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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:MRPS22-SLC9A9 (FusionGDB2 ID:55165)

Fusion Gene Summary for MRPS22-SLC9A9

check button Fusion gene summary
Fusion gene informationFusion gene name: MRPS22-SLC9A9
Fusion gene ID: 55165
HgeneTgene
Gene symbol

MRPS22

SLC9A9

Gene ID

56945

285195

Gene namemitochondrial ribosomal protein S22solute carrier family 9 member A9
SynonymsC3orf5|COXPD5|GIBT|GK002|MRP-S22|ODG7|RPMS22AUTS16|NHE9
Cytomap

3q23

3q24

Type of geneprotein-codingprotein-coding
Description28S ribosomal protein S22, mitochondrialS22mtmitochondrial small ribosomal subunit protein mS22sodium/hydrogen exchanger 9Na(+)/H(+) exchanger 9putative protein product of Nbla00118sodium/proton exchanger NHE9solute carrier family 9 (sodium/hydrogen exchanger)solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
Modification date2020031320200313
UniProtAcc

P82650

.
Ensembl transtripts involved in fusion geneENST00000310776, ENST00000465056, 
ENST00000478464, ENST00000495075, 
ENST00000489521, 		ENST00000498717, 
ENST00000316549, 
Fusion gene scores* DoF score7 X 7 X 2=988 X 7 X 6=336
# samples 79
** MAII scorelog2(7/98*10)=-0.485426827170242
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/336*10)=-1.90046432644909
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: MRPS22 [Title/Abstract] AND SLC9A9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMRPS22(139071634)-SLC9A9(143412149), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across MRPS22 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC9A9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-67-3774-01AMRPS22chr3

139071634

-SLC9A9chr3

143412149

-
ChimerDB4LUADTCGA-67-3774-01AMRPS22chr3

139071634

+SLC9A9chr3

143412149

-


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Fusion Gene ORF analysis for MRPS22-SLC9A9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000310776ENST00000498717MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
5CDS-intronENST00000465056ENST00000498717MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
5CDS-intronENST00000478464ENST00000498717MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
5CDS-intronENST00000495075ENST00000498717MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
In-frameENST00000310776ENST00000316549MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
In-frameENST00000465056ENST00000316549MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
In-frameENST00000478464ENST00000316549MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
In-frameENST00000495075ENST00000316549MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
intron-3CDSENST00000489521ENST00000316549MRPS22chr3

139071634

+SLC9A9chr3

143412149

-
intron-intronENST00000489521ENST00000498717MRPS22chr3

139071634

+SLC9A9chr3

143412149

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000495075MRPS22chr3139071634+ENST00000316549SLC9A9chr3143412149-419513104232714763
ENST00000310776MRPS22chr3139071634+ENST00000316549SLC9A9chr3143412149-377188682290760
ENST00000465056MRPS22chr3139071634+ENST00000316549SLC9A9chr3143412149-376087502279759
ENST00000478464MRPS22chr3139071634+ENST00000316549SLC9A9chr3143412149-37458601052264719

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000495075ENST00000316549MRPS22chr3139071634+SLC9A9chr3143412149-0.0010799520.9989201
ENST00000310776ENST00000316549MRPS22chr3139071634+SLC9A9chr3143412149-0.0008895780.9991104
ENST00000465056ENST00000316549MRPS22chr3139071634+SLC9A9chr3143412149-0.0012126320.99878734
ENST00000478464ENST00000316549MRPS22chr3139071634+SLC9A9chr3143412149-0.0026560990.99734396

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Fusion Genomic Features for MRPS22-SLC9A9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for MRPS22-SLC9A9


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:139071634/chr3:143412149)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
MRPS22

P82650

.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549316204_224177646.0TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549316236_256177646.0TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549316278_298177646.0TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549316302_322177646.0TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549316323_343177646.0TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549316365_385177646.0TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549316387_407177646.0TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549316430_450177646.0TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549316466_486177646.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549316127_147177646.0TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST00000316549316165_185177646.0TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST0000031654931621_41177646.0TransmembraneHelical
TgeneSLC9A9chr3:139071634chr3:143412149ENST0000031654931646_66177646.0TransmembraneHelical


