCGCAGCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTG
TGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTTCTCTCTTAAGGTTTAGAACTTCAGGAGAGAAGCCCATCTATTCTGTAGGTGGA
ATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGCCCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGGTTCTG
AAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTTTTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCTGGAAT
GAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCACTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTGAACTG

>55064_55064_10_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000542303_DTX4_chr11_58972148_ENST00000532982_length(amino acids)=144AA_BP=67
MSGTLEKVLCLRNNTIFKQAFSLLRFRTSGEKPIYSVGGILLSISRPYKTKPTHGIGKYKHLIKAEEVLKLLLVAWDRRLIFAIGTSSTT

--------------------------------------------------------------
>55064_55064_11_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000542303_DTX4_chr11_58972149_ENST00000227451_length(transcript)=4176nt_BP=264nt
GGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCACAGCTAGAGGCCGCGCAGCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTG
TGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTTCTCTCTTAAGGTTTAGAACTTCAGGAGAGAAGCCCATCTATTCTGTAGGTGGA
ATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGCCCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGGTTCTG
AAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTTTTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCTGGAAT
GAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCACTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTGAACTG
GCTGCCCAGGGCATCTCTGAGGACAGCACTGCCCAGGAGAAGGACTGAGGCCAGAAAAGCTTTGAGGTGGGAGGGGCCATGGAGACTGCA
GGACAGGAAGTGAGGAGAGTGAGTCAATGTAGAAGAAGTTGGTGTCCTGCCCTCCCAACTTTCTATCCTCCCCTCCTGCCCTGTGTCCAT
CCCTCATCCCTCCCAACCACAGTGGGAGCCAGACTGAATATAGCGACATCATTCATAAATCTCATCCAACACAAAGGGAGATGGGATGAG
GGCCATCCTGGGTCTGTTCCCATGGAGTTTTTGGTGCTGGGTAGGCAGGAATCCCCTCCCTACCCCACCTCCCAAGTAGGGGCATGGTCA
GCACACCTAGGGTATGGGCAGTGCTTAGGCACTCCATATCCTGGCTTTGGGAAGCCGGGGTTTCTTGCCTCAGCCGGCTTCTTGCTACTT
CCACTCTGCTTTGAGACTGGAGTTTCTGCTATTCTCCCTCTGCTGGAGGCAGGGAGCTCTCACTGTGCAAGGTTGGGGGGTGGGCAAAGG
GGTGAATCACTAAACTGCTGTGACATCAGAAACTGATGCCTTGGTGTAGAGCAAGGAAGCACTTCTTCCCAAGAGGGTCGGAGAAGGAAA
AGCCTCTGGGAGCACATTCTGCTGTCATCACAGTCCTTGGCTTCTCTGGGCCCTCCTCTCCTCCTCACAGCTCTCACCTGTCCAAAGAGG
CATCTGGTTCTCTCATGTGGATGGATGGACTCTGGGGTTCCTCTTTGGAGTGGCATCCCATGATGCTGTTTCTAGACCCTCTCTGATCAA
ACCAGAGCCTGCATCCCACTGAGCATCTGAACTGTCCTCAGGGAGAGGAGCCCACAGCCTTCTTCCCAACTCATTCTAGACCAGCTCAAA
GATTCCATGAGTTTCATCGAGTCACTGTGAGTGGAGCCCATGCTGGGCTCTGTGCCCTCTGTGTCTGTGCATGCGCGTGTGTGTGTGGGC
GTGTGTGCATTGCTGGGCCAGCTTGAAGGGAAGGCCCGTCATGTCCCTGCACTCTGTTTTGCAAGATGCCAAACCCCAGTTCTGATGGGG