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Fusion Gene Sequence for MRPS22-SLC9A9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>55165_55165_1_MRPS22-SLC9A9_MRPS22_chr3_139071634_ENST00000310776_SLC9A9_chr3_143412149_ENST00000316549_length(transcript)=3771nt_BP=886nt
TGATAATCATGGCGCCCCTCGGAACAACTGTATTGCTGTGGAGCCTCTTGAGGAGTTCTCCGGGCGTGGAACGGGTCTGTTTCCGGGCTC
GAATCCAGCCCTGGCACGGTGGCCTGCTCCAACCGCTACCTTGCTCTTTCGAGATGGGGCTGCCACGCCGCCGGTTCAGCTCCGAGGCCG
CAGAATCTGGTAGCCCAGAGACCAAGAAACCTACATTTATGGATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGC
AGAAGACTTTTAAGCCAGCTATACAAGAACTGAAGCCACCAACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGG
CAGTTGAGGCAGCTAAAGTACGATTAAAAATGCCACCAGTTCTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTT
TGGAAGGAACAGAAACAACCAAATATGTGTTTACTGATATATCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAA
GTGGCACACTACGCAAAGCCTCTTGGGAAGAACGGGACCGAATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAA
TAATTTTCAAGGAAGAAAATCTTAGGACTATGTATAGCCAGGACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAG
ATTCCACAGAGTATATCAAGGTTCATCACAAGACCTATGAAGATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACT
TTGGTGGAATGGTGTGGTATTTTGTAAATAATAAAAAGATTGATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATG
GTTTTGTGAAGGCTATGATACATGCTGGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTG
CTACAGATCCAGTGACAGTGCTGGCCATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGA
ATGATGCAGTGGCCATAGTCCTTACATATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCC
AGTCTGTGGGGAATTTCCTGGGAATCTTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTA
CCAAGCTGTGTGAGTTCCCGATGCTGGAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAA
CAGGGATAGTTGCTGTTCTCTTCTGTGGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAAC
AGTTGTTTGAATTTATGAACTTTTTGGCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTA
ATGCTCTTTTTATACTTGGAGCCTTTCTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCC
GAAAACAGAAGATCCCCTGGAACTTTCAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACA
CAGAATCTCAGCCCAAACAAATGATGTTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCA
TGTTGACTTGGCTTCAGATCAGAGTTGGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACT
TGGATAAAAACATGACGAAAGCAGAGAGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCC
ACTCTGGTCCTCCGCTGACTACAACATTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGC
TAAAAGAGGATGATGTGGAATGCATTGTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTG
CAAGGCTAGGTCTGGACCAGAAAGCTTCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAAC
TCAAGCTTGAGCAAACTTTGGGTCAATCCCAGTTGAATTAATTGGCATGAAGAGTACAGATGTAATCACAAGTAATGCAAGACTCACTGA
GGAATACAAGCCAAGCTGATGAGGCAGTACAGGGGAGAGGCTGGAAAACATATTAAGAGCATAAATTGGAGAGAATCAAAGCCTTGTCAC
ATGGATCCTCTGGTGCCTGAAGAAATGAGATTTTATTATCCCTCTCTATTATGCAAATGAATTTAGTTTTTTGACAGCAGCCATTCTGAT
TACTGGATTGGCTGGGGTGGGGATGGAGGTATCAGGAGTCTAGCTGCTGGAGGATGGGACAGCTGTGCTGGGTCTTCAGGGCATTTCTGC
TGCGAATGCGGCTCTCCAGGCCCTTCACTTCTATTCTGGATTTTATTCCCTCCATTAAGGAGAGTTTAAAAATAAAAGAAAGCTTCTGAG
AGTAAACATTTTGCTCCTAAGCTGAAGGGAATGCCCAGCTATTTAGTAAGTGATAAGTTTCTTATTTTGAGGACTTGACTCCCATTTGCT
CTCAGTGACCCCAGGGCAGAGCCCAGAGAAGTGTTCCGTACCCACTGCTGATGGTTTCCCAGAGCCCACACTGAGTTGAAGAACCTATTG
TTCTTCTTGGCATCCTTCTTATGCTACTTCTCCCATCGCTCAAAGGGGTTGCCTATGGCTGGGTGTGCCCTGCCCTAAATGCAGCACCAC
TTTCAAGCTTAGTAGGACCATTCCAAGAAAACCAGGTTTCTTCTCCCCATACCACGTTGTGCCTGAAGAACAAGCCTTCCCGTCCTTGCC
TGCATGTGAGTCACTTCTTGGCTGTGCAGCAGGTCCCCCCCTCCCCGCGATATGCTGGAGGGTAGGATTCTGCAGCCTGTGTTGCTCTCT
ACCTGGCAGCAGACTGTGCAGGAGCCCCAACCTGTCCTCCAATTCCAGCATTCACAGCTGATGAGCAGTGCAGGAGCAGGGCGAGAGGAA
CAGAGCCAATGATGTGTGGGTTACACTGAGGAGCCAAGGACAGGGCCTCAGGTCTCCCCCTTACAAGGCGTGGCTCATGGCCTGCATTCC
AGAGACCAACATGATAGCTTTTAATTCAGCTGCATGACCTGTGCCTTTTAAGCCATAAAGATACCTCAAGCCTAGCACCTCTTGAAATCC
AGATGTTCATATTAGACTCGAAAAAATAGGCTCCAGGCCTAGGTGCCCAGGCTATGATGAGTCTGCTTTTGAAGGAGGTAGGGAATGACA
TCTTCCTTGGACCCAAAGCTTAAAAGTAATGTATGCTTTGCTGACCACTGTTTGTTAGGCCTTAAACAACATTCACTGTGGTGGTATCAG
GCACACTGCTATGTGCATCAATTATTTTTTTGCTTTCCAAACAGAATCTCTGGGGCACAAGTTTTACACTCAAGCTAAGTATAACTTTGT

>55165_55165_1_MRPS22-SLC9A9_MRPS22_chr3_139071634_ENST00000310776_SLC9A9_chr3_143412149_ENST00000316549_length(amino acids)=760AA_BP=293
MAPLGTTVLLWSLLRSSPGVERVCFRARIQPWHGGLLQPLPCSFEMGLPRRRFSSEAAESGSPETKKPTFMDEEVQSILTKMTGLNLQKT
FKPAIQELKPPTYKLMTQAQLEEATRQAVEAAKVRLKMPPVLEERVPINDVLAEDKILEGTETTKYVFTDISYSIPHRERFIVVREPSGT
LRKASWEERDRMIQVYFPKEGRKILTPIIFKEENLRTMYSQDRHVDVLNLCFAQFEPDSTEYIKVHHKTYEDIDKRGKYDLLRSTRYFGG
MVWYFVNNKKIDGLLIDQIQRDLLIMYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDA
VAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGI
VAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQ
KIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDK
NMTKAESARLFRMWYSFDHKYLKPILTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCSPPARL

--------------------------------------------------------------
>55165_55165_2_MRPS22-SLC9A9_MRPS22_chr3_139071634_ENST00000465056_SLC9A9_chr3_143412149_ENST00000316549_length(transcript)=3760nt_BP=875nt
ATGGCGCCCCTCGGAACAACTGTATTGCTGTGGAGCCTCTTGAGGAGTTCTCCGGGCGTGGAACGGGTCTGTTTCCGGGCTCGAATCCAG
CCCTGGCACGGTGGCCTGCTCCAACCGCTACCTTGCTCTTTCGAGATGGGGCTGCCACGCCGCCGGTTCAGCTCCGAGGCCGAATCTGGT
AGCCCAGAGACCAAGAAACCTACATTTATGGATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGCAGAAGACTTTT
AAGCCAGCTATACAAGAACTGAAGCCACCAACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGGCAGTTGAGGCA
GCTAAAGTACGATTAAAAATGCCACCAGTTCTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTTTGGAAGGAACA
GAAACAACCAAATATGTGTTTACTGATATATCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAAGTGGCACACTA
CGCAAAGCCTCTTGGGAAGAACGGGACCGAATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAATAATTTTCAAG
GAAGAAAATCTTAGGACTATGTATAGCCAGGACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAGATTCCACAGAG
TATATCAAGGTTCATCACAAGACCTATGAAGATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACTTTGGTGGAATG
GTGTGGTATTTTGTAAATAATAAAAAGATTGATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATGGTTTTGTGAAG
GCTATGATACATGCTGGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTGCTACAGATCCA
GTGACAGTGCTGGCCATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGAATGATGCAGTG
GCCATAGTCCTTACATATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCCAGTCTGTGGGG
AATTTCCTGGGAATCTTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTACCAAGCTGTGT
GAGTTCCCGATGCTGGAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAACAGGGATAGTT
GCTGTTCTCTTCTGTGGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAACAGTTGTTTGAA
TTTATGAACTTTTTGGCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTAATGCTCTTTTT
ATACTTGGAGCCTTTCTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCCGAAAACAGAAG
ATCCCCTGGAACTTTCAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACACAGAATCTCAG
CCCAAACAAATGATGTTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCATGTTGACTTGG
CTTCAGATCAGAGTTGGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACTTGGATAAAAAC
ATGACGAAAGCAGAGAGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCCACTCTGGTCCT
CCGCTGACTACAACATTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGCTAAAAGAGGAT
GATGTGGAATGCATTGTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTGCAAGGCTAGGT
CTGGACCAGAAAGCTTCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAACTCAAGCTTGAG
CAAACTTTGGGTCAATCCCAGTTGAATTAATTGGCATGAAGAGTACAGATGTAATCACAAGTAATGCAAGACTCACTGAGGAATACAAGC
CAAGCTGATGAGGCAGTACAGGGGAGAGGCTGGAAAACATATTAAGAGCATAAATTGGAGAGAATCAAAGCCTTGTCACATGGATCCTCT
GGTGCCTGAAGAAATGAGATTTTATTATCCCTCTCTATTATGCAAATGAATTTAGTTTTTTGACAGCAGCCATTCTGATTACTGGATTGG
CTGGGGTGGGGATGGAGGTATCAGGAGTCTAGCTGCTGGAGGATGGGACAGCTGTGCTGGGTCTTCAGGGCATTTCTGCTGCGAATGCGG
CTCTCCAGGCCCTTCACTTCTATTCTGGATTTTATTCCCTCCATTAAGGAGAGTTTAAAAATAAAAGAAAGCTTCTGAGAGTAAACATTT
TGCTCCTAAGCTGAAGGGAATGCCCAGCTATTTAGTAAGTGATAAGTTTCTTATTTTGAGGACTTGACTCCCATTTGCTCTCAGTGACCC
CAGGGCAGAGCCCAGAGAAGTGTTCCGTACCCACTGCTGATGGTTTCCCAGAGCCCACACTGAGTTGAAGAACCTATTGTTCTTCTTGGC
ATCCTTCTTATGCTACTTCTCCCATCGCTCAAAGGGGTTGCCTATGGCTGGGTGTGCCCTGCCCTAAATGCAGCACCACTTTCAAGCTTA
GTAGGACCATTCCAAGAAAACCAGGTTTCTTCTCCCCATACCACGTTGTGCCTGAAGAACAAGCCTTCCCGTCCTTGCCTGCATGTGAGT
CACTTCTTGGCTGTGCAGCAGGTCCCCCCCTCCCCGCGATATGCTGGAGGGTAGGATTCTGCAGCCTGTGTTGCTCTCTACCTGGCAGCA
GACTGTGCAGGAGCCCCAACCTGTCCTCCAATTCCAGCATTCACAGCTGATGAGCAGTGCAGGAGCAGGGCGAGAGGAACAGAGCCAATG
ATGTGTGGGTTACACTGAGGAGCCAAGGACAGGGCCTCAGGTCTCCCCCTTACAAGGCGTGGCTCATGGCCTGCATTCCAGAGACCAACA
TGATAGCTTTTAATTCAGCTGCATGACCTGTGCCTTTTAAGCCATAAAGATACCTCAAGCCTAGCACCTCTTGAAATCCAGATGTTCATA
TTAGACTCGAAAAAATAGGCTCCAGGCCTAGGTGCCCAGGCTATGATGAGTCTGCTTTTGAAGGAGGTAGGGAATGACATCTTCCTTGGA
CCCAAAGCTTAAAAGTAATGTATGCTTTGCTGACCACTGTTTGTTAGGCCTTAAACAACATTCACTGTGGTGGTATCAGGCACACTGCTA
TGTGCATCAATTATTTTTTTGCTTTCCAAACAGAATCTCTGGGGCACAAGTTTTACACTCAAGCTAAGTATAACTTTGTCATTTCAGGTA

>55165_55165_2_MRPS22-SLC9A9_MRPS22_chr3_139071634_ENST00000465056_SLC9A9_chr3_143412149_ENST00000316549_length(amino acids)=759AA_BP=292
MAPLGTTVLLWSLLRSSPGVERVCFRARIQPWHGGLLQPLPCSFEMGLPRRRFSSEAESGSPETKKPTFMDEEVQSILTKMTGLNLQKTF
KPAIQELKPPTYKLMTQAQLEEATRQAVEAAKVRLKMPPVLEERVPINDVLAEDKILEGTETTKYVFTDISYSIPHRERFIVVREPSGTL
RKASWEERDRMIQVYFPKEGRKILTPIIFKEENLRTMYSQDRHVDVLNLCFAQFEPDSTEYIKVHHKTYEDIDKRGKYDLLRSTRYFGGM
VWYFVNNKKIDGLLIDQIQRDLLIMYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAV
AIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIV
AVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQK
IPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKN
MTKAESARLFRMWYSFDHKYLKPILTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCSPPARLG

--------------------------------------------------------------
>55165_55165_3_MRPS22-SLC9A9_MRPS22_chr3_139071634_ENST00000478464_SLC9A9_chr3_143412149_ENST00000316549_length(transcript)=3745nt_BP=860nt
GGAAGGTCAGGGAAGGGTTCCTGGCAAATATGACCAAAGCTGAGATCTGGTTAGCCATGCTAAGGAGAAAGCAAGAAGCTTCTCAAGCAT
AGGGGACAGTAGCAGATGTCCAGAAATGAGACTGAGCACAGATATTTGGGAACCCATTTTGGAGCAGAATCTGGTAGCCCAGAGACCAAG
AAACCTACATTTATGGATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGCAGAAGACTTTTAAGCCAGCTATACAA
GAACTGAAGCCACCAACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGGCAGTTGAGGCAGCTAAAGTACGATTA
AAAATGCCACCAGTTCTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTTTGGAAGGAACAGAAACAACCAAATAT
GTGTTTACTGATATATCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAAGTGGCACACTACGCAAAGCCTCTTGG
GAAGAACGGGACCGAATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAATAATTTTCAAGGAAGAAAATCTTAGG
ACTATGTATAGCCAGGACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAGATTCCACAGAGTATATCAAGGTTCAT
CACAAGACCTATGAAGATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACTTTGGTGGAATGGTGTGGTATTTTGTA
AATAATAAAAAGATTGATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATGGTTTTGTGAAGGCTATGATACATGCT
GGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTGCTACAGATCCAGTGACAGTGCTGGCC
ATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGAATGATGCAGTGGCCATAGTCCTTACA
TATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCCAGTCTGTGGGGAATTTCCTGGGAATC
TTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTACCAAGCTGTGTGAGTTCCCGATGCTG
GAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAACAGGGATAGTTGCTGTTCTCTTCTGT
GGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAACAGTTGTTTGAATTTATGAACTTTTTG
GCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTAATGCTCTTTTTATACTTGGAGCCTTT
CTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCCGAAAACAGAAGATCCCCTGGAACTTT
CAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACACAGAATCTCAGCCCAAACAAATGATG
TTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCATGTTGACTTGGCTTCAGATCAGAGTT
GGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACTTGGATAAAAACATGACGAAAGCAGAG
AGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCCACTCTGGTCCTCCGCTGACTACAACA
TTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGCTAAAAGAGGATGATGTGGAATGCATT
GTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTGCAAGGCTAGGTCTGGACCAGAAAGCT
TCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAACTCAAGCTTGAGCAAACTTTGGGTCAA
TCCCAGTTGAATTAATTGGCATGAAGAGTACAGATGTAATCACAAGTAATGCAAGACTCACTGAGGAATACAAGCCAAGCTGATGAGGCA
GTACAGGGGAGAGGCTGGAAAACATATTAAGAGCATAAATTGGAGAGAATCAAAGCCTTGTCACATGGATCCTCTGGTGCCTGAAGAAAT
GAGATTTTATTATCCCTCTCTATTATGCAAATGAATTTAGTTTTTTGACAGCAGCCATTCTGATTACTGGATTGGCTGGGGTGGGGATGG
AGGTATCAGGAGTCTAGCTGCTGGAGGATGGGACAGCTGTGCTGGGTCTTCAGGGCATTTCTGCTGCGAATGCGGCTCTCCAGGCCCTTC
ACTTCTATTCTGGATTTTATTCCCTCCATTAAGGAGAGTTTAAAAATAAAAGAAAGCTTCTGAGAGTAAACATTTTGCTCCTAAGCTGAA
GGGAATGCCCAGCTATTTAGTAAGTGATAAGTTTCTTATTTTGAGGACTTGACTCCCATTTGCTCTCAGTGACCCCAGGGCAGAGCCCAG
AGAAGTGTTCCGTACCCACTGCTGATGGTTTCCCAGAGCCCACACTGAGTTGAAGAACCTATTGTTCTTCTTGGCATCCTTCTTATGCTA
CTTCTCCCATCGCTCAAAGGGGTTGCCTATGGCTGGGTGTGCCCTGCCCTAAATGCAGCACCACTTTCAAGCTTAGTAGGACCATTCCAA
GAAAACCAGGTTTCTTCTCCCCATACCACGTTGTGCCTGAAGAACAAGCCTTCCCGTCCTTGCCTGCATGTGAGTCACTTCTTGGCTGTG
CAGCAGGTCCCCCCCTCCCCGCGATATGCTGGAGGGTAGGATTCTGCAGCCTGTGTTGCTCTCTACCTGGCAGCAGACTGTGCAGGAGCC
CCAACCTGTCCTCCAATTCCAGCATTCACAGCTGATGAGCAGTGCAGGAGCAGGGCGAGAGGAACAGAGCCAATGATGTGTGGGTTACAC
TGAGGAGCCAAGGACAGGGCCTCAGGTCTCCCCCTTACAAGGCGTGGCTCATGGCCTGCATTCCAGAGACCAACATGATAGCTTTTAATT
CAGCTGCATGACCTGTGCCTTTTAAGCCATAAAGATACCTCAAGCCTAGCACCTCTTGAAATCCAGATGTTCATATTAGACTCGAAAAAA
TAGGCTCCAGGCCTAGGTGCCCAGGCTATGATGAGTCTGCTTTTGAAGGAGGTAGGGAATGACATCTTCCTTGGACCCAAAGCTTAAAAG
TAATGTATGCTTTGCTGACCACTGTTTGTTAGGCCTTAAACAACATTCACTGTGGTGGTATCAGGCACACTGCTATGTGCATCAATTATT
TTTTTGCTTTCCAAACAGAATCTCTGGGGCACAAGTTTTACACTCAAGCTAAGTATAACTTTGTCATTTCAGGTAAATATGACAAGTGGT