CTCCAACAGCCAGGCTGTGGTCCTTTGACGTTCCTCACCTGTTGCCAACCTATCCCGTAGTGAACTGAAACCCCAATGAAGACAGAACTG
TGCCTGGGGAGATGCAATGAGGTGAGGGCTGAACTCATCCTTTTATATTTCTTTTCAAGATTGGATCAGAGCTCATCTCCATCCAGTCTT
GTTTCTATGAAGGCTTCAATCTGTTTCCATGCAAATTTGCTAATCAGAGCCCAGAGCTGCTGGGTCCCTCATCTCCCTCATCTATTATAG
ATTGACTTACAGCAGGGAGAGAATCTCTTTAGCTCATTCCTAATGGAGTTGGGATCACAATATGGTCTGGTCCAATCTGCATCTTGTTGT
GTCCCAAGACCCTATCTCCTCCCCAACATTCTTATTGCCTTTGGCTCCCAGTAAGGAACGAATTGGGGGCCAGGGAGGAGAACAGGGGGG
ATCAAGAAGGGAAACCCAATTCCCCCTTTGAAAGTGGGTTCTTTGAACTATGTGTTTGGGGGAAGTTCCTCTGGATACTAATTTGAATTT
ATATACCTCATGTTTTGGGGGTTTGACGTATATATATATATATATATATGCATATATATTTCATAATATTTGGAAGGTTTTTGATGCTAG
AAAAATGGAAACAAGAGAACCTTCAAAAATGGTACTTAGATGGGAACTGGAGGCCAATCTTTCATAAAGCCAGCCCCATAGCTGCTTGCT
GTTAGGCCTCCAGCCATTTTGACATTGGGGTGGATAGTCGATTCACCTGCCTGTCAGTCGATTCACCTGCCTGTCACCCAGTTCTGTGGA
TGTGCTGGTGCTGAGCCTTTGCTCTCTTTCCAAATGGTTACAGGGATGTTGATCAGCTCCACCAGAGGGAGCTCTGATGGGAGGAATTGC
TCTGCCATCCTTGTCCCTGTGTCTCCTGTCGGCAGGCAGCCATTGTATCTCACCAGCAGACCAGGAGACTGGTCCCAAGGTTACTGCACC
ACAGGGCAATTTCCTGCCATAGTTAGGAAGGAAACACCTGAACTAAATGGAAGAGACATCCCTGCGGTGTTTAATATCACACCCATGCCC
TTTGTCAGGTTACCATGTACAGAGATTACTTGGAGAGCCTCATGCCGTCTCTACCTTCGCACACTGGTCAAGTATCTGCTGAGCTTCTTG
GCCGCAAGGATGCAGAAATAGGCTGAGGGTCCATGGGAAGAAAGACACAATGAGGCAGTAGGAGGTGGGGAAGAAAAGAAGACAGACTTT
CAAAATGGAATTAGGCACTGGGGAGAGATCAGTTTCCCCACATCAGGGAGAAGAAGGTATAGGTGGGGAAGGGGGTGGCCAGGAGCAGAA
GGAAGAAGACTCAAGATGGAAAGGGAGCCGCTGTGCCTGTGGCAATACCACTTGGAGAGGTCGACTTCATACCTTCAAGCCTTTTCCCCT
GGGCTTTTGATTGTGTCTGTGCCCCCTTTCTTGTCCTCTCTGCAGATGCCCAGTAGGGGCTACCTCATCCTCGTGCTGTTCTTGTGTGGC
TTTCTGGGCAGTAGGGATCTTGAATTTCCTTTCTAACACTGTGCCCGGCAAGGCGGGGAGCATTCCTCTGCCCTTTGTCTTGTGCCAACC
TGGAAAGGTGCAGTCTAGATTTCAGTGAGAACCCTGCCAGCTGAGCCCTGTGCATCTACTACCTTGACACAGAGTGTTTTCCCACTAGAA
GCTCTGCTCTGCTCTCCTGGCCCAAGTAGGGGATTCCATGCCTTCCCTTTCATGGTCTTAGCACCAGCAGCCTAGTTTCTCCCTTCCAGA
GTCTCCAGGGATGACAAATTGGATTGGAGACAAACCTCGTCAGATGCTCATCCCCTAAAAGGTTAATTGTGTATTTGTGGCTGCGTGTGC
CTTTGTGTTTTCATTCTCTTCCCATTTTTGTACATTTTGGTCTTCTCTGTGGTTTTATACTTGGTCAAAAGTACTCGTCTTGGTATTGCA
CTGTTGTGTGCATGAGAAAACTGGGGGAAGGCTCACTGGTACAAGAAAGGACCCCTGACCCCTTTCCTTCTCTGTGGTCCCCGGCATTAG
ATTGGGGGTTCTGGGAGAGGCAGGTGAATGTCCTAAGTGAATTGTTCTGTTTGTAACTGGAATGTTTTTGAAGTCTTTGGTGTTGCTCCG
TGAAAGGACATCGCCACCTGGTGCTCATGAGGTGTCTTTGCAGAACAATAAATGGCAAATGAACAACCACAAAATTGTTACTCTTGTTGG
CCTTCTGCTGTTTGTAGATTAGTGCACCTATCTGTGAGGGATTTGGGTTACCTCCCTGAGTCTGTAAGCAACCACAAGCCCTGCCACTGG
GTGGGGGAAGTCCCTCCCCAACCACTTAAAAACAAATTTTCCACATATTACCCACCCACACATTTGACCTGGCTAGACTTTGTTTGCCTA
AAGGAACAGACCACATTGCTGGGAAAATGAGTAAGTGAACGTGTGGGAGAAAAACACTTTTAGAATCACGAATATTCACTTTTAAAGGTC
TCTTTGCCTGGCTGCAATATAGTGTGTGTTTAAATTATTTACAGGCTGTTGTTTCTCAAATAAATGTTTAATATTAATCATTCCCAAACT