>55165_55165_3_MRPS22-SLC9A9_MRPS22_chr3_139071634_ENST00000478464_SLC9A9_chr3_143412149_ENST00000316549_length(amino acids)=719AA_BP=252
MSRNETEHRYLGTHFGAESGSPETKKPTFMDEEVQSILTKMTGLNLQKTFKPAIQELKPPTYKLMTQAQLEEATRQAVEAAKVRLKMPPV
LEERVPINDVLAEDKILEGTETTKYVFTDISYSIPHRERFIVVREPSGTLRKASWEERDRMIQVYFPKEGRKILTPIIFKEENLRTMYSQ
DRHVDVLNLCFAQFEPDSTEYIKVHHKTYEDIDKRGKYDLLRSTRYFGGMVWYFVNNKKIDGLLIDQIQRDLLIMYGFVKAMIHAGQLKN
GDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVLNDAVAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSF
AMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGLTGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFLAENVI
FCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLGRKQKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTL
LLVFFTVWVFGGGTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANNLDKNMTKAESARLFRMWYSFDHKYLKPILTHSGPPLTTTLPEWC

--------------------------------------------------------------
>55165_55165_4_MRPS22-SLC9A9_MRPS22_chr3_139071634_ENST00000495075_SLC9A9_chr3_143412149_ENST00000316549_length(transcript)=4195nt_BP=1310nt
CCTCTTCCTGGGCGGCGATCTCTGGGACAGATGCGCAGAAGACTTCCTGCTCAACGACGACGTCCTCCCTGAGAGCGCCCAGGAAAACGT
CCACTTCCAGCCCAGCAGACGAGTCGTCCTGCGCTCCTGAGCGTTCGTCGACAGAGCTCAGGAGGACCTCTGGGATCAGGATGAGGGTGT
GTCCATCGAGAGACACTCGCAGGATCGACGTTGGCGGGAGCTCCAGCACCAGGTCGACGTCGTCCAGGGGCACACGCAGGGCACAGCCCG
CGGCCAGGACCACTATGGAGCACTTTGAGTATATCATCCCACTGTCTCCTGGAGGGCAAGATTCAGCCTTAAGGGGGTTCCCTTGTATGT
GAGTGCTGCAAGAACTGGGTGTGACTCGGAATCCCTCCCAACCACTTCCGGCGCAAGTGGCTTCTGATAATCATGGCGCCCCTCGGAACA
ACTGTATTGCTGTGGAGCCTCTTGAGGAGTTCTCCGGGCGTGGAACGGGTCTGTTTCCGGGCTCGAATCCAGCCCTGGCACGGTGGCCTG
CTCCAACCGCTACCTTGCTCTTTCGAGATGGGGCTGCCACGCCGCCGGTTCAGCTCCGAGGCCGCAGAATCTGGTAGCCCAGAGACCAAG
AAACCTACATTTATGGATGAGGAAGTTCAAAGCATACTCACGAAAATGACAGGCTTGAACTTGCAGAAGACTTTTAAGCCAGCTATACAA
GAACTGAAGCCACCAACCTATAAGCTAATGACTCAGGCACAGTTGGAAGAGGCTACAAGACAGGCAGTTGAGGCAGCTAAAGTACGATTA
AAAATGCCACCAGTTCTGGAAGAGCGAGTACCAATAAATGATGTGTTAGCTGAAGATAAGATTTTGGAAGGAACAGAAACAACCAAATAT
GTGTTTACTGATATATCATATAGCATACCACACCGGGAGCGTTTTATTGTCGTCAGAGAACCAAGTGGCACACTACGCAAAGCCTCTTGG
GAAGAACGGGACCGAATGATACAAGTTTATTTCCCAAAAGAAGGTCGTAAAATTTTGACACCAATAATTTTCAAGGAAGAAAATCTTAGG
ACTATGTATAGCCAGGACAGGCATGTTGATGTCCTCAATCTCTGCTTTGCCCAGTTTGAGCCAGATTCCACAGAGTATATCAAGGTTCAT
CACAAGACCTATGAAGATATAGATAAACGTGGAAAATATGACCTTTTACGTTCAACAAGATACTTTGGTGGAATGGTGTGGTATTTTGTA
AATAATAAAAAGATTGATGGTTTGCTGATTGACCAGATTCAGAGAGATTTGTTAATTATGTATGGTTTTGTGAAGGCTATGATACATGCT
GGCCAGCTGAAAAATGGAGACTTTCATTTCACTGACTGTTTATTTTTTGGTTCACTGATGTCTGCTACAGATCCAGTGACAGTGCTGGCC
ATTTTCCATGAACTGCACGTCGACCCTGACCTGTACACACTCTTGTTTGGAGAGAGTGTGTTGAATGATGCAGTGGCCATAGTCCTTACA