>55064_55064_11_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000542303_DTX4_chr11_58972149_ENST00000227451_length(amino acids)=165AA_BP=
METAGQEVRRVSQCRRSWCPALPTFYPPLLPCVHPSSLPTTVGARLNIATSFINLIQHKGRWDEGHPGSVPMEFLVLGRQESPPYPTSQV

--------------------------------------------------------------
>55064_55064_12_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000542303_DTX4_chr11_58972149_ENST00000532982_length(transcript)=498nt_BP=264nt
GGGAACGCGGCTGCAGGGTCCGGTCTTCGGTTTGCACAGCTAGAGGCCGCGCAGCAGCAAAGGATGAGCGGAACCTTGGAAAAGGTGCTG
TGCCTGAGGAACAATACCATTTTTAAGCAAGCCTTTTCTCTCTTAAGGTTTAGAACTTCAGGAGAGAAGCCCATCTATTCTGTAGGTGGA
ATTCTACTAAGTATCAGTCGGCCCTACAAGACAAAGCCCACCCACGGCATTGGAAAGTACAAGCACTTAATTAAAGCAGAAGAGGTTCTG
AAGCTGCTGCTCGTGGCCTGGGATCGCCGCCTCATTTTTGCCATTGGCACCTCCAGCACCACAGGCGAGTCAGACACCGTCATCTGGAAT
GAGGTCCACCACAAGACAGAGTTTGGCTCTAATCTCACTGGCCATGGCTACCCAGATGCCAATTACCTGGATAATGTGCTGGCTGAACTG

>55064_55064_12_MRPL48-DTX4_MRPL48_chr11_73536841_ENST00000542303_DTX4_chr11_58972149_ENST00000532982_length(amino acids)=144AA_BP=67
MSGTLEKVLCLRNNTIFKQAFSLLRFRTSGEKPIYSVGGILLSISRPYKTKPTHGIGKYKHLIKAEEVLKLLLVAWDRRLIFAIGTSSTT

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for MRPL48-DTX4

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for MRPL48-DTX4

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for MRPL48-DTX4

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source