TATTCTATATCCATTTACAGTCCCAAGGAGAATCCAAATGCATTTGATGCCGCAGCATTCTTCCAGTCTGTGGGGAATTTCCTGGGAATC
TTCGCTGGCTCATTTGCAATGGGGTCTGCGTATGCCATCATCACAGCACTGTTGACCAAATTTACCAAGCTGTGTGAGTTCCCGATGCTG
GAAACCGGCCTGTTTTTCCTGCTTTCTTGGAGTGCCTTCCTGTCTGCCGAGGCTGCCGGCCTAACAGGGATAGTTGCTGTTCTCTTCTGT
GGAGTCACACAAGCACATTATACCTACAACAATCTGTCTTCGGATTCCAAAATAAGAACTAAACAGTTGTTTGAATTTATGAACTTTTTG
GCGGAGAACGTCATCTTCTGTTACATGGGCCTGGCACTGTTCACGTTCCAGAATCATATCTTTAATGCTCTTTTTATACTTGGAGCCTTT
CTAGCAATTTTTGTTGCCAGAGCCTGCAACATATATCCCCTCTCCTTCCTCCTGAATCTAGGCCGAAAACAGAAGATCCCCTGGAACTTT
CAGCACATGATGATGTTTTCAGGTTTGCGAGGAGCGATCGCATTTGCCTTAGCTATTCGGAACACAGAATCTCAGCCCAAACAAATGATG
TTTACCACTACGCTGCTCCTCGTGTTCTTCACTGTCTGGGTATTTGGAGGAGGAACAACCCCCATGTTGACTTGGCTTCAGATCAGAGTT
GGCGTGGACCTGGATGAAAATCTGAAGGAGGACCCCTCCTCACAACACCAGGAAGCAAATAACTTGGATAAAAACATGACGAAAGCAGAG
AGTGCTCGGCTCTTCAGAATGTGGTATAGCTTTGACCACAAGTATCTGAAACCAATTTTAACCCACTCTGGTCCTCCGCTGACTACAACA
TTACCTGAATGGTGTGGTCCGATTTCCAGGCTGCTTACCAGTCCTCAAGCCTATGGGGAACAGCTAAAAGAGGATGATGTGGAATGCATT
GTAAACCAGGATGAACTAGCCATAAATTACCAGGAGCAAGCCTCCTCACCCTGCAGTCCTCCTGCAAGGCTAGGTCTGGACCAGAAAGCT
TCACCCCAGACGCCAGGCAAGGAAAACATTTATGAGGGAGACCTCGGCCTGGGAGGCTATGAACTCAAGCTTGAGCAAACTTTGGGTCAA
TCCCAGTTGAATTAATTGGCATGAAGAGTACAGATGTAATCACAAGTAATGCAAGACTCACTGAGGAATACAAGCCAAGCTGATGAGGCA
GTACAGGGGAGAGGCTGGAAAACATATTAAGAGCATAAATTGGAGAGAATCAAAGCCTTGTCACATGGATCCTCTGGTGCCTGAAGAAAT
GAGATTTTATTATCCCTCTCTATTATGCAAATGAATTTAGTTTTTTGACAGCAGCCATTCTGATTACTGGATTGGCTGGGGTGGGGATGG
AGGTATCAGGAGTCTAGCTGCTGGAGGATGGGACAGCTGTGCTGGGTCTTCAGGGCATTTCTGCTGCGAATGCGGCTCTCCAGGCCCTTC
ACTTCTATTCTGGATTTTATTCCCTCCATTAAGGAGAGTTTAAAAATAAAAGAAAGCTTCTGAGAGTAAACATTTTGCTCCTAAGCTGAA
GGGAATGCCCAGCTATTTAGTAAGTGATAAGTTTCTTATTTTGAGGACTTGACTCCCATTTGCTCTCAGTGACCCCAGGGCAGAGCCCAG
AGAAGTGTTCCGTACCCACTGCTGATGGTTTCCCAGAGCCCACACTGAGTTGAAGAACCTATTGTTCTTCTTGGCATCCTTCTTATGCTA
CTTCTCCCATCGCTCAAAGGGGTTGCCTATGGCTGGGTGTGCCCTGCCCTAAATGCAGCACCACTTTCAAGCTTAGTAGGACCATTCCAA
GAAAACCAGGTTTCTTCTCCCCATACCACGTTGTGCCTGAAGAACAAGCCTTCCCGTCCTTGCCTGCATGTGAGTCACTTCTTGGCTGTG
CAGCAGGTCCCCCCCTCCCCGCGATATGCTGGAGGGTAGGATTCTGCAGCCTGTGTTGCTCTCTACCTGGCAGCAGACTGTGCAGGAGCC
CCAACCTGTCCTCCAATTCCAGCATTCACAGCTGATGAGCAGTGCAGGAGCAGGGCGAGAGGAACAGAGCCAATGATGTGTGGGTTACAC
TGAGGAGCCAAGGACAGGGCCTCAGGTCTCCCCCTTACAAGGCGTGGCTCATGGCCTGCATTCCAGAGACCAACATGATAGCTTTTAATT
CAGCTGCATGACCTGTGCCTTTTAAGCCATAAAGATACCTCAAGCCTAGCACCTCTTGAAATCCAGATGTTCATATTAGACTCGAAAAAA
TAGGCTCCAGGCCTAGGTGCCCAGGCTATGATGAGTCTGCTTTTGAAGGAGGTAGGGAATGACATCTTCCTTGGACCCAAAGCTTAAAAG
TAATGTATGCTTTGCTGACCACTGTTTGTTAGGCCTTAAACAACATTCACTGTGGTGGTATCAGGCACACTGCTATGTGCATCAATTATT
TTTTTGCTTTCCAAACAGAATCTCTGGGGCACAAGTTTTACACTCAAGCTAAGTATAACTTTGTCATTTCAGGTAAATATGACAAGTGGT

>55165_55165_4_MRPS22-SLC9A9_MRPS22_chr3_139071634_ENST00000495075_SLC9A9_chr3_143412149_ENST00000316549_length(amino acids)=763AA_BP=296
MIIMAPLGTTVLLWSLLRSSPGVERVCFRARIQPWHGGLLQPLPCSFEMGLPRRRFSSEAAESGSPETKKPTFMDEEVQSILTKMTGLNL
QKTFKPAIQELKPPTYKLMTQAQLEEATRQAVEAAKVRLKMPPVLEERVPINDVLAEDKILEGTETTKYVFTDISYSIPHRERFIVVREP
SGTLRKASWEERDRMIQVYFPKEGRKILTPIIFKEENLRTMYSQDRHVDVLNLCFAQFEPDSTEYIKVHHKTYEDIDKRGKYDLLRSTRY
FGGMVWYFVNNKKIDGLLIDQIQRDLLIMYGFVKAMIHAGQLKNGDFHFTDCLFFGSLMSATDPVTVLAIFHELHVDPDLYTLLFGESVL
NDAVAIVLTYSISIYSPKENPNAFDAAAFFQSVGNFLGIFAGSFAMGSAYAIITALLTKFTKLCEFPMLETGLFFLLSWSAFLSAEAAGL
TGIVAVLFCGVTQAHYTYNNLSSDSKIRTKQLFEFMNFLAENVIFCYMGLALFTFQNHIFNALFILGAFLAIFVARACNIYPLSFLLNLG
RKQKIPWNFQHMMMFSGLRGAIAFALAIRNTESQPKQMMFTTTLLLVFFTVWVFGGGTTPMLTWLQIRVGVDLDENLKEDPSSQHQEANN
LDKNMTKAESARLFRMWYSFDHKYLKPILTHSGPPLTTTLPEWCGPISRLLTSPQAYGEQLKEDDVECIVNQDELAINYQEQASSPCSPP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for MRPS22-SLC9A9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for MRPS22-SLC9A9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for MRPS22-SLC9A9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource